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M. leprae Br4923 MLBr_00747 (ctpC)

annotation: putative cation transport ATPase
coordinates: 888802 - 890979
length: 725

TLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCNGVRVVHAYPRTGSVVVWYS
PRCCDRQSILAAISGAAHVAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTTSR
LVASGVTIFTGYPFLRGALRFGKTGTDALVSAATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRA
ISALLSGTQDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVDGEVIDGEAVVNQSAITGENL
PVSVMAGSHVHAGSVVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVS
AITLAITKDVRRTMTVLLIACPCAVGLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTL
TVGRPVVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEERHISIPPHEECEVLVGLGMRTWA
DGRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLISLRDEVRPEAAEVLTKLRA
SGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADI
GIAMGLAGTDVAVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGALSPVLA
AVLHNASSVAVVANSSRLIRYRLD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00747ctpC-100% (725)putative cation transport ATPase
M. leprae Br4923MLBr_01987ctpA2e-8534.66% (655) putative cation-transporting ATPase
M. leprae Br4923MLBr_02000ctpB1e-7834.42% (552) cation-transporting ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3298ctpC0.086.12% (713) metal cation-transporting P-type ATPase C CtpC
M. gilvum PYR-GCKMflv_0912-2e-9333.47% (735) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv3270ctpC0.086.12% (713) metal cation-transporting P-type ATPase C CtpC
M. abscessus ATCC 19977MAB_4853c-2e-9236.54% (583) cation-transporting ATPase G
M. marinum MMMAR_1271ctpC0.085.38% (732) metal cation-transporting p-type ATPase C CtpC
M. avium 104MAV_4235cadA0.084.92% (716) cadmium-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_6058-0.075.81% (711) cadmium transporting P-type ATPase
M. thermoresistible (build 8)TH_4361-7e-9137.94% (601) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_2616ctpC0.084.97% (732) metal cation-transporting p-type ATPase C CtpC
M. vanbaalenii PYR-1Mvan_4449-4e-9534.63% (667) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3298|M.bovis_AF2122/97            ------------------MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEE
Rv3270|M.tuberculosis_H37Rv         ------------------MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEE
MMAR_1271|M.marinum_M               MTLAIVKEVPAGADGDDTTDLVVLSDAAGRMRVRADWVRGNSRRAVAVEE
MUL_2616|M.ulcerans_Agy99           MTLAIVKEVPAGADGDDTTDLVVLSDAAGRMRVRADWVRGNSRRAVAVEE
MAV_4235|M.avium_104                ---------------MEDPALQVISDAAGRMRVSVGWVRADSRRAVAVEE
MLBr_00747|M.leprae_Br4923          MTLAMAEQIAT----ADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEE
MSMEG_6058|M.smegmatis_MC2_155      -----------------MADLTVVSDAAGRMRVHAPWFRGDAVRAVAIEQ
Mflv_0912|M.gilvum_PYR-GCK          --MALMTTSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVAATVN
Mvan_4449|M.vanbaalenii_PYR-1       -----MNT----------IELSIGGMTCASCAARVEKKLNKLDGVTATVN
TH_4361|M.thermoresistible__bu      -----MNTGGMN-----TVTLTVGGMTCASCAARVEKRLNRIDGVVATVN
MAB_4853c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3298|M.bovis_AF2122/97            AVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIP
Rv3270|M.tuberculosis_H37Rv         AVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIP
MMAR_1271|M.marinum_M               AVAKQDGVRVVHAYPRTGSVVVWYSPRRCDRAAVLEAIGGAKHVAAELIP
MUL_2616|M.ulcerans_Agy99           AVAKQDGVRVVHAYPRTGSVVVWYSPRRCDRAAVLEAIGGAKHVAAELIP
MAV_4235|M.avium_104                AVAKCDGVRVVHAYPRTGSVVIWYSPRRCDRSAVLAAIGEAAHVAAELIP
MLBr_00747|M.leprae_Br4923          AIAKCNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIP
MSMEG_6058|M.smegmatis_MC2_155      AVDQVPGVRAVHAYPRTGSVVVWYSPRRCDRDAVRSAMTAAAGVARHLVP
Mflv_0912|M.gilvum_PYR-GCK          YATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGDTPNA
Mvan_4449|M.vanbaalenii_PYR-1       FATEKARVAFGDEVSPGQLVSAVESAGYQAELPE-RPDEPAEPT------
TH_4361|M.thermoresistible__bu      FATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGAATGA
MAB_4853c|M.abscessus_ATCC_199      ---------------------MSDACGCGHDEPATGDEVDGERE------
                                                                    .       .         

