For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2591 | - | - | 100% (526) | feruloyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_2787 | - | 0.0 | 60.31% (519) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3186 | - | 3e-84 | 39.80% (505) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0172 | fadD5 | 9e-75 | 35.59% (503) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_4559 | - | 0.0 | 68.39% (522) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv0166 | fadD5 | 9e-75 | 35.79% (503) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 2e-63 | 31.41% (519) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4559 | - | 1e-80 | 35.39% (503) | putative long-chain-fatty-acid CoA ligase |
| M. marinum M | MMAR_0409 | fadD5 | 2e-80 | 36.58% (503) | fatty-acid-CoA ligase FadD5 |
| M. avium 104 | MAV_5018 | - | 2e-77 | 36.45% (502) | acyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_2883 | - | 0.0 | 86.38% (514) | acyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_4126 | fadD3 | 2e-63 | 33.73% (501) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_2882 | - | 0.0 | 83.04% (519) | acyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2883|M.smegmatis_MC2_155 --------------------------------------MLASTRSHALGD
Mvan_2882|M.vanbaalenii_PYR-1 --MIGGAGSSGRLLLSGTRRDCRNHATPTVGRMDDLHAVLASARSHALGD
TH_2591|M.thermoresistible__bu --------------------------------MDDLHAVVASARGHALGD
Mflv_4559|M.gilvum_PYR-GCK ------------------------------MPEDLLAAQIRRVRSQTVGD
Mb0172|M.bovis_AF2122/97 --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
Rv0166|M.tuberculosis_H37Rv --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
MMAR_0409|M.marinum_M --------------------MTAELASHLPQAA-HALEQPYLARRQNWVN
MAV_5018|M.avium_104 ---------------------MLSLTAQLAHHPTQANEQPYLSRRQNWVN
MAB_4559|M.abscessus_ATCC_1997 ---------------------------------------------MQFTQ
MUL_4126|M.ulcerans_Agy99 ----------------------------------------MTSDPRTVPT
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
MSMEG_2883|M.smegmatis_MC2_155 IPRRSARRCPDKVAIIDGDVTLTFAEFEHHVDRAAAALQDNGFGVGDRVA
Mvan_2882|M.vanbaalenii_PYR-1 IPRRSARKQPDKIAIIDGDVCLSFAEFERLVDRAAAALSDNGFGVGDRLA
TH_2591|M.thermoresistible__bu IPRRSARRHPDKVAIIDGDVTWTFAEFEHWVDRAAAALSDHGFAPGDRVA
Mflv_4559|M.gilvum_PYR-GCK IPRRSARRHPHKLAIVDGTTRLTFAELDAHVDRVASALRDSGFGKGDRIA
Mb0172|M.bovis_AF2122/97 QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
Rv0166|M.tuberculosis_H37Rv QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
MMAR_0409|M.marinum_M QLERHAMMQPRATAIRYLGHTVTWADLRYRVAALAGSLSRRGVGFGDRVM
MAV_5018|M.avium_104 QLERHALMQPNATALRFLGKGLTWGELHGRVRALADALSRRGVGFGDRVM
MAB_4559|M.abscessus_ATCC_1997 WLHRALQQYPDRLITIDQGREHTVEQFADRVARLSAGLRANGVRPGDRVG
MUL_4126|M.ulcerans_Agy99 ALDRLVRRLPNHDALVTDERSFTVSELNDEVYRAAAALIELGVKPAARVG
MLBr_02546|M.leprae_Br4923 LPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIA
* : :: . : .* *. . :
MSMEG_2883|M.smegmatis_MC2_155 VLAHNCWQYAVLAFATARAGVVLVPVNFMLTAEEICYILGHSRAGGFLVE
Mvan_2882|M.vanbaalenii_PYR-1 LLAHNCWQYAVLAFATARAGVVLVPINFMLTAEEISFILGHSQVTGFVVE
TH_2591|M.thermoresistible__bu VLSRNCRQFAVLAFATARAGVVLVPINFMLTAEEISYILGHCGARGFLVE
Mflv_4559|M.gilvum_PYR-GCK LLSHNCWQYAVLAFATARAGVVMVPVNFMLGPDEIAFILGHSKVTGFVVE
Mb0172|M.bovis_AF2122/97 ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCAAHVMLTE
Rv0166|M.tuberculosis_H37Rv ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCVAHVMLTE
MMAR_0409|M.marinum_M ILMLNRTEFVESVLAANMLGAIAVPLNFRLTPSEIAFLVEDCAPRLVITE
MAV_5018|M.avium_104 VLMLNRPEFMESVLAINMLGAIAVPLNFRLTAAEIAFLVQDCQARVVITE
MAB_4559|M.abscessus_ATCC_1997 MLSLNSDRYIEYLTAVPWLGAALNAVNIRWSLAEIGYSLRESGTRVLLVD
MUL_4126|M.ulcerans_Agy99 IWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAM
MLBr_02546|M.leprae_Br4923 ILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYD
: * : . *. :* : ..
