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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2319 | - | - | 100% (436) | S-(hydroxymethyl)glutathione dehydrogenase |
| M. thermoresistible (build 8) | TH_4349 | - | 3e-20 | 32.05% (234) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
| M. thermoresistible (build 8) | TH_2786 | - | 8e-18 | 31.74% (230) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1928 | - | 3e-16 | 43.16% (95) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1966 | - | 1e-87 | 66.53% (239) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv1895 | - | 7e-30 | 35.02% (217) | dehydrogenase |
| M. leprae Br4923 | MLBr_01784 | adhE2 | 4e-17 | 30.38% (237) | putative alcohol dehydrogenase (Zn dependent) |
| M. abscessus ATCC 19977 | MAB_2084 | - | 6e-17 | 30.77% (260) | zinc-type alcohol dehydrogenase AdhD |
| M. marinum M | MMAR_2790 | - | 2e-29 | 33.33% (237) | dehydrogenase |
| M. avium 104 | MAV_4101 | - | 1e-90 | 68.03% (244) | S-(hydroxymethyl)glutathione dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6616 | - | 4e-88 | 72.56% (215) | S-(hydroxymethyl)glutathione dehydrogenase |
| M. ulcerans Agy99 | MUL_2962 | - | 3e-30 | 31.76% (255) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4749 | - | 7e-90 | 68.57% (245) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1928|M.bovis_AF2122/97 MRAVVIDGAGSVRVNT---QPDPALP--GPDGVVVAVTAAGICGSDLHFY
Rv1895|M.tuberculosis_H37Rv MRAVVIDGAGSVRVNT---QPDPALP--GPDGVVVAVTAAGICGSDLHFY
MMAR_2790|M.marinum_M MRTVVIDGPGSIRVDN---RPDPALP--GSDGVIVAVSAAGICGSDLHFY
MUL_2962|M.ulcerans_Agy99 MRTVVIDGPGSIRVDN---RPDPALP--GSDGVIVVVSAAGICGSDLHFY
Mflv_1966|M.gilvum_PYR-GCK MKAVTWHGRRDVRVDT---VADPKIE--QPTDAIIEVTSTNICGSDLHLY
Mvan_4749|M.vanbaalenii_PYR-1 MRAVTWHGRRDVRVDS---VPDPKIE--EPTDAIIEVTSTNICGSDLHLY
MSMEG_6616|M.smegmatis_MC2_155 MKAVTWHGRRDVRVDN---VPDPKIE--QPTDAIIEVTSTNICGSDLHLY
MAV_4101|M.avium_104 MKAVTWHGKRDVRVDS---VPDPKIE--QPTDAIIEVTSTNICGSDLHLY
TH_2319|M.thermoresistible__bu ---VTWHGRRKVSVDT---VPDPAIM--EPTDAIIRVTSTNICGSDLHLY
MLBr_01784|M.leprae_Br4923 -MSQTVRGVISRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCHTDLTYR
MAB_2084|M.abscessus_ATCC_1997 ---MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLV
. : : : . .:: ::: .:* :*
Mb1928|M.bovis_AF2122/97 EGEYPFTEP-VALGHEAVGTIVEAGPQVRTVGVGDLVMVSSVAGCGVCPG
Rv1895|M.tuberculosis_H37Rv EGEYPFTEP-VALGHEAVGTIVEAGPQVRTVGVGDLVMVSSVAGCGVCPG
