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M. thermoresistible (build 8) TH_2531 (-)

annotation: copper-translocating P-type ATPase
coordinates: 4123057 - 4125141
length: 695

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2531--100% (695)copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-e-10837.96% (677) PUTATIVE heavy metal translocating P-type ATPase
M. thermoresistible (build 8)TH_0097-2e-3326.97% (456) P-type ATPase - metal cation transport

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0994ctpV1e-11540.03% (647) metal cation transporter P-type ATPase CtpV
M. gilvum PYR-GCKMflv_0915-0.070.72% (690) copper-translocating P-type ATPase
M. tuberculosis H37RvRv0969ctpV1e-11540.03% (647) metal cation transporter P-type ATPase CtpV
M. leprae Br4923MLBr_01987ctpA1e-10538.32% (655) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_0449-0.072.32% (643) copper-transporting ATPase
M. marinum MMMAR_4876ctpV1e-12241.95% (646) metal cation transporter p-type ATPase, CtpV
M. avium 104MAV_5246-1e-10138.78% (673) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-1e-10437.52% (661) copper-translocating P-type ATPase
M. ulcerans Agy99MUL_0423ctpV1e-12142.26% (646) metal cation transporter p-type ATPase, CtpV
M. vanbaalenii PYR-1Mvan_3678-1e-13843.29% (700) copper-translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_5246|M.avium_104                --------------------------------------MSTPPRHIDEGT
MSMEG_5014|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01987|M.leprae_Br4923          --------------------------------------------------
Mb0994|M.bovis_AF2122/97            ------------------------------------MRVCVTGFNVDAVR
Rv0969|M.tuberculosis_H37Rv         ------------------------------------MRVCVTGFNVDAVR
MMAR_4876|M.marinum_M               -------------MLATELACAADATVTVVSAAAGRMRVHANGLAIDATR
MUL_0423|M.ulcerans_Agy99           ------------------------------------MRVHANGFAIDATR
Mflv_0915|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0449|M.abscessus_ATCC_1997      --------------------------------------------------
TH_2531|M.thermoresistible__bu      --------------------------------------------------
Mvan_3678|M.vanbaalenii_PYR-1       MTKSTILDVHGLNWASSTAVVEATLLRRPGVTSVEANAVNQTATVVYDPT
                                                                                      

MAV_5246|M.avium_104                FPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYATEKAAV
MSMEG_5014|M.smegmatis_MC2_155      ---MTTATGHVELQIGGMTCASCAARIERKLNKLDGVTASVNYATEKASV
MLBr_01987|M.leprae_Br4923          ---MRAPNGWNNLP-----------------NKLSDFSTLVNSATRVAAI
Mb0994|M.bovis_AF2122/97            AVAIEETVSQVTGVHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHV
Rv0969|M.tuberculosis_H37Rv         AVAIEETVSQVTGVHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHV
MMAR_4876|M.marinum_M               AAAIEESVGRVGGVRAVRAYPRTASVVIWYSPAQCDTAAIVSAIAEAEHA
MUL_0423|M.ulcerans_Agy99           AAAIEESVGRVGGVRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHA
Mflv_0915|M.gilvum_PYR-GCK          ------------------------------MTNHDQHAEATPHTNHANHA
MAB_0449|M.abscessus_ATCC_1997      --------------------------------------------------
TH_2531|M.thermoresistible__bu      ------------------------------------------MVGPAHHG
Mvan_3678|M.vanbaalenii_PYR-1       TTSVADLAGWIRDCGFHCAGRSVPDHVCDPMSEPHHHPSATLDEQPTSAP
                                                                                      

