For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4197 | - | - | 100% (417) | putative acyl-CoA dehydrogenase domain protein |
| M. thermoresistible (build 8) | TH_0805 | - | 5e-87 | 48.30% (352) | acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2799 | - | 8e-73 | 37.23% (411) | PUTATIVE acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1969c | fadE17 | 2e-63 | 36.75% (400) | acyl-CoA dehydrogenase FADE17 |
| M. gilvum PYR-GCK | Mflv_0344 | - | 1e-81 | 45.89% (353) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1934c | fadE17 | 2e-63 | 36.75% (400) | acyl-CoA dehydrogenase FADE17 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-17 | 29.74% (195) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3122 | - | 8e-80 | 46.00% (350) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1953 | fadE34_1 | 2e-71 | 43.54% (356) | acyl-CoA dehydrogenase FadE34_1 |
| M. avium 104 | MAV_0587 | - | 2e-62 | 38.98% (372) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6584 | - | 4e-85 | 47.16% (352) | acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_4144 | fadE34 | 7e-64 | 40.62% (352) | acyl-CoA dehydrogenase FadE34 |
| M. vanbaalenii PYR-1 | Mvan_0394 | - | 3e-86 | 47.63% (359) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 MVATVTDEQFAARALVRDWARNASTGPGGTAAIRDVEQGNPDAWRPVFAR
MUL_4144|M.ulcerans_Agy99 MVAIVSDQQLAARELVRDWARTAAAGEIPTAASREIERGNADAWRPVFTG
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 LAELGIFGVAVPEEAGGAGGSVEDLCAMVEEAAKALIPGPVATTALATLV
MUL_4144|M.ulcerans_Agy99 LAELGLFGVAVPEDHGGAGGIIEDLCAMIEEAAKALVPGPVASTAVATAV
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 LSDA----ELLAALAAGERFAGLALQGDITFDGAASTASGTLPFVLGAAD
MUL_4144|M.ulcerans_Agy99 LAEAGAEPQLLAALASGDRFAGLALEGELQFDQNTSLASGSAPLVLGAIA
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 GGVLLLPADGRWLVVDTASDGVHIEPLAATDFSRPLARVVLDSAPATVLA
MUL_4144|M.ulcerans_Agy99 GGVVLLPAGASWLLVDTTAEGVAVEPLAATDFSRPLARVVLAAAPALSLG
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 ---------------------------------------MPVTSSEPSSA
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 QTPERVEELAATVLAAEAAGITRWSLQTAVDYAKVREQFGKPIGSFQAIK
MUL_4144|M.ulcerans_Agy99 ELGQRVEDLTATVLAAEAAGVTRWALETAVAYAKVREQFGKPIGSFQAIK
MLBr_00737|M.leprae_Br4923 --------------------------------------------MVGWSG
Mb1969c|M.bovis_AF2122/97 ----MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHEREE-----
Rv1934c|M.tuberculosis_H37Rv ----MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHEREE-----
Mflv_0344|M.gilvum_PYR-GCK ------MG--TDADLVADTARRVVAEHDPKTV------------------
Mvan_0394|M.vanbaalenii_PYR-1 ------MG--TDADRVADAARRVVDEHDPKTV------------------
MSMEG_6584|M.smegmatis_MC2_155 ------MSSVAEADLVAERARQVVSEHDPKSV------------------
MAB_3122|M.abscessus_ATCC_1997 GSNALHTSGSSQRDRVAAAAHEVLAKHPPATT------------------
