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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2025 | - | - | 100% (319) | enoyl-CoA hydratase, putative |
| M. thermoresistible (build 8) | TH_2728 | - | 2e-17 | 30.60% (232) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_1273 | - | 1e-13 | 27.24% (246) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0464c | echA2 | 5e-17 | 27.12% (306) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2422 | - | 1e-170 | 88.64% (317) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0456c | echA2 | 5e-17 | 27.12% (306) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 8e-06 | 37.35% (83) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3859c | - | 5e-17 | 23.10% (290) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4758 | echA4_1 | 1e-130 | 71.84% (316) | enoyl-CoA hydratase, EchA4_1 |
| M. avium 104 | MAV_2982 | - | 1e-104 | 58.01% (312) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_4852 | - | 1e-173 | 90.54% (317) | enoyl-CoA hydratase, putative |
| M. ulcerans Agy99 | MUL_0754 | echA4 | 2e-16 | 24.91% (289) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4230 | - | 1e-170 | 89.59% (317) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0464c|M.bovis_AF2122/97 --------------MPTPDFQTLLYTTAGPVATITLNRPEQLNTIVPPMP
Rv0456c|M.tuberculosis_H37Rv --------------MPTPDFQTLLYTTAGPVATITLNRPEQLNTIVPPMP
MAB_3859c|M.abscessus_ATCC_199 ---------------MVDTLKTMTYEVTDRVARITFNRPEQGNAIIADTP
MUL_0754|M.ulcerans_Agy99 -------MTHAIRPVDFDNLKTMTYEVTDRVARITFNRPEKGNAIVADTP
Mflv_2422|M.gilvum_PYR-GCK --MAERPSPSAAERPTPEEIILYEKDPQTKIATITFNRPEFLNAPTSMAR
Mvan_4230|M.vanbaalenii_PYR-1 --MAERPQPPAAERPAPEEIILYDKDPKTKIATITFNRPEFLNAPTSMAR
MSMEG_4852|M.smegmatis_MC2_155 ----------MAERPTPEEIILYDKDPETKIATITFNRPEFLNAPTSMAR
TH_2025|M.thermoresistible__bu ----------MADRPAPEEIILYDKDPRTKIATITFNRPEFLNAPTSAAR
MMAR_4758|M.marinum_M ---------MPKSEPPVDKVIRYDKDPETRIATITFDRPGHLNAPTIAAR
MAV_2982|M.avium_104 ----MPEYDYEELKKEAEQYIKFEKDKKNRIAYITFDRPDAQNSATLGMR
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
:* **::** *:
Mb0464c|M.bovis_AF2122/97 DEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHWG--------
Rv0456c|M.tuberculosis_H37Rv DEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHWG--------
MAB_3859c|M.abscessus_ATCC_199 LELAALVERADLDPQVHVILVSGRGDGFCGGFDLSAYAEANDEGSVR--Y
MUL_0754|M.ulcerans_Agy99 LELSALVERADLDPAVQVILVSGRGEGFCAGFDLSAYAEGSSSSGAEGGY
Mflv_2422|M.gilvum_PYR-GCK LRYADVLRAANADNDVKVVIIRGVGDNLGSGADLPEFMEGNDNP--AVRL
Mvan_4230|M.vanbaalenii_PYR-1 LRYADVLRAANTDNDVKVVIIRGVGDNLGSGADLPEFMEGNDNP--AARL
MSMEG_4852|M.smegmatis_MC2_155 LRYADVLRAANADNDVKVVVIRGVGDNLGSGADLPEFMEGNDNP--AVRL
TH_2025|M.thermoresistible__bu LRYADLLRAATVDNDVKVVVIRGVGDNLGSGADLPEFMEGNDNP--ALRL
MMAR_4758|M.marinum_M LRYADLLHRASIDDEVKVLVIRGEGEDLGSGADLEEFMEVMNSPDQGPRL
