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VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVLENSGADYPDL VPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLA RYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKG VLHESATICGNAFDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLV NSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLR PFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTD DDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDER VTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE IFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGE AIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVV IVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKI DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWR LSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVA LRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEE AARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQ YVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSF AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTR TARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGT ERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAG PGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGEL YIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGE VATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPL TVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN TTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKE LAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKL KPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRC GMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVA GSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLL ASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0101 | nrp | - | 100% (2512) | PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) |
M. tuberculosis H37Rv | Rv2590 | fadD9 | e-180 | 39.24% (1180) | fatty-acid-CoA ligase |
M. tuberculosis H37Rv | Rv2380c | mbtE | e-140 | 33.18% (1076) | peptide synthetase MBTE (peptide synthase) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 0.0 | 100.00% (2512) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_2696 | - | 1e-141 | 33.27% (1103) | amino acid adenylation domain-containing protein |
M. leprae Br4923 | MLBr_01996 | nrp | 0.0 | 69.05% (1008) | putative peptide synthase |
M. abscessus ATCC 19977 | MAB_4691c | - | 0.0 | 50.09% (1627) | non-ribosomal peptide synthetase PstA |
M. marinum M | MMAR_3097 | - | 0.0 | 49.56% (1705) | non-ribosomal peptide synthetase |
M. avium 104 | MAV_3239 | - | 0.0 | 55.49% (2078) | syringomycin synthetase |
M. smegmatis MC2 155 | MSMEG_0402 | - | 0.0 | 53.34% (1511) | linear gramicidin synthetase subunit D |
M. thermoresistible (build 8) | TH_3730 | - | 0.0 | 49.02% (1020) | PUTATIVE linear gramicidin synthetase subunit D |
M. ulcerans Agy99 | MUL_4858 | - | 0.0 | 66.18% (1020) | non-ribosomal peptide synthetase |
M. vanbaalenii PYR-1 | Mvan_2578 | - | 1e-178 | 38.64% (1180) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 MDSNAGALSLTRGQLDIWLAEETGRSGAKWHLGMLGRIEGIIEHGLLEQA MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VRQVIHEAEPLRAVFSELNGQVFQTVVDYPDTELAHHDLTGSPDPVGDAY MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RIAGSIQKAPMPLDGPLFRFALMQVRPDDFYFFVCCHHIVTDGIGMGLLC MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 HRIAAVYSAIATDAPVPAPIFGSLRSLVESESDYEGSEDYLDDAAYWASC MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GPLDDELRYGTPPAAAARLAEYEPSAPIQLDPAVVAKARELSHALGVRRA MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AVITAACALLVHGEVGGAEVVLDFPVSRRVRPEALLVPGMSSGVVPLRLT MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TSPYTSVADFCEHVATRIQEALRHQRFPLRDIESKTGFQRGGWPSRHAAV MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 NFIPTTRLADFAGAAGSGTVTHTGLVDQFGLVFIKNDDELFLSTTGVGEL MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 FPDCDARTLADRFERVLSEMTADPRRPLSAIDVRAEAQCPQLDLWSNRGA MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LTHPVPRPLSIPELFAEQVVRDPGAVAVSCGGRSVSYRGLDEASNRLAHL MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LISHGVGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPSVPDARLRF MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VLCDAGPVVVVTTAELADRLAGHGLTVVDIDGRAVYGQPSAALSIMPHPD MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DVAYLIYTSGTTGTPKGVAIPHHNVTRLLEAIDADLELVPGQGWAQCHSL MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AFDFSVWEIFGALLHGGRLVVVPEGVTRAPEELHALLVHERVSVLSQTPS MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AFYALHAVDTASPEQRQLALSVVVFGGEALEPARLSDWFQDHPQSPRLIN MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 MYGITETTVHASFREITVSDVVGTSSPIGAPLADLSFFVLDDWLRPLQAG MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AVGELYVAGAGVGYGYAGRTSLTATRFVACPFGGRGTRMYRTGDLVCWGS MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DGQLRYLGRADEQVKIRGYRIELGEVQSALAALEGVDQVAVIAREDRPGD MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 KRLVGYFTGSADPGELRETLTDRLPSYMVPAAIVVLESLPLTVNGKLDRN MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ALPAPEYRAVERYRRPATVVEETLAAIYAQVLGLERVGADDSFFELGGDS MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ILAMQVSSAVRMAGLACRPRDIFVQQTVARLAEVVVAGDTIAEPLDEGTG MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 PVTATPIMRWLKEIGGPVAEFNQTVVLQAPDGVTGAAVIAMLQAVLDRHA MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 MLRLRAEDHGNGGWLLSAAAPGAVEAAQCLESIDRLTDEALLAARSRLDP MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AAGAVLSGLWVDSTHRLVLIVHHLAVDGVSWRILLEDLNIAWTQQQDGRP MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 IALPRPGTSFRQWAELLSEYTRSEPVVEQAQRWQTVSAVPALLPPVDPEA MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DTYETAGQLSAALDTETTRLLLGAVPAAFHAGPQEILLIALGLALAEFSG MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TTQIAIDVEGHGRHEELGELSGAGARSIDLSRTVGWFTTKYPVSLDLDGL MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AWSSVVAGDAALGAMIKAAKEQARALPDGLTYGLLRYLNPAVDLAASDPS MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 IAFNYLGRVSGLTGAGWQLCPDSASLSRAASRVPTPLGHPLELNAIVIET MAV_3239|M.avium_104 ---MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNG--------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 EAGVLLNADWTWARSALDQTQVGRLNELWFQALTGICAHVRSGGGGLTPS MAV_3239|M.avium_104 --------------------------------VLGAGVSVRTLFEAPTVA MMAR_3097|M.marinum_M ------------------------------------MSGLSAAELAELSD Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DIAPAVLNQGQIDELSRQHHFTDLLPLTPLQQGLLYHSGTAR-GCDDVYA MAV_3239|M.avium_104 QLAPRVRGGGRTLARVVAGERPAVVPLS-FAQSRLWFLDQLQ-GPSPMYN MMAR_3097|M.marinum_M ILARTGDQRDGGQTAGGLVGVEDVMALTPLQQGLFALAMFTKSAADDPYT Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 MQLSLVLDGQLDPQQLRDAVQSVVDRHPHLAARFYERFDPPIQAIPTDPV MAV_3239|M.avium_104 MAAALKLQGPLDVSVLRAALADVIARHESLRTVFAVSDGTPHQVVIPAEQ MMAR_3097|M.marinum_M IAAPFDVFGQLDTVLLRNCAIATMHRHPNLRARFVQGKLPHPVQVVPSDV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VPWQYLALDFNGTDIDGQVQEISAAERVAVGDLANRCAIRAALIRTADEQ MAV_3239|M.avium_104 ADIGWDVVDTAGWSPARMKEAIDAAAG-HAFDLSTEIPLRATLFRNSLDE MMAR_3097|M.marinum_M DLSWRQVVAMP-----EEVASLEADEQRSGFDLERGLTMRFLLVELPNER Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 HRFILTTHHIVLDGWSMPILIQEIFASLRGQRLRPAASYRSFVTWLSERD MAV_3239|M.avium_104 HVLVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPDWVPLPVQYIDYA MMAR_3097|M.marinum_M WRFIITAHHIVIDGWSLAVFVNELFALYRAGGAIDALAAPPRPFRDYLGW Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 QVAAQHA----------------WRKAMAGFDAPTLVG--PSTPDGPGHR MAV_3239|M.avium_104 LWQRAQFGDLEDPDSPIAGQLRYWQEALAGLPERLALP--TDRPYPAVAD MMAR_3097|M.marinum_M LGGWDSQSGEQ-----------FWRDYLAGLSAPTMLSRALAGGQGGQLA Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 G---VESFQLPEEITKNVGELARSRQTTVNVVLQGAWALLLSSLCGHGDV MAV_3239|M.avium_104 HRGARVDIDWPASLQQQVSALARVHNATSFMVVQAGLAVLLAKLGASCDV MMAR_3097|M.marinum_M EEPQRIELCLGAEVTARLVDGARSRGVTVNSLVQVAWALVLGALTGRDDV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AFGTTVSGRPAEVLGAESMVGLLINTVPVRATIGAATTTAELLGQLQGRH MAV_3239|M.avium_104 AVGFPIAGRGDP--ALDDLVGFFVNTLVLRVDLSGDPTVGEILARVRQRS MMAR_3097|M.marinum_M VFGIAVSGRPSELAGVQSMVGLFINTVPLRVRLDPQAVIADLCAAVRRDT Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 NDTLEHQHLALSDIHR---ITGQERLFDTLMVFENYPIDVTERWDIEGLA MAV_3239|M.avium_104 LAAYEHQDVPFEILVERLNPTRSLAHHPLIQVMLTWRGDDPTRLRLGELE MMAR_3097|M.marinum_M ALVREYAYFSHAWLRQAAGVGEMFDTLLVFENFPTGGLAVGKDVPVGAAT Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VTGFDFRESNHYPLAVQVLPG--------SALGLRIEYDSGVFDCAAVKA MAV_3239|M.avium_104 VAALPIDIGTARMDLTFSLCERWTEEGRPAGIAGTVEFRTDVFDADTIRT MMAR_3097|M.marinum_M FRRVAAHSPTHFPVTVTAEFARDQLTLMIAATGDALSVLTPETGLG-VAD Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LFGRLTTILSAMTADPGLPLSSIDLLDDAVRTQLDTWSGRESLIDPPAV- MAV_3239|M.avium_104 LTERLRRVLDVLTADPGRHLSSIEVLEDTEFARLDIFGNRAALGRSTTG- MMAR_3097|M.marinum_M LVQRLGRVLVAMTGDVGVRVSSLDVLDSVERVRLDGWGNRAVLGASVPVG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 KSIPELFGEQVERSPGAIAVTCDGRSLTYRELDESANRLARVLADRGAGS MAV_3239|M.avium_104 ASVPALFGAWAQRVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDR