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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3166 | - | - | 100% (487) | putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3559 | - | 2e-87 | 51.19% (336) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_4313 | - | 4e-61 | 37.14% (447) | PUTATIVE putative AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0276 | fadD2 | 5e-37 | 27.40% (500) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_4362 | - | 1e-108 | 46.52% (488) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0270 | fadD2 | 5e-37 | 27.40% (500) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 3e-36 | 27.25% (499) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4569c | - | 1e-36 | 28.77% (504) | fatty-acid-CoA ligase FadD |
| M. marinum M | MMAR_4025 | - | 5e-98 | 44.03% (486) | long-chain fatty-acid CoA ligase |
| M. avium 104 | MAV_1580 | - | 1e-108 | 45.71% (490) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_2217 | - | 1e-108 | 46.34% (492) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_3890 | - | 5e-96 | 43.30% (485) | long-chain fatty-acid CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_1982 | - | 1e-113 | 46.31% (488) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1982|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2217|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4025|M.marinum_M --------------------------------------------------
MUL_3890|M.ulcerans_Agy99 --------------------------------------------------
MAV_1580|M.avium_104 --------------------------------------------------
TH_3166|M.thermoresistible__bu --------------------------------------------------
Mb0276|M.bovis_AF2122/97 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
Rv0270|M.tuberculosis_H37Rv MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
MLBr_02546|M.leprae_Br4923 -----------MTKLR----HYLERGAAEVHYLRSIFESGALGFEPPLTY
MAB_4569c|M.abscessus_ATCC_199 --------------------------------------MTDTIDATVQSA
Mflv_4362|M.gilvum_PYR-GCK ---------MHPLSRRIAEVMALDASAPAIQFERRWVTWGQIAESARHVS
Mvan_1982|M.vanbaalenii_PYR-1 -------MMVHRLSQRIDDVLALAPAGRAIQFDGDWVTWEQIGTLAQRIS
MSMEG_2217|M.smegmatis_MC2_155 --------MAHPLSQRIADVLDLDPDAGAIQFDGQWSCWGQIAALAGHIE
MMAR_4025|M.marinum_M -------MSNHPLSQRIADTLDLQPDARAVEYDRAWLSWGQLGAATRRVA
MUL_3890|M.ulcerans_Agy99 -------MSNHPLSQRIAVTLDLQPDARAVEYDRAWLSLGQLGAATRRVA
MAV_1580|M.avium_104 -------MPRHPLVQRIADVLDLEPHGRAIEYGGQWFSWAQLGATARQVA
TH_3166|M.thermoresistible__bu -------------------VLALDPSAEAVEYQGAWTDWKTVAHVAHAVE
Mb0276|M.bovis_AF2122/97 AALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVA
Rv0270|M.tuberculosis_H37Rv AALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVA
MLBr_02546|M.leprae_Br4923 AAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALA
MAB_4569c|M.abscessus_ATCC_199 GLAQPYRARRQNWCNQLARHALMQPDATAIRYLGHSISWAELHQRVQALA
. *: : . :
Mflv_4362|M.gilvum_PYR-GCK TVVGS------GTAGIMLRNTPSHVAALLGVLSGGGTVVVINPSRGDERT
Mvan_1982|M.vanbaalenii_PYR-1 DVVGT------ARAGIMLRNRPVHVAALLGVLRGGGTVVVINPSRGDDRT
MSMEG_2217|M.smegmatis_MC2_155 KITGP------ARVGIMLRNHPVHVAALLGVLAAGGTVVVINPARGDDRT
MMAR_4025|M.marinum_M ALAARQ---PSPEIGILLRSRPAQMAAFLGVLLSGATVVTINPSRGDERT
MUL_3890|M.ulcerans_Agy99 ALAAKQ---PSPEIGILLRNRPAQMAAFLGVLLAGATVVTINPSRGDERT
MAV_1580|M.avium_104 ARTTG------TEVGMLLRNRPWQVAAFLGVLLGGGTVVVVNPSRGDERT
TH_3166|M.thermoresistible__bu SRLTAAGLGAGSPVGLILRNHPAMVAALLGVLLVNGCVVTINASSGDARL
Mb0276|M.bovis_AF2122/97 NGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQI
Rv0270|M.tuberculosis_H37Rv NGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQI
MLBr_02546|M.leprae_Br4923 NGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQI
MAB_4569c|M.abscessus_ATCC_199 DALSRRGVGFGDRVLILMLNRPEYVESWLAINELGAIAIPVNFRMTPPEV
:: . : : . .. : :* .
