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M. thermoresistible (build 8) TH_1828 ()

annotation: PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
coordinates: 3576932 - 3577756
length: 275

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1828 - 100% (275) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_2758 - 2e-37 35.42% (271) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_4323 - 4e-33 35.39% (243) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1277c - 1e-127 82.12% (274) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCK Mflv_2216 - 1e-123 79.85% (273) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1245c - 1e-127 82.12% (274) short-chain type dehydrogenase/reductase
M. leprae Br4923 MLBr_01094 - 1e-114 75.28% (271) short chain alcohol dehydrogenase
M. abscessus ATCC 19977 MAB_1388c - 1e-109 70.44% (274) short-chain dehydrogenase/reductase
M. marinum M MMAR_4195 - 1e-119 79.12% (273) short-chain type dehydrogenase/reductase
M. avium 104 MAV_1384 - 1e-125 81.68% (273) short chain alcohol dehydrogenase
M. smegmatis MC2 155 MSMEG_5053 - 1e-130 83.58% (274) short chain alcohol dehydrogenase
M. ulcerans Agy99 MUL_4501 - 1e-119 78.75% (273) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1 Mvan_4479 - 1e-127 80.95% (273) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2216|M.gilvum_PYR-GCK          MQGFAGKVAVVTGAGSGIGQALAIELGRSGALVAISDVDTEGLAVTEERL
Mvan_4479|M.vanbaalenii_PYR-1       MEGFAGKVAVVTGAGSGIGQALAIELGRSGARVAISDVDTEGLAVTEERL
TH_1828|M.thermoresistible__bu      MQGFAGKVAVITGAGSGIGQALALELGRSGAKVAISDVNTEGLTETEDRL
MSMEG_5053|M.smegmatis_MC2_155      MEGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAICDVDTEGLAATEERL
Mb1277c|M.bovis_AF2122/97           MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
Rv1245c|M.tuberculosis_H37Rv        MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
MLBr_01094|M.leprae_Br4923          MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
MMAR_4195|M.marinum_M               MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MUL_4501|M.ulcerans_Agy99           MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MAV_1384|M.avium_104                MQGFAGKVAVVTGAGSGIGQALAVELARSGAKVAISDVDLEGLAHTEEQL
MAB_1388c|M.abscessus_ATCC_199      MEGFSGKVAVVTGAGSGIGRALAVELARSGAKIAISDIDNEGLAETERQV
                                    *:**:*****:********:***:**.**** :**.*:: :**: **  :

Mflv_2216|M.gilvum_PYR-GCK          KAIGTHVKSDRLNVTERERFLQYADDVAEHFGKVHQIYNNAGIAFTGDIE
Mvan_4479|M.vanbaalenii_PYR-1       KAIGAQVKSDRLDVTERETFLLYADDVAEHFGSVNQIYNNAGIAFTGDIE
TH_1828|M.thermoresistible__bu      KAIGAPVKADRLDVTERAAFEAYADAVVEHFGVVNQIYNNAGIAYTGDIE
MSMEG_5053|M.smegmatis_MC2_155      KAIGAPVKADRLDVTEREAFLLYADAVKEHYGTVNQIYNNAGIAFTGDVE
Mb1277c|M.bovis_AF2122/97           KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
Rv1245c|M.tuberculosis_H37Rv        KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
MLBr_01094|M.leprae_Br4923          KAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVE
MMAR_4195|M.marinum_M               TALGAEVKTDRLDVTEREAFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MUL_4501|M.ulcerans_Agy99           TALGAEVKTDRLDVTERETFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MAV_1384|M.avium_104                KAIGAQYKADRLDVTEREAFLAYADAVKEHFGKVNQIYNNAGIAFTGDVE
MAB_1388c|M.abscessus_ATCC_199      KALGAEVRADRLNVAEREAFLLYADAIKDHFGKVNQIYNNAGIAYQGEVE
                                    .*:.:  ::***:*:**  *  *** : :::* *:********.. *::*

Mflv_2216|M.gilvum_PYR-GCK          VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
Mvan_4479|M.vanbaalenii_PYR-1       ITQFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
TH_1828|M.thermoresistible__bu      VSHFKDIERVMDVDFWGVVNGTKVFLPHLIASGDGHVINISSVFGLFSVP
MSMEG_5053|M.smegmatis_MC2_155      ISEFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVINVSSVFGLFSVP
Mb1277c|M.bovis_AF2122/97           VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSAP
Rv1245c|M.tuberculosis_H37Rv        VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSAP
MLBr_01094|M.leprae_Br4923          VSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSVP
MMAR_4195|M.marinum_M               VCAFKDIDRVMDVDFGGVLNGTKAFLPYLIASGDGHVINVSSVFGLFSVS
MUL_4501|M.ulcerans_Agy99           VCAFKDIDRVMDVDFGGVLNGTKTFLPYLIASGDGHVINVSSVFGLFSVS
MAV_1384|M.avium_104                VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
MAB_1388c|M.abscessus_ATCC_199      ESQFKDIERIIDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSLFGVLSMP
                                       ****:*::***: **:****.***:**:******:*:**:**::* .