MSMEG_2883|M.smegmatis_MC2_155 ADLVPTAEAAMRLGGS--VTTTAALVLPGQGLPAGWTDFDRWLQTDS-PA
Mvan_2882|M.vanbaalenii_PYR-1 ADLVPTAEAAMQLAGN--VATGAALVPPGQSLPDGWTDFAQWLQTDS-TA
TH_2591|M.thermoresistible__bu ADLVPTAEAAMRLGGS--VTTTAALVLPGQALPPGWTDFDRWLQTTS-PA
Mflv_4559|M.gilvum_PYR-GCK TALVPVADEAMAAAGEDCAVTTRIAITSGDPVPAGWQDYAHWSQSAATPA
Mb0172|M.bovis_AF2122/97 AALAPVAIGVRNIQPL----LSVIVVAG-GSSQDSVFGYEDLLNEAGDVH
Rv0166|M.tuberculosis_H37Rv AALAPVAIGVRNIQPL----LSVIVVAG-GSSQDSVFGYEDLLNEAGDVH
MMAR_0409|M.marinum_M EVLAQVAVGVREIAPA----LSTIVVAG-GASDPTVVGYDELISETGDPP
MAV_5018|M.avium_104 AVLAPVATGVRDIESL----LDTVVVAG-GSSDDAVLGYDDLIDETGAAH
MAB_4559|M.abscessus_ATCC_1997 DTFKAAAAPLRAACAC----LETVIYCGAGPAPQDMIGYEDLLASH-EPI
MUL_4126|M.ulcerans_Agy99 GHFLGSDRVAGLDRKALPALRHIVRIPIEEPDGTWDEFIETGTDTGAVTA
MLBr_02546|M.leprae_Br4923 DEYTKVVSKAEPALGK----LRALGVNPDEEEPPGSTDETLAELIARSSS
MSMEG_2883|M.smegmatis_MC2_155 PAPYVADDQMIRLMYTSGTESHPKGAMHSTRSLMGNYISSIIAG-SMEGT
Mvan_2882|M.vanbaalenii_PYR-1 PNPHIDDDQLIRLMYTSGTESHPKGAQHSSRSLMGNYVSTIIAG-SMESA
TH_2591|M.thermoresistible__bu PHPYVADDQMIRLMYTSGTESRPKGAMHSSRSLMGNYVSTIIAG-SMESG
Mflv_4559|M.gilvum_PYR-GCK PAVEIADDDVLRLMYTSGTESRPKGVMHTSRSLMWQYISSIVAG-SMSGE
Mb0172|M.bovis_AF2122/97 EPVDIPNDSPALIMYTAGTTGRPKGAVLTHANLTGQAMTALYTSGANINS
Rv0166|M.tuberculosis_H37Rv EPVDIPNDSPALIMYTSGTTGRPKGAVLTHANLTGQAMTALYTSGANINS
MMAR_0409|M.marinum_M EPVDIPNDSPALIMYTSGTTGRPKGAVLTHTNLTGQVMTALYTGGANINS
MAV_5018|M.avium_104 QPVDIPNDAAALIMYTSGTTGRPKGAVLTHTNLTGQTMTGLYTNGADINN
MAB_4559|M.abscessus_ATCC_1997 DDTRTGGDSLLGVFYTGGTTGNPKGVMLSHNNVLASAMGSLSTGNFLTRG
MUL_4126|M.ulcerans_Agy99 RAAAVSPDDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANG-KITAD
MLBr_02546|M.leprae_Br4923 APAPKVRKRASIIILTSGTTGTPKGANRNTPASLAP-LGGILSKVPFRAH
. :: *.** . .**.
