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MTLTAFEVSAAEASSDRPDRIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTGLVAQLNGAAEPVWWTL YLACYLAGGWGSAWAGAQALRNRALDVDLLMIVAAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTAD SVKGLLDLAPEQATVFDVDGNEQVVAASELVVGDRVVVRPGERIPADGAVLSGCSEVDQCSITGESMPAA KGRGDEVFAGTVNGSGVLQLLVTRDPSQTVVARIVELVSEASATKAKTQLFIEKIEQRYSIGVVIATLAL IAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAIVVEHLADTGVVALD KTGTLTFGLPQLAIVEPLSVDVGIKKLLQLAAAAEQSSEHPLGRAIVEEVRRRGITIPGAEDFRALPGRG VRASVGREFVEVCSPHSYRGAPLPELAPILEAGATAAIVLRNGVAIGVLGLTDQVRADAAPSVAALTALT SAPPVLLTGDNPCAAQRVAQHAGITDVRAALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTSV AMGAGADLTLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGTFISVLVLWDLFGQLPLPLGVAG HEGSTVLVALNGMRLLTNRSWRAAASPVR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2275 | ctpD | - | 100% (659) | cation transporter p-type ATPase D CtpD |
M. marinum M | MMAR_2140 | - | 1e-93 | 36.38% (613) | metal cation transporter p-type ATPase |
M. marinum M | MMAR_4876 | ctpV | 5e-77 | 32.99% (673) | metal cation transporter p-type ATPase, CtpV |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1504 | ctpD | 0.0 | 81.52% (660) | cation transporter P-type ATPase D |
M. gilvum PYR-GCK | Mflv_2822 | - | 1e-103 | 37.38% (634) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv1469 | ctpD | 0.0 | 81.52% (660) | cation transporter P-type ATPase D |
M. leprae Br4923 | MLBr_01987 | ctpA | 1e-65 | 33.21% (557) | putative cation-transporting ATPase |
M. abscessus ATCC 19977 | MAB_4853c | - | 7e-97 | 35.62% (612) | cation-transporting ATPase G |
M. avium 104 | MAV_5246 | - | 8e-73 | 36.11% (540) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5403 | cadA | 0.0 | 67.30% (636) | cadmium-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_2531 | - | 4e-73 | 33.79% (651) | PUTATIVE copper-translocating P-type ATPase |
M. ulcerans Agy99 | MUL_1477 | ctpD | 0.0 | 99.09% (659) | cation transporter p-type ATPase D CtpD |
M. vanbaalenii PYR-1 | Mvan_3729 | - | 0.0 | 61.15% (641) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALD MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01987|M.leprae_Br4923 -------------------------------------------------- MAV_5246|M.avium_104 -------------------------------------------------- TH_2531|M.thermoresistible__bu -------------------------------------------------- MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK LTDLLPDSDERCADRLTRGLVDDGIIEQAHVIDGDTPKPRLCVHYDAEAA MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01987|M.leprae_Br4923 ---------------------------------MRAPN---GWNNLPNKL MAV_5246|M.avium_104 ---------------------------------MSTPPRHIDEGTFPDHT TH_2531|M.thermoresistible__bu -------------------------------------------------- MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK SATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTALVDTLSTIPGV MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01987|M.leprae_Br4923 SDFS------TLVNSATRVAAIN--LSEVT-QTAEVCEAVRRAALCTDGG MAV_5246|M.avium_104 ASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYATEKAAVSAPAS TH_2531|M.thermoresistible__bu ------------------------MVGPAHHGTVAADGRAQHLTGRDHHR MMAR_2275|M.marinum_M -------------------------------MTLTAFEVSAAEASSDRPD MUL_1477|M.ulcerans_Agy99 -------------------------------MTLTAFEVSAAEASSDRSD Mb1504|M.bovis_AF2122/97 -------------------------------MTLTACEVTAAEAPFDR-- Rv1469|M.tuberculosis_H37Rv -------------------------------MTLTACEVTAAEAPFDR-- MSMEG_5403|M.smegmatis_MC2_155 ---------------------------------MTALYPAVEPAPAAR-- Mvan_3729|M.vanbaalenii_PYR-1 --------------------------MRVCAGIVVRVSADLQAADWERTT Mflv_2822|M.gilvum_PYR-GCK VAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHD-- MAB_4853c|M.abscessus_ATCC_199 -------------------------------MSDACGCGHDEPATGDE-- MLBr_01987|M.leprae_Br4923 EALQRRQADADNARY--------------LLIRLAVAAALFVPLAHLSVM MAV_5246|M.avium_104 YDPQTLITEIENAGYAAAVATPSPPRDDPELASLRRRLVTAIALAGPVIA TH_2531|M.thermoresistible__bu HGHGDHAGHVAEFRR--------------LFWVMLLLAVPTVAFSGMFAM MMAR_2275|M.marinum_M RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW MUL_1477|M.ulcerans_Agy99 RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW Mb1504|M.bovis_AF2122/97 -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW Rv1469|M.tuberculosis_H37Rv -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW MSMEG_5403|M.smegmatis_MC2_155 -----PARPRS-GGWLWTVPSVRWAAAALALFLTG-LAAQLLGAPQAVVW Mvan_3729|M.vanbaalenii_PYR-1 ATGEEVRGWRAPRSSAWSLPEVRWALIATVLFVVG-GLAQLVGAPPWLYW Mflv_2822|M.gilvum_PYR-GCK --GDGADHQHGHGGISGERTELVFAGLAGALLLTGWLLAAFADTPRSAEV MAB_4853c|M.abscessus_ATCC_199 --VDGEREPERLWEVS----ELRFAAVAGVVLLAGYVVG-WTGGSHPVEI MLBr_01987|M.leprae_Br4923 FAVLPSTHFPGWEWMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLI MAV_5246|M.avium_104 VAMIPALQFQHWHWAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLI TH_2531|M.thermoresistible__bu ILGYQVPRVPGAQWVSPVLGTVMYVWGGRPFLTGAISEIRSRTPGMMLLI . . . MMAR_2275|M.marinum_M TLYLACYLAGGWGSAWAGAQALRNRALDVDLLMIVAAIGAVAIG----QI MUL_1477|M.ulcerans_Agy99 TLYLACYLAGGWGSAWAGAQALRNRALDVDLLMIVAAIGAVAIG----QI Mb1504|M.bovis_AF2122/97 TLYLACYLAGGWGSAWAGAQALRNKALDVDLLMIAAAVGAVAIG----QI Rv1469|M.tuberculosis_H37Rv TLYLACYLAGGWGSAWAGAQALRNKALDVDLLMIAAAVGAVAIG----QI MSMEG_5403|M.smegmatis_MC2_155 TLYLACYVVGGWEPAWVGVRALRNRTLDVDLLMIVAAIGAATIG----QV Mvan_3729|M.vanbaalenii_PYR-1 TLYLACYVTGGWEPGWAGLQALRDKTLDVDLLMVAAAIGAAAIG----QV Mflv_2822|M.gilvum_PYR-GCK VVYGLAFFFGAFFTVQEAFASVRQGRFEIDFLMLVSAAGAAALG----EV MAB_4853c|M.abscessus_ATCC_199 GLYAAALAIGAYTFVPSTLRRLARGKIGVGTLMTIAAIGAVILG----EV MLBr_01987|M.leprae_Br4923 STGITAATIWSLYT-VFGHHQSTEHRGVWRALLGSDA----------IYF MAV_5246|M.avium_104 SIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYF TH_2531|M.thermoresistible__bu GLALTVAFLSSWGASLGVLDHRLEFWWELALLI----------------- . : MMAR_2275|M.marinum_M FDGALLIVIFATSGALDDVATKHTADSVKGLLDLAPEQA-TVFDV--DGN MUL_1477|M.ulcerans_Agy99 FDGALLIVIFATSGALDDVATKHTADSVKGLLDLAPEQA-TVFDV--DGN Mb1504|M.bovis_AF2122/97 FDGALLIVIFATSGALDDIATRHTAESVKGLLDLAPDQA-VVVQG--DGS Rv1469|M.tuberculosis_H37Rv FDGALLIVIFATSGALDDIATRHTAESVKGLLDLAPDQA-VVVQG--DGS MSMEG_5403|M.smegmatis_MC2_155 FDGALLIVIFATSGALEDVATTRTERSVRGLLDLAPEHA-TLLG---DGS Mvan_3729|M.vanbaalenii_PYR-1 FDGALLIVIFATSGALEAVATKRTEDSVRGLLDLAPDTA-TRLTD--SGA Mflv_2822|M.gilvum_PYR-GCK AEGALLLFLFSVGHALEGYAMGRARRAIEALAELAPKTALVRRGG--TGD MAB_4853c|M.abscessus_ATCC_199 GEAAMLAFLFSISEGLEEYALARTRRGLRALLSLAPEEATVLRDG--T-- MLBr_01987|M.leprae_Br4923 EVAAGITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVLQP---DGS MAV_5246|M.avium_104 EVAAGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR----AGA TH_2531|M.thermoresistible__bu -------VIMLLGHWIELRSLARTTSALDSLAALLPDTAERVEQGPDGET .:. . : : .: .* * .. . MMAR_2275|M.marinum_M EQVVAASELVVGDRVVVRPGERIPADGAVLSGCSEVDQCSITGESMPAAK MUL_1477|M.ulcerans_Agy99 EQVVAASELVVGDRVVVRPGERIPADGAVLSGCSEVDQCSIAGESMPAAK Mb1504|M.bovis_AF2122/97 ERVVAASELVVGDRVVVRPGDRIPADGAVLSGASDVDQRSITGESMPVAK Rv1469|M.tuberculosis_H37Rv ERVVAASELVVGDRVVVRPGDRIPADGAVLSGASDVDQRSITGESMPVAK MSMEG_5403|M.smegmatis_MC2_155 QRVVAAADLRPGDVIVVRPGERISADGTVIGGASEVDQSSITGEPLPAAK Mvan_3729|M.vanbaalenii_PYR-1 EEVVDTAVLDVGDVLMIRPGERIGGDGTVVDGASEVDQATITGEPLPVDK Mflv_2822|M.gilvum_PYR-GCK TVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQAPVTGESVPVDK MAB_4853c|M.abscessus_ATCC_199 ETTITATELQVGDTMLVRPGERVATDGTITAGRTALNTSAITGESVPVEA MLBr_01987|M.leprae_Br4923 EMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAKPVRV MAV_5246|M.avium_104 ETRIPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEV TH_2531|M.thermoresistible__bu VTVVAPADLRVGDTVIVRPGAGIPADGRIIDGVADVDESMVTGESVPVRR : * : .::**. : ** : * : :. ::**. *. MMAR_2275|M.marinum_M GRG----------------DEVFAGTVNGSGVLQLLVTRDPSQTVVARIV MUL_1477|M.ulcerans_Agy99 GRG----------------DEVFAGTVNGSGVLQLLVTRDPSQTVVARIV Mb1504|M.bovis_AF2122/97 ARG----------------DEVFAGTVNGSGVLHLVVTRDPSQTVVARIV Rv1469|M.tuberculosis_H37Rv ARG----------------DEVFAGTVNGSGVLHLVVTRDPSQTVVARIV MSMEG_5403|M.smegmatis_MC2_155 DVG----------------DDVFAGTVNGSGALRVEVTREPSQTVVARIV Mvan_3729|M.vanbaalenii_PYR-1 ATG----------------DEVFAGTVNGTGTLRVRVTRPAADTVIARII Mflv_2822|M.gilvum_PYR-GCK IPVPDVAAAAASPELIDAASRVFAGTINGAGAIEIQVTRLASDSTLARVV MAB_4853c|M.abscessus_ATCC_199 GPG----------------DEVFAGSINGNGVLQVRVSATAADNSLARIV MLBr_01987|M.leprae_Br4923 NPG----------------AQVIGGTVVLNGRLIVEAAAVGDETQLAGMV MAV_5246|M.avium_104 GVG----------------DGVTGGTVNAGGRLVVRATGIGDDTQLARMA TH_2531|M.thermoresistible__bu GVG----------------DRVVAATVATDSGLRITVTAVGDDTALAGIR * ..:: . : : .: :. :* : MMAR_2275|M.marinum_M ELVSEASATKAKTQLFIEKIEQRYSIGVVIATLALIAIPLMLGTPVQVVL MUL_1477|M.ulcerans_Agy99 ERVSEASATKAKTQLFIEKIEQRYSIGVVIATLALIAIPLMLGTPVQVVL Mb1504|M.bovis_AF2122/97 ELVADASATKAKTQLFIEKIEQRYSLGMVAATLALIVIPLMFGADLRPVL Rv1469|M.tuberculosis_H37Rv ELVADASATKAKTQLFIEKIEQRYSLGMVAATLALIVIPLMFGADLRPVL MSMEG_5403|M.smegmatis_MC2_155 AMVTEASATKATTQLFIEKIEQRYSAGVVVATLALLTVPLMFGADLRSTL Mvan_3729|M.vanbaalenii_PYR-1 AMVSEASASKAKMQLFIEKIEQRYSIGMVLATIALFTIPLVLGADLQPTL Mflv_2822|M.gilvum_PYR-GCK RLVAEAQTKTTSTQRFTDRFQRIFVPVVLVGVVLLLFAGFVVDEPFTDTV MAB_4853c|M.abscessus_ATCC_199 AIVEAEQSRKGASQRLADRIAKPLVPAIMITAAAIAVLGSVFGDPLV-WI MLBr_01987|M.leprae_Br4923 RLVEQAQQQNANAQRLADRIASVFVPCVFAVAALTAVGWLIAGSGPDRVF MAV_5246|M.avium_104 QLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATLAGWLAAGGTLATAL TH_2531|M.thermoresistible__bu RMVAEAQSSSSRAQRIADTAAGWLFWFALGAALLTALVWAVLHR-PDFAV * . . * : : . . . MMAR_2275|M.marinum_M LRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAIVVEHLADTG MUL_1477|M.ulcerans_Agy99 LRAMTFMIVASPCAVVLATMPPLLSAIADAGRHGVLVKSAIVVEHLADTG Mb1504|M.bovis_AF2122/97 LRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAVVVERLADTS Rv1469|M.tuberculosis_H37Rv LRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAVVVERLADTS MSMEG_5403|M.smegmatis_MC2_155 LRAMTFMIVASPCAVVLATMPPLLSAIANASRHGVLVKSAVAMERLADTD Mvan_3729|M.vanbaalenii_PYR-1 