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M. bovis AF2122 / 97 Mb1282 (-)

annotation: drug-transport integral membrane protein
coordinates: 1395423 - 1397162
length: 579

MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVP
MLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHR
RGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGVG
LSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIA
IIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAM
TWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA
AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGA
AVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPG
PPGRRAWQADTESTAPSAL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1282--100% (579)drug-transport integral membrane protein
M. bovis AF2122 / 97Mb2361c-3e-5329.93% (421) integral membrane transport protein
M. bovis AF2122 / 97Mb0805cemrB1e-4628.63% (475) multidrug resistance integral membrane efflux protein EmrB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2221-0.062.76% (529) EmrB/QacA family drug resistance transporter
M. tuberculosis H37RvRv1250-0.099.83% (579) drug-transport integral membrane protein
M. leprae Br4923MLBr_01562-6e-3926.63% (398) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_1396-1e-14651.23% (486) EmrB/QacA family drug resistance transporter
M. marinum MMMAR_4192-0.067.41% (540) drug-transport integral membrane protein
M. avium 104MAV_1387-0.068.70% (524) drug transporter
M. smegmatis MC2 155MSMEG_5046-0.064.13% (513) drug transporter
M. thermoresistible (build 8)TH_3965-0.057.89% (551) PUTATIVE drug transporter
M. ulcerans Agy99MUL_0501-4e-4628.33% (473) integral membrane drug efflux protein
M. vanbaalenii PYR-1Mvan_4474-0.056.30% (579) EmrB/QacA family drug resistance transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mb1282|M.bovis_AF2122/97            -----------------------MTTAIRRAAGSSYFRNPWPALW-----
Rv1250|M.tuberculosis_H37Rv         -----------------------MTTAIRRAAGSSYFRNPWPALW-----
MMAR_4192|M.marinum_M               -----------------------MTAVTSRVLDNGYSGNPWNALS-----
MAV_1387|M.avium_104                --------------------------------------------------
Mflv_2221|M.gilvum_PYR-GCK          -----------------------MFDTVTSRAAGT--TNPWPALW-----
Mvan_4474|M.vanbaalenii_PYR-1       -----------------------MFETVTARVRG---ADPWPALW-----
TH_3965|M.thermoresistible__bu      ------------VTSVDAGRS-TMSEVFTAYAPRSAAANPWHALW-----
MSMEG_5046|M.smegmatis_MC2_155      -----------MPSSLNARIAGLLPSRVGALRPQDGTGNPWNALW-----
MAB_1396|M.abscessus_ATCC_1997      -----------------------MRPEYPR---------PWITLW-----
MUL_0501|M.ulcerans_Agy99           ------------MLSTAMDEAHCTPAEVAPPDTRTGTSSPGEHVYPDRLD
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
                                                                                      

Mb1282|M.bovis_AF2122/97            --------AMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA
Rv1250|M.tuberculosis_H37Rv         --------AMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA
MMAR_4192|M.marinum_M               --------AMMIG--FFMIMLDSTIVSIANPTIMAELHIGYADVVWVTSA
MAV_1387|M.avium_104                ---------MMIG--FFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSA
Mflv_2221|M.gilvum_PYR-GCK          --------ALLIG--FFMILVDATIVAVANPAIMASLNAGYDAVIWVTSA
Mvan_4474|M.vanbaalenii_PYR-1       --------ALLIG--FFMILVDATIVPVANPAIMAQLGADYDAVIWVTSA
TH_3965|M.thermoresistible__bu      --------AMLIG--FFMILVDATIVPVANLEIMADLGADYTAVIWVTSA
MSMEG_5046|M.smegmatis_MC2_155      --------AMMFG--FFMILVDATIVSVANPTIMVELGADYDGVIWVTSA
MAB_1396|M.abscessus_ATCC_1997      --------VVLFG--LFMILLDSTIVSVANPAIKAGFGADYSSTVWVTSA
MUL_0501|M.ulcerans_Agy99           AGLLRIAGVCVLA--SLMSVLDATVVGIAQRTFIIEFDSTQAVVAWTMTG
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
                                              :..   ::  :*:*:. :*   :   :        *  :.

