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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3377 | - | - | 100% (422) | putative MorD |
| M. thermoresistible (build 8) | TH_3048 | - | 9e-80 | 40.14% (416) | PUTATIVE putative phosphomannomutase/phosphoglucomutase |
| M. thermoresistible (build 8) | TH_4410 | - | 7e-49 | 31.22% (394) | PUTATIVE putative cytochrome P450 107B1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2291c | cyp128 | 2e-94 | 45.26% (422) | cytochrome P450 128 |
| M. gilvum PYR-GCK | Mflv_1321 | - | 1e-55 | 34.54% (388) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv2268c | cyp128 | 2e-94 | 45.26% (422) | cytochrome P450 128 |
| M. leprae Br4923 | MLBr_02088 | - | 2e-42 | 29.72% (397) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1216c | - | 4e-44 | 33.25% (403) | cytochrome P450 |
| M. marinum M | MMAR_4833 | cyp123B1 | 3e-49 | 36.44% (365) | cytochrome P450 123B1 Cyp123B1 |
| M. avium 104 | MAV_1404 | - | 3e-47 | 33.33% (393) | putative cytochrome P450 130 |
| M. smegmatis MC2 155 | MSMEG_5038 | - | 2e-50 | 33.33% (390) | putative cytochrome P450 123 |
| M. ulcerans Agy99 | MUL_3131 | cyp144A4 | 8e-44 | 34.85% (307) | cytochrome P450 144A4 Cyp144A4 |
| M. vanbaalenii PYR-1 | Mvan_5481 | - | 1e-51 | 34.29% (385) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2291c|M.bovis_AF2122/97 MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSG
Rv2268c|M.tuberculosis_H37Rv MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSG
TH_3377|M.thermoresistible__bu MSTT----------LRLVGDAIR-----------MNVAAAVRTRRRGYDG
MAB_1216c|M.abscessus_ATCC_199 ------------------------------------MTVAETSAVP----
MMAR_4833|M.marinum_M -----------------------------------MWQETLMSTVQ----
MAV_1404|M.avium_104 -------------------------------------MSHNVP-------
MSMEG_5038|M.smegmatis_MC2_155 -------------------------------------MGADLSHPA----
Mflv_1321|M.gilvum_PYR-GCK ------------------------------------MPPPLHSPAF----
Mvan_5481|M.vanbaalenii_PYR-1 ---------------------------------MSRLSNPLHSPAF----
MLBr_02088|M.leprae_Br4923 ----------MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQM----
MUL_3131|M.ulcerans_Agy99 ----------------------------------MKVASDAMTFFG----
Mb2291c|M.bovis_AF2122/97 GIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLT
Rv2268c|M.tuberculosis_H37Rv GIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLT
TH_3377|M.thermoresistible__bu --------WTGAIN-----------------------------------T
MAB_1216c|M.abscessus_ATCC_199 -------------------------------------------------L
MMAR_4833|M.marinum_M -------------------------------------------------L
MAV_1404|M.avium_104 -------------------------------------------------V
MSMEG_5038|M.smegmatis_MC2_155 -------------------------------------------------V
Mflv_1321|M.gilvum_PYR-GCK -------------------------------------------------Y
Mvan_5481|M.vanbaalenii_PYR-1 -------------------------------------------------Y
MLBr_02088|M.leprae_Br4923 -------------------------------------------------L
MUL_3131|M.ulcerans_Agy99 --------------------------------------------------
Mb2291c|M.bovis_AF2122/97 DFDPFDPAIAADPYPHYRELLAGERVQYNP-----KRDVYILSRYADVRE
Rv2268c|M.tuberculosis_H37Rv DFDPFDPAIAADPYPHYRELLAGERVQYNP-----KRDVYILSRYADVRE
TH_3377|M.thermoresistible__bu DYDPQDPATAAHPFDAYRALHRGGRVHYNP-----RRATFIVARLEDVRA
MAB_1216c|M.abscessus_ATCC_199 VFDPYDYDFHEDPYPYYRRLRDEAPLYRND-----DLKFWALSRHHDVLQ
MMAR_4833|M.marinum_M RYDPFDPEIQDDPYPVYRQLRDDAPVYHAT-----DTNTWVLSRHADVIS
MAV_1404|M.avium_104 AFELPNADTWADPWPMYRALRDHDPVHHVVPPKRPEHDYYVLSRHADVWA
MSMEG_5038|M.smegmatis_MC2_155 AFELANADTWADPWDMYTALRDHDPVHHVVPPERPHHDYFVLSRHADIWA
Mflv_1321|M.gilvum_PYR-GCK AG---------DPFPAYRELRATDPVTWN-----EEHGFWALLKYEDIR-
Mvan_5481|M.vanbaalenii_PYR-1 AG---------DPFPVYRELRATDPVCWN-----DEHEFWALLKYEDIR-
MLBr_02088|M.leprae_Br4923 LLRLIDPGTRADPFPVYRALIDYGPMQLPG---MPLTVFSSFSDCDEALR
MUL_3131|M.ulcerans_Agy99 ------TESLQNPYPLYERMRAEGPVHRIA-----DSEFYAVCGWDAVND
.*: * : : .
