For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3730 | - | - | 100% (2282) | linear gramicidin synthetase subunit D |
M. thermoresistible (build 8) | TH_3141 | - | e-134 | 32.77% (1236) | PUTATIVE amino acid adenylation domain |
M. thermoresistible (build 8) | TH_3072 | - | e-112 | 40.54% (661) | PUTATIVE peptide synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 0.0 | 49.02% (1020) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_2697 | - | 1e-180 | 36.22% (1237) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv0101 | nrp | 0.0 | 49.02% (1020) | peptide synthetase |
M. leprae Br4923 | MLBr_02353 | - | 1e-32 | 28.24% (478) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_4099c | - | 0.0 | 63.19% (2214) | non-ribosomal peptide synthetase |
M. marinum M | MMAR_0099 | - | 0.0 | 60.08% (2039) | non-ribosomal peptide synthetase |
M. avium 104 | MAV_3244 | - | 0.0 | 63.21% (2196) | linear gramicidin synthetase subunit D |
M. smegmatis MC2 155 | MSMEG_0402 | - | 0.0 | 70.54% (1979) | linear gramicidin synthetase subunit D |
M. ulcerans Agy99 | MUL_3633 | mbtF | 1e-178 | 35.91% (1306) | non-ribosomal peptide synthetase MbtF |
M. vanbaalenii PYR-1 | Mvan_3844 | - | 0.0 | 36.38% (1300) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M MTQPTKPVVDIEDVMTLSPLQLGLFALAMASGAASDDPYTVALGIDVHGS Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LDVGLLRSCALAMLKRHPNLRARFLGRGLPHPVQVVPSEVQLEWARVEAT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M AETAGALEAQERNRGFDLEMGPAIRFLLIELPGDRWRFLITAHHIVIGGW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M SIALFVDELLTLYEADCNIDTLPAQPRPYRDYIGWLERCDVEQGQRQWRE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M HLAGLAAPTLLAAPLGSSGVQPDSLPKRAELTLDEGATTSLVDGARSRGV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M TVNTLTQLAWALMLSMLTDRRDVVFGVTVSSRPAELARVESMVGLFVNTV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M PLRVRLDPKTTVAQQCALIQRDAARLREHAYLSHSQIRALAGMGELFDTL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LVFQNFPSLGLADGKARAVGAARFDSLTVQSPTHFPVCITAELTDARLSL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M SIATNANAFGDITESALGDRLVAVLQRLLPMWDRPLRDVSMLLDGQTDGD Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M TAVSEHARLDVVGNRAVLAEPLVEPVSVPGLFAAQVASRAEVTALVCGDR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M SLTYRELDRAANRLAHLLVDQGVGPGDVVGLLLERSVEAVIAILAVLKSG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M AAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGYPVAVIDIDDP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M AIATCYPGYGLPFPSADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M ATGFTPAPGQIWTQCHSYAFDYSVWEMWGALLHGGRLVVVPELVTRSAAE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LLALLVTEGVGVLSQTPSAFYALQAEDAAQPQLGRQLCLDAVVFGGEALE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M PARLGPWLANHGRRPRLINMYGITETTVHASFREIVRHDLGFAVSPVGVP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LANLAFFVLDGWLRPVPVGVAGELYVAGAGVGCGYWRRSGLTASRFVACP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M FGALGARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRIELGEVAAALS Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M QLDGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M AVVVVDSLPLTVNGKLDIRALPAPQYGATGSYRAPASPVEEVLAGIYAQV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3244|M.avium_104 -------------------------------------------------- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LGLDRVAVDQSFFDLGGDSLSAMRVVAAINKSLGGDLSVRALFDAPTVAE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 ---------------MLESEDRALPLSRGQLDIWLSQETGLVGAEWQLGL MAV_3244|M.avium_104 ----------------MARDDRAFPLTRGQLDIWLSQEAGFAGTQWQLGL TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M LAPGIGQGSGQWTPLVAGERPAVVPLSFAQQRLWFIDQLQGPSAVYNMAW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 LVRIEGQVERVLLERAIRQAVTEAEPARAAFFEVDGQIVQRPIDHSDLEL MAV_3244|M.avium_104 LVKIDGKVHRDALEQAITQAVAEAEPGRVSFFEVDGQVVQKPIDYPHVEL TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M SARLSGELDAAALGAAFADVVGRHESLRTVFRAVAGVAEQLVLGVEQVDV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 AFEDLRDSDDPAGLARKKATDIQRTLMPLTGQL-LKFALYRTADDEFHLF MAV_3244|M.avium_104 AFHDLTDHADPVAEAREMSSAIQRTPMPLNGQM-FKFVLFQTGHDEFYLF TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M RWQIIDAQGWSSRRLAAALEQQARHCFDLTVEIPLRASLFRVTDDEHVLV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 GLCHHINLDGLGMAVVSRRVASIYTALATGEP------IPPAYFGTLQDL MAV_3244|M.avium_104 GCCHHIAIDGLGMALVCRRVATIYSAMVAGKP------IPDAYFGTVQDL TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M VVAHHIAADGWSLRPLVTDLGVAYASRCAGRAPGWAGLAVQYVDYTLWQR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 VDWETDYVASAEYAEDREYWSNNLPPDSGLDYRMPH--ASEESDGYKPSD MAV_3244|M.avium_104 IDLESGYEASPDYAEDKAYWSEHLPPESGPVDRLPD--AEGERDHYSPSA TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M TNLGELTDSHSGIAGQLRYWEKALEGMAERLQLPTDRAYPRVADHRGSGV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 SVQMDDVTVSEIKELTKVLRIRRYSVITAACALLVRGWSTSGSEVALDFP MAV_3244|M.avium_104 SVQLDPSVANRIKELSKKLAIRRFSVTTAACALLVRGWSGSGSEVALDFP TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M DVQWPAQLQQQVARVAREHHATSFMVIQTALAVLLAKLSGS-SDVAVGVP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 VSRRVHPDSRTLPGMMAGVVPLVLNAPPQSTVAEFCRHVDTRIRELLQHQ MAV_3244|M.avium_104 VSRRVRPESKTLPAMLAGVVPLVLSTAPESTVADFCKHVDKRIRELLAHQ TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M VAGRGDPALDELVGVFVNTVVLRVQVAGDPTFAQLLAQVRTRSLAAFEHQ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 RFPVHTLEDEEFGLRGPRHAGNRVAVNFIPARLTLDLAGAPATASYTNHG MAV_3244|M.avium_104 RFPVHTLEGD-----GLRQAPNRVGINFIPSRLTLDLAGSPATASYTNHG TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M DVPFEVLVERLNPVRSLTHHPLVQVVLAWQNDMSAELVLDGLDVEFAPVH Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 PMGHFGLFFIGASDQLVLSSSGDGE---------PFARFGVPNLAVRLQR MAV_3244|M.avium_104 PVGHFGLFFLGAGDQLFLSTAGPGQ---------PFASFGVADLAGRLQQ TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M TQTARMDLVFSLGERFTDTGAPAGIGGGVEFRTDVFDAASIAALIQRLQR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 LLSEMAADPDRRLSSLDSLVNDELADLAELGNRAILTAPAARPVSIPELF MAV_3244|M.avium_104 ILAAMTEDPDRPLSSIELLTGDEPALIDRWSNRPALTEPAPAPVSIPQAF TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ---MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALF MMAR_0099|M.marinum_M VVVAMVADPDRRLSSVDLLDAAEHARLDVVGNRAVLAEPLVEPVSVPGLF Mb0104|M.bovis_AF2122/97 --------------------------------------MHRVRLSRSQRN Rv0101|M.tuberculosis_H37Rv --------------------------------------MHRVRLSRSQRN Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 TAQVSAEPDAVALTFGGSSLTYRELDEAADRLAIQLGHRGVGPGDRVILF