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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2539 | - | - | 100% (411) | cytochrome P450 |
| M. thermoresistible (build 8) | TH_2856 | - | e-130 | 59.39% (394) | PUTATIVE cytochrome P450 |
| M. thermoresistible (build 8) | TH_2585 | - | e-128 | 58.65% (399) | PUTATIVE putative cytochrome P450 123 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0789c | cyp123 | 2e-76 | 41.46% (398) | cytochrome P450 123 |
| M. gilvum PYR-GCK | Mflv_2477 | - | 1e-133 | 61.81% (398) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv0766c | cyp123 | 2e-76 | 41.46% (398) | cytochrome P450 123 |
| M. leprae Br4923 | MLBr_02088 | - | 1e-47 | 34.86% (370) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1216c | - | 4e-74 | 40.30% (402) | cytochrome P450 |
| M. marinum M | MMAR_4733 | cyp190A3 | 1e-130 | 57.64% (399) | cytochrome P450 190A3 Cyp190A3 |
| M. avium 104 | MAV_0916 | - | 1e-125 | 56.25% (400) | cytochrome P450 monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4818 | - | 1e-127 | 58.19% (397) | putative cytochrome P450 123 |
| M. ulcerans Agy99 | MUL_0475 | cyp123A3 | 2e-75 | 41.19% (403) | cytochrome P450 123A3 Cyp123A3 |
| M. vanbaalenii PYR-1 | Mvan_2001 | - | 1e-121 | 57.18% (397) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0789c|M.bovis_AF2122/97 --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
Rv0766c|M.tuberculosis_H37Rv --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
MAB_1216c|M.abscessus_ATCC_199 --------------------------MTVAETSAVPLVFDPYDYDFHEDP
MUL_0475|M.ulcerans_Agy99 --------------------------MSVHVGGPE-LVLDPYDYDFHEDP
MAV_0916|M.avium_104 --------------------------MTKPKL-----VFDPYSEDYFNNP
MSMEG_4818|M.smegmatis_MC2_155 --------------------------MTTPQM-----IFDPFSEQYFENP
Mflv_2477|M.gilvum_PYR-GCK --------------------------MTATDL-----VFDPFSEEFFNGP
Mvan_2001|M.vanbaalenii_PYR-1 --------------------------MAVVDVGRDPVVFDPFSEEFYRDP
MMAR_4733|M.marinum_M --------------------------MTTSKV-----VFDPFSEEFFNGP
TH_2539|M.thermoresistible__bu ------------------------VSVQVDKPVDGPVQFDPFSEDYFNGP
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
: . .*
Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
Rv0766c|M.tuberculosis_H37Rv YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
MAB_1216c|M.abscessus_ATCC_199 YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK
MUL_0475|M.ulcerans_Agy99 YPYYRRLRNEAPLYHNQELGFWALSRRRDVHQGFRNSTTLSNRDGVSLDP
MAV_0916|M.avium_104 YEIYRRMREEAPLYYDEKEDFYALTRHVDVAAAFKDYETYSSARGCDLAM
MSMEG_4818|M.smegmatis_MC2_155 FDIYRQMRDDAPLYYDSEQDFYALSRHEDVAAALKDHEAFSSSRGCDLAM
Mflv_2477|M.gilvum_PYR-GCK WEIYRRMRSEAPVYYNAEYDFYALSRHEDVAAAYKDFETYSSAYGLDLAT
Mvan_2001|M.vanbaalenii_PYR-1 QGCYPRLRAEAPVYYNATYDFYALSRHADVAAGLKDFATYSSAYGVDLGM
MMAR_4733|M.marinum_M WETYRRMQAEAPVYYSEQYDFYALTRHADVAAGLKNFERYSSAYGIDLSM
TH_2539|M.thermoresistible__bu WQTYRRLRDEAPVYYNAEWDFWALSRFDDVAAATKDHETFSSAKGATLDM
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
* : .*: : ..: * . :. *. :
Mb0789c|M.bovis_AF2122/97 SSRTSEA----YRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
Rv0766c|M.tuberculosis_H37Rv SSRTSEA----YRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
MAB_1216c|M.abscessus_ATCC_199 ASFGPHA----KLVMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA
MUL_0475|M.ulcerans_Agy99 VSRGPHA----TKTMSFLAIDDPAHLRLRTLVSKGFTPRRIRELEPRVTE
MAV_0916|M.avium_104 VRRGIS-----PEQKSIIFMDPPEHRHMRSLLNKAFTPRAIQSQRETIIE
MSMEG_4818|M.smegmatis_MC2_155 VK-GDE-----PPQKSIIFMDPPEHRHMRSLLNKAFTPRAVQAQRDTVVE
Mflv_2477|M.gilvum_PYR-GCK VRSDEP-----IPAKMIIIMDPPEHRQMRSLVNKVFTPRAIEALRPMVTE
Mvan_2001|M.vanbaalenii_PYR-1 VRRGEK-----VPAKMIISIDPPEHRAMRSLVNKVFTPRAIEALRTMVTD
MMAR_4733|M.marinum_M VRSGQ------KPPQSIIFMDPPDHRHMRSLLNKVFTPRAIQAQRQTVID
TH_2539|M.thermoresistible__bu VKAPEQSI---PVPKVIISMDPPEHNRMRKLVSSVFTPRAVAALEDMVRE
MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA
:: :* * * :* *:.. *:*: : . :
Mb0789c|M.bovis_AF2122/97 LARIHLDSALQTES----FDFVAEFAGKLPMDVISELIGVPDTDRARIR-
Rv0766c|M.tuberculosis_H37Rv LARIHLDSALQTES----FDFVAEFAGKLPMDVISELIGVPDTDRARIR-
MAB_1216c|M.abscessus_ATCC_199 LARTHLDRALANASD-RSFDFIAEYAGKLPMDVISELMGVPESDRARIR-
MUL_0475|M.ulcerans_Agy99 LAVAHLDTMLDMAGGSQTVDYVAEFAGKLPMDVISELMGVPVADRDQIR-
MAV_0916|M.avium_104 VVDKYLS-AADPDN----FDVVQDFSGPFPVEVITRMAGVPEEYRQQVR-
MSMEG_4818|M.smegmatis_MC2_155 QVEHYLG-QIDSDE----FDVVQDFSGPFPVEVITRMAGVEPEYRQQVR-
Mflv_2477|M.gilvum_PYR-GCK TIDRYLS-QVDRDS----FDVVQDFSALFPVQVITQMLGVPEEYRKQVG-
Mvan_2001|M.vanbaalenii_PYR-1 TVTRFLS-AVRGDS----FDVVQDFSVYFPVDVITQMLGVPEKYRQQVR-
MMAR_4733|M.marinum_M KIDKYLG-ALDPEG----FDAVQEFSGPFPVEVITTMLGVPERHAQQVR-
TH_2539|M.thermoresistible__bu KIYRLIE-RLDPAAG---FDAVADFSAIFPNQVITTMLGVPEEDREQIR-
MLBr_02088|M.leprae_Br4923 LVDSLLDKGAAAGQ----FDVIADLAFPLAVAVICRLLGVPYEDAPEFGR
: .* : : : :. ** : ** ..
