For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1273 | - | 100% (556) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | |
| M. thermoresistible (build 8) | TH_1770 | echA13 | 3e-88 | 65.97% (238) | POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) |
| M. thermoresistible (build 8) | TH_2027 | echA13 | 2e-79 | 59.17% (240) | POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3515c | - | 4e-95 | 63.94% (269) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1568 | - | 1e-120 | 86.78% (242) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3485c | - | 4e-95 | 63.94% (269) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-15 | 28.10% (242) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2058 | - | 2e-21 | 32.05% (234) | enoyl-CoA dehydratase/isomerase |
| M. marinum M | MMAR_4972 | echA13_1 | 1e-119 | 85.19% (243) | enoyl-CoA hydratase EchA13_1 |
| M. avium 104 | MAV_0670 | - | 1e-120 | 85.89% (248) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5886 | - | 1e-123 | 88.48% (243) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_4042 | - | 2e-89 | 61.99% (271) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5190 | - | 1e-121 | 87.19% (242) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1568|M.gilvum_PYR-GCK -----MQRVADQD----------QVTYETLDEGRIARIWLNRPDAQNAQS
Mvan_5190|M.vanbaalenii_PYR-1 -----MQRVATLE----------QVTYETLDEGRIARIWLNRPDAQNAQS
MSMEG_5886|M.smegmatis_MC2_155 -MPYLLMRWFDMTGSDGDGGQARQIEYETLDEGRIARIWLNRPQAQNAQS
MMAR_4972|M.marinum_M -----MTLSEQADTSAEGVAPAELVAYETLDEGRIARIWLNRPEAHNAQN
MAV_0670|M.avium_104 -----MTLSEQAGAQPGARPAEELVTYETLDEGRIARIWLNRPDAHNAQS
MLBr_02402|M.leprae_Br4923 ---------------------MKYDTILVDGYQRVGIITLNRPQALNALN
MAB_2058|M.abscessus_ATCC_1997 ---------------------MAEQPIRYEVVDSVAWLTINRPEARNALN
TH_1273|M.thermoresistible__bu ----------MGWSAVAKPDASEQVTYETLDDGRIARIWLNRPEAQNAQS
Mb3515c|M.bovis_AF2122/97 MNSRAPRNLAVSSPSAQVTGRMVQNGENLFQFRREGPQVQLSFQDRTYLV
Rv3485c|M.tuberculosis_H37Rv MNSRAPRNLAVSSPSAQVTGRMVQNGENLFQFRREGPQVQLSFQDRTYLV
MUL_4042|M.ulcerans_Agy99 --------------------------------------MQLSFQDRTYLV
: .
Mflv_1568|M.gilvum_PYR-GCK RTLLVQLDEAFGRAEADDVVRVVILAAR-GKNFSAGHDLGSEAALAERAP
Mvan_5190|M.vanbaalenii_PYR-1 RTLLVQLDEAFGRAEADDEVRVVILAAR-GKNFSAGHDLGSEEAIAERTP
MSMEG_5886|M.smegmatis_MC2_155 RTLLVQLDEAFARAEADDTVRVVILAAR-GKNFSAGHDLGSEEALAEREP
MMAR_4972|M.marinum_M RTLLVQLDEAFGRAEADDTVRVVILAAR-GKNFSAGHDLGSEAALLERKP
