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SPITREERLERRIQDLYANDPQFAAAKPVTAITAAIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTD AGTGHTTLRLLPHFETISYGELWDRISALADVLSTEQTVKPSDRVCLLGFNSVDYATIDMTLARLGAVAV PLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQTATRVLVFDHHRQVDAHRAAVESARERLA GSAVVETLAEAIARGDVPRGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRTWFE GGYEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVVKSDLSTLFEDLALVRPTELTFVPRVWDMVFDEF QSEVDRRLVDGADRVALEAQVKAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELLDMHLVEGYGSTEAG MILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYYQRAEVTADVFDADGFYRTGD IMAEVGPEQFVYLDRRNNVLKLSQGEFVTVSKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDA VPVEELKARLGDSLQEVAKAAGLQSYEIPRDFIIETTPWTLQNGLLTGIRKLARPQLKKHYGELLEQIYT DLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGSASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDI DVPVGVIVSPANDLQALADYVEAARKPGSSRPTFASVHGASNEQVTEVHAGDLSLDKFIDAATLAEAPRL PAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRAKSDTEARARLEKTFDSGAPELLAHYR ALAGDHLEVLAGDKGEADLGLDRQTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTS KIKPYSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAGEVLLREAHVLCGLPVAVF RCDMILADTTWAGQLNVPDMFTRMILSLAATGIAPGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ SQDGFHTYHVMNPYDDGIGLDEFVDWLNESGCPIQRIADYGDWLQRFETALRALPDRQRHSSLLPLLHNY RQPERPVRGSIAPTDRFRAAVQEAKIGPDKDIPHVGAPIIVKYVSDLRLLGLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1722 | - | - | 100% (1174) | fatty-acid-CoA ligase FadD9 |
| M. ulcerans Agy99 | MUL_3542 | fadD15 | 1e-26 | 25.83% (569) | long-chain-fatty-acid-CoA ligase FadD15 |
| M. ulcerans Agy99 | MUL_4349 | fadD15_1 | 3e-22 | 23.19% (565) | long-chain-fatty-acid-CoA ligase FadD15_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2621 | fadD9 | 0.0 | 75.47% (1174) | fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_2962 | - | 7e-31 | 25.09% (570) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2590 | fadD9 | 0.0 | 75.55% (1174) | fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_00484 | fadD9 | 0.0 | 68.39% (1183) | putative acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2962 | - | 0.0 | 57.09% (1184) | fatty-acid-CoA ligase FadD |
| M. marinum M | MMAR_2117 | fadD9 | 0.0 | 99.23% (1174) | fatty-acid-CoA ligase FadD9 |
| M. avium 104 | MAV_3471 | - | 0.0 | 72.15% (1185) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2956 | - | 0.0 | 70.18% (1177) | NAD dependent epimerase/dehydratase family protein |
| M. thermoresistible (build 8) | TH_1879 | fadD9 | 1e-161 | 56.24% (553) | PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-CoA |
| M. vanbaalenii PYR-1 | Mvan_2578 | - | 0.0 | 68.73% (1180) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1722|M.ulcerans_Agy99 --------------MSPITREER-LERRIQDLYANDPQFAAAKPVTAITA
MMAR_2117|M.marinum_M --------------MSPITREER-LERRIQDLYANDPQFAAAKPATAITA
Mb2621|M.bovis_AF2122/97 --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
Rv2590|M.tuberculosis_H37Rv --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
MLBr_00484|M.leprae_Br4923 MWRQQSISHRKESVMSTITKQEKQLARRVDDLTANDPQFAAAKPDPAVAA
MAV_3471|M.avium_104 --------------MSTATHDER-LDRRVHELIATDPQFAAAQPDPAITA
MSMEG_2956|M.smegmatis_MC2_155 --------------MTIETREDR-FNRRIDHLFETDPQFAAARPDEAISA
