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M. avium 104 MAV_3248 (-)

annotation: Mmp14A protein
coordinates: 3385926 - 3388817
length: 963

MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGVPSLEQVEAEHAVSLSPIGAPSFKAMERL
GEDFKETNTGALAMILLEGQQQLGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAY
VQVNLNGNAGAAAGDESVAAIRKLVQEASPPPGLKVYVTGPAPIVADMNIAGQKTVMLVTLASLIVIFVT
LLLVYRSVITVILLLLIVGLELQIARGMVALLGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEA
RQAGESREEAFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAVLVALTLGPALL
AAGARFGLFEPRRAVSARRWRRIGTAIVRWPAPILIATLAVSLVGLLALPNYRPSYDDQKFIPDSIPANV
GYAAAARHFPGQRMQMPEILLVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTTIP
WIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMRELVATTHHMVQTTHEMQEITGELR
DHISDFEDFWRPLRSYFYWEKHCYDIPICFSLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQI
PPMIETMSGMRTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGIINGSDSFKRVEKV
FMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEESLKGTPLENSKIYLTGTAAITKDLVDGSKFDLL
IAGVSALCLIFIIMLIMTRSFIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLAVG
SDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAMVVSDLRSIGQVGTTIGLGLLFD
TLIVRAFMTPSVAALLGRWFWWPQLVRPRPASTMLRPTGPRPLVRSLLLKQPQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3248--100% (963)Mmp14A protein
M. avium 104MAV_3249-0.064.27% (932) Mmp14A protein
M. avium 104MAV_3863-0.056.60% (954) MmpL4 protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.062.20% (947) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.057.64% (942) transport protein
M. tuberculosis H37RvRv0450cmmpL40.062.30% (947) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.061.77% (939) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_4116c-0.067.37% (947) putative membrane protein, MmpL
M. marinum MMMAR_0771mmpL5_20.063.12% (941) transmembrane transport protein MmpL5_2
M. smegmatis MC2 155MSMEG_0381-0.067.47% (959) Mmp14a protein
M. thermoresistible (build 8)TH_3056-0.064.56% (948) PUTATIVE Mmp14a protein
M. ulcerans Agy99MUL_0757mmpL50.056.75% (941) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.058.93% (935) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02378|M.leprae_Br4923          ----MTVKCANDLDT--HTKPPFVARMIHRFAVPIILVWLAIAVTVSVFI
MMAR_0771|M.marinum_M               ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFI
Mb0458c|M.bovis_AF2122/97           ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
Rv0450c|M.tuberculosis_H37Rv        ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
Mflv_4418|M.gilvum_PYR-GCK          ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAV
Mvan_1936|M.vanbaalenii_PYR-1       ---------------MADAGRSGIGRIIHLLAVPIVLGWIALTVLTNVAV
MUL_0757|M.ulcerans_Agy99           MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV
MAB_4116c|M.abscessus_ATCC_199      ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV
MSMEG_0381|M.smegmatis_MC2_155      --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI
TH_3056|M.thermoresistible__bu      --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV
MAV_3248|M.avium_104                --------MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGV
                                                         . :  :*:  :* ::* *: : .  .  :

MLBr_02378|M.leprae_Br4923          PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGDKP
MMAR_0771|M.marinum_M               PSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGKDA
Mb0458c|M.bovis_AF2122/97           PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP
Rv0450c|M.tuberculosis_H37Rv        PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP
Mflv_4418|M.gilvum_PYR-GCK          PSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSAMVVLEGEQP
Mvan_1936|M.vanbaalenii_PYR-1       PSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFDSDSSAMVVLEGEQP
MUL_0757|M.ulcerans_Agy99           PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQEP
MAB_4116c|M.abscessus_ATCC_199      PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGEGT
MSMEG_0381|M.smegmatis_MC2_155      PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQEP
TH_3056|M.thermoresistible__bu      PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQEP
MAV_3248|M.avium_104                PSLEQVEAEHAVSLSPIGAPSFKAMERLGEDFKETNTGALAMILLEGQQQ
                                    * ** *   :::.: .  **:  :* ::*  * * :: :  ::::**.  