Mflv_4362|M.gilvum_PYR-GCK RADIEALQLPTLIGLAEDLESLAPGTT--ATTMALGDIDTTPEITGGS-P
Mvan_1982|M.vanbaalenii_PYR-1 RSDVEALNLPIIIGSSEDLAALAPDTA--ATTVAVDGFDEPPTLHRGN-A
MSMEG_2217|M.smegmatis_MC2_155 RADLEALALPVVVGLAEDLAHLMPAHSPRTTRVAIAGLDTEPVVTAAESP
MMAR_4025|M.marinum_M RADIAALELPLIAGSDEDLGLLVTNTTDSATVSLSDLFDHPGEPGDHTTR
MUL_3890|M.ulcerans_Agy99 RADIAALELPLIAGSDEDLGLLVTNTTDSATVSLSDLFDHPGEPGGHTTR
MAV_1580|M.avium_104 RADLARLRLPLIIGEPDDLAALVT--DDTPTMPISRLADPPGP--AAPPA
TH_3166|M.thermoresistible__bu ATDLEELRLPVVIGLGADWGRPHIVEAAAGALGLEVAADPASVRTVTGRG
Mb0276|M.bovis_AF2122/97 KEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE
Rv0270|M.tuberculosis_H37Rv KEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE
MLBr_02546|M.leprae_Br4923 KEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDE
MAB_4569c|M.abscessus_ATCC_199 AFLVENSGAKVAITETVLAPVAAAVRQQAPALETVIVAGSASENGVLGYE
Mflv_4362|M.gilvum_PYR-GCK SEGQ------------HRPGVAVRMPTSGTTGPPKRVDLTYDMLARSVMG
Mvan_1982|M.vanbaalenii_PYR-1 SDDA------------GRPGVAVWMLTSGTTGPPKRVDLTYDMLARSVMG
MSMEG_2217|M.smegmatis_MC2_155 ATDA------------GGPGVAVWMLTSGTTGPPKRVDLTYDMLARSVMG
MMAR_4025|M.marinum_M GAG---------------ADVAVRMLTSGTTGPPKRVDLSYDMLARSVMG
MUL_3890|M.ulcerans_Agy99 GAG---------------ADVAVRMLTSGTTGPPNRVDLSYDMLARSVMG
MAV_1580|M.avium_104 AAP---------------RSVAVRMLTSGTTGPPKRIDLGYDMLARSVLG
TH_3166|M.thermoresistible__bu SVGAGPFRP-------DRPGVAVEMLTSGTTGPPKRVPLSYNAFQHTVAA
Mb0276|M.bovis_AF2122/97 TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG
Rv0270|M.tuberculosis_H37Rv TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG
MLBr_02546|M.leprae_Br4923 TLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGG
MAB_4569c|M.abscessus_ATCC_199 EVIAEPGEP-HAEVDLPGDTPALIMYTSGTTGRPKGAVLTHLNLSGQAMT
:: : ****** *:
Mflv_4362|M.gilvum_PYR-GCK RDPDT---APSPTELRQGVAIVNSPLVHVGGVFRILLCLAEARPFVLLPK
Mvan_1982|M.vanbaalenii_PYR-1 PDSDH---DSAPTDLRRGVAIVNSPLVHVGGVFRVLLCVAEARPFVLLPK
MSMEG_2217|M.smegmatis_MC2_155 REPEK---CPAPTELRRGVAIVNSPLVHVGGVFRVLLCIAEARPFVLLPK
MMAR_4025|M.marinum_M PAPDR---DPAPTEPRRGVAIVNSPLVHIGGVYRVLQCIAQARPFVLLDR
MUL_3890|M.ulcerans_Agy99 PAPDR---DPAPTEPRRGVAIVNSPLVHIGGVYRVLQCIAQARPFVLLDR
MAV_1580|M.avium_104 VEPGT---APAPTEPRRGVAIVNSPLVHIGGVFRVLQCIADARPFVLLER
TH_3166|M.thermoresistible__bu AGAHYGSGDNGQVRLRSGVAIISSPLVHMSGLFRTLLNICEGRRIALLER
Mb0276|M.bovis_AF2122/97 ILSHVP-------FKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRR
Rv0270|M.tuberculosis_H37Rv ILSHVP-------FKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRR
MLBr_02546|M.leprae_Br4923 ILSKVP-------FRAHEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRR
MAB_4569c|M.abscessus_ATCC_199 YLLSTT------VDLNSDVGFIGVPMFHIAGVGNMITGLLLGLPTVIHPL
