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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3397 | - | - | 100% (312) | putative diguanylate cyclase |
| M. thermoresistible (build 8) | TH_0811 | - | 1e-08 | 33.33% (153) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_3406 | - | 5e-08 | 21.59% (264) | PUTATIVE diguanylate cyclase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1389c | - | 8e-09 | 32.03% (153) | hypothetical protein Mb1389c |
| M. gilvum PYR-GCK | Mflv_2073 | - | 7e-20 | 39.49% (157) | diguanylate cyclase/phosphodiesterase |
| M. tuberculosis H37Rv | Rv1354c | - | 8e-09 | 32.03% (153) | hypothetical protein Rv1354c |
| M. leprae Br4923 | MLBr_00397 | - | 8e-14 | 33.76% (157) | putative transporter protein |
| M. abscessus ATCC 19977 | MAB_3940c | - | 6e-18 | 29.60% (321) | hypothetical protein MAB_3940c |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2738 | - | 5e-40 | 34.64% (306) | diguanylate cyclase |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 3e-09 | 32.10% (162) | sensory box/response regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0374 | - | 8e-89 | 52.27% (308) | diguanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK MHGGAVSNGRIRPLAGPWLWIPIGLTVALAVLLAVDDSRGLGVRTVDNAI
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 --------------------------------------------------
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK TLTLSSYATLCAWLAARDARGRARKSWTLMAGALGAYALGDLTWLVRESA
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 --------------------------------------------------
TH_3397|M.thermoresistible__bu ----------------------------------------LDAMLRRRML
Mvan_0374|M.vanbaalenii_PYR-1 -------------------------MVLTARSDADPPGRHLDERLRRKML
Mb1389c|M.bovis_AF2122/97 ---------------------------MCNDTATPQLEELVTTVANQLMT
Rv1354c|M.tuberculosis_H37Rv ---------------------------MCNDTATPQLEELVTTVANQLMT
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------MSESLDVLVTSVATQLMA
MAV_2738|M.avium_104 ------------------------------MRLRADAGSVFYRTQQARML
Mflv_2073|M.gilvum_PYR-GCK MHTQPFPSPADFFYLVFTILAVLSVLTMARYGAGSTRHSKLRVALDGVTI
MAB_3940c|M.abscessus_ATCC_199 ---------MIVSYIRSTAWMGFLRQWWTEPVPTGWLRGFLHARKLDRTV
MLBr_00397|M.leprae_Br4923 --------------------------------------------MDHTTK
TH_3397|M.thermoresistible__bu VAYLLILLVLYALAVGVAVAVDTPPSDARGEVLAVLLCVVGVAAATPRPL
Mvan_0374|M.vanbaalenii_PYR-1 LINLGLLSAVYALAVVQALVLDSPRSDARGEIVAVALTVAGLLVSLRAPL
Mb1389c|M.bovis_AF2122/97 VDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNI
Rv1354c|M.tuberculosis_H37Rv VDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNI
MSMEG_2196|M.smegmatis_MC2_155 VEAATSVSVSQQVLAELVSFFDVDVSFLRHNDHRAHATRLVAEWPPRPVD
MAV_2738|M.avium_104 RIFLGATTFLYAYGVVFTLFPIRAGLTLSNPAGGIVAVGLGLGALAWLAA
Mflv_2073|M.gilvum_PYR-GCK ALSAPLLAWIVALKDVYADNLGNPASLVIATAYPVLDIVALGVTVSVLVR
MAB_3940c|M.abscessus_ATCC_199 RNLIGGYALIFAAICIAVQFSDTGPRSMIGRVIVGLCAVGSLGWALRWAV
MLBr_00397|M.leprae_Br4923 CDAEQYFQAIVTSMADGVIVVDIDGR-----------------------I
.
