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M. thermoresistible (build 8) TH_1770 (echA13)

annotation: POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
coordinates: 3455683 - 3456591
length: 303

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1770echA13-100% (303)POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8)TH_2027echA13e-10962.07% (290) POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE)
M. thermoresistible (build 8)TH_1273-2e-8865.97% (238) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1970cechA131e-10964.41% (295) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_1568-1e-10059.73% (298) enoyl-CoA hydratase
M. tuberculosis H37RvRv1935cechA131e-10964.41% (295) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-4e-1626.87% (227) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_2058-3e-2031.39% (223) enoyl-CoA dehydratase/isomerase
M. marinum MMMAR_2863echA131e-11165.19% (293) enoyl-CoA hydratase EchA13
M. avium 104MAV_0670-1e-10361.77% (293) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5886-3e-9862.01% (279) enoyl-CoA hydratase
M. ulcerans Agy99MUL_1414echA21e-1629.54% (237) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_5190-1e-10262.41% (290) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1970c|M.bovis_AF2122/97           MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
Rv1935c|M.tuberculosis_H37Rv        MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_2863|M.marinum_M               MNVAGVSPVDRRSNGERAAP--DFTYVRYETIDDGRIATITLNRPKQRNA
TH_1770|M.thermoresistible__bu      -----------MS---------DYKFLMWESHDDGTIVRILLNRPEARNA
Mflv_1568|M.gilvum_PYR-GCK          -----MQRVADQD------------QVTYETLDEGRIARIWLNRPDAQNA
Mvan_5190|M.vanbaalenii_PYR-1       -----MQRVATLE------------QVTYETLDEGRIARIWLNRPDAQNA
MSMEG_5886|M.smegmatis_MC2_155      -MPYLLMRWFDMTGSDGDGG--QARQIEYETLDEGRIARIWLNRPQAQNA
MAV_0670|M.avium_104                -----MTLSEQAGAQPGARP--AEELVTYETLDEGRIARIWLNRPDAHNA
MAB_2058|M.abscessus_ATCC_1997      ---------------------MAEQPIRYEVVDS--VAWLTINRPEARNA
MLBr_02402|M.leprae_Br4923          -----------------------MKYDTILVDGYQRVGIITLNRPQALNA
MUL_1414|M.ulcerans_Agy99           --------------------MPTPEFQTLLYSTAGPVATITLNRPEHLNT
                                                                        :  : ::**.  *:

Mb1970c|M.bovis_AF2122/97           QTRGMLVELGAAFELAEADDTVRVVILRAAG-PAFSAGHDLGSADDIRER
Rv1935c|M.tuberculosis_H37Rv        QTRGMLVELGAAFELAEADDTVRVVILRAAG-PAFSAGHDLGSADDIRER
MMAR_2863|M.marinum_M               QTRGMLVELGAAFELAEADDTVRVVILRGEG-PAFSAGHDLGSADDVRER
TH_1770|M.thermoresistible__bu      QNRGMLVELDDAFGRAEADDKVRVVILAGEG-KMFSSGHDIGSAVAKAEY
Mflv_1568|M.gilvum_PYR-GCK          QSRTLLVQLDEAFGRAEADDVVRVVILAARG-KNFSAGHDLGSEAALAER
Mvan_5190|M.vanbaalenii_PYR-1       QSRTLLVQLDEAFGRAEADDEVRVVILAARG-KNFSAGHDLGSEEAIAER
MSMEG_5886|M.smegmatis_MC2_155      QSRTLLVQLDEAFARAEADDTVRVVILAARG-KNFSAGHDLGSEEALAER
MAV_0670|M.avium_104                QSRGLLVQLDEAFVRAEADDAVRVVILAARG-KNFSAGHDLGSELALAER
MAB_2058|M.abscessus_ATCC_1997      LNNAVRTGLIDAVLRFNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQNALK
MLBr_02402|M.leprae_Br4923          LNSQMMNEITNAAKELDIDPDVGAILITGSP-KVFAAGADIKEMASLTFT
MUL_1414|M.ulcerans_Agy99           IVPPMPDEIEAAVGLAERDQGIKVIVLRGAG-RAFSGGYDFGGGFQHWGE
                                        :   :  *    : *    .::: .     *..* *:         