MLBr_02378|M.leprae_Br4923          LGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAYVQ
MMAR_0771|M.marinum_M               LGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAYVQ
Mb0458c|M.bovis_AF2122/97           LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ
Rv0450c|M.tuberculosis_H37Rv        LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ
Mflv_4418|M.gilvum_PYR-GCK          LGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQ
Mvan_1936|M.vanbaalenii_PYR-1       LGDAAHRYYDELIGKLEADTANVQHVADFWGDPLTASGAQSTDGKAAYVQ
MUL_0757|M.ulcerans_Agy99           LGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAYVQ
MAB_4116c|M.abscessus_ATCC_199      LGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAYVQ
MSMEG_0381|M.smegmatis_MC2_155      LGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAYVQ
TH_3056|M.thermoresistible__bu      LGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAFVQ
MAV_3248|M.avium_104                LGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAYVQ
                                    **  ** :** ::  *. .   ** : ::******  ..:* * ***:**

MLBr_02378|M.leprae_Br4923          LSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMHHS
MMAR_0771|M.marinum_M               LNLAGNQGEPLANESVEAVRKIVKETP-APPGVTTYVTGAAALVSDMHSS
Mb0458c|M.bovis_AF2122/97           LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS
Rv0450c|M.tuberculosis_H37Rv        LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS
Mflv_4418|M.gilvum_PYR-GCK          VYLQGNQGEPRANEAVAAVREIVDRTP-APPGIKAYVTGGAPLVADQHSA
Mvan_1936|M.vanbaalenii_PYR-1       VYLQGNQGEPRANEAVAAVREIVDQTP-APPGLKAYVTGGAPLVADQHNA
MUL_0757|M.ulcerans_Agy99           VKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQLA
MAB_4116c|M.abscessus_ATCC_199      LNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMAES
MSMEG_0381|M.smegmatis_MC2_155      INLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMGES
TH_3056|M.thermoresistible__bu      VNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAGDS
MAV_3248|M.avium_104                VNLNGNAGAAAGDESVAAIRKLVQEAS-PPPGLKVYVTGPAPIVADMNIA
                                    : * *  *    :*:: *::  *      * *: .:*** :.: :*   :

MLBr_02378|M.leprae_Br4923          GDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVAL
MMAR_0771|M.marinum_M               GDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVELTAARGVVAL
Mb0458c|M.bovis_AF2122/97           GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV
Rv0450c|M.tuberculosis_H37Rv        GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV
Mflv_4418|M.gilvum_PYR-GCK          GDTSVLRVTLITIGVIAVMLLIVFRSVATMVLILFMVFAELGAARGIVAF
Mvan_1936|M.vanbaalenii_PYR-1       GDKSVFRVTLITIGVIAVMLLLVFRSVATMVLILFMVFAELGAARGIVAF
MUL_0757|M.ulcerans_Agy99           GDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAF
MAB_4116c|M.abscessus_ATCC_199      GNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLVAF
MSMEG_0381|M.smegmatis_MC2_155      GNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVSF
TH_3056|M.thermoresistible__bu      GTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAY
MAV_3248|M.avium_104                GQKTVMLVTLASLIVIFVTLLLVYRSVITVILLLLIVGLELQIARGMVAL
                                    *  ::  :   :. ** : **:.:* .    ::*  *      :** *: 

MLBr_02378|M.leprae_Br4923          LGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAF
MMAR_0771|M.marinum_M               LGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEARQAGEDKETAF
Mb0458c|M.bovis_AF2122/97           LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY
Rv0450c|M.tuberculosis_H37Rv        LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY
Mflv_4418|M.gilvum_PYR-GCK          LADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY
Mvan_1936|M.vanbaalenii_PYR-1       LANAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY
MUL_0757|M.ulcerans_Agy99           LGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAY
MAB_4116c|M.abscessus_ATCC_199      LGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRESAY
MSMEG_0381|M.smegmatis_MC2_155      LALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQAY
TH_3056|M.thermoresistible__bu      LGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAY
MAV_3248|M.avium_104                LGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEARQAGESREEAF
                                    *.    :**:*:...**.   **:.***.**  *******  .:.:: *:

MLBr_02378|M.leprae_Br4923          YTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAV
MMAR_0771|M.marinum_M               YTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAVMV
Mb0458c|M.bovis_AF2122/97           YTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVAV
Rv0450c|M.tuberculosis_H37Rv        YTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAV
Mflv_4418|M.gilvum_PYR-GCK          YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIA
Mvan_1936|M.vanbaalenii_PYR-1       YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVMA
MUL_0757|M.ulcerans_Agy99           YTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAT
MAB_4116c|M.abscessus_ATCC_199      YTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAVAV
MSMEG_0381|M.smegmatis_MC2_155      YTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAV
TH_3056|M.thermoresistible__bu      FTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVAV
MAV_3248|M.avium_104                YTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAVLV
                                    :* : .. :*:*.** **:**  ** *:*:*:*:.:*:* *:*  :.* .