MAV_5246|M.avium_104                SAPASYDPQTLITEIENAGYAAAVATPSP---------------------
MSMEG_5014|M.smegmatis_MC2_155      EVAGEVSPETLIEVVETAGYTAHLPAPPQ---------------------
MLBr_01987|M.leprae_Br4923          NLSEVTQTAEVCEAVRRAALCTDGGEALQ---------------------
Mb0994|M.bovis_AF2122/97            PAELVPARAPHSAGVRGVGVVRKITGGIRRMLS----------RPPGVDK
Rv0969|M.tuberculosis_H37Rv         PAELVPARAPHSAGVRGVGVVRKITGGIRRMLS----------RPPGVDK
MMAR_4876|M.marinum_M               GDASVPAPAARAAGIADSGIVGRVIGGLARALLGMRTADNDDDPPPEIAR
MUL_0423|M.ulcerans_Agy99           GDASAPAPAARVAGIADGGVVGRVIGGLARALLGMRTDDNDDDPPPEIAR
Mflv_0915|M.gilvum_PYR-GCK          THGEHGGHPDHQTNAAHDGHSGHAGHGAD---------------------
MAB_0449|M.abscessus_ATCC_1997      --------------------------------------------------
TH_2531|M.thermoresistible__bu      TVAADG-RAQHLTGRDHHRHG--HGDHAG---------------------
Mvan_3678|M.vanbaalenii_PYR-1       SPTAGEVHAHEAAPARTPQEAMGHGGGHAG--------------------
                                                                                      

MAV_5246|M.avium_104                -----------PRD-----DPE---LASLRRRLVTAIALAGP----VIAV
MSMEG_5014|M.smegmatis_MC2_155      -----------PETGGTEQDPEDRATDALRTRLLVSAVLTVP----VIAM
MLBr_01987|M.leprae_Br4923          -----------RRQ----ADADN--ARYLLIRLAVAAALFVPLAHLSVMF
Mb0994|M.bovis_AF2122/97            PLKASRCGGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGS
Rv0969|M.tuberculosis_H37Rv         PLKASRCGGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGS
MMAR_4876|M.marinum_M               LRAALDRIGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGL
MUL_0423|M.ulcerans_Agy99           LRAALDRIGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGL
Mflv_0915|M.gilvum_PYR-GCK          ------------------------HVAQFRKLFWINLIIAVPVIAFSTMF
MAB_0449|M.abscessus_ATCC_1997      -----------------------------------MLVVAVPVVVFDPMF
TH_2531|M.thermoresistible__bu      ------------------------HVAEFRRLFWVMLLLAVPTVAFSGMF
Mvan_3678|M.vanbaalenii_PYR-1       -------------------MSMDHMVRDMRNRFLVALALSIPIMLWSPMG
                                                                          :  *        

MAV_5246|M.avium_104                AMIPALQFQHW-----HWAALALTAPVVGWCGRPFHAAAWANLKHGVTTM
MSMEG_5014|M.smegmatis_MC2_155      AMVPALQFTNW-----QWLSLTLAAPVVVWGALPFHRAAWLNLRHGTATM
MLBr_01987|M.leprae_Br4923          AVLPSTHFPGW-----EWMLTALAIPVVTWAAWPFHRVAIHNARYHGASM
Mb0994|M.bovis_AF2122/97            SMFFG-AYPWA-----GWLAFAATLPVQFVAGWPILRGAVQQARALTSNM
Rv0969|M.tuberculosis_H37Rv         SMFFG-AYPWA-----GWLAFAATLPVQFVAGWPILRGAVQQARALTSNM
MMAR_4876|M.marinum_M               TMFFG-AYAWA-----GWLAFAATIPVQFIAGWPFLVGAVQQARARSANM
MUL_0423|M.ulcerans_Agy99           TMFFG-AYPWA-----GWLAFAATIPVQFIAGWPFLVGAVQQARARSANM
Mflv_0915|M.gilvum_PYR-GCK          AMLLGYAVPDFPGAR--WIAPLLGTVMYVVGGRPFLTGAVSEIRSRKPGM
MAB_0449|M.abscessus_ATCC_1997      AMLLGYQLPDAGWAR--WVFPVLGTVVYLWGGKPFLVGAVSEIRSRTPGM
TH_2531|M.thermoresistible__bu      AMILGYQVPRVPGAQ--WVSPVLGTVMYVWGGRPFLTGAISEIRSRTPGM
Mvan_3678|M.vanbaalenii_PYR-1       RDMFGFTVPAPFGLRDDVFTLLLSLPVVFYSAWIFFDGAWRALRARTLDM
                                      . .                     :    .  :   *    :     *

