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VHGGAVSNGRIRPLAGPWLWIPIGLTVALAVLLAVDDSRGLGVRTVDNAITLTLSSYATLCAWLAARDAR GRARKSWTLMAGALGAYALGDLTWLVRESAMHTQPFPSPADFFYLVFTILAVLSVLTMARYGAGSTRHSK LRVALDGVTIALSAPLLAWIVALKDVYADNLGNPASLVIATAYPVLDIVALGVTVSVLVRADVRYRTVLT LVVAAFALTTIGDVGFAHAVVNGTYTTGSWLDVVWAAGLVCFAAAGQLARSATMPRRRALTVPPNVSVWL PYVPFMIAGTVGPLVVMSGVERFIVPFITAAVCLRQAVAAWENRYLLSLAAERALRDPLTGLANRSLFQD RLAHALMLRERDNRSVAVISLDLDDFKLVNDSLGHPVADSLLVSAGRRIIGCVRTGDTVARVGGDEFALL LEGDASSPDLIAQRVADAFAEPFIVDGHQILMHPSIGVAVTPPDEAEVSAQTLITRADMAMYTAKKSRSS RVYTFDADMTLPGPDADSMTESPDRKPGAGAAKVQLLGELRRAIDAAELEMVYQPKVALRTGRIIGVEAL LRWPHPRLGLLYPGAFMSLVRQHGLMRPVSDLVVDKVLDAATAWKAEGVRIPVAVNLFAPTLRDAQLPDR LLGALEKRGLTADMLTVEITEDLVVDDLGTVTDVLQQLRHCGIRVAIDDFGSGYSALSYLRDLPIDEIKL DRYFVAPVTEDPRAAAVVSAVIDLAHDLGIVVVAEGVEEPVTAHWLRGKQCDIAQGYYFGRPTDRAHLPG LVEAAALPRLDVVAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2073 | - | - | 100% (785) | diguanylate cyclase/phosphodiesterase |
| M. gilvum PYR-GCK | Mflv_3478 | - | 0.0 | 54.86% (782) | diguanylate cyclase/phosphodiesterase |
| M. gilvum PYR-GCK | Mflv_4444 | - | 1e-68 | 28.84% (742) | diguanylate cyclase/phosphodiesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1389c | - | 7e-61 | 34.06% (461) | hypothetical protein Mb1389c |
| M. tuberculosis H37Rv | Rv1354c | - | 7e-61 | 34.06% (461) | hypothetical protein Rv1354c |
| M. leprae Br4923 | MLBr_01750 | - | 7e-55 | 31.71% (473) | hypothetical protein MLBr_01750 |
| M. abscessus ATCC 19977 | MAB_1839 | - | 2e-12 | 26.51% (347) | diguanylate cyclase/phosphodiesterase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1410 | - | 8e-77 | 30.38% (757) | cyclic diguanylate phosphodiesterase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 3e-54 | 32.20% (472) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_0811 | - | 1e-55 | 32.56% (473) | sensory box/response regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4640 | - | 0.0 | 60.41% (773) | diguanylate cyclase/phosphodiesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2073|M.gilvum_PYR-GCK MHGGAVSNGRIRPLAGPWLWIPIG--LTVALAVLLAVDDSR--GLGVRTV
Mvan_4640|M.vanbaalenii_PYR-1 -----MSGGRPR-LLGSCIAVPVG--LTVALAVVLAVGGD---GAWVPVL
MAV_1410|M.avium_104 MKRWAVNPWRRSGVPARVGWLLAGGYGTAALLVLLSSVRGWRGPYGTRPV
MSMEG_2196|M.smegmatis_MC2_155 ---------------------------------------------MSESL
TH_0811|M.thermoresistible__bu ---------------------------------------------VSTEL
MLBr_01750|M.leprae_Br4923 ---------------------------------------------MTRSL
Mb1389c|M.bovis_AF2122/97 ----------------------------------------MCNDTATPQL
