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M. thermoresistible (build 8) TH_2558 (-)

annotation: putative aryl-alcohol dehydrogenase
coordinates: 3098037 - 3099116
length: 360

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2558--100% (360)putative aryl-alcohol dehydrogenase
M. thermoresistible (build 8)TH_2499-2e-4734.81% (362) PUTATIVE Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)TH_4627-9e-4731.96% (363) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0167cadhE12e-4534.28% (353) putative zinc-type alcohol dehydrogenase (e subunit) adhE
M. gilvum PYR-GCKMflv_0725-4e-7544.00% (350) alcohol dehydrogenase
M. tuberculosis H37RvRv0162cadhE12e-4534.28% (353) zinc-type alcohol dehydrogenase E subunit
M. leprae Br4923MLBr_01784adhE22e-4530.58% (363) putative alcohol dehydrogenase (Zn dependent)
M. abscessus ATCC 19977MAB_4388-8e-7846.15% (351) zinc-containing alcohol dehydrogenase
M. marinum MMMAR_0405adhE6e-4732.77% (357) zinc-type alcohol dehydrogenase (E subunit) AdhE
M. avium 104MAV_5022-4e-4934.56% (353) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_4039-2e-7541.55% (361) aryl-alcohol dehydrogenase
M. ulcerans Agy99MUL_1292adhE23e-4531.96% (363) zinc-dependent alcohol dehydrogenase AdhE2
M. vanbaalenii PYR-1Mvan_3767-4e-4733.33% (363) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0167c|M.bovis_AF2122/97           -MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELHLDPPDRGE
Rv0162c|M.tuberculosis_H37Rv        -MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELHLDPPDRGE
MMAR_0405|M.marinum_M               MELGLQPWLYSNMIHIRGAVLERIGSPRPYAQSRPISVVDLDLDPPGDDE
MAV_5022|M.avium_104                -------------------MLQRIGAPRPYARSRPISITDVELAPPGRDE
Mflv_0725|M.gilvum_PYR-GCK          --------------------MPETTAVLSYAPEDPFSVAEVRVDDPRADE
MAB_4388|M.abscessus_ATCC_1997      ---------------------MKVTAALSASPAAPFTLQELELDEPRSDE
MSMEG_4039|M.smegmatis_MC2_155      --------MSHSQIFPTPTDTRTISAALVRATGEPFVITDLALTGPRADE
TH_2558|M.thermoresistible__bu      ---------------------------VLRGETDPYQIEELDLPDPAAHQ
MLBr_01784|M.leprae_Br4923          -------------------MSQTVRGVISRKKDEPVELVDIVIPDPGPGE
MUL_1292|M.ulcerans_Agy99           -------------------MSQTVRGVISRKKGEPVELVDIVVPDPGPGE
Mvan_3767|M.vanbaalenii_PYR-1       -------------------MTQTVRGVISRTKGQPVEVVEIVIPDPGPGE
                                                                      *  : :: :  *   :

Mb0167c|M.bovis_AF2122/97           VLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAV
Rv0162c|M.tuberculosis_H37Rv        VLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAV
MMAR_0405|M.marinum_M               VLVRIEAAGVCHSDLSVVDGNRVRPVPMLLGHEAAGIVERVGDRVDDLAV
MAV_5022|M.avium_104                VLVRIEAAGICHSDLSVVDGNRVRPVPMLLGHEAAGIVERVGPGVADLAV
Mflv_0725|M.gilvum_PYR-GCK          ILVRIEAAGVCHTDLVNRVAGKP-DRPVLLGHEGAGIVERVGDGLQSVKP
MAB_4388|M.abscessus_ATCC_1997      VLVKIHATGLCHTDLT--FKSQV-PIPAVLGHEGAGIVTAVGEAVSGISP
MSMEG_4039|M.smegmatis_MC2_155      ILVRVDAVGICHADTQAQTGALPVPAPMVAGHEGTGIVEEVGSDVQHLKC
TH_2558|M.thermoresistible__bu      ILVRIAGTGHCHTDVLPRAGAGFGTPPIVVGHEGSGVVEAVGAAVDTVAV
MLBr_01784|M.leprae_Br4923          AVVDVTACGVCHTDLTYREGGINDRYPFLLGHEAAGTVEVVGPGVTAVEP
MUL_1292|M.ulcerans_Agy99           AVVDISACGVCHTDLTYREGGINDEYPFLLGHEAAGTVEAVGPGVTNVEP
Mvan_3767|M.vanbaalenii_PYR-1       VVVDIQACGVCHTDLHYREGGINDEFPFLLGHEAAGTVESVGAGVTNVAP
                                     :* : . * **:*            * : ***.:* *  **  :  :  