MAV_5246|M.avium_104                DTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPC
MSMEG_5014|M.smegmatis_MC2_155      DTLISMGTLAAFGWSLYALFWGTAGVPGMTHPFSLVG------SRTDGAG
MLBr_01987|M.leprae_Br4923          ETLISTGITAATIWSLYTVFGHHQSTEHRGVWRALLG-----------SD
Mb0994|M.bovis_AF2122/97            DTLIALGTLTAFVYSTYQLFAGGP--------------------------
Rv0969|M.tuberculosis_H37Rv         DTLIALGTLTAFVYSTYQLFAGGP--------------------------
MMAR_4876|M.marinum_M               NTLISLGTLTAFIYSTYQLFAGGP--------------------------
MUL_0423|M.ulcerans_Agy99           NTLISLGTLTAFIYSTYQLFAGGP--------------------------
Mflv_0915|M.gilvum_PYR-GCK          MLLIGLAITVAFLASWGASLGLLHHEL-----------------------
MAB_0449|M.abscessus_ATCC_1997      MLLIGLAITVAFTASWGASIGVLDHQL-----------------------
TH_2531|M.thermoresistible__bu      MLLIGLALTVAFLSSWGASLGVLDHRL-----------------------
Mvan_3678|M.vanbaalenii_PYR-1       MVLVAVAVGAGWLYSLGVTL--TGGGE-----------------------
                                      *:. .  ..   *    .                              

MAV_5246|M.avium_104                HVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR---
MSMEG_5014|M.smegmatis_MC2_155      NIYLEVAAGVTTFILAGRYFEAKSKRRASAALRALMELGAKDVAILR---
MLBr_01987|M.leprae_Br4923          AIYFEVAAGITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVLQP--
Mb0994|M.bovis_AF2122/97            -LFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV---
Rv0969|M.tuberculosis_H37Rv         -LFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV---
MMAR_4876|M.marinum_M               -LFFDTAALIIAFVVLGRYFEATAHGKTREAISKLLEMGAKEARLIV---
MUL_0423|M.ulcerans_Agy99           -LFFDTAALIIAFVVLGRYFEATAHGKTREAISKLLDMGAKETRLIV---
Mflv_0915|M.gilvum_PYR-GCK          -EFWWELALLIVIMLLGHWVEMRSLAQTTSALDSLAALLPDEAEKVD---
MAB_0449|M.abscessus_ATCC_1997      -SFWWELALLVVIMLAGHWIEMRSLAQTTSALDSLAALLPDTAERVQ---
TH_2531|M.thermoresistible__bu      -EFWWELALLIVIMLLGHWIELRSLARTTSALDSLAALLPDTAERVEQGP
Mvan_3678|M.vanbaalenii_PYR-1       -VFYEAASVLTAFVLLGHWFEMRARGGANDAIRTLLELAPPVAVVLR---
                                      :    : :  ::: *:     :   :  *:  *  : .  .  :    

MAV_5246|M.avium_104                -AGAETRIPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESV
MSMEG_5014|M.smegmatis_MC2_155      -NGAEQRIPIDQLGVGDEFVVRPGEKIATDGVVVDGSSAVDASMLTGESV
MLBr_01987|M.leprae_Br4923          -DGSEMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAK
Mb0994|M.bovis_AF2122/97            -DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESV
Rv0969|M.tuberculosis_H37Rv         -DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESV
MMAR_4876|M.marinum_M               -DGEEHLVPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESV
MUL_0423|M.ulcerans_Agy99           -DGEEHLVPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESV
Mflv_0915|M.gilvum_PYR-GCK          -GDRIITVSPADLQVGDLVVVRPGGSVPADGRIVDGRADMDESMVTGESR
MAB_0449|M.abscessus_ATCC_1997      -GQQVVTVPLADLRVGDIVVVRPGGSVPADGRVVEGSASLDESMVTGESA
TH_2531|M.thermoresistible__bu      DGETVTVVAPADLRVGDTVIVRPGAGIPADGRIIDGVADVDESMVTGESV
Mvan_3678|M.vanbaalenii_PYR-1       -DGEPVETPTAEVAVGDLLLIRPGAKIPVDGTVAEGTSDVDESMVTGESL
                                            .   :   : . :***  :..** :  * : :. : :***: 

