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WSYRLVAPYTFERTEQPQRSPESLAENQVLLRFLAGGICGSDLPGFRGARGRLAFDTGRQAAEKDGFPIH EVVGEVLASRHLAHTPGDRVVGWASGFDGLAEEVVADGEGLASYDPSLDPAHAVALQPLACVLYAVEQMP DLAGRHVAILGQGSIGLLFSYVAKAAGAAHVTGVDPVDRSAVGAAFGVDTVVRATSDRWVSHLGADDRPD VVIEAVGHQVATLTHAVEAAAFGGFVFYFGVPDDDWYPISMRTMLRNNLTLKAGVTLERRRVLRCADEFA AAHPGLLDRYLTHTFGVDDVQQAFELAARPVPGRVKIAIEAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4106 | - | - | 100% (323) | alcohol dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4626 | - | 2e-09 | 35.38% (130) | alcohol dehydrogenase |
| M. gilvum PYR-GCK | Mflv_3479 | - | 6e-09 | 24.84% (322) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1929 | - | 1e-06 | 33.81% (139) | dehydrogenase |
| M. tuberculosis H37Rv | Rv1895 | - | 1e-07 | 28.57% (280) | dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0526c | - | 3e-09 | 25.82% (244) | hypothetical protein MAB_0526c |
| M. marinum M | MMAR_0400 | - | 1e-135 | 73.29% (322) | dehydrogenase |
| M. avium 104 | MAV_5122 | - | 1e-135 | 75.00% (320) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_2564 | - | 1e-137 | 74.38% (320) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_0280 | - | 1e-139 | 74.38% (320) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_2962 | - | 7e-08 | 27.58% (330) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2240 | - | 1e-150 | 79.81% (322) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4106|M.gilvum_PYR-GCK MWSYRLVAPYTFERTEQPQRSPESLAENQVLLRFLAGGICGSDLPGFRGA
Mvan_2240|M.vanbaalenii_PYR-1 MWSYRLVAPFIFEKADVPQRCPESLGDGQVLLRFLAAGICGSDLPGYRGA
TH_0280|M.thermoresistible__bu MWAYRLTAPYRFDRIEVPEPDPDGLRDGQVLLRFLAAGVCGSDLPGFRGT
MSMEG_2564|M.smegmatis_MC2_155 MWSYRLVAPYVFERSDLRAPSPDALTDGQVLLSFSAAGICGSDIPGFRGT
MMAR_0400|M.marinum_M MWSYRIIAPYLFERTSIADKTPECLAEGQVLLRFQAAGVCGSDLPAFRGA
MAV_5122|M.avium_104 MWCYRIVAPYRFEPTAIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGA
Mb1929|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv MRAVVIDGAGSVRVNTQPD--PALPGPDGVVVAVTAAGICGSDLHFYEGE
MUL_2962|M.ulcerans_Agy99 MRTVVIDGPGSIRVDNRPD--PALPGSDGVIVVVSAAGICGSDLHFYEGE
MAB_0526c|M.abscessus_ATCC_199 MRASVLRNGSMVYRDDVPS---PTPGEGQVLVKVSACGICGSDLHFAKHG
Mflv_4106|M.gilvum_PYR-GCK RGRLA---------------FDTGRQAAEKDGFPIHEVVGEVLASRHLAH
Mvan_2240|M.vanbaalenii_PYR-1 KGRLA---------------GDTGACAAEMDGFPIHEIAGEVIASRHPAH
TH_0280|M.thermoresistible__bu QGRLP---------------GDTGVSTCEIPGFPIHEIAGEVIASRHPQH
MSMEG_2564|M.smegmatis_MC2_155 QGKLP---------------GDTGASAAQMPGFPIHEIAGEVLASRHPDH
MMAR_0400|M.marinum_M RGHLP---------------GDDGHSAAAKDGFPIHEVAGEVIASRHRAH