MAV_3244|M.avium_104 AEHVQRTPDAVAVTFGATSLTYAQLDEASNRLGHLLADHGVGPGDCVAVM TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 AEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFL MMAR_0099|M.marinum_M AAQVASRAEVTALVCEDRSLTYRELDRAANRLAHLLVDQGVGPGDVVGLL Mb0104|M.bovis_AF2122/97 LYNGVRQDNNPALYLIGKSYRFRRLELAR----------------FLAAL Rv0101|M.tuberculosis_H37Rv LYNGVRQDNNPALYLIGKSYRFRRLELAR----------------FLAAL Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 SDRSARAVIGILAVLKTGAAYLPVDPAVPASRLEFIVSDAAPVAAITTTD MAV_3244|M.avium_104 FPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADAAPSAVITTSD TH_3730|M.thermoresistible__bu ---------------------------------------------VTTAE MSMEG_0402|M.smegmatis_MC2_155 IPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTAD MMAR_0099|M.marinum_M LERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAPVAVITTAG Mb0104|M.bovis_AF2122/97 HATVLDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSG Rv0101|M.tuberculosis_H37Rv HATVLDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSG Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 LRGRLDGFGLAVIDLDAHTDSPAEGQSGLVP-AAPAPDDIAYIIYTSGTT MAV_3244|M.avium_104 LRSRLDDHDLLVIDVH---DPAVEAQPGTAL-PWPAPENTAYIIYTSGTT TH_3730|M.thermoresistible__bu LGARLHRSGVPVIHID---DPAAPGQAGATTGPAPAPDDIAYIIYTSGTT MSMEG_0402|M.smegmatis_MC2_155 LRSRLDQYDLAVIDMA---DPAIDRRPSDAL-SGPRPDDLAYMTYTSGTT MMAR_0099|M.marinum_M LAQRLAGYPVAVIDID---DPAIATCYPGHGLPFPSADNIAYLIYTSGTT Mb0104|M.bovis_AF2122/97 ILGKPLVRHTVHTDPNG-YVTGLDVHTHHILLDGGATGTIEADLARYLTT Rv0101|M.tuberculosis_H37Rv ILGKPLVRHTVHTDPNG-YVTGLDVHTHHILLDGGATGTIEADLARYLTT Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 GAPKGVAVTHHNVTQLMQSLDA-GLP--KPGVWPLCHSLAFDVSVWEIWG MAV_3244|M.avium_104 GTPKGVAIPHLNVTWLIESLDA-GLP--PGNVWTQCHSSAFDFSVWEIFG TH_3730|M.thermoresistible__bu GVPKGVAVTHRNVAALLSALDA-ELA--SGQVWTQCHSLAFDFSVWEIWG MSMEG_0402|M.smegmatis_MC2_155 GVPKAVAVTHHNVTQLVSALHA-DLPSGPGQVWSQWHSLVFDVSVWEIWG MMAR_0099|M.marinum_M GKPKGVGITHHNITQLFTSVAATGFTPAPGQIWTQCHSYAFDYSVWEMWG Mb0104|M.bovis_AF2122/97 DPAGETPSVGAGLAKLREAHRR------ETAKVEESRGRLSAVVQRELAD Rv0101|M.tuberculosis_H37Rv DPAGETPSVGAGLAKLREAHRR------ETAKVEESRGRLSAVVQRELAD Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 ALLRGGRLAVVPESITASPADFHDLLVAEQVTVLTQTPSAVAMLSPDG-- MAV_3244|M.avium_104 ALLRGRRLLVVPESVASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEG-- TH_3730|M.thermoresistible__bu PLLYGGRVVIVPDPVVRSPEDLHALLAAEQVGMLSQTPSAFYALQTADSL MSMEG_0402|M.smegmatis_MC2_155 ALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEG-- MMAR_0099|M.marinum_M ALLHGGRLVVVPELVTRSAAELLALLVTEGVGVLSQTPSAFYALQAEDAA Mb0104|M.bovis_AF2122/97 EAYHGG----HGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQR- Rv0101|M.tuberculosis_H37Rv EAYHGG----HGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQR- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 -------LESTALAVVGEACPAAVVDKWAP----GRTMINAYGPTETTMC MAV_3244|M.avium_104 -------LESTALVVAGEACPTDVVDRWAAP---GRVMLDAYGPTETTVC TH_3730|M.thermoresistible__bu QPEQARQLQLQTVVFGGEALEPQRLSAWMRNHPERPRLINMYGITETTVH MSMEG_0402|M.smegmatis_MC2_155 -------LESTTLIVAGEACPTELVDRWAP----GRVMINAYGPTEATIY MMAR_0099|M.marinum_M QPQLGRQLCLDAVVFGGEALEPARLGPWLANHGRRPRLINMYGITETTVH Mb0104|M.bovis_AF2122/97 --------VPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVA Rv0101|M.tuberculosis_H37Rv --------VPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVA Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 VAISAPLKADLPDAVVPIGSPVPGAALFVLDTWLQPVPAGVVGELYVAGD MAV_3244|M.avium_104 ASISTPLTAG--DPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAGR TH_3730|M.thermoresistible__bu ASFREIGAADLDDNTSPIGRPLPHLAFFVLDGWLRPVPPGVVGELYVAGA MSMEG_0402|M.smegmatis_MC2_155 AAMSEPLTAG--TGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGH MMAR_0099|M.marinum_M ASFREIVRHDLGFAVSPVGVPLANLAFFVLDGWLRPVPVGVAGELYVAGA Mb0104|M.bovis_AF2122/97 TCLVNSVAQT---VRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRM Rv0101|M.tuberculosis_H37Rv TCLVNSVAQT---VRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRM Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 GVACGYVGRSDLTASRFVACPFGKPGTRMYRTGDLVLWGDDGQLQYLGRA MAV_3244|M.avium_104 GVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRA TH_3730|M.thermoresistible__bu GLATGYVSRSDLTSTRFVACPFGPPGTRMYRTGDLVRWDTGGELHYIGRA MSMEG_0402|M.smegmatis_MC2_155 GVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRA MMAR_0099|M.marinum_M GVGCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWGPDGQLQYVGRA Mb0104|M.bovis_AF2122/97 YLAINRTSHVEALTLNFIREPCAP-----------------GLRPFLSEV Rv0101|M.tuberculosis_H37Rv YLAINRTSHVEALTLNFIREPCAP-----------------GLRPFLSEV Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 DEQVKIRGYRIELGEVQAALGALDGVDQAAAIVREDRPGDKRLVGYVTGT MAV_3244|M.avium_104 DEQVKIRGFRIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGT TH_3730|M.thermoresistible__bu DEQVKIRGYRIELGEIQAALARLDGVDQAAVIAREDRPGDKRLVGYITGT MSMEG_0402|M.smegmatis_MC2_155 DEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT MMAR_0099|M.marinum_M DEQVKIRGYRIELGEVAAALSQLDGVDQAVVIAREDRPGDKRLVGYLVGS Mb0104|M.bovis_AF2122/97 PIATDIG--PVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERI Rv0101|M.tuberculosis_H37Rv PIATDIG--PVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERI Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 ADPAEIRGILSKRLPPYMVPAAVVVLETLPLTSNNKLDTRALPAPEYGGL MAV_3244|M.avium_104 ADPAELRAQLADRLPPYMVPTAVMVLDALPLTGNGKLDKRALPSPEYAAG TH_3730|M.thermoresistible__bu ADPVQARAQLADRLPPYMVPAAIVVLESIPLTSNNKLDVRALPAPEYRAT MSMEG_0402|M.smegmatis_MC2_155 ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSA MMAR_0099|M.marinum_M VDAGQARAALAQALPAYMVPAAVVVVDSLPLTVNGKLDIRALPAPQYGAT Mb0104|M.bovis_AF2122/97 AAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDS Rv0101|M.tuberculosis_H37Rv AAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDS Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 GADYRAPGNAVEEILAGVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR MAV_3244|M.avium_104 --EYRAPGDAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR TH_3730|M.thermoresistible__bu GAEYRAPGTPLEGLLAGIFAEVLGVERVGVDDSFFDLGGDSILSMQVVAR MSMEG_0402|M.smegmatis_MC2_155 ANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR MMAR_0099|M.marinum_M G-SYRAPASPVEEVLAGIYAQVLGLDRVAVDQSFFDLGGDSILAIQVVAR Mb0104|M.bovis_AF2122/97 ARGVHQFLGRRRFVYP--WVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIA Rv0101|M.tuberculosis_H37Rv ARGVHQFLGRRRFVYP--WVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIA Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 ARAAGVLCRPRDVFIEQTVSRLAAVAEVSG---GEAYVADEGLGTVAVTP MAV_3244|M.avium_104 