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VRVCAGIVVRVSADLQAADWERTTATGEEVRGWRAPRSSAWSLPEVRWALIATVLFVVGGLAQLVGAPPW LYWTLYLACYVTGGWEPGWAGLQALRDKTLDVDLLMVAAAIGAAAIGQVFDGALLIVIFATSGALEAVAT KRTEDSVRGLLDLAPDTATRLTDSGAEEVVDTAVLDVGDVLMIRPGERIGGDGTVVDGASEVDQATITGE PLPVDKATGDEVFAGTVNGTGTLRVRVTRPAADTVIARIIAMVSEASASKAKMQLFIEKIEQRYSIGMVL ATIALFTIPLVLGADLQPTLLRAMTFMIVASPCALVLSTMPPLLSAIANAGRHGVLVKSAVVLEKLSTVT HVAFDKTGTLTEGSPRLVHIRPVPDAAVDDAELLALAAAAENPSEHPLARAIVAAARDAGLTLQPVEDFG STPGHGVRARIGEDLVEVGNPTLLPAVREIAHEMVDDLEQTGHTAVIVRLNGTVVGVLGLTDRVRDAAAD MVAALTELTGAQPILLTGDNPRAAAALAAQVGITDVRAGLLPQDKVEAVRELEAAGAKVMLVGDGVNDAP AMALATVGVAKGRTGSDLALATADAVITRDDLSTIPAVLALARRARRLVIANLTIAATLITVLVAWDLIG HLPLPLGVAGHEGSTIVVGLNGLRLLRDAAWPSTRGTKATAKTGK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3729 | - | - | 100% (675) | heavy metal translocating P-type ATPase |
M. vanbaalenii PYR-1 | Mvan_3700 | - | e-111 | 38.15% (637) | heavy metal translocating P-type ATPase |
M. vanbaalenii PYR-1 | Mvan_5411 | - | e-106 | 37.32% (635) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1504 | ctpD | 0.0 | 60.71% (644) | cation transporter P-type ATPase D |
M. gilvum PYR-GCK | Mflv_2822 | - | 1e-111 | 37.83% (637) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv1469 | ctpD | 0.0 | 60.71% (644) | cation transporter P-type ATPase D |
M. leprae Br4923 | MLBr_00747 | ctpC | 1e-78 | 32.70% (633) | putative cation transport ATPase |
M. abscessus ATCC 19977 | MAB_4853c | - | 1e-107 | 38.57% (630) | cation-transporting ATPase G |
M. marinum M | MMAR_2275 | ctpD | 0.0 | 61.15% (641) | cation transporter p-type ATPase D CtpD |
M. avium 104 | MAV_5246 | - | 6e-79 | 38.63% (554) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5403 | cadA | 0.0 | 62.15% (634) | cadmium-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_2531 | - | 3e-86 | 36.10% (651) | PUTATIVE copper-translocating P-type ATPase |
M. ulcerans Agy99 | MUL_1477 | ctpD | 0.0 | 60.84% (641) | cation transporter p-type ATPase D CtpD |
CLUSTAL 2.0.9 multiple sequence alignment Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALD MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5246|M.avium_104 -------------------------------------------------- TH_2531|M.thermoresistible__bu -------------------------------------------------- MLBr_00747|M.leprae_Br4923 -------------------------------------------------- Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK LTDLLPDSDERCADRLTRGLVDDGIIEQAHVIDGDTPKPRLCVHYDAEAA MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5246|M.avium_104 --------------------------------------------MSTPPR TH_2531|M.thermoresistible__bu --------------------------------------------MVGPAH MLBr_00747|M.leprae_Br4923 ----------------------------------------MTLAMAEQIA Mb1504|M.bovis_AF2122/97 -------------------------------------------------- Rv1469|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2275|M.marinum_M -------------------------------------------------- MUL_1477|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5403|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_3729|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2822|M.gilvum_PYR-GCK SATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTALVDTLSTIPGV MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5246|M.avium_104 HIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYA TH_2531|M.thermoresistible__bu HG--------TVAADGRAQHLTGR---------DHHRHGHG--------- MLBr_00747|M.leprae_Br4923 TADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCN-------- Mb1504|M.bovis_AF2122/97 -------------------------------MTLTACEVTAAEAPFDR-- Rv1469|M.tuberculosis_H37Rv -------------------------------MTLTACEVTAAEAPFDR-- MMAR_2275|M.marinum_M -------------------------------MTLTAFEVSAAEASSDRPD MUL_1477|M.ulcerans_Agy99 -------------------------------MTLTAFEVSAAEASSDRSD MSMEG_5403|M.smegmatis_MC2_155 ---------------------------------MTALYPAVEPAPAAR-- Mvan_3729|M.vanbaalenii_PYR-1 --------------------------MRVCAGIVVRVSADLQAADWERTT Mflv_2822|M.gilvum_PYR-GCK VAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHD-- MAB_4853c|M.abscessus_ATCC_199 -------------------------------MSDACGCGHDEPATGDE-- MAV_5246|M.avium_104 TEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPRDDPELASLRRRLV TH_2531|M.thermoresistible__bu ---------------------DHAGHVAEFRR--------LFWVMLLLAV MLBr_00747|M.leprae_Br4923 -------------GVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAH Mb1504|M.bovis_AF2122/97 -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW Rv1469|M.tuberculosis_H37Rv -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW MMAR_2275|M.marinum_M RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW MUL_1477|M.ulcerans_Agy99 RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW MSMEG_5403|M.smegmatis_MC2_155 -----PARPRS-GGWLWTVPSVRWAAAALALFLTG-LAAQLLGAPQAVVW Mvan_3729|M.vanbaalenii_PYR-1 ATGEEVRGWRAPRSSAWSLPEVRWALIATVLFVVG-GLAQLVGAPPWLYW Mflv_2822|M.gilvum_PYR-GCK --GDGADHQHGHGGISGERTELVFAGLAGALLLTGWLLAAFADTPRSAEV MAB_4853c|M.abscessus_ATCC_199 --VDGEREPERLWEVS----ELRFAAVAGVVLLAGYVVG-WTGGSHPVEI MAV_5246|M.avium_104 TAIALAG----PVIAVAMIPALQFQHWHWAALALTAPVVGWCGRPFHAAA TH_2531|M.thermoresistible__bu PTVAFSG----MFAMILGYQVPRVPGAQWVSPVLGTVMYVWGGRPFLTGA MLBr_00747|M.leprae_Br4923 VAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTT Mb1504|M.bovis_AF2122/97 TLYLACYLAGGWGSAWAGAQALRNKALD-------------------VDL Rv1469|M.tuberculosis_H37Rv TLYLACYLAGGWGSAWAGAQALRNKALD-------------------VDL MMAR_2275|M.marinum_M TLYLACYLAGGWGSAWAGAQALRNRALD-------------------VDL MUL_1477|M.ulcerans_Agy99 TLYLACYLAGGWGSAWAGAQALRNRALD-------------------VDL MSMEG_5403|M.smegmatis_MC2_155 TLYLACYVVGGWEPAWVGVRALRNRTLD-------------------VDL Mvan_3729|M.vanbaalenii_PYR-1 TLYLACYVTGGWEPGWAGLQALRDKTLD-------------------VDL Mflv_2822|M.gilvum_PYR-GCK VVYGLAFFFGAFFTVQEAFASVRQGRFE-------------------IDF MAB_4853c|M.abscessus_ATCC_199 