Mb0167c|M.bovis_AF2122/97           GQRVVLVFLPRCGQCAACATDGRTPCEPGSAAN-KAGTLLGGGIRLS-RG
Rv0162c|M.tuberculosis_H37Rv        GQRVVLVFLPRCGQCAACATDGRTPCEPGSAAN-KAGTLLGGGIRLS-RG
MMAR_0405|M.marinum_M               GQRVVLVFLPRCGHCPSCATEGITPCAPGSATN-AAGTLLGGGIRIS-RS
MAV_5022|M.avium_104                GARVVLVFLPRCGRCAACATEGLTPCEPGSAAN-GAGTLLGGDIRLS-RA
Mflv_0725|M.gilvum_PYR-GCK          GDRVVLSFRS-CGACTNCRARRPAYCRKAVRLN-QFGQRADGTPRVT-VD
MAB_4388|M.abscessus_ATCC_1997      GDHVVLSYRS-CGGCRSCAAGERAYCSRSMRLN-SAGVRADGSPTLS-DN
MSMEG_4039|M.smegmatis_MC2_155      GDRVILTFDS-CGGCDRCRSGIPTQCREFVNRNFTAGARPDGTARLH-LD
TH_2558|M.thermoresistible__bu      GDHVVLSFDS-CGTCGSCLAAHPAYCDTFLERN-LGGPGVDGAAQLTDVD
MLBr_01784|M.leprae_Br4923          GDFVILNWRAVCGQCRACKRGRPSYCFDTFNAQ-QKMTLIDGTELTP---
MUL_1292|M.ulcerans_Agy99           GDFVILNWRAVCGQCRACKRGRPSYCFDTFNAE-QKMTLTDGTELTP---
Mvan_3767|M.vanbaalenii_PYR-1       GDFVVLNWRAVCGQCRACKRGRPHLCFDTFNAE-QKMTLTDGTELTP---
                                    *  *:* : . ** *  *       *      :       .*        

Mb0167c|M.bovis_AF2122/97           GRPVY-HHLGVSGFATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGA
Rv0162c|M.tuberculosis_H37Rv        GRPVY-HHLGVSGFATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGA
MMAR_0405|M.marinum_M               GQPIY-HHLGVSGFATHAVVNRASAVAVPDEVPPQVAALLGCAVLTGGGA
MAV_5022|M.avium_104                GRPVY-HHLGVSGFATHAVVNRASAVEVPPDVPAEVAALLGCAVLTGGGA
Mflv_0725|M.gilvum_PYR-GCK          GRSVLDGFFGQSSLAGYALTTQDNTVVVGPDVDPVLAAPLGCGFQTGAGA
MAB_4388|M.abscessus_ATCC_1997      GTPVYGSFFGQSSFAQYALTGADNTVVVDPSIDLAVAAPLGCGFQTGAGA
MSMEG_4039|M.smegmatis_MC2_155      TNAVNGSFFGQSSFATYALATERNAVAVSTQLPPELLAPVGCAIQTGVGT
TH_2558|M.thermoresistible__bu      GQPVAGRWFGQSSFASHAVVDAANAVVVDKDLPLELLGPLGCGVQTGAGA
MLBr_01784|M.leprae_Br4923          -------ALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGA
MUL_1292|M.ulcerans_Agy99           -------ALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGA
Mvan_3767|M.vanbaalenii_PYR-1       -------ALGIGAFADKTLVHEGQCTKVDPAADPAAAGLLGCGVMAGLGA
                                            :* ..:*  .:.   . . *         . :**.. :* *:

Mb0167c|M.bovis_AF2122/97           VLNVGDPQPGQSVAVVGLGGVGMAAVLTALTYTDVRVVAVDQLPEKLSAA
Rv0162c|M.tuberculosis_H37Rv        VLNVGDPQPGQSVAVVGLGGVGMAAVLTALTYTDVRVVAVDQLPEKLSAA
MMAR_0405|M.marinum_M               VLNVGKPVAGQSVAVVGLGGVGMAAVLTALTQDGVAVFGVDQLPQKLSAA
MAV_5022|M.avium_104                VLNVGRPAPGQTVAVVGLGGVGMAALLTALTYDGVPVVAVDQLPEKLAAA
Mflv_0725|M.gilvum_PYR-GCK          VLNLMQPAAGSSVAVFGAGAVGLAGVLAALAVDVETVIVVEPSPQRRALA
MAB_4388|M.abscessus_ATCC_1997      VLNVLSPEPDSRLVVFGAGGVGLAAVMAAKAQGVETIIAVDPVASRRAKA
MSMEG_4039|M.smegmatis_MC2_155      VLDVLAPPPAAPVVVFGAGAVGLSAVMAAAATGHE-VVAVDTKPERLDLA
TH_2558|M.thermoresistible__bu      VLEVLRIGPGESIVITGTGAVGLSAVMAAKVAGASTIIAVDLNTERLALA
MLBr_01784|M.leprae_Br4923          AINTAAVSRDDTVAVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWA
MUL_1292|M.ulcerans_Agy99           AVNTGGVTRDDTVAVIGCGGVGDAAIAGAALVGAKKIIAVDTDNTKLEWA
Mvan_3767|M.vanbaalenii_PYR-1       AINTGAVNRDDTVAVIGCGGVGDAAIAGARLVGAKRIIAVDMDNRKLDWA
                                    .::         :.: * *.** :.:  *       :. *:    :   *