Mb0789c|M.bovis_AF2122/97 ------ALADAVLHREDGVADVPPPAMAASIELMRYYADLIAEFRRRPAN
Rv0766c|M.tuberculosis_H37Rv ------ALADAVLHREDGVADVPPPAMAASIELMRYYADLIAEFRRRPAN
MAB_1216c|M.abscessus_ATCC_199 ------ELADGVMHREDGLADVPPEAIQASFDLMTYYIEMVRERRRRPTE
MUL_0475|M.ulcerans_Agy99 ------AMADGVMHREDGVTDVPASAIEASINLIVYYQQMIAERRKKPSD
MAV_0916|M.avium_104 ------HWIDTSLHHEPGQIEVSEAGMQANIDTAMYYFGLVQERRQNPQD
MSMEG_4818|M.smegmatis_MC2_155 ------HWIDTSLSREPGQVAYSEAGMKANIDTAMYYYSLVQKRRENPQD
Mflv_2477|M.gilvum_PYR-GCK ------EWVDTSLRREPGQIDMSDEGMQAVGELMGLYYSIIQQRREDPRD
Mvan_2001|M.vanbaalenii_PYR-1 ------LWIDESLHREPGQIDMSEAGMQAMAETWLMYYDLIKQRRADPRD
MMAR_4733|M.marinum_M ------HWIDESLTREPGQVEVGEQGMQANINTAMLYYDLVKQRRDDPRD
TH_2539|M.thermoresistible__bu ------RWLDLLIERKPGQIHITDEGYEASVATGMYYYGLVQKRRAAPQD
MLBr_02088|M.leprae_Br4923 VSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGE
* : * :: * * :
Mb0789c|M.bovis_AF2122/97 NLTSALLAAELDG-----DRLSDQEIMAFLFLMVIAGNETTTKLLANAVY
Rv0766c|M.tuberculosis_H37Rv NLTSALLAAELDG-----DRLSDQEIMAFLFLMVIAGNETTTKLLANAVY
MAB_1216c|M.abscessus_ATCC_199 DLTSALLQAEIDG-----DRLTDEEVLAFLFLMVIAGNETTTKLLANAVY
MUL_0475|M.ulcerans_Agy99 DLTSALLAADVDG-----DRLTDEEVLGFMFLMVIAGNETTTKLLANAAF
MAV_0916|M.avium_104 DMISRLIAAEIPGENGQMRKLDDIEITGFATLLGGAGAETVTKLLGNAAV
MSMEG_4818|M.smegmatis_MC2_155 DMISRLIAAEIPGENGEMRRLDDVEITGFATLLGGAGAETVTKLIGTAMV
Mflv_2477|M.gilvum_PYR-GCK DMFSRLIAAEITREDGEKESLDDFEIAGFATLLGGAGAETVTKLVGNAAV
Mvan_2001|M.vanbaalenii_PYR-1 DMISALIAAEVEREDGTVDRLKDSEIAGFATLLGGAGAETVTKLVGSAVV
MMAR_4733|M.marinum_M DLFTKLINAEIEREDGQVTNLDDLEIAGFATLLGGAGAETVTKLVGNAAV
TH_2539|M.thermoresistible__bu DMISRLIETEIER-DGRIEKLTDVDITGFATMLGGAGAETVTKLIGNAVV
MLBr_02088|M.leprae_Br4923 DLISRLIELDESG-----DQLTEEEIIATCGLLLVAGHETTVNLIANAVL
:: : *: : * : :: . :: ** **..:*:..*
Mb0789c|M.bovis_AF2122/97 WAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTT
Rv0766c|M.tuberculosis_H37Rv WAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTT
MAB_1216c|M.abscessus_ATCC_199 WGHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAEDITVYDTK
MUL_0475|M.ulcerans_Agy99 WGHKNTDQLTPIYADLSRVPLWVEETLRYDTSSQILARTVVGELTLYDTT
MAV_0916|M.avium_104 IFARHPDQWQKLQDDRDKIPGAVEELLRYEGPVQYNVRYTLKEAHVSGGV
MSMEG_4818|M.smegmatis_MC2_155 TFAKFPDQWQKLLDDRSKVPAAVEELLRYEGPVQYNVRYTLKEARVPSGT
Mflv_2477|M.gilvum_PYR-GCK TFARHPDQWQKLLDDRSKIPAAVEELLRFEAPNQYNVRRSMKDVELHGVT
Mvan_2001|M.vanbaalenii_PYR-1 TFARHPEQWQQLLDDRGKIGVAIEELLRYDAPVQYNVRRSNHPVTLHGVT
