For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3141 | - | - | 100% (1785) | amino acid adenylation domain |
| M. thermoresistible (build 8) | TH_3730 | - | e-134 | 32.77% (1236) | PUTATIVE linear gramicidin synthetase subunit D |
| M. thermoresistible (build 8) | TH_3146 | - | 4e-85 | 28.97% (1032) | PUTATIVE amino acid adenylation domain |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2401c | mbtE | 0.0 | 69.33% (1738) | peptide synthetase MBTE (peptide synthase) |
| M. gilvum PYR-GCK | Mflv_2696 | - | 0.0 | 61.96% (1822) | amino acid adenylation domain-containing protein |
| M. tuberculosis H37Rv | Rv2380c | mbtE | 0.0 | 69.33% (1738) | peptide synthetase MBTE (peptide synthase) |
| M. leprae Br4923 | MLBr_01051 | xclC | 2e-24 | 28.57% (490) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2122 | - | 0.0 | 44.23% (1551) | putative peptide synthetase MbtE |
| M. marinum M | MMAR_3691 | mbtE | 0.0 | 43.02% (1562) | non-ribosomal peptide synthetase MbtE |
| M. avium 104 | MAV_2013 | - | 0.0 | 66.30% (1558) | linear gramicidin synthetase subunit D |
| M. smegmatis MC2 155 | MSMEG_4511 | - | 0.0 | 62.57% (1870) | linear gramicidin synthetase subunit B |
| M. ulcerans Agy99 | MUL_3634 | mbtE | 0.0 | 43.23% (1552) | non-ribosomal peptide synthetase MbtE |
| M. vanbaalenii PYR-1 | Mvan_3845 | - | 0.0 | 68.16% (1784) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu VTDTTETRPAGADDEARLALLRRRLSERGLSA--QQTTG---AASEDR--
Mvan_3845|M.vanbaalenii_PYR-1 ---MTDIDTGALLDERRLELLRRRMQERGLSAGTDTAEP---AGDTDV--
MSMEG_4511|M.smegmatis_MC2_155 MTDIADTATAS-TVEARLELMRRKLAERGLAAGRAAAEGSAAAVDPTV--
Mflv_2696|M.gilvum_PYR-GCK -------MTDTDLDARRLELLRRRLAGSGLRE-QDPAEPVAVAADPARGE
MAV_2013|M.avium_104 --MTETTGAGTRLDDERLELLRRKLAERGLSRSAGTARH-----DEPR--
MMAR_3691|M.marinum_M -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPGICPGERYR--
MUL_3634|M.ulcerans_Agy99 -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPRICPGERYR--
MAB_2122|M.abscessus_ATCC_1997 -----MTGDQLSALDRRRELLRRRLAESGVAAQAVESAPRVQAGERRG--
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 -------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHR
Rv2380c|M.tuberculosis_H37Rv -------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHR
TH_3141|M.thermoresistible__bu LSDGQLRMWFVHQADPSGALLNICLSYRISGPVDLAALRGALDAVARRHP
Mvan_3845|M.vanbaalenii_PYR-1 LTEGQLRMWFVHNADPSGALLNVCLSYRLSGEIDVARLHDAVGAVARRHR
MSMEG_4511|M.smegmatis_MC2_155 LSDGQRRMWFVQGFDPSGVLLNVSLSYRLTGDIDAERMQAAVEAVARRHP
Mflv_2696|M.gilvum_PYR-GCK FTDGQKRMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVARRHP
MAV_2013|M.avium_104 MSVGQHRMWFVQSVDPDSALLNICVSYRLTGGVDTGRLHRAVDAVAARHP
MMAR_3691|M.marinum_M LSDGQRRMWFLQTMDPDDVTLNICVAYRLAGLVDEDRLHTAVNDVVARHA
MUL_3634|M.ulcerans_Agy99 LSDGQRRMWFLQTMDPDDVTLNICVAYRLTGLVDEDRLHTAVNDVVARHA
MAB_2122|M.abscessus_ATCC_1997 LAPGQRRMWFMQTKDPADTSLNICVAHRMRGALDQTRLRDAVAAVIRRHD
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 ILRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLR
Rv2380c|M.tuberculosis_H37Rv ILRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLR
TH_3141|M.thermoresistible__bu VLRTTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQARRLR
Mvan_3845|M.vanbaalenii_PYR-1 VLRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ERARGLR
MSMEG_4511|M.smegmatis_MC2_155 ILRTTF-----HADENGEPRAEVHDDLTPSWTTHDLSEKS---ERARKLR
Mflv_2696|M.gilvum_PYR-GCK VLRTTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EHARRLR
MAV_2013|M.avium_104 VLHTTY-----DTTDEGDPRPVLRADLRPEWAEHDLSGLT---EQARRLR
MMAR_3691|M.marinum_M ILRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHERQ
MUL_3634|M.ulcerans_Agy99 ILRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHEQQ
MAB_2122|M.abscessus_ATCC_1997 VLRTVY-----GVDSAGEPYQLFVEEFEVPWTAVDLTDLT---GDAQDRQ
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 LEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWR
Rv2380c|M.tuberculosis_H37Rv LEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWR
TH_3141|M.thermoresistible__bu LEVLAQREFTAPFDLSVDSPLRITMIRTGADEHIMLLVAHHIAWDDGSWE
Mvan_3845|M.vanbaalenii_PYR-1 LEVLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWDDASWE
MSMEG_4511|M.smegmatis_MC2_155 LEVLAQREFGTPFDLGTESPLRLTLIRTGPAEHVLLLVAHHIAWDDGSWR
Mflv_2696|M.gilvum_PYR-GCK LEVLAQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWR
MAV_2013|M.avium_104 LDVLAQRDFRRPFDLSKDSPLRVTAARLADDELMLLITAHHIAWDDGSWA
MMAR_3691|M.marinum_M IESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWE
MUL_3634|M.ulcerans_Agy99 IESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWE
MAB_2122|M.abscessus_ATCC_1997 VRALADSEFGRPFDLAADRPLRVTLLRLGAEDFVVLLVVHHICWDDNSWE
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 VFFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPP
Rv2380c|M.tuberculosis_H37Rv VFFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPP
TH_3141|M.thermoresistible__bu VFFDDLTRAYTGVDL-GEELAPQLPP----GPRDPDADLAYWREVLADPP
Mvan_3845|M.vanbaalenii_PYR-1 VFFDDLTGAY----V-GEKLRPARRPVVAAGGSD-EDDVAYWRAVMADPP
MSMEG_4511|M.smegmatis_MC2_155 VFFTDLTRAYS-----GEQL-PETPRVGAAAPDTTDEDLAYWREVMANPP
Mflv_2696|M.gilvum_PYR-GCK VFFADLTRAYT-----GAELGPTPAP--VVEPPTSDEDLRFWRSAMTDLP
MAV_2013|M.avium_104 PFFADLTRAYTAPG--DFDATPVVPDLSADPTAIRREDLDYWRPLMADLP
MMAR_3691|M.marinum_M VFFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLP
MUL_3634|M.ulcerans_Agy99 VFFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLP
MAB_2122|M.abscessus_ATCC_1997 VFFAELSEYYHGRPVQGEAPQFMVVS--ADTEPSSDADLTYWRRALTPLP
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 EPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLL
Rv2380c|M.tuberculosis_H37Rv EPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLL
TH_3141|M.thermoresistible__bu EPLELPGPHGSAVPSGWRSARDSVTLGADTARRVVELAQETGCTPYAVLL
Mvan_3845|M.vanbaalenii_PYR-1 EPLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALADEVGATPYAVLL
MSMEG_4511|M.smegmatis_MC2_155 EPLELPGPMGSVVPTGFRSQRSTVRLSAETVEKVTVLARETGATPYMVLL
Mflv_2696|M.gilvum_PYR-GCK EPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAAREAGATPYMVML
MAV_2013|M.avium_104 EPLELPGPNGSVVPSTWRAQRAFAELPAEIVDRAAALARETGATPYMVLM
MMAR_3691|M.marinum_M EPPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEDFARKCSASPFMVLL
MUL_3634|M.ulcerans_Agy99 EPPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEEFARKCSASPFMVLL
MAB_2122|M.abscessus_ATCC_1997 DPLELPGAAS--TYSSRAARRLAVPMPAETAARIEEFAREHSATPFMVLL
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 AAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAM
Rv2380c|M.tuberculosis_H37Rv AAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAM
TH_3141|M.thermoresistible__bu AVFGTLIFRYTHADDFLVATPVLNRDSGAEQRIGYYGNTVAMRLRPNAAM
Mvan_3845|M.vanbaalenii_PYR-1 AVFGVLIHRYSHVDDFLVATPVLNRNGDTDDVIGYFGNTVAMRLRPHPAM
MSMEG_4511|M.smegmatis_MC2_155 AAFGALIRRYTHTDDFLVATPVLNR--DTEDTIGYHGNTVAMRMRPRSDA
Mflv_2696|M.gilvum_PYR-GCK AAFGALLHRYTHADDVLIASPVLLRGPDSEDVIGYHGNSAVMRLRPQPMQ
MAV_2013|M.avium_104 AAFAALVHRYTGSTDFLVAAPVLNRGAATENVIGYYGNTVVIRLRPQSHQ
MMAR_3691|M.marinum_M AAYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQD
MUL_3634|M.ulcerans_Agy99 AAYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQD
MAB_2122|M.abscessus_ATCC_1997 AAFGVLVHRYTGSRDFVTAIPVAERKSNAEKAIGYFGNTLLLRTVVNPDD
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 SFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSF
Rv2380c|M.tuberculosis_H37Rv SFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSF
TH_3141|M.thermoresistible__bu SFRDMLAQSRDTALGAFAHQGINLDRVVRELNPDR---RHGTERMTRVSF
Mvan_3845|M.vanbaalenii_PYR-1 TFRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDR---RHGAERMTRVSF
MSMEG_4511|M.smegmatis_MC2_155 GFRDLVLQTRDVALGAFAHQRVNLDRVVRELNPDR---RHGAERMTRVSF
Mflv_2696|M.gilvum_PYR-GCK TFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDR---RHGAERMTRVSF
MAV_2013|M.avium_104 SFRELLAQTRDGAVGAFAHSRADLDWLVRESNPDR---RHGADRMTRVSF
MMAR_3691|M.marinum_M TFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGF
MUL_3634|M.ulcerans_Agy99 TFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGF
MAB_2122|M.abscessus_ATCC_1997 SFASHVAAVREVCLDAFGHQNVGIDEVVREVNPSRSIGHDGMDELVRLGF
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 GFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDR-----AGVLVE
Rv2380c|M.tuberculosis_H37Rv GFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDR-----AGVLVE
TH_3141|M.thermoresistible__bu GFRGPDRFGFTPPGVRCERAELRSHLTQLPLGVMIEFDPDP-ADPGATVE
Mvan_3845|M.vanbaalenii_PYR-1 GFRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDP-----DEVVVE
MSMEG_4511|M.smegmatis_MC2_155 GFREPDGGGFCPAGVRCERAELRGNHTQLPLGFMVEWEA-----TGATVE
Mflv_2696|M.gilvum_PYR-GCK GFREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHE-----SGAVVE
MAV_2013|M.avium_104 GQREPDGAGFCPPGVRCERGDLRGHFNQLPLSLMVELNRTPDGSGGGLVE
MMAR_3691|M.marinum_M NMR-KSAGGLALDGVVVRQLGLGAVAAHLPLSLTIALDP-----DDVSVE
MUL_3634|M.ulcerans_Agy99 NMR-KSAGGLALDGVVVRQLGLGAIAAHLPLSLTIALDP-----DDVSVE
MAB_2122|M.abscessus_ATCC_1997 SMR-KDASGYRLEGVDVTQLDLAAVSAQLPLSLAIATES-----SGTIVE
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 AEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLR
Rv2380c|M.tuberculosis_H37Rv AEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLR
TH_3141|M.thermoresistible__bu IEHLVEVIEPALGRQLLRHFVVLLEDALRRPDTPLSRLRLMDDADLAWLR
Mvan_3845|M.vanbaalenii_PYR-1 LEHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSGLQLMGDDDLEWLR
MSMEG_4511|M.smegmatis_MC2_155 AEHLTEVLDAALAEQMLRHFTVLLDNALADPDRALWRLDLFTAEDTAWLT
Mflv_2696|M.gilvum_PYR-GCK AEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELMDGDDAEWLR
MAV_2013|M.avium_104 AEYLVEVLDQQLVEQMLRHYRTLLDSLLSDPDATLSACALMSDADAEWLR
MMAR_3691|M.marinum_M FEYQQQLS-SVLVDQMLVHYLQLVDKALAEPERPLSSLDILGAGERDSVL
