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M. thermoresistible (build 8) TH_3466 (-)

annotation: Alcohol dehydrogenase GroES domain protein
coordinates: 340374 - 341213
length: 280

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3466--100% (280)Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)TH_2558-1e-3635.07% (288) PUTATIVE putative aryl-alcohol dehydrogenase
M. thermoresistible (build 8)TH_4627-7e-3532.28% (285) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0167cadhE11e-11873.84% (279) putative zinc-type alcohol dehydrogenase (e subunit) adhE
M. gilvum PYR-GCKMflv_4588-1e-3634.74% (285) alcohol dehydrogenase
M. tuberculosis H37RvRv0162cadhE11e-11873.84% (279) zinc-type alcohol dehydrogenase E subunit
M. leprae Br4923MLBr_01784adhE21e-3432.63% (285) putative alcohol dehydrogenase (Zn dependent)
M. abscessus ATCC 19977MAB_0983c-8e-6748.91% (276) zinc-containing alcohol dehydrogenase
M. marinum MMMAR_0405adhE1e-11673.82% (275) zinc-type alcohol dehydrogenase (E subunit) AdhE
M. avium 104MAV_5022-1e-11977.09% (275) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_0127-1e-12378.55% (275) oxidoreductase, zinc-binding dehydrogenase family protein
M. ulcerans Agy99MUL_1292adhE21e-3331.23% (285) zinc-dependent alcohol dehydrogenase AdhE2
M. vanbaalenii PYR-1Mvan_3767-5e-3431.93% (285) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3466|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0127|M.smegmatis_MC2_155      -------------MKIRGAVLERIGAPRPYAESRPLTISELDLADPGPDE
Mb0167c|M.bovis_AF2122/97           -MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELHLDPPDRGE
Rv0162c|M.tuberculosis_H37Rv        -MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELHLDPPDRGE
MMAR_0405|M.marinum_M               MELGLQPWLYSNMIHIRGAVLERIGSPRPYAQSRPISVVDLDLDPPGDDE
MAV_5022|M.avium_104                -------------------MLQRIGAPRPYARSRPISITDVELAPPGRDE
MAB_0983c|M.abscessus_ATCC_199      -------------MRIRSAVLHAAPIERPYRDTHPLKVIELELDPPGPGE
Mflv_4588|M.gilvum_PYR-GCK          -------------MKTRAAVLWGLG--------EKWEVDEIELDPPGVDE
MLBr_01784|M.leprae_Br4923          -------------------MSQTVRGVISRKKDEPVELVDIVIPDPGPGE
MUL_1292|M.ulcerans_Agy99           -------------------MSQTVRGVISRKKGEPVELVDIVVPDPGPGE
Mvan_3767|M.vanbaalenii_PYR-1       -------------------MTQTVRGVISRTKGQPVEVVEIVIPDPGPGE
                                                                                      

TH_3466|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0127|M.smegmatis_MC2_155      LLVRIESAGLCHSDLSVVDGNRVRPVPMLLGHEAAGVVETPG---ADLET
Mb0167c|M.bovis_AF2122/97           VLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAV
Rv0162c|M.tuberculosis_H37Rv        VLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAV
MMAR_0405|M.marinum_M               VLVRIEAAGVCHSDLSVVDGNRVRPVPMLLGHEAAGIVERVGDRVDDLAV
MAV_5022|M.avium_104                VLVRIEAAGICHSDLSVVDGNRVRPVPMLLGHEAAGIVERVGPGVADLAV
MAB_0983c|M.abscessus_ATCC_199      VLVRIEAAGLCHSDLSVVDGNRIRPVPMALGHEAAGVIAAVGPGVRDVSP
Mflv_4588|M.gilvum_PYR-GCK          VLVQLTASGLCHSDEHLVTGDLPFPLPVVGGHEGAGTVVEVGAGVEDLAV
MLBr_01784|M.leprae_Br4923          AVVDVTACGVCHTDLTYREGGINDRYPFLLGHEAAGTVEVVGPGVTAVEP
MUL_1292|M.ulcerans_Agy99           AVVDISACGVCHTDLTYREGGINDEYPFLLGHEAAGTVEAVGPGVTNVEP
Mvan_3767|M.vanbaalenii_PYR-1       VVVDIQACGVCHTDLHYREGGINDEFPFLLGHEAAGTVESVGAGVTNVAP
                                                                                      

