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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1879 | fadD9 | - | 100% (595) | PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) |
M. thermoresistible (build 8) | TH_3730 | - | 6e-40 | 41.44% (292) | PUTATIVE linear gramicidin synthetase subunit D |
M. thermoresistible (build 8) | TH_3141 | - | 2e-28 | 50.00% (122) | PUTATIVE amino acid adenylation domain |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 0.0 | 65.82% (591) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_2696 | - | 6e-30 | 42.86% (154) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv0101 | nrp | 0.0 | 65.82% (591) | peptide synthetase |
M. leprae Br4923 | MLBr_00484 | fadD9 | 1e-160 | 55.31% (537) | putative acyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_4098c | - | 0.0 | 68.35% (594) | peptide synthetase NRP |
M. marinum M | MMAR_2117 | fadD9 | 1e-163 | 56.24% (553) | fatty-acid-CoA ligase FadD9 |
M. avium 104 | MAV_3243 | - | 0.0 | 67.40% (589) | linear gramicidin synthetase subunit B |
M. smegmatis MC2 155 | MSMEG_0402 | - | 0.0 | 77.04% (588) | linear gramicidin synthetase subunit D |
M. ulcerans Agy99 | MUL_1722 | - | 1e-162 | 56.24% (553) | fatty-acid-CoA ligase FadD9 |
M. vanbaalenii PYR-1 | Mvan_2578 | - | 1e-166 | 58.80% (517) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0104|M.bovis_AF2122/97 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATV Rv0101|M.tuberculosis_H37Rv MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATV MAB_4098c|M.abscessus_ATCC_199 ----------MSADPT-RTLLSMDLLDDDDHDRLDEWGNRAVLTEPAAEP MAV_3243|M.avium_104 ----------MTVGAG-RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAP MSMEG_0402|M.smegmatis_MC2_155 ----------MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTP TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -----------------------MTDTDLDARRLELLRRRLAGSGLREQD Mb0104|M.bovis_AF2122/97 LDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGK Rv0101|M.tuberculosis_H37Rv LDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGK MAB_4098c|M.abscessus_ATCC_199 VSIPVVFAVQVERAPETVALVCRDRSWTYRELDQITNRIAHLLAGNGAGP MAV_3243|M.avium_104 ASIPGMFAAQVARSAEAVALSFEGRSMTYRELDEASNRLAHLLAEQGAAP MSMEG_0402|M.smegmatis_MC2_155 VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKP TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK PAEPVAVAADPARG----EFTDGQKRMWFVHSVDPSGVLLNVCLSYRISG Mb0104|M.bovis_AF2122/97 PLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGE Rv0101|M.tuberculosis_H37Rv PLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGE MAB_4098c|M.abscessus_ATCC_199 GEVVGLLVPRSGEAIIGLLAILKTGAAYLPIDPAHPDERIKFMVSDAG-- MAV_3243|M.avium_104 GECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPAARMEFMLGDAT-- MSMEG_0402|M.smegmatis_MC2_155 GATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAK-- TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK EVDLARLHDAVTAVARRHPVLRTTFAADEAGEPQRTVHDDLLPG------ Mb0104|M.bovis_AF2122/97 TPSVGAGLAKLREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSV Rv0101|M.tuberculosis_H37Rv TPSVGAGLAKLREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSV MAB_4098c|M.abscessus_ATCC_199 -PVAVLTTADLGSRFEGLDVSVIEIDDPLID---GQPSSALPTPEPDDLA MAV_3243|M.avium_104 -PIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA MSMEG_0402|M.smegmatis_MC2_155 -PVAALTTADLRSRLDQYDLAVIDMADPAID---RRPSDALSGPRPDDLA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK --WTVQDISELSEHARRLRLEVLAQREFGTPFDLATESPLRITVARTAPA Mb0104|M.bovis_AF2122/97 SDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVLVAAAAVAVDA Rv0101|M.tuberculosis_H37Rv SDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVLVAAAAVAVDA MAB_4098c|M.abscessus_ATCC_199 YMTYTSGTTGVPKAVAVTHHNVTQLVDAVRADLPARPGEVWSQWHSLVFD MAV_3243|M.avium_104 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFD MSMEG_0402|M.smegmatis_MC2_155 YMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFD TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK EYIMLLVVHHIAWDDGCWRVFFADLTRAYTGAELGPTPAPVVEPPTSDED Mb0104|M.bovis_AF2122/97 SLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Rv0101|M.tuberculosis_H37Rv SLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR MAB_4098c|M.abscessus_ATCC_199 VSVWEIWGALLHGGRLVVVPESVASSPDDLHELLISEKVSVLCQTPSAAG MAV_3243|M.avium_104 VSVWETWGALLHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVG MSMEG_0402|M.smegmatis_MC2_155 VSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M ------------------------MSPITREER-LERRIQDLYANDPQFA MUL_1722|M.ulcerans_Agy99 ------------------------MSPITREER-LERRIQDLYANDPQFA MLBr_00484|M.leprae_Br4923 ----------MWRQQSISHRKESVMSTITKQEKQLARRVDDLTANDPQFA Mvan_2578|M.vanbaalenii_PYR-1 ------------------------MSTDTREDR-LARRIADLYATDPQFA Mflv_2696|M.gilvum_PYR-GCK LRFWRSAMTDLPEPLELPGPHG-SAVPTTWRCRRVTATLSADTVERVRVA Mb0104|M.bovis_AF2122/97 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLR Rv0101|M.tuberculosis_H37Rv TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLR MAB_4098c|M.abscessus_ATCC_199 MLSPERLESTTLIVAGEACPPELVDRWATSGRTMINAYGPTEATIYAAMS MAV_3243|M.avium_104 MLSPEGLDSTALVVAGEACPAEVVDRWAP-GRVMINAYGPTEATVYAAMS MSMEG_0402|M.smegmatis_MC2_155 MLSPEGLESTTLIVAGEACPTELVDRWAP-GRVMINAYGPTEATIYAAMS TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M