TH_3397|M.thermoresistible__bu RGRRYVTALGCAGAAPTVALLFHDQIAGQSWS-VVPPMFMAVFLHTWHRG
Mvan_0374|M.vanbaalenii_PYR-1 AGWRYVVALFCISAAPILSVLFHELIAAQIWS-VVPLMFVAIFIRTWHSA
Mb1389c|M.bovis_AF2122/97 PDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVP
Rv1354c|M.tuberculosis_H37Rv PDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVP
MSMEG_2196|M.smegmatis_MC2_155 AATDPIAVVHFADADPVFAMAEHLKEPAVFRPEPLYDDYQRTIEAGRHIP
MAV_2738|M.avium_104 RPDKPAPATVTAIVATPIVMAFHRVIIAEFVC-LIAPMFLAMYLRAFYSP
Mflv_2073|M.gilvum_PYR-GCK ADVRYRTVLTLVVAAFALTTIGDVGFAHAVVNGTYTTGSWLDVVWAAGLV
MAB_3940c|M.abscessus_ATCC_199 GPWPSLREAVAFVAFADIGIAVACWQDSDPLAGLVGTVLFTPVGAYVSFF
MLBr_00397|M.leprae_Br4923 ESINPAATRILGLRAHDVVDMKHGHPFCFYDTDNQRVDLEREVMRVVRRE
.
TH_3397|M.thermoresistible__bu ATARVASGAIAVAAATALLIAPAPVPIMWVVLYVVCIPGAGEVYG-----
Mvan_0374|M.vanbaalenii_PYR-1 TTARVVVAGIAAAAVIALLVAPAPIPVVWLAFYAVSVLGAAEVFG-----
Mb1389c|M.bovis_AF2122/97 VTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQ--
Rv1354c|M.tuberculosis_H37Rv VTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQ--
MSMEG_2196|M.smegmatis_MC2_155 ATSMACVPLLSGDVTTGVLGFVKFGDREWLPAELNALKAIASLFAQVQ--
MAV_2738|M.avium_104 RRGAALVAVLAGLSVAALAVAPTPKLSIDYAIFVIAIIGAAESFG-----
Mflv_2073|M.gilvum_PYR-GCK CFAAAGQLARSATMPRRRALTVPPNVSVWLPYVPFMIAGTVGPLVVMSGV
MAB_3940c|M.abscessus_ATCC_199 LANRLLVAHVAWCAPMIIALSSRLFAEGTVGAAMTALVKVTSMLLVVVLI
MLBr_00397|M.leprae_Br4923 VTTVSKVVGIDQHSGQRLWLSVNVSLLAYKAPPHSALVVSFSDISAHH--
:
TH_3397|M.thermoresistible__bu ------------------------LASSALFAMALHDPLTTVWNRAGVEL
Mvan_0374|M.vanbaalenii_PYR-1 ------------------------LGNAALLDAAFRDPLTLVWNRAGVSR
Mb1389c|M.bovis_AF2122/97 ---------------------ARVAAEARLRYLADHDDLTGLHNRRALLQ
Rv1354c|M.tuberculosis_H37Rv ---------------------ARVAAEARLRYLADHDDLTGLHNRRALLQ
MSMEG_2196|M.smegmatis_MC2_155 ---------------------ARIEAEERLRYLADHDHLTGLYNRRALMA
MAV_2738|M.avium_104 ------------------------LLTRALVTAACTDPLTGLLNRAGWEI
Mflv_2073|M.gilvum_PYR-GCK ERFIVPFITAAVCLRQAVAAWENRYLLSLAAERALRDPLTGLANRSLFQD
MAB_3940c|M.abscessus_ATCC_199 PAVIQFG----------------IAVVRWDALAAQRDPLTGLLNRRGIYA
MLBr_00397|M.leprae_Br4923 ------------------------LSIERLTYEATHDCLTGLANRRFAED
* * ** : **
TH_3397|M.thermoresistible__bu KAEQIISRARRRG-----RSVAVIVLDVDDFKTINDRDGHLVGDAVLVEL
Mvan_0374|M.vanbaalenii_PYR-1 RVGRLVRQARRRS-----QEIAVLVFDVDDFKRVNDQRGHAAGDRLLTDL
Mb1389c|M.bovis_AF2122/97 HLDQRLAPGQPG-------PVAALFLDLDRLKAINDYLGHAAGDQFIHVF
Rv1354c|M.tuberculosis_H37Rv HLDQRLAPGQPG-------PVAALFLDLDRLKAINDYLGHAAGDQFIHVF
MSMEG_2196|M.smegmatis_MC2_155 HLEARLAPGQPG-------PVAVMFFDLDRLKAINDYLGHTAGDAFISIL
MAV_2738|M.avium_104 ATADLLSRTRSAT-----ATVTVVALDIDNFKTLNDTEGHVAGDEYLVRC
