For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1252 (-)

annotation: putative short chain dehydrogenase
coordinates: 2398582 - 2399337
length: 252

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1252--100% (252)putative short chain dehydrogenase
M. thermoresistible (build 8)TH_3887-1e-2135.47% (203) PUTATIVE short chain dehydrogenase
M. thermoresistible (build 8)TH_3693-6e-1932.43% (222) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2882c-7e-2130.97% (226) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1591-1e-11079.18% (245) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2857c-7e-2130.97% (226) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG15e-1127.37% (179) 3-oxoacyl-
M. abscessus ATCC 19977MAB_1210c-3e-8259.77% (256) putative short chain dehydrogenase/reductase
M. marinum MMMAR_2633-4e-9163.53% (255) short-chain type dehydrogenase/reductase
M. avium 104MAV_2962-6e-9062.99% (254) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155MSMEG_5869-1e-11781.20% (250) putative short chain dehydrogenase
M. ulcerans Agy99MUL_3108-1e-8862.35% (255) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_5166-1e-10373.58% (246) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_1252|M.thermoresistible__bu      -----------------------------------------------VVV
MSMEG_5869|M.smegmatis_MC2_155      ------------------------MVVGGSRGIGLAVAGLLAAQGAGVVV
Mflv_1591|M.gilvum_PYR-GCK          ------------------------------------------------MV
Mvan_5166|M.vanbaalenii_PYR-1       ------------------------MVVGGTRGVGLAVAELLAALGAGVVV
MMAR_2633|M.marinum_M               --------MTDRD----LLAGRGVVVVGGSRGIGRAVAELLARLGAGVVI
MUL_3108|M.ulcerans_Agy99           --------MTDRD----LLAGRGVVVVGGSRGIGRAVAELLARLGAGVVI
MAV_2962|M.avium_104                --------MAAVSGAAALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVV
MAB_1210c|M.abscessus_ATCC_199      --------------------MPNCVVVGGSRGIGRAVALLLGELGTNVVV
Mb2882c|M.bovis_AF2122/97           MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv        MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                                                     :

TH_1252|M.thermoresistible__bu      NGRDPEVVTEAAQRIS-----GVGHAGSPADPAVADALVDTCVQNFGSID
MSMEG_5869|M.smegmatis_MC2_155      NGRDADAAEAAAKRIS-----GVAHAGSPADPAVADALVDTCVTEFGRID
Mflv_1591|M.gilvum_PYR-GCK          NGRDPDAAHEAAQRIPG----ALAHPGSPADPAVADALIDICVREFGRID
Mvan_5166|M.vanbaalenii_PYR-1       NGRDEVAAGQAAERIPR----AIGFSGSPSDPDVADALIDTCVREFGRID
MMAR_2633|M.marinum_M               SGREPDAVRDATEAVISAGGRAAGIAGAADHEDTANALVDRCMTSFGRLD
MUL_3108|M.ulcerans_Agy99           SGREPDAVRDATEAVISAGGRAAGIAGAADHEDTANALVDRCMTSFGRLD
MAV_2962|M.avium_104                NGRDPQAVRETVAAITAAGGRATAVVGAADDERIARSLVDECIGAFGRLD
MAB_1210c|M.abscessus_ATCC_199      NGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGID
Mb2882c|M.bovis_AF2122/97           GDVDVEAGGAAADELSGL-----FVPTDVCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv        GDVDVEAGGAAADELSGL-----FVPTDVCDEDAVNGLFDGAAETYGRID
MLBr_01807|M.leprae_Br4923          ----THRASVVPDWFFG-------VECDVTDNDAIGAAFKAVEEHQGPVE
                                              .   .               .       ..      * ::

TH_1252|M.thermoresistible__bu      ILINCAGTAEPPGSSILNISSGQFRELLDAHLGTVFETCRAAAPRMVAQG
MSMEG_5869|M.smegmatis_MC2_155      ILVNCAGTAEPHGSSILDITSAQFRELLDAHLGTVFETCRAAAPKMVAHG
Mflv_1591|M.gilvum_PYR-GCK          ILINCAGTAEPRGSSILNVTSAQFRELLDAHLGTTFETCRAAAPVMVAQG
Mvan_5166|M.vanbaalenii_PYR-1       ILVNCAGTAEPVGSSILNVTPAQFQELIDAHLGTAFQTCRAAAPLMARQG
MMAR_2633|M.marinum_M               ALINCAGIAEPPGSSILNISPAQFDGLLRAHLGTVFHTCRVAAPVLAAQG
MUL_3108|M.ulcerans_Agy99           ALINCAGIAEPPGSSILNISPAQSDGLLRAHLGTVFHACRVAAPVLAAQG
MAV_2962|M.avium_104                ALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHTCRAAAPVMVEQR
MAB_1210c|M.abscessus_ATCC_199      ALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQR
Mb2882c|M.bovis_AF2122/97           IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
Rv2857c|M.tuberculosis_H37Rv        IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
MLBr_01807|M.leprae_Br4923          VLVANAGITS--DMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
                                      .  ** .   .  *          :  .:*  .:  .: .   :    