MUL_3634|M.ulcerans_Agy99 FEYQQQLS-SVLVDQMLAHYLQLVDKALAEPERPLSSLDILGAGERDSVL
MAB_2122|M.abscessus_ATCC_1997 FEYQTDVLPQWLVGQLLVHYQRLLADGLSRPEETLARLELFDAEEHSALL
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 EVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEAS
Rv2380c|M.tuberculosis_H37Rv EVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEAS
TH_3141|M.thermoresistible__bu DVSRGDRFDTPARTLPDLIESQVRQT--PDAVAVVYEGRHYSYRELNEAA
Mvan_3845|M.vanbaalenii_PYR-1 AVSVGPTFDTPPATITDLIEAQVRRS--PDGTAVVYEGRHYTYREINEAA
MSMEG_4511|M.smegmatis_MC2_155 RMATGEAFDTPAATLTDLVTQQAERT--PDATAVVYEGRHFTYREINESA
Mflv_2696|M.gilvum_PYR-GCK RVSHGPEFDVPAATIGELIEARTDLT--PDTVAVVYEGRRYTYREINESA
MAV_2013|M.avium_104 AVSTGEQFITPAATLSELVSRRAART--PDAVAVVYEGRTYTYRDIEEES
MMAR_3691|M.marinum_M AQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRRA
MUL_3634|M.ulcerans_Agy99 AQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRRA
MAB_2122|M.abscessus_ATCC_1997 DQSHGVLTRPSAATLVDLLDAAARAT--PEALAVVSDDVELTYELLQQRS
MLBr_01051|M.leprae_Br4923 ------------MLLASLNPSVVTAT--DIADAVCVDGVVLSRSGLVGAA
: .* . : *: : : : :
Mb2401c|M.bovis_AF2122/97 NRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYP
Rv2380c|M.tuberculosis_H37Rv NRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYP
TH_3141|M.thermoresistible__bu NRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVLKAGAVYLPIDPTYP
Mvan_3845|M.vanbaalenii_PYR-1 NRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKAGAVYVPIDPAYP
MSMEG_4511|M.smegmatis_MC2_155 NRLAHWLIGQGIGTEDRVAVLLEKSPELVITALGIVKAGAVYLPVDPTYP
Mflv_2696|M.gilvum_PYR-GCK NRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGAVYLPVDPSYP
MAV_2013|M.avium_104 NRVAHWLIERGVGTEDRVAVLLDKSPELVITALGVLKAGGVYLPVDPTYP
MMAR_3691|M.marinum_M NRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAYP
MUL_3634|M.ulcerans_Agy99 NRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAYP
MAB_2122|M.abscessus_ATCC_1997 NRFARWLVAQGAGTEDVIALQMSTSVEFIVAMLGVLKSGAAYMPIDPALP
MLBr_01051|M.leprae_Br4923 T-----SVAERVGGARLVAVLATPTASTVLAITGCLIAGVPVVPVPADIG
. : . * :.: : . ::: . : :* :*: .
Mb2401c|M.bovis_AF2122/97 QDRLDFILADCDAKLVLRT--PVRELAGYRSD-----DPTDADRIRPLRP
Rv2380c|M.tuberculosis_H37Rv QDRLDFILADCDAKLVLRT--PVRELAGYRSD-----DPTDADRIRPLRP
TH_3141|M.thermoresistible__bu DDRLSFILGDCDARLVLRE--PVSDLDGQPTT-----DPTDTDRVRRLLP
Mvan_3845|M.vanbaalenii_PYR-1 QDRLEFILGDCDAKVVVRE--PVTGLDGYRAD-----DPGDNDRRRPVGP
MSMEG_4511|M.smegmatis_MC2_155 EDRLNYILSDSDPKIVLRE--FVTGLDDQPTT-----DPTDAERVRPLRP
Mflv_2696|M.gilvum_PYR-GCK QDRMSFVLSDSDPTLVIRE--PVAGLDGHRTD-----NPTDDVRVRPLRP
MAV_2013|M.avium_104 QDRLNFILGDADAKLVLRE--PVTDLADYPAT-----APT--ELLRPLTP
MMAR_3691|M.marinum_M DERIDYLITDARPQTVIGR--PELDVAERAAADNSDLPLSDSDRLRPLRP
MUL_3634|M.ulcerans_Agy99 DERIDYLITDARPQTVIGR--PELDVAERAAADNSDLPLSDGDRLRPLRP
MAB_2122|M.abscessus_ATCC_1997 EERIEYLIADAKPRIVMRP--QEFRVAEAAATGLGDAPITDADRLRPLLP
MLBr_01051|M.leprae_Br4923 VVERRHMLTDSGAQAWLGPGPSADSAPDGLPHIPVQLDARSWNRYPEPSP
. .:: *. . : . *
Mb2401c|M.bovis_AF2122/97 DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQ-VA
Rv2380c|M.tuberculosis_H37Rv DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQ-VA
TH_3141|M.thermoresistible__bu GNTAYLIYTSGTTGLPKGVPVPHRPVAEYFVWFKGDYQVDANDRLLQ-VA
Mvan_3845|M.vanbaalenii_PYR-1 YNTAYLIYTSGSTGLPKGVPVPHRPVAEYFVWFKGDYRVDAGDRMLQ-VA
MSMEG_4511|M.smegmatis_MC2_155 DNTAYLIYTSGSTGLPKGVPVPHRPIAEYFVWFGGEYDVTNEDRLLQ-VA
Mflv_2696|M.gilvum_PYR-GCK ENAAYLIYTSGSTGQPKGVPVPHRPVAEYFVWFKDEYEISESDRLLQ-VA
MAV_2013|M.avium_104 QNTAYLIYTSGSTGLPKGVPVPHAPIAEYFVWFGDEYRIDETDRLLQ-VA
MMAR_3691|M.marinum_M GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWTMTAEDRWLQ-FS
MUL_3634|M.ulcerans_Agy99 GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWTMTAEDRWLQ-FS
MAB_2122|M.abscessus_ATCC_1997 DNLAYVIYTSGSTGRPKGVAVAHAAIAEHVVSFTAEWSMTADDRMLQ-ST
MLBr_01051|M.leprae_Br4923 DATAMVIYTSGTTGPPKGVLLSRRAIAVDLDALAQAWQWTADDVLVHGLP
* :*****:** **** :.: .:* . : : * :: .
Mb2401c|M.bovis_AF2122/97 SPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFV
Rv2380c|M.tuberculosis_H37Rv SPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFV
TH_3141|M.thermoresistible__bu SPSFDVSIAEIFGTLACGARLVIHRPGGLNDIGYLTALLQDEGITAMHFV
Mvan_3845|M.vanbaalenii_PYR-1 SPSFDISIAEVFGTLACGARLVIHRPGGLNDIGYLTALLRDEGITAMHFV
MSMEG_4511|M.smegmatis_MC2_155 SQSFDVSIGEIFGMLAAGARLVIPKPGGLTDIGYLTDLLRNEGITSMHFV
Mflv_2696|M.gilvum_PYR-GCK SPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAYLTELLQREGITAMHFV
MAV_2013|M.avium_104 SPSFDVSIGEIFGTLIMGARLVIPRPDGLRDIGYLTELLAREGITSMHFV
MMAR_3691|M.marinum_M SVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVTVLHLV
MUL_3634|M.ulcerans_Agy99 SVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVTVLHLV
MAB_2122|M.abscessus_ATCC_1997 SVSFDASLADILCPLSLGAQLVIPKPNPFSDIGYVADLVRRRGVTVLHMV
MLBr_01051|M.leprae_Br4923 LFHVHGLVLGLLGSLRIGNRFVHT--GKPTPTAYAQACSEAGGSLYFGVP
.. : :: * * ::: . .* * : .
