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M. vanbaalenii PYR-1 Mvan_3729 (-)

annotation: heavy metal translocating P-type ATPase
coordinates: 3963376 - 3965403
length: 675

VRVCAGIVVRVSADLQAADWERTTATGEEVRGWRAPRSSAWSLPEVRWALIATVLFVVGGLAQLVGAPPW
LYWTLYLACYVTGGWEPGWAGLQALRDKTLDVDLLMVAAAIGAAAIGQVFDGALLIVIFATSGALEAVAT
KRTEDSVRGLLDLAPDTATRLTDSGAEEVVDTAVLDVGDVLMIRPGERIGGDGTVVDGASEVDQATITGE
PLPVDKATGDEVFAGTVNGTGTLRVRVTRPAADTVIARIIAMVSEASASKAKMQLFIEKIEQRYSIGMVL
ATIALFTIPLVLGADLQPTLLRAMTFMIVASPCALVLSTMPPLLSAIANAGRHGVLVKSAVVLEKLSTVT
HVAFDKTGTLTEGSPRLVHIRPVPDAAVDDAELLALAAAAENPSEHPLARAIVAAARDAGLTLQPVEDFG
STPGHGVRARIGEDLVEVGNPTLLPAVREIAHEMVDDLEQTGHTAVIVRLNGTVVGVLGLTDRVRDAAAD
MVAALTELTGAQPILLTGDNPRAAAALAAQVGITDVRAGLLPQDKVEAVRELEAAGAKVMLVGDGVNDAP
AMALATVGVAKGRTGSDLALATADAVITRDDLSTIPAVLALARRARRLVIANLTIAATLITVLVAWDLIG
HLPLPLGVAGHEGSTIVVGLNGLRLLRDAAWPSTRGTKATAKTGK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3729--100% (675)heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_3700-e-11138.15% (637) heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_5411-e-10637.32% (635) heavy metal translocating P-type ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1504ctpD0.060.71% (644) cation transporter P-type ATPase D
M. gilvum PYR-GCKMflv_2822-1e-11137.83% (637) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv1469ctpD0.060.71% (644) cation transporter P-type ATPase D
M. leprae Br4923MLBr_00747ctpC1e-7832.70% (633) putative cation transport ATPase
M. abscessus ATCC 19977MAB_4853c-1e-10738.57% (630) cation-transporting ATPase G
M. marinum MMMAR_2275ctpD0.061.15% (641) cation transporter p-type ATPase D CtpD
M. avium 104MAV_5246-6e-7938.63% (554) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5403cadA0.062.15% (634) cadmium-translocating P-type ATPase
M. thermoresistible (build 8)TH_2531-3e-8636.10% (651) PUTATIVE copper-translocating P-type ATPase
M. ulcerans Agy99MUL_1477ctpD0.060.84% (641) cation transporter p-type ATPase D CtpD

CLUSTAL 2.0.9 multiple sequence alignment


Mb1504|M.bovis_AF2122/97            --------------------------------------------------
Rv1469|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2275|M.marinum_M               --------------------------------------------------
MUL_1477|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK          MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALD
MAB_4853c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5246|M.avium_104                --------------------------------------------------
TH_2531|M.thermoresistible__bu      --------------------------------------------------
MLBr_00747|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1504|M.bovis_AF2122/97            --------------------------------------------------
Rv1469|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2275|M.marinum_M               --------------------------------------------------
MUL_1477|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK          LTDLLPDSDERCADRLTRGLVDDGIIEQAHVIDGDTPKPRLCVHYDAEAA
MAB_4853c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5246|M.avium_104                --------------------------------------------MSTPPR
TH_2531|M.thermoresistible__bu      --------------------------------------------MVGPAH
MLBr_00747|M.leprae_Br4923          ----------------------------------------MTLAMAEQIA
                                                                                      

Mb1504|M.bovis_AF2122/97            --------------------------------------------------
Rv1469|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2275|M.marinum_M               --------------------------------------------------
MUL_1477|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5403|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3729|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK          SATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTALVDTLSTIPGV
MAB_4853c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5246|M.avium_104                HIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYA
TH_2531|M.thermoresistible__bu      HG--------TVAADGRAQHLTGR---------DHHRHGHG---------
MLBr_00747|M.leprae_Br4923          TADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCN--------
                                                                                      