MLBr_02378|M.leprae_Br4923          ALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCA
MMAR_0771|M.marinum_M               ALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRWPLPVLAATLA
Mb0458c|M.bovis_AF2122/97           ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA
Rv0450c|M.tuberculosis_H37Rv        ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA
Mflv_4418|M.gilvum_PYR-GCK          ALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA
Mvan_1936|M.vanbaalenii_PYR-1       ALTLGPAVVAIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA
MUL_0757|M.ulcerans_Agy99           ALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAVA
MAB_4116c|M.abscessus_ATCC_199      ALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAATVA
MSMEG_0381|M.smegmatis_MC2_155      ALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATIA
TH_3056|M.thermoresistible__bu      ALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAVA
MAV_3248|M.avium_104                ALTLGPALLAAGARFG-LFEPRRAVSARRWRRIGTAIVRWPAPILIATLA
                                    **** ** :    ***  ::*:*    : **::*. :**** *:*  : *

MLBr_02378|M.leprae_Br4923          IAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PEIL
MMAR_0771|M.marinum_M               VALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFSQARMK-PDIL
Mb0458c|M.bovis_AF2122/97           IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL
Rv0450c|M.tuberculosis_H37Rv        IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL
Mflv_4418|M.gilvum_PYR-GCK          LALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQHFGSARMN-PELL
Mvan_1936|M.vanbaalenii_PYR-1       LALVGLVALPGYKTNYDSRDYLPEDVPANVGYAVADRHFGSARMN-PELL
MUL_0757|M.ulcerans_Agy99           LALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PEVL
MAB_4116c|M.abscessus_ATCC_199      VALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPDIL
MSMEG_0381|M.smegmatis_MC2_155      VAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDIL
TH_3056|M.thermoresistible__bu      LSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDVV
MAV_3248|M.avium_104                VSLVGLLALPNYRPSYDDQKFIPDSIPANVGYAAAARHFPGQRMQMPEIL
                                    ::::**::**.*...*    ::*  :**. *  .* :**    *  *:::

MLBr_02378|M.leprae_Br4923          MIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSIP
MMAR_0771|M.marinum_M               MIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTSIP
Mb0458c|M.bovis_AF2122/97           MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP
Rv0450c|M.tuberculosis_H37Rv        MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP
Mflv_4418|M.gilvum_PYR-GCK          MVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIP
Mvan_1936|M.vanbaalenii_PYR-1       MVESDHDLRNPADFLVIDKIAKAIFRVPGVARVQTITRPDGKPIKHTTIP
MUL_0757|M.ulcerans_Agy99           MVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSIP
MAB_4116c|M.abscessus_ATCC_199      LIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSSVP
MSMEG_0381|M.smegmatis_MC2_155      LVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP
TH_3056|M.thermoresistible__bu      LIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTIP
MAV_3248|M.avium_104                LVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTTIP
                                    ::::::*:**.:*:*:::::*: :: * *:: **::***:*  :.*:::*

MLBr_02378|M.leprae_Br4923          FQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLTE
MMAR_0771|M.marinum_M               FQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQLAN
Mb0458c|M.bovis_AF2122/97           FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS
Rv0450c|M.tuberculosis_H37Rv        FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS
Mflv_4418|M.gilvum_PYR-GCK          FQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSA
Mvan_1936|M.vanbaalenii_PYR-1       FQMSMRSTTSRLNEKYMQDRMADMLVQADAMQTNVDTMTKMQSLMTQMSA
MUL_0757|M.ulcerans_Agy99           FLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMAD
MAB_4116c|M.abscessus_ATCC_199      FMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQMVD
MSMEG_0381|M.smegmatis_MC2_155      FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVA
TH_3056|M.thermoresistible__bu      FMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMVA
MAV_3248|M.avium_104                WIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMRELVA
                                    : :**  : .     : :    .:* *.: :   :  : :*  *   :  

