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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2634 | - | - | 100% (428) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3186 | - | 2e-53 | 34.51% (426) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_2591 | - | 1e-49 | 33.33% (429) | PUTATIVE feruloyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0172 | fadD5 | 3e-45 | 31.97% (416) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_0027 | - | 9e-62 | 35.65% (418) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0166 | fadD5 | 2e-45 | 32.21% (416) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 2e-38 | 30.24% (420) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4559 | - | 5e-54 | 32.69% (413) | putative long-chain-fatty-acid CoA ligase |
| M. marinum M | MMAR_0409 | fadD5 | 6e-46 | 31.22% (410) | fatty-acid-CoA ligase FadD5 |
| M. avium 104 | MAV_1867 | - | 1e-173 | 72.27% (422) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_4065 | - | 3e-56 | 35.64% (404) | feruloyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_0650 | fadD8 | 6e-40 | 31.03% (406) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_0943 | - | 2e-60 | 35.87% (421) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2634|M.thermoresistible__bu -------------------MTA----LTVGDIVSDNAHR-----------
MAV_1867|M.avium_104 -------------------MCADDLDLTLGDIVTDNAVR-----------
MAB_4559|M.abscessus_ATCC_1997 --------------------------MQFTQWLHRALQQ-----------
MSMEG_4065|M.smegmatis_MC2_155 ------------------------MTMYLTQGLHRAVQQ-----------
Mb0172|M.bovis_AF2122/97 --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
Rv0166|M.tuberculosis_H37Rv --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
MMAR_0409|M.marinum_M --------------------MTAELASHLPQAA-HALEQPYLARRQNWVN
Mflv_0027|M.gilvum_PYR-GCK ------------------------MFHNLADIVRSHGRN-----------
Mvan_0943|M.vanbaalenii_PYR-1 ------------------------MIHNLADIIRVHGRE-----------
MUL_0650|M.ulcerans_Agy99 --------------------MSDDLLRNPTHNGHLLVGALER--------
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
TH_2634|M.thermoresistible__bu --------FPDVVAYRMGERTLTHAELYDRATRLVSAMVAAGVRRQDRIA
MAV_1867|M.avium_104 --------FGDVPAYKLGSRMVTHAQLHDRAVQLVSAMAAAGVRRQDRVA
MAB_4559|M.abscessus_ATCC_1997 --------YPDRLITIDQGREHTVEQFADRVARLSAGLRANGVRPGDRVG
MSMEG_4065|M.smegmatis_MC2_155 --------TPGATMTVFGERRRTFLEVADRVARLAGALRALGVRAGDRVA
Mb0172|M.bovis_AF2122/97 QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
Rv0166|M.tuberculosis_H37Rv QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
MMAR_0409|M.marinum_M QLERHAMMQPRATAIRYLGHTVTWADLRYRVAALAGSLSRRGVGFGDRVM
Mflv_0027|M.gilvum_PYR-GCK --------RPDAPALIVGDRTVSYRELDERSNRTAQAFSRTGVGPGDRVA
Mvan_0943|M.vanbaalenii_PYR-1 --------RPGAPALVVGDRTVTYGELDDRSSRAAQAFAQAGVGVGDRVA
MUL_0650|M.ulcerans_Agy99 --------HKNRPVLFLGDTTLTGGQLAERISQYIQAFEALGAGTGVTVG
MLBr_02546|M.leprae_Br4923 LPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIA
: :. .: *. :
TH_2634|M.thermoresistible__bu ILSRNSIEFGEVMAATHLSGIILATVNFRLTGGEVRDVINRVRPKIVFVG
MAV_1867|M.avium_104 VLSRNSVEFGEVMAATHLSGVIMATVNFRLSPDEVLDVLKRVSPSMVFCS
MAB_4559|M.abscessus_ATCC_1997 MLSLNSDRYIEYLTAVPWLGAALNAVNIRWSLAEIGYSLRESGTRVLLVD
MSMEG_4065|M.smegmatis_MC2_155 MLAQNSDRYHEYLLAVPWANGVLNPVNIRWTPAEIAYSLEDSGTKVMFVD
Mb0172|M.bovis_AF2122/97 ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCAAHVMLTE
Rv0166|M.tuberculosis_H37Rv ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCVAHVMLTE
MMAR_0409|M.marinum_M ILMLNRTEFVESVLAANMLGAIAVPLNFRLTPSEIAFLVEDCAPRLVITE
Mflv_0027|M.gilvum_PYR-GCK FVERNGIEFFDVAFGSAKLGAVAVPVNWRLTAPEMRHVIADCGASVVVVG
Mvan_0943|M.vanbaalenii_PYR-1 FVDKNGAEFFEVTFGLAKVGAVGVPVNWRLAAPEMRHIIADSGAKIVVVG
MUL_0650|M.ulcerans_Agy99 LLSLNRPEVLMILGASQARGYRRTALHPLGSLDDHAYVLYDAGASALIID
MLBr_02546|M.leprae_Br4923 ILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYD
.: * . . :: : : . :.