MAV_5122|M.avium_104 RGRLP---------------GDDGRSGPEKDGFPIHEVAGEVIASRHPAH
Mb1929|M.bovis_AF2122/97 --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv YPFTEPVALGHEAVGTIVEAGPQVRTVGVGDLVMVSSVAGCGVCPGCETH
MUL_2962|M.ulcerans_Agy99 YPLAEPVALGHEAVGTVVEKGPDVHTVEVGDQVMVSSVAGCGACAGCATR
MAB_0526c|M.abscessus_ATCC_199 ARAIELSKQMVG------MPSLTDGVDLSTDVFMGHEFAAEVIEAGPRTQ
Mflv_4106|M.gilvum_PYR-GCK T-----PGDRVVG--WASGFD----------GLAEEVVADGEGLASYDPS
Mvan_2240|M.vanbaalenii_PYR-1 R-----PGDRVVG--WASGFD----------GLMEQVIADGDGLVAYHGS
TH_0280|M.thermoresistible__bu H-----PGDRVVG--WASGFD----------GLQARVTADGDGLARYDAA
MSMEG_2564|M.smegmatis_MC2_155 R-----VGDHVVG--WASGFD----------GLMEQVIADGDGLVSYDPA
MMAR_0400|M.marinum_M H-----QGDRVVG--WASGFD----------GLMQRVIADGDGLAPYDPG
MAV_5122|M.avium_104 R-----PGDRVVG--WASGFD----------GLMERVVSDGDGLAPYDPA
Mb1929|M.bovis_AF2122/97 ---------MIFGAGVLGGAQ----------ADLLAVPAADFQVLKIPEG
Rv1895|M.tuberculosis_H37Rv DPVMCFSGPMIFGAGVLGGAQ----------ADLLAVPAADFQVLKIPEG
MUL_2962|M.ulcerans_Agy99 DPAMCVSGPQIFGSGALGGAQ----------ADLLAVPATDFQVLKIPAA
MAB_0526c|M.abscessus_ATCC_199 APASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLLSAPLLLPIPNG
: * : . : : .
Mflv_4106|M.gilvum_PYR-GCK LDPAHAVALQP-LACVLYAVEQMPDLAGRHVAILGQGSIGLLFSYVAKAA
Mvan_2240|M.vanbaalenii_PYR-1 LSPAHAVALQP-LACVLYAVEQLPDLTGRHVAVLGQGSIGLLFSHAAKAA
TH_0280|M.thermoresistible__bu LEPRHAVALQP-LACVLYAVEQLGDLTGRRVAVIGQGSIGLLFSYVAKAA
MSMEG_2564|M.smegmatis_MC2_155 LPPRLAVGLQP-LACVLCAVEQLPDLDGRHVAVIGQGSIGLLFSYVAKAL
MMAR_0400|M.marinum_M LTPTQAVGLQP-LACVLYACAQLPDLAGRHVAVIGQGSIGLLFSHAAKVA
MAV_5122|M.avium_104 LSPAQAVGLQP-LACVLYACEQL-ELAGKHVAIIGQGSIGLLFSYVAKAA
Mb1929|M.bovis_AF2122/97 ITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFIH
Rv1895|M.tuberculosis_H37Rv ITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFIH
MUL_2962|M.ulcerans_Agy99 ITTEQALLLTDNLATGWAAARRADIPFGATVAVIGLGAVGLCAVRSALAQ
MAB_0526c|M.abscessus_ATCC_199 LDPRHAALTEP-MAVGLHAVNKSAIQPGTGAIVIGCGPVGIAVIAALHNL
: . * :* * : * . ::* *.:*:
Mflv_4106|M.gilvum_PYR-GCK GAAHVTGVDPVDRSAVGAAFGVDTVVRATSDRWVSHLGA--DDRPDVVIE
Mvan_2240|M.vanbaalenii_PYR-1 GAAHVTGVDPVDRDDVGPSFGVDTVVRATSDRWVSRLAP--DAKPDIVIE
TH_0280|M.thermoresistible__bu GAAHVTGVDPVDRELVGKEFGVDTVVRATSDRWIRHLGA--DDRADVVIE
MSMEG_2564|M.smegmatis_MC2_155 GAARVTGVDPLDRSAIAARFGIDTPVRATSDRWVTHLDP--DDRADVVIE
MMAR_0400|M.marinum_M GARRVTGVDPIDRENLSATFGVDDAVRATSDRWVSQLGA--GDRADIVIE
MAV_5122|M.avium_104 GARRVTGVDPIDRRDVARAFGVDDPVRATSDRWVSQLDP--ADRADVVIE
Mb1929|M.bovis_AF2122/97 GAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR--GRGADSVID
Rv1895|M.tuberculosis_H37Rv GAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR--GRGADSVID