Mb3298|M.bovis_AF2122/97            ARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATG
Rv3270|M.tuberculosis_H37Rv         ARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATG
MMAR_1271|M.marinum_M               ARAPHSTEIRNTDVLRMVIGGAALALLGVRRYVFARPPLLGPSGRMVATG
MUL_2616|M.ulcerans_Agy99           AHAPHSTEIRNTDVLRMVIGGAALALLGVRRYVFARPPLLGPSGRMVATG
MAV_4235|M.avium_104                ARAPHSSEIRNADVLRMVIGGAALALLGVRRYVFARPPLLGPSGRLFATG
MLBr_00747|M.leprae_Br4923          TRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTTSRLVASG
MSMEG_6058|M.smegmatis_MC2_155      GRSPRSADVHNADIVRMAIGAVALILLGIRRYGFARPPLLGSTSRTLATG
Mflv_0912|M.gilvum_PYR-GCK          D-GIDDPELASLRHRLRASTVLTVPVIAMAMIPALQFTYWQWASLTLAAP
Mvan_4449|M.vanbaalenii_PYR-1       ----DDP-TAALKRRLLICVALSVPVIAMAMVPVLQFTYWQWLSLTLAAP
TH_4361|M.thermoresistible__bu      AGDDHDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLALTLTSP
MAB_4853c|M.abscessus_ATCC_199      --------PERLWEVSELRFAAVAGVVLLAGYVVGWTGGSHPVEIGLYAA
                                                             :: :                 . : 

Mb3298|M.bovis_AF2122/97            VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATVASLILR----------
Rv3270|M.tuberculosis_H37Rv         VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATVASLILR----------
MMAR_1271|M.marinum_M               VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATIASLILR----------
MUL_2616|M.ulcerans_Agy99           VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATIASLILR----------
MAV_4235|M.avium_104                VTVFTGYPFLRGALRSLRSGRAG-TDALVSAATVASLVLR----------
MLBr_00747|M.leprae_Br4923          VTIFTGYPFLRGALR---FGKTG-TDALVSAATIASLILR----------
MSMEG_6058|M.smegmatis_MC2_155      ATIITGYPFLRGALRTLTGNRSAGTDVLVSAATVASLVLR----------
Mflv_0912|M.gilvum_PYR-GCK          VIVWAAWPFHRAAWANLRHGTAT-MDTLISLGTVSAFLWSLYALFFGTAG
Mvan_4449|M.vanbaalenii_PYR-1       VVVWGAWPFHQAAWTNLRHGTAT-MDTLISIGTLAALGWSIYALFWGTAG
TH_4361|M.thermoresistible__bu      VVVWGAWPFHRAAVANLRHGTAT-MDTLISLGVTAAYLWSLWALFFTAAG
MAB_4853c|M.abscessus_ATCC_199      ALAIGAYTFVPSTLRRLARGKIG-VGTLMTIAAIGAVILG----------
                                    .    .:.*  .:      .     ..*:: .. .:              