AAKPA-------------------------------------TAITAAIE MUL_1722|M.ulcerans_Agy99 AAKPV-------------------------------------TAITAAIE MLBr_00484|M.leprae_Br4923 AAKPD-------------------------------------PAVAAALA Mvan_2578|M.vanbaalenii_PYR-1 AAAPD-------------------------------------DAISHAID Mflv_2696|M.gilvum_PYR-GCK AREAG-------------------------------------ATPYMVML Mb0104|M.bovis_AF2122/97 PFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHP-- Rv0101|M.tuberculosis_H37Rv PFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHP-- MAB_4098c|M.abscessus_ATCC_199 GPLTPGSGVAPIGSPVPGAALFVLDKWLRPAPEGVVGELYVAGNGVAPGY MAV_3243|M.avium_104 APLTAESGAPPIGSPVPGAALFVLDKWLRPAPEGVVGELYIAGRGVATGY MSMEG_0402|M.smegmatis_MC2_155 EPLTAGTGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGY TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M RP----------GLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTG--- MUL_1722|M.ulcerans_Agy99 RP----------GLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTG--- MLBr_00484|M.leprae_Br4923 QP----------GLRLPQIIQTALDGYAERPALGQRVAEFTKDPKTG--- Mvan_2578|M.vanbaalenii_PYR-1 QP----------GTHLPVIVQTVLDGYAERPALGQRAVRFVTDPATG--- Mflv_2696|M.gilvum_PYR-GCK AAFGALLHRYTHADDVLIASPVLLRGPDSEDVIGYHGNSAVMRLRPQPMQ Mb0104|M.bovis_AF2122/97 -KVAERIAA-ALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPS Rv0101|M.tuberculosis_H37Rv -KVAERIAA-ALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPS MAB_4098c|M.abscessus_ATCC_199 AHRSGLTAS-RFLACPFGGPGSRMYRTGDLVQWGEDGQLQYLGRADEQVK MAV_3243|M.avium_104 ARRAGLTAS-RFVACPFGGPGARMYRTGDLVRWGADGQLQYLGRADEQVK MSMEG_0402|M.smegmatis_MC2_155 IGRPDLTAS-RFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVK TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -HTTLRLLP-HFETISYGELWDRISALADVLST------EQTVKPGDRVC MUL_1722|M.ulcerans_Agy99 -HTTLRLLP-HFETISYGELWDRISALADVLST------EQTVKPSDRVC MLBr_00484|M.leprae_Br4923 -RTSMELLP-SFETITYRQLGDRVGALARAWR-------HDLLHAGYRVC Mvan_2578|M.vanbaalenii_PYR-1 -RTTTELLP-RFETITYAELSRRIHAVTAALT---------DVHPGDRVA Mflv_2696|M.gilvum_PYR-GCK TFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDRRHGAERMTRVSFGFR Mb0104|M.bovis_AF2122/97 TPAWFLDSARGVHQFLGRRRFVYPWVAWL-------------VQRGAAPG Rv0101|M.tuberculosis_H37Rv TPAWFLDSARGVHQFLGRRRFVYPWVAWL-------------VQRGAAPG MAB_4098c|M.abscessus_ATCC_199 IRGYR-IELGEIQAALSRLDGVEQAVVIAREDRPGDKRLVGYIMGTADPV MAV_3243|M.avium_104 IRGYR-IELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTADPA MSMEG_0402|M.smegmatis_MC2_155 IRGYR-IELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M LLGFNSVDYATIDMTLARLG----AVAVP-------------LQTSAAIT MUL_1722|M.ulcerans_Agy99 LLGFNSVDYATIDMTLARLG----AVAVP-------------LQTSAAIT MLBr_00484|M.leprae_Br4923 VLGFNSVDYAIIDMALGVIG----AVAVP-------------LQTSAAIT Mvan_2578|M.vanbaalenii_PYR-1 VLGFTSIDYTTVDMALAMLG----AVAVP-------------LQTSAPAT Mflv_2696|M.gilvum_PYR-GCK EPDGGGFSPPGVTCRRAELRGQITQLPLG-------------LMVELHES Mb0104|M.bovis_AF2122/97 DVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGI Rv0101|M.tuberculosis_H37Rv DVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGI MAB_4098c|M.abscessus_ATCC_199 EARNALAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRSVGTDY MAV_3243|M.avium_104 ELRTQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQY MSMEG_0402|M.smegmatis_MC2_155 QLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDY TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M QLQPIVAETQPTMIAASVDALADATELALSGQTATRVLVFDHHRQVDAHR MUL_1722|M.ulcerans_Agy99 QLQPIVAETQPTMIAASVDALADATELALSGQTATRVLVFDHHRQVDAHR MLBr_00484|M.leprae_Br4923 QLQSIVTETEPSMIATSVNQLPDTVELILSGQAPAKLVVFDYHPEVDEQH Mvan_2578|M.vanbaalenii_PYR-1 TVRPIVAETEPVVIASSVDALTDAVGLALDAPTVTRLVVFDHRAGVDDHR Mflv_2696|M.gilvum_PYR-GCK GAVVEAEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELMDGDD Mb0104|M.bovis_AF2122/97 LVTVVD-------------------------------------VAATQLA Rv0101|M.tuberculosis_H37Rv LVTVVD-------------------------------------VAATQLA MAB_4098c|M.abscessus_ATCC_199 RAPSGPVEKVLADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVSRARAA MAV_3243|M.avium_104 RAPSNHTEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA MSMEG_0402|M.smegmatis_MC2_155 RAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M AAVES---------------------------------------ARERLA MUL_1722|M.ulcerans_Agy99 AAVES---------------------------------------ARERLA MLBr_00484|M.leprae_Br4923 DAVAT---------------------------------------ARARLA Mvan_2578|M.vanbaalenii_PYR-1 DALIS---------------------------------------ASDRLR Mflv_2696|M.gilvum_PYR-GCK AEWLRR-------------------------------------VSHGPEF Mb0104|M.bovis_AF2122/97 VVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG-------------- Rv0101|M.tuberculosis_H37Rv VVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG-------------- MAB_4098c|M.abscessus_ATCC_199 GVHCRPRDIFVEQTVSGVAAVASLSDGRAGIVDDGIGPVLATPIIHWLQG MAV_3243|M.avium_104 GVICRPRDVFVEQTVARLARVASDGADEEQVVDEGIGPVQATPIMRWLQT MSMEG_0402|M.smegmatis_MC2_155 GIQCRPRDIFVEQTVAGVARVAVAAG-ESHVVDEGVGPVVATPIMRWLRE TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M G------SAVVETLAEAIARGDVPRGASAGSAPGTD-------------- MUL_1722|M.ulcerans_Agy99 G------SAVVETLAEAIARGDVPRGASAGSAPGTD-------------- MLBr_00484|M.leprae_Br4923 DS-----SVVVESLTEVLGRGKTLP---ATPIPVAD-------------- Mvan_2578|M.vanbaalenii_PYR-1 