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M. thermoresistible (build 8) TH_2728 (-)

annotation: Enoyl-CoA hydratase/isomerase
coordinates: 3953187 - 3953969
length: 261

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2728--100% (261)Enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8)TH_2027echA132e-5042.42% (264) POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE)
M. thermoresistible (build 8)TH_1770echA132e-4843.32% (247) POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1970cechA134e-5244.70% (264) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2433-1e-14091.15% (260) enoyl-CoA hydratase
M. tuberculosis H37RvRv1935cechA135e-5244.70% (264) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-2e-2735.94% (217) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_2058-2e-2738.03% (234) enoyl-CoA dehydratase/isomerase
M. marinum MMMAR_4972echA13_12e-5244.57% (258) enoyl-CoA hydratase EchA13_1
M. avium 104MAV_0670-5e-5242.86% (280) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_4846-1e-13587.69% (260) enoyl-CoA hydratase
M. ulcerans Agy99MUL_0210echA87e-2936.15% (213) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4219-1e-14191.92% (260) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1970c|M.bovis_AF2122/97           MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
Rv1935c|M.tuberculosis_H37Rv        MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_4972|M.marinum_M               ------MTLSEQADTSAEGVA-PAELVAYETLDEGRIARIWLNRPEAHNA
MAV_0670|M.avium_104                ------MTLSEQAGAQPGARP-AEELVTYETLDEGRIARIWLNRPDAHNA
Mflv_2433|M.gilvum_PYR-GCK          ------------------------MYIDYEVSD--RIATITLNRPEAANA
Mvan_4219|M.vanbaalenii_PYR-1       ------------------------MYIDYDVTD--RIATITLNRPEAANA
TH_2728|M.thermoresistible__bu      ------------------------MYIDYDVSD--RIATITLNRPEAANA
MSMEG_4846|M.smegmatis_MC2_155      ------------------------MYIDYGVAD--SIATITLNRPEAANA
MLBr_02402|M.leprae_Br4923          ---------------------MKYDTILVDGYQ--RVGIITLNRPQALNA
MUL_0210|M.ulcerans_Agy99           ---------------------MSYETILVERDQ--RVGIITLNRPQALNA
MAB_2058|M.abscessus_ATCC_1997      ---------------------MAEQPIRYEVVD--SVAWLTINRPEARNA
                                                              :     :   :. : ::**.  **

Mb1970c|M.bovis_AF2122/97           QTRGMLVELGAAFELAEADDTVRVVILRAA-GPAFSAGHDLGSADDIRER
Rv1935c|M.tuberculosis_H37Rv        QTRGMLVELGAAFELAEADDTVRVVILRAA-GPAFSAGHDLGSADDIRER
MMAR_4972|M.marinum_M               QNRTLLVQLDEAFGRAEADDTVRVVILAAR-GKNFSAGHDLGSEAALLER
MAV_0670|M.avium_104                QSRGLLVQLDEAFVRAEADDAVRVVILAAR-GKNFSAGHDLGSELALAER
Mflv_2433|M.gilvum_PYR-GCK          QNPELLDELDAAWTRAAEDNDVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
Mvan_4219|M.vanbaalenii_PYR-1       QNPELLDELDAAWTRAAEDNEVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
TH_2728|M.thermoresistible__bu      QNPELLDELDAAWTRAAEDNDVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
MSMEG_4846|M.smegmatis_MC2_155      QNPELLDELDAAWTRAAEDNEVKVIILRAN-GKHFSAGHDLRGGGEVPEK
MLBr_02402|M.leprae_Br4923          LNSQMMNEITNAAKELDIDPDVGAILITGS-PKVFAAGADIKEMASLTFT
MUL_0210|M.ulcerans_Agy99           LNSQVMNEVTSAAAELDNDPGIGAIIITGS-AKAFAAGADIKEMADLTFS
MAB_2058|M.abscessus_ATCC_1997      LNNAVRTGLIDAVLRFNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQNALK
                                     .  :   :  *      *    .::: .     *.** *:         

Mb1970c|M.bovis_AF2122/97           SPGPDQHPSYRCNGATFGGVESR-NRQEWHYYFENTKRWRNLRKITIAQV
Rv1935c|M.tuberculosis_H37Rv        SPGPDQHPSYRCNGATFGGVESR-NRQEWHYYFENTKRWRNLRKITIAQV
MMAR_4972|M.marinum_M               KPGPAQHPTFRSHGGTRDAVMEKLYLQEWHFYFQNTCRWRDLRKITIAQV
MAV_0670|M.avium_104                QPGPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQV
Mflv_2433|M.gilvum_PYR-GCK          IT------------------LEFIIQHEAKRYLEYTLRWRNVPKPSIAAV
Mvan_4219|M.vanbaalenii_PYR-1       IT------------------LEFIIAHEAKRYLEYTLRWRNVPKPSIAAV
TH_2728|M.thermoresistible__bu      LT------------------LEFIYAHESRRYLEYSLRWRNVPKPSIAAV
MSMEG_4846|M.smegmatis_MC2_155      IS------------------LEFIIQHEARRYLDYTLRWRNVPKPSIAAV
MLBr_02402|M.leprae_Br4923          DAFD-------------------------ADFFSAWGKLAAVRTPMIAAV
MUL_0210|M.ulcerans_Agy99           EAFD-------------------------ADFFAAWGKLAAVRTPTIAAV
MAB_2058|M.abscessus_ATCC_1997      VPP--------------------------KDFAPQFGRNIDVAKPTIAAV
                                     .                             :     :   : .  ** *