Rv1354c|M.tuberculosis_H37Rv ----------------------------------------MCNDTATPQL
MAB_1839|M.abscessus_ATCC_1997 ----------------------MVTTYPGRNGFGSESNRCSTGAQVYGAN
Mflv_2073|M.gilvum_PYR-GCK DNAITLTLSSYATLCAWLAARDARGRARKSWTLMAGALGAYALGDLTWLV
Mvan_4640|M.vanbaalenii_PYR-1 DDVIIVALSSCATVCAVLAAKSAEGRQRRAWATMAAAMGAWAVADLIWLV
MAV_1410|M.avium_104 DDLVMFVCLAVAAMCAARAARAASGRRRYGWLALTTALLGWAVGEVIWAV
MSMEG_2196|M.smegmatis_MC2_155 DVLVTSVATQLMAVEAATSVSVSQQ-------------------------
TH_0811|M.thermoresistible__bu DLLVTGVATKLMAADAATARDVSRR-------------------------
MLBr_01750|M.leprae_Br4923 DELVTRVASKLMAATAATAVTISEG-------------------------
Mb1389c|M.bovis_AF2122/97 EELVTTVANQLMTVDAATSAEVSQR-------------------------
Rv1354c|M.tuberculosis_H37Rv EELVTTVANQLMTVDAATSAEVSQR-------------------------
MAB_1839|M.abscessus_ATCC_1997 NDILERVGLRRPVSRANAVFITAVG-------------------------
: : . . * :
Mflv_2073|M.gilvum_PYR-GCK RES--AMHTQPFPSPADFFYLVFTILAVLSVLTMARYGAGSTRHSKLRVA
Mvan_4640|M.vanbaalenii_PYR-1 CEY--VLRVEPFPSPADFFYLAFSVLVVPAVLGMAQFDAWSRRQATLRIA
MAV_1410|M.avium_104 YDVRPEFEHAAHPAAAEMVLLLFPVGAMTSLVLLSQLSRHSPR----RLL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LDGVTIALSAPLLAWIVALKDVYADNLGNPASLVIATAYPVLDIVALGVT
Mvan_4640|M.vanbaalenii_PYR-1 LDGVTVALCSFLLAWIFALDRVYEAYRDDKLALGLAFFYPVADMVILAVA
MAV_1410|M.avium_104 LDGLIVATSLFVISWVFVVEAQLREHTGTQVATLAEVFN---DIVLMTTA
MSMEG_2196|M.smegmatis_MC2_155 -------VLAELVSFFDVDVSFLRHNDHRAHATRLVAEWPPRPVDAATDP
TH_0811|M.thermoresistible__bu -------VLADLVRAFELDFSFLRHNDHEIRASKLIAEWPVRENVPDPDP
MLBr_01750|M.leprae_Br4923 -------VLAILVEHFGVDVSFLRHNNHDIHETKLIVEWPPRDYVPDPDP
Mb1389c|M.bovis_AF2122/97 -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
Rv1354c|M.tuberculosis_H37Rv -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
MAB_1839|M.abscessus_ATCC_1997 -------AAAILLAATGMSTIPLLCISLSIPAFLWGIRYARARAVTYGES
:: .
Mflv_2073|M.gilvum_PYR-GCK VSVLVRADVRYRTVLTLVVAAFALTTIGDVGFAHAVVNGTYTTGSWLDVV
Mvan_4640|M.vanbaalenii_PYR-1 VAVLARVDAAHRAVPALLVFGFAVMTLTDSAFAYGVAVDSYRTGSFIDLG
MAV_1410|M.avium_104 ILTLSRARPGDRPSRSLLACGIATISVTDIAMVFYTGIGSYHTDDIGDLA
MSMEG_2196|M.smegmatis_MC2_155 IAVVHFADADP---------VFAMAEHLKEPAVFRPEPLYDDYQRTIEAG
TH_0811|M.thermoresistible__bu IGVVHFEGADP---------VFALAEHAKEIHIFRPEPATDEFQRLIEES
MLBr_01750|M.leprae_Br4923 IGVVYFADADP---------VFAMAEYLKEPAVLRPEPANADYQRRIEEG
Mb1389c|M.bovis_AF2122/97 LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
Rv1354c|M.tuberculosis_H37Rv LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
MAB_1839|M.abscessus_ATCC_1997 VAYVLYCDVAILIG--ICVVTTTGVAFVKLAWLLAVSAYVSLVHGRVAVA
: : : .
