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VAEQPIRYEVVDSVAWLTINRPEARNALNNAVRTGLIDAVLRFNDDDAAKVLVLTGVGDKAFCAGGDLKE MAQNALKVPPKDFAPQFGRNIDVAKPTIAAVNGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVGRGSPW ATPLSWLVPPRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRERTQQLALSIAANAPLSVLASKRTVY LSAQHHLAAAYDLADEIWEPVYLSDDAQEGPAAFREKRAPQWKGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2058 | - | - | 100% (255) | enoyl-CoA dehydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 9e-41 | 40.82% (245) | enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_4164 | - | 5e-36 | 40.54% (259) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 4e-33 | 35.95% (242) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4596 | - | 1e-116 | 79.92% (254) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 2e-38 | 39.38% (259) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-31 | 35.95% (242) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4317 | echA1_1 | 9e-41 | 42.00% (250) | enoyl-CoA hydratase, EchA1_1 |
| M. avium 104 | MAV_1277 | - | 2e-43 | 44.40% (250) | carnitinyl-CoA dehydratase |
| M. smegmatis MC2 155 | MSMEG_0335 | - | 8e-95 | 67.87% (249) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_3963 | - | 4e-39 | 38.85% (260) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0972 | echA1_1 | 7e-40 | 41.60% (250) | enoyl-CoA hydratase, EchA1_1 |
| M. vanbaalenii PYR-1 | Mvan_0344 | - | 5e-90 | 64.26% (249) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2058|M.abscessus_ATCC_1997 --------MAEQPIRYEVVDSVAWLTINRPEARNALNNAVRTGLIDAVLR
Mflv_4596|M.gilvum_PYR-GCK --------MSEEAITYEVVDGVAWLTINRPEARNALNGAVRQGLFHSVHR
MSMEG_0335|M.smegmatis_MC2_155 -----------MSVDYEVRNGVAWLTINRPEARNSLNKAVRDGLFDGVRR
Mvan_0344|M.vanbaalenii_PYR-1 -----------MSVTYTVRNGVAWLTIDRPDARNSLNKAVRDGLFDGVRR
MMAR_4317|M.marinum_M ---MTDAGDDQPAGLVEHRGNVMVITINRPEARNAINGAVSVAVGDALES
MUL_0972|M.ulcerans_Agy99 ---MTDAGDDQPAGLVEHRGNVMVITINRPEARNAINGAVSVAVGGALES
MAV_1277|M.avium_104 ---MTDA----PGALAERRGNVMVITINRPEARNAVNAAVSIGVGDALEE
Rv0222|M.tuberculosis_H37Rv MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQ
TH_3963|M.thermoresistible__bu ---VTEQGSSDNPVLVEQRGRILIITINRPEAKNAVNLAVAQGLAAAMDR
Mb1099c|M.bovis_AF2122/97 --------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATE
MLBr_02402|M.leprae_Br4923 --------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKE
: :*::**.* *::* : : .
MAB_2058|M.abscessus_ATCC_1997 FNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQNAL-KVPPKDFAPQFG--R
Mflv_4596|M.gilvum_PYR-GCK FNADDSAKVLVLTGAGDKAFCAGGDLKEMAETAL-TVPPPDFAPQFG--R
MSMEG_0335|M.smegmatis_MC2_155 FNNDAQAKVLVLTGAGDKAFCAGGDLKEMSDDQL-TVPPIDFVPQFG--R
Mvan_0344|M.vanbaalenii_PYR-1 FNADTAAKVLVLTGAGDKAFCAGGDLKEMSADGL-TIPPVDFVPQFG--R
MMAR_4317|M.marinum_M AQNDPEVRAVVITGAGDKSFCAGADLLAISRREN-IYHPDHNEWGFAGYV
MUL_0972|M.ulcerans_Agy99 AQNDAEVRAVVITGAGDKSFCAGADLLAISRREN-IYHPDHNEWGFAGYV
MAV_1277|M.avium_104 AQHDPEVRAVVLTGAGDKSFCAGADLKAIARREN-LYHPDHPEWGFAGYV
Rv0222|M.tuberculosis_H37Rv LDGDAGLSVAILTGGGG-SFCAGMDLKAFARGEN-VVVEGR---GLG-FT
TH_3963|M.thermoresistible__bu LDDDKGLSVGIVTGAGG-SFSAGMDLKAFARGEF-PVVEGR---GLG-YT
Mb1099c|M.bovis_AF2122/97 LDDDPDIGAIIITGSAK-AFAAGADIKEMADLTFADAFTADFFATWG--K
MLBr_02402|M.leprae_Br4923 LDIDPDVGAILITGSPK-VFAAGADIKEMASLTFTDAFDADFFSAWG--K
: * . ::** *.** *: :: .