MAV_0670|M.avium_104 RGLLVQLDEAFVRAEADDAVRVVILAAR-GKNFSAGHDLGSELALAERQP
MLBr_02402|M.leprae_Br4923 SQMMNEITNAAKELDIDPDVGAILITGS-PKVFAAGADIKEMASLTFTDA
MAB_2058|M.abscessus_ATCC_1997 NAVRTGLIDAVLRFNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQNALKVP
TH_1273|M.thermoresistible__bu RTLLVQLDEAFLRAEADDQVRVVILAAR-GRNFSAGHDLGSEEALLERQP
Mb3515c|M.bovis_AF2122/97 TGGGSGIGKGVAAGLVAAGAAVMIVGRNPDKLAAAVKDIEALKT---GAI
Rv3485c|M.tuberculosis_H37Rv TGGGSGIGKGVAAGLVAAGAAVMIVGRNPDKLAAAVKDIEALKT---GAI
MUL_4042|M.ulcerans_Agy99 TGGGSGIGKGVAAGLVAAGASVMIVGRNPDKLAGAVQELEALGANG-GAI
: .. . .::: : * ::
Mflv_1568|M.gilvum_PYR-GCK GPDQHPTFTCNGATREAVIERTYLQEWHYFFNNTSRWRDLRKITIAQVQG
Mvan_5190|M.vanbaalenii_PYR-1 GPDQHPTFTFNGGTRDAISERTYLQEWHYFFNNTSRWRDLRKITIAQVQG
MSMEG_5886|M.smegmatis_MC2_155 GPGQHPTFAGYGATVAGVAERTYRQEWHFYFENTKRWRDLRKITIAQVQG
MMAR_4972|M.marinum_M GPAQHPTFRSHGGTRDAVMEKLYLQEWHFYFQNTCRWRDLRKITIAQVQG
MAV_0670|M.avium_104 GPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQVQG
MLBr_02402|M.leprae_Br4923 FD-------------------------ADFFSAWGKLAAVRTPMIAAVAG
MAB_2058|M.abscessus_ATCC_1997 P--------------------------KDFAPQFGRNIDVAKPTIAAVNG
TH_1273|M.thermoresistible__bu GPDQHPTFRSHGATATGIAERTYRQEWHFYFENTCRWRDLRKITIAQVQG
Mb3515c|M.bovis_AF2122/97 GYEPADITDEEQTLRVVDAATAWHGRLHGVVHCAGGSQTIGPITQIDSQA
Rv3485c|M.tuberculosis_H37Rv GYEPADITDEEQTLRVVDAATAWHGRLHGVVHCAGGSQTIGPITQIDSQA
MUL_4042|M.ulcerans_Agy99 RYEPTDITNEDETARAVDAVTAWHGRLHGVVHCAGGSENIGPITQVDSEA
: .
Mflv_1568|M.gilvum_PYR-GCK NAISAALMLIWACDLIVASDDAKFSDVVAVRMGMPGVEYYAHP-WEFGAR
Mvan_5190|M.vanbaalenii_PYR-1 NAISAGLMLIWACDLIVASDDARFSDVVAVRMGMPGVEYYAHP-WEFGAR
MSMEG_5886|M.smegmatis_MC2_155 NAISAALMLIWACDLIVAADDARFSDVVAVRMGMPGVEYYAHP-WEFGPR
MMAR_4972|M.marinum_M NAISAALMLIWACDLIVAADNAKFSDVVAVRLGMPGVEYYAHP-WEFGPR
MAV_0670|M.avium_104 NAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPGVEYYAHP-WEFGPR
MLBr_02402|M.leprae_Br4923 YALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKA
MAB_2058|M.abscessus_ATCC_1997 VAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG--RGSPWATPLSWLVPPR
TH_1273|M.thermoresistible__bu NAISAALMLIWACDLIVAADDARFSDVVGVRMGMPGVEYYAHP-WEFGPR
Mb3515c|M.bovis_AF2122/97 WRRTVDLNVNGTMYVLKHAARELVRGGGGSFVGISSIAASNTHRWFGAYG
Rv3485c|M.tuberculosis_H37Rv WRRTVDLNVNGTMYVLKHAARELVRGGGGSFVGISSIAASNTHRWFGAYG
MUL_4042|M.ulcerans_Agy99 WRRTVDLNVNGTMYVLKHAAREMVRGGGGSFVGISSIAASNTHRWFGAYG
: :: : . .