MMAR_2790|M.marinum_M EGEYPLAEP-VALGHEAVGTVVEKGPDVHTVEVGDQVMVSSVAGCGACAG
MUL_2962|M.ulcerans_Agy99 EGEYPLAEP-VALGHEAVGTVVEKGPDVHTVEVGDQVMVSSVAGCGACAG
Mflv_1966|M.gilvum_PYR-GCK EVLGAFMSEGDVLGHEPMGIVREVGAEVSNLSVGDRVVIPFQISCGHCFM
Mvan_4749|M.vanbaalenii_PYR-1 EVLGAFMNEGDILGHEPMGVVREVGSAVSNLAVGDRVVIPFQISCGHCFM
MSMEG_6616|M.smegmatis_MC2_155 EVLGAFMNEGDILGHEPMGIVREVGSAVDGLSVGDRVVIPFQISCGHCFM
MAV_4101|M.avium_104 EILGAFMKPGDILGHEPMGVVREVGTETGDLRVGDRVVIPFQICCGSCYM
TH_2319|M.thermoresistible__bu EVLSAFMSPGDILGHEAMGVVEEVGPEVGALQAGDRVVIPFNISCGTCWM
MLBr_01784|M.leprae_Br4923 EGGINDRYP-FLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAVCGQCRA
MAB_2084|M.abscessus_ATCC_1997 TGDLPIPLP-VVGGHEGAGTVVECGEGVEDLSEGDSVILTFLPSCGRCSY
*** * : * . : ** *:: ** *
Mb1928|M.bovis_AF2122/97 CE------------------PMIQSC-----------------------A
Rv1895|M.tuberculosis_H37Rv CETHDPVMCFS--------GPMIFGAGVLG------------GAQADLLA
MMAR_2790|M.marinum_M CATRDPAMCVS--------GPQIFGSGALG------------GAQADLLA
MUL_2962|M.ulcerans_Agy99 CATRDPAMCVS--------GPQIFGSGALG------------GAQADLLA
Mflv_1966|M.gilvum_PYR-GCK CDMKLYTQCETTQVREQGMGAALFGFSELYGSV--------PGGQAEYLR
Mvan_4749|M.vanbaalenii_PYR-1 CDRKLYTQCETTQVRDQGMGAALFGYSELYGSV--------PGGQAEYLR
MSMEG_6616|M.smegmatis_MC2_155 CDQKLYTQCETTQVREQGMGAALFGYSELYGSV--------PGGQAQYLR
MAV_4101|M.avium_104 CGQQLYTQCETTQVRDQGMGAALFGYSELYGEV--------PGGQAELLR
TH_2319|M.thermoresistible__bu CAQGLQSQCETTQNRDQGTGAALFGYSKLYGEV--------AGGQAEYLR
MLBr_01784|M.leprae_Br4923 CKRGRPSYCFDTFN-AQQKMTLIDGTELTPALG--------IGAFADKTL
MAB_2084|M.abscessus_ATCC_1997 CARGMGNLCELG--AALMMGPQIDGTYRFHARGEDVGQMCLLGTFSEYTV
* . : .
Mb1928|M.bovis_AF2122/97 SPAR----------------------------------------------
Rv1895|M.tuberculosis_H37Rv VPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGL
MMAR_2790|M.marinum_M VPAADFQVLKIPAAITTEQALLLTDNLATGWAAARRADILFGATVAVIGL
MUL_2962|M.ulcerans_Agy99 VPATDFQVLKIPAAITTEQALLLTDNLATGWAAARRADIPFGATVAVIGL
Mflv_1966|M.gilvum_PYR-GCK VPQAQFTHIKVPEGPDDSRFVYLSDVLPTAWQSVAYADIPDGGTVTVIGL
Mvan_4749|M.vanbaalenii_PYR-1 VPQAQFTHIKVPDGPPDSRFVYLSDVLPTAWQAVAYADVPDGGTVTVLGL
MSMEG_6616|M.smegmatis_MC2_155 VPQAQFTHIKVPDGPPDSRYVYLSDVLPTAWQSVAYAEIPKGGTVTVLGL
MAV_4101|M.avium_104 VPQAQFTHIKVPVGPPDSRFVYLSDVLPTAWQAVAYADIPDGGTVAVLGL
TH_2319|M.thermoresistible__bu VPQAQYTHITVPHDGPDDRYVYLSDVLPTAWQGVEYAAVPDGGTLVVLGL
MLBr_01784|M.leprae_Br4923 VHSGQCTKVD-PAADPAVAGLLGCGVMAGLGAAINTAAVSRDDTVAVIGC
