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MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVP MLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHR RGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGVG LSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIA IIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAM TWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGA AVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPG PPGRRAWQADTESTAPSAL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1250 | - | - | 100% (579) | PROBABLE DRUG-TRANSPORT INTEGRAL MEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv2333c | - | 1e-52 | 29.93% (421) | integral membrane transport protein |
M. tuberculosis H37Rv | Rv0783c | emrB | 9e-47 | 28.63% (475) | multidrug resistance integral membrane efflux protein EmrB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1282 | - | 0.0 | 99.83% (579) | drug-transport integral membrane protein |
M. gilvum PYR-GCK | Mflv_2221 | - | 0.0 | 62.57% (529) | EmrB/QacA family drug resistance transporter |
M. leprae Br4923 | MLBr_01562 | - | 8e-39 | 26.63% (398) | putative transmembrane efflux protein |
M. abscessus ATCC 19977 | MAB_1396 | - | 1e-145 | 51.03% (486) | EmrB/QacA family drug resistance transporter |
M. marinum M | MMAR_4192 | - | 0.0 | 67.22% (540) | drug-transport integral membrane protein |
M. avium 104 | MAV_1387 | - | 0.0 | 68.51% (524) | drug transporter |
M. smegmatis MC2 155 | MSMEG_5046 | - | 0.0 | 63.94% (513) | drug transporter |
M. thermoresistible (build 8) | TH_3965 | - | 0.0 | 57.71% (551) | PUTATIVE drug transporter |
M. ulcerans Agy99 | MUL_0501 | - | 3e-46 | 28.33% (473) | integral membrane drug efflux protein |
M. vanbaalenii PYR-1 | Mvan_4474 | - | 0.0 | 56.13% (579) | EmrB/QacA family drug resistance transporter |
CLUSTAL 2.0.9 multiple sequence alignment Rv1250|M.tuberculosis_H37Rv -----------------------MTTAIRRAAGSSYFRNPWPALW----- Mb1282|M.bovis_AF2122/97 -----------------------MTTAIRRAAGSSYFRNPWPALW----- MMAR_4192|M.marinum_M -----------------------MTAVTSRVLDNGYSGNPWNALS----- MAV_1387|M.avium_104 -------------------------------------------------- Mflv_2221|M.gilvum_PYR-GCK -----------------------MFDTVTSRAAGT--TNPWPALW----- Mvan_4474|M.vanbaalenii_PYR-1 -----------------------MFETVTARVRG---ADPWPALW----- TH_3965|M.thermoresistible__bu ------------VTSVDAGRS-TMSEVFTAYAPRSAAANPWHALW----- MSMEG_5046|M.smegmatis_MC2_155 -----------MPSSLNARIAGLLPSRVGALRPQDGTGNPWNALW----- MAB_1396|M.abscessus_ATCC_1997 -----------------------MRPEYPR---------PWITLW----- MUL_0501|M.ulcerans_Agy99 ------------MLSTAMDEAHCTPAEVAPPDTRTGTSSPGEHVYPDRLD MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF Rv1250|M.tuberculosis_H37Rv --------AMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA Mb1282|M.bovis_AF2122/97 --------AMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA MMAR_4192|M.marinum_M --------AMMIG--FFMIMLDSTIVSIANPTIMAELHIGYADVVWVTSA MAV_1387|M.avium_104 ---------MMIG--FFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSA Mflv_2221|M.gilvum_PYR-GCK --------ALLIG--FFMILVDATIVAVANPAIMASLNAGYDAVIWVTSA Mvan_4474|M.vanbaalenii_PYR-1 --------ALLIG--FFMILVDATIVPVANPAIMAQLGADYDAVIWVTSA TH_3965|M.thermoresistible__bu --------AMLIG--FFMILVDATIVPVANLEIMADLGADYTAVIWVTSA MSMEG_5046|M.smegmatis_MC2_155 --------AMMFG--FFMILVDATIVSVANPTIMVELGADYDGVIWVTSA MAB_1396|M.abscessus_ATCC_1997 --------VVLFG--LFMILLDSTIVSVANPAIKAGFGADYSSTVWVTSA MUL_0501|M.ulcerans_Agy99 AGLLRIAGVCVLA--SLMSVLDATVVGIAQRTFIIEFDSTQAVVAWTMTG MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA :.. :: :*:*:. :* : : * :. Rv1250|M.tuberculosis_H37Rv YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA Mb1282|M.bovis_AF2122/97 YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA MMAR_4192|M.marinum_M YLLGYAVVLLVAGRLGDRFGPKNLYLIGLSVFTAASMWCGLAGTAAMLIA MAV_1387|M.avium_104 YLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIA Mflv_2221|M.gilvum_PYR-GCK YLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLSDSIGMLIA Mvan_4474|M.vanbaalenii_PYR-1 YLLAYAVPLLVSGRLGDRYGPKTVYLVGLAVFTAASLWCGLSDSIGMLVA TH_3965|M.thermoresistible__bu YLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTIGMLIA MSMEG_5046|M.smegmatis_MC2_155 YLLAYAVPLLVTGRLGDMYGPKNLYLLGLGVFTAASLWCGLAGSIEMLIA MAB_1396|M.abscessus_ATCC_1997 YLLGYAVPLLITGRLGDQFGPRSMYLSGLAVFTAASLWCGLAGSIGWLIA MUL_0501|M.ulcerans_Agy99 YTLALATVIPVAGWAADRFGTKRLWMGSVLAFALGSLLCALAPNILSLIF MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI * * . : : * .* * : :: .: *: .*: *.:: *: Rv1250|M.tuberculosis_H37Rv ARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGTVASVASLVGPL Mb1282|M.bovis_AF2122/97 ARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGTVASVASLVGPL MMAR_4192|M.marinum_M ARTVQGIGAGLLTPQTLSTITRIFP-ATRRGAALSLWGAAAGVASLVGPL MAV_1387|M.avium_104 ARVVQGVGAGVMTPQTLSTITRIFP-AERRGVAVSVWSATAGAASLAGPL Mflv_2221|M.gilvum_PYR-GCK ARVVQGVGAALLTPQTMTVITRTFP-AHRRGVAMSVWGATAGVATLVGPL Mvan_4474|M.vanbaalenii_PYR-1 ARVLQGVGAALLTPQTLTVITRTFP-AHNRGVAMSVWGATAGVATLAGPL TH_3965|M.thermoresistible__bu ARVLQGLGAALLTPQTLSMITRIFP-ADRRGVPMGVWGATAGVATLIGPL MSMEG_5046|M.smegmatis_MC2_155 ARVVQGIGAALLTPQTLSAITRIFP-ANRRGVAMSVWGATAGVATLVGPL MAB_1396|M.abscessus_ATCC_1997 ARVVQGIGAAMLTPQTLTVVQRVFP-PERRGTAMGVWGAVAGIATLVGPV MUL_0501|M.ulcerans_Agy99 FRVLQGVGGGMLMPLGFIILTRAAG-PKRLGRLMAAIGIPMLLGPIGGPI MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV * :**:*..: * : : . . . ..: * : Rv1250|M.tuberculosis_H37Rv AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG Mb1282|M.bovis_AF2122/97 AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG MMAR_4192|M.marinum_M IGGVLVSGLGWEWIFFVNIPIGLAGLVVAYLLVPDLP-VHAQRFDLIGVG MAV_1387|M.avium_104 AGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLP-TQSHRFDLVGVG Mflv_2221|M.gilvum_PYR-GCK AGGVLVDSLGWQWIFIVNVPVGIVGLVMALRLVPALPNPVRQGFDVPGVV Mvan_4474|M.vanbaalenii_PYR-1 AGGVLVDSLGWQWIFIVNLPVGVLGFALAVWLVPSLPTARAQRFDLPGVV TH_3965|M.thermoresistible__bu AGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMPRLP-RQDQGFDVLGMV MSMEG_5046|M.smegmatis_MC2_155 AGGVLVGGLGWQWIFFVNVPVGIVGIALAVWLVPTLP-TTRHHFDIPGIV