Mb1282|M.bovis_AF2122/97            YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA
Rv1250|M.tuberculosis_H37Rv         YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA
MMAR_4192|M.marinum_M               YLLGYAVVLLVAGRLGDRFGPKNLYLIGLSVFTAASMWCGLAGTAAMLIA
MAV_1387|M.avium_104                YLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIA
Mflv_2221|M.gilvum_PYR-GCK          YLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLSDSIGMLIA
Mvan_4474|M.vanbaalenii_PYR-1       YLLAYAVPLLVSGRLGDRYGPKTVYLVGLAVFTAASLWCGLSDSIGMLVA
TH_3965|M.thermoresistible__bu      YLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTIGMLIA
MSMEG_5046|M.smegmatis_MC2_155      YLLAYAVPLLVTGRLGDMYGPKNLYLLGLGVFTAASLWCGLAGSIEMLIA
MAB_1396|M.abscessus_ATCC_1997      YLLGYAVPLLITGRLGDQFGPRSMYLSGLAVFTAASLWCGLAGSIGWLIA
MUL_0501|M.ulcerans_Agy99           YTLALATVIPVAGWAADRFGTKRLWMGSVLAFALGSLLCALAPNILSLIF
MLBr_01562|M.leprae_Br4923          YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
                                    * *  .  : : *  .*  * :  :: .:  *: .*: *.::     *: 

Mb1282|M.bovis_AF2122/97            ARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGTVASVASLVGPL
Rv1250|M.tuberculosis_H37Rv         ARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGTVASVASLVGPL
MMAR_4192|M.marinum_M               ARTVQGIGAGLLTPQTLSTITRIFP-ATRRGAALSLWGAAAGVASLVGPL
MAV_1387|M.avium_104                ARVVQGVGAGVMTPQTLSTITRIFP-AERRGVAVSVWSATAGAASLAGPL
Mflv_2221|M.gilvum_PYR-GCK          ARVVQGVGAALLTPQTMTVITRTFP-AHRRGVAMSVWGATAGVATLVGPL
Mvan_4474|M.vanbaalenii_PYR-1       ARVLQGVGAALLTPQTLTVITRTFP-AHNRGVAMSVWGATAGVATLAGPL
TH_3965|M.thermoresistible__bu      ARVLQGLGAALLTPQTLSMITRIFP-ADRRGVPMGVWGATAGVATLIGPL
MSMEG_5046|M.smegmatis_MC2_155      ARVVQGIGAALLTPQTLSAITRIFP-ANRRGVAMSVWGATAGVATLVGPL
MAB_1396|M.abscessus_ATCC_1997      ARVVQGIGAAMLTPQTLTVVQRVFP-PERRGTAMGVWGAVAGIATLVGPV
MUL_0501|M.ulcerans_Agy99           FRVLQGVGGGMLMPLGFIILTRAAG-PKRLGRLMAAIGIPMLLGPIGGPI
MLBr_01562|M.leprae_Br4923          ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
                                     * :**:*..:  *  :  :          .   .  .     ..: * :

Mb1282|M.bovis_AF2122/97            AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG
Rv1250|M.tuberculosis_H37Rv         AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG
MMAR_4192|M.marinum_M               IGGVLVSGLGWEWIFFVNIPIGLAGLVVAYLLVPDLP-VHAQRFDLIGVG
MAV_1387|M.avium_104                AGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLP-TQSHRFDLVGVG
Mflv_2221|M.gilvum_PYR-GCK          AGGVLVDSLGWQWIFIVNVPVGIVGLVMALRLVPALPNPVRQGFDVPGVV
Mvan_4474|M.vanbaalenii_PYR-1       AGGVLVDSLGWQWIFIVNLPVGVLGFALAVWLVPSLPTARAQRFDLPGVV
TH_3965|M.thermoresistible__bu      AGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMPRLP-RQDQGFDVLGMV
MSMEG_5046|M.smegmatis_MC2_155      AGGVLVGGLGWQWIFFVNVPVGIVGIALAVWLVPTLP-TTRHHFDIPGIV
MAB_1396|M.abscessus_ATCC_1997      AGGLLVDGWGWQWIFYVNVPVGVLGIILGAIYIPRMP-THRHRLDLLGMA
MUL_0501|M.ulcerans_Agy99           LGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSESFDVIGVL
MLBr_01562|M.leprae_Br4923          VGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETH-KERMKLDAAGAI
                                     ** *     *.  * **:*:*:  : :.   .          :*  *  