LRAMTFMIVASPCALVLSTMPPLLSAIANAGRHGVLVKSAVVLEKLSTVT Mflv_2822|M.gilvum_PYR-GCK YRALAVLVAASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVN MAB_4853c|M.abscessus_ATCC_199 ERALVVLVAASPCALAISVPVTVVAAIGAASKLGVLVKGGAALEALGVVR MLBr_01987|M.leprae_Br4923 SAAIAVLVIACPCALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVD MAV_5246|M.avium_104 TAAVAVLIIACPCALGLATPTALLVGTGRAAQLGVLIKGPEVLETTRAVD TH_2531|M.thermoresistible__bu VRTITVLVIACPHALGLAIPLVVAIATERAARGGVLIKDRIALENMRTVD ::..:: *.* *: :: : . ..: *:*:*. .* . MMAR_2275|M.marinum_M VVALDKTGTLTFGLPQLAIVEPLSVDVG-IKKLLQLAAAAEQSSEHPLGR MUL_1477|M.ulcerans_Agy99 VVALDKTGTLTFGLPQLAIVEPLSADVG-IKKLLQLAAAAEQSSEHPLGR Mb1504|M.bovis_AF2122/97 IVALDKTGTLTRGIPRLASVAPLDPNVVDARRLLQLAAAAEQSSEHPLGR Rv1469|M.tuberculosis_H37Rv IVALDKTGTLTRGIPRLASVAPLDPNVVDARRLLQLAAAAEQSSEHPLGR MSMEG_5403|M.smegmatis_MC2_155 VVVLDKTGTLTAGEPVISRVTVLIDGAD----VLGMAAAAEQFSEHPLGR Mvan_3729|M.vanbaalenii_PYR-1 HVAFDKTGTLTEGSPRLVHIRPVPDAAVDDAELLALAAAAENPSEHPLAR Mflv_2822|M.gilvum_PYR-GCK VLAFDKTGTLTEGRPRIADVCATADSDD--AELLRIAVAVEEQSDHPLAR MAB_4853c|M.abscessus_ATCC_199 TIALDKTGTLTANRPTVIEVAATAGATG--ERVLSAAAALESRSEHPLAA MLBr_01987|M.leprae_Br4923 TVVFDKTGTLTTGQLKVSAVTAAPGWQA--NEVLQMAATVESASEHAVAL MAV_5246|M.avium_104 TVVLDKTGTVTTGAMTVLDVVAADGTDR--ATLLRYAGALEAASEHPIAH TH_2531|M.thermoresistible__bu VVLFDKTGTLTKGQPAVTGITAAGAHSE--EDVLRLAAAAEAPSEHPLAR : :*****:* . : : :* * : * *:*.:. MMAR_2275|M.marinum_M AIVEEV--RRRGITIPGAEDFRALPGRGVRASVGREFVEVCSPHSYRG-- MUL_1477|M.ulcerans_Agy99 AIVEEV--RRRGITIPGAEDFRALPGRGVRASVGREFVEVCSPHSYRG-- Mb1504|M.bovis_AF2122/97 AIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVGNDFVEIASPQSYRG-- Rv1469|M.tuberculosis_H37Rv AIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVGNDFVEIASPQSYRG-- MSMEG_5403|M.smegmatis_MC2_155 AIVAAA--RGR--VVPEAGDFTALPGRGVRARVAGHVVEVVSPAAYAGE- Mvan_3729|M.vanbaalenii_PYR-1 AIVAAA--RDAGLTLQPVEDFGSTPGHGVRARIGEDLVEVGNPTLLPAV- Mflv_2822|M.gilvum_PYR-GCK AIVRDGRERLAGAVTPRATDVRAVIGRGIVASVEGVEVCIGKTELFTDAA MAB_4853c|M.abscessus_ATCC_199 AILAA-----AGSVDP-ADDVEAVTSAGLTGRRGGHTLRLGRPGWID--- MLBr_01987|M.leprae_Br4923 AIA-ASTTHREP--VAN---FRAVPGHGVSGTVAERAVRVGKPSWIASR- MAV_5246|M.avium_104 AIARDAKAELGP--LPTPTGFRAVGGGGVHGRVDGHAVAIGRPSWLAERG TH_2531|M.thermoresistible__bu ALVAAAQRHGTD--LPPATDFASTPGLGVRARVAGRTVRVGGPRLLAETG *: . : . *: . : : . MMAR_2275|M.marinum_M -----APLPELAPILEAGATAAIVLRNGVAIGVLGLTDQVRADAAPSVAA MUL_1477|M.ulcerans_Agy99 -----APLPELAPILEAGATAAIVLRNGVAIGVLGLTDQVRADAAPSVAA Mb1504|M.bovis_AF2122/97 -----APLAELAPLLSAGATAAIVLLDGVAIGVLGLTDQLRPDAVESVAA Rv1469|M.tuberculosis_H37Rv -----APLAELAPLLSAGATAAIVLLDGVAIGVLGLTDQLRPDAVESVAA MSMEG_5403|M.smegmatis_MC2_155 ---NAAVREHCAAIENDGGTAVVVLEDGLPVGVIGLADRLRPDAPAAVMQ Mvan_3729|M.vanbaalenii_PYR-1 ---REIAHEMVDDLEQTGHTAVIVRLNGTVVGVLGLTDRVRDAAADMVAA Mflv_2822|M.gilvum_PYR-GCK QPPPAELAAEVNRLEQAGRTTMLVRAGDRWLGAIGLMDLPRPEASAVIAR MAB_4853c|M.abscessus_ATCC_199 ---PGSLAPDVARMQQGGATAVLVEEDGQLLGAIAVRDELRPEAAHVIAA MLBr_01987|M.leprae_Br4923 -CNSTTLVTARRNAELRGETAVFVEIDGEQCGVIAVADAVKASAADAVAA MAV_5246|M.avium_104 LRPDAALAAAAARAEHDGKTVVAVGWDGRARGILALADTVKPSSAAAVRQ TH_2531|M.thermoresistible__bu ----QTAPAGSEGWRARGSTVLYVLVDDMIAGAVALADEIRPESRPTVDA * *. * .. * :.: * : : : MMAR_2275|M.marinum_M LTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRAALLPEQKVEAVQALQA MUL_1477|M.ulcerans_Agy99 LTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRAALLPEQKVEAVQALQA Mb1504|M.bovis_AF2122/97 MAALTAAPPVLLTGDNGRAAWRVARNAGITDVRAALLPEQKVEVVRNLQA Rv1469|M.tuberculosis_H37Rv MAALTAAPPVLLTGDNGRAAWRVARNAGITDVRAALLPEQKVEVVRNLQA MSMEG_5403|M.smegmatis_MC2_155 LAQLTKHPPMLLTGDNRRAAGRLAEEAGIADVHAELLPDGKAAAVQKLQR Mvan_3729|M.vanbaalenii_PYR-1 LTELTGAQPILLTGDNPRAAAALAAQVGITDVRAGLLPQDKVEAVRELEA Mflv_2822|M.gilvum_PYR-GCK LAALGVKNTVMLSGDNQRVADAVAAEVGVAHARGDLMPEDKVAQIAALRE MAB_4853c|M.abscessus_ATCC_199 LHRSGYR-VAMLTGDNAATATTLARQVGIDTVHADLRPEDKARIITELRQ MLBr_01987|M.leprae_Br4923 LHDRGFR-TALLTGDNPASAAAVASRIGIDEVIADILPEDKVDVIEQLRD MAV_5246|M.avium_104 FTRLGLT-PILLTGDNHTVARRTAGELGIGEVISGALPADKVEAVKRLQS TH_2531|M.thermoresistible__bu LHRQGID-VALITGDARSVAESVAAELGIDRVLADVPPEHKAAKVVELQR : :::** * * . *: . . * *. : *. MMAR_2275|M.marinum_M SGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADLTLQTADGVTVRDELHT MUL_1477|M.ulcerans_Agy99 SGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADPTLQTADGVTVRDELHT Mb1504|M.bovis_AF2122/97 GGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADLTLQTADGVTIRDELHT Rv1469|M.tuberculosis_H37Rv GGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADLTLQTADGVTIRDELHT MSMEG_5403|M.smegmatis_MC2_155 DNTHVLVVGDGVNDAPAMAAAHTSIAMGRAGADLTVQTADVVTIRDELAT Mvan_3729|M.vanbaalenii_PYR-1 AGAKVMLVGDGVNDAPAMALATVGVAKGRTGSDLALATADAVITRDDLST Mflv_2822|M.gilvum_PYR-GCK RHGRVGMVGDGVNDAPAMAGASVGIAMGAAGSDVALETADVALMADDLRA MAB_4853c|M.abscessus_ATCC_199 QHP-TAMVGDGVNDAPALATADLGIAMGAMGTDVAIETADVALMGEDLRH MLBr_01987|M.leprae_Br4923 RGHVVAMVGDGINDGPALARADLGMAIG-RGTDVAIGAADIILVRDNLDV MAV_5246|M.avium_104 AGRVVAMVGDGVNDAAALAAADLGLAMG-TGTDVAIEAADVTVVRGDLRA TH_2531|M.thermoresistible__bu EGRRVAMVGDGVNDAPALARADVGIAIG-AGTDVAIASAGVVLAGSDPRS . :****:**..