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AVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWALFLACYATGGWE PGLAGLQALQRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPG TATRVGAGGGEETVNAADLRIGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGT VNGTGALRIRVDRLARDSVVARIATLVEQASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETL QRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPE LAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTVGEFTAHPGCRVTARVDGHVIA VGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAAAISAATKLTGA KPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVGIAM GSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVARH EGSTIIVGLNGLRLLRHTAWRRAAGTAHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3743c | ctpJ | - | 100% (660) | PROBABLE CATION TRANSPORTER P-TYPE ATPASE CTPJ |
| M. tuberculosis H37Rv | Rv1469 | ctpD | 0.0 | 55.54% (650) | cation transporter P-type ATPase D |
| M. tuberculosis H37Rv | Rv1992c | ctpG | 4e-92 | 35.83% (628) | metal cation transporter P-type ATPase G CtpG |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3769c | ctpJ | 0.0 | 100.00% (660) | putative cation transporter P-type atpase ctpJ |
| M. gilvum PYR-GCK | Mflv_2822 | - | 1e-109 | 38.01% (642) | heavy metal translocating P-type ATPase |
| M. leprae Br4923 | MLBr_00747 | ctpC | 2e-73 | 31.71% (574) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_4853c | - | 1e-100 | 37.16% (627) | cation-transporting ATPase G |
| M. marinum M | MMAR_2275 | ctpD | 0.0 | 56.79% (648) | cation transporter p-type ATPase D CtpD |
| M. avium 104 | MAV_5246 | - | 3e-82 | 35.31% (657) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5403 | cadA | 0.0 | 59.01% (627) | cadmium-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_2531 | - | 3e-87 | 36.86% (643) | PUTATIVE copper-translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_1477 | ctpD | 0.0 | 56.19% (646) | cation transporter p-type ATPase D CtpD |
| M. vanbaalenii PYR-1 | Mvan_3729 | - | 0.0 | 61.19% (639) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5246|M.avium_104 --------------------------------------------------
TH_2531|M.thermoresistible__bu --------------------------------------------------
MLBr_00747|M.leprae_Br4923 --------------------------------------------------
Rv3743c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3769c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2275|M.marinum_M --------------------------------------------------
MUL_1477|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALD
MAB_4853c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_5246|M.avium_104 --------------------------------------------------
TH_2531|M.thermoresistible__bu --------------------------------------------------
MLBr_00747|M.leprae_Br4923 ------------------------------------------------MT
Rv3743c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3769c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2275|M.marinum_M --------------------------------------------------
MUL_1477|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK LTDLLPDSDERCADRLTRGLVDDGIIEQAHVIDGDTPKPRLCVHYDAEAA
MAB_4853c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_5246|M.avium_104 --MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDG
TH_2531|M.thermoresistible__bu --MVGPAHHG--------TVAADGRAQHLTGR---------DHHRHGHG-
MLBr_00747|M.leprae_Br4923 LAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCN
Rv3743c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3769c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2275|M.marinum_M --------------------------------------------------
MUL_1477|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK SATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTALVDTLSTIPGV
MAB_4853c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_5246|M.avium_104 VTATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPRDDPEL
TH_2531|M.thermoresistible__bu -----------------------------DHAGHVAEFRR--------LF
MLBr_00747|M.leprae_Br4923 ---------------------GVRVVHAYPRTGSVVVWYSPRCCDRQSIL
Rv3743c|M.tuberculosis_H37Rv -------------------------MAVRELSPARCTSASPLVLARR---
Mb3769c|M.bovis_AF2122/97 -------------------------MAVRELSPARCTSASPLVLARR---
MMAR_2275|M.marinum_M -----------------------MTLTAFEVSAAEASSDRPDRIPSTSVR
MUL_1477|M.ulcerans_Agy99 -----------------------MTLTAFEVSAAEASSDRSDRIPSTSVR
MSMEG_5403|M.smegmatis_MC2_155 -------------------------MTALYPAVEPAPAARPARPRSG---
Mvan_3729|M.vanbaalenii_PYR-1 ------------------MRVCAGIVVRVSADLQAADWERTTATGEEVRG
Mflv_2822|M.gilvum_PYR-GCK VAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHDGD
MAB_4853c|M.abscessus_ATCC_199 -------------------------------MSDACGCGHDEPATGDEVD
MAV_5246|M.avium_104 ASLRRRLVTAIALAG----PVIAVAMIPALQFQHWHWAALALTAPVVGWC
TH_2531|M.thermoresistible__bu WVMLLLAVPTVAFSG----MFAMILGYQVPRVPGAQWVSPVLGTVMYVWG
MLBr_00747|M.leprae_Br4923 AAISGAAHVAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFA
Rv3743c|M.tuberculosis_H37Rv -----TKLFALS--------EMRWAALALGLFSAG-LLTQLCGAPQWVRW
Mb3769c|M.bovis_AF2122/97 -----TKLFALS--------EMRWAALALGLFSAG-LLTQLCGAPQWVRW
MMAR_2275|M.marinum_M PLTWRAALWSVM--------SVRWAGIALALFLTG-LVAQLNGAAEPVWW
MUL_1477|M.ulcerans_Agy99 PLTWRAALWSVM--------SVRWAGIALALFLTG-LVAQLNGAAEPVWW
MSMEG_5403|M.smegmatis_MC2_155 -----GWLWTVP--------SVRWAAAALALFLTG-LAAQLLGAPQAVVW
Mvan_3729|M.vanbaalenii_PYR-1 WRAPRSSAWSLP--------EVRWALIATVLFVVG-GLAQLVGAPPWLYW
Mflv_2822|M.gilvum_PYR-GCK GADHQHGHGGISGER----TELVFAGLAGALLLTGWLLAAFADTPRSAEV
MAB_4853c|M.abscessus_ATCC_199 GEREPERLWEVS--------ELRFAAVAGVVLLAGYVVG-WTGGSHPVEI
.
MAV_5246|M.avium_104 GRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRH
TH_2531|M.thermoresistible__bu GRPFLTGAISEIRSRTPGMMLLIGLALTVAFLSS----------------
MLBr_00747|M.leprae_Br4923 RPLLLPTTSRLVASGVTIFTGYPFLRGALRFGKTG---------------
Rv3743c|M.tuberculosis_H37Rv ALFLACYATGGWEPGLAGLQALQRRTLDVDLLMVV---------------
Mb3769c|M.bovis_AF2122/97 ALFLACYATGGWEPGLAGLQALQRRTLDVDLLMVV---------------
MMAR_2275|M.marinum_M TLYLACYLAGGWGSAWAGAQALRNRALDVDLLMIV---------------
MUL_1477|M.ulcerans_Agy99 TLYLACYLAGGWGSAWAGAQALRNRALDVDLLMIV---------------
MSMEG_5403|M.smegmatis_MC2_155 TLYLACYVVGGWEPAWVGVRALRNRTLDVDLLMIV---------------
Mvan_3729|M.vanbaalenii_PYR-1 TLYLACYVTGGWEPGWAGLQALRDKTLDVDLLMVA---------------
Mflv_2822|M.gilvum_PYR-GCK VVYGLAFFFGAFFTVQEAFASVRQGRFEIDFLMLV---------------
MAB_4853c|M.abscessus_ATCC_199 GLYAAALAIGAYTFVPSTLRRLARGKIGVGTLMTI---------------
MAV_5246|M.avium_104 DFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAA
TH_2531|M.thermoresistible__bu -------WGASLGVLDHRLEFWWELALLIVIMLLG-HWIELRSLARTTSA
MLBr_00747|M.leprae_Br4923 -----TDALVSAATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRA
Rv3743c|M.tuberculosis_H37Rv ------------AAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADS
Mb3769c|M.bovis_AF2122/97 ------------AAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADS
MMAR_2275|M.marinum_M ------------AAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADS
MUL_1477|M.ulcerans_Agy99 ------------AAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADS
MSMEG_5403|M.smegmatis_MC2_155 ------------AAIGAATIGQVFDGALLIVIFATSGALEDVATTRTERS
Mvan_3729|M.vanbaalenii_PYR-1 ------------AAIGAAAIGQVFDGALLIVIFATSGALEAVATKRTEDS
Mflv_2822|M.gilvum_PYR-GCK ------------SAAGAAALGEVAEGALLLFLFSVGHALEGYAMGRARRA
MAB_4853c|M.abscessus_ATCC_199 ------------AAIGAVILGEVGEAAMLAFLFSISEGLEEYALARTRRG
. . : :. :: : .