MMAR_1953|M.marinum_M ---------MTAADDLQSRVQTLLDAHPPATS------------------
TH_4197|M.thermoresistible__bu MNARLPITAATPVDDAVAAVEDWVAAHVPEHWRAAAAEGPAALRAVRSP-
MAV_0587|M.avium_104 HLCAEMLCRAEQAEVAAADAARAAAEDDPAQFSLAAALAAATAITAVKAN
MUL_4144|M.ulcerans_Agy99 HLCAEMLCRAEQADVAAADAARAAAESDDQQFALAAALAASIGISAAKAN
MLBr_00737|M.leprae_Br4923 NPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRAR----------
:
Mb1969c|M.bovis_AF2122/97 --------------------------------------------------
Rv1934c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0344|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0394|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6584|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3122|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1953|M.marinum_M --------------------------------------------------
TH_4197|M.thermoresistible__bu --------------------------------------------------
MAV_0587|M.avium_104 VKDCIQVLGGIGCTWEHDAHLYLRRAHAIGRFLGGAERWLRRITALTQAG
MUL_4144|M.ulcerans_Agy99 VKDCIQVLGGIGCTWEHDAHLYLRRAHSIGRFLGGAERWLRRVAALTQAG
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb1969c|M.bovis_AF2122/97 -----------------------------FARHWRRALAGAGLVAVSWPT
Rv1934c|M.tuberculosis_H37Rv -----------------------------FARHWRRALAGAGLVAVSWPT
Mflv_0344|M.gilvum_PYR-GCK -----------------------------PIQQFLGACFDAGLSWVHFPE
Mvan_0394|M.vanbaalenii_PYR-1 -----------------------------PIPEFLGACFDAGLSWVHFPE
MSMEG_6584|M.smegmatis_MC2_155 -----------------------------PIPQFLAACYDAGLSWVHFPE
MAB_3122|M.abscessus_ATCC_1997 -----------------------------PVTDLLGAVYDAGLAWVHFPV
MMAR_1953|M.marinum_M -----------------------------DPREFLGARFDAGLAWVHFPV
TH_4197|M.thermoresistible__bu ----------------------------DQYRQWYPTFARSGLVVPTWAP
MAV_0587|M.avium_104 VRRRLGIDLTEVEDQRPQIAEAVARIAALPAEQRQAALAEAGLQAPHWPA
MUL_4144|M.ulcerans_Agy99 VRRRLDIDLSEVADLRPEIVAAVADVAALPEQKRQEALAEAGLLAPHWPA
MLBr_00737|M.leprae_Br4923 -----------------------------FPEEALAALNASGFNAIHVPE
. : :*: .
Mb1969c|M.bovis_AF2122/97 EYGGGGLSPMEQVVLAEEFARAGAPER-AENDLLGIDLLGNTLIALGSE-
Rv1934c|M.tuberculosis_H37Rv EYGGGGLSPMEQVVLAEEFARAGAPER-AENDLLGIDLLGNTLIALGSE-
Mflv_0344|M.gilvum_PYR-GCK GFGGLGVSRGLQAVADGILQGAGSPVP-LGLNPMGYGMAAPTVREHAQTD
Mvan_0394|M.vanbaalenii_PYR-1 GFGGLGLSRGLQAVADRILQGAGGPVP-LGLNPMGYGMAAPTVREHAQTD
MSMEG_6584|M.smegmatis_MC2_155 GMGGLGVSRGLQAVVDRILQGAGGPVP-LGLNPMGYGMAAPTIREHAQND
MAB_3122|M.abscessus_ATCC_1997 GLGGLDAPPALQAVSDTILRAAGVPDP-LFVNVIGYGMAAPTVLAHGQP-
MMAR_1953|M.marinum_M GFGGLDLPHTYQAQVDKQLAAAGAPPAGGGRNIIGIGMAAPTIAAFGTA-
TH_4197|M.thermoresistible__bu EYGGLGLAPATARAVERVLA----PLRLTRLNPLGLNNAAAALFSHGTE-
MAV_0587|M.avium_104 PYG-RGASPAEQLLIDQELAAAGVARP----DLVIGWWAAPTILEHGTP-
MUL_4144|M.ulcerans_Agy99 PYG-RGASPAEQLLIDQELAAAGVVRP----DLVIGWWAAPTILEHGTP-
MLBr_00737|M.leprae_Br4923 EYGGQGADSVAACIVIEEVARVDASAS---LIPAVNKLGTMGLILRGSE-
* . . : .
