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MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALDLTDLLPDSDERCADRLTRGL VDDGIIEQAHVIDGDTPKPRLCVHYDAEAASATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTAL VDTLSTIPGVVAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHDGDGADHQHGHGG ISGERTELVFAGLAGALLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFFTVQEAFASVRQGRFEIDFLML VSAAGAAALGEVAEGALLLFLFSVGHALEGYAMGRARRAIEALAELAPKTALVRRGGTGDTVEVSVADLR IGDIVVVRPNMRLAADGFVVAGSSSIDQAPVTGESVPVDKIPVPDVAAAAASPELIDAASRVFAGTINGA GAIEIQVTRLASDSTLARVVRLVAEAQTKTTSTQRFTDRFQRIFVPVVLVGVVLLLFAGFVVDEPFTDTV YRALAVLVAASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVNVLAFDKTGTLTEGRPRIADV CATADSDDAELLRIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRATDVRAVIGRGIVASVEGVEVCIGK TELFTDAAQPPPAELAAEVNRLEQAGRTTMLVRAGDRWLGAIGLMDLPRPEASAVIARLAALGVKNTVML SGDNQRVADAVAAEVGVAHARGDLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGASVGIAMGAAGS DVALETADVALMADDLRALPFAISLSRRSSRVIKQNLWASLGIVAVLIPATIFGLGIGPAVLIHEGSTLI VVANALRLLGMPMQSVTPAAPRVERAEETP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2822 | - | - | 100% (870) | heavy metal translocating P-type ATPase |
| M. gilvum PYR-GCK | Mflv_0906 | - | e-137 | 44.55% (651) | heavy metal translocating P-type ATPase |
| M. gilvum PYR-GCK | Mflv_3179 | - | e-133 | 43.76% (633) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2015c | ctpG | 1e-128 | 40.14% (735) | metal cation transporter P-type ATPase G CtpG |
| M. tuberculosis H37Rv | Rv1992c | ctpG | 1e-128 | 40.14% (735) | metal cation transporter P-type ATPase G CtpG |
| M. leprae Br4923 | MLBr_00747 | ctpC | 1e-90 | 34.89% (642) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_4853c | - | 1e-128 | 40.83% (676) | cation-transporting ATPase G |
| M. marinum M | MMAR_2140 | - | 1e-130 | 40.14% (740) | metal cation transporter p-type ATPase |
| M. avium 104 | MAV_5246 | - | 6e-92 | 35.41% (740) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5403 | cadA | 1e-110 | 38.45% (632) | cadmium-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_2531 | - | 2e-87 | 37.20% (578) | PUTATIVE copper-translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_1477 | ctpD | 1e-102 | 37.22% (634) | cation transporter p-type ATPase D CtpD |
| M. vanbaalenii PYR-1 | Mvan_3700 | - | 0.0 | 94.60% (852) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2015c|M.bovis_AF2122/97 --------------------------------------MTTVVDA----E
Rv1992c|M.tuberculosis_H37Rv --------------------------------------MTTVVDA----E
MMAR_2140|M.marinum_M -------------------------------------MMTTTTAAPRDGG
MAB_4853c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK MPPTRGFAQIGVDESYAHMRIIACMADRNGEKVGRLGADGAPTHRTLALD
