For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2795 | - | - | 100% (405) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 5e-08 | 33.33% (93) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. thermoresistible (build 8) | TH_4015 | - | 7e-08 | 28.12% (160) | PUTATIVE - |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1998c | - | 1e-24 | 25.81% (372) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0013 | - | 1e-104 | 49.88% (405) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1963c | mce3R | 1e-24 | 25.81% (372) | transcriptional repressor (probably TETR-family) MCE3R |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 44.64% (56) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 2e-13 | 25.65% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5559 | - | 3e-97 | 48.35% (395) | putative regulatory protein |
| M. avium 104 | MAV_0110 | - | 1e-120 | 56.78% (391) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0815 | - | 1e-104 | 50.25% (394) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3597 | - | 3e-97 | 48.35% (395) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0719 | - | 1e-100 | 49.36% (391) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1998c|M.bovis_AF2122/97 --------------------------------------------------
Rv1963c|M.tuberculosis_H37Rv --------------------------------------------------
TH_2795|M.thermoresistible__bu --------------------------------------------------
MAV_0110|M.avium_104 --------------------------------------------------
MMAR_5559|M.marinum_M --------------------------------------------------
MUL_3597|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0815|M.smegmatis_MC2_155 MHAPENSSTGQGAMALRNDTTASRLSMLRGWSMCVLDQMTPTYVNDRSPW
Mvan_0719|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0013|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mb1998c|M.bovis_AF2122/97 -----------------------MASVAQPVRRRPKDRKKQILDQAVGLF
Rv1963c|M.tuberculosis_H37Rv -----------------------MASVAQPVRRRPKDRKKQILDQAVGLF
TH_2795|M.thermoresistible__bu ----------------MSAAGS---DAHRNGRHRPKNRKALIARASADAF
MAV_0110|M.avium_104 ------------------------------MKRRPKDRKVQIARAATDAF
MMAR_5559|M.marinum_M -----MAGTDSGYGEVMSAASVSPGAAADGIRRRPKDRKAQIARAAAESF
MUL_3597|M.ulcerans_Agy99 -----MAGTDSGYGEVMSAASVSPGAAADGIRRRPKDRKAQIARAAAESF
MSMEG_0815|M.smegmatis_MC2_155 VRAFDRIGGPVYRDHMARTPLGPTTSGSVAVRRRPKDRKAQIARASAEAF
Mvan_0719|M.vanbaalenii_PYR-1 ---------------MA------STADDHGIRRRPKDRKAQIARASAEAF
Mflv_0013|M.gilvum_PYR-GCK MAVRKKPTRARGAGRSVRVCRMAASVGVRDARRRPKDRKQQIARASAEAF
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mb1998c|M.bovis_AF2122/97 IERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSAR
Rv1963c|M.tuberculosis_H37Rv IERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSAR
TH_2795|M.thermoresistible__bu GAQGYHAVSMEEIAARVGISPAALYRHSQGKYDLFRDSVLGLGQLLVDAT
MAV_0110|M.avium_104 SELGYHAVSMENIAARVGISAAALYRHSQGKYDLFREVFLALGQQLVDAT
MMAR_5559|M.marinum_M SAQGYHAVSMETIAAKVGVSAPALYRHYAGKYELFRGAVLALSQQLVDCT
MUL_3597|M.ulcerans_Agy99 SAQGYHAVSMETIAAKVGVSAPALYRHYAGKYELFRGAVLALSQQLVDCT
MSMEG_0815|M.smegmatis_MC2_155 SALGYHGVSMEAIASRVGISAAALYRHYSSKYELFRDAVLNLGQQLVDCT
Mvan_0719|M.vanbaalenii_PYR-1 SALGYYGVSMEMIASRVGISAAALYRHYSSKYELFRDAVLNLGQQLVDGT