Mb2291c|M.bovis_AF2122/97 AARNHDTLSSARGVTFSR--------GWLPFL-------PTSDPPAHTRM
Rv2268c|M.tuberculosis_H37Rv AARNHDTLSSARGVTFSR--------GWLPFL-------PTSDPPAHTRM
TH_3377|M.thermoresistible__bu ALRDTDQVTSCQGVTRWR--------MSAPLA-------VLTDGEEHARL
MAB_1216c|M.abscessus_ATCC_199 GFRNSEALSNANGVSMDKASFGPH-AKLVMSF-------LAMDDPEHLRL
MMAR_4833|M.marinum_M ALLDHHSYSSVDGVFPTPPGSTFR-ESLLPMM-------ILMDPPRHDQL
MAV_1404|M.avium_104 AARDHETFSSAKGLTVNYDDLELIGLQDNPPF-------VMQDPPVHTEF
MSMEG_5038|M.smegmatis_MC2_155 AARDHETYSSAQGLTVNYGELELIGLADNPPF-------VMQDPPTHTEF
Mflv_1321|M.gilvum_PYR-GCK -YVSTNPALFSSARGITVPDPAIENPVMEGSL-------IFTDPPRHRRL
Mvan_5481|M.vanbaalenii_PYR-1 -YVSTNPALFSSARGVTVPDPALENPVMEGSL-------IFTDPPRHRQL
MLBr_02088|M.leprae_Br4923 HPLSASDRLKATLAQQAIAAGAEPRPFYASSF-------MFLDPPDHTRL
MUL_3131|M.ulcerans_Agy99 AISRPGDFSSNLTATMTYSPDGKVAAFEMDQLGGPTHVLATADDPAHAVH
* *
Mb2291c|M.bovis_AF2122/97 RKQLAPGMARGALETWRPMVDQLARELVGGLLTQTPA---DVVSTVAAPM
Rv2268c|M.tuberculosis_H37Rv RKQLAPGMARGALETWRPMVDQLARELVGGLLTQTPA---DVVSTVAAPM
TH_3377|M.thermoresistible__bu RKQVQPGFSKGAMESWQEIVEKLAVEHVTDLLANPGC---DVVQRLAIPM
MAB_1216c|M.abscessus_ATCC_199 RALVSKGFTPRRIRELEGQVVALARTHLDRALANASDRSFDFIAEYAGKL
MMAR_4833|M.marinum_M RALVSKAFTPRRIAALTSAIEDLA-DHLTGGLIQEAG-SADFVADFAAVL
MAV_1404|M.avium_104 RKLVSRGFTPRQVEAVEPKVRDFVVERIERLRAAGGG---DIVAELFKPL
MSMEG_5038|M.smegmatis_MC2_155 RKLVSRGFTPRQVEAVEPQVREFVVERLERLRAEGGG---DIVAELFKPL
Mflv_1321|M.gilvum_PYR-GCK RKLINSGFTRRQVAILEPKLRAFARTALD---AIDPAGGTEFAERIAAPL
Mvan_5481|M.vanbaalenii_PYR-1 RKLINSGFTRRQVAILEPKLRAFARAALD---AIDPS-ATEFAEQVAAPL
MLBr_02088|M.leprae_Br4923 RKLVSKAFAPKVVQALEGDIAALVDSLLD---KGAAAGQFDVIADLAFPL
MUL_3131|M.ulcerans_Agy99 RKLLVRHLAARRIRSLERFVSETAERLWFDGLQGGRI---EWMDAIANRL
* : :: : : . : :
Mb2291c|M.bovis_AF2122/97 PMRAITSVLGVDGPDEAAFCRLSNQAVRITDVALSAS------GLISLVQ
Rv2268c|M.tuberculosis_H37Rv PMRAITSVLGVDGPDEAAFCRLSNQAVRITDVALSAS------GLISLVQ
TH_3377|M.thermoresistible__bu PIRLIAGILGVPDTDLDDFRRWSERGVGLMEVKPTAIT----EAARSAIA
MAB_1216c|M.abscessus_ATCC_199 PMDVISELMGVPESDRARIRELADGVMHREDGLA-------DVPPEAIQA
MMAR_4833|M.marinum_M PAMVIADLLGVPREDRTQFRQWSNALVQSNPTHG-------ETG-EALAA
MAV_1404|M.avium_104 PSMVVAHYLGVPEEDRAQFDGWTEAIVAANTADGGV----AGALGSAGDA
MSMEG_5038|M.smegmatis_MC2_155 PSMVVAHYLGVPEADRAQFDGWTEAIVAANSEAG-------SALG-AGDA