TH_2634|M.thermoresistible__bu DE--FAPMVADLAGQLTSTPLLVCVG-----DGHSAMTDYEEFVASGRAG
MAV_1867|M.avium_104 DE--FALVAAGLAPQLASPPLLVSIGG----SGRTGMLDFEEFVGGGDGG
MAB_4559|M.abscessus_ATCC_1997 DT--FKAAAAPLRAACACLETVIYCG---AGPAPQDMIGYEDLLASH-EP
MSMEG_4065|M.smegmatis_MC2_155 DS--FARMLPAIKDAWAELSTVIYAG---EASPPAGTLAYEELIDKS-DP
Mb0172|M.bovis_AF2122/97 AA--LAPVAIGVRNIQPLLSVIVVAG---GSSQDS-VFGYEDLLNEAGDV
Rv0166|M.tuberculosis_H37Rv AA--LAPVAIGVRNIQPLLSVIVVAG---GSSQDS-VFGYEDLLNEAGDV
MMAR_0409|M.marinum_M EV--LAQVAVGVREIAPALSTIVVAG---GASDPT-VVGYDELISETGDP
Mflv_0027|M.gilvum_PYR-GCK QE--FTGRIEAIADD-LDVEVVVIGK---HRHWPT----FDDLLAAAPAV
Mvan_0943|M.vanbaalenii_PYR-1 QD--FAGHLEAIEDG-LDADIVVIGD---HPRWPA----FDDWVASHPPV
MUL_0650|M.ulcerans_Agy99 PNPMFVERALGLLEKVDSLEQVLTIGPVPEALEDRAVDLSAEAAKYQPKP
MLBr_02546|M.leprae_Br4923 DE--YTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSSAP
:
TH_2634|M.thermoresistible__bu DVALRARPEDIACLIFTSGTTGASKCCILGQTEHR-RVLFTMNNEMRSGS
MAV_1867|M.avium_104 RLPFAARPDDIACLLFTSGTTGASKCCILGQAELR-RVAFTMNVEMRTGS
MAB_4559|M.abscessus_ATCC_1997 IDDTRTGGDSLLGVFYTGGTTGNPKGVMLSHNNVLASAMGSLSTGNFLTR
MSMEG_4065|M.smegmatis_MC2_155 VDDARRGGDELAGLFYTGGTTGFPKGVMLSHANLLTSTYGLLTPGFAFRP
Mb0172|M.bovis_AF2122/97 HEPVDIPNDSPALIMYTAGTTGRPKGAVLTHANLTGQAMTALYTSGANIN
Rv0166|M.tuberculosis_H37Rv HEPVDIPNDSPALIMYTSGTTGRPKGAVLTHANLTGQAMTALYTSGANIN
MMAR_0409|M.marinum_M PEPVDIPNDSPALIMYTSGTTGRPKGAVLTHTNLTGQVMTALYTGGANIN
Mflv_0027|M.gilvum_PYR-GCK DPGVVTGPDDLVFLMYTSGTTGAPKGVMLSNANVVCKTAGVGGP-WKFDA
Mvan_0943|M.vanbaalenii_PYR-1 DPGVVTGPDDVVLLMYTSGTTGAPKGVMLSNTNYVYKTGGVAGP-WQFDA
MUL_0650|M.ulcerans_Agy99 LVVADLPPNHIGGLTYTGGTTGKPKGVIGTAGNITAMTS-IQLAEWEWPE
MLBr_02546|M.leprae_Br4923 APKVRKRAS---IIILTSGTTGTPKGANR-NTPASLAPLGGILSKVPFRA
. : *.**** .*
TH_2634|M.thermoresistible__bu DDQILINMPMFHIGAMAMLGGMHARGGTVVLQQQ--FDPDEAVRLIAEHR