Mb1970c|M.bovis_AF2122/97           SPGPDQHPSYRCNGATFGGVESRN-RQEWHYYFENTKRWRNLRKITIAQV
Rv1935c|M.tuberculosis_H37Rv        SPGPDQHPSYRCNGATFGGVESRN-RQEWHYYFENTKRWRNLRKITIAQV
MMAR_2863|M.marinum_M               APGPDQHPTYQCNGGTYGGVESRN-RQEWHYYFENTKRWRNLRKITVAQV
TH_1770|M.thermoresistible__bu      RPGPDQHPTMKITGGTRDGAESRM-LQEWHYFFQNTLRWRNLRKITIAQV
Mflv_1568|M.gilvum_PYR-GCK          APGPDQHPTFTCNGATREAVIERTYLQEWHYFFNNTSRWRDLRKITIAQV
Mvan_5190|M.vanbaalenii_PYR-1       TPGPDQHPTFTFNGGTRDAISERTYLQEWHYFFNNTSRWRDLRKITIAQV
MSMEG_5886|M.smegmatis_MC2_155      EPGPGQHPTFAGYGATVAGVAERTYRQEWHFYFENTKRWRDLRKITIAQV
MAV_0670|M.avium_104                QPGPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQV
MAB_2058|M.abscessus_ATCC_1997      VPPKDFAPQFGRN--------------------------IDVAKPTIAAV
MLBr_02402|M.leprae_Br4923          DAFDAD-------------------------FFSAWGKLAAVRTPMIAAV
MUL_1414|M.ulcerans_Agy99           TMMTDGQWDPGKDFAMVTARETAP--------TQKFMAIWRASKPVIAQI
                                                                               .  :* :

Mb1970c|M.bovis_AF2122/97           HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGV-EYFGHPWEFG
Rv1935c|M.tuberculosis_H37Rv        HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGV-EYFGHPWEFG
MMAR_2863|M.marinum_M               HGTVLSAGLMLAWCCDLIVAADDTVFADVVGTRLGMCGV-EYFGHPWEFG
TH_1770|M.thermoresistible__bu      HGDVFSAGLMLMWACDLIVGSEEVRFADVVGTRLGMCGM-EYFGHPWEFG
Mflv_1568|M.gilvum_PYR-GCK          QGNAISAALMLIWACDLIVASDDAKFSDVVAVRMGMPGV-EYYAHPWEFG
Mvan_5190|M.vanbaalenii_PYR-1       QGNAISAGLMLIWACDLIVASDDARFSDVVAVRMGMPGV-EYYAHPWEFG
MSMEG_5886|M.smegmatis_MC2_155      QGNAISAALMLIWACDLIVAADDARFSDVVAVRMGMPGV-EYYAHPWEFG
MAV_0670|M.avium_104                QGNAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPGV-EYYAHPWEFG
MAB_2058|M.abscessus_ATCC_1997      NGVAFAGGFLLAQQCDLVVAAEHATFA-VSEVKVGRGSP-WATPLSWLVP
MLBr_02402|M.leprae_Br4923          AGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIG
MUL_1414|M.ulcerans_Agy99           HGWCVGGASDYALCADIVIASDDAVIGTPYSRMWGAYLS---GMWLYRLS
                                     *  ....      .*:::.:: . :.                     . 