MAV_2982|M.avium_104 QNYADLIHKCNVDDDVKVVVIRGEGEDFGSGGDLPEQRGMLENPG-MPLL
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQK---------------
: * ::*::: * * : .* *
Mb0464c|M.bovis_AF2122/97 -----------DAMMTDGRWDPGKDFAMVTARETGPTQKFMAIWRASKPV
Rv0456c|M.tuberculosis_H37Rv -----------DAMMTDGRWDPGKDFAMVTARETGPTQKFMAIWRASKPV
MAB_3859c|M.abscessus_ATCC_199 SGTALDGQVQLRNHLPNINWDPMLDYQMMSRFTRG----FSSLLHANKPT
MUL_0754|M.ulcerans_Agy99 RGTVLDGKAQAVNHLPNQPWDPMIDYQMMSRFVRG----FSSLTHADKPT
Mflv_2422|M.gilvum_PYR-GCK AELRLEDDGVGEVTYPPK--GTFRNGATISAWYANSQAGNRALQDFKKIS
Mvan_4230|M.vanbaalenii_PYR-1 AELRLEDDGVGEVTYPPK--GTFRNGATISAWYANSQAGNRALQDFKKIS
MSMEG_4852|M.smegmatis_MC2_155 AELRLEDDGVGEVTYPPR--GTFRNGATISAWYANSQAGNRALQDFKKIS
TH_2025|M.thermoresistible__bu AELRLEDDGVGEVTYPPK--GTFRNGATISAWYANSQAGNRPLQELKKIS
MMAR_4758|M.marinum_M AEFRIGPE---EVKYPPL--GSFRHGASVSQWYANPNAGIRGLQDFKKIS
MAV_2982|M.avium_104 HELAINDD---DVKYPPG--GSYRYLSTVTDFYAKARAGNRPLQELRKIS
MLBr_01241|M.leprae_Br4923 ------------FTAPVPQVEGLTQPVRALRAMELLEEVILALRRLHQPV
. : :
Mb0464c|M.bovis_AF2122/97 IAQVHGWCVGGASDYALCADIVIASEDAVIGTPYSR---MWG-AYLTGMW
Rv0456c|M.tuberculosis_H37Rv IAQVHGWCVGGASDYALCADIVIASEDAVIGTPYSR---MWG-AYLTGMW
MAB_3859c|M.abscessus_ATCC_199 VVKVHGYCVAGGTDIALHADQLIVAADAKIGYPPTR---VWG-VPATGLW
MUL_0754|M.ulcerans_Agy99 VVKIHGYCVAGGTDIALHADQVIAAADAKIGYPPTR---VWG-VPAAGLW
Mflv_2422|M.gilvum_PYR-GCK IVEAKGYCYGWHFYQCADADLVISSDDALFGHPSFR---YHGWGPRMWTW
Mvan_4230|M.vanbaalenii_PYR-1 IVEAKGYCYGWHFYQCADADLVISSDDALFGHPSFR---YHGWGPRMWTW
MSMEG_4852|M.smegmatis_MC2_155 IVEAKGYCYGWHFYQCADADLVISSDDALFGHPSFR---YHGWGPRMWTW
TH_2025|M.thermoresistible__bu IVEAKGYCYGWHFYQCADADLVISSDDALFGHPSFR---YYGWGPRMWTW
MMAR_4758|M.marinum_M ILEVKGYCYGWHFYQAADADLVISSDDALFGHPSFR---YYGWGPRMWWW
MAV_2982|M.avium_104 IIEAKGYCYGWHFYQAGDADLVIASDDALFGHPAFR---YVGWGPRLWWW
MLBr_01241|M.leprae_Br4923 IAAINGPAIGGGLCLALAADVRVASTRAYFRAAGINNGLSASELGLSYLL
: :* . . . ** : : * : . . .
Mb0464c|M.bovis_AF2122/97 LYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEIATEL
Rv0456c|M.tuberculosis_H37Rv LYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEIATEL
MAB_3859c|M.abscessus_ATCC_199 AHKLGDQRAKRLLLTGDCLSGRQAYDWGLAVEAPEPDELDERTERLVERI
MUL_0754|M.ulcerans_Agy99 AHRLGDQRAKRLLFTGDCITGAQAAEWGLAVEAPDPKDLDERTERLVERI
Mflv_2422|M.gilvum_PYR-GCK VQMMGLRKFQEMVFTGRPFTAAEMYDCNFLNKVVERDQLEAETQKYALAC
Mvan_4230|M.vanbaalenii_PYR-1 VQMMGLRKFQEMVFTGRPFTAAEMYDCNFLNKVVTRDQLEAETRKYALAC
MSMEG_4852|M.smegmatis_MC2_155 VQMMGLRKFQEMVFTGRPFTAAEMYDCNFLNKVVPRDRLEAEVDKYATAC
TH_2025|M.thermoresistible__bu VQMMGLRKFSEMVFTGRPFTAAEMYDCNFLNKVVPRDQLEAEVDKYARAC
MMAR_4758|M.marinum_M AQTMGIRKFQEMVFTGRAFTAAEMQDCNFLNSVVPREELEAEVAKYALAC
MAV_2982|M.avium_104 AETMGLRKFSEMLFTGRPFSAKEMYDCGFVNSVVPRDKLEAETEKYALAC
MLBr_01241|M.leprae_Br4923 PRAVGSSRAFEIMLSGRDVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARM
:. : ::* . . : : : . * .