MLBr_02378|M.leprae_Br4923          NTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPICW
MMAR_0771|M.marinum_M               NTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWEKHCYDIPICS
Mb0458c|M.bovis_AF2122/97           TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW
Rv0450c|M.tuberculosis_H37Rv        TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW
Mflv_4418|M.gilvum_PYR-GCK          TTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVRNYFYWEPHCYDIPVCW
Mvan_1936|M.vanbaalenii_PYR-1       ATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPVRNYFYWEPHCYNIPVCA
MUL_0757|M.ulcerans_Agy99           VTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVCW
MAB_4116c|M.abscessus_ATCC_199      TTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPICW
MSMEG_0381|M.smegmatis_MC2_155      TTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLCW
TH_3056|M.thermoresistible__bu      TTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPICW
MAV_3248|M.avium_104                TTHHMVQTTHEMQEITGELRDHISDFEDFWRPLRSYFYWEKHCYDIPICF
                                     **  :            :*: : :::** **:*.*::*: **:.**:* 

MLBr_02378|M.leprae_Br4923          SFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMESM
MMAR_0771|M.marinum_M               SFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETFPPMIETMESM
Mb0458c|M.bovis_AF2122/97           SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM
Rv0450c|M.tuberculosis_H37Rv        SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM
Mflv_4418|M.gilvum_PYR-GCK          TMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRSM
Mvan_1936|M.vanbaalenii_PYR-1       TMRSVFDTLDGINPLTDDIQELIPDLERLDALMPQLIALLPSQIESMRNM
MUL_0757|M.ulcerans_Agy99           SLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKSM
MAB_4116c|M.abscessus_ATCC_199      SIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMKST
MSMEG_0381|M.smegmatis_MC2_155      SIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLENS
TH_3056|M.thermoresistible__bu      SIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMESS
MAV_3248|M.avium_104                SLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQIPPMIETMSGM
                                    ::**:** ***:: : : :  ::  : .:* ::**:   :*  *  : . 

MLBr_02378|M.leprae_Br4923          RTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKN
MMAR_0771|M.marinum_M               RLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVFKN
Mb0458c|M.bovis_AF2122/97           RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN
Rv0450c|M.tuberculosis_H37Rv        RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN
Mflv_4418|M.gilvum_PYR-GCK          QAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDN
Mvan_1936|M.vanbaalenii_PYR-1       QSMMLTMYQSQKGLQDQMASQSEDADAMGEAFDDSMNDDSFYLPPEAFDN
MUL_0757|M.ulcerans_Agy99           KAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNN
MAB_4116c|M.abscessus_ATCC_199      RESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVLKN
MSMEG_0381|M.smegmatis_MC2_155      RSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILEN
TH_3056|M.thermoresistible__bu      RTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALEN
MAV_3248|M.avium_104                RTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGIING
                                    :  :*  : :  *   *     .:. :**:*** : *********  :..

MLBr_02378|M.leprae_Br4923          TD-FKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALK
MMAR_0771|M.marinum_M               ED-FKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEESLK
Mb0458c|M.bovis_AF2122/97           KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK
Rv0450c|M.tuberculosis_H37Rv        KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK
Mflv_4418|M.gilvum_PYR-GCK          DD-FKRGMENFISPDGRSVRFIISHEGDPATVEGISEVVPIKTAAKEAIK
Mvan_1936|M.vanbaalenii_PYR-1       DD-FKRGIENFISPDGKSVRFIIAHEGDPATVEGISRVLPIKTAAKEAIK
MUL_0757|M.ulcerans_Agy99           PD-FKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIK
MAB_4116c|M.abscessus_ATCC_199      KD-FQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEALK
MSMEG_0381|M.smegmatis_MC2_155      ED-FKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALK
TH_3056|M.thermoresistible__bu      KD-FQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALK
MAV_3248|M.avium_104                SDSFKRVEKVFMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEESLK
                                     * *:*  : *:*.**:  *::: :.*** :  *:  :  *  **:*::*