Mflv_2073|M.gilvum_PYR-GCK RLAHALMLRERDN-----RSVAVISLDLDDFKLVNDSLGHPVADSLLVSA
MAB_3940c|M.abscessus_ATCC_199 EWQRLYGELRREQPLDGDQVTAAAIVDIDRFKSINDRYGHGTGDRVLIDV
MLBr_00397|M.leprae_Br4923 QITKSLQHDERSR------LAAVLLLDLDDFKVINDSLGHDVGDAVLQTV
. :. .*:* :* :** ** ..* :
TH_3397|M.thermoresistible__bu TRRWAARVPASAALGRVGGDEFVVIAS--CDQHRAGELAAELVDGQAVHV
Mvan_0374|M.vanbaalenii_PYR-1 AGRWVAEIPRSSVMGRIGGDEFVLIVGG-FDETQARALADQLTSGLPVPV
Mb1389c|M.bovis_AF2122/97 AQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHV
Rv1354c|M.tuberculosis_H37Rv AQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHV
MSMEG_2196|M.smegmatis_MC2_155 AQRLQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAYRLQSVLRERV
MAV_2738|M.avium_104 AAFWRQVAPAGAVLARFGGDEFAVCIADHHPTSAKADQFVASVRRHTPDT
Mflv_2073|M.gilvum_PYR-GCK GRRIIGCVRTGDTVARVGGDEFALLLEG--DASSPDLIAQRVADAFAEPF
MAB_3940c|M.abscessus_ATCC_199 AHALTCGTTGTSVVGRSGGEEFLVVTVCPASAVAEFATRLRQAVTASMPA
MLBr_00397|M.leprae_Br4923 AQRLRSAVRPDDVVARLGGDEFIVLLRGPLSDMNANDVAKRLHTTLSESL
:.* **:** :
TH_3397|M.thermoresistible__bu SYG-----------VAVGPA--DKCDFATLFAAADADLYRRKRSRKAVPG
Mvan_0374|M.vanbaalenii_PYR-1 TYG-----------VAAGPP--GHRALDTLFAAADRDLYERKRLRKA---
Mb1389c|M.bovis_AF2122/97 AIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALAAKHAGGDSVA
Rv1354c|M.tuberculosis_H37Rv AIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALAAKHAGGDSVA
MSMEG_2196|M.smegmatis_MC2_155 TVDGEMLTRTVSIGIAQGIP--GKDSTSDVLNRADHAVLTAKGSGGNRVA
MAV_2738|M.avium_104 SVG-----------TASGAG--ASADIASLYAAADAELYSAKRRRRDPGL
Mflv_2073|M.gilvum_PYR-GCK IVDGHQILMHPSIGVAVTPPDEAEVSAQTLITRADMAMYTAKKSRSSRVY
MAB_3940c|M.abscessus_ATCC_199 GIAVTASVGVAAQAVSRVVSATSQEAIEVLTACADRAMYEAKHDGGDQSR
MLBr_00397|M.leprae_Br4923 VVDQLTVPIGASVGILEVRPD-DRRRAADILRDADSAMYAAKNKKQCAVT
: ** *
TH_3397|M.thermoresistible__bu R-------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 IFTADMSVSG-----------------ELRNDIELHLRRGIESDALRLVY
Rv1354c|M.tuberculosis_H37Rv IFTADMSVSG-----------------ELRNDIELHLRRGIESDALRLVY
MSMEG_2196|M.smegmatis_MC2_155 VFSDAMAMEI-----------------DFRNDIELHLQSVIEGGALVLHY
MAV_2738|M.avium_104 RPARG---------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK TFDADMTLPGPDADSMTESPDRKPGAGAAKVQLLGELRRAIDAAELEMVY
MAB_3940c|M.abscessus_ATCC_199 ILHADDDSEG---------------------------RYLWRSGA-----
MLBr_00397|M.leprae_Br4923 PQQLVPFVALIALFVFFTAAAGAKFYAPSNLLVILQQTVVLAIVGYGMTF
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 LPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDR--
Rv1354c|M.tuberculosis_H37Rv LPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDR--