MSMEG_2883|M.smegmatis_MC2_155 DIEIHSLPLYHCAQMDNFFITDIYLGATSIILPRP--EPELVLRTIEKYG
Mvan_2882|M.vanbaalenii_PYR-1 DIEIHSLPLYHCAQLDNFLITDVYLGATSIIVSRP--DPELVLRTIEKHE
TH_2591|M.thermoresistible__bu DVEIHSLPLYHCAQLDNFLITDVYLGATSIILPRP--DPELVLRTIERHR
Mflv_4559|M.gilvum_PYR-GCK DVEIHSMPLYHCAQLDNFLITDVYLGATSIILPGP--DPEAILRTIEAEQ
Mb0172|M.bovis_AF2122/97 DVGFVGVPLFHIAGIG-NMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEK
Rv0166|M.tuberculosis_H37Rv DVGFVGVPLFHIAGIG-NMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEK
MMAR_0409|M.marinum_M DVGFIGVPFFHIAGIG-NMLSGMLLGVPTVIYPLGAFNPGQLLDVLEAER
MAV_5018|M.avium_104 DVGFIGVPFFHIAGIG-NMLTGLLLGIPTVIYPLGAFEPGQLLDVLAAEK
MAB_4559|M.abscessus_ATCC_1997 GRLLHSAPMFHMADFS-AVLAGNLSGSTHVIVPS--FSPQGVLDAIVAHD
MUL_4126|M.ulcerans_Agy99 DRHLCINPFFHNFGYKAGILACLQTGAT--LFPHLTFDPLRTLQAIERHR
MLBr_02546|M.leprae_Br4923 EVTLLPAPMFHALGYLHATLA-MFLGSTLVLRRR--FKPATVLEDIEKHQ
: *::* :: * . : .* * :
MSMEG_2883|M.smegmatis_MC2_155 VTNYFAPPTVWISLLRSPV--FDQVDLTSLRKGYYGASAMPVEILAEMRE
Mvan_2882|M.vanbaalenii_PYR-1 VTNYFAPPTVWISLLRSPV--FDQVDLSSLRKGYYGASAMPVEILAEMRE
TH_2591|M.thermoresistible__bu VTNYFAPPTVWISLLRSPV--FDTVDLSSLRKGYYGASAMPAEILAEIRD
Mflv_4559|M.gilvum_PYR-GCK VTNFFAPPTVWIALLRCPA--FDRYDLTSLRKGYYGASAMPREILHELRD
Mb0172|M.bovis_AF2122/97 VTGIFLVPAQWQAVCTEQQ--ARPRDLR-LRVLSWGAAPAPDALLRQMSA
Rv0166|M.tuberculosis_H37Rv VTGIFLVPAQWQAVCTEQQ--ARPRDLR-LRVLSWGAAPAPDALLRQMSA
MMAR_0409|M.marinum_M VSGIFLVPAQWQAVCAEQQ--ARPRELS-LRVMSWGAAPAPDALLRQMSE
MAV_5018|M.avium_104 VTGIFLVPAQWQAVCAEQR--ARPRDLK-LRVISWGAAPAPDALLREMSA
MAB_4559|M.abscessus_ATCC_1997 VQDMLLVPTMIQMLVDHPG--AAQLDLSGIRSITYGASVISEAVLQRATR
MUL_4126|M.ulcerans_Agy99 ITVLPGPPTIYQTLLDHPA--RDDYDLSSLRFAVTGAATVPVVLVERMQS
MLBr_02546|M.leprae_Br4923 ATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALE
*. : :* :* ..: : .
