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MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGVPSLEQVEAEHAVSLSPIGAPSFKAMERL GEDFKETNTGALAMILLEGQQQLGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAY VQVNLNGNAGAAAGDESVAAIRKLVQEASPPPGLKVYVTGPAPIVADMNIAGQKTVMLVTLASLIVIFVT LLLVYRSVITVILLLLIVGLELQIARGMVALLGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEA RQAGESREEAFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAVLVALTLGPALL AAGARFGLFEPRRAVSARRWRRIGTAIVRWPAPILIATLAVSLVGLLALPNYRPSYDDQKFIPDSIPANV GYAAAARHFPGQRMQMPEILLVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTTIP WIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMRELVATTHHMVQTTHEMQEITGELR DHISDFEDFWRPLRSYFYWEKHCYDIPICFSLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQI PPMIETMSGMRTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGIINGSDSFKRVEKV FMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEESLKGTPLENSKIYLTGTAAITKDLVDGSKFDLL IAGVSALCLIFIIMLIMTRSFIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLAVG SDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAMVVSDLRSIGQVGTTIGLGLLFD TLIVRAFMTPSVAALLGRWFWWPQLVRPRPASTMLRPTGPRPLVRSLLLKQPQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3248 | - | - | 100% (963) | Mmp14A protein |
M. avium 104 | MAV_3249 | - | 0.0 | 64.27% (932) | Mmp14A protein |
M. avium 104 | MAV_3863 | - | 0.0 | 56.60% (954) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 62.20% (947) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 57.64% (942) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 62.30% (947) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 61.77% (939) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4116c | - | 0.0 | 67.37% (947) | putative membrane protein, MmpL |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 63.12% (941) | transmembrane transport protein MmpL5_2 |
M. smegmatis MC2 155 | MSMEG_0381 | - | 0.0 | 67.47% (959) | Mmp14a protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 64.56% (948) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 56.75% (941) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 58.93% (935) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDT--HTKPPFVARMIHRFAVPIILVWLAIAVTVSVFI MMAR_0771|M.marinum_M ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFI Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Mflv_4418|M.gilvum_PYR-GCK ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAV Mvan_1936|M.vanbaalenii_PYR-1 ---------------MADAGRSGIGRIIHLLAVPIVLGWIALTVLTNVAV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV MAB_4116c|M.abscessus_ATCC_199 ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV MSMEG_0381|M.smegmatis_MC2_155 --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV MAV_3248|M.avium_104 --------MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGV . : :*: :* ::* *: : . . : MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGDKP MMAR_0771|M.marinum_M PSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGKDA Mb0458c|M.bovis_AF2122/97 PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP Mflv_4418|M.gilvum_PYR-GCK PSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSAMVVLEGEQP Mvan_1936|M.vanbaalenii_PYR-1 PSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFDSDSSAMVVLEGEQP MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQEP MAB_4116c|M.abscessus_ATCC_199 PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGEGT MSMEG_0381|M.smegmatis_MC2_155 PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQEP TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQEP MAV_3248|M.avium_104 PSLEQVEAEHAVSLSPIGAPSFKAMERLGEDFKETNTGALAMILLEGQQQ * ** * :::.: . **: :* ::* * * :: : ::::**. MLBr_02378|M.leprae_Br4923 LGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAYVQ MMAR_0771|M.marinum_M LGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAYVQ Mb0458c|M.bovis_AF2122/97 LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ Rv0450c|M.tuberculosis_H37Rv LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ Mflv_4418|M.gilvum_PYR-GCK LGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQ Mvan_1936|M.vanbaalenii_PYR-1 LGDAAHRYYDELIGKLEADTANVQHVADFWGDPLTASGAQSTDGKAAYVQ MUL_0757|M.ulcerans_Agy99 LGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAYVQ MAB_4116c|M.abscessus_ATCC_199 LGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAYVQ MSMEG_0381|M.smegmatis_MC2_155 LGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAYVQ TH_3056|M.thermoresistible__bu LGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAFVQ MAV_3248|M.avium_104 LGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAYVQ ** ** :** :: *. . ** : ::****** ..:* * ***:** MLBr_02378|M.leprae_Br4923 LSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMHHS MMAR_0771|M.marinum_M LNLAGNQGEPLANESVEAVRKIVKETP-APPGVTTYVTGAAALVSDMHSS Mb0458c|M.bovis_AF2122/97 LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS Rv0450c|M.tuberculosis_H37Rv LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS Mflv_4418|M.gilvum_PYR-GCK VYLQGNQGEPRANEAVAAVREIVDRTP-APPGIKAYVTGGAPLVADQHSA Mvan_1936|M.vanbaalenii_PYR-1 VYLQGNQGEPRANEAVAAVREIVDQTP-APPGLKAYVTGGAPLVADQHNA MUL_0757|M.ulcerans_Agy99 VKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQLA MAB_4116c|M.abscessus_ATCC_199 LNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMAES MSMEG_0381|M.smegmatis_MC2_155 INLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMGES TH_3056|M.thermoresistible__bu VNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAGDS MAV_3248|M.avium_104 VNLNGNAGAAAGDESVAAIRKLVQEAS-PPPGLKVYVTGPAPIVADMNIA : * * * :*:: *:: * * *: .:*** :.: :* : MLBr_02378|M.leprae_Br4923 GDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVAL MMAR_0771|M.marinum_M GDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVELTAARGVVAL Mb0458c|M.bovis_AF2122/97 GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV Rv0450c|M.tuberculosis_H37Rv GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV Mflv_4418|M.gilvum_PYR-GCK GDTSVLRVTLITIGVIAVMLLIVFRSVATMVLILFMVFAELGAARGIVAF Mvan_1936|M.vanbaalenii_PYR-1 GDKSVFRVTLITIGVIAVMLLLVFRSVATMVLILFMVFAELGAARGIVAF MUL_0757|M.ulcerans_Agy99 GDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAF MAB_4116c|M.abscessus_ATCC_199 GNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLVAF MSMEG_0381|M.smegmatis_MC2_155 GNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVSF TH_3056|M.thermoresistible__bu GTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAY MAV_3248|M.avium_104 GQKTVMLVTLASLIVIFVTLLLVYRSVITVILLLLIVGLELQIARGMVAL * :: : :. ** : **:.:* . ::* * :** *: MLBr_02378|M.leprae_Br4923 LGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAF MMAR_0771|M.marinum_M LGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEARQAGEDKETAF Mb0458c|M.bovis_AF2122/97 LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY Rv0450c|M.tuberculosis_H37Rv LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY Mflv_4418|M.gilvum_PYR-GCK LADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY Mvan_1936|M.vanbaalenii_PYR-1 LANAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY MUL_0757|M.ulcerans_Agy99 LGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAY MAB_4116c|M.abscessus_ATCC_199 LGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRESAY MSMEG_0381|M.smegmatis_MC2_155 LALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQAY TH_3056|M.thermoresistible__bu LGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAY MAV_3248|M.avium_104 LGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEARQAGESREEAF *. :**:*:...**. **:.***.** ******* .:.:: *: MLBr_02378|M.leprae_Br4923 YTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAV MMAR_0771|M.marinum_M YTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAVMV Mb0458c|M.bovis_AF2122/97 YTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVAV Rv0450c|M.tuberculosis_H37Rv YTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAV Mflv_4418|M.gilvum_PYR-GCK YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIA Mvan_1936|M.vanbaalenii_PYR-1 YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVMA MUL_0757|M.ulcerans_Agy99 YTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAT MAB_4116c|M.abscessus_ATCC_199 YTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAVAV MSMEG_0381|M.smegmatis_MC2_155 YTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAV TH_3056|M.thermoresistible__bu FTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVAV MAV_3248|M.avium_104 YTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAVLV :* : .. :*:*.