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M. gilvum PYR-GCK Mflv_2696 (-)

annotation: amino acid adenylation domain-containing protein
coordinates: 2831478 - 2836766
length: 1762

VTDTDLDARRLELLRRRLAGSGLREQDPAEPVAVAADPARGEFTDGQKRMWFVHSVDPSGVLLNVCLSYR
ISGEVDLARLHDAVTAVARRHPVLRTTFAADEAGEPQRTVHDDLLPGWTVQDISELSEHARRLRLEVLAQ
REFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWRVFFADLTRAYTGAELGPTPAPVVEPP
TSDEDLRFWRSAMTDLPEPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAAREAGATPYMVMLAAF
GALLHRYTHADDVLIASPVLLRGPDSEDVIGYHGNSAVMRLRPQPMQTFTELLSRTRDFALDAFAHQQVN
LDRVVRELNLDRRHGAERMTRVSFGFREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHESGAVVEA
EFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELMDGDDAEWLRRVSHGPEFDVPAATIGELIEA
RTDLTPDTVAVVYEGRRYTYREINESANRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGAVYL
PVDPSYPQDRMSFVLSDSDPTLVIREPVAGLDGHRTDNPTDDVRVRPLRPENAAYLIYTSGSTGQPKGVP
VPHRPVAEYFVWFKDEYEISESDRLLQVASPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAYLTELLQR
EGITAMHFVPSLLGLFLSLPGVNQWRTLERVPIGGEALPGELADRFHATFDALLHNFYGPTETIINTTRY
KVEGTQGSRIVPIGTPKINTTVHLLDDALRPVPVGAIGEIYIGGGHVARGYHRRPALTAERFVADPFTVG
GRLYRSGDLARRNADGDLEFVGRADDQVKIRGFRIELGEVAAAISVDPSVGQAVVLGQDLPGLGMSLVGY
VTPAAGEDVDLARVRERVAAALPDYMTPAGYVVLDEIPITAHGKIDRAALPLPEITTATDYREPQTETEQ
HLAQLFSELLGVARVGVDDSFFELGGHSLLATKLVSAVRSRCGVDMEIREIFELGTVARLAERVDELAAG
GSAPLRPRLLAVPHDGPAPMSAAQLRQWFQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHES
LRTTFCEIDGVPYQLVNAPDPGFPVRRDSGPDDAWLVGALDDERRRVFDLENQWPIRVAVLSIPGEHALS
VVVHHIAADHWSGGVLFTELLTAYRARRAGEAPTWAPLPVQYADYAAWQSALLADDSGIVAAQRRYWTQQ
LEGLSAETGLQPDLVRPSVPSGAADAVEFTLDAAIREKLVTLSREVGATEFMLLQAAVAVTLYKAGEGPD
IPLGTPVAGRTESELDQLIGFFINILVLRNDLRDNPSLRDVGFRSREMALAAYAHQDLPFDQVVDAVSPV
RSLSRNPLFGVVVHVREELPQDRVIATGSDGETTFTALEPTFDMAHADLSVNFFAGGNGYRGHVIYRTEL
YTRATAERFAGWLSAVITAFADDPERHVDDVVIAEPVRPGDGAEAVLLDGAGHPVPVGVVADVHYAGAPD
RRGDRARWTEDGRLQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYVVPAEPVDDPASFAETV
RAAVAPESAPTSITVLDALPATRRALPAPRVGGPSEPARTDTEKALVGMLADVLVEVHDGTGIGRFDDFF
ELGGDSILAVQLAARAKQAGLRLSARMVFEHPVVHDLAVALDTAKTPEVADVRHDPMSASGLTPEELAMV
ATSWAAEQDGSP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2696--100% (1762)amino acid adenylation domain-containing protein
M. gilvum PYR-GCKMflv_2697-2e-9727.90% (1283) amino acid adenylation domain-containing protein
M. gilvum PYR-GCKMflv_2692-2e-8027.80% (1043) amino acid adenylation domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2401cmbtE0.062.81% (1729) peptide synthetase MBTE (peptide synthase)
M. tuberculosis H37RvRv2380cmbtE0.062.81% (1729) peptide synthetase MBTE (peptide synthase)
M. leprae Br4923MLBr_01996nrp6e-2527.19% (445) putative peptide synthase
M. abscessus ATCC 19977MAB_2122-0.042.91% (1566) putative peptide synthetase MbtE
M. marinum MMMAR_3691mbtE0.043.49% (1529) non-ribosomal peptide synthetase MbtE
M. avium 104MAV_2013-0.065.34% (1529) linear gramicidin synthetase subunit D
M. smegmatis MC2 155MSMEG_4511-0.064.83% (1814) linear gramicidin synthetase subunit B
M. thermoresistible (build 8)TH_3141-0.062.16% (1826) PUTATIVE amino acid adenylation domain
M. ulcerans Agy99MUL_3634mbtE0.043.43% (1529) non-ribosomal peptide synthetase MbtE
M. vanbaalenii PYR-1Mvan_3845-0.061.47% (1801) amino acid adenylation domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      VTDTTETRPAGADDEARLALLRRRLSERGLSAQ---QTTGAAS---EDRL
Mvan_3845|M.vanbaalenii_PYR-1       ---MTDIDTGALLDERRLELLRRRMQERGLSAG---TDTAEPAG-DTDVL
MSMEG_4511|M.smegmatis_MC2_155      MTDIADTATAS-TVEARLELMRRKLAERGLAAGRAAAEGSAAAV-DPTVL
Mflv_2696|M.gilvum_PYR-GCK          -------MTDTDLDARRLELLRRRLAGSGLREQDPAEPVAVAADPARGEF
MAV_2013|M.avium_104                --MTETTGAGTRLDDERLELLRRKLAERGLSRS------AGTARHDEPRM
MMAR_3691|M.marinum_M               -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPGICPG-ERYRL
MUL_3634|M.ulcerans_Agy99           -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPRICPG-ERYRL
MAB_2122|M.abscessus_ATCC_1997      -----MTGDQLSALDRRRELLRRRLAESGVAAQAVESAPRVQAG-ERRGL
MLBr_01996|M.leprae_Br4923          ------------------------------------MTAPNTRRVDRVPL
                                                                                      

Mb2401c|M.bovis_AF2122/97           ------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRI
Rv2380c|M.tuberculosis_H37Rv        ------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRI
TH_3141|M.thermoresistible__bu      SDGQLRMWFVHQADPSGALLNICLSYRISGPVDLAALRGALDAVARRHPV
Mvan_3845|M.vanbaalenii_PYR-1       TEGQLRMWFVHNADPSGALLNVCLSYRLSGEIDVARLHDAVGAVARRHRV
MSMEG_4511|M.smegmatis_MC2_155      SDGQRRMWFVQGFDPSGVLLNVSLSYRLTGDIDAERMQAAVEAVARRHPI
Mflv_2696|M.gilvum_PYR-GCK          TDGQKRMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVARRHPV
MAV_2013|M.avium_104                SVGQHRMWFVQSVDPDSALLNICVSYRLTGGVDTGRLHRAVDAVAARHPV
MMAR_3691|M.marinum_M               SDGQRRMWFLQTMDPDDVTLNICVAYRLAGLVDEDRLHTAVNDVVARHAI
MUL_3634|M.ulcerans_Agy99           SDGQRRMWFLQTMDPDDVTLNICVAYRLTGLVDEDRLHTAVNDVVARHAI
MAB_2122|M.abscessus_ATCC_1997      APGQRRMWFMQTKDPADTSLNICVAHRMRGALDQTRLRDAVAAVIRRHDV
MLBr_01996|M.leprae_Br4923          SRSQQNIYNGMLQDNDPALYFIGKSYRFH-QLELSVFLAALEATILKNPG
                                          ::     *   .   :  ::*:   ::   :  *:  .  ::  

