For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VWSYRLVAPFIFEKADVPQRCPESLGDGQVLLRFLAAGICGSDLPGYRGAKGRLAGDTGACAAEMDGFPI HEIAGEVIASRHPAHRPGDRVVGWASGFDGLMEQVIADGDGLVAYHGSLSPAHAVALQPLACVLYAVEQL PDLTGRHVAVLGQGSIGLLFSHAAKAAGAAHVTGVDPVDRDDVGPSFGVDTVVRATSDRWVSRLAPDAKP DIVIEAVGHQVATLSHAVEAAAFGGTVFYFGVPDDDCYPISMRTMLRNNLTLKSGVTIERRRVLAKADAF VQEHPGLLERYLTHTFGVDEAPAAFELASRPVPGRIKIAIVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2240 | - | - | 100% (322) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2879 | - | 4e-13 | 25.07% (347) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0490 | - | 6e-08 | 27.89% (190) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1557 | adh | 2e-09 | 28.57% (266) | alcohol dehydrogenase adh |
| M. gilvum PYR-GCK | Mflv_4106 | - | 1e-150 | 79.81% (322) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv1895 | - | 3e-10 | 29.24% (277) | dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0526c | - | 1e-10 | 27.08% (240) | hypothetical protein MAB_0526c |
| M. marinum M | MMAR_0400 | - | 1e-133 | 71.12% (322) | dehydrogenase |
| M. avium 104 | MAV_5122 | - | 1e-133 | 73.12% (320) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_2564 | - | 1e-139 | 74.38% (320) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_0280 | - | 1e-143 | 76.01% (321) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_2962 | - | 3e-10 | 25.08% (323) | dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2240|M.vanbaalenii_PYR-1 MWSYRLVAPFIFEKAD---VPQRCPESLGDGQVLLRFLAAGICGSDLPGY
Mflv_4106|M.gilvum_PYR-GCK MWSYRLVAPYTFERTE---QPQRSPESLAENQVLLRFLAGGICGSDLPGF
TH_0280|M.thermoresistible__bu MWAYRLTAPYRFDRIE---VPEPDPDGLRDGQVLLRFLAAGVCGSDLPGF
MSMEG_2564|M.smegmatis_MC2_155 MWSYRLVAPYVFERSD---LRAPSPDALTDGQVLLSFSAAGICGSDIPGF
MMAR_0400|M.marinum_M MWSYRIIAPYLFERTS---IADKTPECLAEGQVLLRFQAAGVCGSDLPAF
MAV_5122|M.avium_104 MWCYRIVAPYRFEPTA---IDDKTPECLADGQVLLRFSAAGVCGSDLPAF
Rv1895|M.tuberculosis_H37Rv MRAVVIDGAGSVRVNT---QPD--PALPGPDGVVVAVTAAGICGSDLHFY
MUL_2962|M.ulcerans_Agy99 MRTVVIDGPGSIRVDN---RPD--PALPGSDGVIVVVSAAGICGSDLHFY
Mb1557|M.bovis_AF2122/97 MSDGAVVRALVLEAPRRLVVRQYRLPRIGDDDALVRVEACGLCGTDHEQY
MAB_0526c|M.abscessus_ATCC_199 MRASVLRNGSMVYRDD------VPSPTPGEGQVLVKVSACGICGSDLHFA
* : . . .:: . * *:**:*
Mvan_2240|M.vanbaalenii_PYR-1 RGAKGRLA------GDTGACAAEMDG--------------FPIHEIAGEV
Mflv_4106|M.gilvum_PYR-GCK RGARGRLA------FDTGRQAAEKDG--------------FPIHEVVGEV
TH_0280|M.thermoresistible__bu RGTQGRLP------GDTGVSTCEIPG--------------FPIHEIAGEV
MSMEG_2564|M.smegmatis_MC2_155 RGTQGKLP------GDTGASAAQMPG--------------FPIHEIAGEV
MMAR_0400|M.marinum_M RGARGHLP------GDDGHSAAAKDG--------------FPIHEVAGEV
MAV_5122|M.avium_104 RGARGRLP------GDDGRSGPEKDG--------------FPIHEVAGEV
Rv1895|M.tuberculosis_H37Rv EGEYPFTEP--VALGHEAVGTIVEAGPQVRTVG---VGDLVMVSSVAGCG
MUL_2962|M.ulcerans_Agy99 EGEYPLAEP--VALGHEAVGTVVEKGPDVHTVE---VGDQVMVSSVAGCG
Mb1557|M.bovis_AF2122/97 TGELAGGFA--FVPGHETVGTIAAIGPRAEQRWGVSAGDRVAVEVFQSCR
MAB_0526c|M.abscessus_ATCC_199 KHGARAIELSKQMVGMPSLTDGVDLS-----------TDVFMGHEFAAEV
. . . .