MAV_5246|M.avium_104                PVEVGVGDGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKAD
MSMEG_5014|M.smegmatis_MC2_155      PVEVGPGDQVVGATVNVGGRLVVRANRIGSDTQLAQMARLVEDAQSGKAQ
MLBr_01987|M.leprae_Br4923          PVRVNPGAQVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVEQAQQQNAN
Mb0994|M.bovis_AF2122/97            PVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAP
Rv0969|M.tuberculosis_H37Rv         PVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAP
MMAR_4876|M.marinum_M               PVEKGVGDRVAGATVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAP
MUL_0423|M.ulcerans_Agy99           PVEKGVGDWVAGATVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAP
Mflv_0915|M.gilvum_PYR-GCK          PVARGVGEAVTAGTVATDSGLRVEITATGDDTALAGIQRLVIEAQNSSSR
MAB_0449|M.abscessus_ATCC_1997      PVRRGVGEQVVAGTVATDSGLRVQVSAVGADTALAGIQRLVADAQASTSR
TH_2531|M.thermoresistible__bu      PVRRGVGDRVVAATVATDSGLRITVTAVGDDTALAGIRRMVAEAQSSSSR
Mvan_3678|M.vanbaalenii_PYR-1       PVSKAPDSKVIGASINTTGTLRVLATKVGSDTVLAQIVAMVQEAQNSKAP
                                    **    .  * ..::   . * :     * :* ** :  :*  **  .: 

MAV_5246|M.avium_104                AQRLADRVSGVFVPVVLLLAVATLAGWLAAGGTLATALTAAVAVLIIACP
MSMEG_5014|M.smegmatis_MC2_155      AQRLADRVSAVFVPIVIALAVATLGFWLGTGGSVAAAFTAAVAVLIIACP
MLBr_01987|M.leprae_Br4923          AQRLADRIASVFVPCVFAVAALTAVGWLIAGSGPDRVFSAAIAVLVIACP
Mb0994|M.bovis_AF2122/97            VQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAGMTAAVAVLIIACP
Rv0969|M.tuberculosis_H37Rv         VQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAGMTAAVAVLIIACP
MMAR_4876|M.marinum_M               VQRLADRVSAVFVPVVVGIAAATFAGWTLLAANPVAGMTAAVSVLIIACP
MUL_0423|M.ulcerans_Agy99           VQRLADRVSAVFVPVVVRIAAATFAGWTLLAANPVAGMTAAVSVLIIACP
Mflv_0915|M.gilvum_PYR-GCK          AQRLADRAAGWLFWFALGTAAITAAAWSIVGD-PDASVVRAITVLVIACP
MAB_0449|M.abscessus_ATCC_1997      AQRVADTAAGWLFWFALAAAIITAVTWTALGH-PDAAVVRAITVLVIACP
TH_2531|M.thermoresistible__bu      AQRIADTAAGWLFWFALGAALLTALVWAVLHR-PDFAVVRTITVLVIACP
Mvan_3678|M.vanbaalenii_PYR-1       GQRFADRAAFWLVLVALIGGTATFLVWWAVGAGVQTALLFAITVVVITCP
                                     **.**  :  :.  ..  .  *   *          .  :::*::*:**