Mb1282|M.bovis_AF2122/97            LS--GAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAR
Rv1250|M.tuberculosis_H37Rv         LS--GAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAR
MMAR_4192|M.marinum_M               LS--GAGMFLLVFGLQEGQAADWAPWIWAVLVAGVGFMAMFVYWQALNHR
MAV_1387|M.avium_104                LS--GVGMLLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVR
Mflv_2221|M.gilvum_PYR-GCK          LS--GVGLFLIVFALQEGQSHGWALWIWATVLAGVAVMAAFVYWQSINTA
Mvan_4474|M.vanbaalenii_PYR-1       LS--GVALFLIVFALQEGQSHDWAPWIWATIGIGIAVMAAFLYWQSVNTG
TH_3965|M.thermoresistible__bu      LS--AVGLFLIVFALQEAQTHRWAPWIWGTLAGGAGVMAMFVIWQSANRR
MSMEG_5046|M.smegmatis_MC2_155      LS--AVGMFLIVFALQEGQSKDWAPWVWGTATLGVGVMAAFFFWQSVNTR
MAB_1396|M.abscessus_ATCC_1997      LS--AVGMFAFVFALQEGESFQWAPGVWAMMAAGLVVLGVFVWWQSANRG
MUL_0501|M.ulcerans_Agy99           LLSPGLAAFLLALSLIPDRGTVADRYVLIPVIAGLSLIGGFAWHAWHRAD
MLBr_01562|M.leprae_Br4923          LATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAEN-
                                    *   .     :.:.:   .       :          :         .  

Mb1282|M.bovis_AF2122/97            EPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAVCGLSPTHT
Rv1250|M.tuberculosis_H37Rv         EPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHT
MMAR_4192|M.marinum_M               APLISLAIFRDWEFSLCNIGVGITAFATTAPMLPLTFYAQSVCGLSPARA
MAV_1387|M.avium_104                EPLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRS
Mflv_2221|M.gilvum_PYR-GCK          GALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAVCGLTPTRA
Mvan_4474|M.vanbaalenii_PYR-1       EPLIPLIIFGDRNFSMSNLGVATIGFVATGMILPLMFYAQSVCGLTPTQA
TH_3965|M.thermoresistible__bu      HPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGS
MSMEG_5046|M.smegmatis_MC2_155      EPLIPLRVFADRDFTLANIGVAVIGFAVTAMILPLMFYLQTVCGLSPIRS
MAB_1396|M.abscessus_ATCC_1997      EPLIPLRLFADRNFSLAGVGIASMSFCVISTGLPMMFYTQLALGFSPTKA
MUL_0501|M.ulcerans_Agy99           HPLIDLHLFNNSVVTQANLTLLAFAAAYFGSSLLIPTYLQQVLHQTPMQS
MLBr_01562|M.leprae_Br4923          -PVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA
                                     .:: : :* :       : :   .    .  :    : *     :.  :

Mb1282|M.bovis_AF2122/97            AVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMA
Rv1250|M.tuberculosis_H37Rv         AVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMA
MMAR_4192|M.marinum_M               AVLIAPVALASGVLAPVVGMLVDRSHPLPVLGFGFSALAISMTWLSIEMV
MAV_1387|M.avium_104                ALLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMS
Mflv_2221|M.gilvum_PYR-GCK          ALLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGVTWLSIEMT
Mvan_4474|M.vanbaalenii_PYR-1       ALLTAPMAVATGVLAPLVGKLVDRSHPRPVVGFGFALMAIGLTWLSIEMT
TH_3965|M.thermoresistible__bu      ALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLAVEMA
MSMEG_5046|M.smegmatis_MC2_155      ALVTAPTAIASGVLAPFVGRIVDRVHPMPVIGFGFSAMAIGLTWLSIEMA
MAB_1396|M.abscessus_ATCC_1997      ALTQAPTAIVSGILAPLAGWLVDRVRPSILIGGGIALMIASTLWWTLLMR
MUL_0501|M.ulcerans_Agy99           GLYLIPQGLGAMLTMPIASAFMDRRGPGKSVLLGIVLIAVGLAMFTFGVA
MLBr_01562|M.leprae_Br4923          GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN
                                    .:   *  :   :   . . ::.*  *      *   :  .       : 

