For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4263 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 4049374 - 4050522
length: 383

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4263--100% (383)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4185-7e-7439.79% (387) PUTATIVE putative acyl-CoA dehydrogenase, middle domain protein
M. thermoresistible (build 8)TH_3884-5e-6940.31% (387) PUTATIVE acyl-CoA dehydrogenase protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3590cfadE300.081.72% (383) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCKMflv_1481-0.087.66% (381) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3560cfadE300.081.72% (383) acyl-CoA dehydrogenase FADE30
M. leprae Br4923MLBr_00737fadE252e-2327.13% (387) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-0.079.79% (376) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_5049fadE300.084.47% (380) acyl-CoA dehydrogenase FadE30
M. avium 104MAV_0601-0.085.00% (380) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_6012-0.085.71% (392) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4125fadE300.083.95% (380) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1Mvan_5285-0.089.32% (384) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MAV_0601|M.avium_104                --------------MQDV--EEFRAEVRSWLADNLVGEFAALKGLGGPGR
Mflv_1481|M.gilvum_PYR-GCK          --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1       --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
TH_4263|M.thermoresistible__bu      --------------VIEV--HEFRAEVRQWLADNLVGEYAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                    :   . .:   .           *  :    .. 

Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MAV_0601|M.avium_104                EHEAFEERRAWNQHLAKAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1       EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
TH_4263|M.thermoresistible__bu      EHEAFEERLEWNRKLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYALAN
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                     .:  .        *  :* ..:  * *:**:*        . ** * .:

Mb3590c|M.bovis_AF2122/97           APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv        APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MMAR_5049|M.marinum_M               APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MUL_4125|M.ulcerans_Agy99           APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MAV_0601|M.avium_104                APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
Mflv_1481|M.gilvum_PYR-GCK          APDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAG
Mvan_5285|M.vanbaalenii_PYR-1       APDKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGAG
MSMEG_6012|M.smegmatis_MC2_155      APDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAG
TH_4263|M.thermoresistible__bu      APAKVNHLGEELLGPTLIEYGTPEQQQRFLPRILDVTELWAQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997      APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                    *. .:    ::*    **  *: : :::.** :     : . . **  **

Mb3590c|M.bovis_AF2122/97           SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
Rv3560c|M.tuberculosis_H37Rv        SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
MMAR_5049|M.marinum_M               SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MUL_4125|M.ulcerans_Agy99           SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MAV_0601|M.avium_104                SDLANVSTTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
Mflv_1481|M.gilvum_PYR-GCK          SDLANVSTTATLD----------GDEWVINGQKVWTSLAHWAQWCFVVAR
Mvan_5285|M.vanbaalenii_PYR-1       SDLANVSTTAVLDE--------EGRQWHINGQKVWTSLAHWAQWCFVVAR
MSMEG_6012|M.smegmatis_MC2_155      SDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVAR
TH_4263|M.thermoresistible__bu      SDLANVSTTAVLD----------GDQWVINGQKVWTSLAHWAQWCFVVAR
MAB_0597|M.abscessus_ATCC_1997      SDLANVSTSAVLD----------GGDWVINGQKVWTSLALQSQWCFVVAR
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKAD----------GDDWILNGFKCWITNGGKSTWYTVMAV
                                    ** *.: * *             .  * :** * * : .  : *  *:* 

Mb3590c|M.bovis_AF2122/97           TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Rv3560c|M.tuberculosis_H37Rv        TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MMAR_5049|M.marinum_M               TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MUL_4125|M.ulcerans_Agy99           TEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTD
MAV_0601|M.avium_104                TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Mflv_1481|M.gilvum_PYR-GCK          TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTA
Mvan_5285|M.vanbaalenii_PYR-1       TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTD
MSMEG_6012|M.smegmatis_MC2_155      TEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDARTE
TH_4263|M.thermoresistible__bu      TERGSKRHHGLSYLLVPLDQPGVEIRPIVQLTGD--SEFNEVFFDNARTD
MAB_0597|M.abscessus_ATCC_1997      TEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
MLBr_00737|M.leprae_Br4923          TDP-DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
                                    *:  ..   *:* ::*  :: ...* *  :  *   :  .*::**..*  