Mb2401c|M.bovis_AF2122/97 PSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYG
Rv2380c|M.tuberculosis_H37Rv PSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYG
TH_3141|M.thermoresistible__bu PSLLGLFLSLPGVNQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYG
Mvan_3845|M.vanbaalenii_PYR-1 PSLLGLFLSLPGVNQWRTLQRVPIGGEALPGEVADKFRATFDALLHNFYG
MSMEG_4511|M.smegmatis_MC2_155 PSLLGLFLSLPGVNEWRTLQRVPIGGEALPGEIADKFHATFDSLLHNFYG
Mflv_2696|M.gilvum_PYR-GCK PSLLGLFLSLPGVNQWRTLERVPIGGEALPGELADRFHATFDALLHNFYG
MAV_2013|M.avium_104 PSLLGLFLSLPGVSQWRTLRRVPIGGEALPGEIADKFHATFDASLYNFYG
MMAR_3691|M.marinum_M PSMLSTLLLLPQVQQWRQLRHVPVGGEALPGEVADRFAGYFDAELRNHYG
MUL_3634|M.ulcerans_Agy99 PSMLSTLLLLPQVQQWRQLRHVPVGGEALPGEVADRFAGYFDAELRNHYG
MAB_2122|M.abscessus_ATCC_1997 PSLLGSVLLLPEARELRGLRHVPVGGEALPGEVADKFATMFDAELRNHYG
MLBr_01051|M.leprae_Br4923 TVWSRLVADEAVARALRPARLLVSGSASLPVPVFDRLAHLTGHRPIERYG
. . . . * . : *. .** : *:: . : **
Mb2401c|M.bovis_AF2122/97 PTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTG--VI
Rv2380c|M.tuberculosis_H37Rv PTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTG--VI
TH_3141|M.thermoresistible__bu PTETVINASRYKVEGKQGTRIVPIGRPKINTQLHLLDNALQPVPVG--VI
Mvan_3845|M.vanbaalenii_PYR-1 PTETVINATRFKVEGRQGTRIVPIGKPKINTAIHILDDALQPVPVG--SI
MSMEG_4511|M.smegmatis_MC2_155 PTETVLNCTRYKVEGKQGARTVPIGKPKINTTIHLLDDALQPVPVG--VI
Mflv_2696|M.gilvum_PYR-GCK PTETIINTTRYKVEGTQGSRIVPIGTPKINTTVHLLDDALRPVPVG--AI
MAV_2013|M.avium_104 PTETVVNCTSYPVEGAQGTRVVPIGRPKINTRVYLLDNALQPVPPG--VI
MMAR_3691|M.marinum_M PTEAVVCSTHMVVTGSHGARVVPIGVPNRNVYAYVLDEQLHPVPDQ--VI
MUL_3634|M.ulcerans_Agy99 PTEAVVCSTHMLVTGSHGARVVPIGVPNRNVYAYVLDEQLHPVPDQ--VV
MAB_2122|M.abscessus_ATCC_1997 PTEAVVCSTYMSVRGPQGNSIVPIGRPNQNVYAYVLDQALKLVPAG--VV
MLBr_01051|M.leprae_Br4923 STESLITLSTLADGERRAG---WVGLPLAGVQTRLVDESGGPVPYDGETV
.**::: : :. :* * .. ::*: ** :
Mb2401c|M.bovis_AF2122/97 GEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGD
Rv2380c|M.tuberculosis_H37Rv GEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGD
TH_3141|M.thermoresistible__bu GEIYIGGTHVAHGYHRRPGLTAERFVADPFNPGGRLYRSGDLARRNADGD
Mvan_3845|M.vanbaalenii_PYR-1 GEIYIGGTHVARGYHHRPGLTAERFVADPFTPGARMYRSGDLARRNADGD
MSMEG_4511|M.smegmatis_MC2_155 GEIYIGGTHVAHGYHRRPGMTAERFVADPFNPGGRMYRSGDLARRNADGD
Mflv_2696|M.gilvum_PYR-GCK GEIYIGGGHVARGYHRRPALTAERFVADPFTVGGRLYRSGDLARRNADGD
MAV_2013|M.avium_104 GEIYIAGTHVAHGYHRRPQLTAERFVADPFSRGGRMYRSGDLARRNANGD
MMAR_3691|M.marinum_M GELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLVRRNHCGE
MUL_3634|M.ulcerans_Agy99 GELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLVRRNHCGE
MAB_2122|M.abscessus_ATCC_1997 GELYLGGAQLARGYRARPVLTAERFVADPFGSGGRLYRTGDLVRRNARGE
MLBr_01051|M.leprae_Br4923 GRLQVRSPTMFGGYLNRPEATAEAFDED------GWYRTGDVAVVDSGGM
*.: : . : ** *. **: * * **:**:. : *
Mb2401c|M.bovis_AF2122/97 IEFVGR-ADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKS
Rv2380c|M.tuberculosis_H37Rv IEFVGR-ADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKS
TH_3141|M.thermoresistible__bu IEFVGR-ADEQVKIRGFRIELGDVAAAISVDPSVGQAVVVATDLPNVGRS
Mvan_3845|M.vanbaalenii_PYR-1 IEFVGR-ADEQVKIRGFRIELGDVAAAITVDPSVGQAVVVVSDLPNLGKS
MSMEG_4511|M.smegmatis_MC2_155 IEFVGR-ADEQVKIRGFRIELGEVSAAISVDPSVGQAVVVVSDLPSLGKS
Mflv_2696|M.gilvum_PYR-GCK LEFVGR-ADDQVKIRGFRIELGEVAAAISVDPSVGQAVVLGQDLPGLGMS
MAV_2013|M.avium_104 IEFVGR-ADEQVKIRGFRIELGEIAAAISVDPSVGQAVVLAMDLPQLGKS
MMAR_3691|M.marinum_M LEFVGR-ADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEETEAGPM
MUL_3634|M.ulcerans_Agy99 LEFVGR-ADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEETEAGPM
MAB_2122|M.abscessus_ATCC_1997 LEFVGR-ADEQVKVRGYRIELGEIEAVIGADPRVGHCVATVVDDPQVGSL
MLBr_01051|M.leprae_Br4923 HRIVGRESVDLIKLGGYRIGAGEIEMALLGHPDVREVAVVGLPDEDLGQR
.:*** : : :*: *:** *:: .: .* * . . *
Mb2401c|M.bovis_AF2122/97 LVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIPIT
Rv2380c|M.tuberculosis_H37Rv LVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIPIT
TH_3141|M.thermoresistible__bu LVGYLTPVSG---ESTDSVAVERIRARVAAALPEYMVPAAYVVLDEIPIT
Mvan_3845|M.vanbaalenii_PYR-1 LVAYLTPADG------AGVDVDRIRTRVAAALPEYMTPAAYVVVDEIPIT
MSMEG_4511|M.smegmatis_MC2_155 LVAYITPAAG-----ADHVDIERIRARVTAALPEYMVPAAYVELDEIPIT
Mflv_2696|M.gilvum_PYR-GCK LVGYVTPAAG------EDVDLARVRERVAAALPDYMTPAGYVVLDEIPIT
MAV_2013|M.avium_104 LVGYVTPAQG---AGTETVDVERIRARVAAALPDYMTPAAYVVLDEIPIT
MMAR_3691|M.marinum_M LAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIPMT
MUL_3634|M.ulcerans_Agy99 LAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIPMT
MAB_2122|M.abscessus_ATCC_1997 LAAYVVPAGG-----TREIDLDELRARAQEALPAYMVPTAFAVIPEIPLT
MLBr_01051|M.leprae_Br4923 IVAFVVGAEA--------LDADELINYVAQQLSIHKRPREVRFVDALPRN
:..::. . : .: . :. : * : :* .