Mb1970c|M.bovis_AF2122/97           PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
Rv1935c|M.tuberculosis_H37Rv        PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
MMAR_2863|M.marinum_M               PRKAKELLLTGDSIGADEAHALGMVSKVFPGEDLADSAIEFARRIAKLPT
TH_1770|M.thermoresistible__bu      PRKTKELMLTGDAIDIHEAYQLGMVSKVFKREELAERTLEMARRIAQVPT
Mflv_1568|M.gilvum_PYR-GCK          ARKAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFARRIAERPT
Mvan_5190|M.vanbaalenii_PYR-1       ARKAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFARRIAERPT
MSMEG_5886|M.smegmatis_MC2_155      PRKAKELLLTGDSIDADEAYRLGMVSKVFGREELEDKTLEFARRIAERPT
MAV_0670|M.avium_104                PRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAERPT
MAB_2058|M.abscessus_ATCC_1997      PRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRERTQQLALSIAANAP
MLBr_02402|M.leprae_Br4923          KAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSR
MUL_1414|M.ulcerans_Agy99           FAKAKWHSLTGRPLSGVQAAQIELINEAVPFERLEARVAEVAAELAQIPL
                                       :    ***  :   .*    ::....    *   .  .*  ::  . 

Mb1970c|M.bovis_AF2122/97           MAALLIKESVNQTVDAMGFSAALDGC-----FKIHQLNHAHWGEVTGGKL
Rv1935c|M.tuberculosis_H37Rv        MAALLIKESVNQTVDAMGFSAALDGC-----FKIHQLNHAHWGEVTGGKL
MMAR_2863|M.marinum_M               MAALLIKESVNQTVDAMGFTTALDGC-----FKIHQLNHAHWAEVTGGKL
TH_1770|M.thermoresistible__bu      MAALLIKESVNQTMDNMGFYNSLQAC-----FSLHQLNHSHWAEVREDKV
Mflv_1568|M.gilvum_PYR-GCK          MAALLVKDSVNAASDAMGFTEALRHA-----FHIHELGHAHWAAYNENRY
Mvan_5190|M.vanbaalenii_PYR-1       MAALLVKDSVNAASDAMGFTEALRHA-----FHIHELGHAHWAAYNENRY
MSMEG_5886|M.smegmatis_MC2_155      MAALLVKDSVNAAADSMGFAEALHHA-----FHIHELGHAHWAAANENRW
MAV_0670|M.avium_104                MAALLIKDSVNAASDAMGFTEALRHA-----FHIHELGHAHWAAHNENRY
MAB_2058|M.abscessus_ATCC_1997      LSVLASKRTVYLSAQHH-LAAAYDLA-----DEIWEP---VYLSDDAQEG
MLBr_02402|M.leprae_Br4923          SATRMAKEAVNRSFEST----LAEGL-----LHERRLFHSTFVTDDQSEG
MUL_1414|M.ulcerans_Agy99           SQLQAQKLIVNQAYENMGLASTQTLGGILDGLMRNTPDALDFIKTAENQG
                                          *  *  : :                          :      . 

Mb1970c|M.bovis_AF2122/97           SYGTVEYGLEDWRAAPQIRPAIKQRP----------
Rv1935c|M.tuberculosis_H37Rv        SYGTVEYGLEDWRAAPQIRPAIKQRP----------
MMAR_2863|M.marinum_M               CYGTVEYGLDDWRAAPEILPATKRRP----------
TH_1770|M.thermoresistible__bu      PRAGEEHGVPNWRTAPPIVVSVKDKVRADG------
Mflv_1568|M.gilvum_PYR-GCK          PVG-LPPNVPDWRTLGAPKLSRRDEP----------
Mvan_5190|M.vanbaalenii_PYR-1       PVG-LPPNVPDWRTLGAPKLSRRDQP----------
MSMEG_5886|M.smegmatis_MC2_155      PVG-MPPDVPDWRTLGAPKLARRDTP----------
MAV_0670|M.avium_104                PVG-LPPDVEDWRNAKPTRLARRDTP----------
MAB_2058|M.abscessus_ATCC_1997      PAAFREKRAPQWKGH---------------------
MLBr_02402|M.leprae_Br4923          MAAFIEKRAPQFTHR---------------------
MUL_1414|M.ulcerans_Agy99           VRAAVERRDGPFGDYSQAPPELRPNPNHVIVPDRDR
                                      .        :