AANS---PIEVETITDIVARGSKLP-----VRAQFS-------------- Mflv_2696|M.gilvum_PYR-GCK DVPAATIGELIEARTDLTPDTVAVVYEGRRYTYREIN------------- Mb0104|M.bovis_AF2122/97 ----------------------------------------TTGQPKLVRI Rv0101|M.tuberculosis_H37Rv ----------------------------------------TTGQPKLVRI MAB_4098c|M.abscessus_ATCC_199 VPGPVDQFNQTIVLQAPVGVTEDDVVVILQALLDRHATLRLRAESG-DAS MAV_3243|M.avium_104 VQGPIDDFNQTMVLAAPSGVTADDVAVVLQALLDRHPMLRLRVED--DGA MSMEG_0402|M.smegmatis_MC2_155 VDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDT TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -----------------------------------------------VSD MUL_1722|M.ulcerans_Agy99 -----------------------------------------------VSD MLBr_00484|M.leprae_Br4923 -----------------------------------------------DSA Mvan_2578|M.vanbaalenii_PYR-1 -----------------------------------------------ADG Mflv_2696|M.gilvum_PYR-GCK -----------------------------------------------ESA Mb0104|M.bovis_AF2122/97 SHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV Rv0101|M.tuberculosis_H37Rv SHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV MAB_4098c|M.abscessus_ATCC_199 GGWSLLVPDTGTVDARACLRVAESLSDAELVAARSRLNPAAGAQLSAVWV MAV_3243|M.avium_104 GGWNLQAPEPGSVRAADCLQSVDTLSDAVLVAARSRLNPGAGVMVSAVWA MSMEG_0402|M.smegmatis_MC2_155 DEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWV TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M DSLALLIYTSGSTGAPKGAMYPRRNVATFWRKR--------------TWF MUL_1722|M.ulcerans_Agy99 DSLALLIYTSGSTGAPKGAMYPRRNVATFWRKR--------------TWF MLBr_00484|M.leprae_Br4923 DPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRSD------------GNWF Mvan_2578|M.vanbaalenii_PYR-1 DALSLLIYTSGSTGAPKGAMYPQHLVANSWRRLAR-----------SFWG Mflv_2696|M.gilvum_PYR-GCK NRVAHWLIGQG-IGAEDRVAVLMDRSPELLITALGIIKAGAVYLPVDPSY Mb0104|M.bovis_AF2122/97 RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRL Rv0101|M.tuberculosis_H37Rv RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRL MAB_4098c|M.abscessus_ATCC_199 PDSRQLALMIHHLAVDGVSWRILLEDLNIAWAQHHGGQPVQLPAGGTSFA MAV_3243|M.avium_104 SETSQLALIIHHVAVDGVSWRTLIEDLNIAWAQHHSGQPVALPAGGTSFA MSMEG_0402|M.smegmatis_MC2_155 RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M EGGYEPSITLNFMPMSHVMGRQILYGT--------------LCNGGTAYF MUL_1722|M.ulcerans_Agy99 EGGYEPSITLNFMPMSHVMGRQILYGT--------------LCNGGTAYF MLBr_00484|M.leprae_Br4923 G-PTAASITLNFMPMSHVMGRGILYGT--------------LGNGGTAYF Mvan_2578|M.vanbaalenii_PYR-1 DLGVFPAITLNFMPMSHVMGRGLLYGT--------------LDAGGTAYF Mflv_2696|M.gilvum_PYR-GCK PQDRMSFVLSDSDPTLVIREPVAGLDGHRTDNPTDDVRVRPLRPENAAYL Mb0104|M.bovis_AF2122/97 RQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCD Rv0101|M.tuberculosis_H37Rv RQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCD MAB_4098c|M.abscessus_ATCC_199 RWAALLDEHARSQDVVATAD--AWREVTAVPAALPAVMPGLDTYATAKTL MAV_3243|M.avium_104 RWSSLLAEHALTPAVVEQAD--AWREVVATPAVLPAVQPEVDTYQSAEQL MSMEG_0402|M.smegmatis_MC2_155 RWSALLAEHAKTDTVRDLAD--AWRAVTSVPQALPPVQPDTDTYVTAGQL TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -----------------------------------VAKSDLSTLFEDLAL MUL_1722|M.ulcerans_Agy99 -----------------------------------VVKSDLSTLFEDLAL MLBr_00484|M.leprae_Br4923 -----------------------------------AARSDLSTLLEDLKL Mvan_2578|M.vanbaalenii_PYR-1 -----------------------------------AARSDLSTFLEDLAL Mflv_2696|M.gilvum_PYR-GCK IYTSG-----------------------STGQPKGVPVPHRPVAEYFVWF Mb0104|M.bovis_AF2122/97 QTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVT Rv0101|M.tuberculosis_H37Rv QTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVT MAB_4098c|M.abscessus_ATCC_199 SVSLDADTTRELLSEVPAAFHAGVQDILLIAFGLAWNEFLDSNTTSIGIG MAV_3243|M.avium_104 SVSLDVDTTRLLLGEVPAAFHAGVQDILLIAFAMAWTQVVGAG-TPIGID MSMEG_0402|M.smegmatis_MC2_155 SASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVD TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M VRPTELTFVPRVWDMVFDEFQSEVDRRLVDG----------ADRVALEAQ MUL_1722|M.ulcerans_Agy99 VRPTELTFVPRVWDMVFDEFQSEVDRRLVDG----------ADRVALEAQ MLBr_00484|M.leprae_Br4923 VRPTELNFVPRIWETLYDESKRAVDRRLANSG--------SADRAAIKAE Mvan_2578|M.vanbaalenii_PYR-1 VRPTQLSFVPRIWDTIHAEVSQELERRPSDA-----------------TE Mflv_2696|M.gilvum_PYR-GCK KDEYEISESDRLLQVASPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAY Mb0104|M.bovis_AF2122/97 AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRI Rv0101|M.tuberculosis_H37Rv AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRI MAB_4098c|M.abscessus_ATCC_199 VEGHGRQEELGRVAGLDIDLSRTVGWFTTKYPVSLSVGGLSWKEIADGSP MAV_3243|M.avium_104 VEGHGRHEELG----PHVDLSRTVGWFTTKYPVALAIDGLDWASVVAGDD MSMEG_0402|M.smegmatis_MC2_155 VEGHGRYDELAS----DVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M VKAEIRNDVLGG----------------------------RYTSALTGSA MUL_1722|M.ulcerans_Agy99 VKAEIRNDVLGG----------------------------RYTSALTGSA MLBr_00484|M.leprae_Br4923 VMDEQRQSLLGG----------------------------RYIAAMTGSA Mvan_2578|M.vanbaalenii_PYR-1 VIADLRRSLLGG----------------------------RYVTAMTGSA Mflv_2696|M.gilvum_PYR-GCK LTELLQREGITAMHFVPSLLGLFLSLPG-------VNQWRTLERVPIGGE Mb0104|M.bovis_AF2122/97 AEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVS Rv0101|M.tuberculosis_H37Rv AEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVS MAB_4098c|M.abscessus_ATCC_199 DLGPIIKSAKEQLRALPDPLTYGLLRYLNPDVDLSGPEPAIGFNYLGRLG