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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3138 | - | - | 100% (506) | aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_4137 | - | 3e-61 | 34.44% (453) | PUTATIVE putative [NADP+] succinate-semialdehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_4531 | - | 2e-57 | 34.92% (461) | PUTATIVE putative betaine aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1760 | gabD2 | 7e-82 | 40.08% (474) | succinic semialdehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0132 | - | 0.0 | 80.94% (509) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv1731 | gabD2 | 7e-82 | 40.08% (474) | succinic semialdehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 2e-50 | 31.90% (464) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4136c | - | 1e-170 | 61.63% (490) | putative aldehyde dehydrogenase |
| M. marinum M | MMAR_3111 | gabD1_1 | 1e-115 | 45.26% (506) | succinate-semialdehyde dehydrogenase |
| M. avium 104 | MAV_4946 | - | 2e-67 | 35.39% (469) | aldehyde dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0889 | - | 0.0 | 81.34% (509) | succinic semialdehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_3430 | putA_2 | 1e-115 | 48.28% (495) | succinate-semialdehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0771 | - | 0.0 | 82.51% (509) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1760|M.bovis_AF2122/97 -------------MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKP
Rv1731|M.tuberculosis_H37Rv -------------MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKP
Mflv_0132|M.gilvum_PYR-GCK -----------------------MTATSDAHTANPFTGTGTITNPATGAV
Mvan_0771|M.vanbaalenii_PYR-1 --------------------MGFMTATSDVQPPHTFTGTGTIRNPATGAV
MSMEG_0889|M.smegmatis_MC2_155 -----------------------MTATPEVDLPNPYTGTGTIHNPATGAV
TH_3138|M.thermoresistible__bu -----------------------MTATSGVDA----TETATIRNPATGGV
MAB_4136c|M.abscessus_ATCC_199 -----------------------MTTTSENLVSTPSDTSHDVRNPANGQV
MUL_3430|M.ulcerans_Agy99 ---------------------MSSIATEPTMQKDDGQPQIPVENPATGEV
MMAR_3111|M.marinum_M MVCWVPYEQLRLAPAAKAVAVMMDTTNQANPAEADTRDEVVVKCPATGEI
MAV_4946|M.avium_104 ----------MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEY
MLBr_02573|M.leprae_Br4923 -------------------------------------MSIATINPATGET
.*
Mb1760|M.bovis_AF2122/97 LTTIPVGTAADVEAAFAEARAAQT--DWAKRPVIERAAVIRRYRDLVIEN
Rv1731|M.tuberculosis_H37Rv LTTIPVGTAADVEAAFAEARAAQT--DWAKRPVIERAAVIRRYRDLVIEN
Mflv_0132|M.gilvum_PYR-GCK AGTVHWTDPADVAQVAAGLRTAQR--EWEARGPKGRAKVLARYALWLGEH
Mvan_0771|M.vanbaalenii_PYR-1 AGEVRWTDPADVARLAAGLRTAQR--EWETRGPKGRAKVLARYAVWLGEH
MSMEG_0889|M.smegmatis_MC2_155 AGEVRWTDPADVPRIAAGLREAQK--EWEARGPKGRAKVLARYAVWLGDH
TH_3138|M.thermoresistible__bu AGEVRWTDPADVPRITAGLREAQR--HWEARGPKGRAKVLARYAVWLGEH
MAB_4136c|M.abscessus_ATCC_199 VGRVNWTDPSDIPGIVAQLAKAQP--SWERLGPEGRGQVLARFAQWLIDN
MUL_3430|M.ulcerans_Agy99 IGHVPDMSAAQIAELARRGRAAQP--GWEALGYEGRAVVLKRMQRWLVDN
MMAR_3111|M.marinum_M VGTVAVTTVDGVAAAAARLRAAQP--EWQRLGVSGRAYWLGRWRDWMLDH
MAV_4946|M.avium_104 VGKVPLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEER
MLBr_02573|M.leprae_Br4923 VKTFTPTTQDEVEDAIARAYARFD--NYRHTTFTQRAKWANATADLLEAE
. : : *. : .