Mb2401c|M.bovis_AF2122/97           LRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLRL
Rv2380c|M.tuberculosis_H37Rv        LRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLRL
TH_3141|M.thermoresistible__bu      LRTTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQARRLRL
Mvan_3845|M.vanbaalenii_PYR-1       LRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ERARGLRL
MSMEG_4511|M.smegmatis_MC2_155      LRTTF-----HADENGEPRAEVHDDLTPSWTTHDLSEKS---ERARKLRL
Mflv_2696|M.gilvum_PYR-GCK          LRTTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EHARRLRL
MAV_2013|M.avium_104                LHTTY-----DTTDEGDPRPVLRADLRPEWAEHDLSGLT---EQARRLRL
MMAR_3691|M.marinum_M               LRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHERQI
MUL_3634|M.ulcerans_Agy99           LRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHEQQI
MAB_2122|M.abscessus_ATCC_1997      LRTVY-----GVDSAGEPYQLFVEEFEVPWTAVDLTDLT---GDAQDRQV
MLBr_01996|M.leprae_Br4923          QLCVL---------EAPSTEGDYPDLVPRLQFGDIVRVR--SDEQPQTDS
                                       .           . .       .       *:               

Mb2401c|M.bovis_AF2122/97           EVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRV
Rv2380c|M.tuberculosis_H37Rv        EVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRV
TH_3141|M.thermoresistible__bu      EVLAQREFTAPFDLSVDSPLRITMIRTGADEHIMLLVAHHIAWDDGSWEV
Mvan_3845|M.vanbaalenii_PYR-1       EVLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWDDASWEV
MSMEG_4511|M.smegmatis_MC2_155      EVLAQREFGTPFDLGTESPLRLTLIRTGPAEHVLLLVAHHIAWDDGSWRV
Mflv_2696|M.gilvum_PYR-GCK          EVLAQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWRV
MAV_2013|M.avium_104                DVLAQRDFRRPFDLSKDSPLRVTAARLADDELMLLITAHHIAWDDGSWAP
MMAR_3691|M.marinum_M               ESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWEV
MUL_3634|M.ulcerans_Agy99           ESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWEV
MAB_2122|M.abscessus_ATCC_1997      RALADSEFGRPFDLAADRPLRVTLLRLGAEDFVVLLVVHHICWDDNSWEV
MLBr_01996|M.leprae_Br4923          RDYDLMHAWSPDILAKPLVRYTVRTDKNGFVARLDVFTHHILVDGGAIRI
                                          .   *  *        .          : : .***  *. .   

Mb2401c|M.bovis_AF2122/97           FFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPPE
Rv2380c|M.tuberculosis_H37Rv        FFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPPE
TH_3141|M.thermoresistible__bu      FFDDLTRAYT-----GVDLGEELAPQLPPGPRDPDADLAYWREVLADPPE
Mvan_3845|M.vanbaalenii_PYR-1       FFDDLTGAYV-----GEKLRPARRPVVAAGGSD-EDDVAYWRAVMADPPE
MSMEG_4511|M.smegmatis_MC2_155      FFTDLTRAYS-----GEQLPETPR-VGAAAPDTTDEDLAYWREVMANPPE
Mflv_2696|M.gilvum_PYR-GCK          FFADLTRAYT-----GAELGPTPAPVVEP--PTSDEDLRFWRSAMTDLPE
MAV_2013|M.avium_104                FFADLTRAYTAPG--DFDATPVVPDLSADPTAIRREDLDYWRPLMADLPE
MMAR_3691|M.marinum_M               FFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLPE
MUL_3634|M.ulcerans_Agy99           FFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLPE
MAB_2122|M.abscessus_ATCC_1997      FFAELSEYYHGRPVQGEAPQFMVVS--ADTEPSSDADLTYWRRALTPLPD
MLBr_01996|M.leprae_Br4923          IEENLAHHLDTDN---RLEIPCIRQALDKLAEAHRREATKVEESLQRLAN
                                    :  :*:                              :       :   .:

Mb2401c|M.bovis_AF2122/97           PLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLA
Rv2380c|M.tuberculosis_H37Rv        PLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLA
TH_3141|M.thermoresistible__bu      PLELPGPHGSAVPSGWRSARDSVTLGADTARRVVELAQETGCTPYAVLLA
Mvan_3845|M.vanbaalenii_PYR-1       PLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALADEVGATPYAVLLA
MSMEG_4511|M.smegmatis_MC2_155      PLELPGPMGSVVPTGFRSQRSTVRLSAETVEKVTVLARETGATPYMVLLA
Mflv_2696|M.gilvum_PYR-GCK          PLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAAREAGATPYMVMLA
MAV_2013|M.avium_104                PLELPGPNGSVVPSTWRAQRAFAELPAEIVDRAAALARETGATPYMVLMA
MMAR_3691|M.marinum_M               PPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEDFARKCSASPFMVLLA
MUL_3634|M.ulcerans_Agy99           PPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEEFARKCSASPFMVLLA
MAB_2122|M.abscessus_ATCC_1997      PLELPGAAS--TYSSRAARRLAVPMPAETAARIEEFAREHSATPFMVLLA
MLBr_01996|M.leprae_Br4923          VVQRELADEVRNGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALSE
                                      :                .      .    :        .     .:  

Mb2401c|M.bovis_AF2122/97           AFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMS
Rv2380c|M.tuberculosis_H37Rv        AFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMS
TH_3141|M.thermoresistible__bu      VFGTLIFRYTHADDFLVATPVLNRDSGAEQRIGYYGNTVAMRLRPNAAMS
Mvan_3845|M.vanbaalenii_PYR-1       VFGVLIHRYSHVDDFLVATPVLNRNGDTDDVIGYFGNTVAMRLRPHPAMT
MSMEG_4511|M.smegmatis_MC2_155      AFGALIRRYTHTDDFLVATPVLNR--DTEDTIGYHGNTVAMRMRPRSDAG
Mflv_2696|M.gilvum_PYR-GCK          AFGALLHRYTHADDVLIASPVLLRGPDSEDVIGYHGNSAVMRLRPQPMQT
MAV_2013|M.avium_104                AFAALVHRYTGSTDFLVAAPVLNRGAATENVIGYYGNTVVIRLRPQSHQS
MMAR_3691|M.marinum_M               AYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQDT
MUL_3634|M.ulcerans_Agy99           AYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQDT
MAB_2122|M.abscessus_ATCC_1997      AFGVLVHRYTGSRDFVTAIPVAERKSNAEKAIGYFGNTLLLRTVVNPDDS
MLBr_01996|M.leprae_Br4923          TKQVPLN--ILVATAAVAVDASLRQSTEGLLVHAVDNRFGDPYLDVATCL
                                    .  . :           :  .  *       :   .*         .   

Mb2401c|M.bovis_AF2122/97           FRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSFG
Rv2380c|M.tuberculosis_H37Rv        FRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSFG
TH_3141|M.thermoresistible__bu      FRDMLAQSRDTALGAFAHQGINLDRVVRELNPDR---RHGTERMTRVSFG
Mvan_3845|M.vanbaalenii_PYR-1       FRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDR---RHGAERMTRVSFG
MSMEG_4511|M.smegmatis_MC2_155      FRDLVLQTRDVALGAFAHQRVNLDRVVRELNPDR---RHGAERMTRVSFG
Mflv_2696|M.gilvum_PYR-GCK          FTELLSRTRDFALDAFAHQQVNLDRVVRELNLDR---RHGAERMTRVSFG
MAV_2013|M.avium_104                FRELLAQTRDGAVGAFAHSRADLDWLVRESNPDR---RHGADRMTRVSFG
MMAR_3691|M.marinum_M               FTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGFN
MUL_3634|M.ulcerans_Agy99           FTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGFN
MAB_2122|M.abscessus_ATCC_1997      FASHVAAVREVCLDAFGHQNVGIDEVVREVNPSRSIGHDGMDELVRLGFS
MLBr_01996|M.leprae_Br4923          VNSVAHSIRFPPFASVQDVVRTLDRSYVKAIRLR---WLREEYYRRIYLA
                                    . .     *     .. .    :*    :    *       :   *: : 

