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PNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDT CRTQYGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTA SLGIYGGTGYPAGKAAVNGLTLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTL QASLVPAPPACVAPLYAYLAGDLSARVTGQIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLM GRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1210c | - | - | 100% (284) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_2948c | - | 2e-22 | 30.74% (296) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0380 | - | 3e-22 | 31.40% (293) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3532c | fabG | 1e-22 | 33.46% (257) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1591 | - | 5e-81 | 59.84% (249) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3502c | fabG | 1e-22 | 33.46% (257) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-14 | 29.67% (182) | 3-oxoacyl- |
| M. marinum M | MMAR_2633 | - | 1e-101 | 64.29% (280) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2962 | - | 1e-101 | 65.47% (278) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_5869 | - | 1e-83 | 56.68% (277) | putative short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_1252 | - | 4e-82 | 59.77% (256) | putative short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_3108 | - | 7e-99 | 63.21% (280) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_5166 | - | 1e-86 | 57.19% (278) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2633|M.marinum_M --------MTDRD----LLAGRGVVVVGGSRGIGRAVAELLARLGAGVVI
MUL_3108|M.ulcerans_Agy99 --------MTDRD----LLAGRGVVVVGGSRGIGRAVAELLARLGAGVVI
MAV_2962|M.avium_104 --------MAAVSGAAALLSGRGAVVSGGSRGIGRAVAELLAGLGAGVVV
MAB_1210c|M.abscessus_ATCC_199 --------------------MPNCVVVGGSRGIGRAVALLLGELGTNVVV
Mflv_1591|M.gilvum_PYR-GCK ------------------------------------------------MV
Mvan_5166|M.vanbaalenii_PYR-1 ------------------------MVVGGTRGVGLAVAELLAALGAGVVV
MSMEG_5869|M.smegmatis_MC2_155 ------------------------MVVGGSRGIGLAVAGLLAAQGAGVVV
TH_1252|M.thermoresistible__bu -----------------------------------------------VVV
Mb3532c|M.bovis_AF2122/97 -MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVV
Rv3502c|M.tuberculosis_H37Rv -MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:
MMAR_2633|M.marinum_M SGRE-----PDAVRDATEAVISAGGRAAGIAGAADHEDTANALVDRCMTS
MUL_3108|M.ulcerans_Agy99 SGRE-----PDAVRDATEAVISAGGRAAGIAGAADHEDTANALVDRCMTS
MAV_2962|M.avium_104 NGRD-----PQAVRETVAAITAAGGRATAVVGAADDERIARSLVDECIGA
MAB_1210c|M.abscessus_ATCC_199 NGRH-----ADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQ
Mflv_1591|M.gilvum_PYR-GCK NGRD-----PDAAHEAAQRIPG----ALAHPGSPADPAVADALIDICVRE
Mvan_5166|M.vanbaalenii_PYR-1 NGRD-----EVAAGQAAERIPR----AIGFSGSPSDPDVADALIDTCVRE
MSMEG_5869|M.smegmatis_MC2_155 NGRD-----ADAAEAAAKRIS-----GVAHAGSPADPAVADALVDTCVTE
TH_1252|M.thermoresistible__bu NGRD-----PEVVTEAAQRIS-----GVGHAGSPADPAVADALVDTCVQN
Mb3532c|M.bovis_AF2122/97 NDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVG-
Rv3502c|M.tuberculosis_H37Rv NDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVG-
MLBr_01807|M.leprae_Br4923 THRA----------------SVVPDWFFGVECDVTDNDAIGAAFKAVEEH
. . . .
MMAR_2633|M.marinum_M FGRLDALINCAGIAEPPGSSILNISPAQFDGLLRAHLGTVFHTCRVAAPV
MUL_3108|M.ulcerans_Agy99 FGRLDALINCAGIAEPPGSSILNISPAQSDGLLRAHLGTVFHACRVAAPV
MAV_2962|M.avium_104 FGRLDALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHTCRAAAPV
MAB_1210c|M.abscessus_ATCC_199 YGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPL
Mflv_1591|M.gilvum_PYR-GCK FGRIDILINCAGTAEPRGSSILNVTSAQFRELLDAHLGTTFETCRAAAPV
Mvan_5166|M.vanbaalenii_PYR-1 FGRIDILVNCAGTAEPVGSSILNVTPAQFQELIDAHLGTAFQTCRAAAPL
MSMEG_5869|M.smegmatis_MC2_155 FGRIDILVNCAGTAEPHGSSILDITSAQFRELLDAHLGTVFETCRAAAPK
TH_1252|M.thermoresistible__bu FGSIDILINCAGTAEPPGSSILNISSGQFRELLDAHLGTVFETCRAAAPR