Mb1760|M.bovis_AF2122/97 REFLMDLLQAEAGKARWAAQEEIVDL-IANANYYARVCVDLLKPRKAQPL
Rv1731|M.tuberculosis_H37Rv REFLMDLLQAEAGKARWAAQEEIVDL-IANANYYARVCVDLLKPRKAQPL
Mflv_0132|M.gilvum_PYR-GCK RAEIERLLIAETGKSAVDAAQEVPLI-LMITSYYVRTMEKALAPESRPAA
Mvan_0771|M.vanbaalenii_PYR-1 RDEIERLLIAETGKSAADAAQEVPLI-IMITSYYVRTMAKALAPETRPAS
MSMEG_0889|M.smegmatis_MC2_155 RDEIEKLLIAETGKSAVDAAQEVPLI-LMILSYYIKTVEKAMAPEKRPAP
TH_3138|M.thermoresistible__bu RDEIERLLIAETGKSAVDAAQEVPLI-LMITSYYIKTMEKALAPETRPAS
MAB_4136c|M.abscessus_ATCC_199 TGRIEAQLIAETGKSKIDGGIEIPSI-LAIIAYYAPKAAEFLAPESRPAS
MUL_3430|M.ulcerans_Agy99 ADQVIATICSETGKTYEDAQIAELIYGAAAFGFWADKAPRYLADERIHSS
MMAR_3111|M.marinum_M RDDLLTPLQLETGKSWGDAGIEIATV--QVINYWIDNAAEFLADQPVRPY
MAV_4946|M.avium_104 KDLFTGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVRTG
MLBr_02573|M.leprae_Br4923 ANQSAALMTLEMGKTLQSAKDEAMKC-AKGFRYYAEKAETLLADEP--AE
: * *:. :: : . .
Mb1760|M.bovis_AF2122/97 LPGIG--KTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVLKP
Rv1731|M.tuberculosis_H37Rv LPGIG--KTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVLKP
Mflv_0132|M.gilvum_PYR-GCK LPFLSIKKITVHYRPRPVVGIIAPWNYPVANALMDAIGALAAGCAVLLKP
Mvan_0771|M.vanbaalenii_PYR-1 LPFLSIKKITVHYRPRPVVGIIAPWNYPVANALMDAVGALAAGCAVLLKP
MSMEG_0889|M.smegmatis_MC2_155 LPFLSIKKIEVHYRPRAVVGIIAPWNYPVANAMMDAIGALAAGCSVLLKP
TH_3138|M.thermoresistible__bu MPLLKIKKITVHHRPRPVVGVIAPWNYPVANALMDAIGALAAGCAVLLKP
MAB_4136c|M.abscessus_ATCC_199 SIAMNTKKITVHQRPRKVVGVISPWNYPVALGYWDVIPALLAGCSVLLKP
MUL_3430|M.ulcerans_Agy99 SVFVKGKRLVLRYRPMGLIGVIGPWNYPLTNSFGDCIPALAAGNSVILKP
MMAR_3111|M.marinum_M GAANAAKKLTIVYEPYPLVGVITPWNGPLSVPLLDVPAALLAGCAVLSKP
MAV_4946|M.avium_104 G----YGQSIVHREPIGVVGAIVAWNVPLFLAVNKLGPALLAGCTVVLKP
MLBr_02573|M.leprae_Br4923 AAAVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKH
: .* :: : .** *: ** ** : *
Mb1760|M.bovis_AF2122/97 DSQTPYCALACAELLYRAGLPRALYAIVP-GPGSVVGTAITDNCDYLMFT
Rv1731|M.tuberculosis_H37Rv DSQTPYCALACAELLYRAGLPRALYAIVP-GPGSVVGTAITDNCDYLMFT
Mflv_0132|M.gilvum_PYR-GCK SERTPLTAELLLRGWLEAGGPD-VLALAQ-GAR-AVSEAVIDNSDFIQFT
Mvan_0771|M.vanbaalenii_PYR-1 SERTPLTAELLLRGWLDSGGPD-VLALAQ-GAR-EVSEAVIDNSDYIQFT
MSMEG_0889|M.smegmatis_MC2_155 SERTPLTAEVLLRGWLDSGAPE-VFALAQ-GAR-AVSEAVIDNSDYIQFT
TH_3138|M.thermoresistible__bu SERTPLTAELLLRGWLESGAPE-VFALAQ-GAR-EVSEAVVDNADFIQFT
MAB_4136c|M.abscessus_ATCC_199 SERTPLSDELIANGWAEIGGPP-VFEVVH-GAR-EVGEALVDNVDFVQFT
MUL_3430|M.ulcerans_Agy99 SEVTPLTSLLLAQGLAESGLPDGVFAVAT-GRG-GTGAAVIDEVDMIMFT
MMAR_3111|M.marinum_M SEFTPLAWQHAVEGWKQIGAPD-VLDVVF-GFG-ETGAALVDVVDYVMFT
MAV_4946|M.avium_104 AAETPLSANALAEAFAEAGLPEGVLSVVPGGIETGQALTSNTDVDIFSFT
MLBr_02573|M.leprae_Br4923 ASNVPQCALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLT
.* * * . . :*
Mb1760|M.bovis_AF2122/97 GSSATGSRLAEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACF
Rv1731|M.tuberculosis_H37Rv GSSATGSRLAEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACF
Mflv_0132|M.gilvum_PYR-GCK GSSATGAKVMERAARRLTPVSLELGGKDPMIVLEDADVDLAAHAAVWGAM
Mvan_0771|M.vanbaalenii_PYR-1 GSTATGVKVMERAARRLTPVSLELGGKDPMIVLEDADIDLAAHAAVWGAM
MSMEG_0889|M.smegmatis_MC2_155 GSSATGAKVMERAARRLTPVSLELGGKDPMIVLEDADIELAANAAVWGAM
TH_3138|M.thermoresistible__bu GSTATGIKVMERAARRLTPVSLELGGKDPMIVLEDADIELAANAAVWGAM
MAB_4136c|M.abscessus_ATCC_199 GSTATGKKIMERAARRLTPVSLELGGKDPMLVLPDADVKRAAHAAVWGSM
MUL_3430|M.ulcerans_Agy99 GSTATGRKVAVRAAERLIPASLELGGKDPMIVLADADIERAANHAAYYSM
MMAR_3111|M.marinum_M GSVGTGRRIAVAAAERLIPCGLELGGKDAMIVCADADIDRAVDGAVWGGF
MAV_4946|M.avium_104 GSSAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDLPSALPMLVFSGI
MLBr_02573|M.leprae_Br4923 GSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRV
** .* : *. : ****... :* ..:: . . .
Mb1760|M.bovis_AF2122/97 SNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTAYDFS--VDMGS
Rv1731|M.tuberculosis_H37Rv SNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTAYDFS--VDMGS
Mflv_0132|M.gilvum_PYR-GCK FNAGQTCVSVERVYVLDQVYDQFVDAVVRDVAKLQVGAGEGN----AFGA
Mvan_0771|M.vanbaalenii_PYR-1 FNAGQTCVSVERVYVLEQVYDQFVAAVVRDVESLKMGAGEGN----AFGA
MSMEG_0889|M.smegmatis_MC2_155 FNAGQTCVSVERVYVLESVYDQFVAATVRAVENLKMGAGEGY----DFGS
TH_3138|M.thermoresistible__bu FNAGQTCVSVERVYVLAPVYEQFVAAVVRAVEKLEVGAGEGR----HFGA
MAB_4136c|M.abscessus_ATCC_199 FNAGQTCVSVERVYVHDSIYEQFVDLVVEEVRGLEIGAGLDH----SVGA
MUL_3430|M.ulcerans_Agy99 FNCGQTCISIERCYVEAPVYDEFVAKVTEKVRAIRQGVPAGPGS-VDVGS
MMAR_3111|M.marinum_M AYTGQVCISVERIYVEAPVFDTFVSKLVARTSQLRQGMDAGHDYSCEIGS
MAV_4946|M.avium_104 MNSGQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVGLPSDP--AAQIGS
MLBr_02573|M.leprae_Br4923 QNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPD--TDVGP
** *:: * . : :. : * . .*.
Mb1760|M.bovis_AF2122/97 LISEAQLKTVSGHVDDATAKGAKVIAGGKARP-DIGPLFYEPTVLTNVAP
Rv1731|M.tuberculosis_H37Rv LISEAQLKTVSGHVDDATAKGAKVIAGGKARP-DIGPLFYEPTVLTNVAP
Mflv_0132|M.gilvum_PYR-GCK LIDDDQVAVTERHVADALAKGARALTGGTRGA--GSGSFYEPTVLVDVDH
Mvan_0771|M.vanbaalenii_PYR-1 LIDDSQVEITARHVEDALAKGARALTGGKRGS--GPGSFYEPTVLVDVDH
MSMEG_0889|M.smegmatis_MC2_155 LIDAGQVDITERHVNEALEKGAKALTGGKRPE--DGGSFYPPTVLVDVDH
TH_3138|M.thermoresistible__bu LIDESQLAVTERHVADAVARGAKVLTGGRRKD--GPGCFYEPTVLVDVDH
MAB_4136c|M.abscessus_ATCC_199 MIDENQLEVVDRHVRQAVSSGARALTGGARIP--GHGSFYAPTVLVDVDH
MUL_3430|M.ulcerans_Agy99 LTFPPQVETVQRHVEEAVERGAKVLTGGHRGR--TKGYWYEPTVLVDVNH
MMAR_3111|M.marinum_M MTTAQQLEIVSRHVDDAVRKGAKVLIGGKTRDPGGDGLFYEPTVLVDVDH
MAV_4946|M.avium_104 LISEKQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFFVQPTVFADVDN
MLBr_02573|M.leprae_Br4923 LATESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITK
: . : . ** ** : ***:.::
Mb1760|M.bovis_AF2122/97 EMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWAGSTAEGQR
Rv1731|M.tuberculosis_H37Rv EMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWAGSTAEGQR
Mflv_0132|M.gilvum_PYR-GCK AMLCMTEETFGPTLPIMRVSTVDEAVRLANDSPYGLSAAVFSKDLERAEA
Mvan_0771|M.vanbaalenii_PYR-1 SMACMTEETFGPTLPIMKVSSVEEAVRLANDSPYGLSAAVFSRDVDRAKA
MSMEG_0889|M.smegmatis_MC2_155 SMSCMNEETFGPTLPIMKVSSVEEAVRLANDSPYGLSASVFSKDTERAKK
TH_3138|M.thermoresistible__bu SMMCMTEETFGPTLPIMKVSSVAEAVRLANDTPYGLSGSVFSQDVERARE
MAB_4136c|M.abscessus_ATCC_199 SMDCMREETFGPTLPIMRYSEESEAIALANDSEYGLSASVWSKDRRRAER
MUL_3430|M.ulcerans_Agy99 DMACMREETFGPTLPIMKVADAEEAIRLANDSEYGLCAAVFSRDLAHAEA
MMAR_3111|M.marinum_M DMDCMREETFGPTLPVMKVRDVAEAIEKANDCRFGLSGSVWTRDKAKAID
MAV_4946|M.avium_104 KMTIAQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGSVWTADVQRGIA
MLBr_02573|M.leprae_Br4923 DMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRH
* :* ***. .: :*: ** :** . .:: . .