MAV_3243|M.avium_104 ALGAAVKAAKEQLRALPDGLTYGLLRYLNPDVDLGGSDPVIGFNYLGRLG MSMEG_0402|M.smegmatis_MC2_155 ALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M PISDEMKAWVEELLDMHLVEGYGS-------------------------- MUL_1722|M.ulcerans_Agy99 PISDEMKAWVEELLDMHLVEGYGS-------------------------- MLBr_00484|M.leprae_Br4923 PTSPELKHGVESLLEMHLLEGYGS-------------------------- Mvan_2578|M.vanbaalenii_PYR-1 PLSPEMRAFVENLLDVHLIDGYGS-------------------------- Mflv_2696|M.gilvum_PYR-GCK ALPGELADRFHATFDALLHNFYGPTET----------------------- Mb0104|M.bovis_AF2122/97 SFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW Rv0101|M.tuberculosis_H37Rv SFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW MAB_4098c|M.abscessus_ATCC_199 AGAADLTDDLWRINEDSLSSAGVASSVSMPLMYTVDLNAGIVEG------ MAV_3243|M.avium_104 A-AADLPGELWRLSPDSLSLSGAAAAVAMPLMHTVDLNAGTMD------- MSMEG_0402|M.smegmatis_MC2_155 AGAGELSEELWRIDQDSLALSDAASAVPMPLMHTVELNAGTID------- TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Mb0104|M.bovis_AF2122/97 SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG--AD Rv0101|M.tuberculosis_H37Rv SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG--AD MAB_4098c|M.abscessus_ATCC_199 ----GLGEEAGPHLRAGWTWAPSSVTEPQVQRLSQLWFEALAGICAYVRG MAV_3243|M.avium_104 -------TEDGPHLHANWTWAPSAVDRDQISRLSQLWFEALAGICAHVRA MSMEG_0402|M.smegmatis_MC2_155 -------TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------TEAGMILIDGAIRRPAVLD------------------------ MUL_1722|M.ulcerans_Agy99 -------TEAGMILIDGAIRRPAVLD------------------------ MLBr_00484|M.leprae_Br4923 -------TEAGMVLFDGEVQRPPVID------------------------ Mvan_2578|M.vanbaalenii_PYR-1 -------TEAGAVFVDGRVQRPPVID------------------------ Mflv_2696|M.gilvum_PYR-GCK -------IINTTRYKVEGTQGSRIVP------------------------ Mb0104|M.bovis_AF2122/97 TAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQR Rv0101|M.tuberculosis_H37Rv TAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQR MAB_4098c|M.abscessus_ATCC_199 GGGGLTPSDIAPAQLSQQQIDELHEQHKIVDVLPLTPIQEGLLFHTTFAR MAV_3243|M.avium_104 GGGGLTPSDILPARLNQRQIDELSKQHQIADILPLTPLQQGLLFHASFAQ MSMEG_0402|M.smegmatis_MC2_155 GGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFAR TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M --------------------------YKLVDVPDLGYFLT---------- MUL_1722|M.ulcerans_Agy99 --------------------------YKLVDVPDLGYFLT---------- MLBr_00484|M.leprae_Br4923 --------------------------YKLVDVPDLGYFST---------- Mvan_2578|M.vanbaalenii_PYR-1 --------------------------YKLVDVADLGYFST---------- Mflv_2696|M.gilvum_PYR-GCK --------------------------IGTPKINTTVHLLDD--------- Mb0104|M.bovis_AF2122/97 PAP----------VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Rv0101|M.tuberculosis_H37Rv PAP----------VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF MAB_4098c|M.abscessus_ATCC_199 AAGALEGDEAGIDFYAVQLDITVTGLVDQLRLRDAVHTVVRRHPNLAARF MAV_3243|M.avium_104 DP--------GDDVYAVQLGITVTGALDSHRLHDAVHTVVNRHPNLAARF MSMEG_0402|M.smegmatis_MC2_155 GI--------GDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Mb0104|M.bovis_AF2122/97 PAVDGVPRQLVIEARRADLG-CDIVDATAWPADRLQRAIEEAARHSFDLA Rv0101|M.tuberculosis_H37Rv PAVDGVPRQLVIEARRADLG-CDIVDATAWPADRLQRAIEEAARHSFDLA MAB_4098c|M.abscessus_ATCC_199 CTQFGDPVQVILADPVIAWRYLDLRGDDLTPDEEIQHLCAAERAAVCDLA MAV_3243|M.avium_104 CPQYGEPVQVVPADPVMAWRYIQLGPEDVDPEQKVEELCAAERAAVSDLA MSMEG_0402|M.smegmatis_MC2_155 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLL TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------A Mb0104|M.bovis_AF2122/97 TEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAG Rv0101|M.tuberculosis_H37Rv TEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAG MAB_4098c|M.abscessus_ATCC_199 DRPTLRAALIRTEGNQHRFVLTFHHVVIDGWSLPILLQEIFASYFGHRLP MAV_3243|M.avium_104 NRPAFRAALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYGDQLP MSMEG_0402|M.smegmatis_MC2_155 ERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M DRPHPRGELLVKTDS------------------------LFPGYYQRAEV MUL_1722|M.ulcerans_Agy99 DRPHPRGELLVKTDS------------------------LFPGYYQRAEV MLBr_00484|M.leprae_Br4923 DQPYPRGELLLKTQN------------------------MFPGYYKRPEV Mvan_2578|M.vanbaalenii_PYR-1 DRPHPRGELLVKSET------------------------LFPGYYKRPDV Mflv_2696|M.gilvum_PYR-GCK LRPVPVGAIGEIYIGG---------------------GHVARGYHRRPAL Mb0104|M.bovis_AF2122/97 RAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPER Rv0101|M.tuberculosis_H37Rv RAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPER MAB_4098c|M.abscessus_ATCC_199 APSSYRSFVSWLADQDLDAARTAWGKVLEGFDTPTLVAPP--------AP MAV_3243|M.avium_104 APATYRSYLTWLAGQDRSAAQAAWRQVLDGFDTPTLVGPAG------RMR MSMEG_0402|M.smegmatis_MC2_155 AAAPYRNFVNWLATQDATAAKAAWREVLDGFETPTLVAPPG--------V TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M TADVFD-------------------------------------------- MUL_1722|M.ulcerans_Agy99 TADVFD-------------------------------------------- MLBr_00484|M.leprae_Br4923 TATVFD-------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 TAEMFD-------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK TAERFVADP----------------------------------------- Mb0104|M.bovis_AF2122/97 LRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAG Rv0101|M.tuberculosis_H37Rv LRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAG MAB_4098c|M.abscessus_ATCC_199 