Mflv_1321|M.gilvum_PYR-GCK PTRMIAELLGAPDEDWEQFRRWSDAAVGMDD---------PDVELDTFTA
Mvan_5481|M.vanbaalenii_PYR-1 PTRMIAELLGAPDEDWEQFRTWSDATVGMDD---------PDVELDTFAA
MLBr_02088|M.leprae_Br4923 AVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRA
MUL_3131|M.ulcerans_Agy99 PMMVVAELIGLPDADIAQLVQWGYGATQLLEGLVDQ-----DQLADAGIA
. : :* * :
Mb2291c|M.bovis_AF2122/97 GFAGFRRLRALFTHRRDNGLLRECTVLGKLATH---AEQGRLSDDELFFF
Rv2268c|M.tuberculosis_H37Rv GFAGFRRLRALFTHRRDNGLLRECTVLGKLATH---AEQGRLSDDELFFF
TH_3377|M.thermoresistible__bu MASLCRYLRQQFAHG---GLKGSDTVLGRLLAH---NTDGSLTDQQLLLV
MAB_1216c|M.abscessus_ATCC_199 SFDLMTYYIEMVRERRR---RPTEDLTSALLQA--EIDGDRLTDEEVLAF
MMAR_4833|M.marinum_M AAAIYGYFTDFLADRRR---QPRDDLMSALVCA--EIDGKHLSDDELLGF
MAV_1404|M.avium_104 VTSMMAYFTGLIERRRT---DPEDDTISHLVSAGVGADGDIAGTLSVLAF
MSMEG_5038|M.smegmatis_MC2_155 VMSMTGYFAELIERRRR---EPGDDTISHLVAA--GADDEAVDVLSILAF
Mflv_1321|M.gilvum_PYR-GCK MGELYQYFEKLIALRRNGALRDSDDLLSVLVAA--EVDGVRLSDQDLLQF
Mvan_5481|M.vanbaalenii_PYR-1 MGELYQYFEAQIARRRDGTLRDSDDLLSVLVAA--EVDGVRLTDQDLLQF
MLBr_02088|M.leprae_Br4923 GVWLRDYLEQLVKCRRG---TPGEDLISRLIEL--DESGDQLTEEEIIAT
MUL_3131|M.ulcerans_Agy99 VMQLSGCITEQFARAAAD---PQENLLGELATA---CAAGELDSLTANLM
. . *
Mb2291c|M.bovis_AF2122/97 AVLLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRF
Rv2268c|M.tuberculosis_H37Rv AVLLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRF
TH_3377|M.thermoresistible__bu AIHLLIAGNETTTNLLGGMFDTLAHRPDQYQLIRANPELIPIAVEEHLRF
MAB_1216c|M.abscessus_ATCC_199 LFLMVIAGNETTTKLLANAVYWGHRNPDQLATVHADHDRIPLWVEESLRY
MMAR_4833|M.marinum_M CLLLLIAGHETTSNLLANAAVVLADYRDTRRQLAGDESLLGAAVEELLRY
MAV_1404|M.avium_104 TFTMVTGGNDTTTGMLGGSMPLLHQRPDQRQRLVDEPELIPDAVEELLRL
MSMEG_5038|M.smegmatis_MC2_155 TFTMVTGGNDTTTGMLGGAVQLLQQHPDQRRVLTDDPDLIPDAVDEFLRL
Mflv_1321|M.gilvum_PYR-GCK CLLLLVAGNETTRNLIALGTLALIEHPQQFRLLREHPELIPTAVEEFLRY
Mvan_5481|M.vanbaalenii_PYR-1 CLLLLVAGNETTRNLVALGTLALIENPDQFRLLRQRRDLVPTAVEEMLRY
MLBr_02088|M.leprae_Br4923 CGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRY
MUL_3131|M.ulcerans_Agy99 MVMLFAAGGESTASLLGSAVWILATRPDIQQQVRDNPQLLGAFVEETLRY
:. .* ::* ::. . : . ::* **
Mb2291c|M.bovis_AF2122/97 ISPIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYE-DPDVFR
Rv2268c|M.tuberculosis_H37Rv ISPIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYE-DPDVFR
TH_3377|M.thermoresistible__bu TTPIQNLYRYTRTDYRIGDVVIPAGSRVLLSFGAANRDPSVFD-EPDDFR