Mb3590c|M.bovis_AF2122/97           ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
Rv3560c|M.tuberculosis_H37Rv        ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
MMAR_5049|M.marinum_M               ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
MUL_4125|M.ulcerans_Agy99           ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
MAV_0601|M.avium_104                ASMVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYARELSNLAELARR
Mflv_1481|M.gilvum_PYR-GCK          ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAEK
Mvan_5285|M.vanbaalenii_PYR-1       ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
MSMEG_6012|M.smegmatis_MC2_155      AGLVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
TH_4263|M.thermoresistible__bu      ASMVVGEPGDGWRVAMGTLTFER---GVSTLGQQIQYRRELEGVVELAKR
MAB_0597|M.abscessus_ATCC_1997      ADLVVGEPGDGWRVAMGTLTFER---GVSTLGNQITYARELSRLAELAKS
MLBr_00737|M.leprae_Br4923          GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
                                    .. ::* ** *::.*:.** . *   *..::*            .   . 

Mb3590c|M.bovis_AF2122/97           TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
Rv3560c|M.tuberculosis_H37Rv        TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
MMAR_5049|M.marinum_M               TGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
MUL_4125|M.ulcerans_Agy99           TGAADDPFIREHLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
MAV_0601|M.avium_104                NGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
Mflv_1481|M.gilvum_PYR-GCK          TGAADDPLIRERLVRSWAGLKAMRSYALATMD---VEKPGQDNISKLLWA
Mvan_5285|M.vanbaalenii_PYR-1       TGAADDPLIRERLTRSWAGLKAMRSYALATMD---VEQPGMDNVSKLLWA
MSMEG_6012|M.smegmatis_MC2_155      TGAADDPLIRERLVQSWTGLQAMRSYALATMD---VEQPGQDNVSKLLWA
TH_4263|M.thermoresistible__bu      TGAIDDPLIRERLTRSWVGLRTMRSYALATMD---DERPGQDNISKLLWA
MAB_0597|M.abscessus_ATCC_1997      NGAADDPAIRERLAQAYVGMRTMRAYALATMD---EERPGQDNVSKLLWA
MLBr_00737|M.leprae_Br4923          FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD--LGFISA
                                     .   ..    ::  :  .::.  :  :.       *:   *    :: *

Mb3590c|M.bovis_AF2122/97           NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
Rv3560c|M.tuberculosis_H37Rv        NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
MMAR_5049|M.marinum_M               NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
MUL_4125|M.ulcerans_Agy99           NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
MAV_0601|M.avium_104                NWHRALGELAMDVIGKPGMTMPDGEFD---EWQRLFLFTRADTIYGGSNE
Mflv_1481|M.gilvum_PYR-GCK          NWHRELGEIAMDIEGAAGLTLPDGEFS---EWQRLYLFSRSDTIYGGSNE
Mvan_5285|M.vanbaalenii_PYR-1       NWHRELGEIAMDVQGMAGLTLPGGEFD---EWQRLYLFSRSDTIYGGSNE
MSMEG_6012|M.smegmatis_MC2_155      NWHRELGEIAMDVQGMAGLTLENGEFD---EWQRLYLFSRADTIYGGSNE
TH_4263|M.thermoresistible__bu      NWHRELGEIAMDVVGMAGLTLTDGDFD---EWQRLYLFSRSDTIYGGSNE
MAB_0597|M.abscessus_ATCC_1997      NWHRDLGELAMEIIGTSTLLTNAGEMD---EWQRLFLFSRADTIYGGSNE
MLBr_00737|M.leprae_Br4923          ASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQ
                                      :   .::**::   .      .        :*:   ::   ** *:*:

Mb3590c|M.bovis_AF2122/97           IQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        IQRNIIAERVLGLPREAKG
MMAR_5049|M.marinum_M               IQRNIIAERVLGLPREAKG
MUL_4125|M.ulcerans_Agy99           IQRNIIAERVLGLPREAKG
MAV_0601|M.avium_104                IQRNIIAERVLGLPREVKG
Mflv_1481|M.gilvum_PYR-GCK          IQRNIIAERVLGLPREARH
Mvan_5285|M.vanbaalenii_PYR-1       IQRNIIAERVLGLPREAKG
MSMEG_6012|M.smegmatis_MC2_155      IQRNIIAERVLGLPREVKG
TH_4263|M.thermoresistible__bu      IQRNIIAERVLGLPREPKG
MAB_0597|M.abscessus_ATCC_1997      IQRNIISERVLGLPREAR-
MLBr_00737|M.leprae_Br4923          IQRVVMSRALLR-------
                                    *** :::. :*