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M. thermoresistible (build 8) TH_0280 (-)

annotation: oxidoreductase, zinc-binding dehydrogenase family protein
coordinates: 627061 - 628029
length: 323

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0280--100% (323)oxidoreductase, zinc-binding dehydrogenase family protein
M. thermoresistible (build 8)TH_3466-2e-0629.35% (201) PUTATIVE Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)TH_2558-3e-0624.30% (284) PUTATIVE putative aryl-alcohol dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1929-4e-0828.88% (187) dehydrogenase
M. gilvum PYR-GCKMflv_4106-1e-13974.38% (320) alcohol dehydrogenase
M. tuberculosis H37RvRv1895-5e-1128.73% (268) dehydrogenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0526c-2e-0927.69% (242) hypothetical protein MAB_0526c
M. marinum MMMAR_0400-1e-13071.25% (320) dehydrogenase
M. avium 104MAV_5122-1e-13273.29% (322) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_2564-1e-14275.00% (320) oxidoreductase, zinc-binding dehydrogenase family protein
M. ulcerans Agy99MUL_2962-8e-1229.10% (268) dehydrogenase
M. vanbaalenii PYR-1Mvan_2240-1e-14376.01% (321) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4106|M.gilvum_PYR-GCK          MWSYRLVAPYTFERTEQPQRSPESLAENQVLLRFLAGGICGSDLPGFRGA
Mvan_2240|M.vanbaalenii_PYR-1       MWSYRLVAPFIFEKADVPQRCPESLGDGQVLLRFLAAGICGSDLPGYRGA
TH_0280|M.thermoresistible__bu      MWAYRLTAPYRFDRIEVPEPDPDGLRDGQVLLRFLAAGVCGSDLPGFRGT
MSMEG_2564|M.smegmatis_MC2_155      MWSYRLVAPYVFERSDLRAPSPDALTDGQVLLSFSAAGICGSDIPGFRGT
MMAR_0400|M.marinum_M               MWSYRIIAPYLFERTSIADKTPECLAEGQVLLRFQAAGVCGSDLPAFRGA
MAV_5122|M.avium_104                MWCYRIVAPYRFEPTAIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGA
Mb1929|M.bovis_AF2122/97            --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv         MRAVVIDGAGSVRVNTQPD--PALPGPDGVVVAVTAAGICGSDLHFYEGE
MUL_2962|M.ulcerans_Agy99           MRTVVIDGPGSIRVDNRPD--PALPGSDGVIVVVSAAGICGSDLHFYEGE
MAB_0526c|M.abscessus_ATCC_199      MRASVLRNGSMVYRDDVPS---PTPGEGQVLVKVSACGICGSDLHFAKHG
                                                                                      

Mflv_4106|M.gilvum_PYR-GCK          RGRLA---------------FDTGRQAAEKDGFPIHEVVGEVLASRHLAH
Mvan_2240|M.vanbaalenii_PYR-1       KGRLA---------------GDTGACAAEMDGFPIHEIAGEVIASRHPAH
TH_0280|M.thermoresistible__bu      QGRLP---------------GDTGVSTCEIPGFPIHEIAGEVIASRHPQH
MSMEG_2564|M.smegmatis_MC2_155      QGKLP---------------GDTGASAAQMPGFPIHEIAGEVLASRHPDH
MMAR_0400|M.marinum_M               RGHLP---------------GDDGHSAAAKDGFPIHEVAGEVIASRHRAH
MAV_5122|M.avium_104                RGRLP---------------GDDGRSGPEKDGFPIHEVAGEVIASRHPAH
Mb1929|M.bovis_AF2122/97            --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv         YPFTEPVALGHEAVGTIVEAGPQVRTVGVGDLVMVSSVAGCGVCPGCETH
MUL_2962|M.ulcerans_Agy99           YPLAEPVALGHEAVGTVVEKGPDVHTVEVGDQVMVSSVAGCGACAGCATR
MAB_0526c|M.abscessus_ATCC_199      ARAIELSKQMVG------MPSLTDGVDLSTDVFMGHEFAAEVIEAGPRTQ
                                                                                      