Mvan_2578|M.vanbaalenii_PYR-1 --------------MSTDTREDR-LARRIADLYATDPQFAAAAPDDAISH
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 -----------MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAE
Mflv_2962|M.gilvum_PYR-GCK ---------------------------MTAREFTVPAPFTVEERDNIVGA
MUL_1722|M.ulcerans_Agy99 AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MMAR_2117|M.marinum_M AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
Mb2621|M.bovis_AF2122/97 AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
Rv2590|M.tuberculosis_H37Rv AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
MLBr_00484|M.leprae_Br4923 ALAQPGLRLPQIIQTALDGYAERPALGQRVAEFTKDPKTGRTSMELLPSF
MAV_3471|M.avium_104 ALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVTDAKTGRTSAQLLPRF
MSMEG_2956|M.smegmatis_MC2_155 AAADPELRLPAAVKQILAGYADRPALGKRAVEFVTD-EEGRTTAKLLPRF
Mvan_2578|M.vanbaalenii_PYR-1 AIDQPGTHLPVIVQTVLDGYAERPALGQRAVRFVTDPATGRTTTELLPRF
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 QVLRPGLHLSEAIAALMTGYAERPALGERARELVTD-QDGRTTLRLLPRF
Mflv_2962|M.gilvum_PYR-GCK VFTHERDDPDHVIFQRLVDG----------------------------KW
MUL_1722|M.ulcerans_Agy99 ETISYGELWDRISALADVLSTEQ--TVKPSDRVCLLGFNSVDYATIDMTL
MMAR_2117|M.marinum_M ETISYGELWDRISALADVLSTEQ--TVKPGDRVCLLGFNSVDYATIDMTL
Mb2621|M.bovis_AF2122/97 ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
Rv2590|M.tuberculosis_H37Rv ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
MLBr_00484|M.leprae_Br4923 ETITYRQLGDRVGALARAWRHD---LLHAGYRVCVLGFNSVDYAIIDMAL
MAV_3471|M.avium_104 ETITYGEVAQRVSALGRALSDD---AVHPGDRVCVLGFNSVDYATIDMAL
MSMEG_2956|M.smegmatis_MC2_155 DTITYRQLAGRIQAVTNAWHNH---PVNAGDRVAILGFTSVDYTTIDIAL
Mvan_2578|M.vanbaalenii_PYR-1 ETITYAELSRRIHAVTAALT-----DVHPGDRVAVLGFTSIDYTTVDMAL
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 DTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAI
Mflv_2962|M.gilvum_PYR-GCK IDVTARQAAGQIRSAARGLIAEG---VQAGDRVALLSATRYEWPILDFAI
MUL_1722|M.ulcerans_Agy99 ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MMAR_2117|M.marinum_M ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
Mb2621|M.bovis_AF2122/97 IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
Rv2590|M.tuberculosis_H37Rv IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
MLBr_00484|M.leprae_Br4923 GVIGAVAVPLQTSAAITQLQSIVTETEPSMIATSVNQLPDTVELIL-SGQ
MAV_3471|M.avium_104 GAIGAVSVPLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQ
MSMEG_2956|M.smegmatis_MC2_155 LELGAVSVPLQTSAPVAQLQPIVAETEPKVIASSVDFLADAVALVESGPA
Mvan_2578|M.vanbaalenii_PYR-1 AMLGAVAVPLQTSAPATTVRPIVAETEPVVIASSVDALTDAVGLALDAPT
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MILGGVAVPLQTSAPASQWTTILAEAEPNTLAVSIELIGAAMESVRATPS
Mflv_2962|M.gilvum_PYR-GCK LSIGAVTVPIYETSSAEQVQFVLADSGAVAAIAETDAHAAHIEAQRDTLP
MUL_1722|M.ulcerans_Agy99 A-TRVLVFDHHRQVDAHRAAVESARERLAGS---AVVETLAEAIARGDVP
MMAR_2117|M.marinum_M A-TRVLVFDHHRQVDAHRAAVESARERLAGS---AVVETLAEAIARGDVP
Mb2621|M.bovis_AF2122/97 P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
Rv2590|M.tuberculosis_H37Rv P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
MLBr_00484|M.leprae_Br4923 APAKLVVFDYHPEVDEQHDAVATARARLADSS--VVVESLTEVLGRG---
MAV_3471|M.avium_104 APTRLVVFDYHPQVDDQREAVQDAAARLSGTG--VAVQTLAELLERG---
MSMEG_2956|M.smegmatis_MC2_155 P-SRLVVFDYSHEVDDQREAFEAAKGKLAGTG--VVVETITDALDRG---