Mb0167c|M.bovis_AF2122/97           KALGAHEIYTP-------QQATAG-GVKAAVVVEAVGHPAALHTAIGLTA
Rv0162c|M.tuberculosis_H37Rv        KALGAHEIYTP-------QQATAG-GVKAAVVVEAVGHPAALHTAIGLTA
MMAR_0405|M.marinum_M               EALGASATYTP-------QQAAAA-GVKADVVIEAAGHPAALETAIGLTA
MAV_5022|M.avium_104                RRLGAHQAYTP-------QQAVEA-RVKAAVVIEAVGHPAALQTAIDLTA
Mflv_0725|M.gilvum_PYR-GCK          ESLGVRAALSPDDHTV-RAIREIT-GGGVDYALDTTGRPEVLASAVAALA
MAB_4388|M.abscessus_ATCC_1997      TELGATQTVDPAMEDV-AAM-----ARGATHALDTTANAGVIATALGLLR
MSMEG_4039|M.smegmatis_MC2_155      RKLGATHVVDPARADVTRAITAIM-PGGAPHVFESSGAPVALIAGVEALA
TH_2558|M.thermoresistible__bu      EEFGATHTIVANTGELTEQIRAIV-PGGTHYGLDTTGLPAVIAAALEAVA
MLBr_01784|M.leprae_Br4923          RTFGATHTVNALELEVVKTIQDLTSGFGVDVVIDTVGRPETWKQAFYARD
MUL_1292|M.ulcerans_Agy99           RAFGATHTVNARELDVVETIQDLTGGFGVDVVIDAVGRPETWKQAFYARD
Mvan_3767|M.vanbaalenii_PYR-1       REFGATHTINAGELDAVKTIQDLTDGFGADVVIDAVGRPETWKQAFYARD
                                      :*.     .                 .   .:: . . .   ..    

Mb0167c|M.bovis_AF2122/97           PGGRTITVGLPPPDVRISLSPLDFVTEGRSLIGSYLGSAVPSHDIPRFVS
Rv0162c|M.tuberculosis_H37Rv        PGGRTITVGLPPPDVRISLSPLDFVTEGRSLIGSYLGSAVPSHDIPRFVS
MMAR_0405|M.marinum_M               PGGRTITVGLPPPDARISVAPLGFVAEGRSLIGSYLGSAVPSRDIPRFVS
MAV_5022|M.avium_104                PGGRTITVGLPPPDARITVSPLGFVAEGRSLIGSYLGSAVPSRDIPRFVE
Mflv_0725|M.gilvum_PYR-GCK          VGGTAVAVGLGTG--VPAIDLADLVLRGKTVHGCLEGDSIPSVFIPELLA
MAB_4388|M.abscessus_ATCC_1997      QRGVLVLVGLGAQ--PGPIDLNDLMLGGKVIRGCIEGDANPQEFIPELLQ
MSMEG_4039|M.smegmatis_MC2_155      PGGTIAVVGTSAAGVTVGIDVVDLVNKSKHIVGVVEGASRPHESIPRLVK
TH_2558|M.thermoresistible__bu      VRGTMGLVGVQQG--ELAIGPLALTIG-RTITGILEGDAEPRTFIPRLIE
MLBr_01784|M.leprae_Br4923          LAGTVVLVGVPTPDMRLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVD
MUL_1292|M.ulcerans_Agy99           LAGTVVLVGVPTPDMRLDMPLVDFFSRGGALKSSWYGDCLPERDFPTLID
Mvan_3767|M.vanbaalenii_PYR-1       LAGTVVLVGVPTPDMTLEMPLIDFFSRGGSLKSSWYGDCLPERDFPTLIS
                                      *    **         :    :      : .   * . *   :* :: 

Mb0167c|M.bovis_AF2122/97           LWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL
Rv0162c|M.tuberculosis_H37Rv        LWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL
MMAR_0405|M.marinum_M               LWQSGRLPVESLVSATIRLDDLNEAMDHLADGTAVRQIIVF----
MAV_5022|M.avium_104                LWRAGRLPVESLVSSTIRLEDINEAMDHLADGTAVRQLIRFDA--
Mflv_0725|M.gilvum_PYR-GCK          LHARGRFPIERLVT-EFSHRDVTEALAAQHAGDVVKPVLTWP---
MAB_4388|M.abscessus_ATCC_1997      MHARGHFPIESLIT-TYPAADIEQAVADARSGAAIKPVLLW----
MSMEG_4039|M.smegmatis_MC2_155      MIEDGALPVHEIVT-TFPLEDIAAAIDAAKSGRVVKPVLLPH---
TH_2558|M.thermoresistible__bu      LWRAGRFPFDRMIE-TFPLSEINTAEQRALAGEIIKPVLIPGA--
MLBr_01784|M.leprae_Br4923          LYLQGRLPLGKFVSERIGLGDVEEAFHKIHGGKVLRSVVML----
MUL_1292|M.ulcerans_Agy99           LYLQGRLPLDKFVSEQIGLGGIEEAFEKMHAGKVLRSVVVL----
Mvan_3767|M.vanbaalenii_PYR-1       LYLQGRFPLDKFVSERIGLDQIEDAFDKMHAGEVLRSVVVL----
                                    :   * :*.  ::        :  *      *  :: ::