Mvan_3700|M.vanbaalenii_PYR-1 ------------------MRIIACMADRNGETVSRPGADGTPTNRTLALD
MSMEG_5403|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1477|M.ulcerans_Agy99 ------------------------------------------------MT
MAV_5246|M.avium_104 --------------------------------------MSTPPRHIDEGT
TH_2531|M.thermoresistible__bu --------------------------------------MVGPAHHG----
MLBr_00747|M.leprae_Br4923 ------------------------------------MTLAMAEQIATADN
Mb2015c|M.bovis_AF2122/97 VQLTVVSDAAGRMRVQATGFQFDAGRAVAIEDTVGKVAGVQAVHAYPRTA
Rv1992c|M.tuberculosis_H37Rv VQLTVVSDAAGRMRVQATGFQFDAGRAVAIEDTVGKVAGVQAVHAYPRTA
MMAR_2140|M.marinum_M AALTVVSAAAGRMRVRASGFRFDAGRAVAIEETVGKVTGVRAVQAFPHTA
MAB_4853c|M.abscessus_ATCC_199 -----MSDACG------------CG------------------HDEPATG
Mflv_2822|M.gilvum_PYR-GCK LTDLLPDSDERCADRLTRGLVDDGIIEQAHVIDGDTPKPRLCVHYDAEAA
Mvan_3700|M.vanbaalenii_PYR-1 LTDLLPGSDERCADRLTRGLVDDGIIEQAHVIDGDTTKPRLCVHYDAEAA
MSMEG_5403|M.smegmatis_MC2_155 MTALYPAVEPAPAARPAR--------------------------------
MUL_1477|M.ulcerans_Agy99 LTAFEVSAAEASSDRSDR--------------------------------
MAV_5246|M.avium_104 FPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVTATVNYATEKAAV
TH_2531|M.thermoresistible__bu ----TVAADGRAQHLTGR---------DHHRHGHG---------------
MLBr_00747|M.leprae_Br4923 PAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCNGVRVVHAYPRTG
Mb2015c|M.bovis_AF2122/97 SIVIWYSRAICDTAAILSAIIDAETVPAAAVPAYASRSASNRKAGVVQKI
Rv1992c|M.tuberculosis_H37Rv SIVIWYSRAICDTAAILSAIIDAETVPAAAVPAYASRSASNRKAGVVQKI
MMAR_2140|M.marinum_M SVVVWYSPGRCDTAGILSAIAEAEHIPAASVPARAPHSADGRRAGVMQRI
MAB_4853c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2822|M.gilvum_PYR-GCK SATEVQRRALEAADTITSMYGHLRWLTTGTHDDMAMRTALVDTLSTIPGV
Mvan_3700|M.vanbaalenii_PYR-1 SATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTALADTLSTMPGV
MSMEG_5403|M.smegmatis_MC2_155 -------------------------PRSG--------GWLWTVPSVR---
MUL_1477|M.ulcerans_Agy99 -------------------------IPSTSVRPLTWRAALWSVMSVR---
MAV_5246|M.avium_104 SAPASYDPQTLITEIENAGYAAAVATPSPPRDDPELASLRRRLVT-----
TH_2531|M.thermoresistible__bu ---------------DHAGHVAEFRR--------LFWVMLLLAVP-----
MLBr_00747|M.leprae_Br4923 SVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAPHSSDIRNIEVLR--
Mb2015c|M.bovis_AF2122/97 IDWSTRTLSGVRRD--------------------VAAQPSGETSDAC-CD
Rv1992c|M.tuberculosis_H37Rv IDWSTRTLSGVRRD--------------------VAAQPSGETSDAC-CD
MMAR_2140|M.marinum_M LDWSARTLSGPRGDGLGRASAV------------VAVRRRRAVSDACGCD
MAB_4853c|M.abscessus_ATCC_199 -------------------------------------------------D
Mflv_2822|M.gilvum_PYR-GCK VAAAATPDSVELEFERTTVTAQELVDVIAAQMAPSGSAADAEAAVAHDGD