Mflv_1568|M.gilvum_PYR-GCK KAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFARRIAERPTMA
Mvan_5190|M.vanbaalenii_PYR-1 KAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFARRIAERPTMA
MSMEG_5886|M.smegmatis_MC2_155 KAKELLLTGDSIDADEAYRLGMVSKVFGREELEDKTLEFARRIAERPTMA
MMAR_4972|M.marinum_M KAKELLLTGDSLDAEEAYRLGMVSKVFPADELADKTLQFARRIAERPTMA
MAV_0670|M.avium_104 KAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAERPTMA
MLBr_02402|M.leprae_Br4923 KAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSRSA
MAB_2058|M.abscessus_ATCC_1997 VAMQILLTGDPITAARAHQVGLVNEVVPADQLRERTQQLALSIAANAPLS
TH_1273|M.thermoresistible__bu KAKELLLTGDSIDADEAYRMGMVSKVFPRAELEEKTLEFARRIAERPTMA
Mb3515c|M.bovis_AF2122/97 VTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTESPELSADY
Rv3485c|M.tuberculosis_H37Rv VTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTESPELSADY
MUL_4042|M.ulcerans_Agy99 VTKSAVDHLMQLAADELGASWVRVNSIRPGLIRTDLVAAITESAELSSDY
: . : : * . : . . : . .
Mflv_1568|M.gilvum_PYR-GCK ALLVKDSVNAASDAMG----------------------------------
Mvan_5190|M.vanbaalenii_PYR-1 ALLVKDSVNAASDAMG----------------------------------
MSMEG_5886|M.smegmatis_MC2_155 ALLVKDSVNAAADSMG----------------------------------
MMAR_4972|M.marinum_M ALLVKDSVNAASDAMG----------------------------------
MAV_0670|M.avium_104 ALLIKDSVNAASDAMG----------------------------------
MLBr_02402|M.leprae_Br4923 TRMAKEAVNRSFEST-----------------------------------
MAB_2058|M.abscessus_ATCC_1997 VLASKRTVYLSAQHH-----------------------------------
TH_1273|M.thermoresistible__bu ALLIKDSGNAASDAMGXXXQPPVPAGGRLDRLRDLVLIGDVGRMGAHLAA
Mb3515c|M.bovis_AF2122/97 RVCTPLPRVGEVEDVAN---------------------------------
Rv3485c|M.tuberculosis_H37Rv RVCTPLPRVGEVEDVAN---------------------------------
MUL_4042|M.ulcerans_Agy99 AMCTPLPRQGEVEDVAN---------------------------------
. :
Mflv_1568|M.gilvum_PYR-GCK ---------------------------------FTEALRHAFHIHELG--
Mvan_5190|M.vanbaalenii_PYR-1 ---------------------------------FTEALRHAFHIHELG--
MSMEG_5886|M.smegmatis_MC2_155 ---------------------------------FAEALHHAFHIHELG--
MMAR_4972|M.marinum_M ---------------------------------FTEALRHAFHVHELG--
MAV_0670|M.avium_104 ---------------------------------FTEALRHAFHIHELG--
MLBr_02402|M.leprae_Br4923 ---------------------------------LAEGLLHERRLFHST--
MAB_2058|M.abscessus_ATCC_1997 ---------------------------------LAAAYDLADEIWEPV--
TH_1273|M.thermoresistible__bu RPGEFACGGGQPVGIASDDQHLATGRGDRGGHPFADTASAAGHQIRPVGQ
Mb3515c|M.bovis_AF2122/97 ---------------------------------LAMFLLSDAASWITG--
Rv3485c|M.tuberculosis_H37Rv ---------------------------------LAMFLLSDAASWITG--
MUL_4042|M.ulcerans_Agy99 ---------------------------------MAMFLLSDAASFVTG--
::
Mflv_1568|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5190|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5886|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4972|M.marinum_M --------------------------------------------------
MAV_0670|M.avium_104 --------------------------------------------------
MLBr_02402|M.leprae_Br4923 --------------------------------------------------