MMAR_3097|M.marinum_M VSIPALFDAQVVRDRDAVALSFEGQSLTYGELDEASNRLARFLVGLGAGP Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GETVALLFSRSAEAIVAMLAVLKTGAAYVPVDPALPLARIEFMVADTAPI MAV_3239|M.avium_104 GQYVGLLLDRSAEAVVAILGVLKAGAAYVPMDPAVPAARIAFIVADADLR MMAR_3097|M.marinum_M GQRVALVFGRCAQAVTAILAVLKTGAAYVPIDPGLPAARVQFMVADAGPV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LAVTTTEHRPRLGDIELCIIDINEPSPDVQAETAPPGPTPDD--IAYIIF MAV_3239|M.avium_104 VVVTDAGSRSRLTGLGAAIVDLDDPALADYPATEPAGPGPAAGDIAHVIY MMAR_3097|M.marinum_M AVVTTGGWGAGLDGCGCVVVDVADAGVEACAGTG--LVAPAADDIAYLIY Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TSGTTGTPKGVAIAHRNVPGLFDALNAQVPSGTGQVWAQWHSYSFDVSVW MAV_3239|M.avium_104 TSGTTGEPKGVAVSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVW MMAR_3097|M.marinum_M TSGTTGIPKGVAVSHRNVVALVESLASSVPVAG--VWSQWHSYAFDVSVC Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 EIFGALLHGACLLVVTEQAAASPGELHELLVTQRVSVLSQTPSAAGMIS- MAV_3239|M.avium_104 EIWAALLHGGRLVVVSDAVARSPDDLRRLLIRERVTVLTQTPSAAGALS- MMAR_3097|M.marinum_M EIWGALLSGGRLVVVPEQVVGSPEDFLALLVAERVSVLSQTPSAFYALQG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 --------PQGLESTALVVAGEACPPELVDRWAPGR----VMVNAYGPTE MAV_3239|M.avium_104 --------PQGLDSVALVIGAEPCPPELVDRWAPDR----VMINVYGPTE MMAR_3097|M.marinum_M AVAVRSGLGRELRVEAVLLAGEAFEPQRAGVWLARRPGLARLINLYGTTE Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ATVYASISAPL--QSGSPVL-IGAPVPGVALFVLDQWMRPAPPGVAGELY MAV_3239|M.avium_104 TTMWVSHSRPL--AAGSGAPPIGSPVAGASFFVLDPWLCPAPVGVTGELY MMAR_3097|M.marinum_M TTVHASVREIVGADADSAVSPIGVPLGHLGFFVLDGWLRPVPVGVVGELY Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VAGRGVGLGYWRRTGLTSTRFVACPFGEPGGRMYRTGDLVQWDDGGQLRY MAV_3239|M.avium_104 VAGAGVGAGYVGRAALTASRFVACPFGGTGTRMYRTGDLVRWGADGQLHY MMAR_3097|M.marinum_M VAGVGVGVGYWGRGSLTGSRFVACPFGGVGERMYRTGDLVCWGRDGQLQY Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LGRADEQVKIRGYRIELGEVQAALATLDGVTQAVVIAHEDQGGTLRLVGY MAV_3239|M.avium_104 VGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAVIAREDSPGHKRLVAY MMAR_3097|M.marinum_M RGRVDDQVKVRGYRIELGEVQAALGAVDGVGQAVVVVREDRGGDRRLVGY Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VVGKADPDRIRTQLAARLPGYMVPAAVVVIDALPLTVSGKLDRRALPAPD MAV_3239|M.avium_104 LTGTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKLDTRALPAPE MMAR_3097|M.marinum_M VTGAVDPVVVRGVLGQRLPGYMVPAAVVVVAGLPLTVNGKLDRRALPAPE Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 YVDAARYRAPSNPTEEILTDIYARVLGHERVGIDDSFFDLGGDSLSAMRL MAV_3239|M.avium_104 LRAENRYRAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMRL MMAR_3097|M.marinum_M YGDGDRYRAPVGPVQEILAGIYAEVLGLERVGVEDSFFELGGDSLSAMRL Mflv_2696|M.gilvum_PYR-GCK ---------------------------------------MTDTDLDARRL Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LAGINAALNTGVTVRTLFDAPTVAQLCTRISRDET---RVAPLTARERPA MAV_3239|M.avium_104 ITAVNAELDADLTVRALFEAPTVAQLAPRVAAGTG---RAGRLVAAERPA MMAR_3097|M.marinum_M IAAVNAGLGVDLSVRVLFEWPTVAGLASCVGGVSGSVVPVVPLVAGPRPA Mflv_2696|M.gilvum_PYR-GCK ELLRRRLAGSGLREQD----------------------PAEPVAVAADPA Rv0101|M.tuberculosis_H37Rv ------------------------------------------------MH Mb0104|M.bovis_AF2122/97 ------------------------------------------------MH MLBr_01996|M.leprae_Br4923 ----------------------------------------MTAPNTRRVD MUL_4858|M.ulcerans_Agy99 ----------------------------------------MTAPEIGCAE Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RVPLSFAQSRLWFLDQLQGPSAIYNMTAAFRIDGELDADALAAAFTDVVA MAV_3239|M.avium_104 VLPLSFAQSRLWFIDQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVA MMAR_3097|M.marinum_M VVPLSFTQSGLWFLEQVQGPSAVYNMAAAFRLGGGLDVDALGAAWVDVVG Mflv_2696|M.gilvum_PYR-GCK RGEFTDGQKRMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVAR Rv0101|M.tuberculosis_H37Rv RVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLD Mb0104|M.bovis_AF2122/97 RVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLD MLBr_01996|M.leprae_Br4923 RVPLSRSQQNIYNGMLQDNDPALYFIGKSYRFHQLELSVFLAALEATILK MUL_4858|M.ulcerans_Agy99 AIPLSKSQQNLYNGVLQDNDPALYLIGKRYRFHPLALSNFLVALEASVLN Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RHESLRTLFEAPDGVPHQMVMPAGGAEPGWEVIDAGDWSVGQLREAIDEI MAV_3239|M.avium_104 RHESLRTLFPAPDGAPRQVVLEAERAEVDWQVVDAARWPASWLAEATHEA MMAR_3097|M.marinum_M RHESLRTVFPAVGGVPQQVVVPVERADFGWRVVDAGGWSVGRLGEAVDAV Mflv_2696|M.gilvum_PYR-GCK RHPVLRTTFAADEAGEPQRTVHDDLLPG-WTVQDISELSEHARRLRLEVL Rv0101|M.tuberculosis_H37Rv NPVQLCVLEN--SGADYPDLVPRLRFGDIVRVGS--------ADEHLQST Mb0104|M.bovis_AF2122/97 NPVQLCVLEN--SGADYPDLVPRLRFGDIVRVGS--------ADEHLQST MLBr_01996|M.leprae_Br4923 NPGQLCVLEAPSTEGDYPDLVPRLQFGDIVRVRSDEQPQTDSRDYDLMHA MUL_4858|M.ulcerans_Agy99 NPVQLCVLQMAATGADYPQLVPRLQFSDLVLVRSAAQGQPDGPGADLEHT Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 SR----HAFDLSAEIPLKAALFRVTDNEHALVVVVHHIAADGWSIAPLMA MAV_3239|M.avium_104 AR----YTFDLATEIPLRAWLFRRNHDEHVLVAVVHHIAADGWSLTPLVR MMAR_3097|M.marinum_M AG----YAFSLATEIPLRAVLFRVSADEHVLVCVVHHIAGDGWSMTPLAR Mflv_2696|M.gilvum_PYR-GCK AQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWRVFFA Rv0101|M.tuberculosis_H37Rv WCSG-----ILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEA Mb0104|M.bovis_AF2122/97 WCSG-----ILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEA MLBr_01996|M.leprae_Br4923 WSPD-----ILAKPLVRYTVRTDKNGFVARLDVFTHHILVDGGAIRIIEE MUL_4858|M.ulcerans_Agy99 WSSG-----ILDRPLLRYTVSTDEGGNVCGLDVHTHHILLDGGATGIIEA Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DLGTAYASRCAGEAPAWADLPVQYADYSLWQRAQFGELQDSDSPIARQLR MAV_3239|M.avium_104 DLGAAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPDSPIATQLQ MMAR_3097|M.marinum_M DLGVAYAARCAGCVPGWAPLAVQYGDYTLWQRARLGDLGDEGSPIAAQLA Mflv_2696|M.gilvum_PYR-GCK DLTRAYTGAELGPTPAPVVEPPTSDED---------------------LR Rv0101|M.tuberculosis_H37Rv DLARYLTTDPAG-----ETPSVGAGLAKLREAHRRETAKVEESRGRLSAV Mb0104|M.bovis_AF2122/97 DLARYLTTDPAG-----ETPSVGAGLAKLREAHRRETAKVEESRGRLSAV MLBr_01996|M.leprae_Br4923 NLAHHLDTDNR-----LEIPCIRQALDKLAEAHRREATKVEESLQRLANV MUL_4858|M.ulcerans_Agy99 DLAHFLAASLEPAG-VGEMPTLSQGLAKLAAAHLRETTKVAEALRRQADA Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 YWHGALAGLPERITLPTDRPYPLAADQRGATIAVNWPVELQRQIAELAAE MAV_3239|M.avium_104 YWQRALAGMPERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLART MMAR_3097|M.marinum_M YWQRVLAGMPERLALPTDRPYPPVADHRGGRVGIDWSVGLQQQIARVARE Mflv_2696|M.gilvum_PYR-GCK FWRSAMTDLPEPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAARE Rv0101|M.tuberculosis_H37Rv VQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEA Mb0104|M.bovis_AF2122/97 VQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEA MLBr_01996|M.leprae_Br4923 VQRELADEVRNGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALSET MUL_4858|M.ulcerans_Agy99 VQRELTAEAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALSEA Mvan_2578|M.vanbaalenii_PYR-1 ----------------------------------------------MSTD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 NNATSFMVVQAALLILLSRLSANSDVAVGFPIAGRRDPALDQLVGFFVNT MAV_3239|M.avium_104 HNATSFMVVQAALAVLLSTLSANPDVAVGFPIAGRRDPALDDVVGFFVNT MMAR_3097|M.marinum_M HNATSFMVVQAALAVVLAKISASSEVAVGVPVAGRGDRGLDELVGMFVNT Mflv_2696|M.gilvum_PYR-GCK AGATPYMVMLAAFGALLHRYTHADDVLIASPVLLRG-PDSEDVIGYHGNS Rv0101|M.tuberculosis_H37Rv QRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS Mb0104|M.bovis_AF2122/97 QRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS MLBr_01996|M.leprae_Br4923 KQVPLNILVATAAVAVDASLRQSTEGLLVHAVDNRFGDPYLDVATCLVNS MUL_4858|M.ulcerans_Agy99 QQVPLNVLVAAAAVAVQAGLWQSTESLLVHAVDNRFGDPELNVATCLVNS Mvan_2578|M.vanbaalenii_PYR-1 TREDRLARRIADLYATDPQFAAAAPDDAISHAIDQPGTHLPVIVQTVLDG MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LVLRADLAGNPTICEVLEQVRVRSLEAFDNQDVPFEVLVDRLNPVRSLAH MAV_3239|M.avium_104 LVLRVDLADDPSIAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAH MMAR_3097|M.marinum_M LVLRVDMSADPTVADLLAQVRASSLDAYEHQDVPFEVLVERLNPVRSLTH Mflv_2696|M.gilvum_PYR-GCK AVMRLRPQPMQTFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDRRHGA Rv0101|M.tuberculosis_H37Rv VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSH Mb0104|M.bovis_AF2122/97 VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSH MLBr_01996|M.leprae_Br4923 VAHSIRFPPFASVQDVVRTLDRSYVKAIRLRWLREEYYRRIYLALNQTSH MUL_4858|M.ulcerans_Agy99 VAHALRFRPFASVREVVRDLDRGYVKAVRRRWIREEHYRRMYLAINRTSH Mvan_2578|M.vanbaalenii_PYR-1 YAERPALGQR---------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 HPVVQVALAWQNFAGRHVNDSAAGVELGDLRISQMPVETRTARMDVNFSL MAV_3239|M.avium_104 HPLVQVMLAWQ-------NNDPVDVSLGDVHVTPMPLENQVARMDLVWSL MMAR_3097|M.marinum_M HPLVQVMLAWQNFPG-QLSDPGSGLVLGDVQVTAVPVDTGSARIDLAFFV Mflv_2696|M.gilvum_PYR-GCK ERMTRVSFGFREPDGGGFSPPGVTCRRAELRGQITQLPLG---------- Rv0101|M.tuberculosis_H37Rv VEALTLNFIREPCAPGLRPFLSEVPIATDIGPVEG--------------- Mb0104|M.bovis_AF2122/97 VEALTLNFIREPCAPGLRPFLSEVPIATDIGPVEG--------------- MLBr_01996|M.leprae_Br4923 IEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEG--------------- MUL_4858|M.ulcerans_Agy99 VQALTLNFIRESCAPGLRPFLSEAPVATEIGPIEG--------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ------------------------------------------MTAEPSTR TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AERWTKSGEPAGIGGTVEFRTDVFDARTIQSLVTRLQRVLTAITANPAAR MAV_3239|M.avium_104 AERWTADGRPDGIDGTVEFRTDVFDAASIETLVRRLQRVLLAMTADPARP MMAR_3097|M.marinum_M GERWSEAGEPAGIGGGVEFRTDVFDAGSIEMLIERLGRVLVAMTGDVGVR Mflv_2696|M.gilvum_PYR-GCK ---LMVELHESGAVVEAEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTV Rv0101|M.tuberculosis_H37Rv --------------MTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAER Mb0104|M.bovis_AF2122/97 --------------MTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAER MLBr_01996|M.leprae_Br4923 --------------MTVACVLNEDERTLDLSIWNRVDLPQGKSCTRVAKR MUL_4858|M.ulcerans_Agy99 --------------TTVACVLDEQRHTLNLAIWDRADLPERNTGAGVAAR Mvan_2578|M.vanbaalenii_PYR-1 ---------------AVRFVTDPATGRTTTELLPRFETITYAELSRRIHA MSMEG_0402|M.smegmatis_MC2_155 TLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAV TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 -LSVVDLLDDDERCRLSVLGNHATLARTPSRPASVTGLFAEKVSRTPEAV MAV_3239|M.avium_104 -VSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAV MMAR_3097|M.marinum_M -VSSLDVLDSVERVRLDGWGNRAVLGASVPVGVSIPALFDAQVVRDRDAV Mflv_2696|M.gilvum_PYR-GCK -LSRLELMDGDDAEWLRRVSHGPEFDVP---AATIGELIEARTDLTPDTV Rv0101|M.tuberculosis_H37Rv IAAALESMAAMWDRPIAMIVN-DWFGIGPDGTRCQGDWPAR--QPSTPAW Mb0104|M.bovis_AF2122/97 IAAALESMAAMWDRPIAMIVN-DWFGIGPDGTRCQGDWPAR--QPSTPAW MLBr_01996|M.leprae_Br4923 IAAALELMAAAWDQPIAMIVN-EWFGISSDGALCLGNEVTQTTRPLAPAW MUL_4858|M.ulcerans_Agy99 IGAALESMAALWDQPIAMTAN-EWFEVGADGLPCRTETAGRPRPPSAPAW Mvan_2578|M.vanbaalenii_PYR-1 VTAALTDVHP--GDRVAVLGFTSIDYTTVDMALAMLGAVAVPLQTSAPAT MSMEG_0402|M.smegmatis_MC2_155 ALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSI TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AVSCGERSWTYRELDSAANRLAHLLIDQGAGPGQVVALLSNRSAEAIAAI MAV_3239|M.avium_104 AISCGERSWTYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSI MMAR_3097|M.marinum_M ALSFEGQSLTYGELDEASNRLARFLVGLGAGPGQRVALVFGRCAQAVTAI Mflv_2696|M.gilvum_PYR-GCK AVVYEGRRYTYREINESANRVAHWLIGQGIGAEDRVAVLMDRSPELLITA Rv0101|M.tuberculosis_H37Rv FLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLL Mb0104|M.bovis_AF2122/97 FLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLL MLBr_01996|M.leprae_Br4923 FLDPGGSVHLTVDKRRYVHPWIAWLVRGSVVPGDVLVFTDDNTDKTIDLL MUL_4858|M.ulcerans_Agy99 FVDAAPGLRQFLDRRRQVYPWVGWLVCHGVAPGDVLVCADDNTDKTVDLL Mvan_2578|M.vanbaalenii_PYR-1 TVRPIVAETEPVVIASSVDALTDAVGLALDAPTVTRLVVFDHRAGVDDHR MSMEG_0402|M.smegmatis_MC2_155 LSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLA TH_3730|M.thermoresistible__bu ----------------------------------VTTAELGARLHRSGVP MAB_4691c|M.abscessus_ATCC_199 LGILKTGAAYLPIDPAVPDARLTFVLADAGPVVAVTTTDLADRLDGRGLA MAV_3239|M.avium_104 LAVLKTGAAYVPIDPGLPSARIDFMLADAVPVVTVTTAELRASAGDPDR- MMAR_3097|M.marinum_M LAVLKTGAAYVPIDPGLPAARVQFMVADAGPVAVVTTGGWGAGLDGCGCV Mflv_2696|M.gilvum_PYR-GCK LGIIKAGAVYLPVDPSYPQDRMSFVLSDSDPTLVIREPVAGLDGHRTDNP Rv0101|M.tuberculosis_H37Rv IACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGH Mb0104|M.bovis_AF2122/97 IACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGH MLBr_01996|M.leprae_Br4923 IACHLAGCGYSVCDTVAEVPLRAKAITDHGGGVSARVIDVAATQLAVTPD MUL_4858|M.ulcerans_Agy99 LACHLAGCGYSMCESVDDLSLRAKTIGEHCEGISAHPVDVAAVRLGAVPD Mvan_2578|M.vanbaalenii_PYR-1 DALISASDRLRAANSPIEVETITDIVARGSKLPVRAQFSADG-------- MSMEG_0402|M.smegmatis_MC2_155 VIDMA--DPAIDRRP-SDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHN TH_3730|M.thermoresistible__bu VIHID--DPAAPGQAGATTGPAPAPDDIAYIIYTSGTTGVPKGVAVTHRN MAB_4691c|M.abscessus_ATCC_199 IIDIRGVGPHPPDAGFDGAIPDPEPDHTAYLIYTSGTTGVPKGVALSHRN MAV_3239|M.avium_104 VVAIDDPAPHVPRIG---GRAAPAPDDIAYVIYTSGTTGVPKGVAVTHHN MMAR_3097|M.marinum_M VVDVADAGVEACAGT---GLVAPAADDIAYLIYTSGTTGIPKGVAVSHRN Mflv_2696|M.gilvum_PYR-GCK TDDVR--------------VRPLRPENAAYLIYTSGSTGQPKGVPVPHRP Rv0101|M.tuberculosis_H37Rv DELRKVVDERVTQVT----HDALLATKTAYIMPTSGTTGQPKLVRISHGS Mb0104|M.bovis_AF2122/97 DELRKVVDERVTQVT----HDALLATKTAYIMPTSGTTGQPKLVRISHGS MLBr_01996|M.leprae_Br4923 NEQSKLADKLIKQAA----QDISLADKTAYIMPTSGSTGQPKLVQVSHGS MUL_4858|M.ulcerans_Agy99 HALQERIGQRLDQVA----RDPLLATKAAYIMPTSGTTGQPKLVRISHGS Mvan_2578|M.vanbaalenii_PYR-1 -------------------------DALSLLIYTSGSTGAPKGAMYPQHL : : ***:** ** . .: MSMEG_0402|M.smegmatis_MC2_155 VTQLVSALHADLPSGP---GQVWSQWHSLVFDVSVWEIWGALLHGGRLVV TH_3730|M.thermoresistible__bu VAALLSALDAELASG-----QVWTQCHSLAFDFSVWEIWGPLLYGGRVVI MAB_4691c|M.abscessus_ATCC_199 VTQLLDSLDAGLPHP-----GVWSHSHSLAFDVSVWEIFGALLSGGRVVI MAV_3239|M.avium_104 VTQLLGSLDDRLGLG-----RVWSQCHSLAFDFSVWEIFGALLRGGRLVI MMAR_3097|M.marinum_M VVALVESLASSVPVAG-----VWSQWHSYAFDVSVCEIWGALLSGGRLVV Mflv_2696|M.gilvum_PYR-GCK VAEYFVWFKDEYEISE---SDRLLQVASPSFDVSIGEIFGTLACGGRLVI Rv0101|M.tuberculosis_H37Rv LAVFCDAISRAYGWGA---HDTVLQCAPLTSDISVEEIFGGAACGARLVR Mb0104|M.bovis_AF2122/97 LAVFCDAISRAYGWGA---HDTVLQCAPLTSDISVEEIFGGAACGARLVR MLBr_01996|M.leprae_Br4923 LALFCDAVRNAYGWGA---HDTILQCAPLTSDISVEEIFGGAICGSKLVR MUL_4858|M.ulcerans_Agy99 LAAFCAAIGPSYGWNS---QDTILQCAPLTSDISVEEIFGAAVCGAELVR Mvan_2578|M.vanbaalenii_PYR-1 VANSWRRLARSFWGDLGVFPAITLNFMPMSHVMGRGLLYGTLDAGGTAYF :. . : . .. ::* *. MSMEG_0402|M.smegmatis_MC2_155 VPESVGSSPDDLHNLLITEKVSVLC---------QTPS------AAGMLS TH_3730|M.thermoresistible__bu VPDPVVRSPEDLHALLAAEQVGMLS---------QTPSAFYALQTADSLQ MAB_4691c|M.abscessus_ATCC_199 ASEGATSSPEDLHALLIREHVTVIT---------QTPS------AARALP MAV_3239|M.avium_104 VPDDVVRSPEDLHALLIGEGVTVLS---------QTPS------AAAALS MMAR_3097|M.marinum_M VPEQVVGSPEDFLALLVAERVSVLS---------QTPSAFYALQGAVAVR Mflv_2696|M.gilvum_PYR-GCK PKPDGLTDVAYLTELLQREGITAMH---------FVPS----LLGLFLSL Rv0101|M.tuberculosis_H37Rv SAAMKTGDLAALVDDLVARETTIVD---------LPTAVWQLLCADGDAI Mb0104|M.bovis_AF2122/97 SAAMKTGDLAALVDDLVARETTIVD---------LPTAVWQLLCADGDAI MLBr_01996|M.leprae_Br4923 STAMKTGDLAELARDIFVQRATVID---------LPTAVWHLLCDHSDAI MUL_4858|M.ulcerans_Agy99 SAAMKTGDLGGLARDIHALGPTVVD---------LPTAVWHLLCEDGDAV Mvan_2578|M.vanbaalenii_PYR-1 AARSDLSTFLEDLALVRPTQLSFVPRIWDTIHAEVSQELERRPSDATEVI : : MSMEG_0402|M.smegmatis_MC2_155 PE---GLESTTLIVAGEACPTELVDRWAPGR-----VMINAYGPTEATIY TH_3730|M.thermoresistible__bu PEQARQLQLQTVVFGGEALEPQRLSAWMRNHPER-PRLINMYGITETTVH MAB_4691c|M.abscessus_ATCC_199 RE---GLDSAALVVVGEACPAEVVDQWAPGR-----VMINAYGPTETTMC MAV_3239|M.avium_104 PE---RLESVALVLGGEACPVELMDRWAPGR-----LMVNQYGPTETTLY MMAR_3097|M.marinum_M SGLGRELRVEAVLLAGEAFEPQRAGVWLARRPGL-ARLINLYGTTETTVH Mflv_2696|M.gilvum_PYR-GCK PGVNQWRTLERVPIGGEALPGELADRFHATFD---ALLHNFYGPTETIIN Rv0101|M.tuberculosis_H37Rv DAIG-RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVV Mb0104|M.bovis_AF2122/97 DAIG-RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVV MLBr_01996|M.leprae_Br4923 DEIN-RSCLRQIVIGGEAVRPCAVDKWIDSGASQGISLMSTYGPTETTVV MUL_4858|M.ulcerans_Agy99 DVIG-RSRLRQIVIGGESIRTSTVDKWVNSPALAPISLVSSYGPTEATVV Mvan_2578|M.vanbaalenii_PYR-1 ADLRRSLLGGRYVTAMTGSAPLSPEMRAFVENLLDVHLIDGYGSTEAGAV . : . ** **: MSMEG_0402|M.smegmatis_MC2_155 AAMSEP--LTAGTGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGH TH_3730|M.thermoresistible__bu ASFREIGAADLDDNTSPIGRPLPHLAFFVLDGWLRPVPPGVVGELYVAGA MAB_4691c|M.abscessus_ATCC_199 VAISAP--LTAGQG-VPIGTPVTGAALFVLDESLRQVPVGVVGELYVAGR MAV_3239|M.avium_104 ATMTTP--LRAGGAAVPIGSPVPGAALFVLDGRLRRVPPGVVGELYVAGR MMAR_3097|M.marinum_M ASVREIVGADADSAVSPIGVPLGHLGFFVLDGWLRPVPVGVVGELYVAGV Mflv_2696|M.gilvum_PYR-GCK TTRYKV-EGTQGSRIVPIGTPKINTTVHLLDDALRPVPVGAIGEIYIGGG Rv0101|M.tuberculosis_H37Rv ATFLPI--------VCDQTTMDG-ALLRLGRPILPNTVFLAFGEVVIVGD Mb0104|M.bovis_AF2122/97 ATFLPI--------VCDQTTMDG-ALLRLGRPILPNTVFLAFGEVVIVGD MLBr_01996|M.leprae_Br4923 VTYLPI--------VCAPMTVESDARLRLGWPIVPNTVFIAFGELVIVGD MUL_4858|M.ulcerans_Agy99 ATHLPI--------VYDGIAAAAHTRLRVGLPMVPNTVFIAFGEVVIAGP Mvan_2578|M.vanbaalenii_PYR-1 FVDGRVQ---------RPPVIDYKLVDVADLGYFSTDRPHPRGELLVKSE . **: : . MSMEG_0402|M.smegmatis_MC2_155 GVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRA TH_3730|M.thermoresistible__bu GLATGYVSRSDLTSTRFVACPFGPPGTRMYRTGDLVRWDTGGELHYIGRA MAB_4691c|M.abscessus_ATCC_199 GVGYGYVGRAPLTSTRFVACPFGDPGTRMYRTGDLVCWRPDGQLNYLGRA MAV_3239|M.avium_104 GVAAGYLGRAALTASRFVACPFGGTGTRMYRTGDLARWGADGQLHYVGRA MMAR_3097|M.marinum_M GVGVGYWGRGSLTGSRFVACPFGGVGERMYRTGDLVCWGRDGQLQYRGRV Mflv_2696|M.gilvum_PYR-GCK HVARGYHRRPALTAERFVADPFT-VGGRLYRSGDLARRNADGDLEFVGRA Rv0101|M.tuberculosis_H37Rv LVADGYLGIDGDGFG--TVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK Mb0104|M.bovis_AF2122/97 LVADGYLGIDGDGFG--TVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK MLBr_01996|M.leprae_Br4923 LVSVGYLGIDSRNFG--TVTTTDGSCRRAFATADCVILDDEGFPVFSGRK MUL_4858|M.ulcerans_Agy99 LVSDGYLGIDESSFG--AVAPGDGSQLRAFATADRVTIDEEGFPVFAGRK Mvan_2578|M.vanbaalenii_PYR-1 TLFPGYYKRPD-------VTAEMFDEDGYYRTGDIVAETGADQLTYLDRR : ** . . : :.* . . : .