Mvan_2578|M.vanbaalenii_PYR-1 V-TRLVVFDHRAGVDDHRDALISASDRLRAANSPIEVETITDIVARG---
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 I-KQVVVFDYTPEVDDQREAFEAASTQLAGTG--IAIETLDAVIARG---
Mflv_2962|M.gilvum_PYR-GCK ALRRIYVIDGSVPALDELAEAGASVD------------------------
MUL_1722|M.ulcerans_Agy99 RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
MMAR_2117|M.marinum_M RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
Mb2621|M.bovis_AF2122/97 -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
Rv2590|M.tuberculosis_H37Rv -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
MLBr_00484|M.leprae_Br4923 KTLPATPIPVADDSADPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRSDG
MAV_3471|M.avium_104 KDLPAVAEPPADE--DSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRGSK
MSMEG_2956|M.smegmatis_MC2_155 -RSLADAPLYVPDEADPLTLLIYTSGSTGTPKGAMYPESKTATMWQAGSK
Mvan_2578|M.vanbaalenii_PYR-1 -SKLPVRAQFS-ADGDALSLLIYTSGSTGAPKGAMYPQHLVANSWRRLAR
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 AALPAAPLYAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDV
Mflv_2962|M.gilvum_PYR-GCK --AAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYEIRGAKA
MUL_1722|M.ulcerans_Agy99 WFEGG---YEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVVKSDLSTL
MMAR_2117|M.marinum_M WFEGG---YEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVAKSDLSTL
Mb2621|M.bovis_AF2122/97 WFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYYVAKSDLSTL
Rv2590|M.tuberculosis_H37Rv WFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTL
MLBr_00484|M.leprae_Br4923 NWFGP---TAASITLNFMPMSHVMGRGILYGTLGNGGTAYFAARSDLSTL
MAV_3471|M.avium_104 NWFGE---SAASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLSTL
MSMEG_2956|M.smegmatis_MC2_155 ARWDETLGVMPSITLNFMPMSHVMGRGILCSTLASGGTAYFAARSDLSTF
Mvan_2578|M.vanbaalenii_PYR-1 SFWGD-LGVFPAITLNFMPMSHVMGRGLLYGTLDAGGTAYFAARSDLSTF
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MAGTEN---LPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYFAASSDMSTL
Mflv_2962|M.gilvum_PYR-GCK CFPEH--LAKGEKLLVFLPLAHVLARALTIGAFSNG--VTLGFTSDIKNL
MUL_1722|M.ulcerans_Agy99 FEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQV
MMAR_2117|M.marinum_M FEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQV
Mb2621|M.bovis_AF2122/97 FEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQV
Rv2590|M.tuberculosis_H37Rv FEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQV
MLBr_00484|M.leprae_Br4923 LEDLKLVRPTELNFVPRIWETLYDESKRAVDRRLANSGSA-DRAAIKAEV
MAV_3471|M.avium_104 LEDLELVRPTELNFVPRIWETLYGEFQRQVERRLSEAGDAGERRAVEAEV
MSMEG_2956|M.smegmatis_MC2_155 LEDLALVRPTQLNFVPRIWDMLFQEYQSRLDNRRAE----GSEDRAEAAV
Mvan_2578|M.vanbaalenii_PYR-1 LEDLALVRPTQLSFVPRIWDTIHAEVSQELERRPSD----ATE------V
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 FEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASS-DTASAEAVAAEV
Mflv_2962|M.gilvum_PYR-GCK VPMFAVFQPTLVVSVPRVFEKVYN--------------------------
MUL_1722|M.ulcerans_Agy99 KAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAG
MMAR_2117|M.marinum_M KAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAG
Mb2621|M.bovis_AF2122/97 KAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAG
Rv2590|M.tuberculosis_H37Rv KAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAG
MLBr_00484|M.leprae_Br4923 MDEQRQSLLGGRYIAAMTGSAPTSPELKHGVESLL-EMHLLEGYGSTEAG
MAV_3471|M.avium_104 LAEQRQYLLGGRFTFAMTGSAPISPELRNWVESLL-EMHLMDGYGSTEAG
MSMEG_2956|M.smegmatis_MC2_155 LEEVRTQLLGGRFVSALTGSAPISAEMKSWVEDLL-DMHLLEGYGSTEAG
Mvan_2578|M.vanbaalenii_PYR-1 IADLRRSLLGGRYVTAMTGSAPLSPEMRAFVENLL-DVHLIDGYGSTEAG
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 KADIRDNLFGGRVSAVMVGSAPLSEELGEFIESCF-ELNLTDGYGSTEAG
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1722|M.ulcerans_Agy99 MILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYY
MMAR_2117|M.marinum_M MILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYY
Mb2621|M.bovis_AF2122/97 MVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYY
Rv2590|M.tuberculosis_H37Rv MVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYY
MLBr_00484|M.leprae_Br4923 MVLFDGEVQRPPVIDYKLVDVPDLGYFSTDQPYPRGELLLKTQNMFPGYY
MAV_3471|M.avium_104 MVLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFPGYY
MSMEG_2956|M.smegmatis_MC2_155 AVFIDGQIQRPPVIDYKLVDVPDLGYFATDRPYPRGELLVKSEQMFPGYY
Mvan_2578|M.vanbaalenii_PYR-1 AVFVDGRVQRPPVIDYKLVDVADLGYFSTDRPHPRGELLVKSETLFPGYY
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYY
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1722|M.ulcerans_Agy99 QRAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTV
MMAR_2117|M.marinum_M QRAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTV
Mb2621|M.bovis_AF2122/97 QRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAV
Rv2590|M.tuberculosis_H37Rv QRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAV
MLBr_00484|M.leprae_Br4923 KRPEVTATVFDSDGYYQTGDIVAEVGPDRLVYVDRRNNVLKLAQGQFVTV
MAV_3471|M.avium_104 KRAETTAGVFDEDGYYRTGDVFAEIAPDRLVYVDRRNNVLKLAQGEFVTL
MSMEG_2956|M.smegmatis_MC2_155 KRPEITAEMFDEDGYYRTGDIVAELGPDHLEYLDRRNNVLKLSQGEFVTV
Mvan_2578|M.vanbaalenii_PYR-1 KRPDVTAEMFDEDGYYRTGDIVAETGADQLTYLDRRNNVLKLSQGEFVTV
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 KRPEVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAV
Mflv_2962|M.gilvum_PYR-GCK -----------------TAELNAETGGKGKIFTAAANTAIEYS-------
MUL_1722|M.ulcerans_Agy99 SKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAVP--VEELKA
MMAR_2117|M.marinum_M SKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAVP--VEELKA
Mb2621|M.bovis_AF2122/97 SKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IENLKP
Rv2590|M.tuberculosis_H37Rv SKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IENLKP
MLBr_00484|M.leprae_Br4923 AKLEAAFSNSPLVRQIYIYGNSAHPYLLAVVVPTEDALATND--IEVLKP
MAV_3471|M.avium_104 AKLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALASGD--PETLKP
MSMEG_2956|M.smegmatis_MC2_155 SKLEAVFGDSPLVRQIYVYGNSARSYLLAVVVPTEEALSRWD--GDELKS
Mvan_2578|M.vanbaalenii_PYR-1 SRLEAVFGNSPLVRQIYVYGNSARPYLLAVVVPTEAALA-----GADAKA
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 ATLEAEYANSPVVHQIYVYGSSERSYLLAVVVPTPEAVAAAKGDAAALKT
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1722|M.ulcerans_Agy99 RLGDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLQNGLLTGIRKLARPQL
MMAR_2117|M.marinum_M RLGDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLENGLLTGIRKLARPQL
Mb2621|M.bovis_AF2122/97 VISESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQL
Rv2590|M.tuberculosis_H37Rv VISESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQL
MLBr_00484|M.leprae_Br4923 LIIDSLQKVAKEAD-LQSYEVPRDLIVETTPFSLENGLLTGIRKLAWPKL
MAV_3471|M.avium_104 KIADSLQQVAKEAG-LQSYEVPRDFIIETTPFSLENGLLTGIRKLAWPKL
MSMEG_2956|M.smegmatis_MC2_155 RISDSLQDAARAAG-LQSYEIPRDFLVETTPFTLENGLLTGIRKLARPKL
Mvan_2578|M.vanbaalenii_PYR-1 AVAESLQDVAKATG-LQSYEIPRDFLLETTPFTLENGLLTGIRKLARPRL
TH_1879|M.thermoresistible__bu -VGLSXQARARLADRLPAYMVPAAVVVLDRIPLTVNGKLD-RRALPAPEY
MAB_2962|M.abscessus_ATCC_1997 TIADSLQDIAKEIQ-LQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARPNL
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1722|M.ulcerans_Agy99 KKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGS
MMAR_2117|M.marinum_M KKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGS
Mb2621|M.bovis_AF2122/97 KKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGST
Rv2590|M.tuberculosis_H37Rv KKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGST
MLBr_00484|M.leprae_Br4923 KQHYGARLEQLYADLVEGQANALHVLKQSVANAPVLQTVSRAVGTILGVA
MAV_3471|M.avium_104 KQHYGERLEQMYADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLGSA
MSMEG_2956|M.smegmatis_MC2_155 KAHYGERLEQLYTDLAEGQANELRELRRNGADRPVVETVSRAAVALLGAS
Mvan_2578|M.vanbaalenii_PYR-1 RERYGEQLEALYTMLSEEQADELRELRRSGGERPALETVGRAAGALLGTT
TH_1879|M.thermoresistible__bu QRAD----------------------RYRAPETAVEKTLTEIFAHVLG--
MAB_2962|M.abscessus_ATCC_1997 KAHYGPRLEQMYAEIAEQQAAELRALHGVDPDKPALETVLKAAQALLGVS
Mflv_2962|M.gilvum_PYR-GCK -----------------------KALDSGGPGLVLKLKHALFDKLVYGKL
. : *
MUL_1722|M.ulcerans_Agy99 ASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDIDVPVGVIVSPANDLQAL
MMAR_2117|M.marinum_M ASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDIEVPVGVIVSPANDLQAL
Mb2621|M.bovis_AF2122/97 AADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRAL
Rv2590|M.tuberculosis_H37Rv AADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRAL
MLBr_00484|M.leprae_Br4923 TTDLPSNAHFTDLGGDSLSALTFGSLLRELFDIDVPVGVIVSPVNNLVAI
MAV_3471|M.avium_104 ASDLSPDAHFTDLGGDSLSALTFGNLLREIFDVDVPVGVIVSPANDLAAI
MSMEG_2956|M.smegmatis_MC2_155 VTDLRSDAHFTDLGGDSLSALSFSNLLHEIFDVDVPVGVIVSPATDLAGV
Mvan_2578|M.vanbaalenii_PYR-1 AGELEPSAHFTDLGGDSLSALTFANLLRDIFDVDVPVGVIVSPATDLQAL
TH_1879|M.thermoresistible__bu LERVGVDDSFFDLGGDSISAMRAVAAINTALDTDVAVRTLFEAP-TVRRL
MAB_2962|M.abscessus_ATCC_1997 SAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAANDLSGV
Mflv_2962|M.gilvum_PYR-GCK RAALGGRCHAAISGGAPLGAR--------LGHFYRGVGLSIYEGYGLTET
: ** .:.* * . :
MUL_1722|M.ulcerans_Agy99 ADYVE-----AARKPGSSRPTFASVHGASNEQVTEVHAGDLSLDKFIDAA
MMAR_2117|M.marinum_M ADYVE-----AARKPGSSRPTFASVHGASNGQVTEVHAGDLSLDKFIDAA
Mb2621|M.bovis_AF2122/97 ADHIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAA
Rv2590|M.tuberculosis_H37Rv ADHIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAA
MLBr_00484|M.leprae_Br4923 ADYIE-----RER-QGTKRPTFIAIHGRD---AGKVHASDLTLDKFIDVS
MAV_3471|M.avium_104 ASYIE-----AER-QGSKRPTFASVHGRD---ATVVRAADLTLDKFLDAD
MSMEG_2956|M.smegmatis_MC2_155 AAYIE-----GELR-GSKRPTYASVHG---RDATEVRARDLALGKFIDAK
Mvan_2578|M.vanbaalenii_PYR-1 ADYVE-----SARRHGSVRPTFESVHGHSGRPGTEVHARDLTLDEFVDAA
TH_1879|M.thermoresistible__bu SRQLEGGADTAPQGADLGAVTYESVHGAT---ATEVRAADLTLDRFIDAA
MAB_2962|M.abscessus_ATCC_1997 AKFVD-----EQRYSGGTRPTAETVHGAG---HTEIRAADLTLDKFIDEA
Mflv_2962|M.gilvum_PYR-GCK SAAIT-----------------------------VNRVGDLRVG-----S
: : :. ** :.