MAV_5246|M.avium_104                CALGLATPTALLVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTT
MSMEG_5014|M.smegmatis_MC2_155      CALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTITT
MLBr_01987|M.leprae_Br4923          CALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVVFDKTGTLTT
Mb0994|M.bovis_AF2122/97            CALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTR
Rv0969|M.tuberculosis_H37Rv         CALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTR
MMAR_4876|M.marinum_M               CALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTR
MUL_0423|M.ulcerans_Agy99           YALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTR
Mflv_0915|M.gilvum_PYR-GCK          HALGLAIPLVVSIATERAARGGVLIKDRLALEGMRTVDAVLFDKTGTLTK
MAB_0449|M.abscessus_ATCC_1997      HALGLAIPLVVSIATERAARGGVLVKDRLALEQMRTVDVVLFDKTGTLTK
TH_2531|M.thermoresistible__bu      HALGLAIPLVVAIATERAARGGVLIKDRIALENMRTVDVVLFDKTGTLTK
Mvan_3678|M.vanbaalenii_PYR-1       DALGLATPTAIMVGTGLGAKRGVLFKNATALETSARIDTVVMDKTGTLTK
                                     ***** * .: :.:  .*  *:*.*.   :*    :*.:::*****:* 

MAV_5246|M.avium_104                GAMTVLDVVAADGTDRATLLRYAGALEAASEHPIAHAIARDAKAELGPLP
MSMEG_5014|M.smegmatis_MC2_155      GSMTLLDVVVADGEDRDDVLRVAAAVEDASEHPIARAIAAGARERTGELP
MLBr_01987|M.leprae_Br4923          GQLKVSAVTAAPGWQANEVLQMAATVESASEHAVALAIAASTTHR----E
Mb0994|M.bovis_AF2122/97            ARMRVTDVIAGQRRQPNQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIP
Rv0969|M.tuberculosis_H37Rv         ARMRVTDVIAGQRRQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIP
MMAR_4876|M.marinum_M               AQMELTDVIAGKRRQPDAVLRIAAAVEAGSEHPIGAAIVAGARERELEIP
MUL_0423|M.ulcerans_Agy99           AQMELTDVIAGKRRQPDVVLRIAAAVESGSEHPIGAAIVAGARERELEVP
Mflv_0915|M.gilvum_PYR-GCK          GEPTVTAIEVRGDLDEGTVLALAAAAEADSEHPLARAIVKAAEERGLTVP
MAB_0449|M.abscessus_ATCC_1997      GTPTLTGIEAAPGHDGDAVLALAAAAETDSEHPLARAIVAAARQRGLDIP
TH_2531|M.thermoresistible__bu      GQPAVTGITAAGAHSEEDVLRLAAAAEAPSEHPLARALVAAAQRHGTDLP
Mvan_3678|M.vanbaalenii_PYR-1       GEPEVTDVVVDG-IPEDQVLAMVAAVETESEHPLAGAIVRYAAAHGIASA
                                    .   :  : .        :*  ..: *  ***.:. *:.  :  .     

MAV_5246|M.avium_104                TPTGFRAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEH
MSMEG_5014|M.smegmatis_MC2_155      AVEGFANIEGLGVQGTVEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQA
MLBr_01987|M.leprae_Br4923          PVANFRAVPGHGVSGTVAERAVRVGKPSWIASR--CNSTTLVTARRNAEL
Mb0994|M.bovis_AF2122/97            AANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEE
Rv0969|M.tuberculosis_H37Rv         AANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEE
MMAR_4876|M.marinum_M               PATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEE
MUL_0423|M.ulcerans_Agy99           PATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEE
Mflv_0915|M.gilvum_PYR-GCK          RASGFSSSPAVGVTATVEGQEIRVGGPRLLDEIGGQE----VHAATSWRE
MAB_0449|M.abscessus_ATCC_1997      AASGFTSEPALGVSAQVAETRVQVGGPALLDARGSRE----LAVAAQWRT
TH_2531|M.thermoresistible__bu      PATDFASTPGLGVRARVAGRTVRVGGPRLLAETGQTA----PAGSEGWRA
Mvan_3678|M.vanbaalenii_PYR-1       SLTGFRNVPGHGAVATVDGRRVAVGNRKLMVEEDVEFGV-LMQRRDELAA
                                        *    . *. . *    : :*    .                    