Mb2401c|M.bovis_AF2122/97           FREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRAG-----VLVEA
Rv2380c|M.tuberculosis_H37Rv        FREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRAG-----VLVEA
TH_3141|M.thermoresistible__bu      FRGPDRFGFTPPGVRCERAELRSHLTQLPLGVMIEFDPDPADP-GATVEI
Mvan_3845|M.vanbaalenii_PYR-1       FRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDPD-----EVVVEL
MSMEG_4511|M.smegmatis_MC2_155      FREPDGGGFCPAGVRCERAELRGNHTQLPLGFMVEWEATG-----ATVEA
Mflv_2696|M.gilvum_PYR-GCK          FREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHESG-----AVVEA
MAV_2013|M.avium_104                QREPDGAGFCPPGVRCERGDLRGHFNQLPLSLMVELNRTPDGSGGGLVEA
MMAR_3691|M.marinum_M               MR-KSAGGLALDGVVVRQLGLGAVAAHLPLSLTIALDPDD-----VSVEF
MUL_3634|M.ulcerans_Agy99           MR-KSAGGLALDGVVVRQLGLGAIAAHLPLSLTIALDPDD-----VSVEF
MAB_2122|M.abscessus_ATCC_1997      MR-KDASGYRLEGVDVTQLDLAAVSAQLPLSLAIATESSG-----TIVEF
MLBr_01996|M.leprae_Br4923          LNQTSHIEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEG------MTV
                                     .  .       ..               :                 :  

Mb2401c|M.bovis_AF2122/97           EHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLRE
Rv2380c|M.tuberculosis_H37Rv        EHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLRE
TH_3141|M.thermoresistible__bu      EHLVEVIEPALGRQLLRHFVVLLEDALRRPDTPLSRLRLMDDADLAWLRD
Mvan_3845|M.vanbaalenii_PYR-1       EHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSGLQLMGDDDLEWLRA
MSMEG_4511|M.smegmatis_MC2_155      EHLTEVLDAALAEQMLRHFTVLLDNALADPDRALWRLDLFTAEDTAWLTR
Mflv_2696|M.gilvum_PYR-GCK          EFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELMDGDDAEWLRR
MAV_2013|M.avium_104                EYLVEVLDQQLVEQMLRHYRTLLDSLLSDPDATLSACALMSDADAEWLRA
MMAR_3691|M.marinum_M               EYQQQLS-SVLVDQMLVHYLQLVDKALAEPERPLSSLDILGAGERDSVLA
MUL_3634|M.ulcerans_Agy99           EYQQQLS-SVLVDQMLAHYLQLVDKALAEPERPLSSLDILGAGERDSVLA
MAB_2122|M.abscessus_ATCC_1997      EYQTDVLPQWLVGQLLVHYQRLLADGLSRPEETLARLELFDAEEHSALLD
MLBr_01996|M.leprae_Br4923          ACVLNEDERTLDLSIWNRVDLPQGKSCTRVAKRIAAALELMAAAWDQPIA
                                        :     *  .:  :               :     :          

Mb2401c|M.bovis_AF2122/97           VSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEA--
Rv2380c|M.tuberculosis_H37Rv        VSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEA--
TH_3141|M.thermoresistible__bu      VSRGDRFDTPARTLPDLIESQVRQT--PDAVAVVYEGRHYSYRELNEA--
Mvan_3845|M.vanbaalenii_PYR-1       VSVGPTFDTPPATITDLIEAQVRRS--PDGTAVVYEGRHYTYREINEA--
MSMEG_4511|M.smegmatis_MC2_155      MATGEAFDTPAATLTDLVTQQAERT--PDATAVVYEGRHFTYREINES--
Mflv_2696|M.gilvum_PYR-GCK          VSHGPEFDVPAATIGELIEARTDLT--PDTVAVVYEGRRYTYREINES--
MAV_2013|M.avium_104                VSTGEQFITPAATLSELVSRRAART--PDAVAVVYEGRTYTYRDIEEE--
MMAR_3691|M.marinum_M               QSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRR--
MUL_3634|M.ulcerans_Agy99           QSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRR--
MAB_2122|M.abscessus_ATCC_1997      QSHGVLTRPSAATLVDLLDAAARAT--PEALAVVSDDVELTYELLQQR--
MLBr_01996|M.leprae_Br4923          MIVNEWFGISSDGALCLGNEVTQTTR-PLAPAWFLDPGGSVHLTVDKRRY
                                       .     .      *    .  :  .   * . :     :  :..   

Mb2401c|M.bovis_AF2122/97           SNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSY
Rv2380c|M.tuberculosis_H37Rv        SNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSY
TH_3141|M.thermoresistible__bu      ANRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVLKAGAVYLPIDPTY
Mvan_3845|M.vanbaalenii_PYR-1       ANRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKAGAVYVPIDPAY
MSMEG_4511|M.smegmatis_MC2_155      ANRLAHWLIGQGIGTEDRVAVLLEKSPELVITALGIVKAGAVYLPVDPTY
Mflv_2696|M.gilvum_PYR-GCK          ANRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGAVYLPVDPSY
MAV_2013|M.avium_104                SNRVAHWLIERGVGTEDRVAVLLDKSPELVITALGVLKAGGVYLPVDPTY
MMAR_3691|M.marinum_M               ANRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAY
MUL_3634|M.ulcerans_Agy99           ANRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAY
MAB_2122|M.abscessus_ATCC_1997      SNRFARWLVAQGAGTEDVIALQMSTSVEFIVAMLGVLKSGAAYMPIDPAL
MLBr_01996|M.leprae_Br4923          VHPWIAWLVRGSVVPGDVLVFTDDNTDKTIDLLIACHLAGCGYSVCDTVA
                                     :    *::  .  . * : .    : . :   :.   :*  *   *.  

Mb2401c|M.bovis_AF2122/97           PQDRLDFILADCDAKLVLRTPVRELAGYRSD-----DPTDADRIRPLRP-
Rv2380c|M.tuberculosis_H37Rv        PQDRLDFILADCDAKLVLRTPVRELAGYRSD-----DPTDADRIRPLRP-
TH_3141|M.thermoresistible__bu      PDDRLSFILGDCDARLVLREPVSDLDGQPTT-----DPTDTDRVRRLLP-
Mvan_3845|M.vanbaalenii_PYR-1       PQDRLEFILGDCDAKVVVREPVTGLDGYRAD-----DPGDNDRRRPVGP-
MSMEG_4511|M.smegmatis_MC2_155      PEDRLNYILSDSDPKIVLREFVTGLDDQPTT-----DPTDAERVRPLRP-
Mflv_2696|M.gilvum_PYR-GCK          PQDRMSFVLSDSDPTLVIREPVAGLDGHRTD-----NPTDDVRVRPLRP-
MAV_2013|M.avium_104                PQDRLNFILGDADAKLVLREPVTDLADYPAT-----APT--ELLRPLTP-
MMAR_3691|M.marinum_M               PDERIDYLITDARPQTVIGRPELDVAERAAADNSDLPLSDSDRLRPLRP-
MUL_3634|M.ulcerans_Agy99           PDERIDYLITDARPQTVIGRPELDVAERAAADNSDLPLSDGDRLRPLRP-
MAB_2122|M.abscessus_ATCC_1997      PEERIEYLIADAKPRIVMRPQEFRVAEAAATGLGDAPITDADRLRPLLP-
MLBr_01996|M.leprae_Br4923          EVPLRAKAITDHGGGVSARVIDVAATQLAVTPDNEQSKLADKLIKQAAQD
                                            : *                                 :     