PGARGVESYRVSAE-------------TTQALGDLARSQHTTVSTVLQAA MAV_3243|M.avium_104 LGRRAVESYRLSAD-------------TTRALGELARACHTTVNTVLQAG MSMEG_0402|M.smegmatis_MC2_155 PGPRGIESYRVSAE-------------TTRALGELARSQHTTINTVLQAA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -----ADGFYRTGD-------------IMAEVGPEQFVYLDRRNNVLKLS MUL_1722|M.ulcerans_Agy99 -----ADGFYRTGD-------------IMAEVGPEQFVYLDRRNNVLKLS MLBr_00484|M.leprae_Br4923 -----SDGYYQTGD-------------IVAEVGPDRLVYVDRRNNVLKLA Mvan_2578|M.vanbaalenii_PYR-1 -----EDGYYRTGD-------------IVAETGADQLTYLDRRNNVLKLS Mflv_2696|M.gilvum_PYR-GCK --FTVGGRLYRSGD-------------LARRNADGDLEFVGRADDQVKIR Mb0104|M.bovis_AF2122/97 LAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGD Rv0101|M.tuberculosis_H37Rv LAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGD MAB_4098c|M.abscessus_ATCC_199 WAQLLMVLTGQDDVAFGTAVSGRPAELAGSDSIVGLLINTVPVRARATAS MAV_3243|M.avium_104 WAQLLMRLTGQHDVAFGTAVSGRPADLAGAESMVGLLINTVPVRANTHAE MSMEG_0402|M.smegmatis_MC2_155 WTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK G------------------------------------------------- Mb0104|M.bovis_AF2122/97 PSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAW Rv0101|M.tuberculosis_H37Rv PSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAW MAB_4098c|M.abscessus_ATCC_199 TTIAELLGQLQSAHNDTIEHEHLALNEIHH------VAGHEQLFDTLFLY MAV_3243|M.avium_104 TTVADLLDQLQQHHNDTLEHEHLALSEIHR------VTGHDALFDTLFLY MSMEG_0402|M.smegmatis_MC2_155 TTVGDLLRQLQSHHNDTLEHEHLALNDIHH------VSGHEQLFDTLFLY TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M ------------------QGEFVTVSKLEA------VFGDSPLVRQIYIY MUL_1722|M.ulcerans_Agy99 ------------------QGEFVTVSKLEA------VFGDSPLVRQIYIY MLBr_00484|M.leprae_Br4923 ------------------QGQFVTVAKLEA------AFSNSPLVRQIYIY Mvan_2578|M.vanbaalenii_PYR-1 ------------------QGEFVTVSRLEA------VFGNSPLVRQIYVY Mflv_2696|M.gilvum_PYR-GCK --------------FRIELGEVAAAISVDPSVGQAVVLGQDLPGLGMSLV Mb0104|M.bovis_AF2122/97 QDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAV Rv0101|M.tuberculosis_H37Rv QDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAV MAB_4098c|M.abscessus_ATCC_199 ESYPIDTSAFMGVQELAITEFVTREYNHYPLSVMALPGHE-----LGIRV MAV_3243|M.avium_104 ENYPIDTSVPLGFHELAITDVTNREYNHYPLSVMALPGRE-----LGLRV MSMEG_0402|M.smegmatis_MC2_155 ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE-----LGLRV TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M G------------------------------------------------- MUL_1722|M.ulcerans_Agy99 G------------------------------------------------- MLBr_00484|M.leprae_Br4923 G------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 G------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK G------------------------------------------------- Mb0104|M.bovis_AF2122/97 EYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDE Rv0101|M.tuberculosis_H37Rv EYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDE MAB_4098c|M.abscessus_ATCC_199 EYDTDKFGLDDIQAVFERFERVLVSMVSDADQRLSSLDVLQTDEHKQLDG MAV_3243|M.avium_104 EFDTDVFDAAGIEKLTERFQRVLSEMTADPTRRLTSLEVMDEAEHELLDA MSMEG_0402|M.smegmatis_MC2_155 EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDE TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Mb0104|M.bovis_AF2122/97 WGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEAS Rv0101|M.tuberculosis_H37Rv WGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEAS MAB_4098c|M.abscessus_ATCC_199 WGNRKVLVRGPEPVLSIPEAFAEQVDRAPEAVALTFEGRSTTYGELDEAA MAV_3243|M.avium_104 WGNRPVLS-QPATGTSIPALFAAQVARTPDAAALTFQGRSMSYRELDEAS MSMEG_0402|M.smegmatis_MC2_155 WANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAA TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Mb0104|M.bovis_AF2122/97 NRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANP Rv0101|M.tuberculosis_H37Rv NRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANP MAB_4098c|M.abscessus_ATCC_199 NRLANLLSVYGAAPGESVALLMPRSDEAIIAILAILKTGASYLPIDPSVP MAV_3243|M.avium_104 NRLAHLLIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALP MSMEG_0402|M.smegmatis_MC2_155 NQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------NSARAYLLAVIVP------------ MUL_1722|M.ulcerans_Agy99 -------------------------NSARAYLLAVIVP------------ MLBr_00484|M.leprae_Br4923 -------------------------NSAHPYLLAVVVP------------ Mvan_2578|M.vanbaalenii_PYR-1 -------------------------NSARPYLLAVVVP------------ Mflv_2696|M.gilvum_PYR-GCK ----------YVTPAAGEDVDLARVRERVAAALPDYMTPAGYVVLDEIPI Mb0104|M.bovis_AF2122/97 PPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPG----- Rv0101|M.tuberculosis_H37Rv PPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPG----- MAB_4098c|M.abscessus_ATCC_199 DTRLEFMLSDAVPIAAVTTAELRARFDGSGVSVVQFDDAEDDPTGAIYGH MAV_3243|M.avium_104 AARIEFLLGDAEPVAVVTTAALRSRLDGCKPSVVDVDDPALDGQ----PS MSMEG_0402|M.smegmatis_MC2_155 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIY----PS TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M ---------TQEALDAVPVEELKARLGDSLQEVAKAAG------------ MUL_1722|M.ulcerans_Agy99 ---------TQEALDAVPVEELKARLGDSLQEVAKAAG------------ MLBr_00484|M.leprae_Br4923 ---------TEDALATNDIEVLKPLIIDSLQKVAKEAD------------ Mvan_2578|M.vanbaalenii_PYR-1 ---------TEAALAG---ADAKAAVAESLQDVAKATG------------ Mflv_2696|M.gilvum_PYR-GCK TAHGKIDRAALPLPEITTATDYREPQTETEQHLAQLFSELLGVAR----- Mb0104|M.bovis_AF2122/97 TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS--AA Rv0101|M.tuberculosis_H37Rv TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS--AA MAB_4098c|M.abscessus_ATCC_199 TPLLTPAPDDIAYTIYTSGTTGVPKGVAIAHSNVTQALKFPLTHMPTGPG MAV_3243|M.avium_104 AALPVPSSDNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLPEG-- MSMEG_0402|M.smegmatis_MC2_155 TTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -----------------LQSYEIPR------------------------- MUL_1722|M.ulcerans_Agy99 -----------------LQSYEIPR------------------------- MLBr_00484|M.leprae_Br4923 -----------------LQSYEVPR------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -----------------LQSYEIPR------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------VGVDDSFFELGGHSLLATKLVSAVRSRCGVDMEIREI Mb0104|M.bovis_AF2122/97 QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEH Rv0101|M.tuberculosis_H37Rv QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEH MAB_4098c|M.abscessus_ATCC_199 EVWTQAGSLVFDITVWEIFGALLHGGRLVIIPDSVVRSPDDFRDLLIREK MAV_3243|M.avium_104 GVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHDLLVAEG MSMEG_0402|M.smegmatis_MC2_155 AVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------DFIIETTPWTLENGLLTGIRKLARPQ----------------- MUL_1722|M.ulcerans_Agy99 -------DFIIETTPWTLQNGLLTGIRKLARPQ----------------- MLBr_00484|M.leprae_Br4923 -------DLIVETTPFSLENGLLTGIRKLAWPK----------------- Mvan_2578|M.vanbaalenii_PYR-1 -------DFLLETTPFTLENGLLTGIRKLARPR----------------- Mflv_2696|M.gilvum_PYR-GCK FELGTVARLAERVDELAAGGSAPLRPRLLAVPHDG------------PAP Mb0104|M.bovis_AF2122/97 VSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYG Rv0101|M.tuberculosis_H37Rv VSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYG MAB_4098c|M.abscessus_ATCC_199 VTVLFQTPSAVGMLSPEGLNNLTLVVAGEACPTEVVDRWAPGRVMINGYG MAV_3243|M.avium_104 VTVLSQTPSAVGMLSPEGLDSTALVVAGEACPVEIVDRWAPGRVMINAYG MSMEG_0402|M.smegmatis_MC2_155 VNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYG TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M --------------------------------------------LKKHYG MUL_1722|M.ulcerans_Agy99 --------------------------------------------LKKHYG MLBr_00484|M.leprae_Br4923 --------------------------------------------LKQHYG Mvan_2578|M.vanbaalenii_PYR-1 --------------------------------------------LRERYG Mflv_2696|M.gilvum_PYR-GCK MSAAQLRQWFQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHE Mb0104|M.bovis_AF2122/97 PTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGEL Rv0101|M.tuberculosis_H37Rv PTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGEL MAB_4098c|M.abscessus_ATCC_199 PTETTIYATFG-ELIAGSGVVPIGVPVPDAALFVLDRWMRPVPPGVVGEL MAV_3243|M.avium_104 PTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPPGVVGEL MSMEG_0402|M.smegmatis_MC2_155 PTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGEL TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK SLRTTFCEIDG--------------------------------------- Mb0104|M.bovis_AF2122/97 YIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADG--- Rv0101|M.tuberculosis_H37Rv YIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADG--- MAB_4098c|M.abscessus_ATCC_199 YVAGLGVGIGYVKRQALTAARFVACPFGEPGTRMYRTGDLVRWGVSESSV MAV_3243|M.avium_104 YIAGHGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQD---- MSMEG_0402|M.smegmatis_MC2_155 YLAGRGVGVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWGDD---- TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -QLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDK Rv0101|M.tuberculosis_H37Rv -QLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDK MAB_4098c|M.abscessus_ATCC_199 GQLEYLGRADEQVKIRGFRIELGEIQAALADVDGVEQAAVIAREDRPGDK MAV_3243|M.avium_104 GQLEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDK MSMEG_0402|M.smegmatis_MC2_155 GQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDK TH_1879|M.thermoresistible__bu -------------------------------------------------- MMAR_2117|M.marinum_M -------------------------------------------------- MUL_1722|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00484|M.leprae_Br4923 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK --------------------------VPYQLVNAPDPGFPVRRDSGPDDA Mb0104|M.bovis_AF2122/97 RLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL Rv0101|M.tuberculosis_H37Rv RLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL MAB_4098c|M.abscessus_ATCC_199 RLVGYFIGTGE----PAELRAALAKRLPPYMVPAALVRLEALPLTVNGKL MAV_3243|M.avium_104 RLVGYITGTAD----PVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKL MSMEG_0402|M.smegmatis_MC2_155 RLVGYITGTAD----PAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKL TH_1879|M.thermoresistible__bu --VGLSX----------QARARLADRLPAYMVPAAVVVLDRIPLTVNGKL MMAR_2117|M.marinum_M ---------------------ELLEQIYTDLAHGQADELRSLRQSG---- MUL_1722|M.ulcerans_Agy99 ---------------------ELLEQIYTDLAHGQADELRSLRQSG---- MLBr_00484|M.leprae_Br4923 ---------------------ARLEQLYADLVEGQANALHVLKQSV---- Mvan_2578|M.vanbaalenii_PYR-1 ---------------------EQLEALYTMLSEEQADELRELRRSG---- Mflv_2696|M.gilvum_PYR-GCK WLVGALDDERR----RVFDLENQWPIRVAVLSIPGEHALSVVVHHIAADH : : : Mb0104|M.bovis_AF2122/97 DHRALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLG--LERVGVDDSFF Rv0101|M.tuberculosis_H37Rv DHRALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLG--LERVGVDDSFF MAB_4098c|M.abscessus_ATCC_199 