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M. avium 104 MAV_5246 (-)

annotation: copper-translocating P-type ATPase
coordinates: 5396520 - 5398808
length: 762

MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYATEKAAVSAPASYDP
QTLITEIENAGYAAAVATPSPPRDDPELASLRRRLVTAIALAGPVIAVAMIPALQFQHWHWAALALTAPV
VGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVA
APCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLRAGAETRIPIERLAVGDEFVV
RPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLV
ERAQSGKADAQRLADRVSGVFVPVVLLLAVATLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTAL
LVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGTDRATLLRYAGALEAASE
HPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHD
GKTVVAVGWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIGEVISGALP
ADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSR
RTLATIKTNLVWAFGYNLAAIPLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5246--100% (762)copper-translocating P-type ATPase
M. avium 104MAV_4235cadA2e-8832.97% (731) cadmium-translocating P-type ATPase
M. avium 104MAV_1172kdpB3e-4831.40% (516) potassium-transporting ATPase subunit B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA0.049.73% (752) cation transporter P-type ATPase A
M. gilvum PYR-GCKMflv_0912-0.069.85% (753) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0092ctpA0.049.73% (752) cation transporter P-type ATPase A
M. leprae Br4923MLBr_02000ctpB1e-17547.72% (746) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-0.055.25% (753) putative metal transporter ATPase
M. marinum MMMAR_0231ctpA_10.072.72% (755) cation transporter p-type ATPase CtpA_1
M. smegmatis MC2 155MSMEG_5014-0.066.27% (747) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.061.48% (758) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4850ctpA0.050.00% (748) cation transporter p-type ATPase a CtpA
M. vanbaalenii PYR-1Mvan_4449-0.065.67% (737) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MMAR_0231|M.marinum_M               -------MPETTG--LPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVS
Mflv_0912|M.gilvum_PYR-GCK          ------MALMTTSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
Mvan_4449|M.vanbaalenii_PYR-1       -------------------MNTIELSIGGMTCASCAARVEKKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MLBr_02000|M.leprae_Br4923          ---MTASLVEDTNNN-HESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
                                                            * : ** * :** :::  **:: ** 

MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATP------SPPRD
MMAR_0231|M.marinum_M               ATVNYATERATVTAPAGYDPQILITEVKKAGYAAALPQHRQQPAAAAKTD
Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
Mvan_4449|M.vanbaalenii_PYR-1       ATVNFATEKARVAFGDEVSPGQLVSAVESAGYQAELPERPD-----EPAE
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDSDAE
MLBr_02000|M.leprae_Br4923          ASVNFATRVATIDA-VDVAVDELRQVIEQAGYRATAHAESAVEEIDPDAD
                                    * ** . . * :          *   :. .** *                

MAV_5246|M.avium_104                ----------DPELASLRRRLVTAIALAGPVIAVAMIPALQFQHWHWAAL
MMAR_0231|M.marinum_M               TH------GVDPELASLRGRLVGAVVLAGPVILMAMLPALQFRYWQWASL
Mflv_0912|M.gilvum_PYR-GCK          TPN-AD-GIDDPELASLRHRLRASTVLTVPVIAMAMIPALQFTYWQWASL
MSMEG_5014|M.smegmatis_MC2_155      PE--------DRATDALRTRLLVSAVLTVPVIAMAMVPALQFTNWQWLSL
Mvan_4449|M.vanbaalenii_PYR-1       PT--------DDPTAALKRRLLICVALSVPVIAMAMVPVLQFTYWQWLSL
TH_4361|M.thermoresistible__bu      ATG-AAGDDHDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLAL
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVISMAMPLHFSGWEILVA
Mb0095|M.bovis_AF2122/97            HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
Rv0092|M.tuberculosis_H37Rv         HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
MUL_4850|M.ulcerans_Agy99           HAR--------HLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT
MLBr_02000|M.leprae_Br4923          YAR--------NLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWGYLLT
                                                              ::     ..:    :*  *     

MAV_5246|M.avium_104                ALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVL
MMAR_0231|M.marinum_M               ALAAPVIVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLYALFL
Mflv_0912|M.gilvum_PYR-GCK          TLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLYALFF
MSMEG_5014|M.smegmatis_MC2_155      TLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYALFW
Mvan_4449|M.vanbaalenii_PYR-1       TLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAALGWSIYALFW
TH_4361|M.thermoresistible__bu      TLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLWALFF
MAB_3984c|M.abscessus_ATCC_199      ALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLWVLFA
Mb0095|M.bovis_AF2122/97            ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
Rv0092|M.tuberculosis_H37Rv         ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
MUL_4850|M.ulcerans_Agy99           ALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLYTVFG
MLBr_02000|M.leprae_Br4923          ALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFV
                                    :*: *:: * . ***  *  * ::  ::*:**:* *  :*  **: .:. 