MAV_1867|M.avium_104 SDRGLINMPMFHVGAMAIVAGLHARGGSVVLQQQ--FDAGEAVQLITDER
MAB_4559|M.abscessus_ATCC_1997 GGRLLHSAPMFHMADFSAVLAGNLSGSTHVIVPS--FSPQGVLDAIVAHD
MSMEG_4065|M.smegmatis_MC2_155 GGICLHAAPMFHLADLMSWSAGLLQGGRHVFIPS--FEPVTVMQAIAQHQ
Mb0172|M.bovis_AF2122/97 SDVGFVGVPLFHIAGIGNMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEK
Rv0166|M.tuberculosis_H37Rv SDVGFVGVPLFHIAGIGNMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEK
MMAR_0409|M.marinum_M SDVGFIGVPFFHIAGIGNMLSGMLLGVPTVIYPLGAFNPGQLLDVLEAER
Mflv_0027|M.gilvum_PYR-GCK DSVSLAVMPLFHMAGFGWALAGLWEGAVTVVLRD--VDPGAILDAVARHR
Mvan_0943|M.vanbaalenii_PYR-1 DAVSLAVMPLFHMAGSGWALAGLWQGATTVVLRD--VEPAAILDAIARHR
MUL_0650|M.ulcerans_Agy99 HPRFLMCTPLSHAG-AAFFTPTLVKGGEMIVLAK--FDPGEVLRVIEEQR
MLBr_02546|M.leprae_Br4923 HEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRR--FKPATVLEDIEKHQ
: *: * * :. ... : : .
TH_2634|M.thermoresistible__bu ITVLHLAPVMLSALLD--AVTD-TGSLESLHTVVYAAAPMTMNILERALA
MAV_1867|M.avium_104 ITLLHLAPVMLRALLD--EITD-PRGLDCLRTVIYSAAPMTVHTLRRALS
MAB_4559|M.abscessus_ATCC_1997 VQDMLLVPTMIQMLVD--HPGAAQLDLSGIRSITYGASVISEAVLQRATR
MSMEG_4065|M.smegmatis_MC2_155 VTDALLVPTMIQKLID--HPDINRYDLTSFRALFYAASAIPQALLERAMK
Mb0172|M.bovis_AF2122/97 VTGIFLVPAQWQAVCT--EQQARPRDLR-LRVLSWGAAPAPDALLRQMSA
Rv0166|M.tuberculosis_H37Rv VTGIFLVPAQWQAVCT--EQQARPRDLR-LRVLSWGAAPAPDALLRQMSA
MMAR_0409|M.marinum_M VSGIFLVPAQWQAVCA--EQQARPRELS-LRVMSWGAAPAPDALLRQMSE
Mflv_0027|M.gilvum_PYR-GCK VTNMLLVPAVIQFLLD--TTGLDDTDLSRLRIVVYGASPITDDVLMRGID
Mvan_0943|M.vanbaalenii_PYR-1 ITNMLLVPAVIQFLLD--TDGVAEVDLSTLRVIVYGASPISDDVLVRGIE
MUL_0650|M.ulcerans_Agy99 ITATMLVPSMLYALMD--HPDPHTRDLSSLETVYYGASAINPVRLAEAID
MLBr_02546|M.leprae_Br4923 ATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALE
:.* : * :. : ..: .