Mflv_2073|M.gilvum_PYR-GCK WAAGLVCFAAAGQLARSATMPRRRALTVPPNVSVWLPYVPFMIAGTVGP-
Mvan_4640|M.vanbaalenii_PYR-1 WAVALVAICAAAQLSRENPQFRMPIVLVPSNTALWAPYVPLLLAGTIGP-
MAV_1410|M.avium_104 RVAGVGTLALAGLASVYEQPAPGSPDEIEFRTRLWLPYLPLILAAAVGWG
MSMEG_2196|M.smegmatis_MC2_155 RHIPATSMACVPLLSG------------------------DVTTGVLGFV
TH_0811|M.thermoresistible__bu SGVPASTVAAVPLVSG------------------------EITTGVLGFV
MLBr_01750|M.leprae_Br4923 ASVPAVSLACVPLLSG------------------------EITTGVLGFV
Mb1389c|M.bovis_AF2122/97 RGVPVTSAAAVPLVSG------------------------EITTGLLGFI
Rv1354c|M.tuberculosis_H37Rv RGVPVTSAAAVPLVSG------------------------EITTGLLGFI
MAB_1839|M.abscessus_ATCC_1997 MQSLVTTAGTVLAVVG------------------------AVSRDEYSAA
. : .
Mflv_2073|M.gilvum_PYR-GCK ---LVVMSGVERFIVPFITAAVCLRQAVAAWENRYLLSLAAERALRDPLT
Mvan_4640|M.vanbaalenii_PYR-1 ---PLVMSGLEQLVVPVIVVAVCLRQVVAAWENRQLLRAAAEQALRDPLT
MAV_1410|M.avium_104 HAAGKAIHEPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLT
MSMEG_2196|M.smegmatis_MC2_155 KFGDREWLPAELNALKAIASLFAQVQARIEAEER-----LRYLADHDHLT
TH_0811|M.thermoresistible__bu KYGDRQWHPDELNALKAIASLFAQVQARVEAEER-----LRYLAEHDDLT
MLBr_01750|M.leprae_Br4923 KYGDREWHDDELRALQAIATLFAQLQARIVAEEQ-----LRYLAEHDDLT
Mb1389c|M.bovis_AF2122/97 KFGDRKWHEAELNALMTIATLFAQVQARVAAEAR-----LRYLADHDDLT
Rv1354c|M.tuberculosis_H37Rv KFGDRKWHEAELNALMTIATLFAQVQARVAAEAR-----LRYLADHDDLT
MAB_1839|M.abscessus_ATCC_1997 ALAAAVVTMLLANLFAGLVIYVGKAQFSEHADGR------DRLARHDVLT
. :. . * : : * :* **
Mflv_2073|M.gilvum_PYR-GCK GLANRSLFQDRLAHALMLRERDNRSVAVISLDLDDFKLVNDSLGHPVADS
Mvan_4640|M.vanbaalenii_PYR-1 ELANQRLFYDRLAHALTLSSREGHSVAVVSLDLDDFKLVNDSVGHPEADS
MAV_1410|M.avium_104 GLANRALFVHRLEQAVARRHPDGTPIAVLCLDLDNFKAVNDALGHPAGDE
MSMEG_2196|M.smegmatis_MC2_155 GLYNRRALMAHLEARLAPGQPG--PVAVMFFDLDRLKAINDYLGHTAGDA
TH_0811|M.thermoresistible__bu GLHNRRALLAHLDARLAAGQPG--PVSALYFDLDRLKAVNDYLGHTVGDW
MLBr_01750|M.leprae_Br4923 GLLNRRALIAHLDERLADGQRG--PVTLLFLGLDRLKAVNDYLGHNAGDR
Mb1389c|M.bovis_AF2122/97 GLHNRRALLQHLDQRLAPGQPG--PVAALFLDLDRLKAINDYLGHAAGDQ
Rv1354c|M.tuberculosis_H37Rv GLHNRRALLQHLDQRLAPGQPG--PVAALFLDLDRLKAINDYLGHAAGDQ
MAB_1839|M.abscessus_ATCC_1997 GLLNRRGLQEAYEATVGVPGMH---VTVVVVDLNLFKQINDTFGHHVGDQ
* *: : : :: : ..*: :* :** .** .*