MAB_1396|M.abscessus_ATCC_1997 AGGLLVDGWGWQWIFYVNVPVGVLGIILGAIYIPRMP-THRHRLDLLGMA MUL_0501|M.ulcerans_Agy99 LGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSESFDVIGVL MLBr_01562|M.leprae_Br4923 VGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETH-KERMKLDAAGAI ** * *. * **:*:*: : :. . :* * Rv1250|M.tuberculosis_H37Rv LS--GAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAR Mb1282|M.bovis_AF2122/97 LS--GAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAR MMAR_4192|M.marinum_M LS--GAGMFLLVFGLQEGQAADWAPWIWAVLVAGVGFMAMFVYWQALNHR MAV_1387|M.avium_104 LS--GVGMLLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVR Mflv_2221|M.gilvum_PYR-GCK LS--GVGLFLIVFALQEGQSHGWALWIWATVLAGVAVMAAFVYWQSINTA Mvan_4474|M.vanbaalenii_PYR-1 LS--GVALFLIVFALQEGQSHDWAPWIWATIGIGIAVMAAFLYWQSVNTG TH_3965|M.thermoresistible__bu LS--AVGLFLIVFALQEAQTHRWAPWIWGTLAGGAGVMAMFVIWQSANRR MSMEG_5046|M.smegmatis_MC2_155 LS--AVGMFLIVFALQEGQSKDWAPWVWGTATLGVGVMAAFFFWQSVNTR MAB_1396|M.abscessus_ATCC_1997 LS--AVGMFAFVFALQEGESFQWAPGVWAMMAAGLVVLGVFVWWQSANRG MUL_0501|M.ulcerans_Agy99 LLSPGLAAFLLALSLIPDRGTVADRYVLIPVIAGLSLIGGFAWHAWHRAD MLBr_01562|M.leprae_Br4923 LATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAEN- * . :.:.: . : : . Rv1250|M.tuberculosis_H37Rv EPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHT Mb1282|M.bovis_AF2122/97 EPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAVCGLSPTHT MMAR_4192|M.marinum_M APLISLAIFRDWEFSLCNIGVGITAFATTAPMLPLTFYAQSVCGLSPARA MAV_1387|M.avium_104 EPLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRS Mflv_2221|M.gilvum_PYR-GCK GALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAVCGLTPTRA Mvan_4474|M.vanbaalenii_PYR-1 EPLIPLIIFGDRNFSMSNLGVATIGFVATGMILPLMFYAQSVCGLTPTQA TH_3965|M.thermoresistible__bu HPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGS MSMEG_5046|M.smegmatis_MC2_155 EPLIPLRVFADRDFTLANIGVAVIGFAVTAMILPLMFYLQTVCGLSPIRS MAB_1396|M.abscessus_ATCC_1997 EPLIPLRLFADRNFSLAGVGIASMSFCVISTGLPMMFYTQLALGFSPTKA MUL_0501|M.ulcerans_Agy99 HPLIDLHLFNNSVVTQANLTLLAFAAAYFGSSLLIPTYLQQVLHQTPMQS MLBr_01562|M.leprae_Br4923 -PVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA .:: : :* : : : . . : : * :. : Rv1250|M.tuberculosis_H37Rv AVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMA Mb1282|M.bovis_AF2122/97 AVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMA MMAR_4192|M.marinum_M AVLIAPVALASGVLAPVVGMLVDRSHPLPVLGFGFSALAISMTWLSIEMV MAV_1387|M.avium_104 ALLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMS Mflv_2221|M.gilvum_PYR-GCK ALLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGVTWLSIEMT Mvan_4474|M.vanbaalenii_PYR-1 ALLTAPMAVATGVLAPLVGKLVDRSHPRPVVGFGFALMAIGLTWLSIEMT TH_3965|M.thermoresistible__bu ALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLAVEMA MSMEG_5046|M.smegmatis_MC2_155 ALVTAPTAIASGVLAPFVGRIVDRVHPMPVIGFGFSAMAIGLTWLSIEMA MAB_1396|M.abscessus_ATCC_1997 ALTQAPTAIVSGILAPLAGWLVDRVRPSILIGGGIALMIASTLWWTLLMR MUL_0501|M.ulcerans_Agy99 GLYLIPQGLGAMLTMPIASAFMDRRGPGKSVLLGIVLIAVGLAMFTFGVA MLBr_01562|M.leprae_Br4923 GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN .: * : : . . ::.