TH_3466|M.thermoresistible__bu      ---VVMTFLPRCGHCPACATDGLTPCEPGSAANTAGTLLSGAIRLT-RDG
MSMEG_0127|M.smegmatis_MC2_155      GQRVVMTFLPRCGSCPACGTDGLTPCGPGSVANGAGTLMNGDIRLR-RDG
Mb0167c|M.bovis_AF2122/97           GQRVVLVFLPRCGQCAACATDGRTPCEPGSAANKAGTLLGGGIRLS-RGG
Rv0162c|M.tuberculosis_H37Rv        GQRVVLVFLPRCGQCAACATDGRTPCEPGSAANKAGTLLGGGIRLS-RGG
MMAR_0405|M.marinum_M               GQRVVLVFLPRCGHCPSCATEGITPCAPGSATNAAGTLLGGGIRIS-RSG
MAV_5022|M.avium_104                GARVVLVFLPRCGRCAACATEGLTPCEPGSAANGAGTLLGGDIRLS-RAG
MAB_0983c|M.abscessus_ATCC_199      GDHVVLVYVPSCGACRYCSSGRPALCPDAAAANGRGDLIRGGTRLHDLDG
Mflv_4588|M.gilvum_PYR-GCK          GDSVILTFLPSCGHCSYCARGMGNLCDMG-AAIMMGPQIDGTYRFH-ARG
MLBr_01784|M.leprae_Br4923          GDFVILNWRAVCGQCRACKRGRPSYCFDTFNAQQKMTLIDG---------
MUL_1292|M.ulcerans_Agy99           GDFVILNWRAVCGQCRACKRGRPSYCFDTFNAEQKMTLTDG---------
Mvan_3767|M.vanbaalenii_PYR-1       GDFVVLNWRAVCGQCRACKRGRPHLCFDTFNAEQKMTLTDG---------
                                       *:: : . ** *  *       *     :        *         

TH_3466|M.thermoresistible__bu      QPVHHHLGISGFASHAVVDRRSVVPVDSDVPPSVAALLGCAVLTGGGAVL
MSMEG_0127|M.smegmatis_MC2_155      EPVFHHLGVSGFATHAVVDRRSIVPVPDDVPATVAALLGCAVLTGGGAVL
Mb0167c|M.bovis_AF2122/97           RPVYHHLGVSGFATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGAVL
Rv0162c|M.tuberculosis_H37Rv        RPVYHHLGVSGFATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGAVL
MMAR_0405|M.marinum_M               QPIYHHLGVSGFATHAVVNRASAVAVPDEVPPQVAALLGCAVLTGGGAVL
MAV_5022|M.avium_104                RPVYHHLGVSGFATHAVVNRASAVEVPPDVPAEVAALLGCAVLTGGGAVL
MAB_0983c|M.abscessus_ATCC_199      TEVRHHLGVSGFADHAVVDRNSVVVIDENVPLDTAALFGCAMLTGFGAVT
Mflv_4588|M.gilvum_PYR-GCK          EDVGQMCLLGTFSEYTVVPKASLVKVDHGTPLDKAALIGCGVTTGYGSAV
MLBr_01784|M.leprae_Br4923          TELTPALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAI
MUL_1292|M.ulcerans_Agy99           TELTPALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAV
Mvan_3767|M.vanbaalenii_PYR-1       TELTPALGIGAFADKTLVHEGQCTKVDPAADPAAAGLLGCGVMAGLGAAI
                                      :     :. *:  .:*   . . :   .    *.*:**.: :* *:. 

TH_3466|M.thermoresistible__bu      NVGRPRPGQRVIVVGLGGVGLAAVLTALAHPDVRVVGVDQRTDKLHTART
MSMEG_0127|M.smegmatis_MC2_155      NVGRPKPGQTVVVVGLGGVGMAAALTALAHDDVRVVGVDQLSDKLARAAE
Mb0167c|M.bovis_AF2122/97           NVGDPQPGQSVAVVGLGGVGMAAVLTALTYTDVRVVAVDQLPEKLSAAKA
Rv0162c|M.tuberculosis_H37Rv        NVGDPQPGQSVAVVGLGGVGMAAVLTALTYTDVRVVAVDQLPEKLSAAKA
MMAR_0405|M.marinum_M               NVGKPVAGQSVAVVGLGGVGMAAVLTALTQDGVAVFGVDQLPQKLSAAEA
MAV_5022|M.avium_104                NVGRPAPGQTVAVVGLGGVGMAALLTALTYDGVPVVAVDQLPEKLAAARR
MAB_0983c|M.abscessus_ATCC_199      HTASVRPGDSVAVLGLGGVGLAVVMSAAAAGAGEVLAIDPVPAKRELALE
Mflv_4588|M.gilvum_PYR-GCK          RTGEVRAGDTVVVIGAGGIGMNAIQGARIAGALTIVAVDPVEFKREQAGG
MLBr_01784|M.leprae_Br4923          NTAAVSRDDTVAVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWART
MUL_1292|M.ulcerans_Agy99           NTGGVTRDDTVAVIGCGGVGDAAIAGAALVGAKKIIAVDTDNTKLEWARA
Mvan_3767|M.vanbaalenii_PYR-1       NTGAVNRDDTVAVIGCGGVGDAAIAGARLVGAKRIIAVDMDNRKLDWARE
                                    ...    .: * *:* **:*  .   *       :..:*    *   *  