Mflv_2073|M.gilvum_PYR-GCK LLVSAGRRIIGCVRTGDTVARVGGDEFALLLEG--DASSPDLIAQRVADA
Mvan_4640|M.vanbaalenii_PYR-1 LLVRVGQRIADCVRAGDTVARIQGDEFALLLEG--EHDDSKLIAERVVDA
MAV_1410|M.avium_104 LLVRVAERLTAALGDSGTIARLGGDEFAAVIEA--SVDESQAAAHRILEA
MSMEG_2196|M.smegmatis_MC2_155 FISILAQRLQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAYRLQSV
TH_0811|M.thermoresistible__bu FIRVLAERLREGAGPDDLIARLGGDEFVVVPSGPVDADAALELANRLRSR
MLBr_01750|M.leprae_Br4923 LIEVFADRLREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAHRLQTR
Mb1389c|M.bovis_AF2122/97 FIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQ
Rv1354c|M.tuberculosis_H37Rv FIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQ
MAB_1839|M.abscessus_ATCC_1997 VLQRTAHRLRSVVGPDALLARLGGDEFGIVVVG------DAPPHIDYQRA
.: . *: :**. **** :
Mflv_2073|M.gilvum_PYR-GCK FAEPFIVDGHQILMHPSIGVAVTPPDEAEVSAQTLITRADMAMYTAKKSR
Mvan_4640|M.vanbaalenii_PYR-1 FDEPFVLHGEHILLRPSVGVAAASPGEAEVAPETMVMRAETAMNVAKRSR
MAV_1410|M.avium_104 FTGAILIDGIPITVRPSIGFTVCT-GASTCTVDQLLRHADLAMYAAKREG
MSMEG_2196|M.smegmatis_MC2_155 LRERVTVDGEMLTRTVSIGIAQGIPGKDSTS--DVLNRADHAVLTAKGSG
TH_0811|M.thermoresistible__bu LQQQVCVDGEMLTRTASIGVAQGTPGRDTTS--DLLRRADQAVLTAKSAG
MLBr_01750|M.leprae_Br4923 LQKQVVIDGEILTRTVSIGVATGLPGRDTTS--DLLRWADHAALSAK-SD
Mb1389c|M.bovis_AF2122/97 LKDHVAIGGEVLTRTVSIGVASGTPGQHTPS--DLLRRADQAALAAKHAG
Rv1354c|M.tuberculosis_H37Rv LKDHVAIGGEVLTRTVSIGVASGTPGQHTPS--DLLRRADQAALAAKHAG
MAB_1839|M.abscessus_ATCC_1997 VEEALNSASEDVPVSASVGVAAAILPESDRT--TIHTLGPIVTHLLVEAD
. . . : *:*.: : : . .
Mflv_2073|M.gilvum_PYR-GCK SSRVYTFDADMTLP-----------------------------GPDADSM
Mvan_4640|M.vanbaalenii_PYR-1 SSRVHVFDATLESA-----------------------------APDVVAP
MAV_1410|M.avium_104 GQCIRSFMPDLPLPYAFPPPPGSAAPTAVAAVAAGGNGAAPASPPQVATA
MSMEG_2196|M.smegmatis_MC2_155 GNRVAVFSDAMAMEI-----------------------------------
TH_0811|M.thermoresistible__bu GNQITVFTDDMSLEA-----------------------------------
MLBr_01750|M.leprae_Br4923 GSKVVVLDHGISAQH-----------------------------------
Mb1389c|M.bovis_AF2122/97 GDSVAIFTADMSVSG-----------------------------------
Rv1354c|M.tuberculosis_H37Rv GDSVAIFTADMSVSG-----------------------------------
MAB_1839|M.abscessus_ATCC_1997 GAMYGAKKAG----------------------------------------
.