Mvan_3700|M.vanbaalenii_PYR-1 IAAVATPDSIELEFERATVTAQELVDVIAAQVAPSRSATPVEAAVAHERD
MSMEG_5403|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1477|M.ulcerans_Agy99 --------------------------------------------------
MAV_5246|M.avium_104 --------------------------------------------------
TH_2531|M.thermoresistible__bu --------------------------------------------------
MLBr_00747|M.leprae_Br4923 --------------------------------------------------
Mb2015c|M.bovis_AF2122/97 GEDNEDREPEQLWQVAKLRRAAFSGVLLTAS-LVAAWAYPLWPVVLGLKA
Rv1992c|M.tuberculosis_H37Rv GEDNEDREPEQLWQVAKLRRAAFSGVLLTAS-LVAAWAYPLWPVVLGLKA
MMAR_2140|M.marinum_M HDDNE-REPQRLWHVRKLRRATLSGALLGAS-VIVAWVTPLGPVVLGMKA
MAB_4853c|M.abscessus_ATCC_199 EVDGE-REPERLWEVSELRFAAVAGVVLLAG-YVVGWTGGSHPVEIGLYA
Mflv_2822|M.gilvum_PYR-GCK GADHQHGHGGISGERTELVFAGLAGALLLTGWLLAAFADTPRSAEVVVYG
Mvan_3700|M.vanbaalenii_PYR-1 GADHQHGHGGIFGERTELVFAGLAGALLLTGWLLAAFADTPRSAEVVVYG
MSMEG_5403|M.smegmatis_MC2_155 -------------------WAAAALALFLTG-LAAQLLGAPQAVVWTLYL
MUL_1477|M.ulcerans_Agy99 -------------------WAGIALALFLTG-LVAQLNGAAEPVWWTLYL
MAV_5246|M.avium_104 -------------------AIALAGPVIAVAMIPALQFQHWHWAALALTA
TH_2531|M.thermoresistible__bu -------------------TVAFSGMFAMILGYQVPRVPGAQWVSPVLGT
MLBr_00747|M.leprae_Br4923 -----------------MAIGAAALTLLGVRRYVFARPLLLPTTSRLVAS
: . . :
Mb2015c|M.bovis_AF2122/97 LALAVGASTFVPSSLKRLAEGRVGVGTLMTIAALGAVALG----------
Rv1992c|M.tuberculosis_H37Rv LALAVGASTFVPSSLKRLAEGRVGVGTLMTIAALGAVALG----------
MMAR_2140|M.marinum_M LALAVGASTFVPSTLKRLAQGRIGVGTLMTIAAAGAVALG----------
MAB_4853c|M.abscessus_ATCC_199 AALAIGAYTFVPSTLRRLARGKIGVGTLMTIAAIGAVILG----------
Mflv_2822|M.gilvum_PYR-GCK LAFFFGAFFTVQEAFASVRQGRFEIDFLMLVSAAGAAALG----------
Mvan_3700|M.vanbaalenii_PYR-1 LAFFFGAFFTVQEAFASVRQGRFEIDFLMLVSAAGAAALG----------
MSMEG_5403|M.smegmatis_MC2_155 ACYVVGGWEPAWVGVRALRNRTLDVDLLMIVAAIGAATIG----------
MUL_1477|M.ulcerans_Agy99 ACYLAGGWGSAWAGAQALRNRALDVDLLMIVAAIGAVAIG----------
MAV_5246|M.avium_104 PVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAAD
TH_2531|M.thermoresistible__bu VMYVWGGRPFLTGAISEIRSRTPGMMLLIGLALTVAFLSS----------
MLBr_00747|M.leprae_Br4923 GVTIFTGYPFLRG---ALRFGKTGTDALVSAATIASLILR----------
. : *: . :
Mb2015c|M.bovis_AF2122/97 --------------------------ELGEAATLAFLFSIS-EGLEEYAT
Rv1992c|M.tuberculosis_H37Rv --------------------------ELGEAATLAFLFSIS-EGLEEYAT
MMAR_2140|M.marinum_M --------------------------QVGEAATLAFLFSIS-EGLEEYAV
MAB_4853c|M.abscessus_ATCC_199 --------------------------EVGEAAMLAFLFSIS-EGLEEYAL
Mflv_2822|M.gilvum_PYR-GCK --------------------------EVAEGALLLFLFSVG-HALEGYAM
Mvan_3700|M.vanbaalenii_PYR-1 --------------------------EIAEGALLLFLFSVG-HALEGYAM