Mb3298|M.bovis_AF2122/97            ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
Rv3270|M.tuberculosis_H37Rv         ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
MMAR_1271|M.marinum_M               ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
MUL_2616|M.ulcerans_Agy99           ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
MAV_4235|M.avium_104                ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
MLBr_00747|M.leprae_Br4923          ---------------------ENVVALAVLWLLNIGEYLQDLTLRRTRRA
MSMEG_6058|M.smegmatis_MC2_155      ---------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRA
Mflv_0912|M.gilvum_PYR-GCK          TPGMKHPFELTLAPSHGAANIYLEVAAGVTTFILAGRYFEKRSKRQAGAA
Mvan_4449|M.vanbaalenii_PYR-1       IPGMTHPFELTIARTDGTSNIYLEAAAGVTTFILAGRYFEARAKRRAGAA
TH_4361|M.thermoresistible__bu      MPGMTMTFTLLPADT-GEPHIYLEVAAAVTTFIIAGRYFEARAKRQSGAA
MAB_4853c|M.abscessus_ATCC_199      ---------------------EVGEAAMLAFLFSISEGLEEYALARTRRG
                                                             *  :  ::  .. ::  :  ::  .

Mb3298|M.bovis_AF2122/97            ISELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAI
Rv3270|M.tuberculosis_H37Rv         ISELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAI
MMAR_1271|M.marinum_M               ISELLRGNQDTAWIRLTD---GPEAGTEVQVPIDSVQIGDEVVVHDHVAI
MUL_2616|M.ulcerans_Agy99           ISELLRGNQDTAWIRLTD---GPEAGTEVQVPIDSVQIGDEVVVHDHVAI
MAV_4235|M.avium_104                ISELLRGSQDTAWIRLEH--------NEIQVATDTLQIGDEVVVHDHVAI
MLBr_00747|M.leprae_Br4923          ISALLSGTQDTAWIRLTD---GPQAGTEIQVPIGTVQIGDEVVVHEHVAI
MSMEG_6058|M.smegmatis_MC2_155      IANLLQGTQDTVWLRLAD-------RTEIEVAVDGVRVGDQVVIHEQVAI
Mflv_0912|M.gilvum_PYR-GCK          LRALLNLGAKDVSVLRDG--------VETKIAIEELMVGDEFVVRPGEKI
Mvan_4449|M.vanbaalenii_PYR-1       LRALLELGAREVTVRRGG--------AEQRIPIEQLVIGDEFVVRPGEKI
TH_4361|M.thermoresistible__bu      LRALLDMGANDVAVLRDG--------AEKRVPIGELHVGDVFVVRPGEKI
MAB_4853c|M.abscessus_ATCC_199      LRALLSLAPEEATVLRDG--------TETTITATELQVGDTMLVRPGERV
                                    :  **      . :             *  :.   : :** .:::    :

Mb3298|M.bovis_AF2122/97            PVDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHA
Rv3270|M.tuberculosis_H37Rv         PVDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHA
MMAR_1271|M.marinum_M               PVDGEVVDGEAIVNQSAITGENLPVSVVAGATVHAGSVVVRGRLVVRAQA
MUL_2616|M.ulcerans_Agy99           PVDGEVVDGEAIVNQSAITGENLPVSVVAGATVHAGSVVVRGRLVVRAQA
MAV_4235|M.avium_104                PVDGEVIDGEAIVDQSAITGENLPVSVVVGMPVHAGSVVVRGRLVVRARA
MLBr_00747|M.leprae_Br4923          PVDGEVIDGEAVVNQSAITGENLPVSVMAGSHVHAGSVVVRGRLMVRASA
MSMEG_6058|M.smegmatis_MC2_155      VVDGVVCDGEAIVDQSAITGENLPVAVGPGSKVYAGSVVVRGRLVVTAEA
Mflv_0912|M.gilvum_PYR-GCK          ATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGRLVVRASR
Mvan_4449|M.vanbaalenii_PYR-1       AADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGRLVVRADR
TH_4361|M.thermoresistible__bu      ATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVRATR
MAB_4853c|M.abscessus_ATCC_199      ATDGTITAGRTALNTSAITGESVPVEAGPGDEVFAGSINGNGVLQVRVSA
                                     .** :  * : :: * :***.:*  .  *  * ..::   * : * .  

