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M. thermoresistible (build 8) TH_2799 (-)

annotation: acyl-CoA dehydrogenase
coordinates: 3367253 - 3368431
length: 393

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2799--100% (393)acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_4197-8e-7337.23% (411) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4263-3e-6037.78% (397) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1969cfadE173e-6538.26% (413) acyl-CoA dehydrogenase FADE17
M. gilvum PYR-GCKMflv_2334-1e-11352.78% (396) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1934cfadE174e-6538.26% (413) acyl-CoA dehydrogenase FADE17
M. leprae Br4923MLBr_00737fadE255e-1825.67% (335) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-2e-6439.20% (398) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_2862fadE171e-6037.34% (399) acyl-CoA dehydrogenase FadE17
M. avium 104MAV_1878-1e-6137.40% (361) acyl-CoA dehydrogenase family protein
M. smegmatis MC2 155MSMEG_1904-1e-12055.05% (396) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2892fadE172e-5937.94% (369) acyl-CoA dehydrogenase FadE17
M. vanbaalenii PYR-1Mvan_4313-1e-11452.30% (392) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1904|M.smegmatis_MC2_155      ---MTN-ELPTPEELAAE--------VREWLAQNWK-------GLPKQTD
Mvan_4313|M.vanbaalenii_PYR-1       ---MTTPSLPSADELGAE--------VRDWLRDNWT-------PLPKNTD
Mflv_2334|M.gilvum_PYR-GCK          ---MSDNNLPSAEDLRTE--------VREWLAENWTG-----VTLPKSDD
TH_2799|M.thermoresistible__bu      ---MSE---LTDDQVRTE--------VREWLAANWK--------------
Mb1969c|M.bovis_AF2122/97           ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
Rv1934c|M.tuberculosis_H37Rv        ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
MMAR_2862|M.marinum_M               ---MDVAYPPEAEEFRER--------VRAFLDEHLPCGWSGPGAL--AVQ
MUL_2892|M.ulcerans_Agy99           ------------------------------MDEHLPCGWSGPGAL--AVQ
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MAV_1878|M.avium_104                ---MEYGMRPELAEFRAE--------VRAFVAEHAPAIPPRAGVR--SAE
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLP------EEHNELRATIRALAEKEIAPHAADVD
                                                                                      

MSMEG_1904|M.smegmatis_MC2_155      PWVSTPERIAWLEKVVDAGYAVPSYPKQWWGRE-YPHKLASVIEKEFRAV
Mvan_4313|M.vanbaalenii_PYR-1       PWASSPERIAWLEKVLDAGYAVPTYPAEWFGRG-YPNKLANVIGQEFAAI
Mflv_2334|M.gilvum_PYR-GCK          PWVSSPERIAWLEKVVAAGYGAPTYPTEWYGRA-YPNKLAKVIAEEFRAV
TH_2799|M.thermoresistible__bu      ---PGMDRAEWARLVFEAGWAVPSWEPQWYGRG-LTDPQSRIVAAEFAAV
Mb1969c|M.bovis_AF2122/97           EREEFARH--WRRALAGAGLVAVSWPTEYGGGG-LSPMEQVVLAEEFARA
Rv1934c|M.tuberculosis_H37Rv        EREEFARH--WRRALAGAGLVAVSWPTEYGGGG-LSPMEQVVLAEEFARA
MMAR_2862|M.marinum_M               DRKAFAAR--WRQLLVAAGLIAVSWPKEYGGGG-YSPVEQVVLAEEFARA
MUL_2892|M.ulcerans_Agy99           DRKAFAAR--WRQLLVAAGLIAVSWPKEYGGGG-YSPVEQVVLAEEFARA
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRG-ATVSQRVIFYEEYARA
MAV_1878|M.avium_104                NDAEFKALQEWTGRLFEAGYVGADWPVEFGGRGDFTPEHSIIVGEELARA
MLBr_00737|M.leprae_Br4923          QRARFPEEA--LAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARV
                                                  :  :*        :  *          :.  *    

MSMEG_1904|M.smegmatis_MC2_155      RAPGSRLD---KYSIPANTILMFGNDTIKQHLLYEFLTERSRTCLLYSEP
Mvan_4313|M.vanbaalenii_PYR-1       KAPGSRQD---KYNIPANTVLALGTGKLREDLLRDFLVERARTCLLYSEP
Mflv_2334|M.gilvum_PYR-GCK          GAPGACQD---RFSIPANTSLAFGTEQLKADLLHEFLTENSRTCLLYSEP
TH_2799|M.thermoresistible__bu      GAPGTGHD---RANLFACTLHDLGTEEQKRRLIPPSIRGETRWCLLYSEP
Mb1969c|M.bovis_AF2122/97           GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
Rv1934c|M.tuberculosis_H37Rv        GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
MMAR_2862|M.marinum_M               GAPEREENDLFGVDLLGNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEP
MUL_2892|M.ulcerans_Agy99           GAPEREENDLFGVDLLCNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEP
MAB_0597|M.abscessus_ATCC_1997      EAPHKVNH--LGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEP
MAV_1878|M.avium_104                QAPSAQSG----SVLASHALIHYGTDEQRRRHLPEIRGGRELWCQLFSEP
MLBr_00737|M.leprae_Br4923          DASASLIP--AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
                                     *.           :        *.   :   :          .   ** 