MSMEG_2196|M.smegmatis_MC2_155 LPEIDMRTGEVLAAEALVRWEHPTRGLLSPDSFIGVAESINLAGELGR--
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK QPKVALRTGRIIGVEALLRWPHPRLGLLYPGAFMSLVRQHGLMRPVSD--
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 VIMAGSVDLSVGSIVALTGVTAALVAAQNQFAAIVTALLVGLAAGMVNGI
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 -WVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQH
Rv1354c|M.tuberculosis_H37Rv -WVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQH
MSMEG_2196|M.smegmatis_MC2_155 -WVLRTACAEFSRWRANGVGRNIVLRINVSPVQLVTDGFVESVAGIMKEF
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK -LVVDKVLDAATAWKAEGVR--IPVAVNLFAPTLRDAQLPDRLLGALEKR
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 VFAYGKIPSFVSTLGMLQVCRGITLMISDSSAKPMPFHGILGAMGAMPWI
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 GLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAIS
Rv1354c|M.tuberculosis_H37Rv GLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAIS
MSMEG_2196|M.smegmatis_MC2_155 GLPRGSVCLEITESVVVQDIETTRTTLTGLHNVGVQVAIDDFGTGYSVLS
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK GLTADMLTVEITEDLVVDDLGTVTDVLQQLRHCGIRVAIDDFGSGYSALS
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 LIVCLFVTILAGILFQFTMFGRWVKAIGGNERVATLAGVPTRGIKVAIFA
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 LLQTLP-IDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGV
Rv1354c|M.tuberculosis_H37Rv LLQTLP-IDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGV
MSMEG_2196|M.smegmatis_MC2_155 LLKSLP-VDTLKIDRSFVAELGSNPGDLPIVRAVIALAGAFGLQLVAEGV
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK YLRDLP-IDEIKLDRYFVAPVTEDPRAAAVVSAVIDLAHDLGIVVVAEGV
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 ICGLTAGLGGIVLASRLGAGTPTAATGFEIDVIAAVVIGGTPLTGGLGRL
TH_3397|M.thermoresistible__bu --------------------------------------------------
Mvan_0374|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 ETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDP
Rv1354c|M.tuberculosis_H37Rv ETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDP
MSMEG_2196|M.smegmatis_MC2_155 ETERAALTLLRHGCYRAQGFLLSKPILGSEMQTLLAKGRVPVHFSAAPRM
MAV_2738|M.avium_104 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK EEPVTAHWLRGKQCDIAQGYYFGRPTDRAHLPGLVEAAALPRLDVVAD--
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 SGTLIGAIIISMLSNGMVFMGVGNAASQIIKGIMLAAAVFVFLQRRKIGI
TH_3397|M.thermoresistible__bu ---
Mvan_0374|M.vanbaalenii_PYR-1 ---
Mb1389c|M.bovis_AF2122/97 ALS
Rv1354c|M.tuberculosis_H37Rv ALS
MSMEG_2196|M.smegmatis_MC2_155 ---
MAV_2738|M.avium_104 ---
Mflv_2073|M.gilvum_PYR-GCK ---
MAB_3940c|M.abscessus_ATCC_199 ---
MLBr_00397|M.leprae_Br4923 IK-