Mb2401c|M.bovis_AF2122/97 AHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGR-DRVGADD
Rv2380c|M.tuberculosis_H37Rv AHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGR-DRVGADD
TH_3141|M.thermoresistible__bu THGKIDRAALPEPQIASMIEYREPATDTEREVARLFGDLLGRSERIGADD
Mvan_3845|M.vanbaalenii_PYR-1 AHGKIDRAALPEPEIAPTTEFREPAAGTEAHLAQLFAELLGH-EKVGADD
MSMEG_4511|M.smegmatis_MC2_155 THGKIDRRALPEPEITSTTRFREPSTDTERTVAGLFAELLER-DEVGADD
Mflv_2696|M.gilvum_PYR-GCK AHGKIDRAALPLPEITTATDYREPQTETEQHLAQLFSELLGV-ARVGVDD
MAV_2013|M.avium_104 AHQKIDRAALPQPQIGAGTEYRDPTTPTEHRIAQLFSGLLGH-ERVGVDD
MMAR_3691|M.marinum_M VSGKLDRRALPAPTPIATRRYREPETATERWICSIFAQLFGR-QRVGAED
MUL_3634|M.ulcerans_Agy99 VSGKLDRRALPAPTPIATRRYREPETATERWICSIFAQLFGR-QRVGAED
MAB_2122|M.abscessus_ATCC_1997 TSGKLDKRALPTPDALTERAFRLPVTPTERRMCAIYSHLFGK-ERVGLDD
MLBr_01051|M.leprae_Br4923 AMGKVLKKQLLFEG------------------------------------
. *: : *
Mb2401c|M.bovis_AF2122/97 SFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAG-------
Rv2380c|M.tuberculosis_H37Rv SFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAG-------
TH_3141|M.thermoresistible__bu SFFDLGGHSLLATKLVAAVRSAFGVDIGVQDVFELGTVARLAG-------
Mvan_3845|M.vanbaalenii_PYR-1 SFFDLGGHSLLATKLVAELRAGFGVDVEVRDIFENATIARLAA-------
MSMEG_4511|M.smegmatis_MC2_155 SFFDLGGHSLLATKLVAAVRARCAVDVGVQDVFEHATVSGLAA-------
Mflv_2696|M.gilvum_PYR-GCK SFFELGGHSLLATKLVSAVRSRCGVDMEIREIFELGTVARLAE-------
MAV_2013|M.avium_104 SFFDLGGHSLVATKLVTAIRAECGVEIGIRDVFELATVGLLAE-------
MMAR_3691|M.marinum_M SFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDAPTPAGLAARLVERFR
MUL_3634|M.ulcerans_Agy99 SFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDVPTPAGLAARLVERFR
MAB_2122|M.abscessus_ATCC_1997 SFFELGGHSLLAARLVAQIRAQFGIDLTVRAVFDRPTPAGLAEQLVTYFR
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 -----HIDTLDSDS----------ARPRLTRVDHDGPVRLSSSQMRSWFN
Rv2380c|M.tuberculosis_H37Rv -----HIDTLDSDS----------ARPRLTRVDHDGPVRLSSSQMRSWFN
TH_3141|M.thermoresistible__bu -----RIDELRSGSG-------GPLRPRLTPQHFDGPAPLSSSQLRSWFA
Mvan_3845|M.vanbaalenii_PYR-1 -----HLDTMGRATI-------GTRRPRLVAAPLDGPAPLSSSQLRSWFG
MSMEG_4511|M.smegmatis_MC2_155 -----HIEDLVASGA-------SSGRPAIVAVPHDGPLQMSAAQLRQWFQ
Mflv_2696|M.gilvum_PYR-GCK -----RVDELAAGGS-------APLRPRLLAVPHDGPAPMSAAQLRQWFQ
MAV_2013|M.avium_104 -----RVDQLSSGEL-------TGTRPKLIATAHDEPLPLSASQLRSWFA
MMAR_3691|M.marinum_M NDFELDLDNLAADD---MPLDPKRARPGFVKSARPQRLPLSHSQLAAWFQ
MUL_3634|M.ulcerans_Agy99 NDFELDLDNLAADD---MPLDPKQARPGFVKSARPQWLPLSHSQLAAWFQ
MAB_2122|M.abscessus_ATCC_1997 EEFEIELDELDLDESDEMEAAPQDGRPDLVAAERPERLPLSSSQLSMWFE
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 YRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGG
Rv2380c|M.tuberculosis_H37Rv YRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGG
TH_3141|M.thermoresistible__bu YRVDGPSVVNNIPFAARLHGPVDVDALEAAIGDVIARHEILRTVYREIDG
Mvan_3845|M.vanbaalenii_PYR-1 YRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDVVERHAILRTTYREIDG
MSMEG_4511|M.smegmatis_MC2_155 FRIDGPNPVNNVPFAARLSGPCDVDALIAAVGDVVARHEILRTTYREIDG
Mflv_2696|M.gilvum_PYR-GCK YRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHESLRTTFCEIDG
MAV_2013|M.avium_104 YRMDGPSPVNNIPFAARLTGPWDIDALIAAVGDVVARHEILRTRYVELDG
MMAR_3691|M.marinum_M YRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALRTNFDEHEG
MUL_3634|M.ulcerans_Agy99 YRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALRTNFDEHEG
MAB_2122|M.abscessus_ATCC_1997 CQMEGVTDIGNMWLALRFDGPLQTPALIAALNDVVARHEALRTNIAIHEG
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 VPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAAL
Rv2380c|M.tuberculosis_H37Rv VPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAAL
TH_3141|M.thermoresistible__bu VPYQIVLPTEP-VPVRRADGQGEQWLRAELDAERRHVFDLENERPIRPAI
Mvan_3845|M.vanbaalenii_PYR-1 VPYQIVNPISD-VPVRRARGEGEQWLQAELDRERKHTFDLEEDWPIRAAV
MSMEG_4511|M.smegmatis_MC2_155 APYQIIHPPAP-VPVRQARGDGEDWVQAQLDAERRYCFDLETDWPIRAAV
Mflv_2696|M.gilvum_PYR-GCK VPYQLVNAPDPGFPVRRDSGPDDAWLVGALDDERRRVFDLENQWPIRVAV
MAV_2013|M.avium_104 VPYQVVGPPGVEIPVRREDGPDDPWLQQQLDAERRHCFELDGELPIRVAV
MMAR_3691|M.marinum_M VPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPESGPLLQANL
MUL_3634|M.ulcerans_Agy99 VPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPESGPLLQANL
MAB_2122|M.abscessus_ATCC_1997 APYQIVHPSRELAVPILRSSPEG--LSDTLAELRHHIFGLETESLIRPAI