MAV_5246|M.avium_104                GAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFE
MMAR_0231|M.marinum_M               GTAGEPGMRHPFELTITPGDGAS------NIYLEVAAGVIAFVLAGRYFE
Mflv_0912|M.gilvum_PYR-GCK          GTAGTPGMKHPFELTLAPSHGAA------NIYLEVAAGVTTFILAGRYFE
MSMEG_5014|M.smegmatis_MC2_155      GTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAGRYFE
Mvan_4449|M.vanbaalenii_PYR-1       GTAGIPGMTHPFELTIARTDGTS------NIYLEAAAGVTTFILAGRYFE
TH_4361|M.thermoresistible__bu      TAAGMPGMTMTFTLLPADT-GEP------HIYLEVAAAVTTFIIAGRYFE
MAB_3984c|M.abscessus_ATCC_199      NAGHTHGDVH--------------------VYFEVVAAVTVFLLAGRFAE
Mb0095|M.bovis_AF2122/97            NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE
Rv0092|M.tuberculosis_H37Rv         NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE
MUL_4850|M.ulcerans_Agy99           SHQLADRKGIWQALLGSDA-----------IYFEVAAGVTVFVLAGRYFE
MLBr_02000|M.leprae_Br4923          DKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAGRFFE
                                                                  :*:*..*.*  *::.**: *

MAV_5246|M.avium_104                RRSKRTAGAALRALLALGAKDVAVL-RAGAETRIPIERLAVGDEFVVRPG
MMAR_0231|M.marinum_M               KRSKRRAGAALQALLELGAKDVAVL-RNGAEIRVPVQELTVDDEFVVRPG
Mflv_0912|M.gilvum_PYR-GCK          KRSKRQAGAALRALLNLGAKDVSVL-RDGVETKIAIEELMVGDEFVVRPG
MSMEG_5014|M.smegmatis_MC2_155      AKSKRRASAALRALMELGAKDVAIL-RNGAEQRIPIDQLGVGDEFVVRPG
Mvan_4449|M.vanbaalenii_PYR-1       ARAKRRAGAALRALLELGAREVTVR-RGGAEQRIPIEQLVIGDEFVVRPG
TH_4361|M.thermoresistible__bu      ARAKRQSGAALRALLDMGANDVAVL-RDGAEKRVPIGELHVGDVFVVRPG
MAB_3984c|M.abscessus_ATCC_199      SRAKRSAGSALRALLSLGAKDVAVL-RGGHETRIPVDQLAVGDEFVVRPG
Mb0095|M.bovis_AF2122/97            ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
Rv0092|M.tuberculosis_H37Rv         ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
MUL_4850|M.ulcerans_Agy99           ARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPG
MLBr_02000|M.leprae_Br4923          ARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPG
                                     ::*  :.:**:**   .*.:* :    * *  :.  .*   : *:****

MAV_5246|M.avium_104                ERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVR
MMAR_0231|M.marinum_M               EKIATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGRLVVR
Mflv_0912|M.gilvum_PYR-GCK          EKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGRLVVR
MSMEG_5014|M.smegmatis_MC2_155      EKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRLVVR
Mvan_4449|M.vanbaalenii_PYR-1       EKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGRLVVR
TH_4361|M.thermoresistible__bu      EKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVR
MAB_3984c|M.abscessus_ATCC_199      ERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGRIVVR
Mb0095|M.bovis_AF2122/97            QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
Rv0092|M.tuberculosis_H37Rv         QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
MUL_4850|M.ulcerans_Agy99           QTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVE
MLBr_02000|M.leprae_Br4923          ETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIE
                                    : :::** .  * :::* : :***: * ..  .. * *. .   *:: :.