MUL_1722|M.ulcerans_Agy99 TLAEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLV
MMAR_2117|M.marinum_M TLAEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLV
Mb2621|M.bovis_AF2122/97 TLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLV
Rv2590|M.tuberculosis_H37Rv TLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLV
MLBr_00484|M.leprae_Br4923 TLTAAPVLAQPGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALV
MAV_3471|M.avium_104 TLASAPNLPKPATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALV
MSMEG_2956|M.smegmatis_MC2_155 TLSAAPGLPRSGTEIRTVLLTGATGFLGRYLALEWLERMDLVDGKVICLV
Mvan_2578|M.vanbaalenii_PYR-1 TLAHAPTLPGPRAEVRTVLLTGATGFLGRYLALEWLERMALVGGKLICLV
TH_1879|M.thermoresistible__bu TLRTAADLPRPTGQVQTVLLTGATGFLGRYLLLEWLRRLRRVDDTVICLV
MAB_2962|M.abscessus_ATCC_1997 TLHAAPSLPKAVGIPHTVLLTGSNGYLGHYLALEWLERLDKTEGKLIAIV
Mflv_2962|M.gilvum_PYR-GCK VGKLVPGNSMRLGEDGELLVRGGVVFNG-YWGNEEETRAVFTDGWFHTGD
. .. . :*: *. : * * : * . . .
MUL_1722|M.ulcerans_Agy99 RAKSDTEARARLEKTFDSGAPELLAHYRALAGDHLEVLAGDKGEADLGLD
MMAR_2117|M.marinum_M RAKSDTEARARLDKTFDSGDPELLAHYRALAGDHLEVLAGDKGEADLGLD
Mb2621|M.bovis_AF2122/97 RARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLD
Rv2590|M.tuberculosis_H37Rv RARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLD
MLBr_00484|M.leprae_Br4923 RAKSNEDARARLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELD
MAV_3471|M.avium_104 RARSDEEARARLDKTFDSGDPKLLAHYQQLAADHLEVIAGDKGEANLGLR
MSMEG_2956|M.smegmatis_MC2_155 RARSDDEARARLDATFDTGDATLLEHYRALAADHLEVIAGDKGEADLGLD
Mvan_2578|M.vanbaalenii_PYR-1 RAKDDAAARVRLDSTFDSGDPELLRHYRRLAADHLEVIAGDKADADLGLD
TH_1879|M.thermoresistible__bu RGRSDADARQRLEAVFDT-DPALRRHFRELAAERLQVIAGDKGQPNLGLD
MAB_2962|M.abscessus_ATCC_1997 RGKNAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLD
Mflv_2962|M.gilvum_PYR-GCK LGAIDDDG------------------FLTIVGRKKEIIVTAGGKN-----
. . : : : :::. ..