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 LSTP-----------------------EQTVLSLVVHHIAGDHWSAGVLF
Rv2380c|M.tuberculosis_H37Rv LSTP-----------------------EQTVLSLVVHHIAGDHWSAGVLF
TH_3141|M.thermoresistible__bu LSLRPDAGSPDS------------PAGDVHVLSLVMHHIAGDHWSATVLF
Mvan_3845|M.vanbaalenii_PYR-1 FTVGAVSPASDGGAVSPASDGGAVDPASDHVLSVVIHHIAGDHWSGGVLF
MSMEG_4511|M.smegmatis_MC2_155 LTTA-----------------------EHHVLSLVVHHIAADHWSGTVLF
Mflv_2696|M.gilvum_PYR-GCK LSIP-----------------------GEHALSVVVHHIAADHWSGGVLF
MAV_2013|M.avium_104 LRVAN---------------------AAEHVLSLVVHHIASDHWSAGVLF
MMAR_3691|M.marinum_M LVLG----------------------PDTHVLLLIVHHIVSDHASLEIVF
MUL_3634|M.ulcerans_Agy99 LVLG----------------------PDTHVLLLIVHHIVSDHASLEIVF
MAB_2122|M.abscessus_ATCC_1997 IELS----------------------AQEHVLALVVHHIVVDHASFTVIV
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 TDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG----IVGPQ
Rv2380c|M.tuberculosis_H37Rv TDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG----IVGPQ
TH_3141|M.thermoresistible__bu TDLLTAYRARTAGQEPAWAPLPVQYADFGAWESELLAEETG----IAGPQ
Mvan_3845|M.vanbaalenii_PYR-1 TDLVAAYRARKAGERPTWAPLPVQYTDYGAWQAELLSDDTG----IAGPQ
MSMEG_4511|M.smegmatis_MC2_155 TDLLTAYHARHAGSAVELPPLPVQYADFAAWQAELLAGTDD----TIDEQ
Mflv_2696|M.gilvum_PYR-GCK TELLTAYRARRAGEAPTWAPLPVQYADYAAWQSALLADDSG----IVAAQ
MAV_2013|M.avium_104 ADVMTAYRARRGGEAPSWAPLRVQYADYAAWQRTFLGDAGGQESAVAGAQ
MMAR_3691|M.marinum_M DDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN------WGQTE
MUL_3634|M.ulcerans_Agy99 DDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN------WGQTE
MAB_2122|M.abscessus_ATCC_1997 DDLIAAYRARLEGQAPQWDPQPVQYADYVLWQRDAFAPDSE----FGQAE
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 RDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVS
Rv2380c|M.tuberculosis_H37Rv RDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVS
TH_3141|M.thermoresistible__bu REYWTRQLAGLPEETGLRPDFPRPPVPSGLAEAVEFTIDAAVREKLAGLC
Mvan_3845|M.vanbaalenii_PYR-1 REYWIRQLADAPVESGLPLEFSRPRLPSGKGDAVEFTIDGQVRRQITELC
MSMEG_4511|M.smegmatis_MC2_155 RRYWTTQLAGLPEENGLYPDFPRPPVPTGDGAALDFSIDADTRARLIALT
Mflv_2696|M.gilvum_PYR-GCK RRYWTQQLEGLSAETGLQPDLVRPSVPSGAADAVEFTLDAAIREKLVTLS
MAV_2013|M.avium_104 REYWTRQLAGLPEDTGLRPDFPRQPVPSGDGESVDFHIDAATRAKLADVC
MMAR_3691|M.marinum_M LDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAARRAALTQLA
MUL_3634|M.ulcerans_Agy99 LDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAARRSALTQLA
MAB_2122|M.abscessus_ATCC_1997 VNFWRQQLAGVPTEIAVAHDRARPQILGKRGEVAKFVMEPERRQALTRMA
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 RDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFI
Rv2380c|M.tuberculosis_H37Rv RDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFI
TH_3141|M.thermoresistible__bu RDLGITEFMALQAAVAVVLHKAGSGSDIPLGTPVAGRSEPELDQLVGFFI
Mvan_3845|M.vanbaalenii_PYR-1 RELGITEFMLLQAAVAVTLAKVGGGLDIPLGTPVAGRSEAELEQLVGFFV
MSMEG_4511|M.smegmatis_MC2_155 RELGVTEFMLLQAAVAIALHKSGQGTDIPLGTPVAGRTAPELDALIGFFI
Mflv_2696|M.gilvum_PYR-GCK REVGATEFMLLQAAVAVTLYKAGEGPDIPLGTPVAGRTESELDQLIGFFI
MAV_2013|M.avium_104 RELGITEFMLLQTAVAVVLHKAGGGVDIPLGTPVAGRTEAELDQLIGFFV
MMAR_3691|M.marinum_M ERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPATAQLVGLFA
MUL_3634|M.ulcerans_Agy99 ERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPATAQLVGLFA
MAB_2122|M.abscessus_ATCC_1997 EQRGVTEFMVYQAALAVVLHRLGGGTDIVIGSPVAARVHPHVAKLVGLFA
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 NIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSL
Rv2380c|M.tuberculosis_H37Rv NIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSL
TH_3141|M.thermoresistible__bu NILVLRNDLSGNPSLREVCRRAREMALAAYAHQDLPFDQVVDAVSPVRTL
Mvan_3845|M.vanbaalenii_PYR-1 NFVVLRNDLRGNPTLREVLIRAREMALSAYSNQDVPFEQVVEAVNPPRTL
MSMEG_4511|M.smegmatis_MC2_155 NIVVLRNDLSGNPSLREVLRRSREMALAAYQHQDLPFDRVVDAVSPVRSL
Mflv_2696|M.gilvum_PYR-GCK NILVLRNDLRDNPSLRDVGFRSREMALAAYAHQDLPFDQVVDAVSPVRSL
MAV_2013|M.avium_104 NILVLRNDLDGNPTLRELLKRARETALAAYAHQDLPFDRVVDSVSPVRSL
MMAR_3691|M.marinum_M NVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVEALNPPRAL
MUL_3634|M.ulcerans_Agy99 NVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVEALNPPRAL
MAB_2122|M.abscessus_ATCC_1997 NMVALRNDLSGDPSLRSVLERSRDATLNAHAHQELPIEKLVEAVNPVRSL
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 SRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPTFDAAQADL
Rv2380c|M.tuberculosis_H37Rv SRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPTFDAAQADL
TH_3141|M.thermoresistible__bu ARNPLFSVVVHVREQLPENRVIDHGPDG----DTTVTVLEPPFDAAHADL
Mvan_3845|M.vanbaalenii_PYR-1 ARNPLFQVVVHVREQLPQRQMIDT--------DTEFTALEPTFDIAQADL
MSMEG_4511|M.smegmatis_MC2_155 SRNPLFGVVVHVRDDLPADQVIDDGGNG----ETRFTALEPTFDVAHADL
Mflv_2696|M.gilvum_PYR-GCK SRNPLFGVVVHVREELPQDRVIATGSDG----ETTFTALEPTFDMAHADL
MAV_2013|M.avium_104 SRNPLFQVVVHVRDHLSATRVIETAPVGGDGQDTVCTSLDPVFDMAHADL
MMAR_3691|M.marinum_M SRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVNFEVALLFL
MUL_3634|M.ulcerans_Agy99 SRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVNFEVALLFL
MAB_2122|M.abscessus_ATCC_1997 SWNPLFQTMVNFRGADWGTAARDVTVSG----ETTVVPLPMEVDVSYLDL
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 SVNFFA-------CGD--EYRGHVIYRTELYERATAQRFADWLVRVVEAF
Rv2380c|M.tuberculosis_H37Rv SVNFFA-------CGD--EYRGHVIYRTELYERATAQRFADWLVRVVEAF
TH_3141|M.thermoresistible__bu SLNFFA-------AEDGGGYRGHVIYRPELYSRDTAQRFADWLGRVVTAF
Mvan_3845|M.vanbaalenii_PYR-1 SLNFLA-------DGT--GYRGYLIYRPELYARRTIERLGRWLPRVVAAF
MSMEG_4511|M.smegmatis_MC2_155 SLNFFAQNGNGGRAGEPAGYKGTVIYRTELYEPATARRLIGWLHRIIDAF
Mflv_2696|M.gilvum_PYR-GCK SVNFFA-------GGN--GYRGHVIYRTELYTRATAERFAGWLSAVITAF
MAV_2013|M.avium_104 SVNFFG-----TDGAGDIGYNCHLIFRTDLYRRTTIERLAGWLVRAVTAF
MMAR_3691|M.marinum_M AIGMSV--------TPSGELDVQVIANADLYEPATVALIADALDAALAAF
MUL_3634|M.ulcerans_Agy99 AIGMSV--------TPSGELDVQVIANADLYEPATVALIADALDAALAAF
MAB_2122|M.abscessus_ATCC_1997 NFALNV--------TPSGGLDVSVVANADLYDHETTRMIAQALDTAFDAF
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 ADRPDQPLREVEMVSAQARRRILDRSNAGAGT------------------
Rv2380c|M.tuberculosis_H37Rv ADRPDQPLREVEMVSAQARRRILDRSNAGAGT------------------
TH_3141|M.thermoresistible__bu AERPDITLRELEIGAPGERRRILEEWGGGT--------------------
Mvan_3845|M.vanbaalenii_PYR-1 VDTPDRALGDVDIVSAEERQRVSQEWSTGAR-------------------
MSMEG_4511|M.smegmatis_MC2_155 ATDADTTLRDIAVIDADERTLLIEDWSRRAVPPA----------------
Mflv_2696|M.gilvum_PYR-GCK ADDPERHVDDVVIAEPVRPGDGAEA-------------------------
MAV_2013|M.avium_104 ADDLDQTLRDVALIDAGEQQRILRQWSRGAQPPRDRPRTIPELLQASRSL
MMAR_3691|M.marinum_M ATTPDLPLSAVQLLPSADLAK-----------------------------
MUL_3634|M.ulcerans_Agy99 ATTPDLPLSAVQLLPRADLAK-----------------------------
MAB_2122|M.abscessus_ATCC_1997 VNNQESRVSEIVLLPADAMAQ-----------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 GADRIAVRCGAEHIDYPALHRRSDNLAALLVDRGVGPGTLVGLSTRRSIE
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 LVVALVAIMKAGAGYFPVDPGYPSARKQFMLDDVRPPVVVATVEAVDTMP
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 GLPGVELLSLDDPQVRALVDRDDVDPRAGRLRPPHPDDPMYLVFTSGSTG
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 KPKGAVGTHRSMAARLDWQLRHYPPRTDDVRLAQASITFLEGGMEMLAGL
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 AAGATMILADDAEHRDPEALGELMHRHSVAQVTAVPSLVSALLDSRPDAV
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 RSLSRLVCGGEPVSTSLLQRLVSVCDEADGGGPELLNNIGSTETSGAVSR
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 ----------------ARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLA
Rv2380c|M.tuberculosis_H37Rv ----------------ARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLA
TH_3141|M.thermoresistible__bu ------------------VYVLDETLQPVPVGVVGDVYTAGPALAAAHWT
Mvan_3845|M.vanbaalenii_PYR-1 ------------------VQVLDADLAPAPVGVFGDLYLSGG--------
MSMEG_4511|M.smegmatis_MC2_155 ---------LPQTEGATNVYVLDEWLEPVAIGVIGDVYYAGGAVDASAEA
Mflv_2696|M.gilvum_PYR-GCK -------------------VLLDGAGHPVPVGVVADVHYAGAPDRRGDRA
MAV_2013|M.avium_104 GPLSPPNPLVGKPVPGAQAYLLDDGLRPVPVGVVGELYYAGDQLARGYWK
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 RPSETA-------------TRFVADPFAAQPGSRLYRNGER---------
Rv2380c|M.tuberculosis_H37Rv RPSETA-------------TRFVADPFAAQPGSRLYRNGER---------
TH_3141|M.thermoresistible__bu RAGVTA-------------TRLVADPVGNRPGARLYRTGDR---------
Mvan_3845|M.vanbaalenii_PYR-1 -------------------------PFAQR-----HRTGDR---------
MSMEG_4511|M.smegmatis_MC2_155 ANGVAA-------------QRFVPNPFGAG---RLYRTGDR---------
Mflv_2696|M.gilvum_PYR-GCK RWTEDGRLQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYVVP
MAV_2013|M.avium_104 RPGLTA-------------ARFVANPFGAEPGSRLYRSGDL---------
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 -------GVWKADGQLELL-------------AEIERLPTAQAAP-----
Rv2380c|M.tuberculosis_H37Rv -------GVWKADGQLELL-------------AEIERLPTAQAAP-----