MSMEG_2883|M.smegmatis_MC2_155 RLPNLRLWNFYGQTEMAPLASALGP--DEQDAHAGAAGRPVINVETAILD
Mvan_2882|M.vanbaalenii_PYR-1 RLPNLRLWNFYGQTEMAPLASALGP--DEQDAHAGSAGRPVINVETAILD
TH_2591|M.thermoresistible__bu RLPGLRLWNFYGQTEMAPLATALGP--DEQDAHAGAAGRPVTNVETVILD
Mflv_4559|M.gilvum_PYR-GCK RLPNVSLWNFYGQTEIAPLASSLGP--DEQDRHGGAAGRPAVNVETAILD
Mb0172|M.bovis_AF2122/97 TFPETQILAAFGQTEMSPVTCMLLG--EDAIAKRGSVGRVIPTVAARVVD
Rv0166|M.tuberculosis_H37Rv TFPETQILAAFGQTEMSPVTCMLLG--EDAIAKRGSVGRVIPTVAARVVD
MMAR_0409|M.marinum_M VFPGTQIMAAFGQTEMSPVTCMLLG--EDAIRKRGSVGKVIPTVSARVVD
MAV_5018|M.avium_104 MFPGTQILAAFGQTEMSPVTCMLLG--EDAIRKRGSVGKVIPTVAARVVD
MAB_4559|M.abscessus_ATCC_1997 VFPNARFTQAYGMTEVSPVATLLLPDDHDDPALLRSAGRAAPHCEVRIVD
MUL_4126|M.ulcerans_Agy99 ELDIDIVLTAYGLTEANGMGTMCRAD-DDALTVATTCGRPFADFELRIG-
MLBr_02546|M.leprae_Br4923 ELG-PVIYNMYGSTEIAFATIAGPK---DLQINSATVGPVVKGVKVKILD
: . :* ** : : * :
MSMEG_2883|M.smegmatis_MC2_155 DDNRPVPPGEVGEIAHRSPHLMLGYLDDEAKTAEAFRGG-WFHSGDLGYY
Mvan_2882|M.vanbaalenii_PYR-1 DDNSPVAPGVVGEIAHRSPHLMLGYLDDDAKTAESFRGG-WFHSGDLGYY
TH_2591|M.thermoresistible__bu DDGAVLPAGTVGEIAHRSPHLMLGYYDDPAKTAEAFRGG-WFHSGDLGYF
Mflv_4559|M.gilvum_PYR-GCK DSDNPVPPGTVGEIAHRSPHLMVGYLDDPQRTAEAFRGD-WFHSGDLGYY
Mb0172|M.bovis_AF2122/97 QNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAFAGG-WFHSGDLVRM
Rv0166|M.tuberculosis_H37Rv QNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAFAGG-WFHSGDLVRM
MMAR_0409|M.marinum_M DEMNDVPIGQVGEIVYRAPTLMSGYWNNPDATAEAFAGG-WFHSGDLVRM
MAV_5018|M.avium_104 ENMNDVPVGEVGEIVYRAPTLMSGYWNNPEATAEAFAGG-WFHSGDLVRM
MAB_4559|M.abscessus_ATCC_1997 PDDNEVPRGEIGEVIVKGDNVMLGYWELPEESAAAIRDG-WMHTGDAGRM
MUL_4126|M.ulcerans_Agy99 --------PDTGEVLLRGPNVMLGYLDDPRATAAAIDADGWLHTGDIGVL
MLBr_02546|M.leprae_Br4923 DSGKEVPRGQVGRIFVGNAFPFEGYTG---GGGKQIIDG-LLSSGDVGYF
*.: : * . : . : :**
MSMEG_2883|M.smegmatis_MC2_155 DEHGLLHVVDRKKDMIKTGGENVASREVEEAVYRHPAVEEVAVFGLPHPT
Mvan_2882|M.vanbaalenii_PYR-1 DGHGLLHVVDRKKDMIKTGGENVASREVEEVIYRHSAVEEVAVFGLPHPV
TH_2591|M.thermoresistible__bu DEHGMLHVVDRKKDMINTGGENVASREVEEVIYRHPAVEEVAVFGLPHPT
Mflv_4559|M.gilvum_PYR-GCK DEFGLLHVVDRKKDMIKSGGENVASREVEEVLYQHDDVQEAAVFGLPHPV
Mb0172|M.bovis_AF2122/97 DSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRADEK
Rv0166|M.tuberculosis_H37Rv DSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRADEK
MMAR_0409|M.marinum_M DEDGYVWVVDRKKDMIISGGENVYCAEVENVLASHPSIVEVAVIGRADEK
MAV_5018|M.avium_104 DEDGYVWVVDRKKDMIISGGENIYCAEVENVLASHPDIVEVAVIGRAHEK
MAB_4559|M.abscessus_ATCC_1997 DDRGYVYIVDRIKDMVVTGGENVYSAEVENALAKHPAVAACAVIGIPDEQ
MUL_4126|M.ulcerans_Agy99 DEAGNLRITDRLKDMYICGGFNVYPAEVEQVLARLDGVADVAVIGIPDHR
MLBr_02546|M.leprae_Br4923 DEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKE
* . : : .* .:* ** *: *:*: : : :.:* .