TH_2634|M.thermoresistible__bu LMPSVGFLNLYGQTEAIVSGLPRELHAGDP----EALRSVGFPFPGNRVR
MAV_1867|M.avium_104 VLPRTGFLNLYGQTEAIVSGLPRELHDADSPDAADALRSVGFPFPGVRVR
MAB_4559|M.abscessus_ATCC_1997 VFPNARFTQAYGMTEVSPVATLLLPDDHDDPA---LLRSAGRAAPHCEVR
MSMEG_4065|M.smegmatis_MC2_155 VFPNAEFVQGYGMTELSPLATLLSPDDHQKPR---LLRSAGRAAPSAEVR
Mb0172|M.bovis_AF2122/97 TFPETQILAAFGQTEMSPVTCMLLGEDAIAK-----RGSVGRVIPTVAAR
Rv0166|M.tuberculosis_H37Rv TFPETQILAAFGQTEMSPVTCMLLGEDAIAK-----RGSVGRVIPTVAAR
MMAR_0409|M.marinum_M VFPGTQIMAAFGQTEMSPVTCMLLGEDAIRK-----RGSVGKVIPTVSAR
Mflv_0027|M.gilvum_PYR-GCK RFG-GIFAQVYGMTESTGSVTQLDGDEHLPQ----LLRSCGRPYPWVQIR
Mvan_0943|M.vanbaalenii_PYR-1 RFG-PIFAQVYGMTETTGSITQLDGPDHVPA----LLRSCGRPYPWVQIR
MUL_0650|M.ulcerans_Agy99 RFG-PIFAQYYGQSEAPMVITYLPKADHDEK----RLTSCGRPTLFARVA
MLBr_02546|M.leprae_Br4923 ELG-PVIYNMYGSTEIAFATIAGPKDLQINS------ATVGPVVKGVKVK
: : :* :* : *
TH_2634|M.thermoresistible__bu IVDDDGADVPVGEAGEIVVQSDSLFRGYWDDQAATLATLR-DGWCHTGDV
MAV_1867|M.avium_104 IVGDDGRDVLPGEAGEIVVRSDSRFRGYWDDPVATLATLR-DGWCHTGDV
MAB_4559|M.abscessus_ATCC_1997 IVDPDDNEVPRGEIGEVIVKGDNVMLGYWELPEESAAAIR-DGWMHTGDA
MSMEG_4065|M.smegmatis_MC2_155 IVDPDGNEVPRRTVGEVAVRGGNVMLGYWNKPQETAAAIR-DGWMHTGDA
Mb0172|M.bovis_AF2122/97 VVDQNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAFA-GGWFHSGDL
Rv0166|M.tuberculosis_H37Rv VVDQNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAFA-GGWFHSGDL
MMAR_0409|M.marinum_M VVDDEMNDVPIGQVGEIVYRAPTLMSGYWNNPDATAEAFA-GGWFHSGDL
Mflv_0027|M.gilvum_PYR-GCK VVDPTGRDVAPGTVGEVWTRSDQNMLGYWNNPEATAATLTPDGWLRTGDA
Mvan_0943|M.vanbaalenii_PYR-1 IVDETGADAVAGTVGEVWTRSEQNMLGYWNNPDATASTLTADGWLKTGDA
MUL_0650|M.ulcerans_Agy99 LLGEDGKPVPQGEPGEICVSGPLLAGGYWNKPDDTAQTFR-DGWLHTGDM
MLBr_02546|M.leprae_Br4923 ILDDSGKEVPRGQVGRIFVGNAFPFEGYTGG----GGKQIIDGLLSSGDV
::. . *.: * .* :**
TH_2634|M.thermoresistible__bu GRFDERGLLYLVDRKKDVIITGGENVYSPEGRTPFCG-------------
MAV_1867|M.avium_104 GRFDHRGLLYLVDRKKDVIITGGENVYSPEVEEVLGGCEGVAACAVVGAP
MAB_4559|M.abscessus_ATCC_1997 GRMDDRGYVYIVDRIKDMVVTGGENVYSAEVENALAKHPAVAACAVIGIP
MSMEG_4065|M.smegmatis_MC2_155 AYMDDDGYIYVVDRIKDMIITGGENVYSAEVENAVVQHPSVAACAVIGVP
Mb0172|M.bovis_AF2122/97 VRMDSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRA
Rv0166|M.tuberculosis_H37Rv VRMDSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRA
MMAR_0409|M.marinum_M VRMDEDGYVWVVDRKKDMIISGGENVYCAEVENVLASHPSIVEVAVIGRA
Mflv_0027|M.gilvum_PYR-GCK GYLDRDGYLYLHDRIKDMIVSGAENVYPAEVENVLMTHPAVTDVAVIGIP
Mvan_0943|M.vanbaalenii_PYR-1 GYVDDDGYLFLHDRIKDMIVSGGENVYPVEVENVLMTHPAVADAAVIGVP
MUL_0650|M.ulcerans_Agy99 AREDEDGFYFIVDRVKDMIVTGGFNVFPREVEDVVAEHSAVAQVCVVGAP
MLBr_02546|M.leprae_Br4923 GYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVD
* . :: .* .:::::*. *:: * . .