Mb1504|M.bovis_AF2122/97            -------------------------------MTLTACEVTAAEAPFDR--
Rv1469|M.tuberculosis_H37Rv         -------------------------------MTLTACEVTAAEAPFDR--
MMAR_2275|M.marinum_M               -------------------------------MTLTAFEVSAAEASSDRPD
MUL_1477|M.ulcerans_Agy99           -------------------------------MTLTAFEVSAAEASSDRSD
MSMEG_5403|M.smegmatis_MC2_155      ---------------------------------MTALYPAVEPAPAAR--
Mvan_3729|M.vanbaalenii_PYR-1       --------------------------MRVCAGIVVRVSADLQAADWERTT
Mflv_2822|M.gilvum_PYR-GCK          VAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHD--
MAB_4853c|M.abscessus_ATCC_199      -------------------------------MSDACGCGHDEPATGDE--
MAV_5246|M.avium_104                TEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPRDDPELASLRRRLV
TH_2531|M.thermoresistible__bu      ---------------------DHAGHVAEFRR--------LFWVMLLLAV
MLBr_00747|M.leprae_Br4923          -------------GVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAH
                                                                                      

Mb1504|M.bovis_AF2122/97            -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW
Rv1469|M.tuberculosis_H37Rv         -VSKTIPHPLSWGAALWSVVSVRWATVALLLFLAG-LVAQLNGAPEAMWW
MMAR_2275|M.marinum_M               RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW
MUL_1477|M.ulcerans_Agy99           RIPSTSVRPLTWRAALWSVMSVRWAGIALALFLTG-LVAQLNGAAEPVWW
MSMEG_5403|M.smegmatis_MC2_155      -----PARPRS-GGWLWTVPSVRWAAAALALFLTG-LAAQLLGAPQAVVW
Mvan_3729|M.vanbaalenii_PYR-1       ATGEEVRGWRAPRSSAWSLPEVRWALIATVLFVVG-GLAQLVGAPPWLYW
Mflv_2822|M.gilvum_PYR-GCK          --GDGADHQHGHGGISGERTELVFAGLAGALLLTGWLLAAFADTPRSAEV
MAB_4853c|M.abscessus_ATCC_199      --VDGEREPERLWEVS----ELRFAAVAGVVLLAGYVVG-WTGGSHPVEI
MAV_5246|M.avium_104                TAIALAG----PVIAVAMIPALQFQHWHWAALALTAPVVGWCGRPFHAAA
TH_2531|M.thermoresistible__bu      PTVAFSG----MFAMILGYQVPRVPGAQWVSPVLGTVMYVWGGRPFLTGA
MLBr_00747|M.leprae_Br4923          VAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTT
                                                                                      

Mb1504|M.bovis_AF2122/97            TLYLACYLAGGWGSAWAGAQALRNKALD-------------------VDL
Rv1469|M.tuberculosis_H37Rv         TLYLACYLAGGWGSAWAGAQALRNKALD-------------------VDL
MMAR_2275|M.marinum_M               TLYLACYLAGGWGSAWAGAQALRNRALD-------------------VDL
MUL_1477|M.ulcerans_Agy99           TLYLACYLAGGWGSAWAGAQALRNRALD-------------------VDL
MSMEG_5403|M.smegmatis_MC2_155      TLYLACYVVGGWEPAWVGVRALRNRTLD-------------------VDL
Mvan_3729|M.vanbaalenii_PYR-1       TLYLACYVTGGWEPGWAGLQALRDKTLD-------------------VDL
Mflv_2822|M.gilvum_PYR-GCK          VVYGLAFFFGAFFTVQEAFASVRQGRFE-------------------IDF
MAB_4853c|M.abscessus_ATCC_199      GLYAAALAIGAYTFVPSTLRRLARGKIG-------------------VGT
MAV_5246|M.avium_104                WANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGH
TH_2531|M.thermoresistible__bu      ISEIRSRTPGMMLLIGLALTVAFLSS-----------------------W
MLBr_00747|M.leprae_Br4923          SRLVASGVTIFTGYPFLRGALRFGKTG--------------------TDA
                                                                                      

