For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3042 | - | - | 100% (284) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_4323 | - | 1e-27 | 35.24% (210) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_1828 | - | 2e-26 | 35.29% (238) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2237c | ephD | 9e-30 | 33.05% (236) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4561 | - | 1e-117 | 73.79% (290) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2214c | ephD | 9e-30 | 33.05% (236) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 1e-27 | 33.86% (251) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1382 | - | 1e-28 | 31.37% (271) | putative oxidoreductase EphD |
| M. marinum M | MMAR_2600 | - | 6e-30 | 37.83% (230) | short-chain dehydrogenase |
| M. avium 104 | MAV_3031 | - | 1e-100 | 67.03% (276) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2876 | - | 1e-120 | 74.74% (289) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. ulcerans Agy99 | MUL_3160 | - | 5e-31 | 38.26% (230) | short-chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2873 | - | 1e-126 | 78.67% (286) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVP
Rv2214c|M.tuberculosis_H37Rv MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVP
MAB_1382|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2600|M.marinum_M --------------------------------------------------
MUL_3160|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 LLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPV
Rv2214c|M.tuberculosis_H37Rv LLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPV
MAB_1382|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2600|M.marinum_M --------------------------------------------------
MUL_3160|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 HVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGGLRRP
Rv2214c|M.tuberculosis_H37Rv HVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGGLRRP
MAB_1382|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2600|M.marinum_M --------------------------------------------------
MUL_3160|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 WRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGDIP
Rv2214c|M.tuberculosis_H37Rv WRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGDIP
MAB_1382|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2600|M.marinum_M --------------------------------------------------
MUL_3160|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 VDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVN
Rv2214c|M.tuberculosis_H37Rv VDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVN
MAB_1382|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2600|M.marinum_M --------------------------------------------------
MUL_3160|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu --------------------------------------------------
Mvan_2873|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2876|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4561|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3031|M.avium_104 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 SQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL
Rv2214c|M.tuberculosis_H37Rv SQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL
MAB_1382|M.abscessus_ATCC_1997 -------------------------------------------------M
MMAR_2600|M.marinum_M ----------------------------------------------MFKL
MUL_3160|M.ulcerans_Agy99 ----------------------------------------------MFKL
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
TH_3042|M.thermoresistible__bu ---------------VDAHEVFGGGVAVITGAGHGVGAGLARYAASLGMT
Mvan_2873|M.vanbaalenii_PYR-1 --------------MSDAREIFGGGVAVITGAGNGIGAGLARHAAALGMT
MSMEG_2876|M.smegmatis_MC2_155 --------------MSQARETFGGGVAVITGAGAGIGAGLARYAHRLGMT
Mflv_4561|M.gilvum_PYR-GCK ---------------MSARGTFAGGVAVITGAGAGIGAGLARYASSLGMT
MAV_3031|M.avium_104 ---------------------------MITGAGSGLGAGLARYACGLGMT
Mb2237c|M.bovis_AF2122/97 ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAE
Rv2214c|M.tuberculosis_H37Rv ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAE
MAB_1382|M.abscessus_ATCC_1997 AQGED--------QVKRS----DIKLVVVTGAGSGIGRAAAERFAQLGAR
MMAR_2600|M.marinum_M NSGTN--------TSDLAG-----RVVAITGAGSGIGRELALLCAQRGAD
MUL_3160|M.ulcerans_Agy99 NSGTN--------TSDLAG-----RVVAITGAGSGIGRELALLCAQRGAD
MLBr_01094|M.leprae_Br4923 -------------MEGFAG-----KVAVVTGAGSGIGQALAIELARSGAK
:**** *:* * *
TH_3042|M.thermoresistible__bu VVLADVDAAAIAALRGELPGS----VGQVCDVRDPDALEMLAARVYSEVG
Mvan_2873|M.vanbaalenii_PYR-1 VVLADIDEQAIGALSDELPGS----FASGCDVRDPEALEMLAAQVYSDIG
MSMEG_2876|M.smegmatis_MC2_155 VVLADVDEAAAAALRDELRADGGTAVAEKCDVRDPDAVADLADRTYRDLG
Mflv_4561|M.gilvum_PYR-GCK VVLVDIDAGAVAGLRAELEAAGGVAVDAMCDVRDPVAVQELADRVYRDVG
MAV_3031|M.avium_104 VVLADIDRDAVAALRDELAAGGGAAHDAACDVRDPAAVQDLADRAY-DIG
Mb2237c|M.bovis_AF2122/97 IVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHG
Rv2214c|M.tuberculosis_H37Rv IVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHG
MAB_1382|M.abscessus_ATCC_1997 VIVSDINEVAAEATVAAIRDAGGDSCARRLDVTDVNEFEDFARWVQSEHG
MMAR_2600|M.marinum_M LALCDINDTAVADTAQTARGFGHDVITRRVDVSDPEQMTAFADATLGHFG
MUL_3160|M.ulcerans_Agy99 LALCDINDTAVADTAQTARGFGHDVITRRVDVSDPEQMTAFADATLGHFG
MLBr_01094|M.leprae_Br4923 LAISDVDGEGLAQTEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFG
: : *:: ** : . * . . *
TH_3042|M.thermoresistible__bu PVRLLVNNAGIEQFGYLWDTPVPNWDRLVSVNVSGVFYGIRAFLPRMIDA
Mvan_2873|M.vanbaalenii_PYR-1 PVRLLINNAGVEQFGYLWDTPVANWNRVMDINVSGVFHGVKAFLPRMIAA
MSMEG_2876|M.smegmatis_MC2_155 PVRLLVNNAGVEQFGYLWDTPVANWNRVMDINVSGVFHGVRAFLPKMMAH
Mflv_4561|M.gilvum_PYR-GCK PVRLLVNNAGVEQFGYLWDTPVANWNRIMDINVDGVFHGVRAFLPKMIDA
MAV_3031|M.avium_104 PVRLLVNNAGIEQFGYLWDTPVVNWQRVMDVNVSGVFYGVRAFLPKMMAA
Mb2237c|M.bovis_AF2122/97 VPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVER
Rv2214c|M.tuberculosis_H37Rv VPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVER
MAB_1382|M.abscessus_ATCC_1997 VCDVVVNNAGIGILGEVIDTTESDWDRIVGINLLGMVHGARLFAQQMVDA
MMAR_2600|M.marinum_M GVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEAFLPAMIES
MUL_3160|M.ulcerans_Agy99 GVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEAFLPAMIES
MLBr_01094|M.leprae_Br4923 KVNQIYNNAGIAFTGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISS
: ****: * . : : : :: :: *:. * . * ::
TH_3042|M.thermoresistible__bu GAPAWVWNLSSIGGVAAVPLQAPYIMSKHAVLALTECLRLEVELAGHADR
