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M. thermoresistible (build 8) TH_3206 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 1203553 - 1204128
length: 192

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3206--100% (192)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_1273-3e-3141.52% (171) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)TH_3954-8e-2841.07% (168) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3515c-3e-3040.80% (174) short chain dehydrogenase
M. gilvum PYR-GCKMflv_2071-6e-9082.54% (189) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv3485c-3e-3040.80% (174) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG12e-2237.58% (165) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0598-3e-2438.55% (166) short chain dehydrogenase
M. marinum MMMAR_4968-1e-2739.46% (185) short-chain type dehydrogenase/reductase
M. avium 104MAV_5088fabG5e-3044.64% (168) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_5234-6e-8679.69% (192) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_4042-2e-2840.00% (185) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_4643-8e-8880.63% (191) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2071|M.gilvum_PYR-GCK          ------------------------------------MSNSSE---RVAVI
Mvan_4643|M.vanbaalenii_PYR-1       -----------------------MERVPHHRRKANRMSDSSDRAGREAVV
TH_3206|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5234|M.smegmatis_MC2_155      ------------------------------------MS------QRVAIV
MAB_0598|M.abscessus_ATCC_1997      --------------------------MNLAEAPTEIEGHGLLKGKAVVVT
MAV_5088|M.avium_104                ----------------------------MAES--------LLLGKVAVVT
MLBr_01807|M.leprae_Br4923          -----------------------------------------MTDAAAKVS
Mb3515c|M.bovis_AF2122/97           MNSRAPRNLAVSSPSAQVTGRMVQNGENLFQFRREGPQVQLSFQDRTYLV
Rv3485c|M.tuberculosis_H37Rv        MNSRAPRNLAVSSPSAQVTGRMVQNGENLFQFRREGPQVQLSFQDRTYLV
MMAR_4968|M.marinum_M               --------------------------------------MQLSFQDRTYLV
MUL_4042|M.ulcerans_Agy99           --------------------------------------MQLSFQDRTYLV
                                                                                      

Mflv_2071|M.gilvum_PYR-GCK          VGGASGIGWATAQALAAEGCR-----VTIADRNADGARERASELG-----
Mvan_4643|M.vanbaalenii_PYR-1       VGGASGIGWATATALAAEGCR-----VTIADLNVEGARERAAGLG-----
TH_3206|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5234|M.smegmatis_MC2_155      IGGASGIGWAGAKALAADGCR-----IVVADRDADAAAARAAELG-----
MAB_0598|M.abscessus_ATCC_1997      AAAGTGIGSSTARRALVEGAD-----VVVSDYHERRLTETRDELAALGL-
MAV_5088|M.avium_104                G-AGQGIGREIARALHRHGAR-----VVLADLDGSAARSAAAQIDDSGA-
MLBr_01807|M.leprae_Br4923          AAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAVTHRASVVP-
Mb3515c|M.bovis_AF2122/97           TGGGSGIGKGVAAGLVAAGAA-----VMIVGRNPDKLAAAVKDIEALKT-
Rv3485c|M.tuberculosis_H37Rv        TGGGSGIGKGVAAGLVAAGAA-----VMIVGRNPDKLAAAVKDIEALKT-
MMAR_4968|M.marinum_M               TGGGSGIGKGVAAGLVAAGAS-----VMIVGRNPDKLAGAVQELEALGAN
MUL_4042|M.ulcerans_Agy99           TGGGSGIGKGVAAGLVAAGAS-----VMIVGRNPDKLAGAVQELEALGAN
                                                                                      

Mflv_2071|M.gilvum_PYR-GCK          -SGHRAEAVDVTDEDSVARLFDAI----GPLDIAVNCAG-FSNVGLITDM
Mvan_4643|M.vanbaalenii_PYR-1       -AEHAAAHVDVTDEDSVQRLFEDA----GPIDIAVNCAG-FSNVGLITDM
TH_3206|M.thermoresistible__bu      ----------------VARLFDSV----GELDVAVNCAG-FSNVGLITDM
MSMEG_5234|M.smegmatis_MC2_155      -APHTSGHVDVTDEESVERLFAEVS-TAGPIDIVINCAG-FSNVGLITDM
MAB_0598|M.abscessus_ATCC_1997      -GKVAAVVCDVTSTEAVDALITESVAALGRIDVLVNNAG-LGGETPVADM
MAV_5088|M.avium_104                -N-CTGLACDVTSEEQVGALVAGTVREHGGLDVFVNNAG-ITRDASLKRM
MLBr_01807|M.leprae_Br4923          -DWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAG-ITSDMLIMRM
Mb3515c|M.bovis_AF2122/97           -GAIGYEPADITDEEQTLRVVDAATAWHGRLHGVVHCAGGSQTIGPITQI
Rv3485c|M.tuberculosis_H37Rv        -GAIGYEPADITDEEQTLRVVDAATAWHGRLHGVVHCAGGSQTIGPITQI
MMAR_4968|M.marinum_M               GGAIRYEPTDITNEDETARAVDAVTAWHGRLHGVVHCAGGSETIGPITQV
MUL_4042|M.ulcerans_Agy99           GGAIRYEPTDITNEDETARAVDAVTAWHGRLHGVVHCAGGSENIGPITQV
                                                        .       * :.  :  **       :  :