Mvan_2240|M.vanbaalenii_PYR-1 IASRHPAHRPGD----RVVG---WASGFDG-----------LMEQVIADG
Mflv_4106|M.gilvum_PYR-GCK LASRHLAHTPGD----RVVG---WASGFDG-----------LAEEVVADG
TH_0280|M.thermoresistible__bu IASRHPQHHPGD----RVVG---WASGFDG-----------LQARVTADG
MSMEG_2564|M.smegmatis_MC2_155 LASRHPDHRVGD----HVVG---WASGFDG-----------LMEQVIADG
MMAR_0400|M.marinum_M IASRHRAHHQGD----RVVG---WASGFDG-----------LMQRVIADG
MAV_5122|M.avium_104 IASRHPAHRPGD----RVVG---WASGFDG-----------LMERVVSDG
Rv1895|M.tuberculosis_H37Rv VCPGCETHDPVM----CFSGPMIFGAGVLGGAQA-------DLLAVPAAD
MUL_2962|M.ulcerans_Agy99 ACAGCATRDPAM----CVSGPQIFGSGALGGAQA-------DLLAVPATD
Mb1557|M.bovis_AF2122/97 QCANCRGGEYRR----CVRHGLADMYGFIPVDREPGLWGGYAEYQYLAPD
MAB_0526c|M.abscessus_ATCC_199 IEAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTTLGG-YAEQMLLSA
. *
Mvan_2240|M.vanbaalenii_PYR-1 DGLVAYHGSLSPAHAVALQP-LACVLYAVEQLPDLTGRHVAVLGQGSIGL
Mflv_4106|M.gilvum_PYR-GCK EGLASYDPSLDPAHAVALQP-LACVLYAVEQMPDLAGRHVAILGQGSIGL
TH_0280|M.thermoresistible__bu DGLARYDAALEPRHAVALQP-LACVLYAVEQLGDLTGRRVAVIGQGSIGL
MSMEG_2564|M.smegmatis_MC2_155 DGLVSYDPALPPRLAVGLQP-LACVLCAVEQLPDLDGRHVAVIGQGSIGL
MMAR_0400|M.marinum_M DGLAPYDPGLTPTQAVGLQP-LACVLYACAQLPDLAGRHVAVIGQGSIGL
MAV_5122|M.avium_104 DGLAPYDPALSPAQAVGLQP-LACVLYACEQL-ELAGKHVAIIGQGSIGL
Rv1895|M.tuberculosis_H37Rv FQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGL
MUL_2962|M.ulcerans_Agy99 FQVLKIPAAITTEQALLLTDNLATGWAAARRADIPFGATVAVIGLGAVGL
Mb1557|M.bovis_AF2122/97 SMVLRVAGDLSPEVATLFNPLGAGIRWGVTIPETKPGDVVAVLGPGIRGL
MAB_0526c|M.abscessus_ATCC_199 PLLLPIPNGLDPRHAALTEP-MAVGLHAVNKSAIQPGTGAIVIGCGPVGI
: : . * * . * . ::* * *:
Mvan_2240|M.vanbaalenii_PYR-1 LFSHAAKAAGAAHVTGVDP----VDRDDVGPSFGVDTVVRATSDRWVSRL
Mflv_4106|M.gilvum_PYR-GCK LFSYVAKAAGAAHVTGVDP----VDRSAVGAAFGVDTVVRATSDRWVSHL
TH_0280|M.thermoresistible__bu LFSYVAKAAGAAHVTGVDP----VDRELVGKEFGVDTVVRATSDRWIRHL
MSMEG_2564|M.smegmatis_MC2_155 LFSYVAKALGAARVTGVDP----LDRSAIAARFGIDTPVRATSDRWVTHL
MMAR_0400|M.marinum_M LFSHAAKVAGARRVTGVDP----IDRENLSATFGVDDAVRATSDRWVSQL
MAV_5122|M.avium_104 LFSYVAKAAGARRVTGVDP----IDRRDVARAFGVDDPVRATSDRWVSQL
Rv1895|M.tuberculosis_H37Rv CALRSAFIHGAATVFAVDR----VKGRLQRAATWGATPIPSPAAETILAA
MUL_2962|M.ulcerans_Agy99 CAVRSALAQGAATVFAVDR----VQGRLQRAAEWGATAVASPAAEAIVAA
Mb1557|M.bovis_AF2122/97 CAAAAAKGAGAGFVMVTGLGPRDADRLALAAQFGADLAVDVAIDDPVAAL
MAB_0526c|M.abscessus_ATCC_199 AVIAALHNLGIEPIVASDYS---SARRDLAQRMGAHQVVDPKIEPTFHAW
* : . : .