MAV_5246|M.avium_104 LRALLALGAKDVAV-LRAG----AETRIPIERLAVGDEFVVRPGERIATD
TH_2531|M.thermoresistible__bu LDSLAALLPDTAER-VEQGPDGETVTVVAPADLRVGDTVIVRPGAGIPAD
MLBr_00747|M.leprae_Br4923 ISALLSGTQDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVD
Rv3743c|M.tuberculosis_H37Rv VRGLMGLAPGTAT----RVGAGGGEETVNAADLRIGDIVLVRPGERISAD
Mb3769c|M.bovis_AF2122/97 VRGLMGLAPGTAT----RVGAGGGEETVNAADLRIGDIVLVRPGERISAD
MMAR_2275|M.marinum_M VKGLLDLAPEQAT----VFDVDGNEQVVAASELVVGDRVVVRPGERIPAD
MUL_1477|M.ulcerans_Agy99 VKGLLDLAPEQAT----VFDVDGNEQVVAASELVVGDRVVVRPGERIPAD
MSMEG_5403|M.smegmatis_MC2_155 VRGLLDLAPEHAT----LLG-DGSQRVVAAADLRPGDVIVVRPGERISAD
Mvan_3729|M.vanbaalenii_PYR-1 VRGLLDLAPDTAT----RLTDSGAEEVVDTAVLDVGDVLMIRPGERIGGD
Mflv_2822|M.gilvum_PYR-GCK IEALAELAPKTALV---RRGGTGDTVEVSVADLRIGDIVVVRPNMRLAAD
MAB_4853c|M.abscessus_ATCC_199 LRALLSLAPEEATV---LRDGT--ETTITATELQVGDTMLVRPGERVATD
: .* . : : ** .::: : *
MAV_5246|M.avium_104 GIVVAGSSAVDAAMLTGESVPVEVGVG----------------DGVTGGT
TH_2531|M.thermoresistible__bu GRIIDGVADVDESMVTGESVPVRRGVG----------------DRVVAAT
MLBr_00747|M.leprae_Br4923 GEVIDGEAVVNQSAITGENLPVSVMAG----------------SHVHAGS
Rv3743c|M.tuberculosis_H37Rv ATVLAGGSEVDQATVTGEPLPVDKSIG----------------DQVFAGT
Mb3769c|M.bovis_AF2122/97 ATVLAGGSEVDQATVTGEPLPVDKSIG----------------DQVFAGT
MMAR_2275|M.marinum_M GAVLSGCSEVDQCSITGESMPAAKGRG----------------DEVFAGT
MUL_1477|M.ulcerans_Agy99 GAVLSGCSEVDQCSIAGESMPAAKGRG----------------DEVFAGT
MSMEG_5403|M.smegmatis_MC2_155 GTVIGGASEVDQSSITGEPLPAAKDVG----------------DDVFAGT
Mvan_3729|M.vanbaalenii_PYR-1 GTVVDGASEVDQATITGEPLPVDKATG----------------DEVFAGT
Mflv_2822|M.gilvum_PYR-GCK GFVVAGSSSIDQAPVTGESVPVDKIPVPDVAAAAASPELIDAASRVFAGT
MAB_4853c|M.abscessus_ATCC_199 GTITAGRTALNTSAITGESVPVEAGPG----------------DEVFAGS
. : * : :: . ::** :*. . * ..:
MAV_5246|M.avium_104 VNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVP
TH_2531|M.thermoresistible__bu VATDSGLRITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADTAAGWLFW
MLBr_00747|M.leprae_Br4923 VVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVP
Rv3743c|M.tuberculosis_H37Rv VNGTGALRIRVDRLARDSVVARIATLVEQASQTKARTQLFIEKVEQRYSI
Mb3769c|M.bovis_AF2122/97 VNGTGALRIRVDRLARDSVVARIATLVEQASQTKARTQLFIEKVEQRYSI
MMAR_2275|M.marinum_M VNGSGVLQLLVTRDPSQTVVARIVELVSEASATKAKTQLFIEKIEQRYSI
MUL_1477|M.ulcerans_Agy99 VNGSGVLQLLVTRDPSQTVVARIVERVSEASATKAKTQLFIEKIEQRYSI
MSMEG_5403|M.smegmatis_MC2_155 VNGSGALRVEVTREPSQTVVARIVAMVTEASATKATTQLFIEKIEQRYSA
Mvan_3729|M.vanbaalenii_PYR-1 VNGTGTLRVRVTRPAADTVIARIIAMVSEASASKAKMQLFIEKIEQRYSI
Mflv_2822|M.gilvum_PYR-GCK INGAGAIEIQVTRLASDSTLARVVRLVAEAQTKTTSTQRFTDRFQRIFVP
MAB_4853c|M.abscessus_ATCC_199 INGNGVLQVRVSATAADNSLARIVAIVEAEQSRKGASQRLADRIAKPLVP
: . : : . .. :. : * . * . :
MAV_5246|M.avium_104 VVLLLAVATLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVG
TH_2531|M.thermoresistible__bu FALGAALLTALVWAVLH-RPDFAVVRTITVLVIACPHALGLAIPLVVAIA
MLBr_00747|M.leprae_Br4923 TSFVVSAITLAITKDVR--------RTMTVLLIACPCAVGLATPTAISAA
Rv3743c|M.tuberculosis_H37Rv GMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAA
Mb3769c|M.bovis_AF2122/97 GMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAA
MMAR_2275|M.marinum_M GVVIATLALIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSA
MUL_1477|M.ulcerans_Agy99 GVVIATLALIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSA
MSMEG_5403|M.smegmatis_MC2_155 GVVVATLALLTVPLMFGADLRSTLLRAMTFMIVASPCAVVLATMPPLLSA
Mvan_3729|M.vanbaalenii_PYR-1 GMVLATIALFTIPLVLGADLQPTLLRAMTFMIVASPCALVLSTMPPLLSA
Mflv_2822|M.gilvum_PYR-GCK VVLVGVVLLLFAGFVVDEPFTDTVYRALAVLVAASPCALAIATPSAVLSA
MAB_4853c|M.abscessus_ATCC_199 AIMITAAAIAVLGSVFGDPLV-WIERALVVLVAASPCALAISVPVTVVAA
. ::..:: *.* *: :: : .
MAV_5246|M.avium_104 TGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAAD-G
TH_2531|M.thermoresistible__bu TERAARGGVLIKDRIALENMRTVDVVLFDKTGTLTKGQPAVTGITAAG-A
MLBr_00747|M.leprae_Br4923 IGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMH-K
Rv3743c|M.tuberculosis_H37Rv IANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYE-R
Mb3769c|M.bovis_AF2122/97 IANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYE-R
MMAR_2275|M.marinum_M IANAGRHGVLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLS-V
MUL_1477|M.ulcerans_Agy99 IADAGRHGVLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLS-A
MSMEG_5403|M.smegmatis_MC2_155 IANASRHGVLVKSAVAMERLADTDVVVLDKTGTLTAGEPVISRVTVLI-D
Mvan_3729|M.vanbaalenii_PYR-1 IANAGRHGVLVKSAVVLEKLSTVTHVAFDKTGTLTEGSPRLVHIRPVPDA
Mflv_2822|M.gilvum_PYR-GCK VARAARAGILMKGGAALEELGRVNVLAFDKTGTLTEGRPRIADVCATA--
MAB_4853c|M.abscessus_ATCC_199 IGAASKLGVLVKGGAALEALGVVRTIALDKTGTLTANRPTVIEVAATA--
..: *:* *. :* . : :*****:* . : :
MAV_5246|M.avium_104 TDR-ATLLRYAGALEAASEHPIAHAIARDA--KAELGPLPTPTGFRAVGG
TH_2531|M.thermoresistible__bu HSE-EDVLRLAAAAEAPSEHPLARALVAAA--QRHGTDLPPATDFASTPG
MLBr_00747|M.leprae_Br4923 DWSPEQVLAYAASSEIHSRHPLAEAVIRST--EERHISIPPHEECEVLVG
Rv3743c|M.tuberculosis_H37Rv RFTDDELLRLAAAAEYPSEHPLGAAIVKAA--QSRRIRLPTVGEFTAHPG
Mb3769c|M.bovis_AF2122/97 RFTDDELLRLAAAAEYPSEHPLGAAIVKAA--QSRRIRLPTVGEFTAHPG
MMAR_2275|M.marinum_M DVGIKKLLQLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPG
MUL_1477|M.ulcerans_Agy99 DVGIKKLLQLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPG
MSMEG_5403|M.smegmatis_MC2_155 GA---DVLGMAAAAEQFSEHPLGRAIVAAA--RGR--VVPEAGDFTALPG
Mvan_3729|M.vanbaalenii_PYR-1 AVDDAELLALAAAAENPSEHPLARAIVAAA--RDAGLTLQPVEDFGSTPG
Mflv_2822|M.gilvum_PYR-GCK DSDDAELLRIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRATDVRAVIG
MAB_4853c|M.abscessus_ATCC_199 GATGERVLSAAAALESRSEHPLAAAILAA-----AGSVDP-ADDVEAVTS
:* * : * * **:. *: .