Mflv_4106|M.gilvum_PYR-GCK          T-----PGDRVVG--WASGFD----------GLAEEVVADGEGLASYDPS
Mvan_2240|M.vanbaalenii_PYR-1       R-----PGDRVVG--WASGFD----------GLMEQVIADGDGLVAYHGS
TH_0280|M.thermoresistible__bu      H-----PGDRVVG--WASGFD----------GLQARVTADGDGLARYDAA
MSMEG_2564|M.smegmatis_MC2_155      R-----VGDHVVG--WASGFD----------GLMEQVIADGDGLVSYDPA
MMAR_0400|M.marinum_M               H-----QGDRVVG--WASGFD----------GLMQRVIADGDGLAPYDPG
MAV_5122|M.avium_104                R-----PGDRVVG--WASGFD----------GLMERVVSDGDGLAPYDPA
Mb1929|M.bovis_AF2122/97            ---------MIFGAGVLGGAQ----------ADLLAVPAADFQVLKIPEG
Rv1895|M.tuberculosis_H37Rv         DPVMCFSGPMIFGAGVLGGAQ----------ADLLAVPAADFQVLKIPEG
MUL_2962|M.ulcerans_Agy99           DPAMCVSGPQIFGSGALGGAQ----------ADLLAVPATDFQVLKIPAA
MAB_0526c|M.abscessus_ATCC_199      APASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLLSAPLLLPIPNG
                                              :       * :          .    :      :     .

Mflv_4106|M.gilvum_PYR-GCK          LDPAHAVALQP-LACVLYAVEQMPDLAGRHVAILGQGSIGLLFSYVAKAA
Mvan_2240|M.vanbaalenii_PYR-1       LSPAHAVALQP-LACVLYAVEQLPDLTGRHVAVLGQGSIGLLFSHAAKAA
TH_0280|M.thermoresistible__bu      LEPRHAVALQP-LACVLYAVEQLGDLTGRRVAVIGQGSIGLLFSYVAKAA
MSMEG_2564|M.smegmatis_MC2_155      LPPRLAVGLQP-LACVLCAVEQLPDLDGRHVAVIGQGSIGLLFSYVAKAL
MMAR_0400|M.marinum_M               LTPTQAVGLQP-LACVLYACAQLPDLAGRHVAVIGQGSIGLLFSHAAKVA
MAV_5122|M.avium_104                LSPAQAVGLQP-LACVLYACEQL-ELAGKHVAIIGQGSIGLLFSYVAKAA
Mb1929|M.bovis_AF2122/97            ITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFIH
Rv1895|M.tuberculosis_H37Rv         ITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFIH
MUL_2962|M.ulcerans_Agy99           ITTEQALLLTDNLATGWAAARRADIPFGATVAVIGLGAVGLCAVRSALAQ
MAB_0526c|M.abscessus_ATCC_199      LDPRHAALTEP-MAVGLHAVNKSAIQPGTGAIVIGCGPVGIAVIAALHNL
                                    : .  *      :*    *  :     *  . ::* *.:*:         

Mflv_4106|M.gilvum_PYR-GCK          GAAHVTGVDPVDRSAVGAAFGVDTVVRATSDRWVSHLGA--DDRPDVVIE
Mvan_2240|M.vanbaalenii_PYR-1       GAAHVTGVDPVDRDDVGPSFGVDTVVRATSDRWVSRLAP--DAKPDIVIE
TH_0280|M.thermoresistible__bu      GAAHVTGVDPVDRELVGKEFGVDTVVRATSDRWIRHLGA--DDRADVVIE
MSMEG_2564|M.smegmatis_MC2_155      GAARVTGVDPLDRSAIAARFGIDTPVRATSDRWVTHLDP--DDRADVVIE
MMAR_0400|M.marinum_M               GARRVTGVDPIDRENLSATFGVDDAVRATSDRWVSQLGA--GDRADIVIE
MAV_5122|M.avium_104                GARRVTGVDPIDRRDVARAFGVDDPVRATSDRWVSQLDP--ADRADVVIE
Mb1929|M.bovis_AF2122/97            GAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR--GRGADSVID
Rv1895|M.tuberculosis_H37Rv         GAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR--GRGADSVID
MUL_2962|M.ulcerans_Agy99           GAATVFAVDRVQGRLQRAAEWGATAVASPAAEAIVAATS--GRGADSVID
MAB_0526c|M.abscessus_ATCC_199      GIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
                                    *   : . *  .             :  .  .            .  :::