Mb2401c|M.bovis_AF2122/97           ----DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLL
Rv2380c|M.tuberculosis_H37Rv        ----DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLL
TH_3141|M.thermoresistible__bu      ----GNTAYLIYTSGTTGLPKGVPVPHRPVAEYFVWFKGDYQVDANDRLL
Mvan_3845|M.vanbaalenii_PYR-1       ----YNTAYLIYTSGSTGLPKGVPVPHRPVAEYFVWFKGDYRVDAGDRML
MSMEG_4511|M.smegmatis_MC2_155      ----DNTAYLIYTSGSTGLPKGVPVPHRPIAEYFVWFGGEYDVTNEDRLL
Mflv_2696|M.gilvum_PYR-GCK          ----ENAAYLIYTSGSTGQPKGVPVPHRPVAEYFVWFKDEYEISESDRLL
MAV_2013|M.avium_104                ----QNTAYLIYTSGSTGLPKGVPVPHAPIAEYFVWFGDEYRIDETDRLL
MMAR_3691|M.marinum_M               ----GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWTMTAEDRWL
MUL_3634|M.ulcerans_Agy99           ----GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWTMTAEDRWL
MAB_2122|M.abscessus_ATCC_1997      ----DNLAYVIYTSGSTGRPKGVAVAHAAIAEHVVSFTAEWSMTADDRML
MLBr_01996|M.leprae_Br4923          ISLADKTAYIMPTSGSTGQPKLVQVSHGSLALFCDAVRNAYGWGAHDTIL
                                         : **:: ***:** ** * *.* .:* .   .   :     *  *

Mb2401c|M.bovis_AF2122/97           QVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAM
Rv2380c|M.tuberculosis_H37Rv        QVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAM
TH_3141|M.thermoresistible__bu      QVASPSFDVSIAEIFGTLACGARLVIHRPGGLNDIGYLTALLQDEGITAM
Mvan_3845|M.vanbaalenii_PYR-1       QVASPSFDISIAEVFGTLACGARLVIHRPGGLNDIGYLTALLRDEGITAM
MSMEG_4511|M.smegmatis_MC2_155      QVASQSFDVSIGEIFGMLAAGARLVIPKPGGLTDIGYLTDLLRNEGITSM
Mflv_2696|M.gilvum_PYR-GCK          QVASPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAYLTELLQREGITAM
MAV_2013|M.avium_104                QVASPSFDVSIGEIFGTLIMGARLVIPRPDGLRDIGYLTELLAREGITSM
MMAR_3691|M.marinum_M               QFSSVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVTVL
MUL_3634|M.ulcerans_Agy99           QFSSVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVTVL
MAB_2122|M.abscessus_ATCC_1997      QSTSVSFDASLADILCPLSLGAQLVIPKPNPFSDIGYVADLVRRRGVTVL
MLBr_01996|M.leprae_Br4923          QCAPLTSDISVEEIFGGAICGSKLVRSTAMKTGDLAELARDIFVQRATVI
                                    * :. : * *: :::     *.:::   .    *:. ::  :  .  * :

Mb2401c|M.bovis_AF2122/97           HFVPSLLGLFLSLPGVSQWR---TLQRVPIGGEPLPGEVADKFHAT---F
Rv2380c|M.tuberculosis_H37Rv        HFVPSLLGLFLSLPGVSQWR---TLQRVPIGGEPLPGEVADKFHAT---F
TH_3141|M.thermoresistible__bu      HFVPSLLGLFLSLPGVNQWR---TLQRVPIGGEPLPGEVADKFHAT---F
Mvan_3845|M.vanbaalenii_PYR-1       HFVPSLLGLFLSLPGVNQWR---TLQRVPIGGEALPGEVADKFRAT---F
MSMEG_4511|M.smegmatis_MC2_155      HFVPSLLGLFLSLPGVNEWR---TLQRVPIGGEALPGEIADKFHAT---F
Mflv_2696|M.gilvum_PYR-GCK          HFVPSLLGLFLSLPGVNQWR---TLERVPIGGEALPGELADRFHAT---F
MAV_2013|M.avium_104                HFVPSLLGLFLSLPGVSQWR---TLRRVPIGGEALPGEIADKFHAT---F
MMAR_3691|M.marinum_M               HLVPSMLSTLLLLPQVQQWR---QLRHVPVGGEALPGEVADRFAGY---F
MUL_3634|M.ulcerans_Agy99           HLVPSMLSTLLLLPQVQQWR---QLRHVPVGGEALPGEVADRFAGY---F
MAB_2122|M.abscessus_ATCC_1997      HMVPSLLGSVLLLPEARELR---GLRHVPVGGEALPGEVADKFATM---F
MLBr_01996|M.leprae_Br4923          DLPTAVWHLLCDHSDAIDEINRSCLRQIVIGGEAVRPCAVDKWIDSGASQ
                                    .: .::   .   . . :      *.:: :***.:    .*::       

Mb2401c|M.bovis_AF2122/97           DALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQ
Rv2380c|M.tuberculosis_H37Rv        DALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQ
TH_3141|M.thermoresistible__bu      DALLHNFYGPTETVINASRYKVEGKQGTRIVPIGRPKINTQLHLLDNALQ
Mvan_3845|M.vanbaalenii_PYR-1       DALLHNFYGPTETVINATRFKVEGRQGTRIVPIGKPKINTAIHILDDALQ
MSMEG_4511|M.smegmatis_MC2_155      DSLLHNFYGPTETVLNCTRYKVEGKQGARTVPIGKPKINTTIHLLDDALQ
Mflv_2696|M.gilvum_PYR-GCK          DALLHNFYGPTETIINTTRYKVEGTQGSRIVPIGTPKINTTVHLLDDALR
MAV_2013|M.avium_104                DASLYNFYGPTETVVNCTSYPVEGAQGTRVVPIGRPKINTRVYLLDNALQ
MMAR_3691|M.marinum_M               DAELRNHYGPTEAVVCSTHMVVTGSHGARVVPIGVPNRNVYAYVLDEQLH
MUL_3634|M.ulcerans_Agy99           DAELRNHYGPTEAVVCSTHMLVTGSHGARVVPIGVPNRNVYAYVLDEQLH
MAB_2122|M.abscessus_ATCC_1997      DAELRNHYGPTEAVVCSTYMSVRGPQGNSIVPIGRPNQNVYAYVLDQALK
MLBr_01996|M.leprae_Br4923          GISLMSTYGPTETTVVVTYLPIVCAP-------MTVESDARLRLGWPIVP
                                    .  * . *****: :  :   :              : :.   :    : 

Mb2401c|M.bovis_AF2122/97           PVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLA
Rv2380c|M.tuberculosis_H37Rv        PVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLA
TH_3141|M.thermoresistible__bu      PVPVGVIGEIYIGGTHVAHGYHRRPGLTAERFVADPFNPGGRLYRSGDLA
Mvan_3845|M.vanbaalenii_PYR-1       PVPVGSIGEIYIGGTHVARGYHHRPGLTAERFVADPFTPGARMYRSGDLA
MSMEG_4511|M.smegmatis_MC2_155      PVPVGVIGEIYIGGTHVAHGYHRRPGMTAERFVADPFNPGGRMYRSGDLA
Mflv_2696|M.gilvum_PYR-GCK          PVPVGAIGEIYIGGGHVARGYHRRPALTAERFVADPFTVGGRLYRSGDLA
MAV_2013|M.avium_104                PVPPGVIGEIYIAGTHVAHGYHRRPQLTAERFVADPFSRGGRMYRSGDLA
MMAR_3691|M.marinum_M               PVPDQVIGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLV
MUL_3634|M.ulcerans_Agy99           PVPDQVVGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLV
MAB_2122|M.abscessus_ATCC_1997      LVPAGVVGELYLGGAQLARGYRARPVLTAERFVADPFGSGGRLYRTGDLV
MLBr_01996|M.leprae_Br4923          NTVFIAFGELVIVGDLVSVGYLGIDSRNFG-TVTTTDGSCRRAFATADCV
                                     .    .**: : *  :: **      .    :: .     * : :.* .