GLYAAALAIGAYTFVPSTLRRLARGKIG-------------------VGT MAV_5246|M.avium_104 WANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGH TH_2531|M.thermoresistible__bu ISEIRSRTPGMMLLIGLALTVAFLSS-----------------------W MLBr_00747|M.leprae_Br4923 SRLVASGVTIFTGYPFLRGALRFGKTG--------------------TDA Mb1504|M.bovis_AF2122/97 LMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLA Rv1469|M.tuberculosis_H37Rv LMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLA MMAR_2275|M.marinum_M LMIVAAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADSVKGLLDLA MUL_1477|M.ulcerans_Agy99 LMIVAAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADSVKGLLDLA MSMEG_5403|M.smegmatis_MC2_155 LMIVAAIGAATIGQVFDGALLIVIFATSGALEDVATTRTERSVRGLLDLA Mvan_3729|M.vanbaalenii_PYR-1 LMVAAAIGAAAIGQVFDGALLIVIFATSGALEAVATKRTEDSVRGLLDLA Mflv_2822|M.gilvum_PYR-GCK LMLVSAAGAAALGEVAEGALLLFLFSVGHALEGYAMGRARRAIEALAELA MAB_4853c|M.abscessus_ATCC_199 LMTIAAIGAVILGEVGEAAMLAFLFSISEGLEEYALARTRRGLRALLSLA MAV_5246|M.avium_104 GAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALG TH_2531|M.thermoresistible__bu GASLGVLDHRLEFWWELALLIVIMLLG-HWIELRSLARTTSALDSLAALL MLBr_00747|M.leprae_Br4923 LVSAATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRAISALLSGT . . : :. :: : : .: .* Mb1504|M.bovis_AF2122/97 PDQA-VVVQGDG---SERVVAASELVVGDRVVVRPGDRIPADGAVLSGAS Rv1469|M.tuberculosis_H37Rv PDQA-VVVQGDG---SERVVAASELVVGDRVVVRPGDRIPADGAVLSGAS MMAR_2275|M.marinum_M PEQA-TVFDVDG---NEQVVAASELVVGDRVVVRPGERIPADGAVLSGCS MUL_1477|M.ulcerans_Agy99 PEQA-TVFDVDG---NEQVVAASELVVGDRVVVRPGERIPADGAVLSGCS MSMEG_5403|M.smegmatis_MC2_155 PEHA-TLLG-DG---SQRVVAAADLRPGDVIVVRPGERISADGTVIGGAS Mvan_3729|M.vanbaalenii_PYR-1 PDTA-TRLTDSG---AEEVVDTAVLDVGDVLMIRPGERIGGDGTVVDGAS Mflv_2822|M.gilvum_PYR-GCK PKTALVRRGGTG---DTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSS MAB_4853c|M.abscessus_ATCC_199 PEEATVLRDGT-----ETTITATELQVGDTMLVRPGERVATDGTITAGRT MAV_5246|M.avium_104 AKDVAV-LRAG----AETRIPIERLAVGDEFVVRPGERIATDGIVVAGSS TH_2531|M.thermoresistible__bu PDTAER-VEQGPDGETVTVVAPADLRVGDTVIVRPGAGIPADGRIIDGVA MLBr_00747|M.leprae_Br4923 QDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVDGEVIDGEA . . : : ** .::: : ** : * : Mb1504|M.bovis_AF2122/97 DVDQRSITGESMPVAKARG----------------DEVFAGTVNGSGVLH Rv1469|M.tuberculosis_H37Rv DVDQRSITGESMPVAKARG----------------DEVFAGTVNGSGVLH MMAR_2275|M.marinum_M EVDQCSITGESMPAAKGRG----------------DEVFAGTVNGSGVLQ MUL_1477|M.ulcerans_Agy99 EVDQCSIAGESMPAAKGRG----------------DEVFAGTVNGSGVLQ MSMEG_5403|M.smegmatis_MC2_155 EVDQSSITGEPLPAAKDVG----------------DDVFAGTVNGSGALR Mvan_3729|M.vanbaalenii_PYR-1 EVDQATITGEPLPVDKATG----------------DEVFAGTVNGTGTLR Mflv_2822|M.gilvum_PYR-GCK SIDQAPVTGESVPVDKIPVPDVAAAAASPELIDAASRVFAGTINGAGAIE MAB_4853c|M.abscessus_ATCC_199 ALNTSAITGESVPVEAGPG----------------DEVFAGSINGNGVLQ MAV_5246|M.avium_104 AVDAAMLTGESVPVEVGVG----------------DGVTGGTVNAGGRLV TH_2531|M.thermoresistible__bu DVDESMVTGESVPVRRGVG----------------DRVVAATVATDSGLR MLBr_00747|M.leprae_Br4923 