Mb1969c|M.bovis_AF2122/97 AQKRHFLPRILSGEHRWCQGFSEPEAGSDLASVRTRGVLDGD---EWVIN
Rv1934c|M.tuberculosis_H37Rv AQKRHFLPRILSGEHRWCQGFSEPEAGSDLASVRTRGVLDGD---EWVIN
Mflv_0344|M.gilvum_PYR-GCK DVRRQLLRPLATTEHIWCQLFSEPGAGSDLAGLATSAVLDGD---TWVVN
Mvan_0394|M.vanbaalenii_PYR-1 EVRHRLLRPLATTEEIWCQLFSEPGAGSDLAGLATSAVLDGD---TWVVN
MSMEG_6584|M.smegmatis_MC2_155 ELKKSWLRPLASTEHIWCQLFSEPGAGSDLAGLATSAVPDGD---DWVIN
MAB_3122|M.abscessus_ATCC_1997 ELIRRILRPLFTGEELWCQLFSEPGAGSDLAGLATRAVRDGD---EWVIN
MMAR_1953|M.marinum_M EQKQKFLRPLFTGEHLYCQLFSEPGAGSDLAAAATRAVRDPHRPLDWIVN
TH_4197|M.thermoresistible__bu EQRRRFLPPIVRNEEVWCQLFSEPGAGSDLASLATRAVPDGD---EWVVT
MAV_0587|M.avium_104 EQIERFVPGTLRGEFLWCQLFSEPGAGSDLASLRTKAVRTDG---GWLLT
MUL_4144|M.ulcerans_Agy99 EQIARFVPSTLRGDFLWCQLFSEPGAGSDLASLRTKAVRGDG---GWLLT
MLBr_00737|M.leprae_Br4923 ELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGD---DWILN
: . :** **** *. * . *::.
Mb1969c|M.bovis_AF2122/97 GHKIWTSAGTTANWIFLLARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVN
Rv1934c|M.tuberculosis_H37Rv GHKIWTSAGTTANWIFLLARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVN
Mflv_0344|M.gilvum_PYR-GCK GQKVWTSLAHRAKWGLLLARTDPNMPKHKGLTYFVIDMHGEGVQTRPLRQ
Mvan_0394|M.vanbaalenii_PYR-1 GQKVWTSLAHRAKWGLLLARTDPDVPKHKGLTYFVIDMHADGVQTRPLRQ
MSMEG_6584|M.smegmatis_MC2_155 GQKVWTSLAHRARWGLLLARTNPDVPKHKGLTYFVIDMHGPGVETRPLRQ
MAB_3122|M.abscessus_ATCC_1997 GQKVWTSGAHQARWALLVARSNPDVAKHRGLTYFVVDMTDPGVEVRPLRQ
MMAR_1953|M.marinum_M GQKVWTSMAQHAQMAILVARTDPDVPKHAGLTYFLCDMTQPGIDIRPLRQ
TH_4197|M.thermoresistible__bu GQKVWTTWADVADFAILLARTDPDAPKHAGITYFALDMHQPGVEVRPLRQ
MAV_0587|M.avium_104 GQKVWTSAAHKARWGVCLARTDPDAPKHKGITYFLVDMSAPGIEIRPLRE
MUL_4144|M.ulcerans_Agy99 GQKVWTSAAHKARWGVCLARTDPDAPKHKGITYFLLDMTAPGIEIRPLRE
MLBr_00737|M.leprae_Br4923 GFKCWITNGGKSTWYTVMAVTDPDKGAN-GISAFIVHKDDEGFSIGPKEK