MLBr_02378|M.leprae_Br4923          GTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRA
MMAR_0771|M.marinum_M               GTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIFIIMLILTRA
Mb0458c|M.bovis_AF2122/97           GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA
Rv0450c|M.tuberculosis_H37Rv        GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA
Mflv_4418|M.gilvum_PYR-GCK          GTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLIFVIMLVITRS
Mvan_1936|M.vanbaalenii_PYR-1       GTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGIAAVTLIFVIMLIITRS
MUL_0757|M.ulcerans_Agy99           GTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRS
MAB_4116c|M.abscessus_ATCC_199      GTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMTRS
MSMEG_0381|M.smegmatis_MC2_155      GTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRS
TH_3056|M.thermoresistible__bu      GTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRS
MAV_3248|M.avium_104                GTPLENSKIYLTGTAAITKDLVDGSKFDLLIAGVSALCLIFIIMLIMTRS
                                    ***** : : : *:.:   :: :*   **:**.:::: ***:**:.:**:

MLBr_02378|M.leprae_Br4923          FVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVG
MMAR_0771|M.marinum_M               FVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLAVG
Mb0458c|M.bovis_AF2122/97           FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG
Rv0450c|M.tuberculosis_H37Rv        FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG
Mflv_4418|M.gilvum_PYR-GCK          VVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVG
Mvan_1936|M.vanbaalenii_PYR-1       VVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVG
MUL_0757|M.ulcerans_Agy99           VVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVG
MAB_4116c|M.abscessus_ATCC_199      LVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLAVG
MSMEG_0381|M.smegmatis_MC2_155      FIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVG
TH_3056|M.thermoresistible__bu      VIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVG
MAV_3248|M.avium_104                FIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLAVG
                                    .:** ****** :*******:***:**::  : ::: **. :**:*****

MLBr_02378|M.leprae_Br4923          SDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVV
MMAR_0771|M.marinum_M               SDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASMAV
Mb0458c|M.bovis_AF2122/97           SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV
Rv0450c|M.tuberculosis_H37Rv        SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV
Mflv_4418|M.gilvum_PYR-GCK          SDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAF
Mvan_1936|M.vanbaalenii_PYR-1       SDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVVTSAGLVFAFTMASFAF
MUL_0757|M.ulcerans_Agy99           ADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAV
MAB_4116c|M.abscessus_ATCC_199      SDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSMIV
MSMEG_0381|M.smegmatis_MC2_155      SDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV
TH_3056|M.thermoresistible__bu      SDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIV
MAV_3248|M.avium_104                SDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAMVV
                                    :****:**:*:*:*: .*::*****:*.*:* *** ****** ** :: .

MLBr_02378|M.leprae_Br4923          SDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRP
MMAR_0771|M.marinum_M               SDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFWWPMRVRTRP
Mb0458c|M.bovis_AF2122/97           SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP
Rv0450c|M.tuberculosis_H37Rv        SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP
Mflv_4418|M.gilvum_PYR-GCK          SDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKFRSAA
Mvan_1936|M.vanbaalenii_PYR-1       SDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKVRSHA
MUL_0757|M.ulcerans_Agy99           SELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP
MAB_4116c|M.abscessus_ATCC_199      SDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSPRP
MSMEG_0381|M.smegmatis_MC2_155      SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRP
TH_3056|M.thermoresistible__bu      SDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRP
MAV_3248|M.avium_104                SDLRSIGQVGTTIGLGLLFDTLIVRAFMTPSVAALLGRWFWWPQLVRPRP
                                    *:*  :.******.:******::**:** *::**:**:*****      .

MLBr_02378|M.leprae_Br4923          LLTVAAPVGLP-PDRSLVYSD----
MMAR_0771|M.marinum_M               ARTPSSPTADPEPDRALAMSGER--
Mb0458c|M.bovis_AF2122/97           ARTPTVPSETQPAGRPLAMSSDRLG
Rv0450c|M.tuberculosis_H37Rv        ARTPTVPSETQPAGRPLAMSSDRLG
Mflv_4418|M.gilvum_PYR-GCK          SERRLARIGVQPATAGR--------
Mvan_1936|M.vanbaalenii_PYR-1       SQRRLAALNH---------------
MUL_0757|M.ulcerans_Agy99           APQPWPTPAPTPPPATTSV------
MAB_4116c|M.abscessus_ATCC_199      VGAVRGWRGPR-LVRSVLQRN----
MSMEG_0381|M.smegmatis_MC2_155      ASAMLRSVGPRPLVRSLLLRD----
TH_3056|M.thermoresistible__bu      ASAMLRPVGPRPLVRSLLLRD----
MAV_3248|M.avium_104                ASTMLRPTGPRPLVRSLLLKQPQ--