For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1934c (fadE17)

annotation: PROBABLE ACYL-CoA DEHYDROGENASE FADE17
coordinates: 2184959 - 2186188
length: 409

DVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHEREEFARHWRRALAGAGLVAVSWPTEYGGGGLSP
MEQVVLAEEFARAGAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPEAGSDLA
SVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGH
SSFSEVFLTDARTSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGLHTDPRV
RDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNG
GARLVPEAGTPNSPACWMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv1934c fadE17 - 100% (409) PROBABLE ACYL-CoA DEHYDROGENASE FADE17
M. tuberculosis H37Rv Rv3560c fadE30 4e-85 43.18% (403) acyl-CoA dehydrogenase FADE30
M. tuberculosis H37Rv Rv3562 fadE31 5e-65 36.83% (410) acyl-CoA dehydrogenase FADE31

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1969c fadE17 0.0 100.00% (409) acyl-CoA dehydrogenase FADE17
M. gilvum PYR-GCK Mflv_1481 - 3e-83 43.18% (403) acyl-CoA dehydrogenase domain-containing protein
M. leprae Br4923 MLBr_00737 fadE25 9e-29 28.18% (401) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 1e-87 44.22% (398) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_2862 fadE17 0.0 78.43% (408) acyl-CoA dehydrogenase FadE17
M. avium 104 MAV_0601 - 2e-85 43.64% (401) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_6012 - 4e-81 42.09% (411) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4263 - 5e-84 42.18% (403) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_2892 fadE17 1e-180 78.55% (387) acyl-CoA dehydrogenase FadE17
M. vanbaalenii PYR-1 Mvan_4006 - 0.0 79.95% (404) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv1934c|M.tuberculosis_H37Rv        -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPP--H
Mb1969c|M.bovis_AF2122/97           -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPP--H
MMAR_2862|M.marinum_M               -----------MDVAYPPEAEEFRERVRAFLDEHLPCGWSGPGALAV--Q
MUL_2892|M.ulcerans_Agy99           ------------------------------MDEHLPCGWSGPGALAV--Q
Mvan_4006|M.vanbaalenii_PYR-1       -----------MDVDYPPQAEAFRDRIRALLAEHLPPDWSGGGALAP--E
Mflv_1481|M.gilvum_PYR-GCK          ----------------MIEVQKFRAEVRDWLAENLVGDFAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      ----------------MIEVQEFRAEVRQWLADNLVGDFAALKGLGGPGR
TH_4263|M.thermoresistible__bu      ----------------VIEVHEFRAEVRQWLADNLVGEYAALKGLGGPGR
MAV_0601|M.avium_104                ----------------MQDVEEFRAEVRSWLADNLVGEFAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          --------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVD
                                                                                      

Rv1934c|M.tuberculosis_H37Rv        EREEFARH--WRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
Mb1969c|M.bovis_AF2122/97           EREEFARH--WRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
MMAR_2862|M.marinum_M               DRKAFAAR--WRQLLVAAGLIAVSWPKEYGGGGYSPVEQVVLAEEFARAG
MUL_2892|M.ulcerans_Agy99           DRKAFAAR--WRQLLVAAGLIAVSWPKEYGGGGYSPVEQVVLAEEFARAG
Mvan_4006|M.vanbaalenii_PYR-1       ERAAVARR--WRQSLAAAGLVAVSWPKAYGGAGLSVIEQVVLDEEFARAG
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
TH_4263|M.thermoresistible__bu      EHEAFEERLEWNRKLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYALAN
MAV_0601|M.avium_104                EHEAFEERRAWNQHLAKAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          QRARFPEEA--LAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                    ::  .  .      *  :*  .:  *  :** *        . ** * . 

Rv1934c|M.tuberculosis_H37Rv        APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
Mb1969c|M.bovis_AF2122/97           APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
MMAR_2862|M.marinum_M               APEREENDLFGVDLLGNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEPE
MUL_2892|M.ulcerans_Agy99           APEREENDLFGVDLLCNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEPE
Mvan_4006|M.vanbaalenii_PYR-1       APERAENDLLGIQLLGNTLIALGTEEQKRHFLPRILSAEDRWCQGFSEPE
Mflv_1481|M.gilvum_PYR-GCK          APDKVNH--LGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPG
MSMEG_6012|M.smegmatis_MC2_155      APDKVNH--FGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPN
TH_4263|M.thermoresistible__bu      APAKVNH--LGEELLGPTLIEYGTPEQQQRFLPRILDVTELWAQGYSEPG
MAV_0601|M.avium_104                APDKVNH--FGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPG
MAB_0597|M.abscessus_ATCC_1997      APHKVNH--LGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMG--LILRGSEELKKQVLPSLAAEGAMASYALSERE
                                    *.            :   **  *:   :::.** :       . . **  

