For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2027 (echA13)

annotation: POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
coordinates: 3980690 - 3981607
length: 306

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2027echA13-100% (306)POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8)TH_1770echA13e-10962.07% (290) POSSIBLE ENOYL-CoA HYDRATASE ECHA13 (ENOYL HYDRASE)
M. thermoresistible (build 8)TH_1273-8e-8059.17% (240) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1970cechA131e-10963.27% (294) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_1568-1e-8955.56% (288) enoyl-CoA hydratase
M. tuberculosis H37RvRv1935cechA131e-10963.27% (294) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-9e-1525.97% (231) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_3859c-1e-2231.75% (252) enoyl-CoA hydratase
M. marinum MMMAR_2863echA131e-11364.75% (295) enoyl-CoA hydratase EchA13
M. avium 104MAV_0670-3e-9356.11% (303) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5886-2e-8953.38% (296) enoyl-CoA hydratase
M. ulcerans Agy99MUL_0754echA49e-2330.16% (252) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4005-1e-11266.09% (289) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1568|M.gilvum_PYR-GCK          -----MQRVADQD------------QVTYETLDEGRIARIWLNRPDAQNA
MSMEG_5886|M.smegmatis_MC2_155      -MPYLLMRWFDMTGSDGDGG--QARQIEYETLDEGRIARIWLNRPQAQNA
MAV_0670|M.avium_104                -----MTLSEQAGAQPGARP--AEELVTYETLDEGRIARIWLNRPDAHNA
Mb1970c|M.bovis_AF2122/97           MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
Rv1935c|M.tuberculosis_H37Rv        MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_2863|M.marinum_M               MNVAGVSPVDRRSNGERAAP--DFTYVRYETIDDGRIATITLNRPKQRNA
Mvan_4005|M.vanbaalenii_PYR-1       -----MQDFDT-----------LFTYLRYELVEQGRVAVITLDRPKQRNA
TH_2027|M.thermoresistible__bu      -----MQMTERTG--------AEYSYVTYEVLDEGRIARIMMNRPRQRNA
MAB_3859c|M.abscessus_ATCC_199      ---------MVDT----------LKTMTYEVTD--RVARITFNRPEQGNA
MUL_0754|M.ulcerans_Agy99           -MTHAIRPVDFDN----------LKTMTYEVTD--RVARITFNRPEKGNA
MLBr_02402|M.leprae_Br4923          -----------------------MKYDTILVDGYQRVGIITLNRPQALNA
                                                                       *:. * ::**   **

Mflv_1568|M.gilvum_PYR-GCK          QSRTLLVQLDEAFGRAEADDVVRVVILAARGKNFSAGHDLGSEAALAERA
MSMEG_5886|M.smegmatis_MC2_155      QSRTLLVQLDEAFARAEADDTVRVVILAARGKNFSAGHDLGSEEALAERE
MAV_0670|M.avium_104                QSRGLLVQLDEAFVRAEADDAVRVVILAARGKNFSAGHDLGSELALAERQ
Mb1970c|M.bovis_AF2122/97           QTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERS
Rv1935c|M.tuberculosis_H37Rv        QTRGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRERS
MMAR_2863|M.marinum_M               QTRGMLVELGAAFELAEADDTVRVVILRGEGPAFSAGHDLGSADDVRERA
Mvan_4005|M.vanbaalenii_PYR-1       QNRGILVELGSAFELAEADDTVRVVILRGAGPSFSAGHDLGSSDDVRERA
TH_2027|M.thermoresistible__bu      QNRGLLVELDDAFMRAERDDDVRVVILGGIGPMFSSGHDLGSSDDRAERS
MAB_3859c|M.abscessus_ATCC_199      IIADTPLELAALVERADLDPQVHVILVSGRGDGFCGGFDLSAYAEANDEG
MUL_0754|M.ulcerans_Agy99           IVADTPLELSALVERADLDPAVQVILVSGRGEGFCAGFDLSAYAEGSSSS
MLBr_02402|M.leprae_Br4923          LNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTD
                                           ::       : *  * .::: .    *..* *:          