* * * : . : Rv1250|M.tuberculosis_H37Rv PGTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAV Mb1282|M.bovis_AF2122/97 PGTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAV MMAR_4192|M.marinum_M PETPVWR-LVLPFAAMGAGMAFVWSPLAATATRNLPAHLAGAGSGVYNAT MAV_1387|M.avium_104 PATPIWR-LVLPFFAMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSV Mflv_2221|M.gilvum_PYR-GCK PTTPIWR-LLLPLTAMGAAMAFIWSPLAATATRNLPPHLAGAGSGVYNTT Mvan_4474|M.vanbaalenii_PYR-1 PSTPIWR-LVVPLTAMGVAMAFIWSPLAATATRNLPPQLAGAGSGVYNTT TH_3965|M.thermoresistible__bu PTTPIWR-LVLPFVAVGVGMAFIWSPLATTATRQLPLHLSGAGSGVYNTT MSMEG_5046|M.smegmatis_MC2_155 PTTPIWR-LLLPQLLMGIGMAFIWSPLAATATRHLPPDLAGAGSGVYNTT MAB_1396|M.abscessus_ATCC_1997 PETQMWQ-LMLPAAGIGAAMACIWGPLATTATRNLPPSVAGAGSGVYNTL MUL_0501|M.ulcerans_Agy99 TRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTLKPREIARGSTLISVT MLBr_01562|M.leprae_Br4923 RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALML . *: * . . **: :* : . * : Rv1250|M.tuberculosis_H37Rv RQLGAVLGSASMAAFMTSRIA-------AEMPGGVDALTGPAGQDATVLQ Mb1282|M.bovis_AF2122/97 RQLGAVLGSASMAAFMTSRIA-------AEMPGGVDALTGPAGQDATVLQ MMAR_4192|M.marinum_M RQLGAVLGSASMAAFMTWRIT-------AEMPPGFDADRGFSGGDG-GLQ MAV_1387|M.avium_104 RQLGAVLGSAGMAAFMTWRIG-------AEMPG----QPGGGGEDSAGPV Mflv_2221|M.gilvum_PYR-GCK RQVGSVLGSAGMAALMSSELS-------TKIP-GADAVPQ---SEGEVAA Mvan_4474|M.vanbaalenii_PYR-1 RQVGSVLGSAAMAALLASQLS-------AKIP-GEAPVP----VEGQAGQ TH_3965|M.thermoresistible__bu RQIGSVLGSAGMAAFLTGRLS-------AELPFGATAVP----AGEQTRV MSMEG_5046|M.smegmatis_MC2_155 RQVGSVLGSAGIAAFMTWRIT-------DEVPGMQDAAPAGE-SGGAVEQ MAB_1396|M.abscessus_ATCC_1997 RQVGGVVGSSAMGALMTARLT-------ATMP----AMPPGS-GSTPEAA MUL_0501|M.ulcerans_Agy99 QQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAARGVTVDPSG MLBr_01562|M.leprae_Br4923 QSLGGPLVLAVIQAVITSRTLYLG------------------GTTGPVKF :.:*. : : : :.:: . Rv1250|M.tuberculosis_H37Rv LPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD-------------F Mb1282|M.bovis_AF2122/97 LPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD-------------F MMAR_4192|M.marinum_M LPEVVRTPFSAAMSQSMLLPAFIAVFGIIAALFLVR-------------S MAV_1387|M.avium_104 LPEFLRGPFAAAMSQSVLLPAFIALFGIVAALFLVG-------------F Mflv_2221|M.gilvum_PYR-GCK LPQFLREPFALAMSQSMLLPAFVALFGVIAALFLFDLLGDRDAAAP--PA Mvan_4474|M.vanbaalenii_PYR-1 LPAFLHAPFAAAMSQAMLLPAFVALFGVIAALFLVG-LGDRLPAPPRRPQ TH_3965|M.thermoresistible__bu LPEFLHAPYAAAMAQSMLLPAFVALFGVLAAIFLAG-------------- MSMEG_5046|M.smegmatis_MC2_155 LPEFLREPFSAAMSQAMLLPAFIALFGVVAALFLLG-------------F MAB_1396|M.abscessus_ATCC_1997 LPPGLRAPFSAAMAQSMLLGIAALALGLVAALFMRP-------------G MUL_0501|M.ulcerans_Agy99 LPPQALTPDFADNVMHDLSHAYTVVFGVVVVLVVST-------------- MLBr_01562|M.leprae_Br4923 MNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGY-------------- : . * : :..:.: Rv1250|M.tuberculosis_H37Rv TGAAVAKEPLP-------------------ESD--GDADD-DDYVEYILR Mb1282|M.bovis_AF2122/97 TGAAVAKEPLP-------------------ESD--GDADD-DDYVEYILR MMAR_4192|M.marinum_M RTAPVRAHDRASHADDDHVDRGDYGYGDYGEQDDFGEQDDYDDYVEFVLR MAV_1387|M.avium_104 