Mb2401c|M.bovis_AF2122/97           RRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDL
Rv2380c|M.tuberculosis_H37Rv        RRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDL
TH_3141|M.thermoresistible__bu      RRNADGDIEFVGRADEQVKIRGFRIELGDVAAAISVDPSVGQAVVVATDL
Mvan_3845|M.vanbaalenii_PYR-1       RRNADGDIEFVGRADEQVKIRGFRIELGDVAAAITVDPSVGQAVVVVSDL
MSMEG_4511|M.smegmatis_MC2_155      RRNADGDIEFVGRADEQVKIRGFRIELGEVSAAISVDPSVGQAVVVVSDL
Mflv_2696|M.gilvum_PYR-GCK          RRNADGDLEFVGRADDQVKIRGFRIELGEVAAAISVDPSVGQAVVLGQDL
MAV_2013|M.avium_104                RRNANGDIEFVGRADEQVKIRGFRIELGEIAAAISVDPSVGQAVVLAMDL
MMAR_3691|M.marinum_M               RRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEE
MUL_3634|M.ulcerans_Agy99           RRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEE
MAB_2122|M.abscessus_ATCC_1997      RRNARGELEFVGRADEQVKVRGYRIELGEIEAVIGADPRVGHCVATVVDD
MLBr_01996|M.leprae_Br4923          ILDDEGFPVFSGRKDAVVKISGKRVDTAELIRRISTDPNVSDVAVEVYNG
                                      :  *   * ** *  **: * *:: .::   * ..* * .  .   : 

Mb2401c|M.bovis_AF2122/97           PRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVV-
Rv2380c|M.tuberculosis_H37Rv        PRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVV-
TH_3141|M.thermoresistible__bu      PNVGRSLVGYLTPVSGE---STDSVAVERIRARVAAALPEYMVPAAYVV-
Mvan_3845|M.vanbaalenii_PYR-1       PNLGKSLVAYLTPADG------AGVDVDRIRTRVAAALPEYMTPAAYVV-
MSMEG_4511|M.smegmatis_MC2_155      PSLGKSLVAYITPAAG-----ADHVDIERIRARVTAALPEYMVPAAYVE-
Mflv_2696|M.gilvum_PYR-GCK          PGLGMSLVGYVTPAAG------EDVDLARVRERVAAALPDYMTPAGYVV-
MAV_2013|M.avium_104                PQLGKSLVGYVTPAQGAG---TETVDVERIRARVAAALPDYMTPAAYVV-
MMAR_3691|M.marinum_M               TEAGPMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAV-
MUL_3634|M.ulcerans_Agy99           TEAGPMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAV-
MAB_2122|M.abscessus_ATCC_1997      PQVGSLLAAYVVPAGG-----TREIDLDELRARAQEALPAYMVPTAFAV-
MLBr_01996|M.leprae_Br4923          -RLGVWFETKLTREG---------VDDAAAATRSRLILASLGVSSFFVVG
                                       *  :   :.            :       :    :.    .  :.  

Mb2401c|M.bovis_AF2122/97           LDEIPITAHGKIDR-AALPEPQIASDTEFRAPQTATERRLAQLFGELLG-
Rv2380c|M.tuberculosis_H37Rv        LDEIPITAHGKIDR-AALPEPQIASDTEFRAPQTATERRLAQLFGELLG-
TH_3141|M.thermoresistible__bu      LDEIPITTHGKIDR-AALPEPQIASMIEYREPATDTEREVARLFGDLLGR
Mvan_3845|M.vanbaalenii_PYR-1       VDEIPITAHGKIDR-AALPEPEIAPTTEFREPAAGTEAHLAQLFAELLG-
MSMEG_4511|M.smegmatis_MC2_155      LDEIPITTHGKIDR-RALPEPEITSTTRFREPSTDTERTVAGLFAELLE-
Mflv_2696|M.gilvum_PYR-GCK          LDEIPITAHGKIDR-AALPLPEITTATDYREPQTETEQHLAQLFSELLG-
MAV_2013|M.avium_104                LDEIPITAHQKIDR-AALPQPQIGAGTEYRDPTTPTEHRIAQLFSGLLG-
MMAR_3691|M.marinum_M               IPEIPMTVSGKLDR-RALPAPTPIATRRYREPETATERWICSIFAQLFG-
MUL_3634|M.ulcerans_Agy99           IPEIPMTVSGKLDR-RALPAPTPIATRRYREPETATERWICSIFAQLFG-
MAB_2122|M.abscessus_ATCC_1997      IPEIPLTTSGKLDK-RALPTPDALTERAFRLPVTPTERRMCAIYSHLFG-
MLBr_01996|M.leprae_Br4923          VPCIPRKPNGKIDRDNLLVMPQLVDSVQNYAGSGEGAAGLAEIWSRHLG-
                                    :  ** .   *:*:   *  *                  :. ::.  :  

Mb2401c|M.bovis_AF2122/97           RDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALA
Rv2380c|M.tuberculosis_H37Rv        RDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALA
TH_3141|M.thermoresistible__bu      SERIGADDSFFDLGGHSLLATKLVAAVRSAFGVDIGVQDVFELGTVARLA
Mvan_3845|M.vanbaalenii_PYR-1       HEKVGADDSFFDLGGHSLLATKLVAELRAGFGVDVEVRDIFENATIARLA
MSMEG_4511|M.smegmatis_MC2_155      RDEVGADDSFFDLGGHSLLATKLVAAVRARCAVDVGVQDVFEHATVSGLA
Mflv_2696|M.gilvum_PYR-GCK          VARVGVDDSFFELGGHSLLATKLVSAVRSRCGVDMEIREIFELGTVARLA
MAV_2013|M.avium_104                HERVGVDDSFFDLGGHSLVATKLVTAIRAECGVEIGIRDVFELATVGLLA
MMAR_3691|M.marinum_M               RQRVGAEDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDAPTPAGLA
MUL_3634|M.ulcerans_Agy99           RQRVGAEDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDVPTPAGLA
MAB_2122|M.abscessus_ATCC_1997      KERVGLDDSFFELGGHSLLAARLVAQIRAQFGIDLTVRAVFDRPTPAGLA
MLBr_01996|M.leprae_Br4923          -RAILPDSSLLDEGIGSVDLIRILPDTRRHLGRHLSLLDLISADNAANLT
                                       :  :.*::  *  *:   :::.  *   . .: :  ::.  .   *:

Mb2401c|M.bovis_AF2122/97           G------------HIDTLDSDS----------ARPRLTRVDHDGPVRLSS
Rv2380c|M.tuberculosis_H37Rv        G------------HIDTLDSDS----------ARPRLTRVDHDGPVRLSS
TH_3141|M.thermoresistible__bu      G------------RIDELRSGSG-------GPLRPRLTPQHFDGPAPLSS
Mvan_3845|M.vanbaalenii_PYR-1       A------------HLDTMGRATI-------GTRRPRLVAAPLDGPAPLSS
MSMEG_4511|M.smegmatis_MC2_155      A------------HIEDLVASGA-------SSGRPAIVAVPHDGPLQMSA
Mflv_2696|M.gilvum_PYR-GCK          E------------RVDELAAGGS-------APLRPRLLAVPHDGPAPMSA
MAV_2013|M.avium_104                E------------RVDQLSSGEL-------TGTRPKLIATAHDEPLPLSA
MMAR_3691|M.marinum_M               ARLVERFRNDFELDLDNLAADD---MPLDPKRARPGFVKSARPQRLPLSH
MUL_3634|M.ulcerans_Agy99           ARLVERFRNDFELDLDNLAADD---MPLDPKQARPGFVKSARPQWLPLSH
MAB_2122|M.abscessus_ATCC_1997      EQLVTYFREEFEIELDELDLDESDEMEAAPQDGRPDLVAAERPERLPLSS
MLBr_01996|M.leprae_Br4923          A-------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           SQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILR
Rv2380c|M.tuberculosis_H37Rv        SQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILR
TH_3141|M.thermoresistible__bu      SQLRSWFAYRVDGPSVVNNIPFAARLHGPVDVDALEAAIGDVIARHEILR
Mvan_3845|M.vanbaalenii_PYR-1       SQLRSWFGYRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDVVERHAILR
MSMEG_4511|M.smegmatis_MC2_155      AQLRQWFQFRIDGPNPVNNVPFAARLSGPCDVDALIAAVGDVVARHEILR
Mflv_2696|M.gilvum_PYR-GCK          AQLRQWFQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHESLR
MAV_2013|M.avium_104                SQLRSWFAYRMDGPSPVNNIPFAARLTGPWDIDALIAAVGDVVARHEILR
MMAR_3691|M.marinum_M               SQLAAWFQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALR
MUL_3634|M.ulcerans_Agy99           SQLAAWFQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALR
MAB_2122|M.abscessus_ATCC_1997      SQLSMWFECQMEGVTDIGNMWLALRFDGPLQTPALIAALNDVVARHEALR
MLBr_01996|M.leprae_Br4923          -----------------------------AQTANVWMDVGTAAEIERDLA
                                                                  :   .   :  .   .  * 