* :: *:.* * . : . .:
Mflv_4362|M.gilvum_PYR-GCK --FELHSWAEAVREHRPAAVSLVPAALR---MVLHSDLTRDDLAGVRVVT
Mvan_1982|M.vanbaalenii_PYR-1 --FELKQWADAVREHRPRAVSLVPAALR---MVLHSDLTREDLDGIRVVT
MSMEG_2217|M.smegmatis_MC2_155 --FELQRWAAAVREHRPRAVSLVPAALR---TVLHSDLTREDLAGVRVVT
MMAR_4025|M.marinum_M --FELNAWAAAVRKHRPRTVSLVPAALR---TVLHSDLTRADLASVRTVT
MUL_3890|M.ulcerans_Agy99 --FELNARAAAVRKHRPRTVSLVPAALR---TVLHSDPTRADLASVRTVT
MAV_1580|M.avium_104 --FELNAWAAAVRRHRPRAVSLVPAALR---TVLHSDLPRADLESIQVVT
TH_3166|M.thermoresistible__bu --FRVDDFVDLVVRHQPKAVSLVPSALA---MVLDAGVPPEVFSSVKVVT
Mb0276|M.bovis_AF2122/97 --FKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVF
Rv0270|M.tuberculosis_H37Rv --FKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVF
MLBr_02546|M.leprae_Br4923 --FKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVF
MAB_4569c|M.abscessus_ATCC_199 GAFDPGALLDVLESEGVTGIFLVPAQWQ---AVCAAQQANPRKVRLKTLS
* : . : :** . :: :
Mflv_4362|M.gilvum_PYR-GCK SGTAPLSADDAEAFTAKFG-IPVLTSYAATEFGGGVAGWTLADHRKYWQD
Mvan_1982|M.vanbaalenii_PYR-1 SGTAPLSADDADAFTEKFG-IPVLTSYAATEFGGGVAGWTLKDHQRFWQH
MSMEG_2217|M.smegmatis_MC2_155 SGTAPLSADDADAFTEKFG-IPVLTSYAATEFGGGVAGWTLPDHGKYWKD
MMAR_4025|M.marinum_M CGTAPLAPDDADAFTEKYG-IPVLTSYAATEFGGGVAGWTLADHSRYWHT
MUL_3890|M.ulcerans_Agy99 CGTAPLAPDDADAFTEKYG-IPVLTSYAATEFGGGVAGWTLADHSRYWHT
MAV_1580|M.avium_104 CGTAPLSADDADAFTEKYG-IPVLTSYAATEFGGGVAGWTLADHRRYWRV
TH_3166|M.thermoresistible__bu SGTAPLPVELQEAFEERYD-VAVLPSYGATEFAGGVAGWNLALHREWAKI
Mb0276|M.bovis_AF2122/97 VSGSQLGAELATRALGDLG-PVIYNMYGSTEVA-----FATIAGPKDLQF
Rv0270|M.tuberculosis_H37Rv VSGSQLGAELATRALGDLG-PVIYNMYGSTEVA-----FATIAGPKDLQF
MLBr_02546|M.leprae_Br4923 VSGSQLGAELATRALEELG-PVIYNMYGSTEIA-----FATIAGPKDLQI
MAB_4569c|M.abscessus_ATCC_199 WGAAPATDVLLRTMSETFPDARILAAFGQTEMSP----VTCMLMGDDAIR
. : : :. **..
Mflv_4362|M.gilvum_PYR-GCK KRGSVGRANPGARLRVVD-DNRDPVPPGEPGLLEVIPAQLAD--------
Mvan_1982|M.vanbaalenii_PYR-1 KRGSVGRANPGAQLRVVD-DNGEPVPPGQQGLLEVIPAQLAG--------
MSMEG_2217|M.smegmatis_MC2_155 KRGSVGRANPGAQLRVVD-ENGAPLGPDEPGLLEVIPAQMGP--------
MMAR_4025|M.marinum_M KRGSVGRANPGTQLRIVD-TEGAPVERASLGLLEVKPAQLGV--------
MUL_3890|M.ulcerans_Agy99 KRGSVGRANPGTQLRIVD-TEGAPVERASLGLLEVKPAQLGV--------
MAV_1580|M.avium_104 KRGSVGRANPGAALRVVA-EDGTPLGPDEIGLMEVKPGQLGP--------
TH_3166|M.thermoresistible__bu KRGSVGRPQRGREVRIVSPEDGAELPPGTQGQIEVRTR------------
Mb0276|M.bovis_AF2122/97 NPSTVGPVVKGVTVKILD-ENGNEVPQGAVGRIFVGNAFPFEGYTG---G
Rv0270|M.tuberculosis_H37Rv NPSTVGPVVKGVTVKILD-ENGNEVPQGAVGRIFVGNAFPFEGYTG---G
MLBr_02546|M.leprae_Br4923 NSATVGPVVKGVKVKILD-DSGKEVPRGQVGRIFVGNAFPFEGYTG---G
MAB_4569c|M.abscessus_ATCC_199 KMGSVGRVIPTVSARVVD-DNMNDVPVGEVGEIVYRAPTLMQGYWNNPEA