Mflv_4106|M.gilvum_PYR-GCK          AVGHQVATLTHAVEAAAFGGFVFYFGVPDDDWYPISMRTMLRNNLTLKAG
Mvan_2240|M.vanbaalenii_PYR-1       AVGHQVATLSHAVEAAAFGGTVFYFGVPDDDCYPISMRTMLRNNLTLKSG
TH_0280|M.thermoresistible__bu      AVGHQVATLNHAIEATAFGGTVFYFGVPDDDSYPINMRAMLRNNLTLKSG
MSMEG_2564|M.smegmatis_MC2_155      AVGHQVATLNHALTAAAFGGTVFYFGVPDDDSYPISMRTMLRNNLTLKSG
MMAR_0400|M.marinum_M               AVGHQVATLGHAIDAAAPGGTVFYFGVADDDAYPISMRTMLRNNLTLKSG
MAV_5122|M.avium_104                AVGHQVATLAHAIDAAAPGGTVFYFGVADDDTYPISMRTMLRNNLTLKSG
Mb1929|M.bovis_AF2122/97            AVGTDAS-MSDALNAVRPGGTVSVVGVHDLQPFPLPALTCLLRSITLRMT
Rv1895|M.tuberculosis_H37Rv         AVGTDAS-MSDALNAVRPGGTVSVVGVHDLQPFPVPALTCLLRSITLRMT
MUL_2962|M.ulcerans_Agy99           AVDTDAS-MTDALNAVRAGGTVSVVGVHDLQPFPLPALTCLLRSITLRLT
MAB_0526c|M.abscessus_ATCC_199      AVG-VPGILNEVLRDAPRSARVVVVGVC-MEPDAITPYFGIAKEVAVQFV
                                    **.   . : ..:  .  .. *  .**   :  .:     : ..::::  

Mflv_4106|M.gilvum_PYR-GCK          VTLERRRVLRCADEFAAAHPGLLDRYLTHTFGVDDVQQAFELAARPVPGR
Mvan_2240|M.vanbaalenii_PYR-1       VTIERRRVLAKADAFVQEHPGLLERYLTHTFGVDEAPAAFELASRPVPGR
TH_0280|M.thermoresistible__bu      VTLDRRRMLARADAFAREHSDLLTRYLTHTFGADEAQAAFELACRPAPER
MSMEG_2564|M.smegmatis_MC2_155      VTTDRQRVLRRADTFAREHPHLLPGYVTHTFGVDDVQAAFELACRPVPDR
MMAR_0400|M.marinum_M               VTQDRRRMLELAGKFAAEHPELLSGYLTHNFDVEDVQAAFELACRPVPER
MAV_5122|M.avium_104                VTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDEVQDAFELACRPVADR
Mb1929|M.bovis_AF2122/97            MAPVQRTWPELIPLLQSGR-LDVDGIFTTTLPLDEAAKGYATARARSGEE
Rv1895|M.tuberculosis_H37Rv         MAPVQRTWPELIPLLQSGR-LDVDGIFTTTLPLDEAAKGYATARARSGEE
MUL_2962|M.ulcerans_Agy99           IAPVQRTWSELIPLLESGR-LDVDGIFTTSLPLDEAAKGYSIAGSRSGND
MAB_0526c|M.abscessus_ATCC_199      LAYEPAEFSETLRRIAHGEIDVAP-LVTGEVGLEDVGSAFADLGDP-ERH
                                    ::            :   .       .*  .  ::.  .:          

Mflv_4106|M.gilvum_PYR-GCK          VKIAIEAR------------------------------------------
Mvan_2240|M.vanbaalenii_PYR-1       IKIAIVA-------------------------------------------
TH_0280|M.thermoresistible__bu      IKIAIVG-------------------------------------------
MSMEG_2564|M.smegmatis_MC2_155      VKIVVAR-------------------------------------------
MMAR_0400|M.marinum_M               VKIAITA-------------------------------------------
MAV_5122|M.avium_104                IKIAIAG-------------------------------------------
Mb1929|M.bovis_AF2122/97            LKVLLTP-------------------------------------------
Rv1895|M.tuberculosis_H37Rv         LRFCLRPDSRDVLGAHETVDLYVHVRRCQSVADLQLEGAADGVDGPSMLN
MUL_2962|M.ulcerans_Agy99           VKVLLKV-------------------------------------------
MAB_0526c|M.abscessus_ATCC_199      CKILVVP-------------------------------------------
                                     :. :