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MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNAQTRGMLVELGAAFELAEADD TVRVVILRAAGPAFSAGHDLGSADDIRERSPGPDQHPSYRCNGATFGGVESRNRQEWHYYFENTKRWRNL RKITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFGHPWEFGPRKTKELLLTGDC IGADEAHALGMVSKVFPADELATSTIEFARRIAKVPTMAALLIKESVNQTVDAMGFSAALDGCFKIHQLN HAHWGEVTGGKLSYGTVEYGLEDWRAAPQIRPAIKQRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1970c | echA13 | - | 100% (318) | enoyl-CoA hydratase |
| M. bovis AF2122 / 97 | Mb0464c | echA2 | 2e-19 | 30.52% (249) | enoyl-CoA hydratase |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 1e-18 | 29.05% (241) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1568 | - | 2e-97 | 60.68% (295) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1935c | echA13 | 0.0 | 100.00% (318) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 5e-15 | 27.57% (243) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0834 | - | 2e-23 | 33.20% (250) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2863 | echA13 | 1e-164 | 86.16% (318) | enoyl-CoA hydratase EchA13 |
| M. avium 104 | MAV_0670 | - | 1e-101 | 60.13% (311) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5886 | - | 8e-98 | 60.33% (300) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2027 | echA13 | 1e-109 | 63.27% (294) | POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 1e-19 | 30.71% (241) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4005 | - | 1e-142 | 78.64% (295) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1568|M.gilvum_PYR-GCK -----MQRVADQD------------QVTYETLDEGRIARIWLNRPDAQNA
MSMEG_5886|M.smegmatis_MC2_155 -MPYLLMRWFDMTGSDGDGG--QARQIEYETLDEGRIARIWLNRPQAQNA
MAV_0670|M.avium_104 -----MTLSEQAGAQPGARP--AEELVTYETLDEGRIARIWLNRPDAHNA
Mb1970c|M.bovis_AF2122/97 MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
Rv1935c|M.tuberculosis_H37Rv MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_2863|M.marinum_M MNVAGVSPVDRRSNGERAAP--DFTYVRYETIDDGRIATITLNRPKQRNA
Mvan_4005|M.vanbaalenii_PYR-1 -----MQDFDT-----------LFTYLRYELVEQGRVAVITLDRPKQRNA
TH_2027|M.thermoresistible__bu -----MQMTERTG--------AEYSYVTYEVLDEGRIARIMMNRPRQRNA
MLBr_02402|M.leprae_Br4923 -----------------------MKYDTILVDGYQRVGIITLNRPQALNA
MUL_0210|M.ulcerans_Agy99 -----------------------MSYETILVERDQRVGIITLNRPQALNA
MAB_0834|M.abscessus_ATCC_1997 --------------------------MIRVEPREHGILVVTIDRPERRNA
: : ::** **
Mflv_1568|M.gilvum_PYR-GCK QSRTLLVQLDEAFGRAEADDVVRVVILAARGKNFSAGHDLGSEAALAERA
MSMEG_5886|M.smegmatis_MC2_155 QSRTLLVQLDEAFARAEADDTVRVVILAARGKNFSAGHDLGSEEALAERE
MAV_0670|M.avium_104 QSRGLLVQLDEAFVRAEADDAVRVVILAARGKNFSAGHDLGSELALAERQ
Mb1970c|M.bovis_AF2122/97 QTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERS
Rv1935c|M.tuberculosis_H37Rv QTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERS
MMAR_2863|M.marinum_M QTRGMLVELGAAFELAEADDTVRVVILRGEGPAFSAGHDLGSADDVRERA
Mvan_4005|M.vanbaalenii_PYR-1 QNRGILVELGSAFELAEADDTVRVVILRGAGPSFSAGHDLGSSDDVRERA
TH_2027|M.thermoresistible__bu QNRGLLVELDDAFMRAERDDDVRVVILGGIGPMFSSGHDLGSSDDRAERS
MLBr_02402|M.leprae_Br4923 LNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMAS-----
MUL_0210|M.ulcerans_Agy99 LNSQVMNEVTSAAAELDNDPGIGAIIITGSAKAFAAGADIKEMAD-----
MAB_0834|M.abscessus_ATCC_1997 LDPQTVAELHAVIESIDGDPKVRVVVLTAVGASFCAGADLKSLPSDFTSA
: :: . : * : .::: . *.:* *: .
