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M. thermoresistible (build 8) TH_3898 (-)

annotation: short chain dehydrogenase
coordinates: 1272089 - 1272880
length: 264

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3898--100% (264)short chain dehydrogenase
M. thermoresistible (build 8)TH_2623-9e-4340.94% (254) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3505-3e-3841.80% (244) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0950c-1e-12182.13% (263) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1825-1e-12585.93% (263) short chain dehydrogenase
M. tuberculosis H37RvRv0927c-1e-12182.13% (263) short chain dehydrogenase
M. leprae Br4923MLBr_02565fabG6e-2033.87% (248) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4632-1e-10070.72% (263) short chain dehydrogenase
M. marinum MMMAR_4581-1e-12584.79% (263) short-chain type dehydrogenase/reductase
M. avium 104MAV_1046-1e-12584.79% (263) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_5584-1e-12785.93% (263) short chain dehydrogenase
M. ulcerans Agy99MUL_4442-1e-12483.65% (263) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_4921-1e-12586.31% (263) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
MAV_1046|M.avium_104                --------------------------------------------------
Mflv_1825|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4921|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3898|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5584|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
                                                                                      

Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
MAV_1046|M.avium_104                --------------------------------------------------
Mflv_1825|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4921|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3898|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5584|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
                                                                                      

Mb0950c|M.bovis_AF2122/97           --------------------------------------MILDMFR-----
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------MILDMFR-----
MMAR_4581|M.marinum_M               --------------------------------------MILDRFR-----
MUL_4442|M.ulcerans_Agy99           --------------------------------------MILDRFR-----
MAV_1046|M.avium_104                --------------------------------------MILDRFR-----
Mflv_1825|M.gilvum_PYR-GCK          --------------------------------------MILDRFR-----
Mvan_4921|M.vanbaalenii_PYR-1       ----------------------------MTRGRQREANVILDRFR-----
TH_3898|M.thermoresistible__bu      --------------------------------------VILDRFR-----
MSMEG_5584|M.smegmatis_MC2_155      -------------------------------------MLILDRFR-----
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------MILDRFK-----
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
                                                                            *: *      

Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
MAV_1046|M.avium_104                --------------------------------------------------
Mflv_1825|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4921|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3898|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5584|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
                                                                                      

Mb0950c|M.bovis_AF2122/97           ----------LDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
Rv0927c|M.tuberculosis_H37Rv        ----------LDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
MMAR_4581|M.marinum_M               ----------LDDQVAVITGGGRGLGAAIALAFAEAGADVVIASRTQSQL
MUL_4442|M.ulcerans_Agy99           ----------LDDQVAVITGGGRGFGAAIALAFAEAGADVVIASRTQSQL
MAV_1046|M.avium_104                ----------LDDKVAVITGAGRGLGAAIAVAFAEAGADVLIASRTESQL
Mflv_1825|M.gilvum_PYR-GCK          ----------LDDQVAVVTGAGRGLGAAMALAFAEAGADVLIAARTQSQL
Mvan_4921|M.vanbaalenii_PYR-1       ----------LDDQVAVVTGAGRGLGAAMALAFAEAGADVLIAARTRSQL
TH_3898|M.thermoresistible__bu      ----------LDDRVAVVTGAGRGLGAAMAVAFAEAGADVLISARTQAQL
MSMEG_5584|M.smegmatis_MC2_155      ----------LDDKVAVVTGAGRGLGAAIALAFAEAGADVVIAARTQSQL
MAB_4632|M.abscessus_ATCC_1997      ----------LDGNVAVVTGAGRGLGAAIAEAFAQAGADVLIASRTESQL
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAID-VESAA
                                              *:..**::**..**:***:* ..*. ** *:    . :  

Mb0950c|M.bovis_AF2122/97           DAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFG-KLDIVVNNVG
Rv0927c|M.tuberculosis_H37Rv        DAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFG-KLDIVVNNVG
MMAR_4581|M.marinum_M               DEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFG-RLDIVVNNVG
MUL_4442|M.ulcerans_Agy99           DEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFG-RLDIVVNNVG
MAV_1046|M.avium_104                EAVAEQVRAAGRRAHVVAADLAHPESTAELAGRAVEAFG-KLDIVVNNVG
Mflv_1825|M.gilvum_PYR-GCK          EAVAEQIAGTGRRAHIVVADLARPEDTAGLAAQAVEAFG-RLDIVVNNVG
Mvan_4921|M.vanbaalenii_PYR-1       EEVAEQIEGTGRRAHIVVADLAHAEDTAALAAGAVEAFG-RLDIVVNNVG
TH_3898|M.thermoresistible__bu      EEVAAQIAATGRRAHVVAADLAHPEATAELAGAAVEAFG-KLDIVVNNVG
MSMEG_5584|M.smegmatis_MC2_155      DEVAGQVAGAGRKAHVVVADLAHPDATAELVQAAIEAFG-KLDVVVNNVG
MAB_4632|M.abscessus_ATCC_1997      REVAAKVQAAGRQAEVVVADLSDTEASAALAQKAVDRFG-RLDVVVNNVG
MLBr_02565|M.leprae_Br4923          EALDETANRVG--GTTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAG
                                      :       *  .  :  *::  :    :.       * : *::***.*