Mb1504|M.bovis_AF2122/97            LMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLA
Rv1469|M.tuberculosis_H37Rv         LMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLA
MMAR_2275|M.marinum_M               LMIVAAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADSVKGLLDLA
MUL_1477|M.ulcerans_Agy99           LMIVAAIGAVAIGQIFDGALLIVIFATSGALDDVATKHTADSVKGLLDLA
MSMEG_5403|M.smegmatis_MC2_155      LMIVAAIGAATIGQVFDGALLIVIFATSGALEDVATTRTERSVRGLLDLA
Mvan_3729|M.vanbaalenii_PYR-1       LMVAAAIGAAAIGQVFDGALLIVIFATSGALEAVATKRTEDSVRGLLDLA
Mflv_2822|M.gilvum_PYR-GCK          LMLVSAAGAAALGEVAEGALLLFLFSVGHALEGYAMGRARRAIEALAELA
MAB_4853c|M.abscessus_ATCC_199      LMTIAAIGAVILGEVGEAAMLAFLFSISEGLEEYALARTRRGLRALLSLA
MAV_5246|M.avium_104                GAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALG
TH_2531|M.thermoresistible__bu      GASLGVLDHRLEFWWELALLIVIMLLG-HWIELRSLARTTSALDSLAALL
MLBr_00747|M.leprae_Br4923          LVSAATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRAISALLSGT
                                        .            .  :  :.     ::  :   :  .: .*    

Mb1504|M.bovis_AF2122/97            PDQA-VVVQGDG---SERVVAASELVVGDRVVVRPGDRIPADGAVLSGAS
Rv1469|M.tuberculosis_H37Rv         PDQA-VVVQGDG---SERVVAASELVVGDRVVVRPGDRIPADGAVLSGAS
MMAR_2275|M.marinum_M               PEQA-TVFDVDG---NEQVVAASELVVGDRVVVRPGERIPADGAVLSGCS
MUL_1477|M.ulcerans_Agy99           PEQA-TVFDVDG---NEQVVAASELVVGDRVVVRPGERIPADGAVLSGCS
MSMEG_5403|M.smegmatis_MC2_155      PEHA-TLLG-DG---SQRVVAAADLRPGDVIVVRPGERISADGTVIGGAS
Mvan_3729|M.vanbaalenii_PYR-1       PDTA-TRLTDSG---AEEVVDTAVLDVGDVLMIRPGERIGGDGTVVDGAS
Mflv_2822|M.gilvum_PYR-GCK          PKTALVRRGGTG---DTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSS
MAB_4853c|M.abscessus_ATCC_199      PEEATVLRDGT-----ETTITATELQVGDTMLVRPGERVATDGTITAGRT
MAV_5246|M.avium_104                AKDVAV-LRAG----AETRIPIERLAVGDEFVVRPGERIATDGIVVAGSS
TH_2531|M.thermoresistible__bu      PDTAER-VEQGPDGETVTVVAPADLRVGDTVIVRPGAGIPADGRIIDGVA
MLBr_00747|M.leprae_Br4923          QDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVDGEVIDGEA
                                     . .               :    :  ** .:::    :  ** :  * :

Mb1504|M.bovis_AF2122/97            DVDQRSITGESMPVAKARG----------------DEVFAGTVNGSGVLH
Rv1469|M.tuberculosis_H37Rv         DVDQRSITGESMPVAKARG----------------DEVFAGTVNGSGVLH
MMAR_2275|M.marinum_M               EVDQCSITGESMPAAKGRG----------------DEVFAGTVNGSGVLQ
MUL_1477|M.ulcerans_Agy99           EVDQCSIAGESMPAAKGRG----------------DEVFAGTVNGSGVLQ
MSMEG_5403|M.smegmatis_MC2_155      EVDQSSITGEPLPAAKDVG----------------DDVFAGTVNGSGALR
Mvan_3729|M.vanbaalenii_PYR-1       EVDQATITGEPLPVDKATG----------------DEVFAGTVNGTGTLR
Mflv_2822|M.gilvum_PYR-GCK          SIDQAPVTGESVPVDKIPVPDVAAAAASPELIDAASRVFAGTINGAGAIE
MAB_4853c|M.abscessus_ATCC_199      ALNTSAITGESVPVEAGPG----------------DEVFAGSINGNGVLQ
MAV_5246|M.avium_104                AVDAAMLTGESVPVEVGVG----------------DGVTGGTVNAGGRLV
TH_2531|M.thermoresistible__bu      DVDESMVTGESVPVRRGVG----------------DRVVAATVATDSGLR
MLBr_00747|M.leprae_Br4923          VVNQSAITGENLPVSVMAG----------------SHVHAGSVVVRGRLM
                                     ::   ::** :*.                     . * ..::   . : 