Mvan_2873|M.vanbaalenii_PYR-1 GAPAWVWNLSSIGGVAAVPLQAPYIVSKHAVLALTECLRLEVELAGHGHF
MSMEG_2876|M.smegmatis_MC2_155 GSPAWVWNLSSIGGVAAVPLQAPYIISKHAVLALTECLRLEVQLAGHDDH
Mflv_4561|M.gilvum_PYR-GCK GTPAWVWNMSSIGGVAVVPLQAPYIVTKHAVLALTECLHLEVRHAGH-DH
MAV_3031|M.avium_104 GQQAWVWNIASVGAVVAMPLQAPYIVSKHAVLSLTECLHLEVQATGHDDH
Mb2237c|M.bovis_AF2122/97 GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAG----
Rv2214c|M.tuberculosis_H37Rv GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAG----
MAB_1382|M.abscessus_ATCC_1997 NKPGHIVNVASAAAFLPMPNLASYSATKYAVKMFTDCIRGELAPNH----
MMAR_2600|M.marinum_M GRGGHVVNLSSAAGLLANSALSAYSATKFAVLGLSEALRIELEPHR----
MUL_3160|M.ulcerans_Agy99 GRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEALRIELEPHR----
MLBr_01094|M.leprae_Br4923 GD-GHVINISSVFGLFSVPGQAAYNSAKFAVRGFTEALREEMALAGR--P
. . : *::* . :.* :* *. :::.:: *:
TH_3042|M.thermoresistible__bu ITVQAVLPGAVKSNIFEAAGGVDD----GDVAAAEAQRAAMLDIKAAA--
Mvan_2873|M.vanbaalenii_PYR-1 IHVQAVLPGAVKSNIFEAAGGVDASAAGTDVAAAEAQREAMLDIKAAA--
MSMEG_2876|M.smegmatis_MC2_155 VHVQAVLPGAVKSNIFEAAGGVDSGQDGADVNAAESQREAMLDIKAAA--
Mflv_4561|M.gilvum_PYR-GCK IHVQAVLPGAVVSNIFESARGVDDS-DSEAVTAAESQRAAMLDIKAAA--
MAV_3031|M.avium_104 VHVQAVLPGPVRSNIFESAGGVDPD-AATDAAAAEAHRSAMLGIKAAS--
Mb2237c|M.bovis_AF2122/97 VGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSY---
Rv2214c|M.tuberculosis_H37Rv VGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSY---
MAB_1382|M.abscessus_ATCC_1997 IGASVICPGPIMTNIFSS-ATHTGADEQEQVQRSALTGAAFEKIRSWHLI
MMAR_2600|M.marinum_M IGVTAICPGVINTAITKASPIRGAGDTE----GRRQRLTVTYQRRGY---
MUL_3160|M.ulcerans_Agy99 IGVTAICPGVINTAITKASPIRGAGDTE----GRRQRLTVTYQRRGY---
MLBr_01094|M.leprae_Br4923 VNVTTVYPGGIKTAIARNATAAEGLDVS----------KIASRFDTWVAH
: .: ** : : *
TH_3042|M.thermoresistible__bu MDPVEAARVVFEQAAAGEFYLLTQPEYVGGAMAERAAVLTERRAPVLRTE
Mvan_2873|M.vanbaalenii_PYR-1 MDPVEAAEVVFEQSAQDVFYLLTQPDYVGSAMAERAGVLTSQVPPQLRTQ
MSMEG_2876|M.smegmatis_MC2_155 MDPIDAAEAIFEQSARGAFYLLTQPEYVGSAMAERAQVLISQVPPQLRTE
Mflv_4561|M.gilvum_PYR-GCK MDPVAAAEVVFDQAAAGEFYLLTQPGYVSSAMTERARVLSTRQAPQLRTE
MAV_3031|M.avium_104 MDALEAAEMIFRQSTEGHFYLHTHPESVGAAMRERAKVLAAQQAPRLRTE
Mb2237c|M.bovis_AF2122/97 -GPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL---
Rv2214c|M.tuberculosis_H37Rv -GPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL---
MAB_1382|M.abscessus_ATCC_1997 PGPQNVARAIESAVVYNRKTVLVRPEAYLVYLLRRLSPTLLYAFSNLIFG
MMAR_2600|M.marinum_M -TPARAARNILRAVERNKAVAPVAAEAHVMYVLSRIMPPLARWVSAQMAK
MUL_3160|M.ulcerans_Agy99 -TPARAARNILRAVERNKAVAPVAAEAHVMYVLSRIMPPLARWVSAQMAK
MLBr_01094|M.leprae_Br4923 TSPQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVA
. .* : . . *
TH_3042|M.thermoresistible__bu QRFDPARH--------------
Mvan_2873|M.vanbaalenii_PYR-1 RRFEPDRH--------------
MSMEG_2876|M.smegmatis_MC2_155 RRFDPAKH--------------
Mflv_4561|M.gilvum_PYR-GCK RRFDPAKH--------------
MAV_3031|M.avium_104 TRFDSAPD--------------
Mb2237c|M.bovis_AF2122/97 -RVI------------------
Rv2214c|M.tuberculosis_H37Rv -RVI------------------
MAB_1382|M.abscessus_ATCC_1997 SRTITFAYRLGKNPTVARLLGR
MMAR_2600|M.marinum_M AAK-------------------
MUL_3160|M.ulcerans_Agy99 AAK-------------------
MLBr_01094|M.leprae_Br4923 SRLILNQR--------------