Mflv_2073|M.gilvum_PYR-GCK TESPDRKPGAG---------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 ERGSPQNWPDG---------------------------------------
MAV_1410|M.avium_104 ATSSPSPHDAARRPPRGIRAALGMLAIGVVAFSVSSVAHPDAGHGIFSAT
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 ALYSALNAVAAGLIALRACRIPADRWAWALIAAGMACSAVGDVVYAVWVP
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 DGRSPSVADPEYLAYYPFVYAGLLLLMRARLKRLPIAVQLDSVVCALTLA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AVAAALTAGPLHQAAVHAPKTVWVGLAYPWCDLMLLALAAGMLPILGWRN
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 EIRWALLVAGLVLFAVADGAYLFQTAAGSYRVGSLLDVCWPASSVLIAMA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 SWAPPPATATQARRRFSPYVTPVASTIVALGVIVLAHHSRSAATLAALSL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 VVGAGRFSLTFRDVSLLHSHDRHAMTDELTALPNRRQLVTALQGLPASAS
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK -----------------------------------------AAKVQLLGE
Mvan_4640|M.vanbaalenii_PYR-1 -----------------------------------------AAKVRLLGE
MAV_1410|M.avium_104 PGAGSMPSRANPRRALLLLSLSDFHEITESIGRQFGDELLCHIANRLAGS
MSMEG_2196|M.smegmatis_MC2_155 -----------------------------------------DFRNDIELH
TH_0811|M.thermoresistible__bu -----------------------------------------EFRNDIELH
MLBr_01750|M.leprae_Br4923 -----------------------------------------TLRTEVELH
Mb1389c|M.bovis_AF2122/97 -----------------------------------------ELRNDIELH
Rv1354c|M.tuberculosis_H37Rv -----------------------------------------ELRNDIELH
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LRR-----------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 LRR-----------------------------------------------
MAV_1410|M.avium_104 VRRDDLLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIALDPITV
MSMEG_2196|M.smegmatis_MC2_155 LQS-----------------------------------------------
TH_0811|M.thermoresistible__bu LQS-----------------------------------------------
MLBr_01750|M.leprae_Br4923 LAG-----------------------------------------------
Mb1389c|M.bovis_AF2122/97 LRR-----------------------------------------------
Rv1354c|M.tuberculosis_H37Rv LRR-----------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 QVDGRIAIALCPDHCDHPRELLSRAETALAHAKSARSKIAVYDSAFEAHR
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK -------------AIDAAELEMVYQPKVALRTGRIIGVEALLRWPHPRLG
Mvan_4640|M.vanbaalenii_PYR-1 -------------AIDNGEFHMVYQPIVDLRSGFIVGVEALLRWPHPRLG
MAV_1410|M.avium_104 DNDTNLIEELRTALFDTDELKLHYQPKIDGRDGSIHSVEAVLRWQHPTRG
MSMEG_2196|M.smegmatis_MC2_155 -------------VIEGGALVLHYLPEIDMRTGEVLAAEALVRWEHPTRG
TH_0811|M.thermoresistible__bu -------------VIQDEALLLHFLPEVDMRTGEILATEALVRWHHPTRG
MLBr_01750|M.leprae_Br4923 -------------MID-TDLVLHYLPEVDMSTGKVLGTEALVRWQHPTRG
Mb1389c|M.bovis_AF2122/97 -------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG
Rv1354c|M.tuberculosis_H37Rv -------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LLYPGAFMSLVRQHGLMRPVSDLVVDKVLDAATAWKAE--GVRIPVAVNL
Mvan_4640|M.vanbaalenii_PYR-1 MLSPDAFLPLVRQHGLMRPVTEVVLDNVLDDAARWMAD--GVPMPVAVNL