Mb2401c|M.bovis_AF2122/97           TVYREIGGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLET
Rv2380c|M.tuberculosis_H37Rv        TVYREIGGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLET
TH_3141|M.thermoresistible__bu      TVYREIDGVPYQIVLPTEP-VPVRRADGQGEQWLRAELDAERRHVFDLEN
Mvan_3845|M.vanbaalenii_PYR-1       TTYREIDGVPYQIVNPISD-VPVRRARGEGEQWLQAELDRERKHTFDLEE
MSMEG_4511|M.smegmatis_MC2_155      TTYREIDGAPYQIIHPPAP-VPVRQARGDGEDWVQAQLDAERRYCFDLET
Mflv_2696|M.gilvum_PYR-GCK          TTFCEIDGVPYQLVNAPDPGFPVRRDSGPDDAWLVGALDDERRRVFDLEN
MAV_2013|M.avium_104                TRYVELDGVPYQVVGPPGVEIPVRREDGPDDPWLQQQLDAERRHCFELDG
MMAR_3691|M.marinum_M               TNFDEHEGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPES
MUL_3634|M.ulcerans_Agy99           TNFDEHEGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPES
MAB_2122|M.abscessus_ATCC_1997      TNIAIHEGAPYQIVHPSRELAVPILRSSPEG--LSDTLAELRHHIFGLET
MLBr_01996|M.leprae_Br4923          SLCRQRNATEFSVKQTRNS-------------------------------
                                    :      .. ..:  .                                  

Mb2401c|M.bovis_AF2122/97           DWPIRAALLSTPEQT-----------------------VLSLVVHHIAGD
Rv2380c|M.tuberculosis_H37Rv        DWPIRAALLSTPEQT-----------------------VLSLVVHHIAGD
TH_3141|M.thermoresistible__bu      ERPIRPAILSLRPDAGSPD----SPAGD--------VHVLSLVMHHIAGD
Mvan_3845|M.vanbaalenii_PYR-1       DWPIRAAVFTVGAVSPASDGGAVSPASDGGAVDPASDHVLSVVIHHIAGD
MSMEG_4511|M.smegmatis_MC2_155      DWPIRAAVLTTAEHH-----------------------VLSLVVHHIAAD
Mflv_2696|M.gilvum_PYR-GCK          QWPIRVAVLSIPGEH-----------------------ALSVVVHHIAAD
MAV_2013|M.avium_104                ELPIRVAVLRVANAAEH---------------------VLSLVVHHIASD
MMAR_3691|M.marinum_M               GPLLQANLLVLGPDTH----------------------VLLLIVHHIVSD
MUL_3634|M.ulcerans_Agy99           GPLLQANLLVLGPDTH----------------------VLLLIVHHIVSD
MAB_2122|M.abscessus_ATCC_1997      ESLIRPAIIELSAQEH----------------------VLALVVHHIVVD
MLBr_01996|M.leprae_Br4923          --HQKQAIVVLGASG-----------------------ILGTGFAQAVLD
                                        :  :.                              *   . : . *

Mb2401c|M.bovis_AF2122/97           HWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG-
Rv2380c|M.tuberculosis_H37Rv        HWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG-
TH_3141|M.thermoresistible__bu      HWSATVLFTDLLTAYRARTAGQEPAWAPLPVQYADFGAWESELLAEETG-
Mvan_3845|M.vanbaalenii_PYR-1       HWSGGVLFTDLVAAYRARKAGERPTWAPLPVQYTDYGAWQAELLSDDTG-
MSMEG_4511|M.smegmatis_MC2_155      HWSGTVLFTDLLTAYHARHAGSAVELPPLPVQYADFAAWQAELLAGTDD-
Mflv_2696|M.gilvum_PYR-GCK          HWSGGVLFTELLTAYRARRAGEAPTWAPLPVQYADYAAWQSALLADDSG-
MAV_2013|M.avium_104                HWSAGVLFADVMTAYRARRGGEAPSWAPLRVQYADYAAWQRTFLGDAGGQ
MMAR_3691|M.marinum_M               HASLEIVFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN---
MUL_3634|M.ulcerans_Agy99           HASLEIVFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN---
MAB_2122|M.abscessus_ATCC_1997      HASFTVIVDDLIAAYRARLEGQAPQWDPQPVQYADYVLWQRDAFAPDSE-
MLBr_01996|M.leprae_Br4923          LRQSGVLCPEVVLATRARLPEGDP---WTALQGVDGVRIERISFENGPGE
                                      .  ::  ::: * :**            :* .*    :   :      

Mb2401c|M.bovis_AF2122/97           ---IVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAI
Rv2380c|M.tuberculosis_H37Rv        ---IVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAI
TH_3141|M.thermoresistible__bu      ---IAGPQREYWTRQLAGLPEETGLRPDFPRPPVPSGLAEAVEFTIDAAV
Mvan_3845|M.vanbaalenii_PYR-1       ---IAGPQREYWIRQLADAPVESGLPLEFSRPRLPSGKGDAVEFTIDGQV
MSMEG_4511|M.smegmatis_MC2_155      ---TIDEQRRYWTTQLAGLPEENGLYPDFPRPPVPTGDGAALDFSIDADT
Mflv_2696|M.gilvum_PYR-GCK          ---IVAAQRRYWTQQLEGLSAETGLQPDLVRPSVPSGAADAVEFTLDAAI
MAV_2013|M.avium_104                ESAVAGAQREYWTRQLAGLPEDTGLRPDFPRQPVPSGDGESVDFHIDAAT
MMAR_3691|M.marinum_M               ---WGQTELDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAAR
MUL_3634|M.ulcerans_Agy99           ---WGQTELDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAAR
MAB_2122|M.abscessus_ATCC_1997      ---FGQAEVNFWRQQLAGVPTEIAVAHDRARPQILGKRGEVAKFVMEPER
MLBr_01996|M.leprae_Br4923          ---LEALIRDTDAGTLVNGVGNTNMLVPYRELRLANVELVSAIVDICASY
                                                   * .   :  :     .  :         . :    