Mflv_0013|M.gilvum_PYR-GCK SELGYHAVSMEDIASRVGVTAASLYRHYSGKYDLFRAAVLNLGEQLVSAT
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mb1998c|M.bovis_AF2122/97 RLTEG-----ETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNED
Rv1963c|M.tuberculosis_H37Rv RLTEG-----ETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNED
TH_2795|M.thermoresistible__bu DFGDDVDP---AEDPHGLLAALVDALINVTIANRTAGGLYRWEGRYLREP
MAV_0110|M.avium_104 AFADDLPA---DADPGETLSALTTALIDTTIVNRTAGGLYRWEGRYLRGD
MMAR_5559|M.marinum_M QLDD-------SDDPAQLLDGLIASLIEVTLDNRLSGGLYRWQSRYLRAE
MUL_3597|M.ulcerans_Agy99 QLDD-------SDDPAQLLARLIASLIEVTLDNRLSGGLYRWQSRYLRAE
MSMEG_0815|M.smegmatis_MC2_155 AFADTADAPENSEDAREQLRLLAAALTDTSLANRESGGLYRWEARYLNED
Mvan_0719|M.vanbaalenii_PYR-1 AGIE-------GDDPQVVLDRLVSALTDTALANRGSGGLYRWEGRYLRGD
Mflv_0013|M.gilvum_PYR-GCK AFADDES----GDSPEELWERIVAALADAAIKTRASGGLYRWEARFLQES
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mb1998c|M.bovis_AF2122/97 DRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHS
Rv1963c|M.tuberculosis_H37Rv DRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHS
TH_2795|M.thermoresistible__bu DRDILERQIQLVNRRLQRPLRVMRPELGSRQRWTLTASALSAIGSIADHS
MAV_0110|M.avium_104 DQRKLAEQIKVINRRLQRPLIKLRPKLTSRQRWILSAATLSVIGSITDHR
MMAR_5559|M.marinum_M DQAAVADVLKVVNRRIQKPLTVIRPSLRPAQRWMLSAGVLSVIGSIVDHP
MUL_3597|M.ulcerans_Agy99 DQAAVADVLKVVNRRIQKPLTVIRASLRPAQRWMLSAGVLSVIGSIVDHP
MSMEG_0815|M.smegmatis_MC2_155 DQAALNAQMRTVHHRIQRPLQQLRPELISRERWMLSTATLSVIGSVVDHR
Mvan_0719|M.vanbaalenii_PYR-1 DQATLLQQIHTVHHRIHRPLSALRPELTARQRSTLSTAALSIVGSIVDHR
Mflv_0013|M.gilvum_PYR-GCK DQAISNEQIRLVNRRLQRPLSALRPELDSRQRWTVTASVLSAIGSICDHR
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mb1998c|M.bovis_AF2122/97 LSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYET
Rv1963c|M.tuberculosis_H37Rv LSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYET
TH_2795|M.thermoresistible__bu APLSVPGIRSFLASVVEDLL-AADLPTPRRRRAPDPPPPRVTLAAGIYEC
MAV_0110|M.avium_104 SRLGNAEIRATLSDIAAAVL-KAELPTQRGRGSEPARAPTLTSAAGSYEL
MMAR_5559|M.marinum_M ARLAADEIRALLGEAASAIV-CAELPEPGDVAVRKASWRIFAEDASVYET
MUL_3597|M.ulcerans_Agy99 ARLAADEIRALLGEAASAIV-CAELPEPGDVAVRKASWRIFAEDASVYET
MSMEG_0815|M.smegmatis_MC2_155 GKLPAGQIREVLGEIVESVL-AADLPELPELGAAAAPATTPVVSAAKYEA
Mvan_0719|M.vanbaalenii_PYR-1 AKLPAAQVHALIAQISRAVL-GAELSADPPRYPPDVVPARPTAEPSKYEA
Mflv_0013|M.gilvum_PYR-GCK AKLPVNDMRRLLVSLARRLR-DADLPPVSAREKPGRRAAPSVGPAGEYEA
MAB_4541|M.abscessus_ATCC_1997 ---------------MTNLIPESETPNKRERAKADRR-----------DQ
MLBr_00815|M.leprae_Br4923 -------MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQ
Mb1998c|M.bovis_AF2122/97 LLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRR
Rv1963c|M.tuberculosis_H37Rv LLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRR
TH_2795|M.thermoresistible__bu VLHESIQMFHERGFRDTGMDDIAAAVGVPTTGIYRYFPGKADILAASLRR
MAV_0110|M.avium_104 LLHESMRLFNERGYRETGMEDIAAAVGIPVASIYQYFPGKAAILAVYYRR
MMAR_5559|M.marinum_M LLHASMVLFKDRGYAQTSMAQIASASGVPVSGIYRYFSGKCEILATGLRR
MUL_3597|M.ulcerans_Agy99 LLHASMVLFKDRGYAQTSMAQIASAAGVPVSGIYRYFSGKCEILATGLRR
MSMEG_0815|M.smegmatis_MC2_155 LLNESMRLFNKNGYRDTTMEDIAAAVGMPASGIYRYFSGKADILAAGFRR
Mvan_0719|M.vanbaalenii_PYR-1 LLTASMQLFDRNGYRDTTMEDIASAVGMPTSGIYKYFSGKSDILATIFRR
Mflv_0013|M.gilvum_PYR-GCK ILAAALRLFHEHGFRETGMDDIASAIGLPASTIYRYFSGKSAVLSTIYRR