MSMEG_5403|M.smegmatis_MC2_155 --------------------------QVFDGALLIVIFATS-GALEDVAT
MUL_1477|M.ulcerans_Agy99 --------------------------QIFDGALLIVIFATS-GALDDVAT
MAV_5246|M.avium_104 RPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSK
TH_2531|M.thermoresistible__bu -------------WGASLGVLDHRLEFWWELALLIVIMLLG-HWIELRSL
MLBr_00747|M.leprae_Br4923 --------------------------ENVVALAVLWLLNIG-EYLQDLTL
:: . :: :
Mb2015c|M.bovis_AF2122/97 ARTRRGLRALLSLVPDQATVLR-----EGTETIVASTELHVGDQMIVKPG
Rv1992c|M.tuberculosis_H37Rv ARTRRGLRALLSLVPDQATVLR-----EGTETIVASTELHVGDQMIVKPG
MMAR_2140|M.marinum_M ARTRRGLRALLSLVPDQATVLR-----DGSETVLAPAELRVGDQMIVKPG
MAB_4853c|M.abscessus_ATCC_199 ARTRRGLRALLSLAPEEATVLR-----DGTETTITATELQVGDTMLVRPG
Mflv_2822|M.gilvum_PYR-GCK GRARRAIEALAELAPKTALVRRGG---TGDTVEVSVADLRIGDIVVVRPN
Mvan_3700|M.vanbaalenii_PYR-1 GRARRAIEALAELAPKTALVRRGG---TGDTVEVSVADLRVGDIVVVRPN
MSMEG_5403|M.smegmatis_MC2_155 TRTERSVRGLLDLAPEHATLLG-----DGSQRVVAAADLRPGDVIVVRPG
MUL_1477|M.ulcerans_Agy99 KHTADSVKGLLDLAPEQATVFDV----DGNEQVVAASELVVGDRVVVRPG
MAV_5246|M.avium_104 RTAGAALRALLALGAKDVAVLRAG-----AETRIPIERLAVGDEFVVRPG
TH_2531|M.thermoresistible__bu ARTTSALDSLAALLPDTAERVEQGP-DGETVTVVAPADLRVGDTVIVRPG
MLBr_00747|M.leprae_Br4923 RRTRRAISALLSGTQDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEH
: .: .* . . :. : ** .:*:
Mb2015c|M.bovis_AF2122/97 ERLATDGIIRAGRTALDVSAITGESVPVEVGP----------------GD
Rv1992c|M.tuberculosis_H37Rv ERLATDGIIRAGRTALDVSAITGESVPVEVGP----------------GD
MMAR_2140|M.marinum_M ERLATDGIIRAGRTALDVSAITGESVPVEAGP----------------GD
MAB_4853c|M.abscessus_ATCC_199 ERVATDGTITAGRTALNTSAITGESVPVEAGP----------------GD
Mflv_2822|M.gilvum_PYR-GCK MRLAADGFVVAGSSSIDQAPVTGESVPVDKIPVPDVAAAAASPELIDAAS
Mvan_3700|M.vanbaalenii_PYR-1 MRLAADGFVVAGSSSIDQAPVTGESVPVDKNPVPDVAAAAASPELIDAAS
MSMEG_5403|M.smegmatis_MC2_155 ERISADGTVIGGASEVDQSSITGEPLPAAK----------------DVGD
MUL_1477|M.ulcerans_Agy99 ERIPADGAVLSGCSEVDQCSIAGESMPAAK----------------GRGD
MAV_5246|M.avium_104 ERIATDGIVVAGSSAVDAAMLTGESVPVEVG----------------VGD
TH_2531|M.thermoresistible__bu AGIPADGRIIDGVADVDESMVTGESVPVRRG----------------VGD
MLBr_00747|M.leprae_Br4923 VAIPVDGEVIDGEAVVNQSAITGENLPVSVMA----------------GS
:..** : * : :: . ::** :*. ..
Mb2015c|M.bovis_AF2122/97 EVFAGSINGLGVLQVGVTATAANNSLARIVHIVEAEQVRKGASQRLADCI
Rv1992c|M.tuberculosis_H37Rv EVFAGSINGLGVLQVGVTATAANNSLARIVHIVEAEQVRKGASQRLADCI
MMAR_2140|M.marinum_M VVFAASINGSGVLQVQVTATAEDNSLARIVHIVEAEQARKGASQRLADRI
MAB_4853c|M.abscessus_ATCC_199 EVFAGSINGNGVLQVRVSATAADNSLARIVAIVEAEQSRKGASQRLADRI
Mflv_2822|M.gilvum_PYR-GCK RVFAGTINGAGAIEIQVTRLASDSTLARVVRLVAEAQTKTTSTQRFTDRF
Mvan_3700|M.vanbaalenii_PYR-1 RVFAGTINGAGAIEVQVTRLAGDSTLARVVRLVAEAQTKTTSTQRFTDRF