MAB_2058|M.abscessus_ATCC_1997 NIDVAKPTIAAVNGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG--RG
Mflv_4596|M.gilvum_PYR-GCK NIQVAKPTIAAVNGVAFAGGFLLAQQCDLVIAAEHARFAVSEVKVG--RG
MSMEG_0335|M.smegmatis_MC2_155 NITVDKPTIAAVNGVAFAGGFLLAQTCDLCVASTTAKFAITEAKVG--RG
Mvan_0344|M.vanbaalenii_PYR-1 NIKVDKPTIAAVNGAAFAGGFLLAQTCDLCVASTTATFGITEVKVG--RG
MMAR_4317|M.marinum_M HHFIDKPTIAAVNGTALGGGTELALASDLVVADERAKFGLPEVKRGLIAA
MUL_0972|M.ulcerans_Agy99 HHFIDKPTIAAVNGTALCGGTELALASDLVVADERAKFGLPEAKRGFIAA
MAV_1277|M.avium_104 RHFIDKPTIAAVNGTALGGGTELALASDLVVADERAQFGLPEVKRGLIAA
Rv0222|M.tuberculosis_H37Rv ERPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRGLVAG
TH_3963|M.thermoresistible__bu EKPPAKPLIAAVEGYALAGGTELALAADMIVASRESAFGIPEVKRGLVAG
Mb1099c|M.bovis_AF2122/97 LAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPG
MLBr_02402|M.leprae_Br4923 LAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPG
.* **** * *: ** ** .*: :* : *. .* * * .
MAB_2058|M.abscessus_ATCC_1997 SPWATPLSWLVPPRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRERT
Mflv_4596|M.gilvum_PYR-GCK SPWAVPLSWLLPPRIALQILMTGDPITAERAREVGMVNEVVPAAELRVRV
MSMEG_0335|M.smegmatis_MC2_155 SPWAAPLPLMIPRRIAMELVLTGAPISAARAHEIGFVNRLAEPADLHAVA
Mvan_0344|M.vanbaalenii_PYR-1 SPWAAPLPLMIPRRVVMELVLTGAPMSARRAHEIGFVNRLAEPSDLVDST
MMAR_4317|M.marinum_M AGGVFRIVNQLPRKVAMEMLLTGEPITASDAYEWGLINQVVKQGAVLDAA
MUL_0972|M.ulcerans_Agy99 AGGVFRIVNQLPRKVAMEMLLTGEPITASDAYEWGLINQVVKQGAVLDAA
MAV_1277|M.avium_104 AGGVFRIAEQLPRKVAMRLLLTGEPLSAAAARDWGLINEVVEAGSVLDAA
Rv0222|M.tuberculosis_H37Rv GGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTALDAA
TH_3963|M.thermoresistible__bu GGGLLRLPERIPYSIAMELALTGDILPAERAHDLGLVNALTEPGAALDGA
Mb1099c|M.bovis_AF2122/97 MGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEA
MLBr_02402|M.leprae_Br4923 MGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEA
: : .: : :** : * * *::. :. .
MAB_2058|M.abscessus_ATCC_1997 QQLALSIAANAPLSVLASKRTVYLSAQ---HHLAAAYDLADEIWEPVYLS
Mflv_4596|M.gilvum_PYR-GCK QEIALRIASNAPLSVLAAKKTVYLSAA---HHLTEAYAHADQIWEPVYLS
MSMEG_0335|M.smegmatis_MC2_155 QKLAEQIAANAPLSVAAGKRTATLTAE---HPLSEAFDIAESIWEPVYLS
Mvan_0344|M.vanbaalenii_PYR-1 QALAEQIAANAPLSVAAGKATAVLTAE---YPLSEAYDHAERLWQEVYLS
MMAR_4317|M.marinum_M LALAARVTVNAPLSVRASKRIAYGVDDGVVADEERGWERTMREMRSLIRS
MUL_0972|M.ulcerans_Agy99 LALAARVTVNAPLSVRASKRIAYGVDDGVVADEERGWERTMREMRSLIRS
MAV_1277|M.avium_104 LALASAITVNAPLSVQASKRIAYGVDDGVVVGDEPGWDRTMREMRALLKS
Rv0222|M.tuberculosis_H37Rv IALAEKITANGPLAVVATKRIITESRG---WSPDTMFAEQMKILVPVFTS
TH_3963|M.thermoresistible__bu IELAERIAANGPLAVATTKRIIIESKK---WTPDTMFAEQGKLMAPVFSS
Mb1099c|M.bovis_AF2122/97 RATATTISQMSASAARMAKEAVNRAFES---SLSEGLLYERRLFHSAFAT
MLBr_02402|M.leprae_Br4923 KAVATTISQMSRSATRMAKEAVNRSFES---TLAEGLLHERRLFHSTFVT
* :: . :. * :
MAB_2058|M.abscessus_ATCC_1997 DDAQEGPAAFREKRAPQWKGH
Mflv_4596|M.gilvum_PYR-GCK ADALEGPAAFREKRTPVWKGR
MSMEG_0335|M.smegmatis_MC2_155 GDAQEGMAAFKEKRSPVWKGR
Mvan_0344|M.vanbaalenii_PYR-1 SDAQEGMQAFKDKRAPVWKGI
MMAR_4317|M.marinum_M EDAKEGPLAFAQKREPVWKAR
MUL_0972|M.ulcerans_Agy99 EDAKEGPLAFAEKREPVWKTR
MAV_1277|M.avium_104 EDAKEGPRAFAEKREPVWQAR
Rv0222|M.tuberculosis_H37Rv NDAKEGAIAFAERRRPRWTGT
TH_3963|M.thermoresistible__bu NDAKEGAIAFAEKRAPNWTGT
Mb1099c|M.bovis_AF2122/97 EDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 DDQSEGMAAFIEKRAPQFTHR
* ** ** ::* * :