** **:** ** *:*:*:*:.:*:* *:* :.* . MLBr_02378|M.leprae_Br4923 ALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCA MMAR_0771|M.marinum_M ALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRWPLPVLAATLA Mb0458c|M.bovis_AF2122/97 ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA Rv0450c|M.tuberculosis_H37Rv ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA Mflv_4418|M.gilvum_PYR-GCK ALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA Mvan_1936|M.vanbaalenii_PYR-1 ALTLGPAVVAIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA MUL_0757|M.ulcerans_Agy99 ALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAVA MAB_4116c|M.abscessus_ATCC_199 ALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAATVA MSMEG_0381|M.smegmatis_MC2_155 ALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATIA TH_3056|M.thermoresistible__bu ALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAVA MAV_3248|M.avium_104 ALTLGPALLAAGARFG-LFEPRRAVSARRWRRIGTAIVRWPAPILIATLA **** ** : *** ::*:* : **::*. :**** *:* : * MLBr_02378|M.leprae_Br4923 IAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PEIL MMAR_0771|M.marinum_M VALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFSQARMK-PDIL Mb0458c|M.bovis_AF2122/97 IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL Rv0450c|M.tuberculosis_H37Rv IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL Mflv_4418|M.gilvum_PYR-GCK LALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQHFGSARMN-PELL Mvan_1936|M.vanbaalenii_PYR-1 LALVGLVALPGYKTNYDSRDYLPEDVPANVGYAVADRHFGSARMN-PELL MUL_0757|M.ulcerans_Agy99 LALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PEVL MAB_4116c|M.abscessus_ATCC_199 VALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPDIL MSMEG_0381|M.smegmatis_MC2_155 VAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDIL TH_3056|M.thermoresistible__bu LSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDVV MAV_3248|M.avium_104 VSLVGLLALPNYRPSYDDQKFIPDSIPANVGYAAAARHFPGQRMQMPEIL ::::**::**.*...* ::* :**. * .* :** * *::: MLBr_02378|M.leprae_Br4923 MIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSIP MMAR_0771|M.marinum_M MIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTSIP Mb0458c|M.bovis_AF2122/97 MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP Rv0450c|M.tuberculosis_H37Rv MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP Mflv_4418|M.gilvum_PYR-GCK MVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIP Mvan_1936|M.vanbaalenii_PYR-1 MVESDHDLRNPADFLVIDKIAKAIFRVPGVARVQTITRPDGKPIKHTTIP MUL_0757|M.ulcerans_Agy99 MVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSIP MAB_4116c|M.abscessus_ATCC_199 LIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSSVP MSMEG_0381|M.smegmatis_MC2_155 LVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP TH_3056|M.thermoresistible__bu LIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTIP MAV_3248|M.avium_104 LVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTTIP ::::::*:**.:*:*:::::*: :: * *:: **::***:* :.*:::* MLBr_02378|M.leprae_Br4923 FQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLTE MMAR_0771|M.marinum_M FQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQLAN Mb0458c|M.bovis_AF2122/97 FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS Rv0450c|M.tuberculosis_H37Rv FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS Mflv_4418|M.gilvum_PYR-GCK FQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSA Mvan_1936|M.vanbaalenii_PYR-1 FQMSMRSTTSRLNEKYMQDRMADMLVQADAMQTNVDTMTKMQSLMTQMSA MUL_0757|M.ulcerans_Agy99 FLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMAD MAB_4116c|M.abscessus_ATCC_199 FMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQMVD MSMEG_0381|M.smegmatis_MC2_155 FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVA TH_3056|M.thermoresistible__bu FMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMVA MAV_3248|M.avium_104 WIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMRELVA : :** : . : : .:* *.: : : : :* * : MLBr_02378|M.leprae_Br4923 NTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPICW MMAR_0771|M.marinum_M NTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWEKHCYDIPICS Mb0458c|M.bovis_AF2122/97 TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW Rv0450c|M.tuberculosis_H37Rv TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW Mflv_4418|M.gilvum_PYR-GCK TTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVRNYFYWEPHCYDIPVCW Mvan_1936|M.vanbaalenii_PYR-1 ATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPVRNYFYWEPHCYNIPVCA MUL_0757|M.ulcerans_Agy99 VTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVCW MAB_4116c|M.abscessus_ATCC_199 TTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPICW MSMEG_0381|M.smegmatis_MC2_155 TTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLCW TH_3056|M.thermoresistible__bu TTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPICW MAV_3248|M.avium_104 TTHHMVQTTHEMQEITGELRDHISDFEDFWRPLRSYFYWEKHCYDIPICF ** : :*: : :::** **:*.*::*: **:.**:* MLBr_02378|M.leprae_Br4923 SFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMESM MMAR_0771|M.marinum_M SFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETFPPMIETMESM Mb0458c|M.bovis_AF2122/97 SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM Rv0450c|M.tuberculosis_H37Rv SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM Mflv_4418|M.gilvum_PYR-GCK TMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRSM Mvan_1936|M.vanbaalenii_PYR-1 TMRSVFDTLDGINPLTDDIQELIPDLERLDALMPQLIALLPSQIESMRNM MUL_0757|M.ulcerans_Agy99 SLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKSM MAB_4116c|M.abscessus_ATCC_199 SIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMKST MSMEG_0381|M.smegmatis_MC2_155 SIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLENS TH_3056|M.thermoresistible__bu SIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMESS MAV_3248|M.avium_104 SLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQIPPMIETMSGM ::**:** ***:: : : : :: : .:* ::**: :* * : . MLBr_02378|M.leprae_Br4923 RTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKN MMAR_0771|M.marinum_M RLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVFKN Mb0458c|M.bovis_AF2122/97 RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN Rv0450c|M.tuberculosis_H37Rv RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN Mflv_4418|M.gilvum_PYR-GCK QAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDN Mvan_1936|M.vanbaalenii_PYR-1 QSMMLTMYQSQKGLQDQMASQSEDADAMGEAFDDSMNDDSFYLPPEAFDN MUL_0757|M.ulcerans_Agy99 KAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNN MAB_4116c|M.abscessus_ATCC_199 RESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVLKN MSMEG_0381|M.smegmatis_MC2_155 RSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILEN TH_3056|M.thermoresistible__bu RTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALEN MAV_3248|M.avium_104 RTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGIING : :* : : * * .:. :**:*** : ********* :.. MLBr_02378|M.leprae_Br4923 TD-FKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALK MMAR_0771|M.marinum_M ED-FKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEESLK Mb0458c|M.bovis_AF2122/97 KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK Rv0450c|M.tuberculosis_H37Rv KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK Mflv_4418|M.gilvum_PYR-GCK DD-FKRGMENFISPDGRSVRFIISHEGDPATVEGISEVVPIKTAAKEAIK Mvan_1936|M.vanbaalenii_PYR-1 DD-FKRGIENFISPDGKSVRFIIAHEGDPATVEGISRVLPIKTAAKEAIK MUL_0757|M.ulcerans_Agy99 PD-FKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIK MAB_4116c|M.abscessus_ATCC_199 KD-FQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEALK MSMEG_0381|M.smegmatis_MC2_155 ED-FKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALK TH_3056|M.thermoresistible__bu KD-FQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALK MAV_3248|M.avium_104 SDSFKRVEKVFMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEESLK * *:* : *:*.**: *::: :.