TH_3141|M.thermoresistible__bu -------ARWIADGVLEFVD------------AQPPTIPAVRPDSG----
Mvan_3845|M.vanbaalenii_PYR-1 -------ARWDDDGRLEIA-------------ARAPGATVVEVAPP----
MSMEG_4511|M.smegmatis_MC2_155 -------ARWTPDGRLEPVT------------AGEPRLQAALEAVDGVAA
Mflv_2696|M.gilvum_PYR-GCK AEPVDDPASFAETVRAAVAP------------ESAPTSITVLDALPATR-
MAV_2013|M.avium_104 -------ARWTEDGQLEFVGRSDHQVQVRGFRVELAEVEAALAGADGVAA
MMAR_3691|M.marinum_M --------------------------------LLAPPLPAGPAASP----
MUL_3634|M.ulcerans_Agy99 --------------------------------LLAPPLPAGPAASQ----
MAB_2122|M.abscessus_ATCC_1997 --------------------------------LMAPPAAAVEPVTT----
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3141|M.thermoresistible__bu --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155 AATRYWENRSAPLLAAYVVADAAHAADPQFAEQVRTALPDEFAGAA----
Mflv_2696|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2013|M.avium_104 AAARTWEVHGGTSLAGYVVPQRPIADEAEKAAFAAQVRAEIAATLPGYMM
MMAR_3691|M.marinum_M --------------------------------------------------
MUL_3634|M.ulcerans_Agy99 --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 -------------------------------VPAEPADTETERALAAILA
Rv2380c|M.tuberculosis_H37Rv -------------------------------VPAEPADTETERALAAILA
TH_3141|M.thermoresistible__bu ------------------------------QRPGGPPATDTERALATLLA
Mvan_3845|M.vanbaalenii_PYR-1 ------------------------------AVEFEEPRTDSERALAALLS
MSMEG_4511|M.smegmatis_MC2_155 ---------ITVVDDLTPAALTRPRVSATASGPFEAPATPTERAVAAMLV
Mflv_2696|M.gilvum_PYR-GCK ----------------------RALPAPRVGGPSEPARTDTEKALVGMLA
MAV_2013|M.avium_104 PSSLTVLDALPKTESGKLNRPGLPRPAVSTGGRTEPARTDTERALANVFA
MMAR_3691|M.marinum_M --------------------------------PVAAGSAETERRLTAMLE
MUL_3634|M.ulcerans_Agy99 --------------------------------PVAAGSAETERRLTAMLE
MAB_2122|M.abscessus_ATCC_1997 --------------------------------PSVEGSEETKLVLISILE
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 DVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVFEH
Rv2380c|M.tuberculosis_H37Rv DVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVFEH
TH_3141|M.thermoresistible__bu EVLDTEVTG----RDDDFFSLGGDSILAVQLAARARDTGLKLTARMVFEH
Mvan_3845|M.vanbaalenii_PYR-1 ELLATEEVG----RHDDFFGLGGDSVLAVQLAARARDTGLDLTARMVFEH
MSMEG_4511|M.smegmatis_MC2_155 ELLGVTQVG----RHDDFFTLGGDSILAVQLAARARDAGVAMTARMVFEH
Mflv_2696|M.gilvum_PYR-GCK DVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAKQAGLRLSARMVFEH
MAV_2013|M.avium_104 ELLSTPEVG----RFDDFFALGGDSILSVQLASRARAAGLPVSPRMIFEN
MMAR_3691|M.marinum_M ELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVFEH
MUL_3634|M.ulcerans_Agy99 ELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVFEH
MAB_2122|M.abscessus_ATCC_1997 ELLEISDVD----PEDNFFALGGDSVISIQWSTRAAERGLAMTPQMVFEC
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 PVLCELAAAVDAKPHVEAEPDDKH--------------------------
Rv2380c|M.tuberculosis_H37Rv PVLCELAAAVDAKPHVEAEPDDKH--------------------------
TH_3141|M.thermoresistible__bu PTLHELAAAVEAREAVEARETAEAGGAEAGGAESGGGADGAERGAAAGDS
Mvan_3845|M.vanbaalenii_PYR-1 PRLAELAAALDSGAGAAAEQPDTH--------------------------
MSMEG_4511|M.smegmatis_MC2_155 PVLSELAAAIDAAGEGSAAQDVHH--------------------------
Mflv_2696|M.gilvum_PYR-GCK PVVHDLAVALDTAKTPEVADVRHD--------------------------
MAV_2013|M.avium_104 PTVQQLAAALDALGDNDSDGRLDDQ-------------------------
MMAR_3691|M.marinum_M MTIAELAAAVDAANGEPVVEAD----------------------------
MUL_3634|M.ulcerans_Agy99 MTIAELAAAVDAANGEPVVEAD----------------------------
MAB_2122|M.abscessus_ATCC_1997 ATIAQLAGAVDAADR-VVTEGDSHL-------------------------
MLBr_01051|M.leprae_Br4923 --------------------------------------------------
Mb2401c|M.bovis_AF2122/97 ------HAPMSTSGLSPDELSALTASWDQWP----
Rv2380c|M.tuberculosis_H37Rv ------HAPMSTSGLSPDELSALTASWDQWP----
TH_3141|M.thermoresistible__bu GNGAASHAPMSTSGLSAEQLSALTASWNPAGEDAP
Mvan_3845|M.vanbaalenii_PYR-1 ------HAPMSVSGLSEDELAALTASWGTGE----
MSMEG_4511|M.smegmatis_MC2_155 -------APMEASGLSSDELAALTAAWGQSQDGKR
Mflv_2696|M.gilvum_PYR-GCK --------PMSASGLTPEELAMVATSWAAEQDGSP
MAV_2013|M.avium_104 -PADTRFEPMSTSGLSASDLAAVTQLWSSSREGTA
MMAR_3691|M.marinum_M PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MUL_3634|M.ulcerans_Agy99 PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MAB_2122|M.abscessus_ATCC_1997 VTPPVQSAPMSASGLSADALAELTASWQAQS----
MLBr_01051|M.leprae_Br4923 -----------------------------------