Mb1760|M.bovis_AF2122/97 IAARLRSGTVNVDEGYAFAWGSLSAPMGGMG-LSGVGRRHG-PEGLLKYT
Rv1731|M.tuberculosis_H37Rv IAARLRSGTVNVDEGYAFAWGSLSAPMGGMG-LSGVGRRHG-PEGLLKYT
Mflv_0132|M.gilvum_PYR-GCK VAVQLDCGGVNIND-VISNLMCTTAPMGGWK-TSGIGARFGGPEGLRKYC
Mvan_0771|M.vanbaalenii_PYR-1 VALQLDCGGVNVND-VISNLMCTTAPMGGWK-SSGIGARFGGPEGLRKYC
MSMEG_0889|M.smegmatis_MC2_155 IALQLDCGAVNIND-VISNLMCTTAPMGGWK-TSGIGARFGGVDGVRKFC
TH_3138|M.thermoresistible__bu IALQLDCGAVNIND-VISNLMATTAPMGGWK-TSGIGARFGGPEGLRKYC
MAB_4136c|M.abscessus_ATCC_199 VALQLDCGTVNIND-VIMNLSCLTAPHGGWK-GSGLGSRFGGVDGLRKYC
MUL_3430|M.ulcerans_Agy99 VARRVNSGAVTVND-ALLNYTALELPMGGAKPGSGVGYRHG-PGGIRKYC
MMAR_3111|M.marinum_M IARRLNTGTVNINN-VITGIFQIGVPMAGWK-ESGLGTRSGGAEGIRKYC
MAV_4946|M.avium_104 VSEKIRTGTYAINW----YAFDPCCPFGGYK-NSGIGRENG-PEGVEHFT
MLBr_02573|M.leprae_Br4923 FIDNIVAGQVFING---MTVSYPELPFGGIK-RSGYGRELS-THGIREFC
. .: * :: * .* ** * . . *: .:
Mb1760|M.bovis_AF2122/97 ESQTIATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR-----
Rv1731|M.tuberculosis_H37Rv ESQTIATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR-----
Mflv_0132|M.gilvum_PYR-GCK RIETVVAPRTNVGAGGNYYNNSPRALKRMNTMMTKLALIRPRRVAK-
Mvan_0771|M.vanbaalenii_PYR-1 RIETVVSPRTNVGAGGNYYNNSLRALKRMNKLMTKLALIRPRRVAK-
MSMEG_0889|M.smegmatis_MC2_155 KQETVVAPRTSVGAGGTYYNNSHKALARMNRLMTKLALARPRRTAK-
TH_3138|M.thermoresistible__bu RVETVVEPRTGIGAGGTYYNNSFKSLGMMNKLLTRMALVRPRRLAK-
MAB_4136c|M.abscessus_ATCC_199 RTEAIVDTRVTLPSEPLWYSGPSWLAPVALKSLTKLSNKALRPFRR-
MUL_3430|M.ulcerans_Agy99 RQQALLISRFHARRDVHMYPYSARRTRILGRLVGRLYRG-VRGTDS-
MMAR_3111|M.marinum_M HPKSIVAERVAMKKELLWYPYSRKKGSFAEKVVRMLSARDWRRRLGR
MAV_4946|M.avium_104 QQKSVLMPMGYTLEG--------------------------------
MLBr_02573|M.leprae_Br4923 NIKTVWIA---------------------------------------
. :::