VVNQSAITGENLPVSVMAG----------------SHVHAGSVVVRGRLM :: ::** :*. . * ..:: . : Mb1504|M.bovis_AF2122/97 LVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLA Rv1469|M.tuberculosis_H37Rv LVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLA MMAR_2275|M.marinum_M LLVTRDPSQTVVARIVELVSEASATKAKTQLFIEKIEQRYSIGVVIATLA MUL_1477|M.ulcerans_Agy99 LLVTRDPSQTVVARIVERVSEASATKAKTQLFIEKIEQRYSIGVVIATLA MSMEG_5403|M.smegmatis_MC2_155 VEVTREPSQTVVARIVAMVTEASATKATTQLFIEKIEQRYSAGVVVATLA Mvan_3729|M.vanbaalenii_PYR-1 VRVTRPAADTVIARIIAMVSEASASKAKMQLFIEKIEQRYSIGMVLATIA Mflv_2822|M.gilvum_PYR-GCK IQVTRLASDSTLARVVRLVAEAQTKTTSTQRFTDRFQRIFVPVVLVGVVL MAB_4853c|M.abscessus_ATCC_199 VRVSATAADNSLARIVAIVEAEQSRKGASQRLADRIAKPLVPAIMITAAA MAV_5246|M.avium_104 VRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVA TH_2531|M.thermoresistible__bu ITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADTAAGWLFWFALGAALL MLBr_00747|M.leprae_Br4923 VRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAI : .: .. :. : * . * . : . Mb1504|M.bovis_AF2122/97 LIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG Rv1469|M.tuberculosis_H37Rv LIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG MMAR_2275|M.marinum_M LIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG MUL_1477|M.ulcerans_Agy99 LIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSAIADAGRHG MSMEG_5403|M.smegmatis_MC2_155 LLTVPLMFGADLRSTLLRAMTFMIVASPCAVVLATMPPLLSAIANASRHG Mvan_3729|M.vanbaalenii_PYR-1 LFTIPLVLGADLQPTLLRAMTFMIVASPCALVLSTMPPLLSAIANAGRHG Mflv_2822|M.gilvum_PYR-GCK LLFAGFVVDEPFTDTVYRALAVLVAASPCALAIATPSAVLSAVARAARAG MAB_4853c|M.abscessus_ATCC_199 IAVLGSVFGDPLV-WIERALVVLVAASPCALAISVPVTVVAAIGAASKLG MAV_5246|M.avium_104 TLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLG TH_2531|M.thermoresistible__bu TALVWAVLH-RPDFAVVRTITVLVIACPHALGLAIPLVVAIATERAARGG MLBr_00747|M.leprae_Br4923 TLAITKDVR--------RTMTVLLIACPCAVGLATPTAISAAIGNGARRG ::..:: *.* *: :: : . ..: * Mb1504|M.bovis_AF2122/97 VLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLL Rv1469|M.tuberculosis_H37Rv VLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLL MMAR_2275|M.marinum_M VLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLSVDVG-IKKLL MUL_1477|M.ulcerans_Agy99 VLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLSADVG-IKKLL MSMEG_5403|M.smegmatis_MC2_155 VLVKSAVAMERLADTDVVVLDKTGTLTAGEPVISRVTVLIDGAD----VL Mvan_3729|M.vanbaalenii_PYR-1 VLVKSAVVLEKLSTVTHVAFDKTGTLTEGSPRLVHIRPVPDAAVDDAELL Mflv_2822|M.gilvum_PYR-GCK ILMKGGAALEELGRVNVLAFDKTGTLTEGRPRIADVCATADSDD--AELL MAB_4853c|M.abscessus_ATCC_199 VLVKGGAALEALGVVRTIALDKTGTLTANRPTVIEVAATAGATG--ERVL MAV_5246|M.avium_104 VLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGTDR--ATLL TH_2531|M.thermoresistible__bu VLIKDRIALENMRTVDVVLFDKTGTLTKGQPAVTGITAAGAHSE--EDVL MLBr_00747|M.leprae_Br4923 ILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSP-EQVL :*:*. :* . : :*****:* . : : :* Mb1504|M.bovis_AF2122/97 QLAAAAEQSSEHPLGRAIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVG Rv1469|M.tuberculosis_H37Rv QLAAAAEQSSEHPLGRAIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVG MMAR_2275|M.marinum_M QLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPGRGVRASVG MUL_1477|M.ulcerans_Agy99 QLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPGRGVRASVG MSMEG_5403|M.smegmatis_MC2_155 GMAAAAEQFSEHPLGRAIVAAA--RGR--VVPEAGDFTALPGRGVRARVA Mvan_3729|M.vanbaalenii_PYR-1 ALAAAAENPSEHPLARAIVAAA--RDAGLTLQPVEDFGSTPGHGVRARIG Mflv_2822|M.gilvum_PYR-GCK RIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRATDVRAVIGRGIVASVE MAB_4853c|M.abscessus_ATCC_199 SAAAALESRSEHPLAAAILAA-----AGSVDP-ADDVEAVTSAGLTGRRG MAV_5246|M.avium_104 RYAGALEAASEHPIAHAIARDA--KAELGPLPTPTGFRAVGGGGVHGRVD TH_2531|M.thermoresistible__bu RLAAAAEAPSEHPLARALVAAA--QRHGTDLPPATDFASTPGLGVRARVA MLBr_00747|M.leprae_Br4923 AYAASSEIHSRHPLAEAVIRST--EERHISIPPHEECEVLVGLGMRTWAD * : * * **:. *: . *: Mb1504|M.bovis_AF2122/97 NDFVEIASPQSYRG-------APLAELAPLLSAGATAAIVLLDGVAIGVL Rv1469|M.tuberculosis_H37Rv NDFVEIASPQSYRG-------APLAELAPLLSAGATAAIVLLDGVAIGVL MMAR_2275|M.marinum_M REFVEVCSPHSYRG-------APLPELAPILEAGATAAIVLRNGVAIGVL MUL_1477|M.ulcerans_Agy99 REFVEVCSPHSYRG-------APLPELAPILEAGATAAIVLRNGVAIGVL MSMEG_5403|M.smegmatis_MC2_155 GHVVEVVSPAAYAGE----NAAVREHCAAIENDGGTAVVVLEDGLPVGVI Mvan_3729|M.vanbaalenii_PYR-1 EDLVEVGNPTLLPAV----REIAHEMVDDLEQTGHTAVIVRLNGTVVGVL Mflv_2822|M.gilvum_PYR-GCK GVEVCIGKTELFTDAAQPPPAELAAEVNRLEQAGRTTMLVRAGDRWLGAI MAB_4853c|M.abscessus_ATCC_199 GHTLRLGRPGWID------PGSLAPDVARMQQGGATAVLVEEDGQLLGAI MAV_5246|M.avium_104 GHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGIL TH_2531|M.thermoresistible__bu GRTVRVGGPRLLAETGQTAPAGSEGWRAR----GSTVLYVLVDDMIAGAV MLBr_00747|M.leprae_Br4923 GRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLI : : . * . .. * : Mb1504|M.bovis_AF2122/97 GLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRA Rv1469|M.tuberculosis_H37Rv GLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRA MMAR_2275|M.marinum_M GLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRA MUL_1477|M.ulcerans_Agy99 GLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRA MSMEG_5403|M.smegmatis_MC2_155 GLADRLRPDAPAAVMQLAQLTKHPPMLLTGDNRRAAGRLAEEAGIADVHA Mvan_3729|M.vanbaalenii_PYR-1 GLTDRVRDAAADMVAALTELTGAQPILLTGDNPRAAAALAAQVGITDVRA Mflv_2822|M.gilvum_PYR-GCK GLMDLPRPEASAVIARLAALGVKNTVMLSGDNQRVADAVAAEVGVAHARG MAB_4853c|M.abscessus_ATCC_199 AVRDELRPEAAHVIAALHRSGYR-VAMLTGDNAATATTLARQVGIDTVHA MAV_5246|M.avium_104 ALADTVKPSSAAAVRQFTRLGLT-PILLTGDNHTVARRTAGELGIGEVIS TH_2531|M.thermoresistible__bu ALADEIRPESRPTVDALHRQGID-VALITGDARSVAESVAAELGIDRVLA MLBr_00747|M.leprae_Br4923 SLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRA .: * : : : : :::** * * . *: . Mb1504|M.bovis_AF2122/97 ALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADL Rv1469|M.tuberculosis_H37Rv ALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADL MMAR_2275|M.marinum_M ALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADL MUL_1477|M.ulcerans_Agy99 ALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADP MSMEG_5403|M.smegmatis_MC2_155 ELLPDGKAAAVQKLQRDNTHVLVVGDGVNDAPAMAAAHTSIAMGRAGADL Mvan_3729|M.vanbaalenii_PYR-1 GLLPQDKVEAVRELEAAGAKVMLVGDGVNDAPAMALATVGVAKGRTGSDL Mflv_2822|M.gilvum_PYR-GCK DLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGASVGIAMGAAGSDV MAB_4853c|M.abscessus_ATCC_199 DLRPEDKARIITELRQQHP-TAMVGDGVNDAPALATADLGIAMGAMGTDV MAV_5246|M.avium_104 GALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMG-TGTDV TH_2531|M.thermoresistible__bu DVPPEHKAAKVVELQREGRRVAMVGDGVNDAPALARADVGIAIG-AGTDV MLBr_00747|M.leprae_Br4923 EVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDV * * : *. . :********.*:* * .:* * *:* Mb1504|M.bovis_AF2122/97 TLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDL Rv1469|M.tuberculosis_H37Rv TLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDL MMAR_2275|M.marinum_M TLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGTFISVLVLWDL MUL_1477|M.ulcerans_Agy99 TLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGTFISVLVLWDL MSMEG_5403|M.smegmatis_MC2_155 TVQTADVVTIRDELATVPAVIALARRARRVVIANLVMAGAAITTLVLWDL Mvan_3729|M.vanbaalenii_PYR-1 ALATADAVITRDDLSTIPAVLALARRARRLVIANLTIAATLITVLVAWDL Mflv_2822|M.gilvum_PYR-GCK ALETADVALMADDLRALPFAISLSRRSSRVIKQNLWASLGIVAVLIPATI MAB_4853c|M.abscessus_ATCC_199 AIETADVALMGEDLRHLTQALAHARRARTIMLQNVGLSLALIAVLIPLAL MAV_5246|M.avium_104 AIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAA TH_2531|M.thermoresistible__bu AIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWWAAGYNLIAVPLAA MLBr_00747|M.leprae_Br4923 AVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGA :: :*. . : . : : * : : Mb1504|M.bovis_AF2122/97 FGQLPLPLGVVGHEGSTVLVALNGMRL-----LTNRSWRAAASAAR---- Rv1469|M.tuberculosis_H37Rv FGQLPLPLGVVGHEGSTVLVALNGMRL-----LTNRSWRAAASAAR---- MMAR_2275|M.marinum_M FGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRAAASPVR---- MUL_1477|M.ulcerans_Agy99 FGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRAAASPVR---- MSMEG_5403|M.smegmatis_MC2_155 FGQLPLPLGVAGHEGSTILVALNGLRL-----LSNRAWISPGATPT---- Mvan_3729|M.vanbaalenii_PYR-1 IGHLPLPLGVAGHEGSTIVVGLNGLRL-----LRDAAWPSTRGTKATAKT Mflv_2822|M.gilvum_PYR-GCK FG-LGIGPAVLIHEGSTLIVVANALRL-----LGMPMQSVTPAAPRVERA MAB_4853c|M.abscessus_ATCC_199 LGILGLAAVVAVHELAEIVVIANGVRAGRTQPLTAPEHANTPAAQLAQQE MAV_5246|M.avium_104 -----LGMLNPMLAGAA-MALSSVLVVGNS-----LRLRSFASIIPGA-- TH_2531|M.thermoresistible__bu GVLAPAGFVMPMSVGAILMSLSTVVVALNAQLLRRLDLRPEQSLAAARR- MLBr_00747|M.leprae_Br4923 G-----GALSPVLAAVLHNASSVAVVANSS---RLIRYRLD--------- : Mb1504|M.bovis_AF2122/97 ---- Rv1469|M.tuberculosis_H37Rv ---- MMAR_2275|M.marinum_M ---- MUL_1477|M.ulcerans_Agy99 ---- MSMEG_5403|M.smegmatis_MC2_155 ---- Mvan_3729|M.vanbaalenii_PYR-1 GK-- Mflv_2822|M.gilvum_PYR-GCK EETP MAB_4853c|M.abscessus_ATCC_199 ---- MAV_5246|M.avium_104 ---- TH_2531|M.thermoresistible__bu ---- MLBr_00747|M.leprae_Br4923 ----