MUL_1722|M.ulcerans_Agy99 RQTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKI
MMAR_2117|M.marinum_M RQTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKI
Mb2621|M.bovis_AF2122/97 RVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKR
Rv2590|M.tuberculosis_H37Rv RVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKR
MLBr_00484|M.leprae_Br4923 RQTWRRLADTVDLIVDPAALVNHVLPYSELFGPNTLGTAELIRIALTSKQ
MAV_3471|M.avium_104 QDVWQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQ
MSMEG_2956|M.smegmatis_MC2_155 HDTWQRLADTVDLIVDPAALVNHVLPYSQMFGPNALGTAELIRIALTTTI
Mvan_2578|M.vanbaalenii_PYR-1 ARTWQRLADTVDLIVDPAALVNHVLPYRQLFAPNVLGTAELLRIALTTRM
TH_1879|M.thermoresistible__bu VQTWRRLAERVDLIVDSAAFVNSVLPYRELFGPNVVGTAELIRFALTAKL
MAB_2962|M.abscessus_ATCC_1997 ADTWQRLADTVDVIVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKI
Mflv_2962|M.gilvum_PYR-GCK --------------VAPAQLEDRLRAHPLISQAMAVGDQQPFIAALIT--
* .* : : : .: : . . * : : *:
MUL_1722|M.ulcerans_Agy99 KPYSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAG
MMAR_2117|M.marinum_M KPYSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAG
Mb2621|M.bovis_AF2122/97 KPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAG
Rv2590|M.tuberculosis_H37Rv KPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAG
MLBr_00484|M.leprae_Br4923 KPYIYVSTIGVGNQIEPAKFTEDSDIRVISPTRNINNNYANGYGNSKWAG
MAV_3471|M.avium_104 KPYTYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAG
MSMEG_2956|M.smegmatis_MC2_155 KPYVYVSTIGVGQGISPEAFVEDADIREISATRRVDDSYANGYGNSKWAG
Mvan_2578|M.vanbaalenii_PYR-1 KPFVYVSTIGVGAGIEPARFTEDADIRQISATRRIDDSYANGYGNSKWAG
TH_1879|M.thermoresistible__bu KPYNFVSTSDIGRQIEPDLFTEDADIRTISPTRTVDASYANGYGNSKWAG
MAB_2962|M.abscessus_ATCC_1997 KPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANGYGNSKWAG
Mflv_2962|M.gilvum_PYR-GCK --------------VDTEAFPGWKERHHKASDASVADLADD---------
: . * : : :. : :
MUL_1722|M.ulcerans_Agy99 EVLLREAHVLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATG
MMAR_2117|M.marinum_M EVLLREAHDLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATG
Mb2621|M.bovis_AF2122/97 EVLLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATG
Rv2590|M.tuberculosis_H37Rv EVLLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATG
MLBr_00484|M.leprae_Br4923 EVLLREAHDLCGLPVTVFRCDMILADTSYAGQLNVPDMFTRMMLSLAATG
MAV_3471|M.avium_104 EVLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRLMLSLVATG
MSMEG_2956|M.smegmatis_MC2_155 EVLLREAHDWCGLPVSVFRCDMILADTTYSGQLNLPDMFTRLMLSLVATG
Mvan_2578|M.vanbaalenii_PYR-1 EVLLREAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTRLIFSLVATG
TH_1879|M.thermoresistible__bu EVLLREAHDLCGLPVAVFRSGMILVDPTYAGQLNVTDTVSRMVLSIVATG
MAB_2962|M.abscessus_ATCC_1997 EVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATG
Mflv_2962|M.gilvum_PYR-GCK -----------------------------------PDLLAEIELAVKDAN
.* .:.: ::: :.