Mb3298|M.bovis_AF2122/97            VGNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLIT
Rv3270|M.tuberculosis_H37Rv         VGNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLIT
MMAR_1271|M.marinum_M               VGNQTTIGRIITRVEEAQNDRAPIQTVGENFSRRFVPTSFIVSAITLLVT
MUL_2616|M.ulcerans_Agy99           VGNQTTIGRIITRVEEAQNDRAPIQTVGENFSRRFVPTSFIVSAITLLVT
MAV_4235|M.avium_104                VGNQTTIGRIITRVEEAQHDRAPIQTVGENFSRRFVPTSFIVSAITLAVT
MLBr_00747|M.leprae_Br4923          VGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAITLAIT
MSMEG_6058|M.smegmatis_MC2_155      VGSHTTIGRIITRVEEAQQHRAPIQTVGENFSRRFVPASFLLSAATLVVT
Mflv_0912|M.gilvum_PYR-GCK          VGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVP--IVIAIAVITLG
Mvan_4449|M.vanbaalenii_PYR-1       VGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVP--IVIALSVATLG
TH_4361|M.thermoresistible__bu      VGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVP--IVIALSALTLA
MAB_4853c|M.abscessus_ATCC_199      TAADNSLARIVAIVEAEQSRKGASQRLADRIAKPLVPAIMITAAAIAVLG
                                    .. .. :.::   *   *  :.  * :.:..:  :**  :: :     : 

Mb3298|M.bovis_AF2122/97            GDVR-----------RAMTMLLIACPCAVGLSTPTAISAAIGNGARRGIL
Rv3270|M.tuberculosis_H37Rv         GDVR-----------RAMTMLLIACPCAVGLSTPTAISAAIGNGARRGIL
MMAR_1271|M.marinum_M               GDVR-----------RAMTMLLIACPCAVGLSTPTAISAAIGNGARRGIL
MUL_2616|M.ulcerans_Agy99           GDVR-----------RAMTMLLIACPCAVGLSTPTAISAAIGNGARRGIL
MAV_4235|M.avium_104                GDVR-----------RAMTMLLIACPCAVGLATPTAISAAIGNGARRGIL
MLBr_00747|M.leprae_Br4923          KDVR-----------RTMTVLLIACPCAVGLATPTAISAAIGNGARRGIL
MSMEG_6058|M.smegmatis_MC2_155      RDVR-----------RAMTMLLVACPCAVGLATPTVISAAIGNGARRGIL
Mflv_0912|M.gilvum_PYR-GCK          AWLG-AGFSVTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGAQMGVL
Mvan_4449|M.vanbaalenii_PYR-1       FWIG-SGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGIL
TH_4361|M.thermoresistible__bu      GWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGIL
MAB_4853c|M.abscessus_ATCC_199      SVFG----DPLVWIERALVVLVAASPCALAISVPVTVVAAIGAASKLGVL
                                      .             ::.:*: *.***:.::.*..: .. * .:: *:*

Mb3298|M.bovis_AF2122/97            IKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYA
Rv3270|M.tuberculosis_H37Rv         IKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYA
MMAR_1271|M.marinum_M               IKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIIAMHKDWEPEQVLAYA
MUL_2616|M.ulcerans_Agy99           IKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIIAMHKDWEPEQVLAYA
MAV_4235|M.avium_104                IKGGSHLEQAGQVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYA
MLBr_00747|M.leprae_Br4923          IKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSPEQVLAYA
MSMEG_6058|M.smegmatis_MC2_155      IKGGSHLEQAGRVDAMVFDKTGTLTLGRPIVTNVVAFHKDWEPEQVLAYA
Mflv_0912|M.gilvum_PYR-GCK          IKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGTE-RAELLRLA
Mvan_4449|M.vanbaalenii_PYR-1       IKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGEQ-PDEVLRVA
TH_4361|M.thermoresistible__bu      IKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGLS-ETELLRLA
MAB_4853c|M.abscessus_ATCC_199      VKGGAALEALGVVRTIALDKTGTLTANRPTVIEVAATAGAT-GERVLSAA
                                    :**   **    : :: :*****:* .   : .: .        .:*  *