MAB_2084|M.abscessus_ATCC_1997 VPQASVVKIDGGIPLDR-AALIGCGVTTGYGSAVRTGEVRAGDTVVVVGA
Mb1928|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv GAVGLCALRSAFIHGAATVFAVDRVKGRLQ-------RAATWGATPIPSP
MMAR_2790|M.marinum_M GAVGLCAVRSALAQGAATVFAVDRVQGRLQ-------RASEWGATAVASP
MUL_2962|M.ulcerans_Agy99 GAVGLCAVRSALAQGAATVFAVDRVQGRLQ-------RAAEWGATAVASP
Mflv_1966|M.gilvum_PYR-GCK GPIGDMAARIAQHKG-HTVFAVDFVPERLA--RAKARGIHTIDASALDGS
Mvan_4749|M.vanbaalenii_PYR-1 GPIGDMAARIAQHLG-YQVFAVDLVPERLD--RAIARGIHTIDASIVDGS
MSMEG_6616|M.smegmatis_MC2_155 GPIGDMAARIAHHLG-YEVFAVDRIPERLR--RAADRGIQAIDLGAIDEP
MAV_4101|M.avium_104 GPIGDMASRIADHLG-YRVIAVDLVPERLG--RAAQRGIHTIDLARLDAG
TH_2319|M.thermoresistible__bu GPIGSMACRIAAHRGNCRVIGVDRVPERIEKVRPYCADVLNVDTDDVEAA
MLBr_01784|M.leprae_Br4923 GGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFG---ATHTVNALELE
MAB_2084|M.abscessus_ATCC_1997 GGIGMNAIQGARIAGALAIVAVDPVNFKRE----QASGFGATHTAASMDE
Mb1928|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv AAETILAATRGRGADSVIDAVGTDAS------------------------
MMAR_2790|M.marinum_M AAEAIVAATGGRGADSVIDAVGTDAS------------------------
MUL_2962|M.ulcerans_Agy99 AAEAIVAATSGRGADSVIDAVDTDAS------------------------
Mflv_1966|M.gilvum_PYR-GCK VGDEVRRLTSGRGSDSVIDAVGMEAHGSPVAKAVQDATAFLPGAIAKP--
Mvan_4749|M.vanbaalenii_PYR-1 VGDEVRRLTGGRGSDSVIDAVGMEAHGSPVAKFAQQATALLPDAVAKP--
MSMEG_6616|M.smegmatis_MC2_155 LGDVIRSMTHGRGTDAVIDAVGMEAHGSPVAKIMQTAAAALPDAVAKP--
MAV_4101|M.avium_104 LGDAIRDLTDGRGADSVIDAVGMEAHGSPAAKLAQQVAGVLPDALGKR--
TH_2319|M.thermoresistible__bu VREQTGGXXVQTPPDPRRQSADCENHADQHGRPEHPPEELHHQADDQRQR
MLBr_01784|M.leprae_Br4923 VVKTIQDLTSGFGVDVVIDTVGRPET------------------------
MAB_2084|M.abscessus_ATCC_1997 AWSLVSDMTRGKLADVCILTTDVAEG------------------------
Mb1928|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv ----------------MSDALNAVRPGGTVSVVGVHD--LQPFPVPALTC
MMAR_2790|M.marinum_M ----------------MTDALNAVRAGGTVSVVGVHD--LQPFPLPALTC
MUL_2962|M.ulcerans_Agy99 ----------------MTDALNAVRAGGTVSVVGVHD--LQPFPLPALTC
Mflv_1966|M.gilvum_PYR-GCK ----MMKKAGVDRLDALYTAIDCVRRGGTLSVIGVYG--GMADPMPILTM
Mvan_4749|M.vanbaalenii_PYR-1 ----MMQKAGVDRLDALYTAIDCVRRGGTLSLIGVYG--GMADPMPMLTL
MSMEG_6616|M.smegmatis_MC2_155 ----MMENAGVDRLDALYSAIDTVRRGGTISLIGVYG--GTADPIPMLTL
MAV_4101|M.avium_104 ----LMQTAGVDRLSALYSAIDAVRRGGTISLIGVYG--GMADPLPMLTL
TH_2319|M.thermoresistible__bu RHERDAATAGSPPLPSPWPDRTTTHR-HTWRRLGGME--LLRDVVVLLHI