TH_3466|M.thermoresistible__bu      LGAHEAYT---------PDQAVDANLKAQVVIEAAGHPDALATAIQLTAP
MSMEG_0127|M.smegmatis_MC2_155      LGVHETFT---------PEQAAD--LRAEVVIEAAGHPAALETAIGLTGP
Mb0167c|M.bovis_AF2122/97           LGAHEIYT---------PQQATAGGVKAAVVVEAVGHPAALHTAIGLTAP
Rv0162c|M.tuberculosis_H37Rv        LGAHEIYT---------PQQATAGGVKAAVVVEAVGHPAALHTAIGLTAP
MMAR_0405|M.marinum_M               LGASATYT---------PQQAAAAGVKADVVIEAAGHPAALETAIGLTAP
MAV_5022|M.avium_104                LGAHQAYT---------PQQAVEARVKAAVVIEAVGHPAALQTAIDLTAP
MAB_0983c|M.abscessus_ATCC_199      LGATSACA---------PDEAPGG---HDWVFEVVGSAAVLEQAYALTGR
Mflv_4588|M.gilvum_PYR-GCK          FGATHAVATIDEAWSLISDITRGKLADVCVLTTDVAEGAYTAEALSLVGK
MLBr_01784|M.leprae_Br4923          FGATHTVN-ALELEVVKTIQDLTSGFGVDVVIDTVGRPETWKQAFYARDL
MUL_1292|M.ulcerans_Agy99           FGATHTVN-ARELDVVETIQDLTGGFGVDVVIDAVGRPETWKQAFYARDL
Mvan_3767|M.vanbaalenii_PYR-1       FGATHTIN-AGELDAVKTIQDLTDGFGADVVIDAVGRPETWKQAFYARDL
                                    :*.              .            :   ..       *      

TH_3466|M.thermoresistible__bu      GGRTITVGLPPPDAR-LTVSPLGLVAEGRSLIGSYLGSAVPARDIPRFVD
MSMEG_0127|M.smegmatis_MC2_155      GGRTITVGLPRPDAR-ITVSPLGFVAEGRSLIGSYLGSAVPSRDIPRFVE
Mb0167c|M.bovis_AF2122/97           GGRTITVGLPPPDVR-ISLSPLDFVTEGRSLIGSYLGSAVPSHDIPRFVS
Rv0162c|M.tuberculosis_H37Rv        GGRTITVGLPPPDVR-ISLSPLDFVTEGRSLIGSYLGSAVPSHDIPRFVS
MMAR_0405|M.marinum_M               GGRTITVGLPPPDAR-ISVAPLGFVAEGRSLIGSYLGSAVPSRDIPRFVS
MAV_5022|M.avium_104                GGRTITVGLPPPDAR-ITVSPLGFVAEGRSLIGSYLGSAVPSRDIPRFVE
MAB_0983c|M.abscessus_ATCC_199      GGGTVSVGLPHPDAR-ISLPALNIVAEGRSILGSYMGSAQPQQDIPAMLA
Mflv_4588|M.gilvum_PYR-GCK          RGRVVITAIGHPEDTSMSGSLLELTLYEKQIRGALYGSSNAAHDIPRLVE
MLBr_01784|M.leprae_Br4923          AGTVVLVGVPTPDMR-LDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVD
MUL_1292|M.ulcerans_Agy99           AGTVVLVGVPTPDMR-LDMPLVDFFSRGGALKSSWYGDCLPERDFPTLID
Mvan_3767|M.vanbaalenii_PYR-1       AGTVVLVGVPTPDMT-LEMPLIDFFSRGGSLKSSWYGDCLPERDFPTLIS
                                     * .: ..:  *:   :  . : :      : .:  *.. . :*:* :: 

TH_3466|M.thermoresistible__bu      LWRSGRLPVEQLVSSTITLDELNEGLDRLADGAAVRQLITLPG--
MSMEG_0127|M.smegmatis_MC2_155      LWRAGRLPVESLVSSTIALDDINAGMDELAEGRAVRQVIDFA---
Mb0167c|M.bovis_AF2122/97           LWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL
Rv0162c|M.tuberculosis_H37Rv        LWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL
MMAR_0405|M.marinum_M               LWQSGRLPVESLVSATIRLDDLNEAMDHLADGTAVRQIIVF----
MAV_5022|M.avium_104                LWRAGRLPVESLVSSTIRLEDINEAMDHLADGTAVRQLIRFDA--
MAB_0983c|M.abscessus_ATCC_199      LWRAGRLPVEKLKSDDLPLSDINIALDALAEGQAVRQILRPGVSA
Mflv_4588|M.gilvum_PYR-GCK          LYNSGQLKLDELITREYTLDEINEGYDDMRSGRNIRGLIRF----
MLBr_01784|M.leprae_Br4923          LYLQGRLPLGKFVSERIGLGDVEEAFHKIHGGKVLRSVVML----
MUL_1292|M.ulcerans_Agy99           LYLQGRLPLDKFVSEQIGLGGIEEAFEKMHAGKVLRSVVVL----
Mvan_3767|M.vanbaalenii_PYR-1       LYLQGRFPLDKFVSERIGLDQIEDAFDKMHAGEVLRSVVVL----
                                    *:  *:: : .: :    *  :: . . :  *  :* ::