DKRALPAPEYDDAAR-YRAPANAVEEAVAGIYAQVLG--VERVGTDDSFF MAV_3243|M.avium_104 DKRALPAPEYRKRGGEYIAPTNPTEETVAGIFARVLG--MERVSIDDSFF MSMEG_0402|M.smegmatis_MC2_155 DRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLG--VERIGLDDSFF TH_1879|M.thermoresistible__bu DRRALPAPEYQRADR-YRAPETAVEKTLTEIFAHVLG--LERVGVDDSFF MMAR_2117|M.marinum_M -------------------ADAPVLVTVCRAAAALLGGSASDVQPDAHFT MUL_1722|M.ulcerans_Agy99 -------------------ADAPVLVTVCRAAAALLGGSASDVQPDAHFT MLBr_00484|M.leprae_Br4923 -------------------ANAPVLQTVSRAVGTILGVATTDLPSNAHFT Mvan_2578|M.vanbaalenii_PYR-1 -------------------GERPALETVGRAAGALLGTTAGELEPSAHFT Mflv_2696|M.gilvum_PYR-GCK WSGGVLFTELLTAYRARRAGEAPTWAPLPVQYADYAAWQSALLADDSGIV . .: . . : . : Mb0104|M.bovis_AF2122/97 ELGGDSLAAMRVIAAINTTLNADLPVRALLH-ASSTRGLSQLLGRDARPT Rv0101|M.tuberculosis_H37Rv ELGGDSLAAMRVIAAINTTLNADLPVRALLH-ASSTRGLSQLLGRDARPT MAB_4098c|M.abscessus_ATCC_199 DLGGDSISAMRVVAAINTSFDAQLAVRTLFE-APSVRSLSGYLDGAAGAP MAV_3243|M.avium_104 ELGGDSLSAMRVIAEINTAVDGALSVRTLFD-SQSVRALSQRITSGADAE MSMEG_0402|M.smegmatis_MC2_155 DLGGDSISAMRVTAAVNTALDADLSVRTLFE-APTVAKLSLHVEHDAGER TH_1879|M.thermoresistible__bu DLGGDSISAMRAVAAINTALDTDVAVRTLFE-APTVRRLSRQLEGGADTA MMAR_2117|M.marinum_M DLGGDSLSALSFTNLLHEIFDIEVPVGVIVSPANDLQALADYVEAARKPG MUL_1722|M.ulcerans_Agy99 DLGGDSLSALSFTNLLHEIFDIDVPVGVIVSPANDLQALADYVEAARKPG MLBr_00484|M.leprae_Br4923 DLGGDSLSALTFGSLLRELFDIDVPVGVIVSPVNNLVAIADYIERERQ-G Mvan_2578|M.vanbaalenii_PYR-1 DLGGDSLSALTFANLLRDIFDVDVPVGVIVSPATDLQALADYVESARRHG Mflv_2696|M.gilvum_PYR-GCK AAQRRYWTQQLEGLSAETGLQPDLVRPSVPSGAADAVEFTLDAAIREKLV : . .: : : :: Mb0104|M.bovis_AF2122/97 S------DPRLVSVHGDNPT---EVHAS-DLTLDRFIDADTLATAVNLPG Rv0101|M.tuberculosis_H37Rv S------DPRLVSVHGDNPT---EVHAS-DLTLDRFIDADTLATAVNLPG MAB_4098c|M.abscessus_ATCC_199 -----ANGPTYASVHGPGAT---EVRAS-DLTLDKFIDEATLQKAPTLPR MAV_3243|M.avium_104 N----AAGPGFAAVHGADAK---EVYAR-DLTLDKFLDATTLSTAPTLPG MSMEG_0402|M.smegmatis_MC2_155 -----TDRVSFAAVHGSDVT---EVHAR-DLTLDKFIDAPTLRTATTLPR TH_1879|M.thermoresistible__bu PQGADLGAVTYESVHGATAT---EVRAA-DLTLDRFIDAATLRTAADLPR MMAR_2117|M.marinum_M S-----SRPTFASVHGASNGQVTEVHAG-DLSLDKFIDAATLAEAPRLPA MUL_1722|M.ulcerans_Agy99 S-----SRPTFASVHGASNEQVTEVHAG-DLSLDKFIDAATLAEAPRLPA MLBr_00484|M.leprae_Br4923 T-----KRPTFIAIHGRDAG---KVHAS-DLTLDKFIDVSTLTAAPVLAQ Mvan_2578|M.vanbaalenii_PYR-1 S-----VRPTFESVHGHSGRPGTEVHAR-DLTLDEFVDAATLAHAPTLPG Mflv_2696|M.gilvum_PYR-GCK TLSREVGATEFMLLQAAVAVTLYKAGEGPDIPLGTPVAGRTESELDQLIG ::. :. *:.*. : * * Mb0104|M.bovis_AF2122/97 PSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDEDARR Rv0101|M.tuberculosis_H37Rv PSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDEDARR MAB_4098c|M.abscessus_ATCC_199 AEATARTVLLTGATGFLGRYLVLQWLRELEQVDGTLICLVRAKSDEEARR MAV_3243|M.avium_104 PSPEVRTVLLTGATGFLGRYLVLEWLEQLEQVDGKLICLVRARSDEEAWG MSMEG_0402|M.smegmatis_MC2_155 PDGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARR TH_1879|M.thermoresistible__bu PTGQVQTVLLTGATGFLGRYLLLEWLRRLRRVDDTVICLVRGRSDADARQ MMAR_2117|M.marinum_M ANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRAKSDTEARA MUL_1722|M.ulcerans_Agy99 ANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRAKSDTEARA MLBr_00484|M.leprae_Br4923 PGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALVRAKSNEDARA Mvan_2578|M.vanbaalenii_PYR-1 PRAEVRTVLLTGATGFLGRYLALEWLERMALVGGKLICLVRAKDDAAARV Mflv_2696|M.gilvum_PYR-GCK --FFINILVLRNDLRDNPSLRDVGFRSREMALAAYAHQDLPFDQVVDAVS . ::* . : . : : . * Mb0104|M.bovis_AF2122/97 RLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAE- Rv0101|M.tuberculosis_H37Rv RLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAE- MAB_4098c|M.abscessus_ATCC_199 RLDKTFDSGDPELIRVYEALAADRLQVIAGDKAEPSLGLDQDTWQRLAD- MAV_3243|M.avium_104 RLEKTFNTGDPELLRHFQELAEEHLQVVAGDKGQANLGLDEQTWQQLAD- MSMEG_0402|M.smegmatis_MC2_155 RLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAE- TH_1879|M.thermoresistible__bu RLEAVFDT-DPALRRHFRELAAERLQVIAGDKGQPNLGLDVQTWRRLAE- MMAR_2117|M.marinum_M RLDKTFDSGDPELLAHYRALAGDHLEVLAGDKGEADLGLDRQTWQRLAD- MUL_1722|M.ulcerans_Agy99 RLEKTFDSGAPELLAHYRALAGDHLEVLAGDKGEADLGLDRQTWQRLAD- MLBr_00484|M.leprae_Br4923 RLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELDRQTWRRLAD- Mvan_2578|M.vanbaalenii_PYR-1 RLDSTFDSGDPELLRHYRRLAADHLEVIAGDKADADLGLDARTWQRLAD- Mflv_2696|M.gilvum_PYR-GCK PVRSLSRNPLFGVVVHVREELPQDRVIATGSDGETTFTALEPTFDMAHAD : . : . : : :*...: : : Mb0104|M.bovis_AF2122/97 -TVDLIVDSAAMVN-AFPYHELFGPNVAG--TAELIRIALTTKLKPFTYV Rv0101|M.tuberculosis_H37Rv -TVDLIVDSAAMVN-AFPYHELFGPNVAG--TAELIRIALTTKLKPFTYV MAB_4098c|M.abscessus_ATCC_199 -TVDLIVDSAALVNSVLPYSELFGPNVVG--TAELIRFALTTKLKPYTYI MAV_3243|M.avium_104 -TVDLIVDSAAVVNGVLPYSELFTPNVGG--TAELIRLALTTRKKPFAYV MSMEG_0402|M.smegmatis_MC2_155 -SVDLIVDSAAFVNSVLPYSELFGPNVVG--TAELIRFALTSKLKPFNFV TH_1879|M.thermoresistible__bu -RVDLIVDSAAFVNSVLPYRELFGPNVVG--TAELIRFALTAKLKPYNFV MMAR_2117|M.marinum_M -TVDLIVDPAALVNHVLPYSQLFGPNALG--TAELLRLALTSKIKPYSYT MUL_1722|M.ulcerans_Agy99 -TVDLIVDPAALVNHVLPYSQLFGPNALG--TAELLRLALTSKIKPYSYT MLBr_00484|M.leprae_Br4923 -TVDLIVDPAALVNHVLPYSELFGPNTLG--TAELIRIALTSKQKPYIYV Mvan_2578|M.vanbaalenii_PYR-1 -TVDLIVDPAALVNHVLPYRQLFAPNVLG--TAELLRIALTTRMKPFVYV Mflv_2696|M.gilvum_PYR-GCK LSVNFFAGGNGYRGHVIYRTELYTRATAERFAGWLSAVITAFADDPERHV *:::.. . . .: :*: . :. * . : .