Mb1504|M.bovis_AF2122/97            LVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLA
Rv1469|M.tuberculosis_H37Rv         LVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLA
MMAR_2275|M.marinum_M               LLVTRDPSQTVVARIVELVSEASATKAKTQLFIEKIEQRYSIGVVIATLA
MUL_1477|M.ulcerans_Agy99           LLVTRDPSQTVVARIVERVSEASATKAKTQLFIEKIEQRYSIGVVIATLA
MSMEG_5403|M.smegmatis_MC2_155      VEVTREPSQTVVARIVAMVTEASATKATTQLFIEKIEQRYSAGVVVATLA
Mvan_3729|M.vanbaalenii_PYR-1       VRVTRPAADTVIARIIAMVSEASASKAKMQLFIEKIEQRYSIGMVLATIA
Mflv_2822|M.gilvum_PYR-GCK          IQVTRLASDSTLARVVRLVAEAQTKTTSTQRFTDRFQRIFVPVVLVGVVL
MAB_4853c|M.abscessus_ATCC_199      VRVSATAADNSLARIVAIVEAEQSRKGASQRLADRIAKPLVPAIMITAAA
MAV_5246|M.avium_104                VRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVA
TH_2531|M.thermoresistible__bu      ITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADTAAGWLFWFALGAALL
MLBr_00747|M.leprae_Br4923          VRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAI
                                    : .:    .. :. :   *   .      * . :          .     

Mb1504|M.bovis_AF2122/97            LIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG
Rv1469|M.tuberculosis_H37Rv         LIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG
MMAR_2275|M.marinum_M               LIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHG
MUL_1477|M.ulcerans_Agy99           LIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATMPPLLSAIADAGRHG
MSMEG_5403|M.smegmatis_MC2_155      LLTVPLMFGADLRSTLLRAMTFMIVASPCAVVLATMPPLLSAIANASRHG
Mvan_3729|M.vanbaalenii_PYR-1       LFTIPLVLGADLQPTLLRAMTFMIVASPCALVLSTMPPLLSAIANAGRHG
Mflv_2822|M.gilvum_PYR-GCK          LLFAGFVVDEPFTDTVYRALAVLVAASPCALAIATPSAVLSAVARAARAG
MAB_4853c|M.abscessus_ATCC_199      IAVLGSVFGDPLV-WIERALVVLVAASPCALAISVPVTVVAAIGAASKLG
MAV_5246|M.avium_104                TLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLG
TH_2531|M.thermoresistible__bu      TALVWAVLH-RPDFAVVRTITVLVIACPHALGLAIPLVVAIATERAARGG
MLBr_00747|M.leprae_Br4923          TLAITKDVR--------RTMTVLLIACPCAVGLATPTAISAAIGNGARRG
                                                      ::..:: *.* *: ::    :  .   ..: *

Mb1504|M.bovis_AF2122/97            VLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLL
Rv1469|M.tuberculosis_H37Rv         VLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLL
MMAR_2275|M.marinum_M               VLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLSVDVG-IKKLL
MUL_1477|M.ulcerans_Agy99           VLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIVEPLSADVG-IKKLL
MSMEG_5403|M.smegmatis_MC2_155      VLVKSAVAMERLADTDVVVLDKTGTLTAGEPVISRVTVLIDGAD----VL
Mvan_3729|M.vanbaalenii_PYR-1       VLVKSAVVLEKLSTVTHVAFDKTGTLTEGSPRLVHIRPVPDAAVDDAELL
Mflv_2822|M.gilvum_PYR-GCK          ILMKGGAALEELGRVNVLAFDKTGTLTEGRPRIADVCATADSDD--AELL
MAB_4853c|M.abscessus_ATCC_199      VLVKGGAALEALGVVRTIALDKTGTLTANRPTVIEVAATAGATG--ERVL
MAV_5246|M.avium_104                VLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGTDR--ATLL
TH_2531|M.thermoresistible__bu      VLIKDRIALENMRTVDVVLFDKTGTLTKGQPAVTGITAAGAHSE--EDVL
MLBr_00747|M.leprae_Br4923          ILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSP-EQVL
                                    :*:*.   :*    .  : :*****:* .   :  :            :*