* MSMEG_0402|M.smegmatis_MC2_155 DEQVKIR-GYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITG TH_3730|M.thermoresistible__bu DEQVKIR-GYRIELGEIQAALARLDGVDQAAVIAREDRPGDKRLVGYITG MAB_4691c|M.abscessus_ATCC_199 DEQVKIR-GHRIELAEIQAVLASLGGVEEAVVIAREDRPGDKRLVGYITG MAV_3239|M.avium_104 DEQVKIR-GFRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYITG MMAR_3097|M.marinum_M DDQVKVR-GYRIELGEVQAALGAVDGVGQAVVVVREDRGGDRRLVGYVTG Mflv_2696|M.gilvum_PYR-GCK DDQVKIR-GFRIELGEVAAAISVDPSVGQAVVLGQDLPGLGMSLVGYVTP Rv0101|M.tuberculosis_H37Rv DAVVKIS-GKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTRE Mb0104|M.bovis_AF2122/97 DAVVKIS-GKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTRE MLBr_01996|M.leprae_Br4923 DAVVKIS-GKRVDTAELIRRISTDPNVSDVAVEVYNGRLGVWFETKLTRE MUL_4858|M.ulcerans_Agy99 DTVVKVA-GKRVDTAAVARRISADPTVCDVAVEPHDGRLGVWFETERTRE Mvan_2578|M.vanbaalenii_PYR-1 NNVLKLSQGEFVTVSRLEAVFGNSPLVRQIYVYGNSARPYLLAVVVPTEA : :*: * : . : :. * : * . MSMEG_0402|M.smegmatis_MC2_155 TA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAP TH_3730|M.thermoresistible__bu TA----DPVQARAQLADRLPPYMVPAAIVVLESIPLTSNNKLDVRALPAP MAB_4691c|M.abscessus_ATCC_199 TA----DCGGLRMAIADRLPAYMVPAAVVRLDAIPLTVNGKLDTRALPAP MAV_3239|M.avium_104 TA----DPAELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAP MMAR_3097|M.marinum_M AV----DPVVVRGVLGQRLPGYMVPAAVVVVAGLPLTVNGKLDRRALPAP Mflv_2696|M.gilvum_PYR-GCK AAGEDVDLARVRERVAAALPDYMTPAGYVVLDEIPITAHGKIDRAALPLP Rv0101|M.tuberculosis_H37Rv GEQ---DAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRL Mb0104|M.bovis_AF2122/97 GEQ---DAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRL MLBr_01996|M.leprae_Br4923 GVD---DAAAATRSRLILASLGVSSFFVVGVPCIPRKPNGKIDRDNLLVM MUL_4858|M.ulcerans_Agy99 AAE---DGATAGRIGLALASLGVPAFFVVAVPSIPRKPNGKVDGARLHTL Mvan_2578|M.vanbaalenii_PYR-1 ALAGADAKAAVAESLQDVAKATGLQSYEIPRDFLLETTPFTLENGLLTGI : : . .:: * MSMEG_0402|M.smegmatis_MC2_155 EYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSM TH_3730|M.thermoresistible__bu EYRATGAEYRAPGTPLEGLLAGIFAEVLGVERVGVDDSFFDLGGDSILSM MAB_4691c|M.abscessus_ATCC_199 DYGDHG-RYRAPANAVEEVLADIYAQVLGLERVSVDDSFFDLGGDSILSM MAV_3239|M.avium_104 DY--AGGRYRAPGDAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSM MMAR_3097|M.marinum_M EYG-DGDRYRAPVGPVQEILAGIYAEVLGLERVGVEDSFFELGGDSLSAM Mflv_2696|M.gilvum_PYR-GCK EIT-TATDYREPQTETEQHLAQLFSELLGVARVGVDDSFFELGGHSLLAT Rv0101|M.tuberculosis_H37Rv PQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIG-PDSSLLGEGIGSLDLI Mb0104|M.bovis_AF2122/97 PQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIG-PDSSLLGEGIGSLDLI MLBr_01996|M.leprae_Br4923 PQLVDSVQNYAGSGEGAAGLAEIWSRHLGRAIL-PDSSLLDEGIGSVDLI MUL_4858|M.ulcerans_Agy99 PQLADAVPRDAEAGESAAGLARVWSCHLGRPLA-ADSSLLGAGIGSLDLI Mvan_2578|M.vanbaalenii_PYR-1 RKLARPRLRERYGEQLEALYTMLSEEQADELRELRRSGGERPALETVGRA : : . .. . :: MSMEG_0402|M.smegmatis_MC2_155 QVVARARAAGIQCRPRDIFVEQTVAGVARVAVAAG---ESHVVDEGVGPV TH_3730|M.thermoresistible__bu QVVARARAAGVQCRPRDIFVEQTVARLASVVKVSGG--EPETVDDGTGAV MAB_4691c|M.abscessus_ATCC_199 QVVSRGRAAGLLCRPRDIFVEQTVARLARVVQVTAG--SRGPIDEGLGHV MAV_3239|M.avium_104 QVVARARAAGVMCTARDVFVEQTVARLARVVTVAAADGELGAADEGIGPV MMAR_3097|M.marinum_M RLIAAVNAG----------------------------------------- Mflv_2696|M.gilvum_PYR-GCK KLVSAVRSR----------------------------------------- Rv0101|M.tuberculosis_H37Rv RILPETRRYLG--------------------------------------- Mb0104|M.bovis_AF2122/97 RILPETRRYLG--------------------------------------- MLBr_01996|M.leprae_Br4923 RILPDTRRHLG--------------------------------------- MUL_4858|M.ulcerans_Agy99 RILPDTRRYLG--------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 AGALLGTTAG---------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 VATPIMRWLREVDGPTGQFNQTVITQAPAG----VTEDDVVVILQALLDR TH_3730|M.thermoresistible__bu VATPIMRWLRGVDGPTDQFNQTVVLQAPPGTDTAAAEADVVAVLQALIDR MAB_4691c|M.abscessus_ATCC_199 VPLPIMLWLKGIDGPIEEFNQSVLVQAPEG----VAEDDVVTLLQSLLDR MAV_3239|M.avium_104 QPTPIMRWLQDIDGPIDEFNQTMVLAAPAG----VSQSDVAVVLQALLDR MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 HATLRLRVEDT--QEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEA TH_3730|M.thermoresistible__bu HPTLRMRAEGMTAGDGTDDWSLFIPEPGATSAREVMHTVDTLTDEVLIAA MAB_4691c|M.abscessus_ATCC_199 HAMLRLRVSGD----GVGGWSLTVPEPGSVDAATCLHTAEYLSDSAVVTA MAV_3239|M.avium_104 HPMLRLCLDDD----GAGGWDLHVPPPGSVDARPILRTVDVLSEAALARA MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 RNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQ TH_3730|M.thermoresistible__bu RSRLNPAAGVMLSAVWARGSGQLVLMIHHLAVDGVSWRILVEDLNIAWAQ MAB_4691c|M.abscessus_ATCC_199 RSRLDPAAGVMLSALWVTSTSQLVMIVHHLAVDGVSWRILLEDINLGWAQ MAV_3239|M.avium_104 RARLNPGAGLMLSAVWASETSQLALVVHHLAVDGVSWRTLIEDINIAWAQ MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 HCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALP TH_3730|M.thermoresistible__bu HRTGQPIDLPANGTSFARWSALLADHARAPEVVEHVEAWQRVIAAPSALP MAB_4691c|M.abscessus_ATCC_199 HRDGQSVVLPAAGTSFRRWAELLTALAHDPGVVEHARTWREVSAAPAIFP MAV_3239|M.avium_104 HHSGQEIALPVPGTSFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLP MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 PVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA TH_3730|M.thermoresistible__bu AIRPERDTYATAGQLSVSLDADTTRQLLGAVPAAFHAGVQDILLIAFGLA MAB_4691c|M.abscessus_ATCC_199 AVRPDTDTHETAGQLSVSLDVETTRMLLGAVPAAFHTGPQDILLIAFGLA MAV_3239|M.avium_104 AVGPD-DTYASAGQLSASLDVQTTRLLLGEVPAAFHAGVQDILLIAFGLA MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTV-E TH_3730|M.thermoresistible__bu WAEFLGACDSPIGIDVEGHGRAEELAAGVDLSRTVGWFTTKYPVALTI-P MAB_4691c|M.abscessus_ATCC_199 LAEFAAT-DTPIGIDVESHGRHEEIAAGIDLSRTVGWFTAKYPVSLSG-R MAV_3239|M.avium_104 CTEFVGG-GAPIGIDVEGHGRHEEIASGVDLSRTVGWFTTKYPVALRMSR MMAR_3097|M.marinum_M --------------------------LGVDLS------------------ Mflv_2696|M.gilvum_PYR-GCK --------------------------CGVDMEIR---------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 NLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSD TH_3730|M.thermoresistible__bu KLSWEQVRTGGDALGAAVKAAKEQLRSVPDGITYGLLRHLNPDVELGGAE MAB_4691c|M.abscessus_ATCC_199 GVRWSDVVAGNEALGAALKDAKEQLRGQPEGLTFGLLRYLNPGANLATSD MAV_3239|M.avium_104 RLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEIEVQGPD MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 PTIGFNYLGRLGAGAGELSEELWRIDQDSLALSDAASAVPMPLMHTVELN TH_3730|M.thermoresistible__bu PAIGFNYLGRLAAGAGDLPDELWRIDPSGLPITEAASKIPMPLAHTVEVN MAB_4691c|M.abscessus_ATCC_199 PTVGFNYLGRLAGGAAAMSDDLWRIPADGMSAVSVAAAIPMPLTHTVALN MAV_3239|M.avium_104 PVIGFNYLGRLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELN MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 AGTIDTD-NGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGG TH_3730|M.thermoresistible__bu AGTLDAGPDGPVLQATWTWAPSLVDEAQIARLSRLWFEALGGVCAHVRSG MAB_4691c|M.abscessus_ATCC_199 AGAVETD-DGPQLQANWTWASSALDRDQVSRLSQLWFDALTGICAHVRAG MAV_3239|M.avium_104 AGTMDTD-AGPQLHANWTWARSVLTDEQLNRLSRLWFEALTGICAHVQAG MMAR_3097|M.marinum_M ------------VRVLFEWP------------------TVAGLASCVGGV Mflv_2696|M.gilvum_PYR-GCK ------------------------------------EIFELGTVARLAER Rv0101|M.tuberculosis_H37Rv ---------------------------------------WRLSLLDLIGA Mb0104|M.bovis_AF2122/97 ---------------------------------------WRLSLLDLIGA MLBr_01996|M.leprae_Br4923 ---------------------------------------RHLSLLDLISA MUL_4858|M.ulcerans_Agy99 ---------------------------------------RHLSVLELISA Mvan_2578|M.vanbaalenii_PYR-1 --------------------------------------ELEPSAHFTDLG MSMEG_0402|M.smegmatis_MC2_155 GGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARG TH_3730|M.thermoresistible__bu GGGLTPSDIAPARLTQQQIDELADRHDIADILPLTPVQQGLLFHSAVTRT MAB_4691c|M.abscessus_ATCC_199 GGGLTPSDITPARLSQRQLDELQQQYLIADVLPLTALQQGLVFHSGAGNG MAV_3239|M.avium_104 GGGLTPSDIAPTRLDQGRIEQLERRYDVADILPLTPLQQGLLFHATGSHA MMAR_3097|M.marinum_M SGSVVP--VVPLVAGPR-----------PAVVPLSFTQSGLWFLEQVQ-- Mflv_2696|M.gilvum_PYR-GCK VDELAAGGSAPLRPRLLAVP-------HDGPAPMSAAQLRQWFQYRIE-- Rv0101|M.tuberculosis_H37Rv DTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQ Mb0104|M.bovis_AF2122/97 DTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQ MLBr_01996|M.leprae_Br4923 DNAANLT-------AAQTAN------------------------------ MUL_4858|M.ulcerans_Agy99 DTAANLVCDLGSNPAAPATD------------------------------ Mvan_2578|M.vanbaalenii_PYR-1 GDSLSALTFANLLRDIFDVD------------------------------ MSMEG_0402|M.smegmatis_MC2_155 IGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQ TH_3730|M.thermoresistible__bu TADDIYAVQLDLTIAGVVDQHRLRDAVHAVVARHPNLAARFCTDHDHPVQ MAB_4691c|M.abscessus_ATCC_199 PEGDLYVVQLDITIDGALEPERLHGAVHTVAARHPHLAARFCGQFEQPVQ MAV_3239|M.avium_104 EG-DVYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQ MMAR_3097|M.marinum_M GPSAVYNMAAAFRLGGGLDVDALGAAWVDVVGRHESLRTVFPAVGGVPQQ Mflv_2696|M.gilvum_PYR-GCK GPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHESLRTTFCEIDGVPYQ Rv0101|M.tuberculosis_H37Rv RPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQ Mb0104|M.bovis_AF2122/97 RPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQ MLBr_01996|M.leprae_Br4923 ---------------VWMDVGTAAEIERDLASLCRQR------------- MUL_4858|M.ulcerans_Agy99 ---------------GWLDAETAAAIERDLVSLGSQC------------- Mvan_2578|M.vanbaalenii_PYR-1 -------VPVGVIVSPATDLQALADYVESAR-RHGSVRPTFESVHGHSGR : MSMEG_0402|M.smegmatis_MC2_155 VLT--ADPMIAWRYLDLRGDD--LTPDHEIEQLCAAERSAVCDLLERPTF TH_3730|M.thermoresistible__bu IIP--TEPVAAWRYLDLRGDD--QNPEHEVQQLCAAERAAVRDLTERPTF MAB_4691c|M.abscessus_ATCC_199 