MUL_1722|M.ulcerans_Agy99 IAPGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----
MMAR_2117|M.marinum_M IAPGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----
Mb2621|M.bovis_AF2122/97 IAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----
Rv2590|M.tuberculosis_H37Rv IAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----
MLBr_00484|M.leprae_Br4923 IAPGSFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQSLHDRDG-----
MAV_3471|M.avium_104 IAPGSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITDSDTG-----
MSMEG_2956|M.smegmatis_MC2_155 IAPGSFYELDADGNRQRAHYDGLPVEFIAEAISTIGSQ---VTDG-----
Mvan_2578|M.vanbaalenii_PYR-1 VAPESFYHLATDGTRQRAHYDGLPVEFIAEAISTLGSD---VASG-----
TH_1879|M.thermoresistible__bu VAPKSFYRLGDDGSRQRAHFDGLPVDFVAEAVATLGWQIARTATGSPAGD
MAB_2962|M.abscessus_ATCC_1997 IAPGSFYQAHATGERPLAHYDGLPGDFTAEAITTLGTQ---VVDS-----
Mflv_2962|M.gilvum_PYR-GCK QAVS----------------------------------------------
*
MUL_1722|M.ulcerans_Agy99 FHTYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETA
MMAR_2117|M.marinum_M FHTYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETA
Mb2621|M.bovis_AF2122/97 FVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETS
Rv2590|M.tuberculosis_H37Rv FVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETS
MLBr_00484|M.leprae_Br4923 FTTYHVMNPHDDGIGMDEFVDWLID----AGCPIQRINDYDEWLRRFEIS
MAV_3471|M.avium_104 FQTYHVMNPYDDGIGLDEYVDWLVD----AGYSIERIADYSEWLRRFETS
MSMEG_2956|M.smegmatis_MC2_155 FETFHVMNPYDDGIGLDEYVDWLIE----AGYPVHRVDDYATWLSRFETA
Mvan_2578|M.vanbaalenii_PYR-1 FRTYHVMNPHDDGIGLDEYVDWLID----AGHPIRRVGDYPTWLQRFTVA
TH_1879|M.thermoresistible__bu FRTYHVMNPHDDGIGIDEYVDWLIE----AGHPIERIDDFGEWLRRFEAG
MAB_2962|M.abscessus_ATCC_1997 YETYDCVNPHADGVSLDNFVDWLIE----AGYPIARIDNYTEWFTRFDTA
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1722|M.ulcerans_Agy99 LRALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEA
MMAR_2117|M.marinum_M LRALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEA
Mb2621|M.bovis_AF2122/97 LRALPDRQRHTSLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEA
Rv2590|M.tuberculosis_H37Rv LRALPDRQRHASLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEA
MLBr_00484|M.leprae_Br4923 LRALPERQRHSSLLPLLHNYQK------PEKPLHGSLAPTIRFRTAVQNA
MAV_3471|M.avium_104 LRALPDRQRQYSLLPLLHNYRT------PEKPINGSIAPTDVFRAAVQEA
MSMEG_2956|M.smegmatis_MC2_155 LRALPERQRQASLLPLLHNYQQ------PSPPVCGAMAPTDRFRAAVQDA
Mvan_2578|M.vanbaalenii_PYR-1 ITALPERQRQASLLPLLHNYQH------PETPIRGSIAPTDRFREAVQDA
TH_1879|M.thermoresistible__bu LHALPERQRQHSVLQMLTLLRQQGGEPQPPEPRHGSDAPADRFEAAVKRA
MAB_2962|M.abscessus_ATCC_1997 IRSLPEKQKQHSLLPLLHAFEQ------PSAAENHGVVPAKRFQHAVQAA
Mflv_2962|M.gilvum_PYR-GCK ---KAEAIRKFRILPVDFTEDT------------GELTPTLKVKRKVVAE
.: :: :* : .*: .. *
MUL_1722|M.ulcerans_Agy99 KIGPD-----KDIPHVGAPIIVKYVSDLRLLGLL
MMAR_2117|M.marinum_M KIGPD-----KDIPHVGAPIIVKYVSDLRLLGLL
Mb2621|M.bovis_AF2122/97 KIGPD-----KDIPHLTAAIIAKYISNLRLLGLL
Rv2590|M.tuberculosis_H37Rv KIGPD-----KDIPHLTAAIIAKYISNLRLLGLL
MLBr_00484|M.leprae_Br4923 NIGQD-----KDIPHISPAIIAKYVSDLQLLGLV
MAV_3471|M.avium_104 KIGPD-----KDIPHVSPPVIVKYITDLQLLGLL
MSMEG_2956|M.smegmatis_MC2_155 KIGPD-----KDIPHVTADVIVKYISNLQMLGLL
Mvan_2578|M.vanbaalenii_PYR-1 KIGPD-----KDIPHVTPQIVIKYVTDLQRLGLL
TH_1879|M.thermoresistible__bu GINGG-----QGIPHVTPEVIVRYVTDLRQLGLL
MAB_2962|M.abscessus_ATCC_1997 GIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
Mflv_2962|M.gilvum_PYR-GCK KFAAD--------------IEALYAKG-------
: : * ..