ARAAGVICRPRDVFVEQTVARLARVSQVAVD--GELGAADEGIGPVRPTP TH_3730|M.thermoresistible__bu ARAAGVQCRPRDIFVEQTVARLASVVKVSG---GEPETVDDGTGAVVATP MSMEG_0402|M.smegmatis_MC2_155 ARAAGIQCRPRDIFVEQTVAGVARVAVAAG----ESHVVDEGVGPVVATP MMAR_0099|M.marinum_M ARAAGVVCRPRDVFTEQTVAGLATVAAVFDDANDDGGHAEDSVGEVVATP Mb0104|M.bovis_AF2122/97 CHLAGCGYSVCDTADEISVRTNAITEHGDG---ILVTVVDVAATQLAVVG Rv0101|M.tuberculosis_H37Rv CHLAGCGYSVCDTADEISVRTNAITEHGDG---ILVTVVDVAATQLAVVG Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 IMHWLRDVDGPIVEFNQTLVIQVP----SSVTQDDVVIVLQALLDRHPSL MAV_3244|M.avium_104 IMRWLQDIDGPIDEFNQTMVLAAP----AGVGVDDVAVVLQALLDRHPML TH_3730|M.thermoresistible__bu IMRWLRGVDGPTDQFNQTVVLQAPPGTDTAAAEADVVAVLQALIDRHPTL MSMEG_0402|M.smegmatis_MC2_155 IMRWLREVDGPTGQFNQTVITQAP----AGVTEDDVVVILQALLDRHATL MMAR_0099|M.marinum_M IMLWLQSLDGPLKEFNQTALLQAP----AAMSYGDVIVSLQAVLDRHAML Mb0104|M.bovis_AF2122/97 HDELRKVVDERVTQVTHDALLATK---------TAYIMPTSGTTGQPKLV Rv0101|M.tuberculosis_H37Rv HDELRKVVDERVTQVTHDALLATK---------TAYIMPTSGTTGQPKLV Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 RLRLQ----DN-DGDWSLLVPEAGAVDARDRLHVVGELSDEALVAARTAL MAV_3244|M.avium_104 RLRVQ----DDGAGGWSLEAPEVGSVRAADCLRAVDSLSDAALVEARSRL TH_3730|M.thermoresistible__bu RMRAEGMTAGDGTDDWSLFIPEPGATSAREVMHTVDTLTDEVLIAARSRL MSMEG_0402|M.smegmatis_MC2_155 RLRVEDT--QEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL MMAR_0099|M.marinum_M RLQVD----TDATGRWLLHVPAPGCVDARKCVRAVTALSDDELVQARSRL Mb0104|M.bovis_AF2122/97 RISHG-----------SLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVE Rv0101|M.tuberculosis_H37Rv RISHG-----------SLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVE Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 DPATGSMLSAVWVPGTAQLALVIHHLAVDGVSWRILLEDINIAWAQHHGG MAV_3244|M.avium_104 NVSDGVLLSAVWASETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHQGG TH_3730|M.thermoresistible__bu NPAAGVMLSAVWARGSGQLVLMIHHLAVDGVSWRILVEDLNIAWAQHRTG MSMEG_0402|M.smegmatis_MC2_155 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTG MMAR_0099|M.marinum_M DPSAGVMVSALWVTSSAQLALVIHHLAIDGVSWRILLDDLNSVWEQHRSG Mb0104|M.bovis_AF2122/97 EIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCA Rv0101|M.tuberculosis_H37Rv EIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCA Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 ADIELPAGGTSFARWSALLAEHALSTDVVEQAD--TWRQVLATPARVGTV MAV_3244|M.avium_104 QEIALPVPGTSFARWSSILAEYAKSPAVVAAAA--AWQQVVATPAVLPAV TH_3730|M.thermoresistible__bu QPIDLPANGTSFARWSALLADHARAPEVVEHVE--AWQRVIAAPSALPAI MSMEG_0402|M.smegmatis_MC2_155 QSIELPAGGTSFARWSALLAEHAKTDTVRDLAD--AWRAVTSVPQALPPV MMAR_0099|M.marinum_M EMAALPAGGTSFRRWAALLAEQAYSATAVDHAA--AWRQVLATPSVLPAV Mb0104|M.bovis_AF2122/97 DGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTE Rv0101|M.tuberculosis_H37Rv DGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTE Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 QPEIDTYANAGRLSVALDTETTRQLLGEVPAAFHAGVQDILLIAFGLAWN MAV_3244|M.avium_104 GPD-DTYASAGQLSASLDVETTRLLLGEVPAAFHAGVQDILLIAFGLACT TH_3730|M.thermoresistible__bu RPERDTYATAGQLSVSLDADTTRQLLGAVPAAFHAGVQDILLIAFGLAWA MSMEG_0402|M.smegmatis_MC2_155 QPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWT MMAR_0099|M.marinum_M KPAVDTYATAQRLLVSLDIETTRTLLAAAPAAFHAGVQDILLIAFALAWS Mb0104|M.bovis_AF2122/97 ATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADG Rv0101|M.tuberculosis_H37Rv ATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADG Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 EFLGVSGAPIAFDIEGHGRQEEIGEAVHRRIDLSRTTGWFTTKYPASLAV MAV_3244|M.avium_104 EFVGG-GAPIGIDVEGHGRHEEIASG----VDLSRTVGWFTTKYPVALRM TH_3730|M.thermoresistible__bu EFLGACDSPIGIDVEGHGRAEELAAG----VDLSRTVGWFTTKYPVALTI MSMEG_0402|M.smegmatis_MC2_155 EFLNRSDTPIGVDVEGHGRYDELASD----VDLSRTVGWFTTKYPVALTV MMAR_0099|M.marinum_M EFSSGGGSRIAIDVEGHGRHEELAFG----VDLSHTLGWFTTKYPVAVSV Mb0104|M.bovis_AF2122/97 YLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKIS Rv0101|M.tuberculosis_H37Rv YLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKIS Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 G-ELSWAQVSAGEAALGPVIKTAKEQLRALPDGLTYGLLRYLNPGVDLTG MAV_3244|M.avium_104 GRRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEIEVQG TH_3730|M.thermoresistible__bu P-KLSWEQVRTGGDALGAAVKAAKEQLRSVPDGITYGLLRHLNPDVELGG MSMEG_0402|M.smegmatis_MC2_155 E-NLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG MMAR_0099|M.marinum_M G-ALRWAQVVAGDAALGAVVKDAKEQLRGLPDGLLYGLIRYLNREVELAG Mb0104|M.bovis_AF2122/97 GKRVDIAEVTR-RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAA Rv0101|M.tuberculosis_H37Rv GKRVDIAEVTR-RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAA Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 PE----PTIGFNYLGRLGAGAGDLSEDFWRIS--ADSLRLTDVAAAISMP MAV_3244|M.avium_104 PD----PVIGFNYLGRLGAGA-DLSEEMWRVS--ADSLSSAAVATAVPMP TH_3730|M.thermoresistible__bu AE----PAIGFNYLGRLAAGAGDLPDELWRID--PSGLPITEAASKIPMP MSMEG_0402|M.smegmatis_MC2_155 SD----PTIGFNYLGRLGAGAGELSEELWRID--QDSLALSDAASAVPMP MMAR_0099|M.marinum_M AE----PTIGFNYLGRLSTRT-TAGDDHWQIARWGSLFTDECASAELPIQ Mb0104|M.bovis_AF2122/97 ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID-SDNLPRLPQWSAAGLN Rv0101|M.tuberculosis_H37Rv ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID-SDNLPRLPQWSAAGLN Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 LAHSVELNAGTMDT----------AAGPELRANWSWAPSALDGAQADRLS MAV_3244|M.avium_104 LAHTVELNAGTMDT----------DAGPQLHANWRWARSVLTDEQLNRLS TH_3730|M.thermoresistible__bu LAHTVEVNAGTLDAG---------PDGPVLQATWTWAPSLVDEAQIARLS MSMEG_0402|M.smegmatis_MC2_155 LMHTVELNAGTIDT----------DNGPSLRASWTWAPSAFDEEQATRLS MMAR_0099|M.marinum_M LFHTVELDAVTFDT----------EAGPQLHAQWTWATSALDRAQLNRIS Mb0104|M.bovis_AF2122/97 TAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYL Rv0101|M.tuberculosis_H37Rv TAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYL Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 RLWFEALAGICAHVRSGGGGLTPSDLAPARLNQPQIDALVQQYDISDVLP MAV_3244|M.avium_104 RLWFEALTGICAHVQAGGGGLTPSDIAPARLDQQQIDELCQQHQIADVLP TH_3730|M.thermoresistible__bu RLWFEALGGVCAHVRSGGGGLTPSDIAPARLTQQQIDELADRHDIADILP MSMEG_0402|M.smegmatis_MC2_155 RLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLP MMAR_0099|M.marinum_M RLWFEALTGICAHVRAGGGGMTPSDIGLTRLSQHQIDQLEQRYCVADVLP Mb0104|M.bovis_AF2122/97 GWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR---PAAIP Rv0101|M.tuberculosis_H37Rv GWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR---PAAIP Mflv_2697|M.gilvum_PYR-GCK ------------------------------------MTAAKTGAIADVMA Mvan_3844|M.vanbaalenii_PYR-1 --------------------------------MTQIQQSVEPPVIEDVLA MUL_3633|M.ulcerans_Agy99 -------------------------------------MTAAAPQIEDVLA MLBr_02353|M.leprae_Br4923 --------------------------------------MITPDNAIAVVG : MAB_4099c|M.abscessus_ATCC_199 LTPLQQGLLFQAGFAEATGDSTEDDVYAVQLALTLTGALDVARLHDAVSA MAV_3244|M.avium_104 LSPVQQGLLFHTGFAQEL-----EDLYAVQLGITVSGTLDPHRLRDAVQN TH_3730|M.thermoresistible__bu LTPVQQGLLFHSAVTRTT----ADDIYAVQLDLTIAGVVDQHRLRDAVHA MSMEG_0402|M.smegmatis_MC2_155 LTPVQQGLLFHSTFARGIG----DDVYAVQLDITITGVLDQHRLRDAVHT MMAR_0099|M.marinum_M LTPLQQGLLFHADAARGG-----ADLYVVQFDITLSGALDPRRLRTAAQE Mb0104|M.bovis_AF2122/97 LSFAQRRLWFLDQLQRPAP------VYNMAVALRLRGYLDTEALGAAVAD Rv0101|M.tuberculosis_H37Rv LSFAQRRLWFLDQLQRPAP------VYNMAVALRLRGYLDTEALGAAVAD Mflv_2697|M.gilvum_PYR-GCK LSPLQQGLYSLTAMSDG------DDPYLIGMSADITGALDVSLLHDCAAA Mvan_3844|M.vanbaalenii_PYR-1 LSPLQQGLFSMATLSEGRD----DDPYVIAMTADATGDLDARLLRECAAE MUL_3633|M.ulcerans_Agy99 LTPLQEGLFALHQLAEDG-----VDLYSMQFVVDIDGPVDLELLRRSAQA MLBr_02353|M.leprae_Br4923 MAGKFPGANDVSAFWTNLR----------RGKESIVTLSEQELRDNGVSD :: : . MAB_4099c|M.abscessus_ATCC_199 VAKRHPNLVARFS--EEYGEPVQIILADPVIAWQHVELIG------DIDQ MAV_3244|M.avium_104 AVNRHPNLVARFF--DEFGEPVQIIPAEPEMAWRYLELDGG-----DIDG TH_3730|M.thermoresistible__bu VVARHPNLAARFC--TDHDHPVQIIPTEPVAAWRYLDLRGDD---QNPEH MSMEG_0402|M.smegmatis_MC2_155 VVARHPNLAARFV--EQFGEPVQVLTADPMIAWRYLDLRGDD---LTPDH MMAR_0099|M.marinum_M VLRRHPNLAAQFVWGEPLDEPVQIILNDLVLEWRTVEFDPAGDPDAHVEQ Mb0104|M.bovis_AF2122/97 VVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWP------AD Rv0101|M.tuberculosis_H37Rv VVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWP------AD Mflv_2697|M.gilvum_PYR-GCK VLARHPNLRAGFFQ-GDLKRPVQVIPEKVEVLWRHVRCDG---------T Mvan_3844|M.vanbaalenii_PYR-1 LLDRHANLRASFVK-GNLSRAVQVIPKRVDLPWRHVTVAGD--------A MUL_3633|M.ulcerans_Agy99 MLDRHPNLRAAFWD-RDVPKPVQIVPVHAALPWS-ERVATP--------A MLBr_02353|M.leprae_Br4923 KALADPAYVRRAPLLDGIDEFDADFFGLPPLAAQVLDPQHR--------- . . MAB_4099c|M.abscessus_ATCC_199 QVEQLCAAERAAVCRLFTEPVFRAALISGLG-GAEDGEVGKHRLVLTAHH MAV_3244|M.avium_104 QLEQLSADERAAVCDLAGQPAFRAALIR----IADD----RHRLLLTIHH TH_3730|M.thermoresistible__bu EVQQLCAAERAAVRDLTERPTFRAALIR----TGAT----EHRFVLTVHH MSMEG_0402|M.smegmatis_MC2_155 EIEQLCAAERSAVCDLLERPTFRAALIR----TSGN----QHRFVLTFHH MMAR_0099|M.marinum_M HIDEVCADERVAVADLGGGSPFRIALIR----TAPC----EHRLVLTAHH Mb0104|M.bovis_AF2122/97 RLQRAIEEAARHSFDLATEIPLRTWLFR----IADD----EHVLVAVAHH Rv0101|M.tuberculosis_H37Rv RLQRAIEEAARHSFDLATEIPLRTWLFR----IADD----EHVLVAVAHH Mflv_2697|M.gilvum_PYR-GCK EVEPLEREERARRFDLGRGPAMRFLLLETGQ--------QRWRFVITAHH Mvan_3844|M.vanbaalenii_PYR-1 ELEAAERLERTTPFTLARGPVIRFLLIEAP---------QRWRFVVTAHH MUL_3633|M.ulcerans_Agy99 EFDSIARSERRRPFDLSRGPALRVVVLSVPGE-------TKRRMIFTAHH MLBr_02353|M.leprae_Br4923 ---LFLQCAWHALEDAGCDPAQFDGSIG---------------------- : MAB_4099c|M.abscessus_ATCC_199 IVIDGWSLPILLQEIFSIYYG-------HQLPAPAPYRNFVTWLAGQD-- MAV_3244|M.avium_104 IVIDGWSLPVLLQEVFAGYYG-------QRLPAPPSYRSYLMWLSAQD-- TH_3730|M.thermoresistible__bu IVIDGWSLPILLQEIFAGYFG-------QRLPAPARFRDFVTWLAAQD-- MSMEG_0402|M.smegmatis_MC2_155 IVIDGWSLPILLQEIFAGYFG-------HRLPAAAPYRNFVNWLATQD-- MMAR_0099|M.marinum_M IVCDGWSMPIVMQEILAAYAG-------QPLAAPGSYRNFLTWLAERD-- Mb0104|M.bovis_AF2122/97 IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGD Rv0101|M.tuberculosis_H37Rv IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGD Mflv_2697|M.gilvum_PYR-GCK IVIDGWSLSLLVSELLALYRAAG--NTSALPDAPRPYRDYIGWLAARD-- Mvan_3844|M.vanbaalenii_PYR-1 ILIDGWSLPLFMGELLTLYRAGG--DVTALPDPPRPYRDYIGWLAGRD-- MUL_3633|M.ulcerans_Agy99 ILVDGWSLAVFFTELLAVYRAGG--AADALP-AARPYRDYIVWLANQD-- MLBr_02353|M.leprae_Br4923 VYGTSSPSGYLLHNLLSHRDP------HTVLAEGLNFDQFSLFLQNDK-- : . . . :: : : .: : MAB_4099c|M.abscessus_ATCC_199 -------RVAAQSVWGRALDGFEAPTLVGSLATA-----GRRGVESYRIS MAV_3244|M.avium_104 -------RAAAQDAWREALAGFETPTLVAPPGKI-----GRRAVATYTVS TH_3730|M.thermoresistible__bu -------RDAARAAWRELLDGFDTPTLIAPPGQA-----GPRGSASYRID MSMEG_0402|M.smegmatis_MC2_155 -------ATAAKAAWREVLDGFETPTLVAPPGVP-----GPRGIESYRVS MMAR_0099|M.marinum_M -------KSAARTAWRELFADFRHPTLVGLPDHLG---LGSRGVESYLLP Mb0104|M.bovis_AF2122/97 LDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP Rv0101|M.tuberculosis_H37Rv LDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP Mflv_2697|M.gilvum_PYR-GCK -------QDHARSLWRAHLADLDGPTLLAPALGAATIGDGLPGMVELTAD Mvan_3844|M.vanbaalenii_PYR-1 -------EETGRALWRRHLAGVDGPTLLTPALTSSAPTPGRPRLTEVRLD MUL_3633|M.ulcerans_Agy99 -------RSAALAGWMDYLRGVSEPLMVAYEATAGQSKPGK---TELLLP MLBr_02353|M.leprae_Br4923 ---------DFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSG .. MAB_4099c|M.abscessus_ATCC_199 EDITRSLGELARAQHTTVNTVLQAAWAQVLTWLTGQHDVAFGTAVSGRPA MAV_3244|M.avium_104 ADTTKALGELARSSRTTVSTVLQGAWAQLLTWLTGQHDVAFGTAVSGRPT TH_3730|M.thermoresistible__bu TETTAAIGELARTQRTTVNTVLQAAWAHLLMAMTGQRDVVFGTAVSGRPA MSMEG_0402|M.smegmatis_MC2_155 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPA MMAR_0099|M.marinum_M IGITEALTELARSCRVTVNIVLQAAFAQLLSWLTGQHDVAFGTTVSGRPA Mb0104|M.bovis_AF2122/97 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-- Rv0101|M.tuberculosis_H37Rv ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-- Mflv_2697|M.gilvum_PYR-GCK PSITEAVVDAARARGVTVNSLVQLAWALTLSSLTDRDDITFGVTVSGRPD Mvan_3844|M.vanbaalenii_PYR-1 AETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFGVTVSGRPG MUL_3633|M.ulcerans_Agy99 AADTARLRQWAGRHGLTLNTTVLFAWAVVLSRLTDRRDVVFGTVVSGRPD MLBr_02353|M.leprae_Br4923 ECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVFGSGV : . *: . : * MAB_4099c|M.abscessus_ATCC_199 DLAGADSMVGLLINTVPVRANITAATTVADLLDQLQRMHNDTVEHEHLAL MAV_3244|M.avium_104 ELPGADAMVGLLINTVPVRADIAAATTVVDLLEQLQRAHADTLEHEHLAL TH_3730|M.thermoresistible__bu DLPGADRIVGLLINTIPVRARIGADTTVADLLAQLQHAHNDTLEHEHLAL MSMEG_0402|M.smegmatis_MC2_155 DLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLAL MMAR_0099|M.marinum_M EVAGVHSMVGLFINTVPTRARMASTTTTRELLDQLQSVHYETLEHHHLAL Mb0104|M.bovis_AF2122/97 SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPF Rv0101|M.tuberculosis_H37Rv SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPF Mflv_2697|M.gilvum_PYR-GCK DLAGVESMIGLFVNTVPLRVRLDPALTAGAQCRALQQDAATLRDHSYLGH Mvan_3844|M.vanbaalenii_PYR-1 ELAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAALRDHGYLSH MUL_3633|M.ulcerans_Agy99 QLLGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSL MLBr_02353|M.leprae_Br4923 ALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMG-YAAPNPAAQADVI . . : . : : : : MAB_4099c|M.abscessus_ATCC_199 NEIHHAIG------LDRLFDTLFVYENYPIDAD---ALLGARELGITDFS MAV_3244|M.avium_104 NEIHRVTG------HDQLFDTLFLYENYPIDAS---ALLDVHELAVTEFS TH_3730|M.thermoresistible__bu TEIHHLAG------HDQLFDTLFLYESYPIDTG---AFSGAQELAVTGFT MSMEG_0402|M.smegmatis_MC2_155 NDIHHVSG------HEQLFDTLFLYESYPIDTS---AFMGVQELAVTEFN MMAR_0099|M.marinum_M