*** : *: : * **:*::* MLBr_02378|M.leprae_Br4923 GTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRA MMAR_0771|M.marinum_M GTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIFIIMLILTRA Mb0458c|M.bovis_AF2122/97 GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA Rv0450c|M.tuberculosis_H37Rv GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA Mflv_4418|M.gilvum_PYR-GCK GTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLIFVIMLVITRS Mvan_1936|M.vanbaalenii_PYR-1 GTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGIAAVTLIFVIMLIITRS MUL_0757|M.ulcerans_Agy99 GTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRS MAB_4116c|M.abscessus_ATCC_199 GTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMTRS MSMEG_0381|M.smegmatis_MC2_155 GTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRS TH_3056|M.thermoresistible__bu GTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRS MAV_3248|M.avium_104 GTPLENSKIYLTGTAAITKDLVDGSKFDLLIAGVSALCLIFIIMLIMTRS ***** : : : *:.: :: :* **:**.:::: ***:**:.:**: MLBr_02378|M.leprae_Br4923 FVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVG MMAR_0771|M.marinum_M FVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLAVG Mb0458c|M.bovis_AF2122/97 FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG Rv0450c|M.tuberculosis_H37Rv FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG Mflv_4418|M.gilvum_PYR-GCK VVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVG Mvan_1936|M.vanbaalenii_PYR-1 VVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVG MUL_0757|M.ulcerans_Agy99 VVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVG MAB_4116c|M.abscessus_ATCC_199 LVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLAVG MSMEG_0381|M.smegmatis_MC2_155 FIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVG TH_3056|M.thermoresistible__bu VIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVG MAV_3248|M.avium_104 FIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLAVG .:** ****** :*******:***:**:: : ::: **. :**:***** MLBr_02378|M.leprae_Br4923 SDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVV MMAR_0771|M.marinum_M SDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASMAV Mb0458c|M.bovis_AF2122/97 SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV Rv0450c|M.tuberculosis_H37Rv SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV Mflv_4418|M.gilvum_PYR-GCK SDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAF Mvan_1936|M.vanbaalenii_PYR-1 SDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVVTSAGLVFAFTMASFAF MUL_0757|M.ulcerans_Agy99 ADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAV MAB_4116c|M.abscessus_ATCC_199 SDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSMIV MSMEG_0381|M.smegmatis_MC2_155 SDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV TH_3056|M.thermoresistible__bu SDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIV MAV_3248|M.avium_104 SDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAMVV :****:**:*:*:*: .*::*****:*.*:* *** ****** ** :: . MLBr_02378|M.leprae_Br4923 SDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRP MMAR_0771|M.marinum_M SDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFWWPMRVRTRP Mb0458c|M.bovis_AF2122/97 SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP Rv0450c|M.tuberculosis_H37Rv SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP Mflv_4418|M.gilvum_PYR-GCK SDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKFRSAA Mvan_1936|M.vanbaalenii_PYR-1 SDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKVRSHA MUL_0757|M.ulcerans_Agy99 SELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP MAB_4116c|M.abscessus_ATCC_199 SDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSPRP MSMEG_0381|M.smegmatis_MC2_155 SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRP TH_3056|M.thermoresistible__bu SDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRP MAV_3248|M.avium_104 SDLRSIGQVGTTIGLGLLFDTLIVRAFMTPSVAALLGRWFWWPQLVRPRP *:* :.******.:******::**:** *::**:**:***** . MLBr_02378|M.leprae_Br4923 LLTVAAPVGLP-PDRSLVYSD---- MMAR_0771|M.marinum_M ARTPSSPTADPEPDRALAMSGER-- Mb0458c|M.bovis_AF2122/97 ARTPTVPSETQPAGRPLAMSSDRLG Rv0450c|M.tuberculosis_H37Rv ARTPTVPSETQPAGRPLAMSSDRLG Mflv_4418|M.gilvum_PYR-GCK SERRLARIGVQPATAGR-------- Mvan_1936|M.vanbaalenii_PYR-1 SQRRLAALNH--------------- MUL_0757|M.ulcerans_Agy99 APQPWPTPAPTPPPATTSV------ MAB_4116c|M.abscessus_ATCC_199 VGAVRGWRGPR-LVRSVLQRN---- MSMEG_0381|M.smegmatis_MC2_155 ASAMLRSVGPRPLVRSLLLRD---- TH_3056|M.thermoresistible__bu ASAMLRPVGPRPLVRSLLLRD---- MAV_3248|M.avium_104 ASTMLRPTGPRPLVRSLLLKQPQ--