LIP--AEPTVGWRYVDLSAEWNCADKDEELQRLCAAERAAVCDLTEPPAF MAV_3239|M.avium_104 IIP--AEPEIAWRYLELDASD----VDEQLEQLSADERAAVRELGDRPPF MMAR_3097|M.marinum_M VVVPVERADFGWRVVDAGG-----WSVGRLGEAVDAVAGYAFSLATEIPL Mflv_2696|M.gilvum_PYR-GCK LVN---APDPGFPVRRDSGPD-----DAWLVGALDDERRRVFDLENQWPI Rv0101|M.tuberculosis_H37Rv LVIEARRADLGCDIVDATAWP-----ADRLQRAIEEAARHSFDLATEIPL Mb0104|M.bovis_AF2122/97 LVIEARRADLGCDIVDATAWP-----ADRLQRAIEEAARHSFDLATEIPL MLBr_01996|M.leprae_Br4923 ---------------NATEFS-----VKQTRNSHQKQA------------ MUL_4858|M.ulcerans_Agy99 ---------------TPQPLG-----ADPPPHDRAAAP------------ Mvan_2578|M.vanbaalenii_PYR-1 PGT------------EVHARD------LTLDEFVDAAT------------ MSMEG_0402|M.smegmatis_MC2_155 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFG-------HR TH_3730|M.thermoresistible__bu RAALIRTGATEHRFVLTVHHIVIDGWSLPILLQEIFAGYFG-------QR MAB_4691c|M.abscessus_ATCC_199 RVALIRVAAERYRFVLTNHHIVLDGWSLPILLQEIFAAYRG-------QR MAV_3239|M.avium_104 GAALIRTADTEHRFVLTVHHLVMDGWSLPVLLQEIFACYYG-------AR MMAR_3097|M.marinum_M RAVLFRVSADEHVLVCVVHHIAGDGWSMTPLARDLGVAYAARCAGCVPGW Mflv_2696|M.gilvum_PYR-GCK RVAVLSIPG-EHALSVVVHHIAADHWSGGVLFTELLTAYRARRAGEAPTW Rv0101|M.tuberculosis_H37Rv RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDW Mb0104|M.bovis_AF2122/97 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDW MLBr_01996|M.leprae_Br4923 ------------IVVLGASGILGTGFAQAVLDLRQSGVLCP--------- MUL_4858|M.ulcerans_Agy99 ------------IVVLGASGIVGTGFARAVLQRKQAGLACP--------- Mvan_2578|M.vanbaalenii_PYR-1 --------------LAHAPTLPGPRAEVRTVLLTGATGFLG--------- : : MSMEG_0402|M.smegmatis_MC2_155 LPAAAPYRNFVNWLATQD---------ATAAKAAWREVLDGFETPTLVA- TH_3730|M.thermoresistible__bu LPAPARFRDFVTWLAAQD---------RDAARAAWRELLDGFDTPTLIA- MAB_4691c|M.abscessus_ATCC_199 LPAATPFRNFVSWLAARD---------TAAAQAAWGEVLAGFQTPTLVG- MAV_3239|M.avium_104 LPAPAPYRGFVTWLAARD---------VPAARAAWRAVLDGFDTPTLVA- MMAR_3097|M.marinum_M APLAVQYGDYTLWQRARLGDLGDEGSPIAAQLAYWQRVLAGMPERLALPT Mflv_2696|M.gilvum_PYR-GCK APLPVQYADYAAWQSALLAD---DSGIVAAQRRYWTQQLEGLSAETGLQP Rv0101|M.tuberculosis_H37Rv APLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT Mb0104|M.bovis_AF2122/97 APLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT MLBr_01996|M.leprae_Br4923 -----------------------------------EVVLA---TRARLPE MUL_4858|M.ulcerans_Agy99 -----------------------------------EIVLA---SRSKPPE Mvan_2578|M.vanbaalenii_PYR-1 -----------------------------------RYLALEWLERMALVG MSMEG_0402|M.smegmatis_MC2_155 --PPGVP--GPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLL TH_3730|M.thermoresistible__bu --PPGQA--GPRGSASYRIDTETTAAIGELARTQRTTVNTVLQAAWAHLL MAB_4691c|M.abscessus_ATCC_199 --PPQKSGLGRRGVRTHQLSGRLTGALGELARAQHTTVNTVLQGAWALLL MAV_3239|M.avium_104 --PRGADAPGRRGVASFRMAAETTSAVSELARRRRTTVNTVLQAAWAQLL MMAR_3097|M.marinum_M DRPYPPVADHRGGRVGIDWSVGLQQQIARVAREHNATSFMVVQAALAVVL Mflv_2696|M.gilvum_PYR-GCK DLVRPSVPSGAADAVEFTLDAAIREKLVTLSREVGATEFMLLQAAVAVTL Rv0101|M.tuberculosis_H37Rv ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLL Mb0104|M.bovis_AF2122/97 ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLL MLBr_01996|M.leprae_Br4923 GDPWTALQGVDG-------------------------------------- MUL_4858|M.ulcerans_Agy99 HGPWSALRDLEG-------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 GKLICLVRAKDDAAARVRLDSTFDSGDPELLRHYR--------------- MSMEG_0402|M.smegmatis_MC2_155 MRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGD TH_3730|M.thermoresistible__bu MAMTGQRDVVFGTAVSGRPADLPGADRIVGLLINTIPVRARIGADTTVAD MAB_4691c|M.abscessus_ATCC_199 TSLTGQQDVVFGSVVSGRPADVPGAESMVGLLINTVPVRANISAATTTAG MAV_3239|M.avium_104 MMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRARAAAATTIAD MMAR_3097|M.marinum_M AKISASSEVAVGVPVAGR--GDRGLDELVGMFVNTLVLRVDMSADPTVAD Mflv_2696|M.gilvum_PYR-GCK YKAGEGPDIPLGTPVAGR--TESELDQLIGFFINILVLRNDLRDNPSLRD Rv0101|M.tuberculosis_H37Rv SKLSGSPDVAVGFPIAGR--SDPALDNLVGFFVNTLVLRVNLAGDPSFAE Mb0104|M.bovis_AF2122/97 SKLSGSPDVAVGFPIAGR--SDPALDNLVGFFVNTLVLRVNLAGDPSFAE MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 LLRQLQSHHNDTLEHEHLALNDIHHVSG------HEQLFDTLFLYESYP- TH_3730|M.thermoresistible__bu LLAQLQHAHNDTLEHEHLALTEIHHLAG------HDQLFDTLFLYESYP- MAB_4691c|M.abscessus_ATCC_199 LLDQLTKEHAKTLEHQHVPLSEIHRIAE------QERLFDTLFVFENYP- MAV_3239|M.avium_104 LLDQLQCAHNDTVEHQHLGLNEIHRVTG------QDQLFDTLLVYENYP- MMAR_3097|M.marinum_M LLAQVRASSLDAYEHQDVPFEVLVERLNPVRSLTHHPLVQVMLAWQNFPG Mflv_2696|M.gilvum_PYR-GCK VGFRSREMALAAYAHQDLPFDQVVDAVS---------------------- Rv0101|M.tuberculosis_H37Rv LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPV Mb0104|M.bovis_AF2122/97 LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPV MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ----IDTSAFMGVQELAVTEFNN----REYNHYPLSVMALPGHELGLR-- TH_3730|M.thermoresistible__bu ----IDTGAFSGAQELAVTGFTN----REFNHYPLSVMALPGHELGLR-- MAB_4691c|M.abscessus_ATCC_199 ----VDTGVLSGADGFAIDEIIS----HESTDYPLTMQAIPGGELRLR-- MAV_3239|M.avium_104 ----IDTAALSAADDLTATEFSC----HDYNHYPLSLQVVPGDELGLR-- MMAR_3097|M.marinum_M QLSDPGSGLVLGDVQVTAVPVDTGSARIDLAFFVGERWTEAGEPAGIGGG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv GQLNLGDLQATPMPIDTRTARMD------LVFSLAERFSEGSEPAGIGGA Mb0104|M.bovis_AF2122/97 GQLNLGDLQATPMPIDTRTARMD------LVFSLAERFSEGSEPAGIGGA MLBr_01996|M.leprae_Br4923 ----------------VRIERIS------FENGPGE-------------- MUL_4858|M.ulcerans_Agy99 ----------------IRIEQLG------AALDAAD-------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLD TH_3730|M.thermoresistible__bu IEYDTEVFDTAAIDALADRFRRVLESMVGDPARRLSAIEVLDAAEREQLD MAB_4691c|M.abscessus_ATCC_199 IEYDTALFDVCGIETFVKRIESVLSAMVADPRRPLSAVQILDETERDRLQ MAV_3239|M.avium_104 LEFDTDVFDPAAIDTLADRLRRLLAAMPADPDRPLRSLDLLDSTEHTRLQ MMAR_3097|M.marinum_M VEFRTDVFDAGSIEMLIERLGRVLVAMTGDVGVRVSSLDVLDSVERVRLD Mflv_2696|M.gilvum_PYR-GCK ------------------------------PVRSLSRNPLFGVVVHVREE Rv0101|M.tuberculosis_H37Rv VEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLD Mb0104|M.bovis_AF2122/97 VEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLD MLBr_01996|M.leprae_Br4923 ------------LEALIR-----------------------DTDAGTLVN MUL_4858|M.ulcerans_Agy99 ------------LDALIR-----------------------DTGARSLIN Mvan_2578|M.vanbaalenii_PYR-1 ------------------------------------------RLAADHLE : MSMEG_0402|M.smegmatis_MC2_155 EWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEA TH_3730|M.thermoresistible__bu AWSNRAVLADSP-ALESIPEVFARQVARDPGAVAVTFEGRSMTYGELDDA MAB_4691c|M.abscessus_ATCC_199 RWGNQGVLTHLA-QPASIPELFARQVTRSPKSIALVCEDRSLTYLALDEA MAV_3239|M.avium_104 RWGNRPALSRPA-TGPSLPELFTAQVANAPHAVALRCAGRSMTYRELDEA MMAR_3097|M.marinum_M GWGNRAVLGASVPVGVSIPALFDAQVVRDRDAVALSFEGQSLTYGELDEA Mflv_2696|M.gilvum_PYR-GCK LPQDRVIATGSD-------------------------------------- Rv0101|M.tuberculosis_H37Rv EWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEA Mb0104|M.bovis_AF2122/97 EWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEA MLBr_01996|M.leprae_Br4923 GVGNTNMLVP---------------------------------YRELRLA MUL_4858|M.ulcerans_Agy99 CIGNTNVLVP---------------------------------YRGLRAA Mvan_2578|M.vanbaalenii_PYR-1 VIAGDKADADLG-------------------------------------- . MSMEG_0402|M.smegmatis_MC2_155 ANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSV TH_3730|M.thermoresistible__bu ATELANLLAVYGAGPGESVALLMPRSADAIVAILAVLKTGAAYLPIDPAV MAB_4691c|M.abscessus_ATCC_199 SNRLARFLIGRGVGPGERVALMFPRSAEAVVAILAVLKTGAAYLPIDPAL MAV_3239|M.avium_104 STRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLPIDPAL MMAR_3097|M.marinum_M SNRLARFLVGLGAGPGQRVALVFGRCAQAVTAILAVLKTGAAYVPIDPGL Mflv_2696|M.gilvum_PYR-GCK --------------------------------------GETTFTALEPTF Rv0101|M.tuberculosis_H37Rv SNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPAN Mb0104|M.bovis_AF2122/97 SNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPAN MLBr_01996|M.leprae_Br4923 N--------------VELVSAIVDICASYSTRLVHLS------------- MUL_4858|M.ulcerans_Agy99 N--------------VELVSTVAQVCAQRDVRLVHLS------------- Mvan_2578|M.vanbaalenii_PYR-1 ---------------------LDARTWQRLADTVDLIVDPAALVNHVLPY MSMEG_0402|M.smegmatis_MC2_155 PAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTL TH_3730|M.thermoresistible__bu PAARLEFMLSDAEPIVALTTVELGTRFNGTGVPIIEVDDPAPPMYPSSTL MAB_4691c|M.abscessus_ATCC_199 PGARVEFMVSDAGPMAVVTTAALAERFSGFGLPVVDVQDPAIAAECGAGL MAV_3239|M.avium_104 PATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVAATG--AQPGGPL MMAR_3097|M.marinum_M PAARVQFMVADAGPVAVVTTGGWGAGLDGCGCVVVDVADAGVEACAGTGL Mflv_2696|M.gilvum_PYR-GCK DMAHADLSVN---------------------------------------- Rv0101|M.tuberculosis_H37Rv PPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDAL-AAYPGTPP Mb0104|M.bovis_AF2122/97 PPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDAL-AAYPGTPP MLBr_01996|M.leprae_Br4923 -----SFVVNADVTVPQVTDPRE------------------------TPY MUL_4858|M.ulcerans_Agy99 -----TFVISADVTAPRVTDPRM------------------------SPY Mvan_2578|M.vanbaalenii_PYR-1 RQLFAPNVLGTAELLRIALTTRMKP------------------------- : MSMEG_0402|M.smegmatis_MC2_155 LTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVW TH_3730|M.thermoresistible__bu LPPAPDDIAYLIYTSGTTGVPKGVAITHANVTRVLHTLPADLPAGPGKVW