MAV_5246|M.avium_104                ATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATL
MMAR_0231|M.marinum_M               ATRVGEHTQLAQMAKLVEAAQSGKADVQRLADRVSGVFVPIVIAIAVTTL
Mflv_0912|M.gilvum_PYR-GCK          ASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIAVITL
MSMEG_5014|M.smegmatis_MC2_155      ANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAVATL
Mvan_4449|M.vanbaalenii_PYR-1       ADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPIVIALSVATL
TH_4361|M.thermoresistible__bu      ATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSALTL
MAB_3984c|M.abscessus_ATCC_199      ANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAISALTF
Mb0095|M.bovis_AF2122/97            AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
Rv0092|M.tuberculosis_H37Rv         AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
MUL_4850|M.ulcerans_Agy99           AAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIAALTA
MLBr_02000|M.leprae_Br4923          ATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIAGLAG
                                    *  :* .*::* *..:*  **  ** .*:****::.**** *: ::  : 

MAV_5246|M.avium_104                AGWLA-AGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLGV
MMAR_0231|M.marinum_M               GVWLG-AGYPVSAALTAAVAVLIIACPCALGLATPTALLVGTGRAAALGV
Mflv_0912|M.gilvum_PYR-GCK          GAWLG-AGFSVTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGAQMGV
MSMEG_5014|M.smegmatis_MC2_155      GFWLG-TGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
Mvan_4449|M.vanbaalenii_PYR-1       GFWIG-SGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGI
TH_4361|M.thermoresistible__bu      AGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
MAB_3984c|M.abscessus_ATCC_199      VAWAA-LGNSLASAFTAAVAVLIIACPCALGLATPTAILVGTGRGAQLGV
Mb0095|M.bovis_AF2122/97            AGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
Rv0092|M.tuberculosis_H37Rv         AGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
MUL_4850|M.ulcerans_Agy99           AGWLL-AGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI
MLBr_02000|M.leprae_Br4923          ASWLL-AGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGAQLGI
                                      *    .     *.:..:.**:*****:********::*.:**.* :*:

MAV_5246|M.avium_104                LIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DRATLL
MMAR_0231|M.marinum_M               LIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDT---DRATAL
Mflv_0912|M.gilvum_PYR-GCK          LIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT---ERAELL
MSMEG_5014|M.smegmatis_MC2_155      LIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DRDDVL
Mvan_4449|M.vanbaalenii_PYR-1       LIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE---QPDEVL
TH_4361|M.thermoresistible__bu      LIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SETELL
MAB_3984c|M.abscessus_ATCC_199      LIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADADEIL
Mb0095|M.bovis_AF2122/97            FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
Rv0092|M.tuberculosis_H37Rv         FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
MUL_4850|M.ulcerans_Agy99           FLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DADEVL
MLBr_02000|M.leprae_Br4923          FIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGW---CSGEVL
                                    ::** . **  . :**:::*****:* * : :  *    .         *

MAV_5246|M.avium_104                RYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGH
MMAR_0231|M.marinum_M               RYAGGLEAASEHPIAAAIVKSARAELGALPEPADFANTEGQGVRGIIDGH
Mflv_0912|M.gilvum_PYR-GCK          RLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQGVVDGH
MSMEG_5014|M.smegmatis_MC2_155      RVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTVEGR
Mvan_4449|M.vanbaalenii_PYR-1       RVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQVDGR
TH_4361|M.thermoresistible__bu      RLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGH
MAB_3984c|M.abscessus_ATCC_199      RIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGVVDGQ
Mb0095|M.bovis_AF2122/97            ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
Rv0092|M.tuberculosis_H37Rv         ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
MUL_4850|M.ulcerans_Agy99           AIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGTVSGR
MLBr_02000|M.leprae_Br4923          ALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSGVVAEH
                                      *. :* :***.:* *:.               *    * ** * :  :

MAV_5246|M.avium_104                AVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILAL
MMAR_0231|M.marinum_M               AVIVGRASLLADWAQHLDPDLAAAKDRAESQGKTAVAVGWDGRARAILVI
Mflv_0912|M.gilvum_PYR-GCK          AVVVGRESLLADWAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQARGVLVV
MSMEG_5014|M.smegmatis_MC2_155      AVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGVLVV
Mvan_4449|M.vanbaalenii_PYR-1       AVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARGVLMV
TH_4361|M.thermoresistible__bu      DVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAGVIVV
MAB_3984c|M.abscessus_ATCC_199      EVSI----------------------EAIEGQNTTAAVSWGGLRRGEIEV
Mb0095|M.bovis_AF2122/97            AVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAV
Rv0092|M.tuberculosis_H37Rv         AVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAV
MUL_4850|M.ulcerans_Agy99           SVRVGKPSWIG--SSSSDTALRAALRNAESLGETAVFVEIDGGPCGVIAV
MLBr_02000|M.leprae_Br4923          HVKIGKPSWVTR-NAPCDVVLESARREGESRGETVVFVSVDGVACGAVAI
                                     * :                       .    .* . *  .*   . : :