MMAR_4733|M.marinum_M VFARNPEQWQKLLDDRSKVPAAVEELLRYEAPSQYQVRRAMEDVELHGVT
TH_2539|M.thermoresistible__bu AFADFPDEWQKLRADRSKIPAAIEELLRFEAPSQYQVRVNTRDVTLHGTT
MLBr_02088|M.leprae_Br4923 AMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTT
. : : : : :** **:: . : * :
Mb0789c|M.bovis_AF2122/97 IPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIG-CKLVSFGSGAHFCLG
Rv0766c|M.tuberculosis_H37Rv IPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIG-CKLVSFGSGAHFCLG
MAB_1216c|M.abscessus_ATCC_199 IPAGDILLLLPGSANRDDRVFDDADQYRIGREIG-AKLVSFGSGAHFCLG
MUL_0475|M.ulcerans_Agy99 IPEGDVVLLLPGSAHRDERAFRDPDEYLIGREIG-SKLLSFGSGAHFCLG
MAV_0916|M.avium_104 IPAGKPVFLCGAAANRDPEAFTDADTFDIERDQTEAQHLGLGYGIHSCLG
MSMEG_4818|M.smegmatis_MC2_155 IPAGKPVFLLKASANRDERAWTDPDVFDIDRDRTEAQNLGLGYGIHSCLG
Mflv_2477|M.gilvum_PYR-GCK IPEGKPVFLLAGSANRDPDAFTDADTFDIDRDRSEAQNLGFGYGVHSCLG
Mvan_2001|M.vanbaalenii_PYR-1 IPAGAPVFLLGASANRDPDAWTAPDVFDINRDRTEAQNLGFGYGIHSCLG
MMAR_4733|M.marinum_M IPAGKPVFLINGAANRDPHAWTDPDKFDIDRDPHEATNLGFGYGIHSCLG
TH_2539|M.thermoresistible__bu IPEGSAVLLLTGSALRDERVFRDPDRLDIDRDRVMGFNLAFGYGIHSCLG
MLBr_02088|M.leprae_Br4923 LTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSS--RHLAFAVGSHFCLG
:. * :.* .:* ** .: .* * :.:. * * ***
Mb0789c|M.bovis_AF2122/97 AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
Rv0766c|M.tuberculosis_H37Rv AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
MAB_1216c|M.abscessus_ATCC_199 AHLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLR
MUL_0475|M.ulcerans_Agy99 AHLARMEARVALTELFKRIRGYQVDEGNAVRVHSSNVRGFAHLPITVEVA
MAV_0916|M.avium_104 AALARLESRIALERLLDFMPRYEVDWAGCRRVTMQNVAGWKNVPVKVLR-
MSMEG_4818|M.smegmatis_MC2_155 AALARLESTIALERLLDFMPRYEVKWDGLQRVHMQNVAGYSHVPVKVLR-
Mflv_2477|M.gilvum_PYR-GCK AALARMESAIALDRLLDFMPRYEVLFDECRRVSAQNVAGWSHVPVRVLR-
Mvan_2001|M.vanbaalenii_PYR-1 AALARLESSIALDMLLDFMPRYGVEWDGCRRVSMQNVSGWANVPVRIL--
MMAR_4733|M.marinum_M AALARMESAIALEKLLDFMPAFEVDWAGCKRVHMQNVAGWQSVPVRVLR-
TH_2539|M.thermoresistible__bu AALARMESRIALEALLDLIPEYEVDRAGLRRVQMSNVSGFKNVPVRAGR-
MLBr_02088|M.leprae_Br4923 AALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV---
* ***:*: ::* : : : : * :*:
Mb0789c|M.bovis_AF2122/97 ---
Rv0766c|M.tuberculosis_H37Rv ---
MAB_1216c|M.abscessus_ATCC_199 EGR
MUL_0475|M.ulcerans_Agy99 ---
MAV_0916|M.avium_104 ---
MSMEG_4818|M.smegmatis_MC2_155 ---
Mflv_2477|M.gilvum_PYR-GCK ---
Mvan_2001|M.vanbaalenii_PYR-1 ---
MMAR_4733|M.marinum_M ---
TH_2539|M.thermoresistible__bu ---
MLBr_02088|M.leprae_Br4923 ---