Rv1934c|M.tuberculosis_H37Rv        AGSDLASVRTRGVLDGDE----------WVINGHKIWTSAGTTANWIFLL
Mb1969c|M.bovis_AF2122/97           AGSDLASVRTRGVLDGDE----------WVINGHKIWTSAGTTANWIFLL
MMAR_2862|M.marinum_M               AGSDLASVRTRAVLDGDQ----------WVINGQKIWTSAGSTANWIFVL
MUL_2892|M.ulcerans_Agy99           AGSDLASVRTRAVLDGDQ----------WVINGQKIWTSAGSTANWIFVL
Mvan_4006|M.vanbaalenii_PYR-1       AGSDLASVRTRAVLDDDE----------WVINGQKIWTSAGPTANWIFVL
Mflv_1481|M.gilvum_PYR-GCK          AGSDLANVSTTATLDGDE----------WVINGQKVWTSLAHWAQWCFVV
MSMEG_6012|M.smegmatis_MC2_155      AGSDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVV
TH_4263|M.thermoresistible__bu      AGSDLANVSTTAVLDGDQ----------WVINGQKVWTSLAHWAQWCFVV
MAV_0601|M.avium_104                AGSDLANVSTTAELDGDQ----------WVINGQKVWTSLAHLSQWCFVV
MAB_0597|M.abscessus_ATCC_1997      AGSDLANVSTSAVLDGGD----------WVINGQKVWTSLALQSQWCFVV
MLBr_00737|M.leprae_Br4923          AGSDAASMRTRAKADGDD----------WILNGFKCWITNGGKSTWYTVM
                                    **** *.: * .   ..           *::** * * : .  : *  ::

Rv1934c|M.tuberculosis_H37Rv        ARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDAR
Mb1969c|M.bovis_AF2122/97           ARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDAR
MMAR_2862|M.marinum_M               ARTDPVAPKHQGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADAR
MUL_2892|M.ulcerans_Agy99           ARTDPVAPKHQGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADAR
Mvan_4006|M.vanbaalenii_PYR-1       ARTDTEAPKHKGLSLLLVPIDQPGVVVRPIVNAAGH--ASFSEVFFTDAR
Mflv_1481|M.gilvum_PYR-GCK          ARTEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDAR
MSMEG_6012|M.smegmatis_MC2_155      ARTEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDAR
TH_4263|M.thermoresistible__bu      ARTERGSKRHHGLSYLLVPLDQPGVEIRPIVQLTGD--SEFNEVFFDNAR
MAV_0601|M.avium_104                ARTEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDAR
MAB_0597|M.abscessus_ATCC_1997      ARTEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNAR
MLBr_00737|M.leprae_Br4923          AVTDP-DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCR
                                    * *:       *:* ::*  :: .. : *  :  *   :  .*::: ..*

Rv1934c|M.tuberculosis_H37Rv        TSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDR
Mb1969c|M.bovis_AF2122/97           TSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDR
MMAR_2862|M.marinum_M               TGVANVVGEVGSGWTAAMSLLGFERGAQATTGAIDFARDLSRLCDLARAR
MUL_2892|M.ulcerans_Agy99           TGVANVVGEVGSGWTAAMSLLGFERGAQATTGAIDFARDLSRLCDLARAR
Mvan_4006|M.vanbaalenii_PYR-1       TPAVNVVGRVGDGWPAAMTVLGFERGSQVTTAAINFGREMDRLRELARDR
Mflv_1481|M.gilvum_PYR-GCK          TAADLVVGEPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAEKT
MSMEG_6012|M.smegmatis_MC2_155      TEAGLVVGQPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKRT
TH_4263|M.thermoresistible__bu      TDASMVVGEPGDGWRVAMGTLTFERGVSTLGQQIQYRRELEGVVELAKRT
MAV_0601|M.avium_104                TDASMVVGQPGDGWRVAMGTLTFERGVSTLGQQIRYARELSNLAELARRN
MAB_0597|M.abscessus_ATCC_1997      TSADLVVGEPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSN
MLBr_00737|M.leprae_Br4923          IPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDR
                                         ::*. * *: .*:  * . *               .     :.  