Mb2401c|M.bovis_AF2122/97           RDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANL
Rv2380c|M.tuberculosis_H37Rv        RDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANL
TH_3141|M.thermoresistible__bu      REKLAGLCRDLGITEFMALQAAVAVVLHKAGSGSDIPLGTPVAGRSEPEL
Mvan_3845|M.vanbaalenii_PYR-1       RRQITELCRELGITEFMLLQAAVAVTLAKVGGGLDIPLGTPVAGRSEAEL
MSMEG_4511|M.smegmatis_MC2_155      RARLIALTRELGVTEFMLLQAAVAIALHKSGQGTDIPLGTPVAGRTAPEL
Mflv_2696|M.gilvum_PYR-GCK          REKLVTLSREVGATEFMLLQAAVAVTLYKAGEGPDIPLGTPVAGRTESEL
MAV_2013|M.avium_104                RAKLADVCRELGITEFMLLQTAVAVVLHKAGGGVDIPLGTPVAGRTEAEL
MMAR_3691|M.marinum_M               RAALTQLAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPAT
MUL_3634|M.ulcerans_Agy99           RSALTQLAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPAT
MAB_2122|M.abscessus_ATCC_1997      RQALTRMAEQRGVTEFMVYQAALAVVLHRLGGGTDIVIGSPVAARVHPHV
MLBr_01996|M.leprae_Br4923          STRLVHLSS-------FVVNADVTVPQVTDPRETPYPYAASKSLAELVVA
                                       :  :         :  :: :::             .:. :       

Mb2401c|M.bovis_AF2122/97           DQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVE
Rv2380c|M.tuberculosis_H37Rv        DQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVE
TH_3141|M.thermoresistible__bu      DQLVGFFINILVLRNDLSGNPSLREVCRRAREMALAAYAHQDLPFDQVVD
Mvan_3845|M.vanbaalenii_PYR-1       EQLVGFFVNFVVLRNDLRGNPTLREVLIRAREMALSAYSNQDVPFEQVVE
MSMEG_4511|M.smegmatis_MC2_155      DALIGFFINIVVLRNDLSGNPSLREVLRRSREMALAAYQHQDLPFDRVVD
Mflv_2696|M.gilvum_PYR-GCK          DQLIGFFINILVLRNDLRDNPSLRDVGFRSREMALAAYAHQDLPFDQVVD
MAV_2013|M.avium_104                DQLIGFFVNILVLRNDLDGNPTLRELLKRARETALAAYAHQDLPFDRVVD
MMAR_3691|M.marinum_M               AQLVGLFANVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVE
MUL_3634|M.ulcerans_Agy99           AQLVGLFANVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVE
MAB_2122|M.abscessus_ATCC_1997      AKLVGLFANMVALRNDLSGDPSLRSVLERSRDATLNAHAHQELPIEKLVE
MLBr_01996|M.leprae_Br4923          GSPSALDFTIVRLPRVLGEDYQLRNSSDILLSIVDACIALRAYPSATVTE
                                        .:  ..: *   *  :  **.      . .  .   :  *   :.:

Mb2401c|M.bovis_AF2122/97           AVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPT
Rv2380c|M.tuberculosis_H37Rv        AVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPT
TH_3141|M.thermoresistible__bu      AVSPVRTLARNPLFSVVVHVREQLPENRVIDHGPDG----DTTVTVLEPP
Mvan_3845|M.vanbaalenii_PYR-1       AVNPPRTLARNPLFQVVVHVREQLPQRQMIDT--------DTEFTALEPT
MSMEG_4511|M.smegmatis_MC2_155      AVSPVRSLSRNPLFGVVVHVRDDLPADQVIDDGGNG----ETRFTALEPT
Mflv_2696|M.gilvum_PYR-GCK          AVSPVRSLSRNPLFGVVVHVREELPQDRVIATGSDG----ETTFTALEPT
MAV_2013|M.avium_104                SVSPVRSLSRNPLFQVVVHVRDHLSATRVIETAPVGGDGQDTVCTSLDPV
MMAR_3691|M.marinum_M               ALNPPRALSRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVN
MUL_3634|M.ulcerans_Agy99           ALNPPRALSRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVN
MAB_2122|M.abscessus_ATCC_1997      AVNPVRSLSWNPLFQTMVNFRGADWGTAARDVTVSG----ETTVVPLPME
MLBr_01996|M.leprae_Br4923          EVTTGRAAAKAILGVVSALARSGQLGSGISVVRGEA--------------
                                     :.. *: :   *       *                             

Mb2401c|M.bovis_AF2122/97           FDAAQADLSVNFFAC---------GDEYRGHVIYRTELYERATAQRFADW
Rv2380c|M.tuberculosis_H37Rv        FDAAQADLSVNFFAC---------GDEYRGHVIYRTELYERATAQRFADW
TH_3141|M.thermoresistible__bu      FDAAHADLSLNFFAAE-------DGGGYRGHVIYRPELYSRDTAQRFADW
Mvan_3845|M.vanbaalenii_PYR-1       FDIAQADLSLNFLA---------DGTGYRGYLIYRPELYARRTIERLGRW
MSMEG_4511|M.smegmatis_MC2_155      FDVAHADLSLNFFAQNGNGGRAGEPAGYKGTVIYRTELYEPATARRLIGW
Mflv_2696|M.gilvum_PYR-GCK          FDMAHADLSVNFFAG---------GNGYRGHVIYRTELYTRATAERFAGW
MAV_2013|M.avium_104                FDMAHADLSVNFFGTDG-----AGDIGYNCHLIFRTDLYRRTTIERLAGW
MMAR_3691|M.marinum_M               FEVALLFLAIGMSVTP--------SGELDVQVIANADLYEPATVALIADA
MUL_3634|M.ulcerans_Agy99           FEVALLFLAIGMSVTP--------SGELDVQVIANADLYEPATVALIADA
MAB_2122|M.abscessus_ATCC_1997      VDVSYLDLNFALNVTP--------SGGLDVSVVANADLYDHETTRMIAQA
MLBr_01996|M.leprae_Br4923          --VAYADFLSEFASD-------------------ELNMAEWKYRLDQSDW
                                       :   :   :                      . ::            

Mb2401c|M.bovis_AF2122/97           LVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAG-----------
Rv2380c|M.tuberculosis_H37Rv        LVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAG-----------
TH_3141|M.thermoresistible__bu      LGRVVTAFAERPDITLRELEIGAPGERRRILEEWG---------------
Mvan_3845|M.vanbaalenii_PYR-1       LPRVVAAFVDTPDRALGDVDIVSAEERQRVSQEWST--------------
MSMEG_4511|M.smegmatis_MC2_155      LHRIIDAFATDADTTLRDIAVIDADERTLLIEDWSRRAVPPA--------
Mflv_2696|M.gilvum_PYR-GCK          LSAVITAFADDPERHVDDVVIAEPVRPG----------------------
MAV_2013|M.avium_104                LVRAVTAFADDLDQTLRDVALIDAGEQQRILRQWSRGAQPPRDRPRTIPE
MMAR_3691|M.marinum_M               LDAALAAFATTPDLPLSAVQLLPS--------------------------
MUL_3634|M.ulcerans_Agy99           LDAALAAFATTPDLPLSAVQLLPR--------------------------
MAB_2122|M.abscessus_ATCC_1997      LDTAFDAFVNNQESRVSEIVLLPA--------------------------
MLBr_01996|M.leprae_Br4923          AKRNPRRWS-----------------------------------------
                                           :                                          