MSMEG_1904|M.smegmatis_MC2_155      GAGSDLAAVRTTAVRDGDEWMVNGQKVWTSGAATSEYALLIARTDWDVPK
Mvan_4313|M.vanbaalenii_PYR-1       GAGSDLASVRTTAVRQGDHWVVNGQKVWTSGAQTADYALLLARTDWDVPK
Mflv_2334|M.gilvum_PYR-GCK          GAGSDLAGVRTTAVRDGDQWIINGQKVWTSGAQTSQYALLIARTDWDVPK
TH_2799|M.thermoresistible__bu      GAGSDLAGLRTRAERDGDEWVINGQKVWTSFAQTADYGLLVARTDWDVPK
Mb1969c|M.bovis_AF2122/97           EAGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAK
Rv1934c|M.tuberculosis_H37Rv        EAGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAK
MMAR_2862|M.marinum_M               EAGSDLASVRTRAVLDGDQWVINGQKIWTSAGSTANWIFVLARTDPVAPK
MUL_2892|M.ulcerans_Agy99           EAGSDLASVRTRAVLDGDQWVINGQKIWTSAGSTANWIFVLARTDPVAPK
MAB_0597|M.abscessus_ATCC_1997      GAGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVVARTEPGSSR
MAV_1878|M.avium_104                GAGSDLASLRTRAVRHGDTYTIDGQKVWTTDGHWARYGYLLARTDPDAPK
MLBr_00737|M.leprae_Br4923          EAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD-KG
                                     **** * : * .  .*. : ::* * * : .  : :  ::* *:     

MSMEG_1904|M.smegmatis_MC2_155      HKGLSFFVIPMKQPGIEVRPLVQITGE--SHFNEVFITDARVSDEYLVGG
Mvan_4313|M.vanbaalenii_PYR-1       HKGLSLFIMPMNQAGIEVRPLVQITGE--SHFNEVFISDATVSDDYLLGG
Mflv_2334|M.gilvum_PYR-GCK          HKGITFFIVPMKQPGIEIRPLVQITGD--SHFNEVFITDATVPDAYVVGG
TH_2799|M.thermoresistible__bu      HKGISFFMLPMKQPGIEVRPIHQITGE--SEFNEVFITDARCPAENMVGR
Mb1969c|M.bovis_AF2122/97           HRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAGNVVGR
Rv1934c|M.tuberculosis_H37Rv        HRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAGNVVGR
MMAR_2862|M.marinum_M               HQGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADARTGVANVVGE
MUL_2892|M.ulcerans_Agy99           HQGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADARTGVANVVGE
MAB_0597|M.abscessus_ATCC_1997      HKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTSADLVVGE
MAV_1878|M.avium_104                HKGISAFILDMSAPGVSVRPLRELTGT--SDFNEVFFDGVEVPADAMIGA
MLBr_00737|M.leprae_Br4923          ANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE
                                     .*:: :::  .  .. : *  :  *   *  .*:::         ::* 

MSMEG_1904|M.smegmatis_MC2_155      EGNGWRVLQTALAYERSIMGDSGRGSRNKS--------KADSLVELAR--
Mvan_4313|M.vanbaalenii_PYR-1       EGNGWRALQTALAYERSIMGDSGRGSRNR---------KADSLIDLAR--
Mflv_2334|M.gilvum_PYR-GCK          VGNGWRVLQTALAVERSIMGSGTSLHRKQS--------RGNSLVEMAR--
TH_2799|M.thermoresistible__bu      PGEGWSVLQVALGYERRLMGDLARTSKASRKPKDDPAQQRNALVEMAR--
Mb1969c|M.bovis_AF2122/97           VGDGWSTAMTLLGFERGSHIATAAIDFER---------DLQRLCELAR--
Rv1934c|M.tuberculosis_H37Rv        VGDGWSTAMTLLGFERGSHIATAAIDFER---------DLQRLCELAR--
MMAR_2862|M.marinum_M               VGSGWTAAMSLLGFERGAQATTGAIDFAR---------DLSRLCDLAR--
MUL_2892|M.ulcerans_Agy99           VGSGWTAAMSLLGFERGAQATTGAIDFAR---------DLSRLCDLAR--
MAB_0597|M.abscessus_ATCC_1997      PGDGWRVAMGTLTFERGVSTLGNQITYAR---------ELSRLAELAK--
MAV_1878|M.avium_104                PGQGWAIANATLAHERTNVG--GIVVKLR--------LAIDALIDLARRV
MLBr_00737|M.leprae_Br4923          PGTGFKTALATLDHTRPTIGAQAVGIAQG---------ALDAAIVYTKDR
                                     * *:      *   *                        .     ::  