Mflv_2071|M.gilvum_PYR-GCK          AAEDFRAVIDVCLNGAFIVTKHAGRHLRR---GGSLVQISSLNGRQPAAG
Mvan_4643|M.vanbaalenii_PYR-1       TAADFRAVIDVCLTGAFIVTKHAGRHLRE---GGSLVQISSLNGRQPAAG
TH_3206|M.thermoresistible__bu      PVDQFRSVIDVCLTGAFIVTKHAGRQLRE---GGSLVSISSLNARQAAAG
MSMEG_5234|M.smegmatis_MC2_155      PAEDFRSVIDVCLTGGFIVAKHAGRHLPR---GGVLVSISSLNARQPAAG
MAB_0598|M.abscessus_ATCC_1997      TDDQWDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLGWRAQYG
MAV_5088|M.avium_104                TVADFDAVIAVHLRGTWLGVREAAAVMRERKTG-SIVNMSSLSGKAGNPG
MLBr_01807|M.leprae_Br4923          SEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG-RYIFMGSVVGLSGVPG
Mb3515c|M.bovis_AF2122/97           DSQAWRRTVDLNVNGTMYVLKHAARELVRGG-GGSFVGISSIAASNTHRW
Rv3485c|M.tuberculosis_H37Rv        DSQAWRRTVDLNVNGTMYVLKHAARELVRGG-GGSFVGISSIAASNTHRW
MMAR_4968|M.marinum_M               DSEAWRRTVDLNVNGTMYVLKHAAREMVRGG-GGSFVGISSIAASNTHRW
MUL_4042|M.ulcerans_Agy99           DSEAWRRTVDLNVNGTMYVLKHAAREMVRGG-GGSFVGISSIAASNTHRW
                                        :  .: : : .     : *   : .   *   :  .*: .      

Mflv_2071|M.gilvum_PYR-GCK          MSAYCAAKAGLSMLTQVAALEMGPRGIRVNAVAPGFVHTPLTAAAASVPG
Mvan_4643|M.vanbaalenii_PYR-1       MSAYCAAKAGLSMLTQVAALELGPRGIRVNAVAPGFVHTPLTAAAASVPG
TH_3206|M.thermoresistible__bu      MSAYCAAKAGLSMLTQVAALELAPRGVRVNAVAPGFVHTPLTAPAAAVPG
MSMEG_5234|M.smegmatis_MC2_155      MSAYCAAKAGLSMLTQVAALEMGEAGIRVNAIAPGFVHTPLTAPAAMIPG
MAB_0598|M.abscessus_ATCC_1997      QSHYAAAKAGVMALTRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSS-D
MAV_5088|M.avium_104                QTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQPGLIRTPMTAAMPP--D
MLBr_01807|M.leprae_Br4923          QANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRAMDS--K
Mb3515c|M.bovis_AF2122/97           FGAYGVTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTESPE
Rv3485c|M.tuberculosis_H37Rv        FGAYGVTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTESPE
MMAR_4968|M.marinum_M               FGAYGVTKSAVDHLMQLAADELGASWVRVNSIRPGLIRTDLVAAITESAE
MUL_4042|M.ulcerans_Agy99           FGAYGVTKSAVDHLMQLAADELGASWVRVNSIRPGLIRTDLVAAITESAE
                                       * .:*:.:  : :  * *     : .* : *.:    :         

Mflv_2071|M.gilvum_PYR-GCK          VVEDYVDNTALGRAGTPEDIAAAVVFLCSPGTSWMTGEVLDINGGAHLKR
Mvan_4643|M.vanbaalenii_PYR-1       VVEDYVDNTVLGRAGTAEDIANAVVYLCAPGSSWLTGEVLDINGGAHLKR
TH_3206|M.thermoresistible__bu      VVEEYLENTPLGRAGQPEDVAAAVVFLCSPAASWLTGEVLDLNGGAHLKR
MSMEG_5234|M.smegmatis_MC2_155      VVEEYVENTALGRAGTPEDIAAAVVFVCSPQASWLTGEVLDLNGGAHLRR
MAB_0598|M.abscessus_ATCC_1997      LLDKLSSDEAFGRAAEPWEVAATIAFLASDYSSYLTGEVISVSSQRA---
MAV_5088|M.avium_104                VFAEREAAVPMKRAGEPEEVAGAVVFLASELSSYITGTVLGVGGGRYM--
MLBr_01807|M.leprae_Br4923          YQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
Mb3515c|M.bovis_AF2122/97           LSADYRVCTPLPRVGEVEDVANLAMFLLSDAASWITGQVINVDGGHMLRR
Rv3485c|M.tuberculosis_H37Rv        LSADYRVCTPLPRVGEVEDVANLAMFLLSDAASWITGQVINVDGGHMLRR
MMAR_4968|M.marinum_M               LSSDYAMCTPLPRQGEVEDVANMAMFLLSDAASFVTGQVINVDGGQMLRR
MUL_4042|M.ulcerans_Agy99           LSSDYAMCTPLPRQGEVEDVANMAMFLLSDAASFVTGQVINVDGGQMLRR
                                              : * .   ::*    :: :  :.:::* *: :..      

Mflv_2071|M.gilvum_PYR-GCK          YPDVMGHVMKLMEPAS------
Mvan_4643|M.vanbaalenii_PYR-1       YPDVMGHVMRLVEQSS------
TH_3206|M.thermoresistible__bu      YPDILGHVMKLAEQS-------
MSMEG_5234|M.smegmatis_MC2_155      YPDVLGHVMRLAQG--------
MAB_0598|M.abscessus_ATCC_1997      ----------------------
MAV_5088|M.avium_104                ----------------------
MLBr_01807|M.leprae_Br4923          ----------------------
Mb3515c|M.bovis_AF2122/97           GPDFSPMLEPVFGADGLRGVVG
Rv3485c|M.tuberculosis_H37Rv        GPDFSPMLEPVFGADGLRGVVG
MMAR_4968|M.marinum_M               GPDFSAMLEPVFGRDALRGLV-
MUL_4042|M.ulcerans_Agy99           GPDFSAMLEPVFGRDALRGLV-