Mflv_1568|M.gilvum_PYR-GCK          PGPDQHPTFTCNGATREA-------VIERTYLQEWHYFFNNTSRWRDLRK
MSMEG_5886|M.smegmatis_MC2_155      PGPGQHPTFAGYGATVAG-------VAERTYRQEWHFYFENTKRWRDLRK
MAV_0670|M.avium_104                PGPGQHPTFRFNGATRDP-------IAEKTYLQEWHYFFQNTCRWRDLRK
Mb1970c|M.bovis_AF2122/97           PGPDQHPSYRCNGATFGG-------VESR-NRQEWHYYFENTKRWRNLRK
Rv1935c|M.tuberculosis_H37Rv        PGPDQHPSYRCNGATFGG-------VESR-NRQEWHYYFENTKRWRNLRK
MMAR_2863|M.marinum_M               PGPDQHPTYQCNGGTYGG-------VESR-NRQEWHYYFENTKRWRNLRK
Mvan_4005|M.vanbaalenii_PYR-1       PGPGQHPTYQCNGGTLGG-------VESR-HRQEWHYFFENTRRWRNLRK
TH_2027|M.thermoresistible__bu      GGPAGHPTYLFNGGSRQG-------TEQR-MLQEWHYYFENARRWRNLKK
MAB_3859c|M.abscessus_ATCC_199      SVR--YSGTALDGQVQLRNHLPNINWDPMLDYQMMSRFTRGFSSLLHANK
MUL_0754|M.ulcerans_Agy99           GAEGGYRGTVLDGKAQAVNHLPNQPWDPMIDYQMMSRFVRGFSSLTHADK
MLBr_02402|M.leprae_Br4923          AFD-------AD-------------------------FFSAWGKLAAVRT
                                                                         :           .

Mflv_1568|M.gilvum_PYR-GCK          ITIAQVQGNAISAALMLIWACDLIVASDDAKFSDV---VAVRMGMPGVEY
MSMEG_5886|M.smegmatis_MC2_155      ITIAQVQGNAISAALMLIWACDLIVAADDARFSDV---VAVRMGMPGVEY
MAV_0670|M.avium_104                ITIAQVQGNAISAGLMLIWACDLIVAADNAKFSDV---VGVRMGMPGVEY
Mb1970c|M.bovis_AF2122/97           ITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADV---VGTRLGMCGVEY
Rv1935c|M.tuberculosis_H37Rv        ITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADV---VGTRLGMCGVEY
MMAR_2863|M.marinum_M               ITVAQVHGTVLSAGLMLAWCCDLIVAADDTVFADV---VGTRLGMCGVEY
Mvan_4005|M.vanbaalenii_PYR-1       ITIAEVHGMVLSAGLMLAWCCDLIVAAEDTVFADV---VGTRLGMCGVEF
TH_2027|M.thermoresistible__bu      ITIAETHGPVLAAGLMIAWTCDLIVATPTTTFADV---VGTRIGMCGVEY
MAB_3859c|M.abscessus_ATCC_199      PTVVKVHGYCVAGGTDIALHADQLIVAADAKIGYP---PTRVWGVPATGL
MUL_0754|M.ulcerans_Agy99           PTVVKIHGYCVAGGTDIALHADQVIAAADAKIGYP---PTRVWGVPAAGL
MLBr_02402|M.leprae_Br4923          PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQR
                                      :.   *  :...  :   .* ::.:  : :.          *: .   