MSMEG_1904|M.smegmatis_MC2_155      --EHG-RLDDPAIRKELANVLALRELNRLNNARAKASAGQG--TSTSIMS
Mvan_4313|M.vanbaalenii_PYR-1       --EHG-VLDDSAVRHQLASVLAMRELNRLNNARAKASTTQG--TSSSIMS
Mflv_2334|M.gilvum_PYR-GCK          --AHG-KLDDSAIRKSLADVLALRELNNLNNARAKAEAKQG--TASPVMS
TH_2799|M.thermoresistible__bu      --EAG-RLDDPYIRQRIARMDEFAAVNRWNTQRSKATRDKV--ESLTLQA
Mb1969c|M.bovis_AF2122/97           --DRG-LHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGR-PPGAEAA
Rv1934c|M.tuberculosis_H37Rv        --DRG-LHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGR-PPGAEAA
MMAR_2862|M.marinum_M               --ARG-LDSDPRIRDRLAWCYSRTQIMRYRGYRSLTWALNGL-LPGAEAA
MUL_2892|M.ulcerans_Agy99           --ARG-LDSDPRIRDRLAWCYSRTQIMRYRGYCSLTWALNGV-LPGAEAA
MAB_0597|M.abscessus_ATCC_1997      --SNG-AADDPAIRERLAQAYVGMRTMRAYALATMDEERPG------QDN
MAV_1878|M.avium_104                TIDGGPAIDSDRVRDRIGQFSAEVEALSALTYANLTRWLRGR-ERMHDAA
MLBr_00737|M.leprae_Br4923          KQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISA
                                                ::  :.                                

MSMEG_1904|M.smegmatis_MC2_155      LGKLAMSHILHSEARLKTEIIGAEALLAG----------PENPEADD---
Mvan_4313|M.vanbaalenii_PYR-1       LGKLAMSRILHTEAAMKTQIIGAEALLAG----------PDNPVADD---
Mflv_2334|M.gilvum_PYR-GCK          LGKLATSGILHAEARLKTDIIGADALLAG----------PDNAEADE---
TH_2799|M.thermoresistible__bu      LGKIAMSRILHETARVQTEIVGAESMLAG----------PDHPIGDG---
Mb1969c|M.bovis_AF2122/97           ITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPAC
Rv1934c|M.tuberculosis_H37Rv        ITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPAC
MMAR_2862|M.marinum_M               ISKVIWSEYFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPAC
MUL_2892|M.ulcerans_Agy99           ISKVIWSEYFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPAC
MAB_0597|M.abscessus_ATCC_1997      VSKLLWANWHRDLGELAMEIIGTSTLLTN------------AGEMDE---
MAV_1878|M.avium_104                MGKLMFSEINLEMAAFAVELAGEAGVLVE----------GDDNVLDG-GR
MLBr_00737|M.leprae_Br4923          ASKCFASDIAMEVTTDAVQLFGGAGYTSDFP-------------------
                                      *   :           :: *                            

MSMEG_1904|M.smegmatis_MC2_155      INFLTLNAFFTSIGGGTDQVQRNIIGERVLGLPKEPEVDRDIPFREARRS
Mvan_4313|M.vanbaalenii_PYR-1       VNFLALNAFFTSIGGGTDQIQRNIIGERVLGLPKEPEADRDIPFRQARRS
Mflv_2334|M.gilvum_PYR-GCK          VNFLTLNAFFTSIGGGTDQIQRNIIGERVLGLPKEPEVDREIPFRDIRKN
TH_2799|M.thermoresistible__bu      VTFRTLNAYFTSIGGGTDQVQRNIVGERVLGLPKEPDPYRDQPFRDLPH-
Mb1969c|M.bovis_AF2122/97           WMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEP---RPEVLC-----
Rv1934c|M.tuberculosis_H37Rv        WMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEP---RPEVLC-----
MMAR_2862|M.marinum_M               WMDELLYARAATIYAGSSQIQRNVIGEQLLGLPKEP---RREAVH-----
MUL_2892|M.ulcerans_Agy99           WMDELLYARAATIYAGSSQIQRNVIGEQLLGLPKEP---RREAVH-----
MAB_0597|M.abscessus_ATCC_1997      WQRLFLFSRADTIYGGSNEIQRNIISERVLGLPREA---R----------
MAV_1878|M.avium_104                WQDEWLYARAYTIAGGSSEIMRNLIAERGLGLPRD---------------
MLBr_00737|M.leprae_Br4923          VERFMRDAKITQIYEGTNQIQRVVMSRALLR-------------------
                                           :    *  *:.:: * ::..  *