* . Mb0104|M.bovis_AF2122/97 STADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTS--KWAGEVLL Rv0101|M.tuberculosis_H37Rv STADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTS--KWAGEVLL MAB_4098c|M.abscessus_ATCC_199 STADVGREIEKSVFREDADIRVISATRPSDGSYANGYGNS--KWAGEVLL MAV_3243|M.avium_104 STSDVGRQIEPSAFTEDADIRVISATRVIDGSYANGYGNS--KWAGEVLL MSMEG_0402|M.smegmatis_MC2_155 STSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNS--KWAGEVLL TH_1879|M.thermoresistible__bu STSDIGRQIEPDLFTEDADIRTISPTRTVDASYANGYGNS--KWAGEVLL MMAR_2117|M.marinum_M STIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNS--KWAGEVLL MUL_1722|M.ulcerans_Agy99 STIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNS--KWAGEVLL MLBr_00484|M.leprae_Br4923 STIGVGNQIEPAKFTEDSDIRVISPTRNINNNYANGYGNS--KWAGEVLL Mvan_2578|M.vanbaalenii_PYR-1 STIGVGAGIEPARFTEDADIRQISATRRIDDSYANGYGNS--KWAGEVLL Mflv_2696|M.gilvum_PYR-GCK DDVVIAEPVRPGDGAEAVLLDGAGHPVPVGVVADVHYAGAPDRRGDRARW . :. : * : . . *. : : .... Mb0104|M.bovis_AF2122/97 REANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPR Rv0101|M.tuberculosis_H37Rv REANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPR MAB_4098c|M.abscessus_ATCC_199 REAHEQVGLPVKVFRSGMIMVDTSYAGQVNASDTVARMVLSVVATGVAPY MAV_3243|M.avium_104 REAHDLCGLPVSVFRSDMILADTSYAGQLNVTDIFTRMILSIVATGTAPK MSMEG_0402|M.smegmatis_MC2_155 REAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPG TH_1879|M.thermoresistible__bu REAHDLCGLPVAVFRSGMILVDPTYAGQLNVTDTVSRMVLSIVATGVAPK MMAR_2117|M.marinum_M REAHDLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATGIAPG MUL_1722|M.ulcerans_Agy99 REAHVLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATGIAPG MLBr_00484|M.leprae_Br4923 REAHDLCGLPVTVFRCDMILADTSYAGQLNVPDMFTRMMLSLAATGIAPG Mvan_2578|M.vanbaalenii_PYR-1 REAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTRLIFSLVATGVAPE Mflv_2696|M.gilvum_PYR-GCK TEDGRLQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYVVPAE * : . :. . .. :: . .. Mb0104|M.bovis_AF2122/97 SFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAG----FATY Rv0101|M.tuberculosis_H37Rv SFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAG----FATY MAB_4098c|M.abscessus_ATCC_199 SVYQLDADGNRQRAHFDGLPVEFVAEAITALGGGAAGSFDGSAD--FETY MAV_3243|M.avium_104 SFYRLDADGNRQRSHFDALPVEFVAEAIAKLG---AQVMDG-----FETY MSMEG_0402|M.smegmatis_MC2_155 SFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETY TH_1879|M.thermoresistible__bu SFYRLGDDGSRQRAHFDGLPVDFVAEAVATLGWQIARTATGSPAGDFRTY MMAR_2117|M.marinum_M SFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----FHTY MUL_1722|M.ulcerans_Agy99 SFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----FHTY MLBr_00484|M.leprae_Br4923 SFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQSLHDRDG-----FTTY Mvan_2578|M.vanbaalenii_PYR-1 SFYHLATDGTRQRAHYDGLPVEFIAEAISTLGSD---VASG-----FRTY Mflv_2696|M.gilvum_PYR-GCK PVDDPASFAETVRAAVAPESAPTSITVLDALPATRRALPAPRVG-GPSEP .. . *: .. .: * Mb0104|M.bovis_AF2122/97 HVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQ Rv0101|M.tuberculosis_H37Rv HVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQ MAB_4098c|M.abscessus_ATCC_199 HVMNPHDDGIGIDEYVDWLIEAGHPIERIDDFGEWVRQFEARLHALPDHQ MAV_3243|M.avium_104 HVMNPHDDGIGLDEYVDWLIEAGYPIERVDDFGEWLQRFETGLRGLPERQ MSMEG_0402|M.smegmatis_MC2_155 HVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQ TH_1879|M.thermoresistible__bu HVMNPHDDGIGIDEYVDWLIEAGHPIERIDDFGEWLRRFEAGLHALPERQ MMAR_2117|M.marinum_M HVMNPYDDGIGLDEFVDWLNESGCPIQRIADYGDWLQRFETALRALPDRQ MUL_1722|M.ulcerans_Agy99 HVMNPYDDGIGLDEFVDWLNESGCPIQRIADYGDWLQRFETALRALPDRQ MLBr_00484|M.leprae_Br4923 HVMNPHDDGIGMDEFVDWLIDAGCPIQRINDYDEWLRRFEISLRALPERQ Mvan_2578|M.vanbaalenii_PYR-1 HVMNPHDDGIGLDEYVDWLIDAGHPIRRVGDYPTWLQRFTVAITALPERQ Mflv_2696|M.gilvum_PYR-GCK ARTDTEKALVGMLADVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAK :. . :*: : . * * *. *: : . : Mb0104|M.bovis_AF2122/97 RRHSVLPMLLASNSQ--RLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDN Rv0101|M.tuberculosis_H37Rv RRHSVLPMLLASNSQ--RLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDN MAB_4098c|M.abscessus_ATCC_199 RQGSVLQMLKILQDHGWDGQPPEPVRGPMAPADRFHAAVRKAKIGSDHD- MAV_3243|M.avium_104 RQNSVLQMLLLLLRDPKNLQLAEPARGAFAPTDRFRAAVQEAKVGSDND- MSMEG_0402|M.smegmatis_MC2_155 RQNSVLQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGE- TH_1879|M.thermoresistible__bu RQHSVLQMLTLLRQQGGEPQPPEPRHGSDAPADRFEAAVKRAGINGGQG- MMAR_2117|M.marinum_M RHSSLLPLLHNYR------QPERPVRGSIAPTDRFRAAVQEAKIGPDKD- MUL_1722|M.ulcerans_Agy99 RHSSLLPLLHNYR------QPERPVRGSIAPTDRFRAAVQEAKIGPDKD- MLBr_00484|M.leprae_Br4923 RHSSLLPLLHNYQ------KPEKPLHGSLAPTIRFRTAVQNANIGQDKD- Mvan_2578|M.vanbaalenii_PYR-1 RQASLLPLLHNYQ------HPETPIRGSIAPTDRFREAVQDAKIGPDKD- Mflv_2696|M.gilvum_PYR-GCK QAGLRLSARMVFEHP-------VVHDLAVALDTAKTPEVADVRHDPMSAS : * * * . . Mb0104|M.bovis_AF2122/97 PDIPHVSAPTIINYVTNLQLLGLL Rv0101|M.tuberculosis_H37Rv PDIPHVSAPTIINYVTNLQLLGLL MAB_4098c|M.abscessus_ATCC_199 --IPQVSAPIIAKYASDLQLHGLL MAV_3243|M.avium_104 --IPHISAPVIVKYVTDLQLLGLL MSMEG_0402|M.smegmatis_MC2_155 --IPHVTREVIVKYVTDLQLLGLL TH_1879|M.thermoresistible__bu --IPHVTPEVIVRYVTDLRQLGLL MMAR_2117|M.marinum_M --IPHVGAPIIVKYVSDLRLLGLL MUL_1722|M.ulcerans_Agy99 --IPHVGAPIIVKYVSDLRLLGLL MLBr_00484|M.leprae_Br4923 --IPHISPAIIAKYVSDLQLLGLV Mvan_2578|M.vanbaalenii_PYR-1 --IPHVTPQIVIKYVTDLQRLGLL Mflv_2696|M.gilvum_PYR-GCK GLTPEELAMVATSWAAEQDGSP-- *. :.::