MAB_4541|M.abscessus_ATCC_1997 LLRAAARLLAMRGYARVRLEDLGSAVGISGPAIYRHFPNKEALLVDLLTD
MLBr_00815|M.leprae_Br4923 LLIVASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLER
:* . :: .*: . ::. *:. . :*: *..* :
Mb1998c|M.bovis_AF2122/97 LDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSH
Rv1963c|M.tuberculosis_H37Rv LDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSH
TH_2795|M.thermoresistible__bu AVDRTSQDLARITAATADPHTALTQLVRAYLDQFRERPALAYVQHTERRN
MAV_0110|M.avium_104 AADQLSADLSSILATSSDPEQALARLIEAYVTRSFANPELACVYYTERHN
MMAR_5559|M.marinum_M AADRVSGQLSPIVGALTEPRQALTLLIDAYVATSFANPELAAVYYTERAN
MUL_3597|M.ulcerans_Agy99 AADRVSGQLSPIVGALTEPRQALTLLIDAYVATSFANPELAAVYYTERAN
MSMEG_0815|M.smegmatis_MC2_155 AADRLSADMAEILAAGGEPEDVLAALIDDYVTRSFDRPELEHVYYTERLN
Mvan_0719|M.vanbaalenii_PYR-1 AADRVSAELASVVATMSDPEEALTAVIDGYVQRSFDQPELECVYYSERLN
Mflv_0013|M.gilvum_PYR-GCK AADRVSGDMGAILAMAPDERTAVGQLIDAYVWRTFAEPELAYVYYAEQLN
MAB_4541|M.abscessus_ATCC_1997 VSRRLLEGGMTVAAAASSPAEALDGLIDFHLDFALNESDLIRVQDRDLDS
MLBr_00815|M.leprae_Br4923 HMNNLVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNI
. : : .. : :
Mb1998c|M.bovis_AF2122/97 ASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDV
Rv1963c|M.tuberculosis_H37Rv ASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDV
TH_2795|M.thermoresistible__bu LPESEARVVERIEQSLVDSWARLVTEQRPELTVATARYAVYCAFALVTDL
MAV_0110|M.avium_104 LPETDAVLLYNIQRSTVESWARLAVAARPELTLGRARYAVHAAFALAVDI
MMAR_5559|M.marinum_M LTPADQMLLHNIQLSTIDSWVRLLTSVRPSLSATRARFLVHAAMALVVDL
MUL_3597|M.ulcerans_Agy99 LTPADQMLLHNIQLSTIDSWVRLLTSVRPSLSATRARFLVHAAMALVVDL
MSMEG_0815|M.smegmatis_MC2_155 MTPADQKILRDLQRSAVESWVNVVMPVRPHWSAGQARFAVHAAMALVIDL
Mvan_0719|M.vanbaalenii_PYR-1 MSAADQRIVRDLQRSTVESWVELVVAVRPEWSAAEARFAVHAAMALVVDL
Mflv_0013|M.gilvum_PYR-GCK VPAEDRAALHNIQRSIVEGWARQVVAARPDLSVREARFAVHAGLGLVVDI
MAB_4541|M.abscessus_ATCC_1997 LPENARRQVRQYQRRYVEAWVQVLCRSQQGLDESDARIKAHAAFGLMNST
MLBr_00815|M.leprae_Br4923 TEPRVAAQVRVATESCIDAVFALIS-ADSRLDPHRARMVAVGLVGISVDC
.* . ..: .
Mb1998c|M.bovis_AF2122/97 ARTWHLTR---YAGVADEISGLALAILTSGAGNLLRA-------------
Rv1963c|M.tuberculosis_H37Rv ARTWHLTR---YAGVADEISGLALAILTSGAGNLLRA-------------
TH_2795|M.thermoresistible__bu GRLTDSH----ASPSAQAAVQHLMEVVLLG-G------------------
MAV_0110|M.avium_104 GRLVYPN----TGAPASTTVRRLMEVTVLG-RPAAASRDGLRGAGRQRR-
MMAR_5559|M.marinum_M GRMVDPQDSAGQSAYVQACVRELMELTLFGPTPAQADAAPPPPPGRRRRG
MUL_3597|M.ulcerans_Agy99 GRMVDPQDSAGQSAYVQACVRELMELTLFGPTPAQADAAPPPPPGRRRRG
MSMEG_0815|M.smegmatis_MC2_155 GRLMGYR----NSEQARAVVSTMVDLVLLGRYRLRTALPAR---------
Mvan_0719|M.vanbaalenii_PYR-1 GRLMRYE----NSEEARETVSGLVDMTLLGRYRLRATLPAK---------
Mflv_0013|M.gilvum_PYR-GCK GRLERFA----DTESSRRLIGRLLRVLLLPEHA-----------------
MAB_4541|M.abscessus_ATCC_1997 PYSAGRS----APSQTRTVLRQMVVAALRS--------------------
MLBr_00815|M.leprae_Br4923 ARYWLDTN---RPISKSDAVEGTVQFAWGGLSHVPLTRL-----------
:
Mb1998c|M.bovis_AF2122/97 ----------
Rv1963c|M.tuberculosis_H37Rv ----------
TH_2795|M.thermoresistible__bu ----------
MAV_0110|M.avium_104 ----------
MMAR_5559|M.marinum_M SSNPGHVARR
MUL_3597|M.ulcerans_Agy99 SSNPGHVARR
MSMEG_0815|M.smegmatis_MC2_155 ----------
Mvan_0719|M.vanbaalenii_PYR-1 ----------
Mflv_0013|M.gilvum_PYR-GCK ----------
MAB_4541|M.abscessus_ATCC_1997 ----------
MLBr_00815|M.leprae_Br4923 ----------