* * * : . : :* ::*. : *:: : *. * :
Mb1969c|M.bovis_AF2122/97 AAGH--SSFSEVFLTDARTSAGNVVGRVGDGWSTAMTLLGFERGSHIAT-
Rv1934c|M.tuberculosis_H37Rv AAGH--SSFSEVFLTDARTSAGNVVGRVGDGWSTAMTLLGFERGSHIAT-
Mflv_0344|M.gilvum_PYR-GCK LTGH--AEFNEVYMTDARIPDTFRLGAVGDGWRVAMTTLMNERSALGGS-
Mvan_0394|M.vanbaalenii_PYR-1 LTGH--AEFNEVYMTDARIPDAYRLGAVGDGWRVAMTTLMNERSALGGS-
MSMEG_6584|M.smegmatis_MC2_155 MTGQ--AEFNEVYMTDARIPDAHRLGAVGDGWRVAMTTLMNERSALGGS-
MAB_3122|M.abscessus_ATCC_1997 MTGD--AEFNEVYLTDVRIPDAHRLGNEGDGWRVSMTTLMNERSALGGA-
MMAR_1953|M.marinum_M ITGE--AEFNEVFLTDIRVPDANRLGPEGGGWRVATTTLNNERVAIGSR-
TH_4197|M.thermoresistible__bu ITGE--AEFNEVFLDGARIPDAHRIGAVNDGWRVSASTLTSERQMVSGSG
MAV_0587|M.avium_104 ITGD--SLFNEVFLDNVFVPDEMVVGEVNDGWRLARTTLANERVAMASG-
MUL_4144|M.ulcerans_Agy99 ITGD--SLFNEVFLENVFIPDQMVVGAVNDGWRLARTTLANERVAMATG-
MLBr_00737|M.leprae_Br4923 KLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQ-
* : .*::: . :* . *: : : * *
Mb1969c|M.bovis_AF2122/97 ---AAIDFERDLQRLCELARDRGLHTDPRVRDGLAWCYARVQIMRYRGYR
Rv1934c|M.tuberculosis_H37Rv ---AAIDFERDLQRLCELARDRGLHTDPRVRDGLAWCYARVQIMRYRGYR
Mflv_0344|M.gilvum_PYR-GCK -GSR-RGAGTISD-AVALWTSRPDLHTPVLRDRLSSLWLRSEAQRLTSKR
Mvan_0394|M.vanbaalenii_PYR-1 -GSR-RGAGTVSD-AVALWASRPDLHTPVLRDRLTRLWLRAEAQRLTSER
MSMEG_6584|M.smegmatis_MC2_155 -GSR-RGAGTIAD-AVSLWASRPDLHTPVLRDRLTQLWLRSEAQRLTAER
MAB_3122|M.abscessus_ATCC_1997 -FDHGRGGGSIGN-ALNLWKQRPDLHTPELRAKLTNLFVRSEGNRYGTQM
MMAR_1953|M.marinum_M -TGVPREGGMIGK-VTEAWRAEPALRNPAMHDDMMRLWVEAEVLRLAGER
TH_4197|M.thermoresistible__bu SGGMGRLGGSSAERLIEVAKAHGRWDDPVVRTKVARLWAQEKIRGWTNDR
MAV_0587|M.avium_104 -----TALGNPMEELLELLSTLP--LDSAQQDRLGRLIVTAQTGALLDQR
MUL_4144|M.ulcerans_Agy99 -----TALGNPMEELLEVLAEPE--LDTGQQDRLARLIVATQTGALLDQR
MLBr_00737|M.leprae_Br4923 ---AVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAAR
. .