MAB_4691c|M.abscessus_ATCC_199 TMPSADGMAHIIYTSGTTGLPKGVAVTQRNVTQLFDSLQIGVPLEPGQVW MAV_3239|M.avium_104 PPPAPDNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPG--TGVW MMAR_3097|M.marinum_M VAPAADDIAYLIYTSGTTGTPKGVAITHRNVTQLVASTDAGVPWGPEQVW Mflv_2696|M.gilvum_PYR-GCK ------------FFAGGNG------------------------------- Rv0101|M.tuberculosis_H37Rv PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSA--AQVW Mb0104|M.bovis_AF2122/97 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSA--AQVW MLBr_01996|M.leprae_Br4923 PYAASKSLAELVVAG----SPSALDFTIVRLPRVLG-------------- MUL_4858|M.ulcerans_Agy99 PYAASKSLAELIVAA----SSPVLDFTIVRLPRVLG-------------- Mvan_2578|M.vanbaalenii_PYR-1 -------FVYVSTIGVGAGIEPARFTEDADIRQISATRR----------- . MSMEG_0402|M.smegmatis_MC2_155 SQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNV TH_3730|M.thermoresistible__bu SQWHSLVFDVSVWEIWGALLHGGRLVIVPESITGSPDDLHDLLVAEHVDV MAB_4691c|M.abscessus_ATCC_199 TQFHSYSFDFSVWEIWGALLHGGRLVVVPETIARSSRDFHRLLVREQVTV MAV_3239|M.avium_104 SQCHSYGFDVSVQEIWGALAGGGRLVVVPESVTSSPDELHALLIAENVTV MMAR_3097|M.marinum_M TQWHSYSFDISGWEIWGALLHGGRLVVVPEQVVGSPEDFHALLVAERVTV Mflv_2696|M.gilvum_PYR-GCK --------------------YRGHVIYRTELYTR---------------- Rv0101|M.tuberculosis_H37Rv SQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSV Mb0104|M.bovis_AF2122/97 SQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSV MLBr_01996|M.leprae_Br4923 ------------------------------------EDYQ--LRNSSDIL MUL_4858|M.ulcerans_Agy99 ------------------------------------EDYQ--LRESADIL Mvan_2578|M.vanbaalenii_PYR-1 ------------------------------------------IDDSYANG MSMEG_0402|M.smegmatis_MC2_155 LYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTE TH_3730|M.thermoresistible__bu VYQTPSAAGMLSQRGLDSTALVVAGEACPTDLVDRWAPGRVMINAYGPTE MAB_4691c|M.abscessus_ATCC_199 LTQTPSAVSMLPVDGLDVATLVIGAEPCSPELVDRWAPGRTMVNVYGPTE MAV_3239|M.avium_104 LSQTPSALAALSPRNLH-AALVIGGEPCPAALADRWAPGRVMINAYGPTE MMAR_3097|M.marinum_M LSQTPTAAGVLSPQGLESVALLVGGEGCPGEVVDRWAPGRLMINEYGPTE Mflv_2696|M.gilvum_PYR-GCK ---------------------------ATAERFAGWLSAVITAFADDPER Rv0101|M.tuberculosis_H37Rv LTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTE Mb0104|M.bovis_AF2122/97 LTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTE MLBr_01996|M.leprae_Br4923 LSIVDACIALRAYPSATVTEEVTTGRAAAKAILG---------------- MUL_4858|M.ulcerans_Agy99 VSVVDACMALRSFPTLTLTEEVTTGRAAAQAILG---------------- Mvan_2578|M.vanbaalenii_PYR-1 YGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTR- . MSMEG_0402|M.smegmatis_MC2_155 STIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLA TH_3730|M.thermoresistible__bu TTMCVAISAPLTPGSGAVPIGTPVPRAALFVLDSWMRPVPAGVIGELYVA MAB_4691c|M.abscessus_ATCC_199 TTMWLCASAPLAPGLGAPPIGSPTAWAAFFVLDEWLRPVPAGVVGELYLG MAV_3239|M.avium_104 TTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGWLRPVPAGVTGELYIA MMAR_3097|M.marinum_M TTMWVALSAPLVAGSGAPPIGSPVSGAALFVLDGWLRPVPVGVVGELYVA Mflv_2696|M.gilvum_PYR-GCK HVDDVVIAEPVRPG----------DGAEAVLLDGAGHPVPVGVVADVHYA Rv0101|M.tuberculosis_H37Rv TTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIA Mb0104|M.bovis_AF2122/97 TTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIA MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 GRGVGVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLG TH_3730|M.thermoresistible__bu GDGVAVGYVGRSELTASRFVACPFGPPGSRMYRTGDLVRWGADGQLQYLG MAB_4691c|M.abscessus_ATCC_199 GAGVGIGYWRRSGLTAARFMACPFGEPGSRMYRTGDLVRWRADGQLDYLG MAV_3239|M.avium_104 GAGVAAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLHYVA MMAR_3097|M.marinum_M GVGVGVGYWGRGSLTGSRFVACPFGGVGERMYRTGDLVCWGRDGQLQYRG Mflv_2696|M.gilvum_PYR-GCK GAPD----------------------------RRGDRARWTEDGRLQYVE Rv0101|M.tuberculosis_H37Rv GAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLG Mb0104|M.bovis_AF2122/97 GAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLG MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 RADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARED----RPGDKRLV TH_3730|M.thermoresistible__bu RADEQVKIRGYRIELGEVQTALTAVDGVENAVVIARED----RPGDKRLV MAB_4691c|M.abscessus_ATCC_199 RADEQVKIRGYRIELGEIQSALAALDGVENAAVIARED----RPGDKRLV MAV_3239|M.avium_104 RADQQVKIRGHRIELGEIHSALAELDGVEQAAVIARED----RPGEKRIV MMAR_3097|M.marinum_M RVDDQVKVRGYRIELGEVQAALGAVDGVGQAVVVVRED----RGGDRRLV Mflv_2696|M.gilvum_PYR-GCK RVDH------------DLEAALAAVPGVAAAAVRTWEIG--HRTAVVGYV Rv0101|M.tuberculosis_H37Rv RTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYAT Mb0104|M.bovis_AF2122/97 RTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYAT MLBr_01996|M.leprae_Br4923 -----------------VVSALARSGQLGSGISVVRG---EAVAYADFLS MUL_4858|M.ulcerans_Agy99 -----------------LLPQFSGAAGLGHGITVVRG---AAVQYRELLS Mvan_2578|M.vanbaalenii_PYR-1 ----------------LIFSLVATGVAPESFYHLATDGTRQRAHYDGLPV : . . . MSMEG_0402|M.smegmatis_MC2_155 GYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA TH_3730|M.thermoresistible__bu GYITGTADPDQARARLADRLPAYMVPTAVVVLDALPLTVNGKLDTRALPA MAB_4691c|M.abscessus_ATCC_199 GYITGAADPVGARTALAERLPGYMVPAAVVGLAALPMTVNGKLDVRALPA MAV_3239|M.avium_104 GYLTGTADPAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPA MMAR_3097|M.marinum_M GYVTGAVDPVVVRGVLGQRLPGYMVPAAVVVVAGLPLTVNGKLDRRALPA Mflv_2696|M.gilvum_PYR-GCK VPAEPVDDPASFAETVRAAVAPESAPTSITVLDALPATRRALPAPRVGGP Rv0101|M.tuberculosis_H37Rv EIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPA Mb0104|M.bovis_AF2122/97 EIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPA MLBr_01996|M.leprae_Br4923 EFASDELNMAEWKYRLDQ-------------------------------- MUL_4858|M.ulcerans_Agy99 GYALDEIDAAEWKHRLDQ-------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 EFIAEAISTLGSDVASGFRTYHVMNP------------------------ . MSMEG_0402|M.smegmatis_MC2_155 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDSISAM TH_3730|M.thermoresistible__bu PEYQDAEQYRAPTHAVEEVLAGIYAEVLGIDKVGVDDSFFDLGGDSISSM MAB_4691c|M.abscessus_ATCC_199 PDYQDVDRYRAPVGAVQEILAGIYARVLDVERVGVDDSFFDLGGDSVSTM MAV_3239|M.avium_104 PEYAGG-AYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAM MMAR_3097|M.marinum_M PEYGDGDRYRAPVGPVQEILAGIYAEVLGLERVGVEDSFFELGGDSLSAM Mflv_2696|M.gilvum_PYR-GCK SEPARTDTEKALVG----MLADVLVEVHDGTGIGRFDDFFELGGDSILAV Rv0101|M.tuberculosis_H37Rv PEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM Mb0104|M.bovis_AF2122/97 PEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM MLBr_01996|M.leprae_Br4923 SDWAKRN----------------------PRRWSVIDAWFTLG------M MUL_4858|M.ulcerans_Agy99 SDWARRN----------------------PQRWSVVDAWVSLG------M Mvan_2578|M.vanbaalenii_PYR-1 ----------------------------HDDGIGLDEYVDWLIDAGHPIR . : * MSMEG_0402|M.smegmatis_MC2_155 RVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSF----- TH_3730|M.thermoresistible__bu QVVARAR-AAGLTIRPRDIFVERTVARLAQVAVPTG-------------- MAB_4691c|M.abscessus_ATCC_199 RLVAAVNAALNADLSTRTVFDAPTIAQLALRIGEGAGGPEPLVVVER--- MAV_3239|M.avium_104 RVIAAVNAGLDARLSVRVLFEAPTIAQLAARLGEGGHRFAAVVAAER--- MMAR_3097|M.marinum_M RLIAAVNAGLGVDLSVRVLFEWPTVAGLASCVGGVSGSVVPVVPLVAGPR Mflv_2696|M.gilvum_PYR-GCK QLAARAK-QAGLRLSARMVFEHPVVHDLAVAL------------------ Rv0101|M.tuberculosis_H37Rv RVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSV--- Mb0104|M.bovis_AF2122/97 RVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSV--- MLBr_01996|M.leprae_Br4923 MFEMRSY----AEYPTMALG------------------------------ MUL_4858|M.ulcerans_Agy99 RLGARSYSQYLAGYPSIPLQ------------------------------ Mvan_2578|M.vanbaalenii_PYR-1 RVGDYPTWLQRFTVAITALPERQR-------------------------- . : MSMEG_0402|M.smegmatis_MC2_155 -----------------------------AAVHGSDVTEVHARDLTLDKF TH_3730|M.thermoresistible__bu -------------------------------------ADAAVDDAGTGPV MAB_4691c|M.abscessus_ATCC_199 PEVIPLSFAQNRLWFVDQLQGPSPVYNMPVGLRLYGRLDAAALGAALSDL MAV_3239|M.avium_104 PAVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDV MMAR_3097|M.marinum_M PAVVPLSFTQSGLWFLEQVQGPSAVYNMAAAFRLGGGLDVDALGAAWVDV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ID-APTLRTATTLPR----------------------------------- TH_3730|M.thermoresistible__bu VA-TPIMRWLYDTRG----------------------------------- MAB_4691c|M.abscessus_ATCC_199 IGRHESLRTRFDAPGGNPRQIVLPDGPIDFGWEIIDATSWQTGQLDEAIA MAV_3239|M.avium_104 VTRHESLRTVFAATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDVIR MMAR_3097|M.marinum_M VGRHESLRTVFPAVGGVPQQVVVPVERADFGWRVVDAGGWSVGRLGEAVD Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ATVCRSFDLAIEIPLYARVFRIAEEEHVLVAVVHHIAADGWSLTPLMHDL MAV_3239|M.avium_104 DTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPLVRDL MMAR_3097|M.marinum_M AVAGYAFSLATEIPLRAVLFRVSADEHVLVCVVHHIAGDGWSMTPLARDL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ------------------PDGAVQTVLLTGATGFLGRYLLLEWLRQLRRV TH_3730|M.thermoresistible__bu ------------------PIDQFNQTVVLRAP------------------ MAB_4691c|M.abscessus_ATCC_199 SVAYASRCRGHAPDWAPLPVQYVDYTLWQRAQLGDLGDGDSPISAQLAYW MAV_3239|M.avium_104 ARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYW MMAR_3097|M.marinum_M GVAYAARCAGCVPGWAPLAVQYGDYTLWQRARLGDLGDEGSPIAAQLAYW Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------HGDNPTE