MLBr_01784|M.leprae_Br4923 ----------------WKQAFYARDLAGTVVLVGVPTP-DMRLDMPLLDF
MAB_2084|M.abscessus_ATCC_1997 --------------SYTAEALALVGKRGRVVVTAIGHPDESSISGSLLEM
Mb1928|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv LLRSITL---RMTMAPVQRTWPE-------LIPLLQ----------SGRL
MMAR_2790|M.marinum_M LLRSITL---RLTIAPVQRTWSE-------LIPLLE----------SGRL
MUL_2962|M.ulcerans_Agy99 LLRSITL---RLTIAPVQRTWSE-------LIPLLE----------SGRL
Mflv_1966|M.gilvum_PYR-GCK FDKQIQV---RMGQANVKRWVDD-------ILPLLT---------DEDPL
Mvan_4749|M.vanbaalenii_PYR-1 FDKQIQV---RMGQANVKKWVDD-------IMPLLT---------DSDPL
MSMEG_6616|M.smegmatis_MC2_155 FDKQIQL---RMGQANVKRWVDD-------IMPLLG---------DDDPL
MAV_4101|M.avium_104 FDKQVTL---RMGQANVKRWVDD-------IMPLLT---------DDDPL
TH_2319|M.thermoresistible__bu VGFAVTFGA-WTAEAVARRFRTTRLMDYGLLLSLITGLALAAPWPAGIVL
MLBr_01784|M.leprae_Br4923 FSHGGSLKSSWYGDCLPERDFPT-------LVDLYL----------QGRL
MAB_2084|M.abscessus_ATCC_1997 TLYEKQIRGALYGSSNAPHDIPR-------LVELYS----------AGLL
Mb1928|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv DVDGIFTTTLPLDEAAKGYATARARSGEELRFCLRPDSRDVLGAHETVDL
MMAR_2790|M.marinum_M DVDGIFTTSLPLDEAAKGYSIAGSRSGNDVKVLLKV--------------
MUL_2962|M.ulcerans_Agy99 DVDGIFTTSLPLDEAAKGYSIAGSRSGNDVKVLLKV--------------
Mflv_1966|M.gilvum_PYR-GCK GVDTFATHTLPLDQAPHAYEIFQKKQDGAVKVILKP--------------
Mvan_4749|M.vanbaalenii_PYR-1 GVDTFATHVLPMEEAPHAYKIFQQKQDGAVKVILQP--------------
MSMEG_6616|M.smegmatis_MC2_155 GVDDFATHILPIDEAPHAYEIFQKKQDGAVKIILKP--------------
MAV_4101|M.avium_104 GVDDFATHVLPLERAPHAYEIFQKKQDGAVKVILKP--------------
TH_2319|M.thermoresistible__bu NYPKIGLKLVLLVALGAVLGIGGAHQRRTGNPVPRPLFVTAGVLSFAAAA
MLBr_01784|M.leprae_Br4923 PLGKFVSERIGLGDVEEAFHKIHGGKVLRSVVML----------------
MAB_2084|M.abscessus_ATCC_1997 KLDELVTREYSLDQINEGYQDMRSGRNIRGLVRF----------------
Mb1928|M.bovis_AF2122/97 -----------------------------
Rv1895|M.tuberculosis_H37Rv YVHVRRCQSVADLQLEGAADGVDGPSMLN
MMAR_2790|M.marinum_M -----------------------------
MUL_2962|M.ulcerans_Agy99 -----------------------------
Mflv_1966|M.gilvum_PYR-GCK -----------------------------
Mvan_4749|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_6616|M.smegmatis_MC2_155 -----------------------------
MAV_4101|M.avium_104 -----------------------------
TH_2319|M.thermoresistible__bu VAVLW------------------------
MLBr_01784|M.leprae_Br4923 -----------------------------
MAB_2084|M.abscessus_ATCC_1997 -----------------------------