: .:** ::: . : * :
Mflv_4362|M.gilvum_PYR-GCK -----TGEWMQTTDVARIDEDGFLWILGRADQAIIRGGFKVMPDDVRSAL
Mvan_1982|M.vanbaalenii_PYR-1 -----RSGWMQTTDLARIDEDGFVWILGRADQAIIRGGFKVMPDDVKNAL
MSMEG_2217|M.smegmatis_MC2_155 -----GSPWMRTTDLARIDADGFLWVLGRADQAIIRGGFKVMPDDVRAAL
MMAR_4025|M.marinum_M -----SAPWVRTTDVARIDADGFVWIVGRADQAIIRGGFKVLPDDVGAAL
MUL_3890|M.ulcerans_Agy99 -----SAPWVRTTDVARIDADGFVWIVGRADQAIIRGGFKVLPDDVRAAL
MAV_1580|M.avium_104 -----DADWLRTTDMARIDADGFVWIVGRADQAIIRGGFKVMPDDVRAAL
TH_3166|M.thermoresistible__bu -----GGEWVRTTDLGRLDSDGFLFVDGRTDDAIIRGGFKISPADIANAL
Mb0276|M.bovis_AF2122/97 GGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLI
Rv0270|M.tuberculosis_H37Rv GGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLI
MLBr_02546|M.leprae_Br4923 GGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLI
MAB_4569c|M.abscessus_ATCC_199 TADAFAGGWFHSGDLVRQDEDGFVWVVDRKKDMIISGGENIYCAEVENAL
. : *: * .:::: .* .: *: ** :: :: :
Mflv_4362|M.gilvum_PYR-GCK ESHAAVAGAAVVGRPDPRLGETPVALVELRPGATASPEELSAYLQTRLAR
Mvan_1982|M.vanbaalenii_PYR-1 ESHPAVAGASVVGRPDPRLGETPVALVQLRPGMSAEPDELLNYLQKRLAR
MSMEG_2217|M.smegmatis_MC2_155 ESHPAVLGASVIGVADERLGETPVAMVELRG--PATPDELAGYLQGRLAR
MMAR_4025|M.marinum_M ESHPAVAAAAVVGRSDQRLGQTPVAMVELRGSADIGGAELVEYLRTRLSG
MUL_3890|M.ulcerans_Agy99 ESHPAVAAAAVVGRSDQRLGQTPVAMVELRGSADIGGAELVEYLRTRLSG
MAV_1580|M.avium_104 ESHPAVAGAAVVARPDPRLGETPVAMVELRAPSTT--DALVEHLRERLAR
TH_3166|M.thermoresistible__bu RSHPAVRDAGVTGLPDPRLGAVPVAAVELAGGAQAEPDELLDFLRQRLTR
Mb0276|M.bovis_AF2122/97 SGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLAR
Rv0270|M.tuberculosis_H37Rv SGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLAR
MLBr_02546|M.leprae_Br4923 SGHPEVVEATAIGVDDKEWGARLRAFVVKKQDATIDEDAIKAYVRDHLAR
MAB_4569c|M.abscessus_ATCC_199 AEHEQIAEVAVIGRPHEKWGEVPVAVAAIHG-AALTLAELDGFLTARLAR
* : . . . . . * * . : .: :*:
Mflv_4362|M.gilvum_PYR-GCK YEIPTALILTDAIPRTPSGKPDLTAVRARLAQP---------
Mvan_1982|M.vanbaalenii_PYR-1 YEIPGELVITDAIPRTASGKPDLTAVRSHFAQS---------
MSMEG_2217|M.smegmatis_MC2_155 YEIPTRITIVDAIPRTPSGKADLRAVRDHLESGG--------
MMAR_4025|M.marinum_M YEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRT-DHGG
MUL_3890|M.ulcerans_Agy99 YEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRT-DHGG
MAV_1580|M.avium_104 YEIPTEIAIVDALPRTPSGKADLAAVRGYFAERPTVLRDHAR
TH_3166|M.thermoresistible__bu YQVPARLLVLDELPRTPSLKVSQPALRELFEQEPT-------
Mb0276|M.bovis_AF2122/97 YKVPREVIFLDELPRNPTGKVLKRELRKL-------------
Rv0270|M.tuberculosis_H37Rv YKVPREVIFLDELPRNPTGKVLKRELRKL-------------
MLBr_02546|M.leprae_Br4923 YKVPREVIFLEELPRNPTGKVLKRELRDFEVH----------
MAB_4569c|M.abscessus_ATCC_199 YKHPKDLVIVDALPRNPSGKVLKTELRQRFGIAD--------
*: * : . :**..: * :*