Mflv_1568|M.gilvum_PYR-GCK PGPDQHPTFTCNGATREAVIERTYLQEWHYFFNNTSRWRDLRKITIAQVQ
MSMEG_5886|M.smegmatis_MC2_155 PGPGQHPTFAGYGATVAGVAERTYRQEWHFYFENTKRWRDLRKITIAQVQ
MAV_0670|M.avium_104 PGPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQVQ
Mb1970c|M.bovis_AF2122/97 PGPDQHPSYRCNGATFGGVESR-NRQEWHYYFENTKRWRNLRKITIAQVH
Rv1935c|M.tuberculosis_H37Rv PGPDQHPSYRCNGATFGGVESR-NRQEWHYYFENTKRWRNLRKITIAQVH
MMAR_2863|M.marinum_M PGPDQHPTYQCNGGTYGGVESR-NRQEWHYYFENTKRWRNLRKITVAQVH
Mvan_4005|M.vanbaalenii_PYR-1 PGPGQHPTYQCNGGTLGGVESR-HRQEWHYFFENTRRWRNLRKITIAEVH
TH_2027|M.thermoresistible__bu GGPAGHPTYLFNGGSRQGTEQR-MLQEWHYYFENARRWRNLKKITIAETH
MLBr_02402|M.leprae_Br4923 --------------------LTFTDAFDADFFSAWGKLAAVRTPMIAAVA
MUL_0210|M.ulcerans_Agy99 --------------------LTFSEAFDADFFAAWGKLAAVRTPTIAAVA
MAB_0834|M.abscessus_ATCC_1997 GVTSTAALLAATDS-----ELVRTLAAQELMASLFERIHRMRQPVIAAVN
: :: :* .
Mflv_1568|M.gilvum_PYR-GCK GNAISAALMLIWACDLIVASDDAKFSDVVAVRMGMPG--VEYYAHPWEFG
MSMEG_5886|M.smegmatis_MC2_155 GNAISAALMLIWACDLIVAADDARFSDVVAVRMGMPG--VEYYAHPWEFG
MAV_0670|M.avium_104 GNAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPG--VEYYAHPWEFG
Mb1970c|M.bovis_AF2122/97 GAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCG--VEYFGHPWEFG
Rv1935c|M.tuberculosis_H37Rv GAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCG--VEYFGHPWEFG
MMAR_2863|M.marinum_M GTVLSAGLMLAWCCDLIVAADDTVFADVVGTRLGMCG--VEYFGHPWEFG
Mvan_4005|M.vanbaalenii_PYR-1 GMVLSAGLMLAWCCDLIVAAEDTVFADVVGTRLGMCG--VEFFGHPWEFG
TH_2027|M.thermoresistible__bu GPVLAAGLMIAWTCDLIVATPTTTFADVVGTRIGMCG--VEYFAHPWELG
MLBr_02402|M.leprae_Br4923 GYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPG-MGGSQRLTRAIG
MUL_0210|M.ulcerans_Agy99 GYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPG-MGGSQRLTRAIG
MAB_0834|M.abscessus_ATCC_1997 GHAIGGGFALALACDIRFASPAASFGAVFIRHGVSNCDMGTSYHLPRLVG
* .:... : **: .*: : *. . .*
Mflv_1568|M.gilvum_PYR-GCK ARKAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFARRIAERPT
MSMEG_5886|M.smegmatis_MC2_155 PRKAKELLLTGDSIDADEAYRLGMVSKVFGREELEDKTLEFARRIAERPT
MAV_0670|M.avium_104 PRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAERPT
Mb1970c|M.bovis_AF2122/97 PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
Rv1935c|M.tuberculosis_H37Rv PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
MMAR_2863|M.marinum_M PRKAKELLLTGDSIGADEAHALGMVSKVFPGEDLADSAIEFARRIAKLPT
Mvan_4005|M.vanbaalenii_PYR-1 PRKAKELLLTGDALGADDAHAIGMVSKVFGNDELSDRAVEFAGRIAKLPT
TH_2027|M.thermoresistible__bu PRRAKELLLTGDSLDAHTAHQWGMVSRIFPDDELQKRTMELAQRIAGLPT
MLBr_02402|M.leprae_Br4923 KAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSR
MUL_0210|M.ulcerans_Agy99 KAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVATTISQMSR
MAB_0834|M.abscessus_ATCC_1997 AARAAELMLTGRVFDAQEAYRMGLVFDVVPAEELLDAALSKAREIAVHSP
:: :*:*** :.* * *:* :. :* : * *: .
Mflv_1568|M.gilvum_PYR-GCK MAALLVKDSVNAASDAMGFTEALRHAFHIHELGHAHWAAYNENRYPVGLP
MSMEG_5886|M.smegmatis_MC2_155 MAALLVKDSVNAAADSMGFAEALHHAFHIHELGHAHWAAANENRWPVGMP
MAV_0670|M.avium_104 MAALLIKDSVNAASDAMGFTEALRHAFHIHELGHAHWAAHNENRYPVGLP
Mb1970c|M.bovis_AF2122/97 MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
Rv1935c|M.tuberculosis_H37Rv MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
MMAR_2863|M.marinum_M MAALLIKESVNQTVDAMGFTTALDGCFKIHQLNHAHWAEVTGGKLCYGTV
Mvan_4005|M.vanbaalenii_PYR-1 ATALFIKESVNQSVDAMGFSSALDACFSIHQLNHAYWAEITGNPLGIGTV
TH_2027|M.thermoresistible__bu VTALLIKEAVNQSVDNMGFYNALNACFSLHQINHAHWAEVTGGESHLGTP
MLBr_02402|M.leprae_Br4923 SATRMAKEAVNRSFES-TLAEGLLHERRLFHSTFVTDDQSEG--------
MUL_0210|M.ulcerans_Agy99 SAARMAKEAVNRTFEA-TLAEGLLYERRLIHSAFATADQSEG--------
MAB_0834|M.abscessus_ATCC_1997 LAVWMTKETMWQTVDAPSLRHALDLENRTQVMCTATGELRRS--------
:. : *::: : : : .* .
Mflv_1568|M.gilvum_PYR-GCK PN-VPDWRTLGAPKLSRRDEP
MSMEG_5886|M.smegmatis_MC2_155 PD-VPDWRTLGAPKLARRDTP
MAV_0670|M.avium_104 PD-VEDWRNAKPTRLARRDTP
Mb1970c|M.bovis_AF2122/97 EYGLEDWRAAPQIRPAIKQRP
Rv1935c|M.tuberculosis_H37Rv EYGLEDWRAAPQIRPAIKQRP
MMAR_2863|M.marinum_M EYGLDDWRAAPEILPATKRRP
Mvan_4005|M.vanbaalenii_PYR-1 EDGLEDWQIAPEILPATKNRP
TH_2027|M.thermoresistible__bu EFGVPRWQDAGPILPRPMSEA
MLBr_02402|M.leprae_Br4923 ---MAAFIEKRAPQFTHR---
MUL_0210|M.ulcerans_Agy99 ---MAAFIEKRPPNFTHR---
MAB_0834|M.abscessus_ATCC_1997 ---FDAFREGRG---------
. :