Mb3298|M.bovis_AF2122/97            ASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLL
Rv3270|M.tuberculosis_H37Rv         ASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLL
MMAR_1271|M.marinum_M               ASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLL
MUL_2616|M.ulcerans_Agy99           ASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLL
MAV_4235|M.avium_104                ASSEIHSRHPLAEAVIRSTEERHITIPPHEECEVLVGLGMRTWADGRTLL
MLBr_00747|M.leprae_Br4923          ASSEIHSRHPLAEAVIRSTEERHISIPPHEECEVLVGLGMRTWADGRTLL
MSMEG_6058|M.smegmatis_MC2_155      ASSEIHARHPLAEAVIRSTRERHIVIPPHEECEVLVGLGMRTRADGRTLL
Mflv_0912|M.gilvum_PYR-GCK          GALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQGVVDGHAVV
Mvan_4449|M.vanbaalenii_PYR-1       GAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQVDGRAVL
TH_4361|M.thermoresistible__bu      GAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGHDVR
MAB_4853c|M.abscessus_ATCC_199      AALESRSEHPLAAAILAAAG----SVDPADDVEAVTSAGLTGRRGGHTLR
                                    .: *  :.**:* *:   :      :          . *:    .*: : 

Mb3298|M.bovis_AF2122/97            LGSPSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDE
Rv3270|M.tuberculosis_H37Rv         LGSPSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDE
MMAR_1271|M.marinum_M               LGSPSLLESEQVKVSKKASEWVGKLRQQAETPLLLAVDGTLVGLISLRDE
MUL_2616|M.ulcerans_Agy99           LGSPSLLESEQVKVSKKASEWVGKLRQQAETPLLLAVDGTLVGLISLRDE
MAV_4235|M.avium_104                LGSPSLLQAEKVKVSKKAKEWVDKLRRQAETPLLLAVDGTLVGLISLRDE
MLBr_00747|M.leprae_Br4923          LGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLISLRDE
MSMEG_6058|M.smegmatis_MC2_155      LGSPSLLRQEKVRVTSRAAAWVDKLRKRAETPLLLAVDGKLVGLISLRDE
Mflv_0912|M.gilvum_PYR-GCK          VGRESLLADWAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQARGVLVVADT
Mvan_4449|M.vanbaalenii_PYR-1       LGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARGVLMVADA
TH_4361|M.thermoresistible__bu      VGRLAWLGLSAGDR---LRNAAAQAEAAGHTPVWVAVDGRIAGVIVVSDT
MAB_4853c|M.abscessus_ATCC_199      LGRPGWIDPG------SLAPDVARMQQGGATAVLVEEDGQLLGAIAVRDE
                                    :*    :                  .    * : .  **   * : : * 

Mb3298|M.bovis_AF2122/97            VRPEAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPE
Rv3270|M.tuberculosis_H37Rv         VRPEAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPE
MMAR_1271|M.marinum_M               VRPEAAEVLTKLRDNGVRRIVMLTGDHPDIAKVVAEELGIDEWRAEVMPE
MUL_2616|M.ulcerans_Agy99           VRPEAAEVLTKLRDNGVRRIVMLTGDHPDIAKVVAEELGIDEWRAEVMPE
MAV_4235|M.avium_104                VRPEAAGVLKKLRANGIRRIVMLTGDHPDIAAVVADELGIDEWRAEVMPE
MLBr_00747|M.leprae_Br4923          VRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMPE
MSMEG_6058|M.smegmatis_MC2_155      VRPEAAEVLRALRTAGVRRMVMLTGDHPDAAAAVADELGITEWRAEVLPE
Mflv_0912|M.gilvum_PYR-GCK          VKPTSAQAISQMRDLGLT-PVLLTGDNEAVARQIAAEVGIDTVIAEVMPK
Mvan_4449|M.vanbaalenii_PYR-1       VKPTSAEAISLLKRLGLT-PIMVTGDNEAVARAVAAEVGIDEVIAGVLPQ
TH_4361|M.thermoresistible__bu      VKDHAAEAIAELRALGAT-PVLLTGDNDRAARTVAAQVGIDDVIAGVLPA
MAB_4853c|M.abscessus_ATCC_199      LRPEAAHVIAALHRSGYR-VAMLTGDNAATATTLARQVGIDTVHADLRPE
                                    ::  :* .:  ::  *     ::***:   *  :* ::**    * : * 