Mb3532c|M.bovis_AF2122/97 LGGLDIVVNNAGITR--DRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAY
Rv3502c|M.tuberculosis_H37Rv LGGLDIVVNNAGITR--DRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAY
MLBr_01807|M.leprae_Br4923 QGPVEVLVANAGITS--DMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRN
* :: :: ** . . :: :: : :: .:* * : .:
MMAR_2633|M.marinum_M LAAQGH--------GSIINTGSVA-FLGDYGGSGYPAGKAAVNGLTLAIS
MUL_3108|M.ulcerans_Agy99 LAAQGH--------GSIINTGSVA-FLGDYGGSGYPAGKAAVNGLTLAIS
MAV_2962|M.avium_104 MVEQRH--------GSIVNTSSVA-FLGDYGGTGYPAGKGAVNALTMAIA
MAB_1210c|M.abscessus_ATCC_199 MVQQRH--------GAIINTGSTA-SLGIYGGTGYPAGKAAVNGLTLAIA
Mflv_1591|M.gilvum_PYR-GCK MVAQGG--------GAIVNTGSFA-FLGDYGGTGYPAGKGAVNSLTLAIA
Mvan_5166|M.vanbaalenii_PYR-1 MARQGS--------GAIVNTSSFA-FLGDYGGTGYAAGKGAVNSLTLAIA
MSMEG_5869|M.smegmatis_MC2_155 MVAHGG--------GAIVNTGSFA-YLGDYGGTGYPAGKGGVNALTMAIA
TH_1252|M.thermoresistible__bu MVAQGG--------GAIVNTSSFA-FLGDYGGTGYPAGKGGVNGLTLAIA
Mb3532c|M.bovis_AF2122/97 WRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAA
Rv3502c|M.tuberculosis_H37Rv WRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAA
MLBr_01807|M.leprae_Br4923 MIKQRF--------GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLA
: * : .* . * * :.*.*.*..: .:: : :
MMAR_2633|M.marinum_M AELKARGVRANVICPGARTRLSSGPDYEAHINELHRRGLLDEMTRQASLD
MUL_3108|M.ulcerans_Agy99 AELKARGVRANVICPGARTRLSSGPNYEAHINELHRRGLLDEMTRQASLD
MAV_2962|M.avium_104 AELKAYGVRANVVCPGARTRLSTGADYERHIEDLHRRGLLDDMTRRASLD
MAB_1210c|M.abscessus_ATCC_199 AELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLV
Mflv_1591|M.gilvum_PYR-GCK AELAEHGVRANVVCPGAKTRLSTGPEYESHITELNRRGLLDDVSFQGALD
Mvan_5166|M.vanbaalenii_PYR-1 AELKEHGIRANVVCPGAKTRLSTGSDYESHIAELNRRGMLDDVSYQGALD
MSMEG_5869|M.smegmatis_MC2_155 AELREHKVRANVVCPGAKTRLSTGPEYERHIAELNRRGLLDDVSAQGALD
TH_1252|M.thermoresistible__bu AELKEHSVRANVVCPGARTRLSTGPEYEAHIAELHRRGLLDEVSMQGALD
Mb3532c|M.bovis_AF2122/97 RALGRYGVCANVICPRARTAMTADVFGAAPDVEAG------------QID
Rv3502c|M.tuberculosis_H37Rv RALGRYGVCANVICPRARTAMTADVFGAAPDVEAG------------QID
MLBr_01807|M.leprae_Br4923 RELGSRSITANVVAPGFIDTEMTRAMDSKYQEAALQAIPLG--------R
* : ***:.*
MMAR_2633|M.marinum_M APPADFVAPLYAYLASDLASGITGQIFVASGGFVGTFDRPTPRVLGWRDH
MUL_3108|M.ulcerans_Agy99 APPADFVAPLYAYLASDLASGITGQIFVASGGSVGTFDRPTPRVLGWRDH
MAV_2962|M.avium_104 SAPPVFVAPVYGYLVSDLARDVTGQILVAAGGFVGSFDRQTPRLLGYRDH
MAB_1210c|M.abscessus_ATCC_199 PAPPACVAPLYAYLAGDLSARVTGQIFLAAGGFIGRFKRQTPVPLGYRDH
Mflv_1591|M.gilvum_PYR-GCK AAPPEYVAPTYAYLASDLATQVTGQIFIAAGGFVGRFERQTPSLVAYRGH
Mvan_5166|M.vanbaalenii_PYR-1 AAPPEYAAPTYAYLVSDLANHITGQIFIAAGGFVGRFDRQTPALVAYRGH
MSMEG_5869|M.smegmatis_MC2_155 AAAPEYAAATYAYLVSDAARDVTGRIFIAAGGFVGEFARPTPGFLGFRDH
TH_1252|M.thermoresistible__bu AAPPEYVAPTYAYLVSDLAKDITGRIFIAAGGFLGEFARPTPDFLGFRDA
Mb3532c|M.bovis_AF2122/97 PLSPQHVVSLVQFLASPAAAEVNGQVFIVYG---PQVTLVSPPHMERRFS
Rv3502c|M.tuberculosis_H37Rv PLSPQHVVSLVQFLASPAAAEVNGQVFIVYG---PQVTLVSPPHMERRFS
MLBr_01807|M.leprae_Br4923 IGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------------
. . :*.. : :.* :: . *
MMAR_2633|M.marinum_M RADPPWPVEDLHTMINARLLDTD-------------
MUL_3108|M.ulcerans_Agy99 RADPPWPVEDLHTMINARLLDTD-------------
MAV_2962|M.avium_104 HRAGPWSIEEVHTMIGAAATP---------------
MAB_1210c|M.abscessus_ATCC_199 ALDAPWSMEEIDDLMGRR------------------
Mflv_1591|M.gilvum_PYR-GCK DDEPPWTVEEIAAQVR--------------------
Mvan_5166|M.vanbaalenii_PYR-1 HDEPPWTVEEIAAQVG--------------------
MSMEG_5869|M.smegmatis_MC2_155 HTSPPWTADELHQMISGG------------------
TH_1252|M.thermoresistible__bu NDSPPFSVEEIHDMINR-------------------
Mb3532c|M.bovis_AF2122/97 ADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
Rv3502c|M.tuberculosis_H37Rv ADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
MLBr_01807|M.leprae_Br4923 ------------------------------------