MAV_5246|M.avium_104 GGVHGRVDGHAVAIGRPSWLAERG--LRPDAALAAAAARAEHDGKTVVAV
TH_2531|M.thermoresistible__bu LGVRARVAGRTVRVGGPRLLAETG--QTAPAGSEGWRAR----GSTVLYV
MLBr_00747|M.leprae_Br4923 LGMRTWADGRTLLLGSPSLLCAEK--VKVSKTASEWVDKLRHQTETPLLF
Rv3743c|M.tuberculosis_H37Rv CRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVV
Mb3769c|M.bovis_AF2122/97 CRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVV
MMAR_2275|M.marinum_M RGVRASVGREFVEVCSPHSYRG---------APLPELAPILEAGATAAIV
MUL_1477|M.ulcerans_Agy99 RGVRASVGREFVEVCSPHSYRG---------APLPELAPILEAGATAAIV
MSMEG_5403|M.smegmatis_MC2_155 RGVRARVAGHVVEVVSPAAYAGEN------AAVREHCAAIENDGGTAVVV
Mvan_3729|M.vanbaalenii_PYR-1 HGVRARIGEDLVEVGNPTLLPAVR------EIAHEMVDDLEQTGHTAVIV
Mflv_2822|M.gilvum_PYR-GCK RGIVASVEGVEVCIGKTELFTDAAQPP--PAELAAEVNRLEQAGRTTMLV
MAB_4853c|M.abscessus_ATCC_199 AGLTGRRGGHTLRLGRPGWID--------PGSLAPDVARMQQGGATAVLV
: : : . * .
MAV_5246|M.avium_104 GWDGRARGILALADTVKPSSAAAVRQFTRLGLT-PILLTGDNHTVARRTA
TH_2531|M.thermoresistible__bu LVDDMIAGAVALADEIRPESRPTVDALHRQGID-VALITGDARSVAESVA
MLBr_00747|M.leprae_Br4923 AVDGTLVGLISLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVA
Rv3743c|M.tuberculosis_H37Rv VCDSHPVGLLAITDQLRPEAAAAISAATKLTGAKPVLLTGDNRATADRLG
Mb3769c|M.bovis_AF2122/97 VCDSHPVGLLAITDQLRPEAAAAISAATKLTGAKPVLLTGDNRATADRLG
MMAR_2275|M.marinum_M LRNGVAIGVLGLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVA
MUL_1477|M.ulcerans_Agy99 LRNGVAIGVLGLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVA
MSMEG_5403|M.smegmatis_MC2_155 LEDGLPVGVIGLADRLRPDAPAAVMQLAQLTKHPPMLLTGDNRRAAGRLA
Mvan_3729|M.vanbaalenii_PYR-1 RLNGTVVGVLGLTDRVRDAAADMVAALTELTGAQPILLTGDNPRAAAALA
Mflv_2822|M.gilvum_PYR-GCK RAGDRWLGAIGLMDLPRPEASAVIARLAALGVKNTVMLSGDNQRVADAVA
MAB_4853c|M.abscessus_ATCC_199 EEDGQLLGAIAVRDELRPEAAHVIAALHRSGYR-VAMLTGDNAATATTLA
.. * :.: * : : : :::** * .