Rv1934c|M.tuberculosis_H37Rv        GLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIW
Mb1969c|M.bovis_AF2122/97           GLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIW
MMAR_2862|M.marinum_M               GLDSDPRIRDRLAWCYSRTQIMRYRGYRSLTWALNGLLPGAEAAISKVIW
MUL_2892|M.ulcerans_Agy99           GLDSDPRIRDRLAWCYSRTQIMRYRGYCSLTWALNGVLPGAEAAISKVIW
Mvan_4006|M.vanbaalenii_PYR-1       GLHTDARIRDGLAWCYSRVQIMRFQGYRGLTSLLAGQRPGREAAISKVVW
Mflv_1481|M.gilvum_PYR-GCK          GAADDPLIRERLVRSWAGLKAMRSYALATMDVEKPG-----QDNISKLLW
MSMEG_6012|M.smegmatis_MC2_155      GAADDPLIRERLVQSWTGLQAMRSYALATMDVEQPG-----QDNVSKLLW
TH_4263|M.thermoresistible__bu      GAIDDPLIRERLTRSWVGLRTMRSYALATMDDERPG-----QDNISKLLW
MAV_0601|M.avium_104                GAADDPFIRERLTRAWTGLRAMRSYALATMDVEQPG-----QDNVSKLLW
MAB_0597|M.abscessus_ATCC_1997      GAADDPAIRERLAQAYVGMRTMRAYALATMDEERPG-----QDNVSKLLW
MLBr_00737|M.leprae_Br4923          KQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLG-FIS
                                        :.               *:  .   :     .     :  :  .: 

Rv1934c|M.tuberculosis_H37Rv        SEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELL
Mb1969c|M.bovis_AF2122/97           SEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELL
MMAR_2862|M.marinum_M               SEYFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPACWMDELL
MUL_2892|M.ulcerans_Agy99           SEYFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPACWMDELL
Mvan_4006|M.vanbaalenii_PYR-1       SEFFRRYTELAVEILGLEALSPAGPGNGEALIVPEPGTPNSAACWMDELL
Mflv_1481|M.gilvum_PYR-GCK          ANWHRELGEIAMDIEGAAGLTLPD---------------GEFSEWQRLYL
MSMEG_6012|M.smegmatis_MC2_155      ANWHRELGEIAMDVQGMAGLTLEN---------------GEFDEWQRLYL
TH_4263|M.thermoresistible__bu      ANWHRELGEIAMDVVGMAGLTLTD---------------GDFDEWQRLYL
MAV_0601|M.avium_104                ANWHRALGELAMDVIGKPGMTMPD---------------GEFDEWQRLFL
MAB_0597|M.abscessus_ATCC_1997      ANWHRDLGELAMEIIGTSTLLTNA---------------GEMDEWQRLFL
MLBr_00737|M.leprae_Br4923          AASKCFASDIAMEVTTDAVQLFGGAG------------YTSDFPVERFMR
                                    :       ::*:::                          .         

Rv1934c|M.tuberculosis_H37Rv        YARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC----------
Mb1969c|M.bovis_AF2122/97           YARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC----------
MMAR_2862|M.marinum_M               YARAATIYAGSSQIQRNVIGEQLLGLPKEPRREAVH----------
MUL_2892|M.ulcerans_Agy99           YARAATIYAGSSQIQRNVIGEQLLGLPKEPRREAVH----------
Mvan_4006|M.vanbaalenii_PYR-1       YARASTIYAGSSQIQRNVIGEQLLGLPREPRVPAGRVPEPAGRGSN
Mflv_1481|M.gilvum_PYR-GCK          FSRSDTIYGGSNEIQRNIIAERVLGLPREARH--------------
MSMEG_6012|M.smegmatis_MC2_155      FSRADTIYGGSNEIQRNIIAERVLGLPREVKG--------------
TH_4263|M.thermoresistible__bu      FSRSDTIYGGSNEIQRNIIAERVLGLPREPKG--------------
MAV_0601|M.avium_104                FTRADTIYGGSNEIQRNIIAERVLGLPREVKG--------------
MAB_0597|M.abscessus_ATCC_1997      FSRADTIYGGSNEIQRNIISERVLGLPREAR---------------
MLBr_00737|M.leprae_Br4923          DAKITQIYEGTNQIQRVVMSRALLR---------------------
                                     ::   ** *:.:*** ::.. :*

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv1934c	fadE17	-	100% (409)	PROBABLE ACYL-CoA DEHYDROGENASE FADE17
M. tuberculosis H37Rv	Rv3560c	fadE30	4e-85	43.18% (403)	acyl-CoA dehydrogenase FADE30
M. tuberculosis H37Rv	Rv3562	fadE31	5e-65	36.83% (410)	acyl-CoA dehydrogenase FADE31