MUL_2962|M.ulcerans_Agy99 GAATVFAVDRVQGRLQRAAEWGATAVASPAAEAIVAATS--GRGADSVID
MAB_0526c|M.abscessus_ATCC_199 GIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTFHAWSRIGAGAPVIFE
* : . * . : . . . :::
Mflv_4106|M.gilvum_PYR-GCK AVGHQVATLTHAVEAAAFGGFVFYFGVPDDDWYPISMRTMLRNNLTLKAG
Mvan_2240|M.vanbaalenii_PYR-1 AVGHQVATLSHAVEAAAFGGTVFYFGVPDDDCYPISMRTMLRNNLTLKSG
TH_0280|M.thermoresistible__bu AVGHQVATLNHAIEATAFGGTVFYFGVPDDDSYPINMRAMLRNNLTLKSG
MSMEG_2564|M.smegmatis_MC2_155 AVGHQVATLNHALTAAAFGGTVFYFGVPDDDSYPISMRTMLRNNLTLKSG
MMAR_0400|M.marinum_M AVGHQVATLGHAIDAAAPGGTVFYFGVADDDAYPISMRTMLRNNLTLKSG
MAV_5122|M.avium_104 AVGHQVATLAHAIDAAAPGGTVFYFGVADDDTYPISMRTMLRNNLTLKSG
Mb1929|M.bovis_AF2122/97 AVGTDAS-MSDALNAVRPGGTVSVVGVHDLQPFPLPALTCLLRSITLRMT
Rv1895|M.tuberculosis_H37Rv AVGTDAS-MSDALNAVRPGGTVSVVGVHDLQPFPVPALTCLLRSITLRMT
MUL_2962|M.ulcerans_Agy99 AVDTDAS-MTDALNAVRAGGTVSVVGVHDLQPFPLPALTCLLRSITLRLT
MAB_0526c|M.abscessus_ATCC_199 AVG-VPGILNEVLRDAPRSARVVVVGVC-MEPDAITPYFGIAKEVAVQFV
**. . : ..: . .. * .** : .: : ..::::
Mflv_4106|M.gilvum_PYR-GCK VTLERRRVLRCADEFAAAHPGLLDRYLTHTFGVDDVQQAFELAARPVPGR
Mvan_2240|M.vanbaalenii_PYR-1 VTIERRRVLAKADAFVQEHPGLLERYLTHTFGVDEAPAAFELASRPVPGR
TH_0280|M.thermoresistible__bu VTLDRRRMLARADAFAREHSDLLTRYLTHTFGADEAQAAFELACRPAPER
MSMEG_2564|M.smegmatis_MC2_155 VTTDRQRVLRRADTFAREHPHLLPGYVTHTFGVDDVQAAFELACRPVPDR
MMAR_0400|M.marinum_M VTQDRRRMLELAGKFAAEHPELLSGYLTHNFDVEDVQAAFELACRPVPER
MAV_5122|M.avium_104 VTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDEVQDAFELACRPVADR
Mb1929|M.bovis_AF2122/97 MAPVQRTWPELIPLLQSGR-LDVDGIFTTTLPLDEAAKGYATARARSGEE
Rv1895|M.tuberculosis_H37Rv MAPVQRTWPELIPLLQSGR-LDVDGIFTTTLPLDEAAKGYATARARSGEE
MUL_2962|M.ulcerans_Agy99 IAPVQRTWSELIPLLESGR-LDVDGIFTTSLPLDEAAKGYSIAGSRSGND
MAB_0526c|M.abscessus_ATCC_199 LAYEPAEFSETLRRIAHGEIDVAP-LVTGEVGLEDVGSAFADLGDP-ERH
:: : . .* . ::. .:
Mflv_4106|M.gilvum_PYR-GCK VKIAIEAR------------------------------------------
Mvan_2240|M.vanbaalenii_PYR-1 IKIAIVA-------------------------------------------
TH_0280|M.thermoresistible__bu IKIAIVG-------------------------------------------
MSMEG_2564|M.smegmatis_MC2_155 VKIVVAR-------------------------------------------
MMAR_0400|M.marinum_M VKIAITA-------------------------------------------
MAV_5122|M.avium_104 IKIAIAG-------------------------------------------
Mb1929|M.bovis_AF2122/97 LKVLLTP-------------------------------------------
Rv1895|M.tuberculosis_H37Rv LRFCLRPDSRDVLGAHETVDLYVHVRRCQSVADLQLEGAADGVDGPSMLN
MUL_2962|M.ulcerans_Agy99 VKVLLKV-------------------------------------------
MAB_0526c|M.abscessus_ATCC_199 CKILVVP-------------------------------------------
:. :