Mflv_1568|M.gilvum_PYR-GCK          YAHPWEFGARKAKELLLTGDAIDADEAHRLGMVSKVFPRAELEDKTLEFA
MSMEG_5886|M.smegmatis_MC2_155      YAHPWEFGPRKAKELLLTGDSIDADEAYRLGMVSKVFGREELEDKTLEFA
MAV_0670|M.avium_104                YAHPWEFGPRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFA
Mb1970c|M.bovis_AF2122/97           FGHPWEFGPRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFA
Rv1935c|M.tuberculosis_H37Rv        FGHPWEFGPRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFA
MMAR_2863|M.marinum_M               FGHPWEFGPRKAKELLLTGDSIGADEAHALGMVSKVFPGEDLADSAIEFA
Mvan_4005|M.vanbaalenii_PYR-1       FGHPWEFGPRKAKELLLTGDALGADDAHAIGMVSKVFGNDELSDRAVEFA
TH_2027|M.thermoresistible__bu      FAHPWELGPRRAKELLLTGDSLDAHTAHQWGMVSRIFPDDELQKRTMELA
MAB_3859c|M.abscessus_ATCC_199      WAH--KLGDQRAKRLLLTGDCLSGRQAYDWGLAVEAPEPDELDERTERLV
MUL_0754|M.ulcerans_Agy99           WAH--RLGDQRAKRLLFTGDCITGAQAAEWGLAVEAPDPKDLDERTERLV
MLBr_02402|M.leprae_Br4923          LTR--AIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVA
                                      :   :*  ::  *::**  : .  *   *:. .     :*   :  ..

Mflv_1568|M.gilvum_PYR-GCK          RRIAERPTMAALLVKDSVNAASDAMG--FTEALRHAFHIHELGHAHWAAY
MSMEG_5886|M.smegmatis_MC2_155      RRIAERPTMAALLVKDSVNAAADSMG--FAEALHHAFHIHELGHAHWAAA
MAV_0670|M.avium_104                RRIAERPTMAALLIKDSVNAASDAMG--FTEALRHAFHIHELGHAHWAAH
Mb1970c|M.bovis_AF2122/97           RRIAKVPTMAALLIKESVNQTVDAMG--FSAALDGCFKIHQLNHAHWGEV
Rv1935c|M.tuberculosis_H37Rv        RRIAKVPTMAALLIKESVNQTVDAMG--FSAALDGCFKIHQLNHAHWGEV
MMAR_2863|M.marinum_M               RRIAKLPTMAALLIKESVNQTVDAMG--FTTALDGCFKIHQLNHAHWAEV
Mvan_4005|M.vanbaalenii_PYR-1       GRIAKLPTATALFIKESVNQSVDAMG--FSSALDACFSIHQLNHAYWAEI
TH_2027|M.thermoresistible__bu      QRIAGLPTVTALLIKEAVNQSVDNMG--FYNALNACFSLHQINHAHWAEV
MAB_3859c|M.abscessus_ATCC_199      ERIAAMPLNQLMMIKLACNSVLINQGIANSAMIGTVFDGISRHTPEAHAF
MUL_0754|M.ulcerans_Agy99           ERIAALPVNQLIMIKLALNSALLQQGGVNSRMLSTVFDGVARHTPEGHAF
MLBr_02402|M.leprae_Br4923          TTISQMSRSATRMAKEAVNRSFESTL------AEGLLHERRLFHSTFVTD
                                      *:  .     : * : *                 :       .     

Mflv_1568|M.gilvum_PYR-GCK          NENRYPVGLPPN-VPDWRTLGAPKLSRRDEP
MSMEG_5886|M.smegmatis_MC2_155      NENRWPVGMPPD-VPDWRTLGAPKLARRDTP
MAV_0670|M.avium_104                NENRYPVGLPPD-VEDWRNAKPTRLARRDTP
Mb1970c|M.bovis_AF2122/97           TGGKLSYGTVEYGLEDWRAAPQIRPAIKQRP
Rv1935c|M.tuberculosis_H37Rv        TGGKLSYGTVEYGLEDWRAAPQIRPAIKQRP
MMAR_2863|M.marinum_M               TGGKLCYGTVEYGLDDWRAAPEILPATKRRP
Mvan_4005|M.vanbaalenii_PYR-1       TGNPLGIGTVEDGLEDWQIAPEILPATKNRP
TH_2027|M.thermoresistible__bu      TGGESHLGTPEFGVPRWQDAGPILPRPMSEA
MAB_3859c|M.abscessus_ATCC_199      TADAIANGYRQAVRHRDEPFGDYGRKPTEL-
MUL_0754|M.ulcerans_Agy99           VADAVEHGFRDAVNHRDEPFGDYGRRASSV-
MLBr_02402|M.leprae_Br4923          DQSEGMAAFIEKRAPQFTHR-----------
                                      .    .