MAV_5246|M.avium_104                ADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--EVISG
MMAR_0231|M.marinum_M               ADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGID--EVIAD
Mflv_0912|M.gilvum_PYR-GCK          ADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID--TVIAE
MSMEG_5014|M.smegmatis_MC2_155      ADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--DVYAE
Mvan_4449|M.vanbaalenii_PYR-1       ADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGID--EVIAG
TH_4361|M.thermoresistible__bu      SDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--DVIAG
MAB_3984c|M.abscessus_ATCC_199      ADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGDVIAG
Mb0095|M.bovis_AF2122/97            ADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIAD
Rv0092|M.tuberculosis_H37Rv         ADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIAD
MUL_4850|M.ulcerans_Agy99           ADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--EVIAN
MLBr_02000|M.leprae_Br4923          ADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID--TVIAD
                                    :*:**  :  *:  :   *  .:::****   *   * .:**    * : 

MAV_5246|M.avium_104                ALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVAI
MMAR_0231|M.marinum_M               VLPAGKVAAVRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGADVAI
Mflv_0912|M.gilvum_PYR-GCK          VMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTGTDVAI
MSMEG_5014|M.smegmatis_MC2_155      VLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDVAI
Mvan_4449|M.vanbaalenii_PYR-1       VLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSGTDVAI
TH_4361|M.thermoresistible__bu      VLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGTDVAI
MAB_3984c|M.abscessus_ATCC_199      VKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGTDAAI
Mb0095|M.bovis_AF2122/97            ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAI
Rv0092|M.tuberculosis_H37Rv         ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAI
MUL_4850|M.ulcerans_Agy99           ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVAI
MLBr_02000|M.leprae_Br4923          MLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGTDVAI
                                      *  *.  : :*:  *: ***:***:**..*** **:*:::* *:*.**

MAV_5246|M.avium_104                EAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAALG
MMAR_0231|M.marinum_M               EAADLTLVRGDLRAAADAIRLSRRTLNTIKTNLFWAFGYNVAALPLAAFG
Mflv_0912|M.gilvum_PYR-GCK          EASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAIPVAALG
MSMEG_5014|M.smegmatis_MC2_155      EAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLAAAG
Mvan_4449|M.vanbaalenii_PYR-1       EASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPLAAAG
TH_4361|M.thermoresistible__bu      EASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAAG
MAB_3984c|M.abscessus_ATCC_199      EASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPLAALG
Mb0095|M.bovis_AF2122/97            GAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAG
Rv0092|M.tuberculosis_H37Rv         GAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAG
MUL_4850|M.ulcerans_Agy99           GAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPIAAAG
MLBr_02000|M.leprae_Br4923          GAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASSG
                                     *.*: :* . *  .  *: *.  *: *:: *: ***.** **:*:*: *

MAV_5246|M.avium_104                MLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA---------------
MMAR_0231|M.marinum_M               LLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWDATPE
Mflv_0912|M.gilvum_PYR-GCK          MLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH-------------
MSMEG_5014|M.smegmatis_MC2_155      LLNPMLAGAAMAFSSVFVVSNSLRLKRFR---------------------
Mvan_4449|M.vanbaalenii_PYR-1       LLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR------------------
TH_4361|M.thermoresistible__bu      LLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR------------------
MAB_3984c|M.abscessus_ATCC_199      LLNPMIAGAAMAMSSVFVVLNSLRLRTFR---------------------
Mb0095|M.bovis_AF2122/97            LLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA-
Rv0092|M.tuberculosis_H37Rv         LLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA-
MUL_4850|M.ulcerans_Agy99           VLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQTTTSTTEPGATE
MLBr_02000|M.leprae_Br4923          LLNPLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQTSD--
                                    :***::******:**.:** ***:*  *                      

MAV_5246|M.avium_104                -----------------
MMAR_0231|M.marinum_M               SPAELSTLPGEPSGCPR
Mflv_0912|M.gilvum_PYR-GCK          -----------------
MSMEG_5014|M.smegmatis_MC2_155      -----------------
Mvan_4449|M.vanbaalenii_PYR-1       -----------------
TH_4361|M.thermoresistible__bu      -----------------
MAB_3984c|M.abscessus_ATCC_199      -----------------
Mb0095|M.bovis_AF2122/97            -----------------
Rv0092|M.tuberculosis_H37Rv         -----------------
MUL_4850|M.ulcerans_Agy99           -----------------
MLBr_02000|M.leprae_Br4923          -----------------