Mb1282|M.bovis_AF2122/97            PGTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAV
Rv1250|M.tuberculosis_H37Rv         PGTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAV
MMAR_4192|M.marinum_M               PETPVWR-LVLPFAAMGAGMAFVWSPLAATATRNLPAHLAGAGSGVYNAT
MAV_1387|M.avium_104                PATPIWR-LVLPFFAMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSV
Mflv_2221|M.gilvum_PYR-GCK          PTTPIWR-LLLPLTAMGAAMAFIWSPLAATATRNLPPHLAGAGSGVYNTT
Mvan_4474|M.vanbaalenii_PYR-1       PSTPIWR-LVVPLTAMGVAMAFIWSPLAATATRNLPPQLAGAGSGVYNTT
TH_3965|M.thermoresistible__bu      PTTPIWR-LVLPFVAVGVGMAFIWSPLATTATRQLPLHLSGAGSGVYNTT
MSMEG_5046|M.smegmatis_MC2_155      PTTPIWR-LLLPQLLMGIGMAFIWSPLAATATRHLPPDLAGAGSGVYNTT
MAB_1396|M.abscessus_ATCC_1997      PETQMWQ-LMLPAAGIGAAMACIWGPLATTATRNLPPSVAGAGSGVYNTL
MUL_0501|M.ulcerans_Agy99           TRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTLKPREIARGSTLISVT
MLBr_01562|M.leprae_Br4923          RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALML
                                      .     *:      * . .    **: :*   :     .  * :    

Mb1282|M.bovis_AF2122/97            RQLGAVLGSASMAAFMTSRIA-------AEMPGGVDALTGPAGQDATVLQ
Rv1250|M.tuberculosis_H37Rv         RQLGAVLGSASMAAFMTSRIA-------AEMPGGVDALTGPAGQDATVLQ
MMAR_4192|M.marinum_M               RQLGAVLGSASMAAFMTWRIT-------AEMPPGFDADRGFSGGDG-GLQ
MAV_1387|M.avium_104                RQLGAVLGSAGMAAFMTWRIG-------AEMPG----QPGGGGEDSAGPV
Mflv_2221|M.gilvum_PYR-GCK          RQVGSVLGSAGMAALMSSELS-------TKIP-GADAVPQ---SEGEVAA
Mvan_4474|M.vanbaalenii_PYR-1       RQVGSVLGSAAMAALLASQLS-------AKIP-GEAPVP----VEGQAGQ
TH_3965|M.thermoresistible__bu      RQIGSVLGSAGMAAFLTGRLS-------AELPFGATAVP----AGEQTRV
MSMEG_5046|M.smegmatis_MC2_155      RQVGSVLGSAGIAAFMTWRIT-------DEVPGMQDAAPAGE-SGGAVEQ
MAB_1396|M.abscessus_ATCC_1997      RQVGGVVGSSAMGALMTARLT-------ATMP----AMPPGS-GSTPEAA
MUL_0501|M.ulcerans_Agy99           QQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAARGVTVDPSG
MLBr_01562|M.leprae_Br4923          QSLGGPLVLAVIQAVITSRTLYLG------------------GTTGPVKF
                                    :.:*. :  : : :.:: .                               

Mb1282|M.bovis_AF2122/97            LPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD-------------F
Rv1250|M.tuberculosis_H37Rv         LPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD-------------F
MMAR_4192|M.marinum_M               LPEVVRTPFSAAMSQSMLLPAFIAVFGIIAALFLVR-------------S
MAV_1387|M.avium_104                LPEFLRGPFAAAMSQSVLLPAFIALFGIVAALFLVG-------------F
Mflv_2221|M.gilvum_PYR-GCK          LPQFLREPFALAMSQSMLLPAFVALFGVIAALFLFDLLGDRDAAAP--PA
Mvan_4474|M.vanbaalenii_PYR-1       LPAFLHAPFAAAMSQAMLLPAFVALFGVIAALFLVG-LGDRLPAPPRRPQ
TH_3965|M.thermoresistible__bu      LPEFLHAPYAAAMAQSMLLPAFVALFGVLAAIFLAG--------------
MSMEG_5046|M.smegmatis_MC2_155      LPEFLREPFSAAMSQAMLLPAFIALFGVVAALFLLG-------------F
MAB_1396|M.abscessus_ATCC_1997      LPPGLRAPFSAAMAQSMLLGIAALALGLVAALFMRP-------------G
MUL_0501|M.ulcerans_Agy99           LPPQALTPDFADNVMHDLSHAYTVVFGVVVVLVVST--------------
MLBr_01562|M.leprae_Br4923          MNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGY--------------
                                    :      .         *       :  :..:.:                