Mb1970c|M.bovis_AF2122/97           HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFG-HPWEFG
Rv1935c|M.tuberculosis_H37Rv        HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFG-HPWEFG
MMAR_4972|M.marinum_M               QGNAISAALMLIWACDLIVAADNAKFSDVVAVRLGMPGVEYYA-HPWEFG
MAV_0670|M.avium_104                QGNAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPGVEYYA-HPWEFG
Mflv_2433|M.gilvum_PYR-GCK          QGRCISGGLLLCWPCDLIVAADDAQFSDPV-VLMGIGGVEYHG-HTWELG
Mvan_4219|M.vanbaalenii_PYR-1       QGRCISGGLLLCWPCDLIVAADDAQFSDPV-VLMGIGGVEYHG-HTWELG
TH_2728|M.thermoresistible__bu      QGRCISGGLLLCWPCDLIIAAEDALFSDPV-VLMGIGGVEYHG-HTWELG
MSMEG_4846|M.smegmatis_MC2_155      QGRCISGGLLLCWPCDLILASDDALFSDPV-ALMGIGGVEYHG-HTWELG
MLBr_02402|M.leprae_Br4923          AGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIG
MUL_0210|M.ulcerans_Agy99           AGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIG
MAB_2058|M.abscessus_ATCC_1997      NGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG--RGSPWATPLSWLVP
                                     *  :...  :   ***::*:: : *.          *       .  . 

Mb1970c|M.bovis_AF2122/97           PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
Rv1935c|M.tuberculosis_H37Rv        PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
MMAR_4972|M.marinum_M               PRKAKELLLTGDSLDAEEAYRLGMVSKVFPADELADKTLQFARRIAERPT
MAV_0670|M.avium_104                PRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAERPT
Mflv_2433|M.gilvum_PYR-GCK          PRKAKEILFTGRAMTADEVAATGMVNKVVPRAELDAETRALAEQIAKMPP
Mvan_4219|M.vanbaalenii_PYR-1       PRKAKEILFTGRAMTAEEVAATGMVNRVVPRDQLDAETRTLAEQIAKMPP
TH_2728|M.thermoresistible__bu      PRKAKEILFTGRAMTAEEVAQTGMVNRVVPRDRLDAETRALAGEIAKMPP
MSMEG_4846|M.smegmatis_MC2_155      PRKAKEILFTGRALTAEEAERTGMVNRVVARDELDAQTRELAEQIATMPP
MLBr_02402|M.leprae_Br4923          KAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSR
MUL_0210|M.ulcerans_Agy99           KAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVATTISQMSR
MAB_2058|M.abscessus_ATCC_1997      PRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRERTQQLALSIAANAP
                                       : ::::**  : * ..   *:*..*.    *   :  .*  *:  . 

Mb1970c|M.bovis_AF2122/97           MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
Rv1935c|M.tuberculosis_H37Rv        MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
MMAR_4972|M.marinum_M               MAALLVKDSVNAASDAMGFTEALRHAFHVHELGHAHWAAHNENRYPIG-L
MAV_0670|M.avium_104                MAALLIKDSVNAASDAMGFTEALRHAFHIHELGHAHWAAHNENRYPVG-L
Mflv_2433|M.gilvum_PYR-GCK          FALRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGG-----WPV
Mvan_4219|M.vanbaalenii_PYR-1       FALRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGG-----WPV
TH_2728|M.thermoresistible__bu      FALRQAKRAVNQTLDVQGFYAAIQSVFDIHQTGHGNAMSVSG-----WPV
MSMEG_4846|M.smegmatis_MC2_155      FALRQAKRAVNQTLDVQGFYAAIQSVFDIHQTGHGNALSVSG-----WPV
MLBr_02402|M.leprae_Br4923          SATRMAKEAVNRSFEST-LAEGLLHERRLFHSTFVTDDQSEG--------
MUL_0210|M.ulcerans_Agy99           SAARMAKEAVNRTFEAT-LAEGLLYERRLIHSAFATADQSEG--------
MAB_2058|M.abscessus_ATCC_1997      LSVLASKRTVYLSAQHH-LAAAYDLADEIWEPVYLSDDAQEG--------
                                     :    * :*  : :   :  .      : .  .                

Mb1970c|M.bovis_AF2122/97           EYGLEDWRAAPQIRPAIKQRP
Rv1935c|M.tuberculosis_H37Rv        EYGLEDWRAAPQIRPAIKQRP
MMAR_4972|M.marinum_M               PPDVEDWRTAGPTQVARRDTP
MAV_0670|M.avium_104                PPDVEDWRNAKPTRLARRDTP
Mflv_2433|M.gilvum_PYR-GCK          LVNLEEMKANIK---------
Mvan_4219|M.vanbaalenii_PYR-1       LVNLEEMKANIK---------
TH_2728|M.thermoresistible__bu      LVDIEEMKANIK---------
MSMEG_4846|M.smegmatis_MC2_155      LVDIEEMKANIK---------
MLBr_02402|M.leprae_Br4923          MAAFIEKRAPQFTHR------
MUL_0210|M.ulcerans_Agy99           MAAFIEKRPPNFTHR------
MAB_2058|M.abscessus_ATCC_1997      PAAFREKRAPQWKGH------
                                       . : :