SDIHRVSG------HDQLFDTLFVYENYPIDKT---AAQGTGELAISGIG Mb0104|M.bovis_AF2122/97 EVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN-LGDLQATPMPIDTRT Rv0101|M.tuberculosis_H37Rv EVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN-LGDLQATPMPIDTRT Mflv_2697|M.gilvum_PYR-GCK AELRALAG------VGELFDTLLVYENFPPGAVAGAGTLEAAGATFTPVA Mvan_3844|M.vanbaalenii_PYR-1 SELRALGG------IGELFDTLLVYENFPPGGLVGQARFEANGATFVPSA MUL_3633|M.ulcerans_Agy99 SEIQREHG------RGPLFDSLFVFENAPIDDAIRPAT-TPDGAQFLPVE MLBr_02353|M.leprae_Br4923 AEAHAVAG---------IDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEV : . . : . MAB_4099c|M.abscessus_ATCC_199 SREYNHYPLSVVAMPGNE---LSLRVEFDTDVFDSAEIDTVVDKLRQVLA MAV_3244|M.avium_104 SREFNHYPLSVVATPGHE---LSLRVEYDTEVFDEAGIETLIERLRQVLA TH_3730|M.thermoresistible__bu NREFNHYPLSVMALPGHE---LGLRIEYDTEVFDTAAIDALADRFRRVLE MSMEG_0402|M.smegmatis_MC2_155 NREYNHYPLSVMALPGHE---LGLRVEYDTSVFDVSEIETLIDRFQRLLE MMAR_0099|M.marinum_M CREYSHYPLVVQAMPGDQ---LGLRVEFRTDVFDAASIAALIQRLQRVVV Mb0104|M.bovis_AF2122/97 ARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLV Rv0101|M.tuberculosis_H37Rv ARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLV Mflv_2697|M.gilvum_PYR-GCK LQSLAHFPVTIAAHLTDGR--LTVLVEAKDGALGQITPRALGTRLLATVS Mvan_3844|M.vanbaalenii_PYR-1 LESLSHFPVTIAAHLADDE--LTVFVEVIDGALGALRPGDLGRRVLHTAQ MUL_3633|M.ulcerans_Agy99 MESLTHYPLTVVSHLREDE--LLVLIEAIAEALPYLPAAEIGERMLTVLR MLBr_02353|M.leprae_Br4923 SQIPRPGPCVLGSVKSNIG---HLEVAAGIAGLIKTILCLKNKAIPATLH . . : : . MAB_4099c|M.abscessus_ATCC_199 AMTVDPATRLSSIDLLDAGEH-----DRLDKWGNRAVLIRPEPALTSIPE MAV_3244|M.avium_104 AMTTDPGQRLSAIDLLDAAEH-----ERLDAWGNRAVLTRRPAAQASIPA TH_3730|M.thermoresistible__bu SMVGDPARRLSAIEVLDAAER-----EQLDAWSNRAVLADS-PALESIPE MSMEG_0402|M.smegmatis_MC2_155 AMIDDPARRLSSMDVVDDDER-----TQLDEWANRAVLTQPVDSPQSIPE MMAR_0099|M.marinum_M AMVADPDRRLSSVDLLDAAEH-----ARLDVVGNRAVLAEPLVEPVSVPG Mb0104|M.bovis_AF2122/97 AVAAAPERTVSSIDALDGTER-----ARLDEWGNRAVLTAPAPTPVSIPQ Rv0101|M.tuberculosis_H37Rv AVAAAPERTVSSIDALDGTER-----ARLDEWGNRAVLTAPAPTPVSIPQ Mflv_2697|M.gilvum_PYR-GCK RIVEGWDRPLREISISPDDHP-----VPVPVSEAAPTPSPSTGVHTRFTE Mvan_3844|M.vanbaalenii_PYR-1 RLISCWDAPLRSVGVLLPAEH-----TPAPMVREPLTAN---SIHDRFAG MUL_3633|M.ulcerans_Agy99 QLPDIGDGTPDDLDIRTAAEL-----KAHGLLAARSAPTFDTTVWEMFER MLBr_02353|M.leprae_Br4923 YTSPNRELRLDQTPFVVQSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEE . . MAB_4099c|M.abscessus_ATCC_199 LFAAQVARAPEAIAITCGERSWSYGELDATANRLANHLVTHGARPGERVA MAV_3244|M.avium_104 LFAAQVARAADAVAITCGERSFTYREVEESANRLAHLLSGQGAGPGQRVA TH_3730|M.thermoresistible__bu VFARQVARDPGAVAVTFEGRSMTYGELDDAATELANLLAVYGAGPGESVA MSMEG_0402|M.smegmatis_MC2_155 VFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVA MMAR_0099|M.marinum_M LFAAQVASRAEVTALVCGDRSLTYRELDRAANRLAHLLVDQGVGPGDVVG Mb0104|M.bovis_AF2122/97 MLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVA Rv0101|M.tuberculosis_H37Rv MLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVA Mflv_2697|M.gilvum_PYR-GCK TASARLGSVALSWDGG----ALTYRQLDEAADRLAAVLTASGVRTETPVA Mvan_3844|M.vanbaalenii_PYR-1 IAGDRLGSVALTWEAGGDSGTLTYRQLDEAADRMAVALTAAGVGPETSVA MUL_3633|M.ulcerans_Agy99 QVQTTPDAVALAAAGG---VRHTYAELHARACRLAGELAEHGVGPETVVA MLBr_02353|M.leprae_Br4923 ASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLSDVA . . : :* * *. *. MAB_4099c|M.abscessus_ATCC_199 LLLPRTGEAIAAILAVLKTG--AAYLPIDPAHPDSRVDFVLGDAAPIVAV MAV_3244|M.avium_104 VVIPRSAEAVVAIFAVLKTG--AAYVPIDPGVPAARLQFVLADSAPVAAV TH_3730|M.thermoresistible__bu LLMPRSADAIVAILAVLKTG--AAYLPIDPAVPAARLEFMLSDAEPIVAL MSMEG_0402|M.smegmatis_MC2_155 LMVPRSADAIVAILAVLKTG--AAYLPIDPSVPAARLEFMLGDAKPVAAV MMAR_0099|M.marinum_M LLLERSVEAVIAILAVLKSG--AAYLAIDVNHPDGRIGFMIEDAAPVAVI Mb0104|M.bovis_AF2122/97 LLFERCAPAVVAMVAVLKTG--AAYLPIDPANPPPRVAFMLGDAVPVAAV Rv0101|M.tuberculosis_H37Rv LLFERCAPAVVAMVAVLKTG--AAYLPIDPANPPPRVAFMLGDAVPVAAV Mflv_2697|M.gilvum_PYR-GCK VRLRRGADYVVAMFAVLKAG--GAIVPLDPAMPADRIEVILRRAG----- Mvan_3844|M.vanbaalenii_PYR-1 VLLSRGPDYVVTMLGVLKAG--GVIVPLDPAMPAERISDILEQSR----- MUL_3633|M.ulcerans_Agy99 LVLPRSERSIVAILGVLAAG--GAYLPVDVTLPSARVESIVRQASPALAI MLBr_02353|M.leprae_Br4923 YTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAA . :: .*: .. : : : MAB_4099c|M.abscessus_ATCC_199 TTAELLPRLSASGVPVIDIDDPAVS-AQNDTTLPVPA---VDDIAYIIYT MAV_3244|M.avium_104 TTAEVRDRLDGFTGQIIDFDDPAVA-EQPATGLPVPA---ADNIAYIIYT TH_3730|M.thermoresistible__bu TTVELGTRFNGTGVPIIEVDDPAPP-MYPSSTLLPPA---PDDIAYLIYT MSMEG_0402|M.smegmatis_MC2_155 TTGDLRSRFDGFDLQVVEVDDPAVE-IYPSTTLLTPS---PDDIAYMIYT MMAR_0099|M.marinum_M TTAGLAQRLAGYPVAVIDIDDPAIATCYPGHGLPFPS---ADNIAYLIYT Mb0104|M.bovis_AF2122/97 TTAGLRSRLAGHDLPIIDVVDALAA--YPGTPPPMPA---AVNLAYILYT Rv0101|M.tuberculosis_H37Rv TTAGLRSRLAGHDLPIIDVVDALAA--YPGTPPPMPA---AVNLAYILYT Mflv_2697|M.gilvum_PYR-GCK ------------VTVVVDEDTVARAT-AEPPAQYRPAETLPGQAAYVVFT Mvan_3844|M.vanbaalenii_PYR-1 ------------ASVVVDDAFVAAVPDVEPPAGYRPAEVTADRAAYIVFT MUL_3633|M.ulcerans_Agy99 TEADYSQLVGTAVPTLALDDPAAVDSISRRSAAAPTVDRRPEQSAYVIFT MLBr_02353|M.leprae_Br4923 SITTLGSDRVVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAM . .: MAB_4099c|M.abscessus_ATCC_199 SGTTGAPKGVAVTHRNVAQLLESLDAE-LALG--QVWTQCHS----LAFD MAV_3244|M.avium_104 SGTTGIPKGVAIPHRNVTLLLETLDAQ-LGLG--QVWTQCHS----LAFD TH_3730|M.thermoresistible__bu SGTTGVPKGVAITHANVTRVLHTLPAD-LPAGPGKVWSQWHS----LVFD MSMEG_0402|M.smegmatis_MC2_155 SGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGAVWSQWHS----LVFD MMAR_0099|M.marinum_M SGTTGKPKGVGITHHNITQLFTSVAATGFTPAPGQIWTQCHS----YAFD Mb0104|M.bovis_AF2122/97 SGTTGEPKGVGITHRNVTRLFASLPAR---LSAAQVWSQCHS----YGFD Rv0101|M.tuberculosis_H37Rv SGTTGEPKGVGITHRNVTRLFASLPAR---LSAAQVWSQCHS----YGFD Mflv_2697|M.gilvum_PYR-GCK SGTTGEPKGVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTF Mvan_3844|M.vanbaalenii_PYR-1 SGTTGRPKGVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLRVGHAWSFTF MUL_3633|M.ulcerans_Agy99 SGSTGEPKGVAGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSF MLBr_02353|M.leprae_Br4923 DDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIG .. . . . : MAB_4099c|M.abscessus_ATCC_199 YSVWEIWGALLYGGRLLVVPDAVVRSPEELHALLVSEEVSVLSQTPSAFY MAV_3244|M.avium_104 FSVWEIFGALLHGGRLVIVPDDIVRSPEDLHALLVREQVSVLSQTPSAFY TH_3730|M.thermoresistible__bu VSVWEIWGALLHGGRLVIVPESITGSPDDLHDLLVAEHVDVVYQTPSAAG MSMEG_0402|M.smegmatis_MC2_155 VSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVR MMAR_0099|M.marinum_M LSVFEMWGALLHGGRLVVVPESVTGSPADLHALLVAEQVDVLAQTPSAVA Mb0104|M.bovis_AF2122/97 ASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVA Rv0101|M.tuberculosis_H37Rv ASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVA Mflv_2697|M.gilvum_PYR-GCK DAAWQPLAALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSMFA Mvan_3844|M.vanbaalenii_PYR-1 DAAWQPLAALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFA MUL_3633|M.ulcerans_Agy99 DASWQPMVGLLDGHEIHLFDADEMRDADRLVEGIAIGQIDMIDTTPSMFV MLBr_02353|M.leprae_Br4923 YSTGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDIT : : . * * : : : * MAB_4099c|M.abscessus_ATCC_199 ALQTADALQPEMGQQLKLQTVVFGGEALEPQRLSSWFDSHPGLP-RMINM MAV_3244|M.avium_104 ALQSADALAPELGQQLKLQTVVFGGEALEPHRLATWLHRHPGLP-RMINM TH_3730|M.thermoresistible__bu MLS---------QRGLDSTALVVAGEACPTDLVDRWAPGR-----VMINA MSMEG_0402|M.smegmatis_MC2_155 MMS---------PEGLEGTALVVAGEACPTEVVDRWAVDR-----VMINA MMAR_0099|M.marinum_M MLS---------TQGLESTTLVVGGEACPAEVVDNWAPGR-----MMVNQ Mb0104|M.bovis_AF2122/97 MLP---------TQGLESVALVVAGEACPAALVDRWAPGR-----VMLNA Rv0101|M.tuberculosis_H37Rv MLP---------TQGLESVALVVAGEACPAALVDRWAPGR-----VMLNA Mflv_2697|M.gilvum_PYR-GCK RLRDVG-----LLSTVPLAVLALGGEAVDPGLWQQIRQECARTGMSAFNC Mvan_3844|M.vanbaalenii_PYR-1 QLHDVG-----LLSTVPLAVLALGGEAVSPATWRLIGDECARTGMTAFNC MUL_3633|M.ulcerans_Agy99 QLSAAG-----LLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNC MLBr_02353|M.leprae_Br4923 EYLAEYS-----AKGVELSAVNDPGNCVVAGPKDQIRAFS-----QRLDE .: *:. . : MAB_4099c|M.abscessus_ATCC_199 YGITETTVHASFREIDDGDVDSNSSPIGVPLEHLAFFVLDGWLRKVPVGV MAV_3244|M.avium_104 YGITETTVHASFREIVDADVDSSVSPIGVPLANLAFFVLDGWLRPVPVGV TH_3730|M.thermoresistible__bu YGPTETTMCVAISAPLTP--GSGAVPIGTPVPRAALFVLDSWMRPVPAGV MSMEG_0402|M.smegmatis_MC2_155 YGPTESTIYAAISAPLSP--GSDVVPIGSPVPKGATFVLDEWLRPVPPGV MMAR_0099|M.marinum_M YGPSETTMYVSMSAPLVP--GSGPAPIGVPVPRAALFVLDGWLRPVPAGV Mb0104|M.bovis_AF2122/97 YGPTETTICAAISAPLRP--GSGMPPIGVPVSGAALFVLDSWLRPVPAGV Rv0101|M.tuberculosis_H37Rv YGPTETTICAAISAPLRP--GSGMPPIGVPVSGAALFVLDSWLRPVPAGV Mflv_2697|M.gilvum_PYR-GCK YGPTETTVEAVVAEIGAHE----RPTIGRPTAPTRAYVLDSWLRPVPSGA Mvan_3844|M.vanbaalenii_PYR-1 YGPTETTVEAVVAPIDGYQ----RPSIGQPTRTMRTYVLDAWLRPVPDGV MUL_3633|M.ulcerans_Agy99 YGPTEMTVEAVVAAVKDYR----KPTIGTANAGTFGYVFDSALRMVPDGV MLBr_02353|M.leprae_Br4923 VGIPVRRVRATHAFHTSS----MEPMLREFSEFLSRQQLRVPNTPLLSNL * . : . : : : . MAB_4099c|M.abscessus_ATCC_199 VGELYVAGSGQASGYLGRSDLTTTRFVACPFGAPGSRMYRTGDLVQWG-- MAV_3244|M.avium_104 VGELYVAGGGLATGYVGRPGLSATRFVACPFGGPGARMYRTGDLVRWG-- TH_3730|M.thermoresistible__bu IGELYVAGDGVAVGYVGRSELTASRFVACPFGPPGSRMYRTGDLVRWG-- MSMEG_0402|M.smegmatis_MC2_155 VGELYLAGRGVGVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWG-- MMAR_0099|M.marinum_M AGELYVAGAGVGCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWG-- Mb0104|M.bovis_AF2122/97 AGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWR-- Rv0101|M.tuberculosis_H37Rv AGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWR-- Mflv_2697|M.gilvum_PYR-GCK AGELYLAGGQLTRGYLGRPGETAARFVPDPFV-PGARMYRTGDVVRRA-- Mvan_3844|M.vanbaalenii_PYR-1 AGELYLSGRQLTRGYLGRAAETAGRFVADPFT-PGQRMYRTGDVVRRG-- MUL_3633|M.ulcerans_Agy99 VGELYLSGAQLARGYVGRPGMTAARFVADPLR-PGQRMYRTGDLVRRL-- MLBr_02353|M.leprae_Br4923 TGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSL * * : **. . :: MAB_4099c|M.abscessus_ATCC_199 EDGQLRYVGRADKQVKIRGYRIELGEVHAALARVAGVDQAAVIAREDRPG MAV_3244|M.avium_104 ADGQLQYMGRADAQVKIRGYRIELGEIQAALAGLDGVEHAAVIAREDRPG TH_3730|M.thermoresistible__bu ADGQLQYLGRADEQVKIRGYRIELGEVQTALTAVDGVENAVVIAREDRPG MSMEG_0402|M.smegmatis_MC2_155 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPG MMAR_0099|M.marinum_M PDGQLQYVGRADEQVKIRGYRIELGEVAAALSQLDGVDQAVVIAREDRPG Mb0104|M.bovis_AF2122/97 ADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPG Rv0101|M.tuberculosis_H37Rv ADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPG Mflv_2697|M.gilvum_PYR-GCK VDGTLAFLGRSDTQVKIRGFRVEPGEVAAVLRTHPAVGQAYVAVRPHRDG Mvan_3844|M.vanbaalenii_PYR-1 ADGGLQFLGRADNQVKIRGFRVEPGEIAAVLSGHPAVTDAHVVVDRVGTQ MUL_3633|M.ulcerans_Agy99 SHGGYAYVGRADTQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDR MLBr_02353|M.leprae_Br4923 TGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWA . . :. : :* * :: .: . MAB_4099c|M.abscessus_ATCC_199 DKRLVGYITESTAGTLDPTAVRATLAERLPSYMVPAAVVVLDALPLTVNG MAV_3244|M.avium_104 DKRLVGYITG----TADPAEVRAQLGERLPGYMVPSAVVVLDALPLTVNG TH_3730|M.thermoresistible__bu DKRLVGYITG----TADPDQARARLADRLPAYMVPTAVVVLDALPLTVNG MSMEG_0402|M.smegmatis_MC2_155 DKRLVGYITG----TADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNG MMAR_0099|M.marinum_M DKRLVGYLVG----SVDAGQARAALAQALPAYMVPAAVVVVDSLPLTVNG Mb0104|M.bovis_AF2122/97 DKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG Rv0101|M.tuberculosis_H37Rv DKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG Mflv_2697|M.gilvum_PYR-GCK -HRLTAYVTGE----PQLRELRAWLGRRLPRYLMPNAIVAVDRIPLTAHG Mvan_3844|M.vanbaalenii_PYR-1 -TRLIAYVAAAT--PPAVADLRELMAKRLPRYMVPQRVVVLDELPLTSHG MUL_3633|M.ulcerans_Agy99 -TSLVGFVVWQDNMHEDLIKLRAGLTERLPSYMVPARIVTLPRLPVNANG MLBr_02353|M.leprae_Br4923 PQRSV---------MPHLVSLPGYPFARQRHWVEPRYTIWAQIPGASSGS :: * : . . MAB_4099c|M.abscessus_ATCC_199 KLDTRALPAPEFQ-----DADHYRAPEDAVEEILAGIYAQVLGVEQIGVD MAV_3244|M.avium_104 KLDTRALPAPEYS-----DVDRYRAPVTAIEEILADIYAQVLGVERVGVD TH_3730|M.thermoresistible__bu KLDTRALPAPEYQ-----DAEQYRAPTHAVEEVLAGIYAEVLGIDKVGVD MSMEG_0402|M.smegmatis_MC2_155 KLDRRALPAPEYQ-----SAQRYRAPETETEKTLAGIFAHVLGVERIGLD MMAR_0099|M.marinum_M KLDIRALPAPQYG-----ATGSYRAPASPVEEVLAGIYAQVLGLDRVAVD Mb0104|M.bovis_AF2122/97 KLDHRALPAPEYG-----DTNGYRAPAGPVEKTVAGIFARVLGLERVGVD Rv0101|M.tuberculosis_H37Rv KLDHRALPAPEYG-----DTNGYRAPAGPVEKTVAGIFARVLGLERVGVD Mflv_2697|M.gilvum_PYR-GCK KIDEPALVALEP-----AADGAATRPQTPTEVELAAVLAEVLGVGEIDVT Mvan_3844|M.vanbaalenii_PYR-1 KIDEAALAGIA------VEDAPSAAPETPTETALVELMAEVLGDDGIDVE MUL_3633|M.ulcerans_Agy99 KLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHID MLBr_02353|M.leprae_Br4923 PVDSSVDSATVEG---------VRGGESQTEATLQRIWSQCLGVSSVDRN :* . * : : . *. MAB_4099c|M.abscessus_ATCC_199 DSFFDLGGDSISSMQVVARAR-AAGLLLRPRDIFVEQTVSRLAQVAVFAD MAV_3244|M.avium_104 DSFFDLGGDSILSMQVVARAR-AAGVICRPRDVFTEQTVARLARVATVAT TH_3730|M.thermoresistible__bu DSFFDLGGDSISSMQVVARAR-AAGLTIRPRDIFVERTVARLAQVAVPTG MSMEG_0402|M.smegmatis_MC2_155 DSFFDLGGDSISAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDA MMAR_0099|M.marinum_M QSFFDLGGNSILAMRVSSAIEKFLGVDLPVRLMFEAPTVESLSRQVESPY Mb0104|M.bovis_AF2122/97 DSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLG--- Rv0101|M.tuberculosis_H37Rv DSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLG--- Mflv_2697|M.gilvum_PYR-GCK ADFLELGLDSIVALSVVQTAR-RRGVVMRAKLMLDCATVRELAAAIDDAG Mvan_3844|M.vanbaalenii_PYR-1 ADFLEMGLDSIVALTLVQAAR-RRGLEMRARLMLECNTIRELATAIDSGA MUL_3633|M.ulcerans_Agy99 DDLFLFGMDSIVAISLVHKAR-RQGLRVDPRMVLTATTIRQLGAAIDAAV MLBr_02353|M.leprae_Br4923 ANFFDLGGDSLMAISISMAAA-NEGMTITPQDMYEHPTLASLTAAVDASF .:: :* :*: :: : . : : : * MAB_4099c|M.abscessus_ATCC_199 GEAT---VVDAGTGPVVATPIIRWLHGLGGNVGEFNQTVVLQAPEGVSED