Mb1282|M.bovis_AF2122/97            TGAAVAKEPLP-------------------ESD--GDADD-DDYVEYILR
Rv1250|M.tuberculosis_H37Rv         TGAAVAKEPLP-------------------ESD--GDADD-DDYVEYILR
MMAR_4192|M.marinum_M               RTAPVRAHDRASHADDDHVDRGDYGYGDYGEQDDFGEQDDYDDYVEFVLR
MAV_1387|M.avium_104                RPWAHRDGGTDAFGPDD------------YGGDYHDDYDDDDAYVELILV
Mflv_2221|M.gilvum_PYR-GCK          PDVEPLEPFDP--------------------DHPLDWADGEDDYVEYEVS
Mvan_4474|M.vanbaalenii_PYR-1       ETAEPVPAFDP--------------------DDELYWADGEDEYVEYEVP
TH_3965|M.thermoresistible__bu      ---IVLSTPQP--------------------DADAQYLDEHDDYLVIELA
MSMEG_5046|M.smegmatis_MC2_155      GSNRAAGHPEP--------------------EHAGDYPD-DDEYVEIILS
MAB_1396|M.abscessus_ATCC_1997      GSQVGAVP------------------------------------LDDVVS
MUL_0501|M.ulcerans_Agy99           ---LIPAASLP---------------------------------------
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1282|M.bovis_AF2122/97            REPEEDCD-----TQPLRASR----------------------PAAAAAS
Rv1250|M.tuberculosis_H37Rv         REPEEDCD-----TQPLRASR----------------------PAAAAAS
MMAR_4192|M.marinum_M               PEPAVGTHRHTEIRRPLSGASGN-------------------GPAVAGRG
MAV_1387|M.avium_104                REPEPEAQQR--AGQPRRPQPTP-------------------APPADVRR
Mflv_2221|M.gilvum_PYR-GCK          REE---FDRLATDG-TADGAAYN-ITEDFTEDITD-----VLDTVVEAPP
Mvan_4474|M.vanbaalenii_PYR-1       WDDGAEPRRPAQEADTVDAAADTDVLDPVTEPMHDGGGYPAPESAPRRDH
TH_3965|M.thermoresistible__bu      RPD----------------------------------------PNPRTDI
MSMEG_5046|M.smegmatis_MC2_155      SDP---------------------------------------------PE
MAB_1396|M.abscessus_ATCC_1997      VED-----------------------------------------------
MUL_0501|M.ulcerans_Agy99           ----------------------------------------------KTPA
MLBr_01562|M.leprae_Br4923          -------------------------------------------------T
                                                                                      

Mb1282|M.bovis_AF2122/97            RSGAGGPLAVSWSTSAQGMPP-------GPPGRRAWQ-------------
Rv1250|M.tuberculosis_H37Rv         RSGAGGPLAVSWSTSAQGMPP-------GPPGRRAWQ-------------
MMAR_4192|M.marinum_M               QQPHSARFEKWRDDAADGHAAPIEHNGARVDARRRFRPVAD---------
MAV_1387|M.avium_104                RDPVESRRSVLDERPAQVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPGPP
Mflv_2221|M.gilvum_PYR-GCK          APADSTPSQQWRDLVDQLLDVS------SPPGAP----RNG---------
Mvan_4474|M.vanbaalenii_PYR-1       ADPTSHPDREWRSILDQLLDPP------KPSDDPTGQGRNG---------
TH_3965|M.thermoresistible__bu      AVTAVIP-ALRPTLRPTLRPSL------GPPGGP----------------
MSMEG_5046|M.smegmatis_MC2_155      DPPTDPQDDRWQHILDRLMQD-------APPEDP----------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_0501|M.ulcerans_Agy99           AAPASFEQHHCDTQYGVHRV------------------------------
MLBr_01562|M.leprae_Br4923          PEQVAYAQEVKEAVDAGEL-------------------------------
                                                                                      

Mb1282|M.bovis_AF2122/97            -------ADTESTAPSAL-------------------------------
Rv1250|M.tuberculosis_H37Rv         -------ADTESTAPSAL-------------------------------
MMAR_4192|M.marinum_M               ---FLPAPDQDDAAGSGHSLP----------------------------
MAV_1387|M.avium_104                ADRFTRPPRRHHPGPAGHHLGEGESLRGQHHRPDPDDDPTGYGRHSSGN
Mflv_2221|M.gilvum_PYR-GCK          ---VGSADAEHPGGGPRV-------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       ---FHVTPSEDGRGASRGRHSLD--------------------------
TH_3965|M.thermoresistible__bu      ------VVQPNNTAALR--------------------------------
MSMEG_5046|M.smegmatis_MC2_155      ---------LPGRGPQRR-------------------------------
MAB_1396|M.abscessus_ATCC_1997      -------------------------------------------------
MUL_0501|M.ulcerans_Agy99           -------------------------------------------------
MLBr_01562|M.leprae_Br4923          -------------------------------------------------