MAV_5246|M.avium_104 GELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLG
TH_2531|M.thermoresistible__bu AELGIDRVLADVPPEHKAAKVVELQREGRRVAMVGDGVNDAPALARADVG
MLBr_00747|M.leprae_Br4923 TELGIDEWRAEVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIG
Rv3743c|M.tuberculosis_H37Rv VQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVG
Mb3769c|M.bovis_AF2122/97 VQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVG
MMAR_2275|M.marinum_M QHAGITDVRAALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTS
MUL_1477|M.ulcerans_Agy99 QHAGITDVRAALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTS
MSMEG_5403|M.smegmatis_MC2_155 EEAGIADVHAELLPDGKAAAVQKLQRDNTHVLVVGDGVNDAPAMAAAHTS
Mvan_3729|M.vanbaalenii_PYR-1 AQVGITDVRAGLLPQDKVEAVRELEAAGAKVMLVGDGVNDAPAMALATVG
Mflv_2822|M.gilvum_PYR-GCK AEVGVAHARGDLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGASVG
MAB_4853c|M.abscessus_ATCC_199 RQVGIDTVHADLRPEDKARIITELRQQHP-TAMVGDGVNDAPALATADLG
. *: . * * : *. :****:***.*:* * .
MAV_5246|M.avium_104 LAMG-TGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFG
TH_2531|M.thermoresistible__bu IAIG-AGTDVAIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWWAAG
MLBr_00747|M.leprae_Br4923 IAMGLAGTDVAVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIA
Rv3743c|M.tuberculosis_H37Rv IAMGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVT
Mb3769c|M.bovis_AF2122/97 IAMGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVT
MMAR_2275|M.marinum_M VAMG-AGADLTLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGT
MUL_1477|M.ulcerans_Agy99 VAMG-AGADPTLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGT
MSMEG_5403|M.smegmatis_MC2_155 IAMGRAGADLTVQTADVVTIRDELATVPAVIALARRARRVVIANLVMAGA
Mvan_3729|M.vanbaalenii_PYR-1 VAKGRTGSDLALATADAVITRDDLSTIPAVLALARRARRLVIANLTIAAT
Mflv_2822|M.gilvum_PYR-GCK IAMGAAGSDVALETADVALMADDLRALPFAISLSRRSSRVIKQNLWASLG
MAB_4853c|M.abscessus_ATCC_199 IAMGAMGTDVAIETADVALMGEDLRHLTQALAHARRARTIMLQNVGLSLA
:* * :: :: :*. . : . : : * :
MAV_5246|M.avium_104 YNLAAIPLAA-----LGMLNPMLAGAA-MALSSVLVVGNS-----LRLRS
TH_2531|M.thermoresistible__bu YNLIAVPLAAGVLAPAGFVMPMSVGAILMSLSTVVVALNAQLLRRLDLRP
MLBr_00747|M.leprae_Br4923 VNAAGLFIGAG-----GALSPVLAAVLHNASSVAVVANSS---RLIRYRL
Rv3743c|M.tuberculosis_H37Rv FIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLNGLRL-----LRHTAWRR
Mb3769c|M.bovis_AF2122/97 FIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLNGLRL-----LRHTAWRR
MMAR_2275|M.marinum_M FISVLVLWDLFGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRA
MUL_1477|M.ulcerans_Agy99 FISVLVLWDLFGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRA
MSMEG_5403|M.smegmatis_MC2_155 AITTLVLWDLFGQLPLPLGVAGHEGSTILVALNGLRL-----LSNRAWIS
Mvan_3729|M.vanbaalenii_PYR-1 LITVLVAWDLIGHLPLPLGVAGHEGSTIVVGLNGLRL-----LRDAAWPS
Mflv_2822|M.gilvum_PYR-GCK IVAVLIPATIFG-LGIGPAVLIHEGSTLIVVANALRL-----LGMPMQSV
MAB_4853c|M.abscessus_ATCC_199 LIAVLIPLALLGILGLAAVVAVHELAEIVVIANGVRAGRTQPLTAPEHAN
: :
MAV_5246|M.avium_104 FASIIPGA------
TH_2531|M.thermoresistible__bu EQSLAAARR-----
MLBr_00747|M.leprae_Br4923 D-------------
Rv3743c|M.tuberculosis_H37Rv AAGTAHR-------
Mb3769c|M.bovis_AF2122/97 AAGTAHR-------
MMAR_2275|M.marinum_M AASPVR--------
MUL_1477|M.ulcerans_Agy99 AASPVR--------
MSMEG_5403|M.smegmatis_MC2_155 PGATPT--------
Mvan_3729|M.vanbaalenii_PYR-1 TRGTKATAKTGK--
Mflv_2822|M.gilvum_PYR-GCK TPAAPRVERAEETP
MAB_4853c|M.abscessus_ATCC_199 TPAAQLAQQE----