TH_1252|M.thermoresistible__bu      GGAIVNTSSFAFLGD--YGGTGYPAGKGGVNGLTLAIAAELKEHSVRANV
MSMEG_5869|M.smegmatis_MC2_155      GGAIVNTGSFAYLGD--YGGTGYPAGKGGVNALTMAIAAELREHKVRANV
Mflv_1591|M.gilvum_PYR-GCK          GGAIVNTGSFAFLGD--YGGTGYPAGKGAVNSLTLAIAAELAEHGVRANV
Mvan_5166|M.vanbaalenii_PYR-1       SGAIVNTSSFAFLGD--YGGTGYAAGKGAVNSLTLAIAAELKEHGIRANV
MMAR_2633|M.marinum_M               HGSIINTGSVAFLGD--YGGSGYPAGKAAVNGLTLAISAELKARGVRANV
MUL_3108|M.ulcerans_Agy99           HGSIINTGSVAFLGD--YGGSGYPAGKAAVNGLTLAISAELKARGVRANV
MAV_2962|M.avium_104                HGSIVNTSSVAFLGD--YGGTGYPAGKGAVNALTMAIAAELKAYGVRANV
MAB_1210c|M.abscessus_ATCC_199      HGAIINTGSTASLGI--YGGTGYPAGKAAVNGLTLAIAAELKRSGVRANV
Mb2882c|M.bovis_AF2122/97           KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
Rv2857c|M.tuberculosis_H37Rv        KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSITANV
                                     *  :  .* . :     .  .*.*.*..: .::  :. ::    : .*.

TH_1252|M.thermoresistible__bu      VCPGARTRLSTGPEYEAHIAELHRRGLLDEVSMQGALDAAPPEYVAPTYA
MSMEG_5869|M.smegmatis_MC2_155      VCPGAKTRLSTGPEYERHIAELNRRGLLDDVSAQGALDAAAPEYAAATYA
Mflv_1591|M.gilvum_PYR-GCK          VCPGAKTRLSTGPEYESHITELNRRGLLDDVSFQGALDAAPPEYVAPTYA
Mvan_5166|M.vanbaalenii_PYR-1       VCPGAKTRLSTGSDYESHIAELNRRGMLDDVSYQGALDAAPPEYAAPTYA
MMAR_2633|M.marinum_M               ICPGARTRLSSGPDYEAHINELHRRGLLDEMTRQASLDAPPADFVAPLYA
MUL_3108|M.ulcerans_Agy99           ICPGARTRLSSGPNYEAHINELHRRGLLDEMTRQASLDAPPADFVAPLYA
MAV_2962|M.avium_104                VCPGARTRLSTGADYERHIEDLHRRGLLDDMTRRASLDSAPPVFVAPVYG
MAB_1210c|M.abscessus_ATCC_199      ICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYA
Mb2882c|M.bovis_AF2122/97           LCPGPVN-----TPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVA
Rv2857c|M.tuberculosis_H37Rv        LCPGPVN-----TPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVA
MLBr_01807|M.leprae_Br4923          VAPGFID-----TEMTRAMDSKYQEAALQ---AIPLGRIGAVEEIAGAVS
                                    :.**        .     :     .                    *   .

TH_1252|M.thermoresistible__bu      YLVSDLAKDITGRIFIAAGGFLGEFARPTPDFLGFRDANDSPPFSVEEIH
MSMEG_5869|M.smegmatis_MC2_155      YLVSDAARDVTGRIFIAAGGFVGEFARPTPGFLGFRDHHTSPPWTADELH
Mflv_1591|M.gilvum_PYR-GCK          YLASDLATQVTGQIFIAAGGFVGRFERQTPSLVAYRGHDDEPPWTVEEIA
Mvan_5166|M.vanbaalenii_PYR-1       YLVSDLANHITGQIFIAAGGFVGRFDRQTPALVAYRGHHDEPPWTVEEIA
MMAR_2633|M.marinum_M               YLASDLASGITGQIFVASGGFVGTFDRPTPRVLGWRDHRADPPWPVEDLH
MUL_3108|M.ulcerans_Agy99           YLASDLASGITGQIFVASGGSVGTFDRPTPRVLGWRDHRADPPWPVEDLH
MAV_2962|M.avium_104                YLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDHHRAGPWSIEEVH
MAB_1210c|M.abscessus_ATCC_199      YLAGDLSARVTGQIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEID
Mb2882c|M.bovis_AF2122/97           FLASDDASFITASTFLVDGGISSAYVTPL---------------------
Rv2857c|M.tuberculosis_H37Rv        FLASDDASFITASTFLVDGGISSAYVTPL---------------------
MLBr_01807|M.leprae_Br4923          FLASEDAGYISGAVIPVDGGLGMGH-------------------------
                                    :*..: :  ::.  : . **    .                         

TH_1252|M.thermoresistible__bu      DMINR------
MSMEG_5869|M.smegmatis_MC2_155      QMISGG-----
Mflv_1591|M.gilvum_PYR-GCK          AQVR-------
Mvan_5166|M.vanbaalenii_PYR-1       AQVG-------
MMAR_2633|M.marinum_M               TMINARLLDTD
MUL_3108|M.ulcerans_Agy99           TMINARLLDTD
MAV_2962|M.avium_104                TMIGAAATP--
MAB_1210c|M.abscessus_ATCC_199      DLMGRR-----
Mb2882c|M.bovis_AF2122/97           -----------
Rv2857c|M.tuberculosis_H37Rv        -----------
MLBr_01807|M.leprae_Br4923          -----------