*:* * .:* * *:* :: :*. : MMAR_2275|M.marinum_M IPTLIGLARQARRVVTANLFIAGTFISVLVLWDLFGQLPLPLGVAGHEGS MUL_1477|M.ulcerans_Agy99 IPTLIGLARQARRVVTANLFIAGTFISVLVLWDLFGQLPLPLGVAGHEGS Mb1504|M.bovis_AF2122/97 IPTIIGLARQARRVVTVNLAIAATFIAVLVLWDLFGQLPLPLGVVGHEGS Rv1469|M.tuberculosis_H37Rv IPTIIGLARQARRVVTVNLAIAATFIAVLVLWDLFGQLPLPLGVVGHEGS MSMEG_5403|M.smegmatis_MC2_155 VPAVIALARRARRVVIANLVMAGAAITTLVLWDLFGQLPLPLGVAGHEGS Mvan_3729|M.vanbaalenii_PYR-1 IPAVLALARRARRLVIANLTIAATLITVLVAWDLIGHLPLPLGVAGHEGS Mflv_2822|M.gilvum_PYR-GCK LPFAISLSRRSSRVIKQNLWASLGIVAVLIPATIFG-LGIGPAVLIHEGS MAB_4853c|M.abscessus_ATCC_199 LTQALAHARRARTIMLQNVGLSLALIAVLIPLALLGILGLAAVVAVHELA MLBr_01987|M.leprae_Br4923 VPITLDLAAATMRTIKFNMVWAFGYNIAAIPIAA-----AGLLNPLVAGA MAV_5246|M.avium_104 AVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAA-----LGMLNPMLAGA TH_2531|M.thermoresistible__bu VLSVLQLSRAAYRKMKQNLWWAAGYNLIAVPLAAGVLAPAGFVMPMSVGA : : : : *: : : : MMAR_2275|M.marinum_M TVLVALNGMRL-----LTNRSWRAAASPVR-------------------- MUL_1477|M.ulcerans_Agy99 TVLVALNGMRL-----LTNRSWRAAASPVR-------------------- Mb1504|M.bovis_AF2122/97 TVLVALNGMRL-----LTNRSWRAAASAAR-------------------- Rv1469|M.tuberculosis_H37Rv TVLVALNGMRL-----LTNRSWRAAASAAR-------------------- MSMEG_5403|M.smegmatis_MC2_155 TILVALNGLRL-----LSNRAWISPGATPT-------------------- Mvan_3729|M.vanbaalenii_PYR-1 TIVVGLNGLRL-----LRDAAWPSTRGTKATAKTGK-------------- Mflv_2822|M.gilvum_PYR-GCK TLIVVANALRL-----LGMPMQSVTPAAPRVERAEETP------------ MAB_4853c|M.abscessus_ATCC_199 EIVVIANGVRAGRTQPLTAPEHANTPAAQLAQQE---------------- MLBr_01987|M.leprae_Br4923 AMAFSSFFVVSNS---LRLRNFGAILSCGTSRHRTVKRWRCPPPTRLRST MAV_5246|M.avium_104 AMALSSVLVVGNS---LRLRSFASIIPGA--------------------- TH_2531|M.thermoresistible__bu ILMSLSTVVVALN---AQLLRRLDLRPEQSLAAARR-------------- : : MMAR_2275|M.marinum_M ------------------------- MUL_1477|M.ulcerans_Agy99 ------------------------- Mb1504|M.bovis_AF2122/97 ------------------------- Rv1469|M.tuberculosis_H37Rv ------------------------- MSMEG_5403|M.smegmatis_MC2_155 ------------------------- Mvan_3729|M.vanbaalenii_PYR-1 ------------------------- Mflv_2822|M.gilvum_PYR-GCK ------------------------- MAB_4853c|M.abscessus_ATCC_199 ------------------------- MLBr_01987|M.leprae_Br4923 ACSPVDASPLRPVAHRTGVKPPTHR MAV_5246|M.avium_104 ------------------------- TH_2531|M.thermoresistible__bu -------------------------