RPWAHRDGGTDAFGPDD------------YGGDYHDDYDDDDAYVELILV Mflv_2221|M.gilvum_PYR-GCK PDVEPLEPFDP--------------------DHPLDWADGEDDYVEYEVS Mvan_4474|M.vanbaalenii_PYR-1 ETAEPVPAFDP--------------------DDELYWADGEDEYVEYEVP TH_3965|M.thermoresistible__bu ---IVLSTPQP--------------------DADAQYLDEHDDYLVIELA MSMEG_5046|M.smegmatis_MC2_155 GSNRAAGHPEP--------------------EHAGDYPD-DDEYVEIILS MAB_1396|M.abscessus_ATCC_1997 GSQVGAVP------------------------------------LDDVVS MUL_0501|M.ulcerans_Agy99 ---LIPAASLP--------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- Rv1250|M.tuberculosis_H37Rv REPEEDCD-----TQPLRASR----------------------PAAAAAS Mb1282|M.bovis_AF2122/97 REPEEDCD-----TQPLRASR----------------------PAAAAAS MMAR_4192|M.marinum_M PEPAVGTHRHTEIRRPLSGASGN-------------------GPAVAGRG MAV_1387|M.avium_104 REPEPEAQQR--AGQPRRPQPTP-------------------APPADVRR Mflv_2221|M.gilvum_PYR-GCK REE---FDRLATDG-TADGAAYN-ITEDFTEDITD-----VLDTVVEAPP Mvan_4474|M.vanbaalenii_PYR-1 WDDGAEPRRPAQEADTVDAAADTDVLDPVTEPMHDGGGYPAPESAPRRDH TH_3965|M.thermoresistible__bu RPD----------------------------------------PNPRTDI MSMEG_5046|M.smegmatis_MC2_155 SDP---------------------------------------------PE MAB_1396|M.abscessus_ATCC_1997 VED----------------------------------------------- MUL_0501|M.ulcerans_Agy99 ----------------------------------------------KTPA MLBr_01562|M.leprae_Br4923 -------------------------------------------------T Rv1250|M.tuberculosis_H37Rv RSGAGGPLAVSWSTSAQGMPP-------GPPGRRAWQ------------- Mb1282|M.bovis_AF2122/97 RSGAGGPLAVSWSTSAQGMPP-------GPPGRRAWQ------------- MMAR_4192|M.marinum_M QQPHSARFEKWRDDAADGHAAPIEHNGARVDARRRFRPVAD--------- MAV_1387|M.avium_104 RDPVESRRSVLDERPAQVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPGPP Mflv_2221|M.gilvum_PYR-GCK APADSTPSQQWRDLVDQLLDVS------SPPGAP----RNG--------- Mvan_4474|M.vanbaalenii_PYR-1 ADPTSHPDREWRSILDQLLDPP------KPSDDPTGQGRNG--------- TH_3965|M.thermoresistible__bu AVTAVIP-ALRPTLRPTLRPSL------GPPGGP---------------- MSMEG_5046|M.smegmatis_MC2_155 DPPTDPQDDRWQHILDRLMQD-------APPEDP---------------- MAB_1396|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0501|M.ulcerans_Agy99 AAPASFEQHHCDTQYGVHRV------------------------------ MLBr_01562|M.leprae_Br4923 PEQVAYAQEVKEAVDAGEL------------------------------- Rv1250|M.tuberculosis_H37Rv -------ADTESTAPSAL------------------------------- Mb1282|M.bovis_AF2122/97 -------ADTESTAPSAL------------------------------- MMAR_4192|M.marinum_M ---FLPAPDQDDAAGSGHSLP---------------------------- MAV_1387|M.avium_104 ADRFTRPPRRHHPGPAGHHLGEGESLRGQHHRPDPDDDPTGYGRHSSGN Mflv_2221|M.gilvum_PYR-GCK ---VGSADAEHPGGGPRV------------------------------- Mvan_4474|M.vanbaalenii_PYR-1 ---FHVTPSEDGRGASRGRHSLD-------------------------- TH_3965|M.thermoresistible__bu ------VVQPNNTAALR-------------------------------- MSMEG_5046|M.smegmatis_MC2_155 ---------LPGRGPQRR------------------------------- MAB_1396|M.abscessus_ATCC_1997 ------------------------------------------------- MUL_0501|M.ulcerans_Agy99 ------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------