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                LLQASRSLGADRIAVRCGAEHIDYPALHRRSDNLAALLVDRGVGPGTLVG
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                LSTRRSIELVVALVAIMKAGAGYFPVDPGYPSARKQFMLDDVRPPVVVAT
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                VEAVDTMPGLPGVELLSLDDPQVRALVDRDDVDPRAGRLRPPHPDDPMYL
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                VFTSGSTGKPKGAVGTHRSMAARLDWQLRHYPPRTDDVRLAQASITFLEG
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                GMEMLAGLAAGATMILADDAEHRDPEALGELMHRHSVAQVTAVPSLVSAL
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                LDSRPDAVRSLSRLVCGGEPVSTSLLQRLVSVCDEADGGGPELLNNIGST
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           -----------------------TARVYLLDDALKPVPVGVVGDVYYGGG
Rv2380c|M.tuberculosis_H37Rv        -----------------------TARVYLLDDALKPVPVGVVGDVYYGGG
TH_3141|M.thermoresistible__bu      -----------------------GGTVYVLDETLQPVPVGVVGDVYTAGP
Mvan_3845|M.vanbaalenii_PYR-1       -----------------------GARVQVLDADLAPAPVGVFGDLYLSG-
MSMEG_4511|M.smegmatis_MC2_155      -----------------LPQTEGATNVYVLDEWLEPVAIGVIGDVYYAGG
Mflv_2696|M.gilvum_PYR-GCK          ----------------------DGAEAVLLDGAGHPVPVGVVADVHYAGA
MAV_2013|M.avium_104                ETSGAVSRGPLSPPNPLVGKPVPGAQAYLLDDGLRPVPVGVVGELYYAGD
MMAR_3691|M.marinum_M               -----------------------ADLAKLLAPPLPAGPAASP--------
MUL_3634|M.ulcerans_Agy99           -----------------------ADLAKLLAPPLPAGPAASQ--------
MAB_2122|M.abscessus_ATCC_1997      -----------------------DAMAQLMAPPAAAVEPVTT--------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           PAVGARLARPSETA-------------TRFVADPFAAQPGSRLYRNGERG
Rv2380c|M.tuberculosis_H37Rv        PAVGARLARPSETA-------------TRFVADPFAAQPGSRLYRNGERG
TH_3141|M.thermoresistible__bu      ALAAAHWTRAGVTA-------------TRLVADPVGNRPGARLYRTGDRA
Mvan_3845|M.vanbaalenii_PYR-1       -------------------------------------GPFAQRHRTGDRA
MSMEG_4511|M.smegmatis_MC2_155      AVDASAEAANGVAA-------------QRFVPNPFG---AGRLYRTGDRA
Mflv_2696|M.gilvum_PYR-GCK          PDRRGDRARWTEDGRLQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRT
MAV_2013|M.avium_104                QLARGYWKRPGLTA-------------ARFVANPFGAEPGSRLYRSGDLA
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           VWK--------ADGQLELLAEIERLPTAQAAP------------------
Rv2380c|M.tuberculosis_H37Rv        VWK--------ADGQLELLAEIERLPTAQAAP------------------
TH_3141|M.thermoresistible__bu      RWI--------ADGVLEFVDAQP-PTIPAVRPDS----------------
Mvan_3845|M.vanbaalenii_PYR-1       RWD--------DDGRLEIAARAPGATVVEVAPPA----------------
MSMEG_4511|M.smegmatis_MC2_155      RWT--------PDGRLEPVTAGEPRLQAALEAVDGVAAAATRYWEN----
Mflv_2696|M.gilvum_PYR-GCK          AVVGYVVPAEPVDDPASFAETVRAAVAPESAPTSITVLDALP--------
MAV_2013|M.avium_104                RWT--------EDGQLEFVGRSDHQVQVRGFRVELAEVEAALAGADGVAA
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      ---------------------RSAPLLAAYVVADAAHAADPQFAEQVRTA
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                AAARTWEVHGGTSLAGYVVPQRPIADEAEKAAFAAQVRAEIAATLPGYMM
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           -------------------------------VPAEPADTETERALAAILA
Rv2380c|M.tuberculosis_H37Rv        -------------------------------VPAEPADTETERALAAILA
TH_3141|M.thermoresistible__bu      -----------------------------GQRPGGPPATDTERALATLLA
Mvan_3845|M.vanbaalenii_PYR-1       -----------------------------VEFE--EPRTDSERALAALLS
MSMEG_4511|M.smegmatis_MC2_155      LPDEFAGAAITVVDDLTPAALTRPRVSATASGPFEAPATPTERAVAAMLV
Mflv_2696|M.gilvum_PYR-GCK          -------------------ATRRALPAPRVGGPSEPARTDTEKALVGMLA
MAV_2013|M.avium_104                PSSLTVLDALPKTESGKLNRPGLPRPAVSTGGRTEPARTDTERALANVFA
MMAR_3691|M.marinum_M               --------------------------------PVAAGSAETERRLTAMLE
MUL_3634|M.ulcerans_Agy99           --------------------------------PVAAGSAETERRLTAMLE
MAB_2122|M.abscessus_ATCC_1997      --------------------------------PSVEGSEETKLVLISILE
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2401c|M.bovis_AF2122/97           DVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVFEH
Rv2380c|M.tuberculosis_H37Rv        DVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVFEH
TH_3141|M.thermoresistible__bu      EVLDTEVTG----RDDDFFSLGGDSILAVQLAARARDTGLKLTARMVFEH
Mvan_3845|M.vanbaalenii_PYR-1       ELLATEEVG----RHDDFFGLGGDSVLAVQLAARARDTGLDLTARMVFEH
MSMEG_4511|M.smegmatis_MC2_155      ELLGVTQVG----RHDDFFTLGGDSILAVQLAARARDAGVAMTARMVFEH
Mflv_2696|M.gilvum_PYR-GCK          DVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAKQAGLRLSARMVFEH
MAV_2013|M.avium_104                ELLSTPEVG----RFDDFFALGGDSILSVQLASRARAAGLPVSPRMIFEN
MMAR_3691|M.marinum_M               ELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVFEH
MUL_3634|M.ulcerans_Agy99           ELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVFEH
MAB_2122|M.abscessus_ATCC_1997      ELLEISDVD----PEDNFFALGGDSVISIQWSTRAAERGLAMTPQMVFEC
MLBr_01996|M.leprae_Br4923          -------------VIDAWFTLG----MMFEMRSYAEYPTMALGVESVAEL
                                                   : :* **    :  :  : *    : .    : * 

Mb2401c|M.bovis_AF2122/97           PVLCELAAAVDAKP----------------------HVEAEPD-------
Rv2380c|M.tuberculosis_H37Rv        PVLCELAAAVDAKP----------------------HVEAEPD-------
TH_3141|M.thermoresistible__bu      PTLHELAAAVEAREAVEARETAEAGGAEAGGAESGGGADGAERGAAAGDS
Mvan_3845|M.vanbaalenii_PYR-1       PRLAELAAALDS----------------------GAGAAAEQP-------
MSMEG_4511|M.smegmatis_MC2_155      PVLSELAAAIDAAG----------------------EGSAAQD-------
Mflv_2696|M.gilvum_PYR-GCK          PVVHDLAVALDTAK-----------------------TPEVAD-------
MAV_2013|M.avium_104                PTVQQLAAALDALG--------------------DNDSDGRLDDQP----
MMAR_3691|M.marinum_M               MTIAELAAAVDAANGE---------------------PVVEAD-------
MUL_3634|M.ulcerans_Agy99           MTIAELAAAVDAANGE---------------------PVVEAD-------
MAB_2122|M.abscessus_ATCC_1997      ATIAQLAGAVDAADR----------------------VVTEGDSHL----
MLBr_01996|M.leprae_Br4923          AAPPESIRALLAHG------------------------------------
                                        :   *: :                                      

Mb2401c|M.bovis_AF2122/97           ---DKHHAPMSTSGLSPDELSALTASWDQWP----
Rv2380c|M.tuberculosis_H37Rv        ---DKHHAPMSTSGLSPDELSALTASWDQWP----
TH_3141|M.thermoresistible__bu      GNGAASHAPMSTSGLSAEQLSALTASWNPAGEDAP
Mvan_3845|M.vanbaalenii_PYR-1       ---DTHHAPMSVSGLSEDELAALTASWG-TGE---
MSMEG_4511|M.smegmatis_MC2_155      ----VHHAPMEASGLSSDELAALTAAWGQSQDGKR
Mflv_2696|M.gilvum_PYR-GCK          ----VRHDPMSASGLTPEELAMVATSWAAEQDGSP
MAV_2013|M.avium_104                --ADTRFEPMSTSGLSASDLAAVTQLWSSSREGTA
MMAR_3691|M.marinum_M               PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MUL_3634|M.ulcerans_Agy99           PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MAB_2122|M.abscessus_ATCC_1997      VTPPVQSAPMSASGLSADALAELTASWQAQS----
MLBr_01996|M.leprae_Br4923          -----CSQPLKYTGR--------------------
                                            *:. :*