Mb1969c|M.bovis_AF2122/97 DLTLALTGRPPGAEAAITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNG
Rv1934c|M.tuberculosis_H37Rv DLTLALTGRPPGAEAAITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNG
Mflv_0344|M.gilvum_PYR-GCK SRAAATVGG-PGPEGSVGKLVGAELNQHIYEFCMDLLGPEGILYDGYGMG
Mvan_0394|M.vanbaalenii_PYR-1 SRASATVGG-PGPEGSVGKLVGAELNQHIYEFCMDLLGPEGILYGSYGMQ
MSMEG_6584|M.smegmatis_MC2_155 SRATATVGG-PGPEGSIGKLVGAELNQHIYQWCMDFLGPEGLLYDGYGLG
MAB_3122|M.abscessus_ATCC_1997 RIAAQGDAP-MGPEGSIGKLMGAELNQQIYDFCVELLGIEATLYASYDMR
MMAR_1953|M.marinum_M LRQQAASGQ-PGPEGAGMKVAFARLAQQISGFELELHPESGLQYDDWTLR
TH_4197|M.thermoresistible__bu VRAALSAGQTPGPASSIGKVHQATLNQQIQDLMVDLLGTAALAWEPSENP
MAV_0587|M.avium_104 IAQLAVGGQDPGAQSSVRKLIGVRYRQALAEYTMDVSEGGGLVHNR----
MUL_4144|M.ulcerans_Agy99 IAQLVMGGRDPGAQSSVRKLIGVRYRQALAEYMMDVSACGGLVENR----
MLBr_00737|M.leprae_Br4923 LIVYAAAARAERGEPDLG-FISAASKCFASDIAMEVTTDAVQLFGGAGYT
. . ::.
Mb1969c|M.bovis_AF2122/97 GARLVPEAGTPNSPACWMDELLYARAATIYAGSSQIQRNVIGERLLGLPK
Rv1934c|M.tuberculosis_H37Rv GARLVPEAGTPNSPACWMDELLYARAATIYAGSSQIQRNVIGERLLGLPK
Mflv_0344|M.gilvum_PYR-GCK D-----GDAADWRG-PIQQRFLRSRANTIEGGTSEVMRNILAERVLGLPG
Mvan_0394|M.vanbaalenii_PYR-1 DT-SSNGDAQDWRG-PIQQRFLRSRANTIEGGTSEVMRNILAERVLGLPG
MSMEG_6584|M.smegmatis_MC2_155 D-----GDGADWRG-PVQQRFLRSKANTIEGGTSEVMRNILGERILGLPG
MAB_3122|M.abscessus_ATCC_1997 R-----VVEDDRRA-DTMWAFLRSKANTIEGGTSDVMRNIIGERVLGLPG
MMAR_1953|M.marinum_M R-----PDTVDLTGRGPGYRYLRARGNSIEGGTSEILRNTISERVLGLPG
TH_4197|M.thermoresistible__bu D-----ALPREVHG------MMRSLANSTEGGTTDINKNILGERVLGLPK
MAV_0587|M.avium_104 ----------------AVYDFLNTRCLTIAGGTEQILLTVAAERLLGLPR
MUL_4144|M.ulcerans_Agy99 ----------------AVFDFLNTRCLTIAGGTEQILLTVAAERLLGLPR
MLBr_00737|M.leprae_Br4923 S------------DFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR---
: *: :: .. :*
Mb1969c|M.bovis_AF2122/97 EPRPEVLC--------
Rv1934c|M.tuberculosis_H37Rv EPRPEVLC--------
Mflv_0344|M.gilvum_PYR-GCK DLRADAGMAWKEIPRG
Mvan_0394|M.vanbaalenii_PYR-1 DLRADAGMPWKEVPRG
MSMEG_6584|M.smegmatis_MC2_155 DLRADAGMAWKEIPRG
MAB_3122|M.abscessus_ATCC_1997 DIRVDTDKAWKDVPRG
MMAR_1953|M.marinum_M EHRVDKTLAWKDLDR-
TH_4197|M.thermoresistible__bu EPDPGKGKPWKDIPRS
MAV_0587|M.avium_104 ----------------
MUL_4144|M.ulcerans_Agy99 ----------------
MLBr_00737|M.leprae_Br4923 ----------------