MAV_5246|M.avium_104                DGKTVVAVGWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNH
MSMEG_5014|M.smegmatis_MC2_155      QGRTAVVVGWDGTARGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNG
MLBr_01987|M.leprae_Br4923          RGETAVFVEIDGEQCGVIAVADAVKASAADAVAALHDRGFRTALLTGDNP
Mb0994|M.bovis_AF2122/97            RGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNA
Rv0969|M.tuberculosis_H37Rv         RGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNA
MMAR_4876|M.marinum_M               RGRTAVFVGQDGQVVGVLAVADTVKDDAADVVRQLHAMGLQVALITGDNA
MUL_0423|M.ulcerans_Agy99           RGRTAVYVGQDGQVVGVLAVADTVKDDAADVVSQLHAMGLQVALITGDNA
Mflv_0915|M.gilvum_PYR-GCK          EGAIILHVVRDGTVLGGLRLADEIRPESREAVDALHKLGVEVVMITGDAE
MAB_0449|M.abscessus_ATCC_1997      EGAIILHVLLDGQVAAALRLADDIRPESADTVKALHKLGVRVVMITGDAQ
TH_2531|M.thermoresistible__bu      RGSTVLYVLVDDMIAGAVALADEIRPESRPTVDALHRQGIDVALITGDAR
Mvan_3678|M.vanbaalenii_PYR-1       SGRTAVLVGVDGRGVGVIALADAVRETSAEAVSALHDLGVEVVMLSGDNQ
                                     *   : *  *.   . : :** ::  :  .:  :   *.   :::**  

MAV_5246|M.avium_104                TVARRTAGELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAA
MSMEG_5014|M.smegmatis_MC2_155      AAARAIADQVGIDDVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAA
MLBr_01987|M.leprae_Br4923          ASAAAVASRIGIDEVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPA
Mb0994|M.bovis_AF2122/97            RTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPA
Rv0969|M.tuberculosis_H37Rv         RTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPA
MMAR_4876|M.marinum_M               RTAAAIAAQVGIDRVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPA
MUL_0423|M.ulcerans_Agy99           RTAAAIAAQVGIDRVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPA
Mflv_0915|M.gilvum_PYR-GCK          AVAQAVGRELGIDRVFAGVRPEDKASKVSALQQEGKKVAMVGDGVNDAPA
MAB_0449|M.abscessus_ATCC_1997      AVADTVAGRLGVDRVFAQVRPQDKAAAVAQLQQEGHTVAMVGDGVNDAPA
TH_2531|M.thermoresistible__bu      SVAESVAAELGIDRVLADVPPEHKAAKVVELQREGRRVAMVGDGVNDAPA
Mvan_3678|M.vanbaalenii_PYR-1       ATADRIAAQLGIDTVIAEVLPGDKAAKIAELQRQGKKVAMVGDGVNDAPA
                                      *   . .:*:  * :   * .*.  :  *:  *: *******:**..*

MAV_5246|M.avium_104                LAAADLGLAMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTN
MSMEG_5014|M.smegmatis_MC2_155      LAQADLGLSMGTGTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGN
MLBr_01987|M.leprae_Br4923          LARADLGMAIGRGTDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFN
Mb0994|M.bovis_AF2122/97            LVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQN
Rv0969|M.tuberculosis_H37Rv         LVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQN
MMAR_4876|M.marinum_M               LVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQN
MUL_0423|M.ulcerans_Agy99           LVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQN
Mflv_0915|M.gilvum_PYR-GCK          LAQADVGIAIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRKMKQN
MAB_0449|M.abscessus_ATCC_1997      LAQADVGIAIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRKMKQN
TH_2531|M.thermoresistible__bu      LARADVGIAIGAGTDVAIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQN
Mvan_3678|M.vanbaalenii_PYR-1       LAQADLGVAIGAGTDVAIETADLVLMRSDPLDVAIALQIGRGTLRKMRQN
                                    *. **:*:::* ****** :..: :  .    .  .: :.  :  .:  *