Mflv_2216|M.gilvum_PYR-GCK          GQGAYNAAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNAGA
Mvan_4479|M.vanbaalenii_PYR-1       GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNASA
TH_1828|M.thermoresistible__bu      GQAAYNAAKFAVRGFTEALRQEMILAGHPVKVTTVHPGGIKTGIARNMTA
MSMEG_5053|M.smegmatis_MC2_155      GQAAYNSAKFAVRGFTEALRQEMAIAKHPVKVTTVHPGGIKTAIARNATA
Mb1277c|M.bovis_AF2122/97           GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNATA
Rv1245c|M.tuberculosis_H37Rv        GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNATA
MLBr_01094|M.leprae_Br4923          GQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNATA
MMAR_4195|M.marinum_M               GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MUL_4501|M.ulcerans_Agy99           GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MAV_1384|M.avium_104                GQAAYNSAKFAVRGFTEALRQEMAAAGHPVAVTTVHPGGIKTAIARNATA
MAB_1388c|M.abscessus_ATCC_199      GQSAYNSAKFAVRGFTESLRQEMIIGKKPVAVTCVHPGGIKTAIARNSTT
                                    **.***:**********:**:**  . :** *: *:***:**.****  :

Mflv_2216|M.gilvum_PYR-GCK          AEGLDAEELAKTFDKKLASTTPEKAAQVILDGVRKNKARILIGNDAKMFE
Mvan_4479|M.vanbaalenii_PYR-1       AEGLDAEELAKAFDKKLASTTPEKAAKIILDGVRKNRARILVGNDAKVFD
TH_1828|M.thermoresistible__bu      AEGLDAQELARAFDTKLARTSPEKAAQIILDGVRKNKARVLVGTDAKILD
MSMEG_5053|M.smegmatis_MC2_155      AEGLDAKELAEAFDKKLANTTPQRAAVIILDGVRKNKARVLVGPDAKILD
Mb1277c|M.bovis_AF2122/97           AEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLD
Rv1245c|M.tuberculosis_H37Rv        AEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLD
MLBr_01094|M.leprae_Br4923          AEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVAN
MMAR_4195|M.marinum_M               AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MUL_4501|M.ulcerans_Agy99           AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MAV_1384|M.avium_104                AEGLDQAELAKLFDKRLAKTTPQRAAQIILDAVRKKKARVLVGSDAKALD
MAB_1388c|M.abscessus_ATCC_199      AEGYDQQAMAAMFDKYLANTSPEAAARIILTAVRKKKPRVLVGPDAKILD
                                    *** *   :*  **. :*  :*: ** :** .* *::.*:*:* ***  :

Mflv_2216|M.gilvum_PYR-GCK          IAIRALG-AGYQSVFPKVVARLTPPAK--
Mvan_4479|M.vanbaalenii_PYR-1       VVVRVLG-AGYQSLFPKAVARLTPPAK--
TH_1828|M.thermoresistible__bu      AIVRLTG-SGYQRLFPKFVARTMPR----
MSMEG_5053|M.smegmatis_MC2_155      VIVRITG-SGYQRLFSAVAAKAMPR----
Mb1277c|M.bovis_AF2122/97           LVVRLTG-SGYQRIFPIITGRLIPRPR--
Rv1245c|M.tuberculosis_H37Rv        LVVRLTG-SGYQRIFPIITGRLIPRPR--
MLBr_01094|M.leprae_Br4923          VVVRFSGGAGYQRLFAQVASRLILNQR--
MMAR_4195|M.marinum_M               IVVRLTG-SGYQRLFMPVLGRLVPASHR-
MUL_4501|M.ulcerans_Agy99           IVVRLTG-SGYQRLFMPVLGRLVPASHR-
MAV_1384|M.avium_104                ILVRLTG-SGYQRLFGPVMSRLLPN----
MAB_1388c|M.abscessus_ATCC_199      VIVRLTG-ARYQDIFSVVTRFILPRPGKK
                                      :*  * : ** :*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1828		-	100% (275)	PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_2758	-	2e-37	35.42% (271)	PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_4323	-	4e-33	35.39% (243)	PUTATIVE short-chain dehydrogenase/reductase SDR