Mvan_2240|M.vanbaalenii_PYR-1 APDAK--PDIVIEAVGHQVATLSHAVEAAAFGGTVFYFGVP--DDDCYPI
Mflv_4106|M.gilvum_PYR-GCK GADDR--PDVVIEAVGHQVATLTHAVEAAAFGGFVFYFGVP--DDDWYPI
TH_0280|M.thermoresistible__bu GADDR--ADVVIEAVGHQVATLNHAIEATAFGGTVFYFGVP--DDDSYPI
MSMEG_2564|M.smegmatis_MC2_155 DPDDR--ADVVIEAVGHQVATLNHALTAAAFGGTVFYFGVP--DDDSYPI
MMAR_0400|M.marinum_M GAGDR--ADIVIEAVGHQVATLGHAIDAAAPGGTVFYFGVA--DDDAYPI
MAV_5122|M.avium_104 DPADR--ADVVIEAVGHQVATLAHAIDAAAPGGTVFYFGVA--DDDTYPI
Rv1895|M.tuberculosis_H37Rv TRGRG--ADSVIDAVGTDAS-MSDALNAVRPGGTVSVVGVH--DLQPFPV
MUL_2962|M.ulcerans_Agy99 TSGRG--ADSVIDAVDTDAS-MTDALNAVRAGGTVSVVGVH--DLQPFPL
Mb1557|M.bovis_AF2122/97 TEQTGGLADVVVDVTAKAPAAFAQAIALARPAGTVVVAGTRGVGSGAPGF
MAB_0526c|M.abscessus_ATCC_199 SRIGAG-APVIFEAVG-VPGILNEVLRDAPRSARVVVVGVC---MEPDAI
. :.:.. . : ..: . .. * *. .
Mvan_2240|M.vanbaalenii_PYR-1 SMRTMLRNNLTLKSGVTIERRRVLAKADAFVQEHPGLLERYLTHTFGVDE
Mflv_4106|M.gilvum_PYR-GCK SMRTMLRNNLTLKAGVTLERRRVLRCADEFAAAHPGLLDRYLTHTFGVDD
TH_0280|M.thermoresistible__bu NMRAMLRNNLTLKSGVTLDRRRMLARADAFAREHSDLLTRYLTHTFGADE
MSMEG_2564|M.smegmatis_MC2_155 SMRTMLRNNLTLKSGVTTDRQRVLRRADTFAREHPHLLPGYVTHTFGVDD
MMAR_0400|M.marinum_M SMRTMLRNNLTLKSGVTQDRRRMLELAGKFAAEHPELLSGYLTHNFDVED
MAV_5122|M.avium_104 SMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDE
Rv1895|M.tuberculosis_H37Rv PALTCLLRSITLRMTMAPVQRTWPELIPLLQSGR-LDVDGIFTTTLPLDE
MUL_2962|M.ulcerans_Agy99 PALTCLLRSITLRLTIAPVQRTWSELIPLLESGR-LDVDGIFTTSLPLDE
Mb1557|M.bovis_AF2122/97 SPDVVVFKELRVLGALGVDATAYRAALDLLVSGR-YPFASLPRRCVRLEG
MAB_0526c|M.abscessus_ATCC_199 TPYFGIAKEVAVQFVLAYEPAEFSETLRRIAHGE-IDVAPLVTGEVGLED
: ..: : : : . . . :
Mvan_2240|M.vanbaalenii_PYR-1 APAAFELASRPVPGRIKIAIVA----------------------------
Mflv_4106|M.gilvum_PYR-GCK VQQAFELAARPVPGRVKIAIEAR---------------------------
TH_0280|M.thermoresistible__bu AQAAFELACRPAPERIKIAIVG----------------------------
MSMEG_2564|M.smegmatis_MC2_155 VQAAFELACRPVPDRVKIVVAR----------------------------
MMAR_0400|M.marinum_M VQAAFELACRPVPERVKIAITA----------------------------
MAV_5122|M.avium_104 VQDAFELACRPVADRIKIAIAG----------------------------
Rv1895|M.tuberculosis_H37Rv AAKGYATARARSGEELRFCLRPDSRDVLGAHETVDLYVHVRRCQSVADLQ
MUL_2962|M.ulcerans_Agy99 AAKGYSIAGSRSGNDVKVLLKV----------------------------
Mb1557|M.bovis_AF2122/97 AEDLLATMAGERDGVPPIHGVLTP--------------------------
MAB_0526c|M.abscessus_ATCC_199 VGSAFADLGDP-ERHCKILVVP----------------------------
. .
Mvan_2240|M.vanbaalenii_PYR-1 ---------------
Mflv_4106|M.gilvum_PYR-GCK ---------------
TH_0280|M.thermoresistible__bu ---------------
MSMEG_2564|M.smegmatis_MC2_155 ---------------
MMAR_0400|M.marinum_M ---------------
MAV_5122|M.avium_104 ---------------
Rv1895|M.tuberculosis_H37Rv LEGAADGVDGPSMLN
MUL_2962|M.ulcerans_Agy99 ---------------
Mb1557|M.bovis_AF2122/97 ---------------
MAB_0526c|M.abscessus_ATCC_199 ---------------