MAB_2058|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1273|M.thermoresistible__bu RQLHGHPPFRSRDITAGGLXGWHARLHGVVHCAGGSETIGPITQVDSEAW
Mb3515c|M.bovis_AF2122/97 --------------------------------------------------
Rv3485c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4042|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1568|M.gilvum_PYR-GCK -------------HAHWAAYNENRYPVGLPPNVPDWRTLGAPKLSRRDEP
Mvan_5190|M.vanbaalenii_PYR-1 -------------HAHWAAYNENRYPVGLPPNVPDWRTLGAPKLSRRDQP
MSMEG_5886|M.smegmatis_MC2_155 -------------HAHWAAANENRWPVGMPPDVPDWRTLGAPKLARRDTP
MMAR_4972|M.marinum_M -------------HAHWAAHNENRYPIGLPPDVEDWRTAGPTQVARRDTP
MAV_0670|M.avium_104 -------------HAHWAAHNENRYPVGLPPDVEDWRNAKPTRLARRDTP
MLBr_02402|M.leprae_Br4923 -------------FVTDDQSE----------GMAAFIEKRAPQFTHR---
MAB_2058|M.abscessus_ATCC_1997 -------------YLSDDAQE----------GPAAFREKRAPQWKGH---
TH_1273|M.thermoresistible__bu RRTVDLNVNGTMYLIKHAAREMVRGGGGSFVGVSSIASSNTHRWFGAYGP
Mb3515c|M.bovis_AF2122/97 ------------QVINVDGGHMLR-------RGPDFSPMLEPVFGADGLR
Rv3485c|M.tuberculosis_H37Rv ------------QVINVDGGHMLR-------RGPDFSPMLEPVFGADGLR
MUL_4042|M.ulcerans_Agy99 ------------QVINVDGGQMLR-------RGPDFSAMLEPVFGRDALR
.
Mflv_1568|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5190|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5886|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4972|M.marinum_M --------------------------------------------------
MAV_0670|M.avium_104 --------------------------------------------------
MLBr_02402|M.leprae_Br4923 --------------------------------------------------
MAB_2058|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1273|M.thermoresistible__bu SKAALDHLLMVAADELGPSWVRVNGIRPGLTKTDLVAPIMDTPAVVDDYR
Mb3515c|M.bovis_AF2122/97 GVVG----------------------------------------------
Rv3485c|M.tuberculosis_H37Rv GVVG----------------------------------------------
MUL_4042|M.ulcerans_Agy99 GLV-----------------------------------------------
Mflv_1568|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5190|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5886|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4972|M.marinum_M --------------------------------------------------
MAV_0670|M.avium_104 --------------------------------------------------
MLBr_02402|M.leprae_Br4923 --------------------------------------------------
MAB_2058|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1273|M.thermoresistible__bu ACTPLPRFGEVSDIANLAVFLLSDAASWITGQIINVDGGHGLRRGPDMSG
Mb3515c|M.bovis_AF2122/97 --------------------------------------------------
Rv3485c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4042|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1568|M.gilvum_PYR-GCK -----------------
Mvan_5190|M.vanbaalenii_PYR-1 -----------------
MSMEG_5886|M.smegmatis_MC2_155 -----------------
MMAR_4972|M.marinum_M -----------------
MAV_0670|M.avium_104 -----------------
MLBr_02402|M.leprae_Br4923 -----------------
MAB_2058|M.abscessus_ATCC_1997 -----------------
TH_1273|M.thermoresistible__bu MLEPVFGADGLRGVVEG
Mb3515c|M.bovis_AF2122/97 -----------------
Rv3485c|M.tuberculosis_H37Rv -----------------
MUL_4042|M.ulcerans_Agy99 -----------------