Mb0104|M.bovis_AF2122/97 -------------------------------------------HGDNPTE MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 DDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQVVAGDKG TH_3730|M.thermoresistible__bu --------AGVTEADVVEILQAVLDRHAMLRLRAADVENLTVPESGAVTA MAB_4691c|M.abscessus_ATCC_199 EGALAGLPERVALPTDRPYPPVADQRGSTVEVQWPPELQQQVRATAREHG MAV_3239|M.avium_104 ESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHN MMAR_3097|M.marinum_M QRVLAGMPERLALPTDRPYPPVADHRGGRVGIDWSVGLQQQIARVAREHN Mflv_2696|M.gilvum_PYR-GCK --------------DTAKTPEVADVRHDPMSASGLTPEELAMVATSWAAE Rv0101|M.tuberculosis_H37Rv VHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLEL Mb0104|M.bovis_AF2122/97 VHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLEL MLBr_01996|M.leprae_Br4923 ----------------VESVAELAAPPESIRALLAHGCSQPLKYTGR--- MUL_4858|M.ulcerans_Agy99 ----------------VGTVAEIAAPPTALRALLEQGCAQPPRPALA--- Mvan_2578|M.vanbaalenii_PYR-1 --------------QASLLPLLHNYQHPETPIRGSIAPTDRFREAVQDAK MSMEG_0402|M.smegmatis_MC2_155 QPNLGLDEQTWQRLAESVDLIVDSAAFVNSV------------------- TH_3730|M.thermoresistible__bu RGCLRTVHRLSGDELRSARAELDPAAGT---------------------- MAB_4691c|M.abscessus_ATCC_199 ATSFMVMQASLAVLLASISGTSDVAVGFPIAGRRDTALDQLVGFFVNNLV MAV_3239|M.avium_104 ATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLV MMAR_3097|M.marinum_M ATSFMVVQAALAVVLAKISASSEVAVGVPVAGRGDRGLDELVGMFVNTLV Mflv_2696|M.gilvum_PYR-GCK QDGSP--------------------------------------------- Rv0101|M.tuberculosis_H37Rv LRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLE Mb0104|M.bovis_AF2122/97 LRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLE MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 IGPDKDIPHVTPQIVIKYVTDLQRLGLL---------------------- MSMEG_0402|M.smegmatis_MC2_155 ----------------------------------LPYSELFGPNVVGTAE TH_3730|M.thermoresistible__bu -----------------------------------MVRALWAPDTR---- MAB_4691c|M.abscessus_ATCC_199 LRVDLSGDPTVAELLTQVRQRSLAAYENQDVPFEVLVERLNPIRSLAHHP MAV_3239|M.avium_104 LRVDVSGDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHP MMAR_3097|M.marinum_M LRVDMSADPTVADLLAQVRASSLDAYEHQDVPFEVLVERLNPVRSLTHHP Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv VVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAG Mb0104|M.bovis_AF2122/97 VVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAG MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 LIRFALTSKLKPFNFVSTSD------------------------------ TH_3730|M.thermoresistible__bu --RLALIVHHLAVDAVS--------------------------------- MAB_4691c|M.abscessus_ATCC_199 LVQVALAWQNLPWQDTGPADGLRLGDLRVEPLSVDTQTARMDLTFSLGER MAV_3239|M.avium_104 LVQVMLAWQNIEPTELSLGQVR------VIPLPVDTRTARMDLAWSLAER MMAR_3097|M.marinum_M LVQVMLAWQNFPGQLSDPGSGLVLGDVQVTAVPVDTGSARIDLAFFVGER Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv TAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDG Mb0104|M.bovis_AF2122/97 TAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDG MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ----------VGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGN----- TH_3730|M.thermoresistible__bu --------------------------------WRILVEDIN--------- MAB_4691c|M.abscessus_ATCC_199 WTMAGEPAGIAGAVEFRTDVFDADSIEALIARWQRVVASMTADPSRRLSS MAV_3239|M.avium_104 WTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTADPGRRLSS MMAR_3097|M.marinum_M WTEAGEPAGIGGGVEFRTDVFDAGSIEMLIERLGRVLVAMTGDVGVRVSS Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv GWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSD Mb0104|M.bovis_AF2122/97 GWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSD MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ------------SKWAGEVLLREA--------HDHCGLPVAVFRSGMIMV TH_3730|M.thermoresistible__bu ------------IAWG----------------QRHTGQPIDLPAG----- MAB_4691c|M.abscessus_ATCC_199 IDVLDEAEHTRVDRWGNRELLNRPPAVRRSVPALFAEQAARVPHAVAISF MAV_3239|M.avium_104 IDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQVARTPHAVALTA MMAR_3097|M.marinum_M LDVLDSVERVRLDGWGNRAVLGASVPVGVSIPALFDAQVVRDRDAVALSF Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv WVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGA Mb0104|M.bovis_AF2122/97 WVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGA MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 DPTYAGQLNVTDTVSRMVLSIVATGVAPG------------------SFY TH_3730|M.thermoresistible__bu ----------GTSFARWSTLLAEYADTPE------------------VVA MAB_4691c|M.abscessus_ATCC_199 NGRELTYREVDQASDQLAHRLIAQGVRPGESVALLTERCPEAVVAMLAVL MAV_3239|M.avium_104 NGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAILGVL MMAR_3097|M.marinum_M EGQSLTYGELDEASNRLARFLVGLGAGPGQRVALVFGRCAQAVTAILAVL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv RVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQ Mb0104|M.bovis_AF2122/97 RVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQ MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 QRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVM TH_3730|M.thermoresistible__bu QAG-----------------VWQQVAAXXWPSCSTPTTTSSS---TSTWR MAB_4691c|M.abscessus_ATCC_199 KTGAAYLPIDPALPDVRVEFMIGDAAPTAAITTADLTDRLAGYALTVIDV MAV_3239|M.avium_104 KAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDV MMAR_3097|M.marinum_M KTGAAYVPIDPGLPAARVQFMVADAGPVAVVTTGGWGAGLDG--CGCVVV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv RFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAV Mb0104|M.bovis_AF2122/97 RFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAV MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 NPHDDGIGIDTYIDWLIEAGYPIERIEDFG-------------------- TH_3730|M.thermoresistible__bu STRSTGRPVRTGCSTRCSS---TRTIRSMR-------------------- MAB_4691c|M.abscessus_ATCC_199 GDIAEGASSGAGSSLPLPSPDDIAYIIYTSGTTGVPKGVAIAHHNVTALM MAV_3239|M.avium_104 DDPSIRE--QPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLF MMAR_3097|M.marinum_M DVADAGVEACAGTGLVAPAADDIAYLIYTSGTTGTPKGVAITHRNVTQLV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv RAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL--------------- Mb0104|M.bovis_AF2122/97 RAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL--------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GSPATF----LAGHTWAQWHSYAFDASVEEIWGSLLHGGRLVVVPESAAH MAV_3239|M.avium_104 ASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGALLNGGRVLVVPDDVVR MMAR_3097|M.marinum_M ASTDAG-LPRGPEQVWTQWVSYSFDVSVWEIWGALLSGGRLVVVPEQVVG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 SPEHLTALLVAEQVTALSQTPSAVALLTPESLDAVSLLVAGEP------- MAV_3239|M.avium_104 SPEDLCALLIDEHVDVLSQTPSAFDALQRADSARRLNPQTVIFGGEALIP MMAR_3097|M.marinum_M SPEDFHALLIAERVTVLSQTPTTAGVLSPQGLDSVALLMGSEACP----- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------EWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGEL--QPPVP TH_3730|M.thermoresistible__bu -------RRWPGRKALRSPISRAANTTTIRCRWSQCPGTSSDC--ASNTT MAB_4691c|M.abscessus_ATCC_199 -CPGEVVDRWAPGRLMVNAYGPTETTICASRTAALVGGTGSPS--IGAPV MAV_3239|M.avium_104 HRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSPIGMPL MMAR_3097|M.marinum_M ---GEVVDRWAPGRLMINGYGPTETTIYTTLSAPLVAGSGAPP--IGSPV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 TRGSFAPAD------------RFQAAVRDANIGVEGEIPHVTREVIVKYV TH_3730|M.thermoresistible__bu PRCSTPRMS------------RHWSAGCGGC------------------- MAB_4691c|M.abscessus_ATCC_199 PGAAMFVLDGLLRPVPPGVVGELYIAGHGVGVGYAGRTGLTASRFVACPF MAV_3239|M.avium_104 AHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPF MMAR_3097|M.marinum_M SGAALFVLDGWLRPVPVGVVGELYVAGVGVGVGYWGRGSLTGSRFVACPF Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 TDLQLLGLL----------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ADAQLPGQRMYRTGDLVRWRADGQLEYLGRADEQVKIRGYRIELAEIHSV MAV_3239|M.avium_104 GG---AGERMYRTGDLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSA MMAR_3097|M.marinum_M GG---VGERMYRTGDLVCWGRDGQLQYRGRVDDQVKVRGYRIELGEVQAA Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LTALDGVDQAAVIAREDRPGDRRLVGYVTGTANPAKLRAQLAEQLPAYMV MAV_3239|M.avium_104 LAELDGVEQATVIAREDRPGDKRLVGYVTGTADPAQLRTALAERLPAYLV MMAR_3097|M.marinum_M LGAVDGVGQAVVVVREDRGGDRRLVGYVTGAVDPVVVRGVLGQRLPGYMV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 PVAVVVLAALPMTVNGKLDTRALPRPEYQDIDRYRAPGTLTEEILAGIYA MAV_3239|M.avium_104 PAAVVAIDAMPLTPNGKLDTGALPAPDYHGADQYHAPASAVEQTLADIYA MMAR_3097|M.marinum_M PAAVVVVAGLPLTVNGKLDRRALPAPEYGDGDRYRAPVGPVQEILAGIYA Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RVLGVER---VGVDDSFFDLGGDSLSAMRLIAAVNADLNAVVSVRTVFEA MAV_3239|M.avium_104 HVLDVRPPRLVGIDDSFFDLGGDSLSAMRLVAEVNSRLDVHLGVRALFEA MMAR_3097|M.marinum_M EVLGLER---VGVEDSFFELGGDSLSAMRLIAAVNAGLGVDLSVRVLFEW Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 PTVGQLAPRIADAS---SSLSPLVAAERPAQIPLSFAQARLWFLDQLQGP MAV_3239|M.avium_104 PTIRRLAARLGADG---SARAPLVAAERPAVVPLSFAQSRLWFIGQLHGP MMAR_3097|M.marinum_M PTVAGLASCVGGVSGSVVPVVPLVAGPRPAVVPLSFTQSGLWFLEQVQGP Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 SPVYNMATALRISGALDVDALGAGLADVVARHESLRTQFRATGGVPQQVV MAV_3239|M.avium_104 SPVHNMAIALQLHGRLDAAAFGAALADVVGRHESLRTLFPAHEGIPQQLV MMAR_3097|M.marinum_M