Mb0950c|M.bovis_AF2122/97           GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVINIS
Rv0927c|M.tuberculosis_H37Rv        GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVINIS
MMAR_4581|M.marinum_M               GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGSIINIT
MUL_4442|M.ulcerans_Agy99           GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGGIINIT
MAV_1046|M.avium_104                GTMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGNIINIT
Mflv_1825|M.gilvum_PYR-GCK          GTMPNALLNTSTKDMRDAFTFNVATAHALTTAAVPLMLEHSGGGSIINIT
Mvan_4921|M.vanbaalenii_PYR-1       GTMPNALLTTSTKDMRDAFAFNVATAHALTTAAVPLMLEHSGGGSIINIT
TH_3898|M.thermoresistible__bu      GTMPGPLLNTSAKEMRDAFTFNVGTAHALTTAAVPLMLKHSGGGSIINIT
MSMEG_5584|M.smegmatis_MC2_155      GTMPAPLLNTSTKDLRDAFTFNVSTAHALTSAAVPLMLEHSGGGSIINIT
MAB_4632|M.abscessus_ATCC_1997      GTMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLK-SDNASVINIT
MLBr_02565|M.leprae_Br4923          ITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGR-VIVLS
                                     *    :          .: .*: : : *  . *      ...  :* ::

Mb0950c|M.bovis_AF2122/97           STMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSILTS
Rv0927c|M.tuberculosis_H37Rv        STMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSILTS
MMAR_4581|M.marinum_M               STMGRVAGRGFAAYGTAKAALAHYTRLAALDLCPR-IRVNAIAPGSILTS
MUL_4442|M.ulcerans_Agy99           STMGRVAGRGFAAYGTAKVALAHYTRLAALDLCPR-IRVNAIAPGSILTS
MAV_1046|M.avium_104                STMGRLAGRGFAAYGTAKAALSHYTRLTALDLCPR-IRVNAIAPGSILTS
Mflv_1825|M.gilvum_PYR-GCK          STMGRVAGRGFAAYGTAKAALAHYTRLSALDLAPR-IRVNAIAPGSILTS
Mvan_4921|M.vanbaalenii_PYR-1       STMGRLAGRGFAAYGTAKAALAHYTRLSALDLAPR-IRVNAIAPGSILTS
TH_3898|M.thermoresistible__bu      STMGRLAGRGFAAYGTAKAALAHYTRLAALDLAPR-IRVNAIAPGSILTS
MSMEG_5584|M.smegmatis_MC2_155      STMGRLAGRGFVAYGTAKAALAHYTRLAALDLCPR-IRVNAIAPGSILTS
MAB_4632|M.abscessus_ATCC_1997      STMGRLPGRAFLGYCTAKGALAHYTRTAAMDLSPR-IRVNGIAPGSILTS
MLBr_02565|M.leprae_Br4923          SMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIETQ
                                    *  *    *.   * *** .:   *:  * .*. : : :*.:*** * *.

Mb0950c|M.bovis_AF2122/97           ALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTL
Rv0927c|M.tuberculosis_H37Rv        ALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTL
MMAR_4581|M.marinum_M               ALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTL
MUL_4442|M.ulcerans_Agy99           ALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTL
MAV_1046|M.avium_104                ALDVVASNDELRAPMEKATPLRRLGDPVDIASAAVYLASPAGEFLTGKTL
Mflv_1825|M.gilvum_PYR-GCK          ALEIVASNDDLRDPMEKATPMKRLGDPLDIAAAAVYLASPAGSYLTGKTL
Mvan_4921|M.vanbaalenii_PYR-1       ALEIVADNDELRGPMEKATPLRRLGDPLDIAAAAVYLASPAGSYLTGKTL
TH_3898|M.thermoresistible__bu      ALDVVASNDELRTPMEQATPLRRLGEPADIAAAAVYLASPAGSYLTGKVL
MSMEG_5584|M.smegmatis_MC2_155      ALDVVASNDALREPMEKVTPLRRLGDPADIAAAAVYLASPAGAYLTGKTL
MAB_4632|M.abscessus_ATCC_1997      ALEVVAGNDEMRNTLEQNTPLHRLGDPADIAAAAVYLASPAGSFLTGKVL
MLBr_02565|M.leprae_Br4923          MTAAIP--LATREVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTGNVI
                                        :.     *   .: ..: : * * *:* : .*:* **.  :**:.:

Mb0950c|M.bovis_AF2122/97           EVDGGLTFPNLDLPIPDL-
Rv0927c|M.tuberculosis_H37Rv        EVDGGLTFPNLDLPIPDL-
MMAR_4581|M.marinum_M               EVDGGLTHPNLDIPVPDL-
MUL_4442|M.ulcerans_Agy99           EVDGGLTHPNLDIPVPDL-
MAV_1046|M.avium_104                EVDGGLTYPNLDIPVPDL-
Mflv_1825|M.gilvum_PYR-GCK          EVDGGITFPNLELPIPDL-
Mvan_4921|M.vanbaalenii_PYR-1       EVDGGITFPNLDLPIPDL-
TH_3898|M.thermoresistible__bu      EVDGGLTRPNLDMPIPDL-
MSMEG_5584|M.smegmatis_MC2_155      EVDGGLTMPNLDLPIPDL-
MAB_4632|M.abscessus_ATCC_1997      EVDGGLIAPNLDIPLPDLA
MLBr_02565|M.leprae_Br4923          RVCGQAMLGA---------
                                    .* *