MAV_1410|M.avium_104 TLLPEEFLPVAERAGLMRKISNRTLSMALQQVRSWREE--GLRLTVAVNL
MSMEG_2196|M.smegmatis_MC2_155 LLSPDSFIGVAESINLAGELGRWVLRTACAEFSRWRANGVGRNIVLRINV
TH_0811|M.thermoresistible__bu LLAPDTFIGVAESVNLAGELGRWVMRTACGEFAKWRAEGIGLDAVLRINV
MLBr_01750|M.leprae_Br4923 LLFPDSFIPVAESINLAGKLGRMVMHSACAEFSRWRSAGVGLDALLRINV
Mb1389c|M.bovis_AF2122/97 LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINV
Rv1354c|M.tuberculosis_H37Rv LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINV
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK FAPTLRDAQLPDRLLGALEKRGLTADMLTVEITEDLVVDDLGTVTDVLQQ
Mvan_4640|M.vanbaalenii_PYR-1 FAPFLRDAQLPSALCQALERRGLPTDLLTVEITEDLVLHDFDVVTGVLGQ
MAV_1410|M.avium_104 STTNLLDIELVGTVERLLANYDLPADALILEITESALVDSVRSRN-TVTA
MSMEG_2196|M.smegmatis_MC2_155 SPVQLVTDGFVESVAGIMKEFGLPRGSVCLEITESVVVQDIETTRTTLTG
TH_0811|M.thermoresistible__bu SPVQLVTDGFVASVADIIDEFGLDGSSVCLEITESVVVQDIKTTRITLEG
MLBr_01750|M.leprae_Br4923 SPVQLVAEGFVDNVAGTLDEFGLDGSMVCLEITENVVVQNIDATRKTLAG
Mb1389c|M.bovis_AF2122/97 SAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLAR
Rv1354c|M.tuberculosis_H37Rv SAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLAR
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LRHCGIRVAIDDFGSGYSALSYLRDLPIDEIKLDRYFVAPVTEDPRAAAV
Mvan_4640|M.vanbaalenii_PYR-1 LREQGIRVAIDDFGSGFSALSYLRELRIDEIKLDRHFIATVASDPRAAAV
MAV_1410|M.avium_104 LQRLGIRISIDDYGTGWSSLARLQEVSVDELKLDRIFVARLAHDARSVAI
MSMEG_2196|M.smegmatis_MC2_155 LHNVGVQVAIDDFGTGYSVLSLLKSLPVDTLKIDRSFVAELGSNPGDLPI
TH_0811|M.thermoresistible__bu LNEVGVQVAIDDFGTGYSVLSHLKTLPVDTLKIDKGFVQDLGNSPGDLAI
MLBr_01750|M.leprae_Br4923 LKEVGVHLAIDDFGTGYSVLTHLKSLPVDTIKIDKSFVAELGSNASDLAI
Mb1389c|M.bovis_AF2122/97 LKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVI
Rv1354c|M.tuberculosis_H37Rv LKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVI
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK VSAVIDLAHDLGIVVVAEGVEEPVTAHWLRGKQCDIAQGYYFGRPTDRAH
Mvan_4640|M.vanbaalenii_PYR-1 VRAVIDLTHDLGSVVVAEGVEEPATAAWLRDRGCDMAQGYYFGKPIEAAD
MAV_1410|M.avium_104 VRSTVALADNLGADLVAEGVENEDTLDALRRYGCNITQGFVHTPPLPPDE
MSMEG_2196|M.smegmatis_MC2_155 VRAVIALAGAFGLQLVAEGVETERAALTLLRHGCYRAQGFLLSKPILGSE
TH_0811|M.thermoresistible__bu VRAIIALAEAFGLQLVAEGVETEAAALTLLRHGCHRAQGFLLSRPIPSNE
MLBr_01750|M.leprae_Br4923 VRAIMALAKEFELEVVAEGVETAVAAQVLLELGCNRAQGFLLSRPVDGAA
Mb1389c|M.bovis_AF2122/97 VRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA
Rv1354c|M.tuberculosis_H37Rv VRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2073|M.gilvum_PYR-GCK LPGLVEAAALPRLDVVAD------------
Mvan_4640|M.vanbaalenii_PYR-1 VPGLVRMAKDPA------------------
MAV_1410|M.avium_104 LRAWIASHAPDPSQSRG-------------
MSMEG_2196|M.smegmatis_MC2_155 MQTLLAKGRVPVHFSAAPRM----------
TH_0811|M.thermoresistible__bu MRELLARGRIPMRFSATP------------
MLBr_01750|M.leprae_Br4923 MESLLAKGVIPMALGTCQSPEPSEHQIHRS
Mb1389c|M.bovis_AF2122/97 MRHMLSARRLPPTCIPATDPALS-------
Rv1354c|M.tuberculosis_H37Rv MRHMLSARRLPPTCIPATDPALS-------
MAB_1839|M.abscessus_ATCC_1997 ------------------------------