SAVYNMAAAFRLGGGLDVDALGAAWVDVVGRHESLRTVFPAVGGVPQQVV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VPAADAHFGWDVVDATGWTTSQLREAIGEAARHTFDLSNEIPLYARLFRI MAV_3239|M.avium_104 IEVDEADIGWQVIDASGWSPARLDDVIRDTARHTFDLAAEIPLRAVLLRC MMAR_3097|M.marinum_M VPVERADFGWRVVDAGGWSVGRLGEAVDAVAGYAFSLATEIPLRAVLFRV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TGDEYVLAAVVHHIAADAWSITPLVTDLGVAYVSRRAGHAPGWAPLAVQY MAV_3239|M.avium_104 GDEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQY MMAR_3097|M.marinum_M SADEHVLVCVVHHIAGDGWSMTPLARDLGVAYAARCAGCVPGWAPLAVQY Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 VDYTLWQRAEFGDFADGGSRIAAQLDYWQDALAGMPERVELPTDRPYPST MAV_3239|M.avium_104 VDYTLWQRAQFGDLDDPHSLIAGQLRYWESALAGMPERLELPTDRPYPVV MMAR_3097|M.marinum_M GDYTLWQRARLGDLGDEGSPIAAQLAYWQRVLAGMPERLALPTDRPYPPV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 ADQRGSTMAVQWPAALQEQIARVAREHNATSFMVLQAALGVLLSKLSGNT MAV_3239|M.avium_104 ADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAALAVLLAKVSASS MMAR_3097|M.marinum_M ADHRGGRVGIDWSVGLQQQIARVAREHNATSFMVVQAALAVVLAKISASS Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DVAVGFPIAGRRDPALDELIGFFVNTLVLRLDLSGDPTVAELLAQVRARS MAV_3239|M.avium_104 DVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVSGDPTVAELLARVRQRS MMAR_3097|M.marinum_M EVAVGVPVAGRRDPALDDLVGLFHNTLVLRVDMSADPTVADLLAQVRASS Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LAAYENQDVPFEVLVERLNPTRSLTHHPLIQVALGWQNVPGQDNGSSGPG MAV_3239|M.avium_104 LAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQN-------IEPTE MMAR_3097|M.marinum_M LDAYENQDVPIEVLVERLNSNRSLTHSPLAQVVLTWLNFPGQQDNPAKG- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LALGDLEVTPMDADTQTARMDLSFSLAEHRTRDGEPAGIGGTVEFRTDVF MAV_3239|M.avium_104 LSLGQVRVIPLPVDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVF MMAR_3097|M.marinum_M LVLGDLEVTPMPVDTRTARTDALFSLAERWTETGEPAGIGGGVEFRTDVF Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DPASIERLLGRFELVLTAMTADVESRLSSIDVLDPAEHARLDSMGNRALL MAV_3239|M.avium_104 DTATVEALTQRLRRVLAAMTADPGRRLSSIDLLDPAEHARLDALGNRAVL MMAR_3097|M.marinum_M DAGSIEMLIERLGRVLVAMTGDVGVRVSSLDVLDSVERVRLDGWGNRAVL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 EQRAINPVTVPALFADQVARTPEAVAVTCGGHALTYRELDDAANWLALRL MAV_3239|M.avium_104 TRPQHPPTSIPEVFAAHVARTPHAVAVTCGRRSWTYRELDSSANRLAHLL MMAR_3097|M.marinum_M GASVPVGVSIPALFDAQVVRDRDAVALSFEGQSLTYGELDEASNRLARFL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 SRAGVVPGGCVALLLERSSQAIVAMLAVLKAGAAYLAIDPVMPSARIDFM MAV_3239|M.avium_104 IHHGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLPIDPSLPSARIEFM MMAR_3097|M.marinum_M VGLGAGPGQRVALVFGRCAQAVTAILAVLKTGAAYVPIDPGLPAARVQFM Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LDDAAPTAVVTTSGLAGRFDGREMSVIDIGELADVDDAEMEIVHSPANPG MAV_3239|M.avium_104 LTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPS------IREQPVTAPPA MMAR_3097|M.marinum_M VADAGPVAVVTTGGWGAGLDGCGCVVVDVADAG------VEACAGTGLVA Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 PEPDDIAYLIYTSGTTGVPKGVAVTHHNLTHLARSTPAQ---LPANQVWT MAV_3239|M.avium_104 PAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWG MMAR_3097|M.marinum_M PAADDIAYLIYTSGTTGIPKGVAVSHRNVVALVESLASS---VPVAGVWS Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 QCHSYAFDFSVWEIWAALLGGARVVVVPESIVSSPEDFHTLLVRERVNVL MAV_3239|M.avium_104 QCHSLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPKDLHALLVAERVDML MMAR_3097|M.marinum_M QWHSYAFDVSVCEIWGALLSGGRLVVVPEQVVGSPEDFLALLVAERVSVL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TQTPSAAGALS---------PAGLDSVALLLGGEACPGEVVDRWAAGH-- MAV_3239|M.avium_104 TQTPSEVGVLS---------PDGLESTTLAVAGEACPVEVVDRWAPGR-- MMAR_3097|M.marinum_M SQTPSAFYALQGAVAVRSGLGRELRVEAVLLAGEAFEPQRAGVWLARRPG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 --TVINAYGPTEITVYASMSAPL--AAGSGAAPIGAPVSTSALFVLDEWL MAV_3239|M.avium_104 --VMINVYGPTETTIVAAVSAPL--TPGPEAPPIGAPVPGTALRVLDAHL MMAR_3097|M.marinum_M LARLINLYGTTETTVHASVREIVGADADSAVSPIGVPLGHLGFFVLDGWL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RPVPVGVVGELYVAGEGVACGYLGRSGLTSARFVACPFGVPGARMYRTGD MAV_3239|M.avium_104 RPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGD MMAR_3097|M.marinum_M RPVPVGVVGELYVAGVGVGVGYWGRGSLTGSRFVACPFGGVGERMYRTGD Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LVSWRPDGQLQYRGRADDQVKIRGYRIELGEVQAALSALSDVSQAAVIAR MAV_3239|M.avium_104 LVRWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAR MMAR_3097|M.marinum_M LVCWGRDGQLQYRGRVDDQVKVRGYRIELGEVQAALGAVDGVGQAVVVVR Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 EDPPGVTRLVGYVTESVNGVAEPDRLRNALANRVPGYMVPSAIVVLEALP MAV_3239|M.avium_104 EDRPGDKRLVGYVTG----TADLAQLRTALAERLPGYMVPAAVLMLDALP MMAR_3097|M.marinum_M EDRGGDRRLVGYVTG----AVDPVVVRGVLGQRLPGYMVPAAVVVVAGLP Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LTVNGKLDIRALPAPEYQDAERYRAPADAVEETLAGIYAQVLGLDR-VGV MAV_3239|M.avium_104 LTPSGKLDTGALPAPDYQGPEGYLAPAGAVEEILAWLYAQVLGLPRRVGV MMAR_3097|M.marinum_M LTVNGKLDRRALPAPEYGDGDRYRAPVGPVQEILAGIYAEVLGLER-VGV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DDSFFDLGGDSILSMQVVARAR-ACGVVCRPRDIFVEQTVARLAQVVGVV MAV_3239|M.avium_104 QESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEAPSVRSLSQRLN-- MMAR_3097|M.marinum_M EDSFSELGGDSLSALRVIAKVNKALGLELPARTLRDAPSVRILSQRLHTS Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DEDSGPVDEGVGPVAATPIMRWLRDVEGTGAPTDQFNQTAVIQAPAGASE MAV_3239|M.avium_104 --ADPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAPALPG MMAR_3097|M.marinum_M DNGMEVVPVEILKEDTGVPLCCIHDGLG---------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 SDVEMVLGALLDRHAMLRLRVENWMLQVPEQTLTAPCLQSVEVLTDAELL MAV_3239|M.avium_104 PGAEVRTVLLTGATGFLG------------RYLVLQWLERLELADGKLIC MMAR_3097|M.marinum_M --------------------------------LSWSYRALGNYLDCPIIG Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AARARLNPAAGQMVSALWVASTGQLVLVIHHLAIDAVSWRILLEDLNIAW MAV_3239|M.avium_104 LVRAASDDDARRRLERTFDSGDPALLRYFHELAADHLEVIAGDKGR---- MMAR_3097|M.marinum_M INQIAENGEAEPESIRSMAANYADRLQATYPAGPYNLLG----------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GQHRHGQPVALPKAGTSFARWAALLEEHAYDRDVVDQTDRWRRVLATPPA MAV_3239|M.avium_104 --------ANLGLDDRTWQRLADTVDLIVDAAAVVNGVLPYQELFGPNVA MMAR_3097|M.marinum_M -----------------WSFGGVVAHELAIELHRRGCVVQRLILLDPPQL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LPAACPELDTYASAGHYTASLDVETTRALLGAVPAAFHAGVQDILLIGYA MAV_3239|M.avium_104 GTAELIRLALSTRLKPYSYVSTANVG------------------------ MMAR_3097|M.marinum_M PGSTLRSLGVEEDQ------------------------------------ Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LALTEFLGVTLPVGIEVEGHGRVEDLGGCVTEIDLSRTVGWFTTKYPVAL MAV_3239|M.avium_104 -DQIEPSAFTEDADIRVAGPIRTIDGG----------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AVSGKPGRSAGRLRWDQVVAGDPLLGAVIKDAKEQLRSLPEGMTYGLLRY MAV_3239|M.avium_104 --------------YGNGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMIL MMAR_3097|M.marinum_M ----------------IVDGSSRPNHAAIREQAEQLINQLREVVDFTALP Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 LNSDVDLTGAEPTVGFNYLGRLGGGGAGRAEFHDQLWQVSPDTAAVAAAV MAV_3239|M.avium_104 ADTSYAGQLNLPDMFTRLLFSVVASGVAPRSFYR----LDAHGNRQRAHF MMAR_3097|M.marinum_M SG------------------------------------IFDFAARNAKAV Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TALPMPLTHTVELNASTAETEDGPSLYAAWTWAPSVLDEVQAARLSRLWF MAV_3239|M.avium_104 DALPVEFVAEAIATLGAQVGRDAGTGFATYHVMNPHDDGIGLDEYVDWLI MMAR_3097|M.marinum_M QSYLLEHKADVFDGDMTIFLAGRSGQMSDSSQLQNWRNYIAGDITTYSVD Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 DALAGICAHVRSGGGGLTPSDIVPARLTQRELDDLARDHAIDDVLPLTPL MAV_3239|M.avium_104 DAGYPIERVDDFDQWLHRMETALHALSERQRHQSVLQLLALRNARHVPPA MMAR_3097|M.marinum_M CTHHEMLTAESLSMYGEQLKKLLEA------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 QHGLLFQANTSRGNSDDVYAMQLDITITGPLDADRLREAVRAVVNRHPNL MAV_3239|M.avium_104 DP-----ARGCLGPTERFRAAVQEAKIGADNDIPHITAPVIVKYVTDLQL MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 AARFDKRFDEPVQIIPANPTAPWQVVEIDVEQADYEQRLQGLCAAERAAV MAV_3239|M.avium_104 LGLL---------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 CDVVNQSAFRAALIRIDENEHRFVMTYHHIVLDGWSLPILLREVFASYYG MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 QRLPVASSYRRFVTWLIERDVDGARRAWCEVLKDFDRPALVAPKGRLPGR MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 RATETFRISADISDAVGQLARSQHTTANTVLQAAWAQVLMWLTGRHDVAF MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GVAVSGRSAEVAGADSMVGLLINTVPVRVTVTPDTTIAELLANLQRQHSD MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 TLEHQHLALSEIQHAVGQEQLFDTLFVYQNYPVQTMASSMPDGLSITAVS MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MAB_4691c|M.abscessus_ATCC_199 GREYNHYPLTLQAMPGNELVLRVEFDTGLFGESRVRKVVERFQRVLEAMT MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3097|M.marinum_M -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- Mvan_2578|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ---- TH_3730|M.thermoresistible__bu ---- MAB_4691c|M.abscessus_ATCC_199 GEVR MAV_3239|M.avium_104 ---- MMAR_3097|M.marinum_M ---- Mflv_2696|M.gilvum_PYR-GCK ---- Rv0101|M.tuberculosis_H37Rv ---- Mb0104|M.bovis_AF2122/97 ---- MLBr_01996|M.leprae_Br4923 ---- MUL_4858|M.ulcerans_Agy99 ---- Mvan_2578|M.vanbaalenii_PYR-1 ----