MSMEG_2883|M.smegmatis_MC2_155 WVEAVVAAVVTRDGAELTEDELLTHCRSCLAGFKTPKQVFFVESLPKNPS
Mvan_2882|M.vanbaalenii_PYR-1 WVEAVVAAVVVRDGMEVTEDELASHCRAHLAGFKTPKQVYFVDSLPKNPS
TH_2591|M.thermoresistible__bu WVEAVVAAVVTRNGMTLGEEELLGHCREHLAGFKTPKQVFFVDSLPKNPS
Mflv_4559|M.gilvum_PYR-GCK WVEAVVAAVVPREGRVLDPDAVIAHCRSRLAGFKTPKQIFTVAELPKNPS
Mb0172|M.bovis_AF2122/97 WGE-VPIAVAAVTNDDLRIEDLGEFLTDRLARYKHPKALEIVDALPRNPA
Rv0166|M.tuberculosis_H37Rv WGE-VPIAVAAVTNDDLRIEDLGEFLTDRLARYKHPKALEIVDALPRNPA
MMAR_0409|M.marinum_M WGE-VPIAVAAVTKDHLRIEDLDEYLTERLARYKHPKALEIVDALPRNPS
MAV_5018|M.avium_104 WGE-VPIAVAAVANDNLALEDLDEFLTERLARYKHPKALEIVDALPRNPA
MAB_4559|M.abscessus_ATCC_1997 WGERVHAVVVKQAQSECCDGDLQEHCREHIANYKVPRSFEFVDELPLSGA
MUL_4126|M.ulcerans_Agy99 LGEVGRAFIVARPGFNLDEKSVIDYTREHLANFKAPRSVRFVDTLPRNAG
MLBr_02546|M.leprae_Br4923 WGARLRAFVVKKQDATIDEDAIKAYVRDHLARYKVPREVIFLEELPRNPT
:. : . :* :* *: . : ** .
MSMEG_2883|M.smegmatis_MC2_155 GKLLKRVLRERFARTTTDAI-----------------
Mvan_2882|M.vanbaalenii_PYR-1 GKLLKRSLREQFG-VDRGALS----------------
TH_2591|M.thermoresistible__bu GKLLKRVLRERYSEKAPH-------------------
Mflv_4559|M.gilvum_PYR-GCK GKLLKRELRERFASAMN--------------------
Mb0172|M.bovis_AF2122/97 GKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL
Rv0166|M.tuberculosis_H37Rv GKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL
MMAR_0409|M.marinum_M GKVLKTELRLRYGVGVYSESRSVSRSFEFREGS----
MAV_5018|M.avium_104 GKVLKTELRIRYGGG----------------------
MAB_4559|M.abscessus_ATCC_1997 GKILKRVLRQKY-----WESRDAGVS-----------
MUL_4126|M.ulcerans_Agy99 GKVVKPQLRELA-------------------------
MLBr_02546|M.leprae_Br4923 GKVLKRELRDFEVH-----------------------
**::* **