Mb0464c|M.bovis_AF2122/97 AR-IPLSQLQAQKLIVNQAYENMGLASTQLLGGILDGLMR---NTPDALE
Rv0456c|M.tuberculosis_H37Rv AR-IPLSQLQAQKLIVNQAYENMGLASTQLLGGILDGLMR---NTPDALE
MAB_3859c|M.abscessus_ATCC_199 AA-MPLNQLMMIKLACNSVLINQGIANSAMIGTVFDGISR---HTPEAHA
MUL_0754|M.ulcerans_Agy99 AA-LPVNQLIMIKLALNSALLQQGGVNSRMLSTVFDGVAR---HTPEGHA
Mflv_2422|M.gilvum_PYR-GCK ARNRPVDTVFQQKMFFEIFKQQQGEYMGSLLSAFFESMGNGVANDSDEDL
Mvan_4230|M.vanbaalenii_PYR-1 ARNRPVDTVFQQKMFFEIFKQQQGEYMGSLLSAFFESMGNGVANDSDDDL
MSMEG_4852|M.smegmatis_MC2_155 ARNRPVDTVFQQKMFFEIFKQQQGEYMGSLLSAFFESMGNGVANDSDDDL
TH_2025|M.thermoresistible__bu ARNRPVDTVFQQKIFFEVFKQHQGEYMGSLLSAFFESMGSGAVNDDTDDL
MMAR_4758|M.marinum_M ARNRPNDTVFMQKVFFEIMKQFQGEYMGSLLSGFFESMGSGVRADT-DDL
MAV_2982|M.avium_104 SKARPTDTVAVQKTFLELYKQHKGEYFGSLLTGLVEGMLPLIANDAEEVD
MLBr_01241|M.leprae_Br4923 ATFSRSGTELTKRALWG-----------GLDAASLDKHMQSESLAQLFIA
: . : : .:
Mb0464c|M.bovis_AF2122/97 FIRTAQTQGVRAAVERRDGPFGDYSQAPPELRPDPTHVITPDGSM---
Rv0456c|M.tuberculosis_H37Rv FIRTAQTQGVRAAVERRDGPFGDYSQAPPELRPDPTHVITPDGSM---
MAB_3859c|M.abscessus_ATCC_199 FTADAIANGYRQAVRHRDEPFGDYGRKPTEL-----------------
MUL_0754|M.ulcerans_Agy99 FVADAVEHGFRDAVNHRDEPFGDYGRRASSV-----------------
Mflv_2422|M.gilvum_PYR-GCK DMFESIDSGLSAAVNDNDSKFPPEFRLSKRNRAKD-------------
Mvan_4230|M.vanbaalenii_PYR-1 DMFESIDSGLSAAVNDNDSKFPPEFRLSKRNRAKKD------------
MSMEG_4852|M.smegmatis_MC2_155 DMFESIDSGLSAAVNDNDSRFPPEFRLSKKNRAKP-------------
TH_2025|M.thermoresistible__bu DMHEAIDSGLADAVNDNDMRFPPEFRLSKSNRAKE-------------
MMAR_4758|M.marinum_M MLDDAIEQGLGDAVKDNDSRFPPEWRLSKKSRAKDGTGKPAKQKKKKG
MAV_2982|M.avium_104 LTAGTFEKGLNNVVKDNDLNFPPEWRLSRSGRAKP-------------
MLBr_01241|M.leprae_Br4923 LHTSNFEEAAAPCTEKRPTVLVDARGCATSPG----------------
. .. . : .