MAV_3244|M.avium_104 GDDD---VVDEGTGRVVATPIMRWLQNMDGPVEQFNQTMVLAAPAGVTPD TH_3730|M.thermoresistible__bu ADAA---VDDAGTGPVVATPIMRWLYDTRGPIDQFNQTVVLRAPAGVTEA MSMEG_0402|M.smegmatis_MC2_155 GER-----TDRVSFAAVHGSDVTEVHARDLTLDKFIDAPTLRTATTLPRP MMAR_0099|M.marinum_M SSVE---LAPVELLKQGAGTPLFCLPPGGG------LSWIYRNLGAYLDC Mb0104|M.bovis_AF2122/97 RDAR---PTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGP Rv0101|M.tuberculosis_H37Rv RDAR---PTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGP Mflv_2697|M.gilvum_PYR-GCK SGPP----SADEGSGPIALLPNAHWLYEFGDPRRLASTEALRLPRGITGP Mvan_3844|M.vanbaalenii_PYR-1 HDHAPA-AVTDDRFGEVMPAPIMSWMYECGNYRRFTQNVLVSLPADITDS MUL_3633|M.ulcerans_Agy99 DSQD---APADADYGAVLPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRS MLBr_02353|M.leprae_Br4923 ASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRWRVPLILRLDPKIGSD MAB_4099c|M.abscessus_ATCC_199 DVVTVLQALLDRHATLRLRAEEN-----------------DGEWALLIPE MAV_3244|M.avium_104 DVAAVLQALLDRHAMLRLRVEDDG----------------AGGWSLEVPE TH_3730|M.thermoresistible__bu DVVEILQAVLDRHAMLRLRAADV--------------------ENLTVPE MSMEG_0402|M.smegmatis_MC2_155 DGAVQTVLLTGATGFL---------------------------------- MMAR_0099|M.marinum_M PIIGIQQVPSDQEVEP---------------------------------- Mb0104|M.bovis_AF2122/97 SPELRTVLLTGATGFLG--------------------------------- Rv0101|M.tuberculosis_H37Rv SPELRTVLLTGATGFLG--------------------------------- Mflv_2697|M.gilvum_PYR-GCK QIRALLQSVVDAHPVLRTRLDR-----AAMTLVDGGFDLPLTEIEV---- Mvan_3844|M.vanbaalenii_PYR-1 RLEQILQALLDRHDMLRAILDERG---RLVTRPPGAVRVADVLRVV---- MUL_3633|M.ulcerans_Agy99 SIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIRLPE MLBr_02353|M.leprae_Br4923 DIRAVLTAVVNHHDVLRLSLVDND----GMWEQHIAATGEFTRLLTQTLP . MAB_4099c|M.abscessus_ATCC_199 VGTVDARACLLAVEALSDEALRHARSRLNPATGSMLSALWESGKNRLVLI MAV_3244|M.avium_104 AGSVQAADCLETVDALSPAALVDARSRLNLADGILVRAVWASETSQLALI TH_3730|M.thermoresistible__bu SGAVTARGCLRTVHRLSGDELRSARAELDPAAGTMVRALWAPDTRRLALI MSMEG_0402|M.smegmatis_MC2_155 -GRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDP---LLR MMAR_0099|M.marinum_M ----------GSVGDMARRYVDMIQAHHPDGPYNLLGWSMGG------VV Mb0104|M.bovis_AF2122/97 ---RYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDP--ELL Rv0101|M.tuberculosis_H37Rv ---RYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDP--ELL Mflv_2697|M.gilvum_PYR-GCK --GDEGSAAVARHAAAALEHLDPQRGPLWGAVWLRGSDDADSTSSVLLLT Mvan_3844|M.vanbaalenii_PYR-1 --DAAAHTVLAAEVVAALDRIDPTSGAMVQAVWFRHG------PPVLALC MUL_3633|M.ulcerans_Agy99 GSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANMLLLT MLBr_02353|M.leprae_Br4923 DGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAHGGPHYLGLA : . : MAB_4099c|M.abscessus_ATCC_199 VHHLAVDAVSWRILLEDFNIAWAQHHGGQAVELPSGGTSFARWATLLDER MAV_3244|M.avium_104 IHHLAVDGVSWRTLIEDLNIAWAQHHSGQPVALPTGGMSFARWSALLEDH TH_3730|M.thermoresistible__bu VHHLAVDAVSWRILVEDINIAWGQRHTGQPIDLPAGGTSFARWSTLLAEY MSMEG_0402|M.smegmatis_MC2_155 KHFNELATERLQVVAGDK---------GQ----PNLGLDEQTWQRLAESV MMAR_0099|M.marinum_M AHEIAVELRRR--------------------GCEVGRLIVLDAAGEVDSA Mb0104|M.bovis_AF2122/97 RHFKELAADRLEVVAGDK-------------SEPDLGLDQPMWRRLAETV Rv0101|M.tuberculosis_H37Rv RHFKELAADRLEVVAGDK-------------SEPDLGLDQPMWRRLAETV Mflv_2697|M.gilvum_PYR-GCK AHVLAMDPVSWQIVIGELDAGWHALAGGRAPAALGEHTGYRQWSNLLRER Mvan_3844|M.vanbaalenii_PYR-1 VHHLSTDVVSWYLILGALAQIDATLAAGHAPDPAAEYTTYREWTRRLYQR MUL_3633|M.ulcerans_Agy99 AHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHR MLBr_02353|M.leprae_Br4923 VHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAAL * MAB_4099c|M.abscessus_ATCC_199 ARTADVEALTDTWRQVEKIPPALPAVHPTMDTYASAGQLSVSLDADLTRE MAV_3244|M.avium_104 ARRPEVVERAEDWRQVAAVPAVLPGAQP-GDTYATAGQLSASLDVETTRL TH_3730|M.thermoresistible__bu ADTPEVVAQAGVWQQVAAX------XWPSCSTPTTTSSSTSTWRSTRS-- MSMEG_0402|M.smegmatis_MC2_155 DLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTS-- MMAR_0099|M.marinum_M DSVAEPASESDVLELILVAAGIDIAEHPRPLTYHEAEALLN--------- Mb0104|M.bovis_AF2122/97 DLIVDSAAMVNAFP-YHELFGPNVAGTAELIRIALTTKLKPFTYVSTADV Rv0101|M.tuberculosis_H37Rv DLIVDSAAMVNAFP-YHELFGPNVAGTAELIRIALTTKLKPFTYVSTADV Mflv_2697|M.gilvum_PYR-GCK AESSDG---LQFWLDQLGGPDPALGARRVRPDTDRAGDVRVTVTVTGADV Mvan_3844|M.vanbaalenii_PYR-1 SRTEAVERRRGFWVEQLAGSDPLLGRRLPDPRHDTWSTLQSTDVVTDAGA MUL_3633|M.ulcerans_Agy99 ASAPQVQDQRDYWAALVREPDPELGLRYPDPTRDTWSTLQLTRAAIPVDV MLBr_02353|M.leprae_Br4923 ATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCT-- MAB_4099c|M.abscessus_ATCC_199 LLGEVPVAYHAGVQDILLIAFALAWNEFLGSAGAPIGIDVEGHGRNEEFV MAV_3244|M.avium_104 LLGEVPAAFHAGVQDILLIAFGLAWTQFIG-TGAPIGIDVEGHGRSEELG TH_3730|M.thermoresistible__bu -------------------------------TGRPVRTGCS--------- MSMEG_0402|M.smegmatis_MC2_155 ---------------------------DVGRQIEPSRFTEQADIRLVSAT MMAR_0099|M.marinum_M -------------------------------QRTPVEFSLPPRRIVEIML Mb0104|M.bovis_AF2122/97 G-----------------------------AAIEPSAFTEDADIRVISPT Rv0101|M.tuberculosis_H37Rv G-----------------------------AAIEPSAFTEDADIRVISPT Mflv_2697|M.gilvum_PYR-GCK T--------------------------------ARLLAGP---HPVLDVL Mvan_3844|M.vanbaalenii_PYR-1 TR----------------------------AILDRLDGAS---LEVRDFL MUL_3633|M.ulcerans_Agy99 T--------------------------------ERVLGAVRRDQGVRELL MLBr_02353|M.leprae_Br4923 ---------------------------------LSVEQTSELDDARRRFR MAB_4099c|M.abscessus_ATCC_199 ADADLSRTVGWFT---SKYPVSLAVGELSWAQVVAGDPALGPVIKGAKEQ MAV_3244|M.avium_104 PQVDLSRTVGWFT---AKYPVALRLGGLSWGQVVGGDEALGAVVKEAKEQ TH_3730|M.thermoresistible__bu TRCSSTRTIRSMR---RRWP---------------GRKALRSPISRAANT MSMEG_0402|M.smegmatis_MC2_155 RKIEVGYANGYGN---SKWA---------------GEVLLREAHDHCGLP MMAR_0099|M.marinum_M DNMNANQSMRLKH---VPDVFD-------------GDMIVFSAKRDSGGR Mb0104|M.bovis_AF2122/97 RTVDGGWAGGYGT---SKWA---------------GEVLLREANDLCALP Rv0101|M.tuberculosis_H37Rv RTVDGGWAGGYGT---SKWA---------------GEVLLREANDLCALP Mflv_2697|M.gilvum_PYR-GCK VAALGRTITEWRGRRNQ-------------------PTPP-PLVALETHG Mvan_3844|M.vanbaalenii_PYR-1 LTALTLTLASWRIERGQ-------------------PAHHGALVALEGHG MUL_3633|M.ulcerans_Agy99 LAATAMAVASWRRVRAQ-------------------DPAAGVLVALEGHG MLBr_02353|M.leprae_Br4923 RSIQAIVLAALGR--------------------TIAQTVGDGVVAVELEG MAB_4099c|M.abscessus_ATCC_199 LRTLPDGLTYGLLRYLNPDADVAGPDPSIGFNYLGRLGAGGVDLSDDLWR MAV_3244|M.avium_104 LRALPDGLTYGLLRYLNPQAGLDVSDPAIAFNYLGRLGGGAAELSPELWR TH_3730|M.thermoresistible__bu T------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 VAVFRSG------------------------------------------- MMAR_0099|M.marinum_M S------------------------------------------------- Mb0104|M.bovis_AF2122/97 VAVFRCG------------------------------------------- Rv0101|M.tuberculosis_H37Rv VAVFRCG------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK RAALAEA------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 R------------------------------------------------- MUL_3633|M.ulcerans_Agy99 R------------------------------------------------- MLBr_02353|M.leprae_Br4923 E------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 IDQDGVAITAAATAVPTPLGHTVELNAGVMEDADAGARLHATWTWALSAL MAV_3244|M.avium_104 LSPDSFALAGAAGAVELPLPHTVELNAGTMDTEDG-PHLQANWTWARSAL TH_3730|M.thermoresistible__bu -------------------------------------TIRCRWSQCPGTS MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------MIMVDPTYAGQLN MMAR_0099|M.marinum_M -------------------------------------LADSWRQYVAGDI Mb0104|M.bovis_AF2122/97 -------------------------------------MILADTSYAGQLN Rv0101|M.tuberculosis_H37Rv -------------------------------------MILADTSYAGQLN Mflv_2697|M.gilvum_PYR-GCK ----------------------------------------DTADTADTAD Mvan_3844|M.vanbaalenii_PYR-1 ----------------------------------------EDALVGGGVD MUL_3633|M.ulcerans_Agy99 ------------------------------------------ADAVLDTD MLBr_02353|M.leprae_Br4923 ----------------------------------------GRSVLRPDVD MAB_4099c|M.abscessus_ATCC_199 SHNQVDRISRLWFDSLAGICAHVRGGGGGLSPSDVMPARLTQQQIDQLDE MAV_3244|M.avium_104 DDKQIGRLSELWFDALAGICTHVRAGGGGLTPSDVAAARLTQRDLDELAQ TH_3730|M.thermoresistible__bu SDCASNTTPRCSTPRMS---RHWSAGCGGC-------------------- MSMEG_0402|M.smegmatis_MC2_155 VTDTVSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDG------------ MMAR_0099|M.marinum_M TEYPIDCTHEAMLNIES---LQLFADRIAIYLR----------------- Mb0104|M.bovis_AF2122/97 MSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDG------------ Rv0101|M.tuberculosis_H37Rv MSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDG------------ Mflv_2697|M.gilvum_PYR-GCK TSDTVGLLSAIYPLRLHE-------DSPG--------------------- Mvan_3844|M.vanbaalenii_PYR-1 TSATVGWFTSVYPVRLGAGEAAIDVDTAARNPA----------------- MUL_3633|M.ulcerans_Agy99 TTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPV----------------- MLBr_02353|M.leprae_Br4923 VRRTIGWFTNYYPIPLVCVKGQGALAQLDAVHN----------------- MAB_4099c|M.abscessus_ATCC_199 QYEIADVLPLTPLQQGLLFHSNLAPEGLEGSDDLYAVQLDVALSGPLDPK MAV_3244|M.avium_104 RYRVADVLPLTPLQQGLLFHAGTAQGSQE-PEDLYAVQLDISVTGAVDPD TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 --LPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYI MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 ------LPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYV Rv0101|M.tuberculosis_H37Rv ------LPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYV Mflv_2697|M.gilvum_PYR-GCK -------------ATTELIAGVPAGGIDYGLLRYLRPDTSEVLKAHPEPQ Mvan_3844|M.vanbaalenii_PYR-1 ------AARSLLRAVIQQLAEVPDKGLDYGLLRYTRRD--ETLRALPEPQ MUL_3633|M.ulcerans_Agy99 ------AAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGV--AELVDAVDPQ MLBr_02353|M.leprae_Br4923 -----------------TLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPD MAB_4099c|M.abscessus_ATCC_199 RLQDAVHSAIRRRPNVVARFYEEFGEPVQLIPADPELAWQYLELDADSEA MAV_3244|M.avium_104 RLREAVRTVITRHPNVVAHFSEDFGEPVQILSAEPELAWQYVELDAGADL TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 DWLIEAGYPIER--------IEDFGEWLQRFEAA-------LQGLSDQQR MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 DWLIEAGYPIRR--------IDDFAEWLQRFEAS---------LGALPDR Rv0101|M.tuberculosis_H37Rv DWLIEAGYPIRR--------IDDFAEWLQRFEAS---------LGALPDR Mflv_2697|M.gilvum_PYR-GCK ILLNYLG----------------------RTDLVPSG-----AIVADRLL Mvan_3844|M.vanbaalenii_PYR-1 VEFNYIG----------------------RYDLSADQTSQAWSLITDETL MUL_3633|M.ulcerans_Agy99 IQFSYLG----------------------RLDLGGVADQP-WSLLTGPYL MLBr_02353|M.leprae_Br4923 IHFRYVGVVPEP---------PSVDATVQFDSDMTIPVQEPVPGMGHAIE MAB_4099c|M.abscessus_ATCC_199 EEQVERLAASERAAVCDLAGQPAFRAALARTGTDQYRFLVTNHHIVLDG- MAV_3244|M.avium_104 DEQVERLSSAERVAVGDLA-QPPFRGALIRTAEDAYRFVLTNHHIVLDG- TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 QNSVLQMLTLLKQQAGELQPPVPTRGSFAP--ADRFQAAVRDANIGVEG- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 QRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNP Rv0101|M.tuberculosis_H37Rv QRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNP Mflv_2697|M.gilvum_PYR-GCK LSGLSTVPEPNAAVRHELTVVAAVVAHGDEPALVAQWRVLPEILSDTDVE Mvan_3844|M.vanbaalenii_PYR-1 NAHMPAAAEPDLPLRYTFDVISVISGGADGPQLRTSWRWSTALSTSTEVD MUL_3633|M.ulcerans_Agy99 DA-LPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAVFERSDID MLBr_02353|M.leprae_Br4923 LRTYRFGGSLHLDWWYDIRRIPQVTAEALAQSFPVTLSKLIQEGIATQKD MAB_4099c|M.abscessus_ATCC_199 WSKPILLQEIFASYFGERLPAPVAYRRFVTWLSGQDNDAARSAWGKVFEG MAV_3244|M.avium_104 WSKPLLLQEIFAAYFGVRLPAPVPYRNFITWLSAQDRAAAQAAWREVLAG TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 EIPHVTREVIVKYVTDLQLLGLL--------------------------- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 DIPHVSAPTIINYVTNLQLLGLL--------------------------- Rv0101|M.tuberculosis_H37Rv DIPHVSAPTIINYVTNLQLLGLL--------------------------- Mflv_2697|M.gilvum_PYR-GCK EMQTIWQD---TLREVL--------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 RLTALWQQAVTVLGEAL--------------------------------- MUL_3633|M.ulcerans_Agy99 HLTGLWQRGIAALAAGLD-------------------------------- MLBr_02353|M.leprae_Br4923 AHDESEMAGAPQAGVLVDLSTLDAG------------------------- MAB_4099c|M.abscessus_ATCC_199 FETPTLVGPPGRMVLGRRGVESFEVSAETTQALGELARSCRTTVSTVLQA MAV_3244|M.avium_104 FDTPTLVGPSGRMALGPRGVAEFHVPADTSRLLGELARSCRTTVSTVLQA TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 AWAQLLMWLTGQTDVAFGTAVSGRPTDLVGAESMVGLLINTVPVRATITP MAV_3244|M.avium_104 AWAQLLMWLTGQHDVVFGTAVSGRPTELAGSESMVGLLINTVPVRATIGA TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 DTTIASLLNQLQAAYGETLEHQHLALKEIHHAVGHDQLFDTMFVYENYPI MAV_3244|M.avium_104 ETTIADLLDQLQRAYTHTLEHQHLALNDIHRVTGHDQIFDTMFVYENYPI TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 DTAALSRVHELSITGFSNREYNHYPLAVQATPGHELGLRVEFDTDVFNAV MAV_3244|M.avium_104 DTAALSAVDELTITGFTNREYNHYPLSVQAVPGHEIGLRVEFDTDVFGEA TH_3730|M.thermoresistible__bu -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0099|M.marinum_M -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MAB_4099c|M.abscessus_ATCC_199 RIGKLVKRFQRVLEAMTSDVKGKKKEPT MAV_3244|M.avium_104 RIEKLIERFRRVLEAMTVDLEEQS---- TH_3730|M.thermoresistible__bu ---------------------------- MSMEG_0402|M.smegmatis_MC2_155 ---------------------------- MMAR_0099|M.marinum_M ---------------------------- Mb0104|M.bovis_AF2122/97 ---------------------------- Rv0101|M.tuberculosis_H37Rv ---------------------------- Mflv_2697|M.gilvum_PYR-GCK ---------------------------- Mvan_3844|M.vanbaalenii_PYR-1 ---------------------------- MUL_3633|M.ulcerans_Agy99 ---------------------------- MLBr_02353|M.leprae_Br4923 ----------------------------