TH_2634|M.thermoresistible__bu --------------------------------------------------
MAV_1867|M.avium_104 DEKWGEAVCAVVVPTPG-------ATPTLEAVQEFVRSSLAGYKVPRRLV
MAB_4559|M.abscessus_ATCC_1997 DEQWGERVHAVVVKQAQ-------SECCDGDLQEHCREHIANYKVPRSFE
MSMEG_4065|M.smegmatis_MC2_155 DADWGERVHAVVVLQPG-------AELAACQIREHAKRLIAGYKCPRSIE
Mb0172|M.bovis_AF2122/97 DEKWGEVPIAVAAVTN--------DDLRIEDLGEFLTDRLARYKHPKALE
Rv0166|M.tuberculosis_H37Rv DEKWGEVPIAVAAVTN--------DDLRIEDLGEFLTDRLARYKHPKALE
MMAR_0409|M.marinum_M DEKWGEVPIAVAAVTK--------DHLRIEDLDEYLTERLARYKHPKALE
Mflv_0027|M.gilvum_PYR-GCK DTRWGEAVKAVVVAG---------APVTEAELIAFAREQLAGFKLPKSVD
Mvan_0943|M.vanbaalenii_PYR-1 DRRWGEAVKAVVVAARG-------AQLTEAELIAFARDRIGGFKLPKSVD
MUL_0650|M.ulcerans_Agy99 DEKWGEAVTAVVVLRADAARDDAAIETMTAEIQAAVKQRKGSVQSPKQVV
MLBr_02546|M.leprae_Br4923 DKEWGARLRAFVVKKQD-------ATIDEDAIKAYVRDHLARYKVPREVI
TH_2634|M.thermoresistible__bu -----------------------------------------------
MAV_1867|M.avium_104 VVSDLPVLASGKVDKKRLRAEIAAAAAD-------------------
MAB_4559|M.abscessus_ATCC_1997 FVDELPLSGAGKILKRVLRQKY-----WESRDAGVS-----------
MSMEG_4065|M.smegmatis_MC2_155 FVNALPLSGAGKVLKRELRERH-----LGARERDRGSLP--------
Mb0172|M.bovis_AF2122/97 IVDALPRNPAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL
Rv0166|M.tuberculosis_H37Rv IVDALPRNPAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL
MMAR_0409|M.marinum_M IVDALPRNPSGKVLKTELRLRYGVGVYSESRSVSRSFEFREGS----
Mflv_0027|M.gilvum_PYR-GCK FVDALPRNPSGKLLKRQLREPY-----WTDEDRHIG-----------
Mvan_0943|M.vanbaalenii_PYR-1 FVDVLPRNPSGKLLKRALREPY-----WDGADRHIG-----------
MUL_0650|M.ulcerans_Agy99 VVDSLPLTGLGKPDKKAVRARF-----WEGAGRAVG-----------
MLBr_02546|M.leprae_Br4923 FLEELPRNPTGKVLKRELRDFEVH-----------------------