Mb1504|M.bovis_AF2122/97            QLAAAAEQSSEHPLGRAIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVG
Rv1469|M.tuberculosis_H37Rv         QLAAAAEQSSEHPLGRAIVAEA--RRRGIAIPPAKDFRAVPGCGVHALVG
MMAR_2275|M.marinum_M               QLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPGRGVRASVG
MUL_1477|M.ulcerans_Agy99           QLAAAAEQSSEHPLGRAIVEEV--RRRGITIPGAEDFRALPGRGVRASVG
MSMEG_5403|M.smegmatis_MC2_155      GMAAAAEQFSEHPLGRAIVAAA--RGR--VVPEAGDFTALPGRGVRARVA
Mvan_3729|M.vanbaalenii_PYR-1       ALAAAAENPSEHPLARAIVAAA--RDAGLTLQPVEDFGSTPGHGVRARIG
Mflv_2822|M.gilvum_PYR-GCK          RIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRATDVRAVIGRGIVASVE
MAB_4853c|M.abscessus_ATCC_199      SAAAALESRSEHPLAAAILAA-----AGSVDP-ADDVEAVTSAGLTGRRG
MAV_5246|M.avium_104                RYAGALEAASEHPIAHAIARDA--KAELGPLPTPTGFRAVGGGGVHGRVD
TH_2531|M.thermoresistible__bu      RLAAAAEAPSEHPLARALVAAA--QRHGTDLPPATDFASTPGLGVRARVA
MLBr_00747|M.leprae_Br4923          AYAASSEIHSRHPLAEAVIRST--EERHISIPPHEECEVLVGLGMRTWAD
                                      * : *  * **:. *:                       . *:     

Mb1504|M.bovis_AF2122/97            NDFVEIASPQSYRG-------APLAELAPLLSAGATAAIVLLDGVAIGVL
Rv1469|M.tuberculosis_H37Rv         NDFVEIASPQSYRG-------APLAELAPLLSAGATAAIVLLDGVAIGVL
MMAR_2275|M.marinum_M               REFVEVCSPHSYRG-------APLPELAPILEAGATAAIVLRNGVAIGVL
MUL_1477|M.ulcerans_Agy99           REFVEVCSPHSYRG-------APLPELAPILEAGATAAIVLRNGVAIGVL
MSMEG_5403|M.smegmatis_MC2_155      GHVVEVVSPAAYAGE----NAAVREHCAAIENDGGTAVVVLEDGLPVGVI
Mvan_3729|M.vanbaalenii_PYR-1       EDLVEVGNPTLLPAV----REIAHEMVDDLEQTGHTAVIVRLNGTVVGVL
Mflv_2822|M.gilvum_PYR-GCK          GVEVCIGKTELFTDAAQPPPAELAAEVNRLEQAGRTTMLVRAGDRWLGAI
MAB_4853c|M.abscessus_ATCC_199      GHTLRLGRPGWID------PGSLAPDVARMQQGGATAVLVEEDGQLLGAI
MAV_5246|M.avium_104                GHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGIL
TH_2531|M.thermoresistible__bu      GRTVRVGGPRLLAETGQTAPAGSEGWRAR----GSTVLYVLVDDMIAGAV
MLBr_00747|M.leprae_Br4923          GRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLI
                                       : :  .                          *   .  ..   * :

Mb1504|M.bovis_AF2122/97            GLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRA
Rv1469|M.tuberculosis_H37Rv         GLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRA
MMAR_2275|M.marinum_M               GLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRA
MUL_1477|M.ulcerans_Agy99           GLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQRVAQHAGITDVRA
MSMEG_5403|M.smegmatis_MC2_155      GLADRLRPDAPAAVMQLAQLTKHPPMLLTGDNRRAAGRLAEEAGIADVHA
Mvan_3729|M.vanbaalenii_PYR-1       GLTDRVRDAAADMVAALTELTGAQPILLTGDNPRAAAALAAQVGITDVRA
Mflv_2822|M.gilvum_PYR-GCK          GLMDLPRPEASAVIARLAALGVKNTVMLSGDNQRVADAVAAEVGVAHARG
MAB_4853c|M.abscessus_ATCC_199      AVRDELRPEAAHVIAALHRSGYR-VAMLTGDNAATATTLARQVGIDTVHA
MAV_5246|M.avium_104                ALADTVKPSSAAAVRQFTRLGLT-PILLTGDNHTVARRTAGELGIGEVIS
TH_2531|M.thermoresistible__bu      ALADEIRPESRPTVDALHRQGID-VALITGDARSVAESVAAELGIDRVLA
MLBr_00747|M.leprae_Br4923          SLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRA
                                    .: *  :  :   :  :         :::**    *   * . *:    .