MAB_1216c|M.abscessus_ATCC_199 DTSSQILARTVAEDITVYDTKIPAGDILLLLPGSANRDDRVFD-DADQYR
MMAR_4833|M.marinum_M DSPAQGLSRTLTRDVTVHGVRMSAGESVLLLFGSANRDERVFA-DPDVFD
MAV_1404|M.avium_104 TSPVQGLARTTTRDVTIGRTTIPAGRRVLLLYGSANRDERQYGPDAGELD
MSMEG_5038|M.smegmatis_MC2_155 TSPVQGLARTATRDVTIGDTTIPAGRKVLLLYGSGNRDEREFGPDAAQLD
Mflv_1321|M.gilvum_PYR-GCK TSPVANMTRCATRDVEMRGRLIREGQYVTMLYGSANRDEDIFGPTSEQLD
Mvan_5481|M.vanbaalenii_PYR-1 ASPVANMTRCATRDVDIRGRSIRAGQYVTMLYGSANRDKDVFGPTSEQFD
MLBr_02088|M.leprae_Br4923 DPAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYS-RPDEFD
MUL_3131|M.ulcerans_Agy99 EAPFRAHYRHVRNDTTLGGLTLPADSHLLLMWGAANRDPVQFD-APEEFR
.. * * : : . : : .:.*** : .
Mb2291c|M.bovis_AF2122/97 ADRNP-VGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPT
Rv2268c|M.tuberculosis_H37Rv ADRNP-VGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPT
TH_3377|M.thermoresistible__bu ADRDP-RKHVAFGYGAHMCLGAPLARMEAQAVLRQLVTRVANISPVGPTR
MAB_1216c|M.abscessus_ATCC_199 IGREIGAKLVSFGSGAHFCLGAHLARMEAKVALTELFTRISGYEIDERNS
MMAR_4833|M.marinum_M IGRKP-EHQVAFGRGIHFCLGASLARMEARIALRALLARVPNWEVDLERA
MAV_1404|M.avium_104 VARCP-RNILTFSHGAHHCLGAAAARMQSRVALTELLARCPDFEVDESGI
MSMEG_5038|M.smegmatis_MC2_155 VRRRP-RNILTFSHGAHFCLGAAAARMQSRVALTELLTRCPDFTVDLDAV
Mflv_1321|M.gilvum_PYR-GCK VTRNP-NPHLAFGCGEHSCLGAQLARLEARVLFEELLARFEHIEPAG-EV
Mvan_5481|M.vanbaalenii_PYR-1 ITRNP-NPHLAFGCGEHSCLGAQLARLEARVLFEELLNRFDHIELDG-DV
MLBr_02088|M.leprae_Br4923 PDRPS-SRHLAFAVGSHFCLGAALARLEATVTLSAISARFPQVQLAG-EL
MUL_3131|M.ulcerans_Agy99 LDRPGGKGHISFGKGAHFCVGAALARLEAQIVLRLLLERTTVIEAAD-VG
* ::*. * * * *: **::. : : .
Mb2291c|M.bovis_AF2122/97 WTTNAN-LRGLTRLRVAVTPRVAP-----------
Rv2268c|M.tuberculosis_H37Rv WTTNAN-LRGLTRLRVAVTPRVAP-----------
TH_3377|M.thermoresistible__bu WSTHSS-LHGPTRLPIRLTPA--------------
MAB_1216c|M.abscessus_ATCC_199 VRVHSSNVRGFAHLPMTVQLREGR-----------
MMAR_4833|M.marinum_M QRLRSGPIRGYLSLPISWSAN--------------
MAV_1404|M.avium_104 VWAGGNYVRRPLSVPIRVKS---------------
MSMEG_5038|M.smegmatis_MC2_155 VWAGGSYVRRPLSVPFRAGA---------------
Mflv_1321|M.gilvum_PYR-GCK LRMQATMVPGVRAMPVRLRAATDPRRAKARAG---
Mvan_5481|M.vanbaalenii_PYR-1 LRMQATMVPGVRQMPVRLSATAAEPRETGTAAVSV
MLBr_02088|M.leprae_Br4923 VYKPNVAMRGMSALPVQV-----------------
MUL_3131|M.ulcerans_Agy99 RWLPSMLVRRLENLELAVR----------------
: : .