MAV_5246|M.avium_104                LVWAFGYNLAAIPLAALGMLN-------PMLAGAAMALSSVLVVGNSLRL
MSMEG_5014|M.smegmatis_MC2_155      LFWAFAYNVAALPLAAAGLLN-------PMLAGAAMAFSSVFVVSNSLRL
MLBr_01987|M.leprae_Br4923          MVWAFGYNIAAIPIAAAGLLN-------PLVAGAAMAFSSFFVVSNSLRL
Mb0994|M.bovis_AF2122/97            LGWAFGYNTAAIPLAALGALN-------PVVAGAAMGFSSVSVVTNSLRL
Rv0969|M.tuberculosis_H37Rv         LGWAFGYNTAAIPLAALGALN-------PVVAGAAMGFSSVSVVTNSLRL
MMAR_4876|M.marinum_M               LGWAFGYNTAAIPLAALGVLN-------PVVAGAAMGLSSVSVVTNSLRL
MUL_0423|M.ulcerans_Agy99           LGWAFGYNTAAIPLAALGVLN-------PVVAGAAMGLSSVSVVTNSLRL
Mflv_0915|M.gilvum_PYR-GCK          LWWGAGYNLIAVPLAAGVLAP-IGIVLPMSVGAILMSLSTIVVALNAQLL
MAB_0449|M.abscessus_ATCC_1997      LWWAAGYNLISVPLAAGVAAP-IGFVMPMSAGAVLMSLSTVVVALNSQLL
TH_2531|M.thermoresistible__bu      LWWAAGYNLIAVPLAAGVLAP-AGFVMPMSVGAILMSLSTVVVALNAQLL
Mvan_3678|M.vanbaalenii_PYR-1       LGWAVGYNVIALPIAAGVFVPSLGLVLRPEIAALSMSGSSFIVAVNALML
                                    : *. .**  ::*:**               ..  *. *:. *. *:  *

MAV_5246|M.avium_104                RSFASIIPGA----------------------------------------
MSMEG_5014|M.smegmatis_MC2_155      KRFR----------------------------------------------
MLBr_01987|M.leprae_Br4923          RNFGAILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRPVAHRTGV
Mb0994|M.bovis_AF2122/97            RRFGRDGRTA----------------------------------------
Rv0969|M.tuberculosis_H37Rv         RRFGRDGRTA----------------------------------------
MMAR_4876|M.marinum_M               RRFGRDV-------------------------------------------
MUL_0423|M.ulcerans_Agy99           RRFGRDV-------------------------------------------
Mflv_0915|M.gilvum_PYR-GCK          RRLDLTPEASTRAVLNR---------------------------------
MAB_0449|M.abscessus_ATCC_1997      RRLDLRPQTSARNMLNS---------------------------------
TH_2531|M.thermoresistible__bu      RRLDLRPEQSLAAARR----------------------------------
Mvan_3678|M.vanbaalenii_PYR-1       KRLKLPVPASAEAGAKS---------------------------------
                                    : :                                               

MAV_5246|M.avium_104                ------
MSMEG_5014|M.smegmatis_MC2_155      ------
MLBr_01987|M.leprae_Br4923          KPPTHR
Mb0994|M.bovis_AF2122/97            ------
Rv0969|M.tuberculosis_H37Rv         ------
MMAR_4876|M.marinum_M               ------
MUL_0423|M.ulcerans_Agy99           ------
Mflv_0915|M.gilvum_PYR-GCK          ------
MAB_0449|M.abscessus_ATCC_1997      ------
TH_2531|M.thermoresistible__bu      ------
Mvan_3678|M.vanbaalenii_PYR-1       ------