Mb3298|M.bovis_AF2122/97            DKLAAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETA
Rv3270|M.tuberculosis_H37Rv         DKLAAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETA
MMAR_1271|M.marinum_M               DKLEVVRDLQDEGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETA
MUL_2616|M.ulcerans_Agy99           DKLEVVRDLQDEGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETA
MAV_4235|M.avium_104                DKLAAVRDLQEEGFVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETA
MLBr_00747|M.leprae_Br4923          DKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVETA
MSMEG_6058|M.smegmatis_MC2_155      DKLAVVRRLHAEGHTVAVIGDGVNDAPALAAADIGIAMGLGGTDVAVETA
Mflv_0912|M.gilvum_PYR-GCK          DKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTG-TDVAIEAS
Mvan_4449|M.vanbaalenii_PYR-1       DKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSG-TDVAIEAS
TH_4361|M.thermoresistible__bu      EKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG-TDVAIEAS
MAB_4853c|M.abscessus_ATCC_199      DKARIITELR-QQHPTAMVGDGVNDAPALATADLGIAMGAMGTDVAIETA
                                    :*   :  *:     ..::***:***.*** **:*:*:*   ****:*::

Mb3298|M.bovis_AF2122/97            DVALANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALS
Rv3270|M.tuberculosis_H37Rv         DVALANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALS
MMAR_1271|M.marinum_M               DVALANDDLHRLLDVRDLGGRAVDVIRQNYGMSIAVNAAGLLIGAGGALS
MUL_2616|M.ulcerans_Agy99           DVALANDDLHRLLDIRDLGGRAVDVIRQNYGMSIAVNAAGLLIGAGGALS
MAV_4235|M.avium_104                DVALSNDDLHRLLDVRDLGSRAVDVIRENYGMSIAVNAAGLIIGAGGALS
MLBr_00747|M.leprae_Br4923          DVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGALS
MSMEG_6058|M.smegmatis_MC2_155      DVALASDDLRRLLDVRDLGARAVDVIQQNYAMSIAVNAIGLAVGAGGALS
Mflv_0912|M.gilvum_PYR-GCK          DITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAIPVAALGMLN
Mvan_4449|M.vanbaalenii_PYR-1       DLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPLAAAGLLN
TH_4361|M.thermoresistible__bu      DLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAAGLLN
MAB_4853c|M.abscessus_ATCC_199      DVALMGEDLRHLTQALAHARRARTIMLQNVGLSLALIAVLIPLALLGILG
                                    *::*   **.   :    .  :   :  *   ::*  .  : :.  * *.

Mb3298|M.bovis_AF2122/97            PVLAAILHNASSVAVVANSSRLIRYRLDR----------------
Rv3270|M.tuberculosis_H37Rv         PVLAAILHNASSVAVVANSSRLIRYRLDR----------------
MMAR_1271|M.marinum_M               PVLAAILHNASSVAVVANSSRLIRYRLE-----------------
MUL_2616|M.ulcerans_Agy99           PVLAAILHNASSVVVVANSSRLIRYRLE-----------------
MAV_4235|M.avium_104                PVLAAILHNASSVAVVANSSRLIRYRLN-----------------
MLBr_00747|M.leprae_Br4923          PVLAAVLHNASSVAVVANSSRLIRYRLD-----------------
MSMEG_6058|M.smegmatis_MC2_155      PVLAAVLHNASSVAVVANSARLIRYEID-----------------
Mflv_0912|M.gilvum_PYR-GCK          PMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH-----------
Mvan_4449|M.vanbaalenii_PYR-1       PMIAGAAMAFSSVFVVSNSLRLRAFTPSR----------------
TH_4361|M.thermoresistible__bu      PLIAGAAMAFSSVFVVSNSLRLRRFTPSR----------------
MAB_4853c|M.abscessus_ATCC_199      LAAVVAVHELAEIVVIANGVRAGRTQPLTAPEHANTPAAQLAQQE
                                       .      :.: *:.*. *