Mb1504|M.bovis_AF2122/97            ALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADL
Rv1469|M.tuberculosis_H37Rv         ALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMG-AGADL
MMAR_2275|M.marinum_M               ALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADL
MUL_1477|M.ulcerans_Agy99           ALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAAHTSVAMG-AGADP
MSMEG_5403|M.smegmatis_MC2_155      ELLPDGKAAAVQKLQRDNTHVLVVGDGVNDAPAMAAAHTSIAMGRAGADL
Mvan_3729|M.vanbaalenii_PYR-1       GLLPQDKVEAVRELEAAGAKVMLVGDGVNDAPAMALATVGVAKGRTGSDL
Mflv_2822|M.gilvum_PYR-GCK          DLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGASVGIAMGAAGSDV
MAB_4853c|M.abscessus_ATCC_199      DLRPEDKARIITELRQQHP-TAMVGDGVNDAPALATADLGIAMGAMGTDV
MAV_5246|M.avium_104                GALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMG-TGTDV
TH_2531|M.thermoresistible__bu      DVPPEHKAAKVVELQREGRRVAMVGDGVNDAPALARADVGIAIG-AGTDV
MLBr_00747|M.leprae_Br4923          EVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDV
                                       *  *   :  *.     . :********.*:* *  .:* *  *:* 

Mb1504|M.bovis_AF2122/97            TLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDL
Rv1469|M.tuberculosis_H37Rv         TLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDL
MMAR_2275|M.marinum_M               TLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGTFISVLVLWDL
MUL_1477|M.ulcerans_Agy99           TLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFIAGTFISVLVLWDL
MSMEG_5403|M.smegmatis_MC2_155      TVQTADVVTIRDELATVPAVIALARRARRVVIANLVMAGAAITTLVLWDL
Mvan_3729|M.vanbaalenii_PYR-1       ALATADAVITRDDLSTIPAVLALARRARRLVIANLTIAATLITVLVAWDL
Mflv_2822|M.gilvum_PYR-GCK          ALETADVALMADDLRALPFAISLSRRSSRVIKQNLWASLGIVAVLIPATI
MAB_4853c|M.abscessus_ATCC_199      AIETADVALMGEDLRHLTQALAHARRARTIMLQNVGLSLALIAVLIPLAL
MAV_5246|M.avium_104                AIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAA
TH_2531|M.thermoresistible__bu      AIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWWAAGYNLIAVPLAA
MLBr_00747|M.leprae_Br4923          AVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGA
                                    :: :*. .    :          .  :   :  *   :       :    

Mb1504|M.bovis_AF2122/97            FGQLPLPLGVVGHEGSTVLVALNGMRL-----LTNRSWRAAASAAR----
Rv1469|M.tuberculosis_H37Rv         FGQLPLPLGVVGHEGSTVLVALNGMRL-----LTNRSWRAAASAAR----
MMAR_2275|M.marinum_M               FGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRAAASPVR----
MUL_1477|M.ulcerans_Agy99           FGQLPLPLGVAGHEGSTVLVALNGMRL-----LTNRSWRAAASPVR----
MSMEG_5403|M.smegmatis_MC2_155      FGQLPLPLGVAGHEGSTILVALNGLRL-----LSNRAWISPGATPT----
Mvan_3729|M.vanbaalenii_PYR-1       IGHLPLPLGVAGHEGSTIVVGLNGLRL-----LRDAAWPSTRGTKATAKT
Mflv_2822|M.gilvum_PYR-GCK          FG-LGIGPAVLIHEGSTLIVVANALRL-----LGMPMQSVTPAAPRVERA
MAB_4853c|M.abscessus_ATCC_199      LGILGLAAVVAVHELAEIVVIANGVRAGRTQPLTAPEHANTPAAQLAQQE
MAV_5246|M.avium_104                -----LGMLNPMLAGAA-MALSSVLVVGNS-----LRLRSFASIIPGA--
TH_2531|M.thermoresistible__bu      GVLAPAGFVMPMSVGAILMSLSTVVVALNAQLLRRLDLRPEQSLAAARR-
MLBr_00747|M.leprae_Br4923          G-----GALSPVLAAVLHNASSVAVVANSS---RLIRYRLD---------
                                                            :                         

Mb1504|M.bovis_AF2122/97            ----
Rv1469|M.tuberculosis_H37Rv         ----
MMAR_2275|M.marinum_M               ----
MUL_1477|M.ulcerans_Agy99           ----
MSMEG_5403|M.smegmatis_MC2_155      ----
Mvan_3729|M.vanbaalenii_PYR-1       GK--
Mflv_2822|M.gilvum_PYR-GCK          EETP
MAB_4853c|M.abscessus_ATCC_199      ----
MAV_5246|M.avium_104                ----
TH_2531|M.thermoresistible__bu      ----
MLBr_00747|M.leprae_Br4923          ----