MSMEG_5403|M.smegmatis_MC2_155 DVFAGTVNGSGALRVEVTREPSQTVVARIVAMVTEASATKATTQLFIEKI
MUL_1477|M.ulcerans_Agy99 EVFAGTVNGSGVLQLLVTRDPSQTVVARIVERVSEASATKAKTQLFIEKI
MAV_5246|M.avium_104 GVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRV
TH_2531|M.thermoresistible__bu RVVAATVATDSGLRITVTAVGDDTALAGIRRMVAEAQSSSSRAQRIADTA
MLBr_00747|M.leprae_Br4923 HVHAGSVVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENF
* ..:: . : : .: .. :. : * . * . :
Mb2015c|M.bovis_AF2122/97 ARPLVPSIMIAAALIAGTGSVLGNPL-VWIERALVVLVAAAPCALAIAVP
Rv1992c|M.tuberculosis_H37Rv ARPLVPSIMIAAALIAGTGSVLGNPL-VWIERALVVLVAAAPCALAIAVP
MMAR_2140|M.marinum_M ARPLVPGIMVTGALIAGTGSVLGNPA-VWIERALVVLVAASPCALAIAVP
MAB_4853c|M.abscessus_ATCC_199 AKPLVPAIMITAAAIAVLGSVFGDPL-VWIERALVVLVAASPCALAISVP
Mflv_2822|M.gilvum_PYR-GCK QRIFVPVVLVGVVLLLFAGFVVDEPFTDTVYRALAVLVAASPCALAIATP
Mvan_3700|M.vanbaalenii_PYR-1 QRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVAASPCALAIATP
MSMEG_5403|M.smegmatis_MC2_155 EQRYSAGVVVATLALLTVPLMFGADLRSTLLRAMTFMIVASPCAVVLATM
MUL_1477|M.ulcerans_Agy99 EQRYSIGVVIATLALIAIPLMLGTPVQVVLLRAMTFMIVASPCAVVLATM
MAV_5246|M.avium_104 SGVFVPVVLLLAVATLAGWLAAGGTLATALTAAVAVLIIACPCALGLATP
TH_2531|M.thermoresistible__bu AGWLFWFALGAALLTALVWAVLH-RPDFAVVRTITVLVIACPHALGLAIP
MLBr_00747|M.leprae_Br4923 SRCFVPTSFVVSAITLAIT--------KDVRRTMTVLLIACPCAVGLATP
. : ::..:: *.* *: ::
Mb2015c|M.bovis_AF2122/97 VTVVASIGAASRLGVLIKGGAALETLGTIRAVALDKTGTLTANRPVVIDV
Rv1992c|M.tuberculosis_H37Rv VTVVASIGAASRLGVLIKGGAALETLGTIRAVALDKTGTLTANRPVVIDV
MMAR_2140|M.marinum_M VSVVAAIGAASKFGVLIKGGAALEALGTIGGIALDKTGTLTANRPAVIDV
MAB_4853c|M.abscessus_ATCC_199 VTVVAAIGAASKLGVLVKGGAALEALGVVRTIALDKTGTLTANRPTVIEV
Mflv_2822|M.gilvum_PYR-GCK SAVLSAVARAARAGILMKGGAALEELGRVNVLAFDKTGTLTEGRPRIADV
Mvan_3700|M.vanbaalenii_PYR-1 SAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIADV
MSMEG_5403|M.smegmatis_MC2_155 PPLLSAIANASRHGVLVKSAVAMERLADTDVVVLDKTGTLTAGEPVISRV
MUL_1477|M.ulcerans_Agy99 PPLLSAIADAGRHGVLVKSAIVVEHLADTGVVALDKTGTLTFGLPQLAIV
MAV_5246|M.avium_104 TALLVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDV
TH_2531|M.thermoresistible__bu LVVAIATERAARGGVLIKDRIALENMRTVDVVLFDKTGTLTKGQPAVTGI
MLBr_00747|M.leprae_Br4923 TAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNI
: . ..: *:*:*. :* : :*****:* . : :
Mb2015c|M.bovis_AF2122/97 ATTNGATR-EEVLAVAAALEARSEHPLAVAVLAATQA------TTAASDV
Rv1992c|M.tuberculosis_H37Rv ATTNGATR-EEVLAVAAALEARSEHPLAVAVLAATQA------TTAASDV
MMAR_2140|M.marinum_M ATTNGTTR-EEVLATAAALEARSEHPLAAAILAATQAP-----IAAASDV
MAB_4853c|M.abscessus_ATCC_199 AATAGATG-ERVLSAAAALESRSEHPLAAAILAAAGS------VDPADDV
Mflv_2822|M.gilvum_PYR-GCK CATADSDD-AELLRIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRATDV
Mvan_3700|M.vanbaalenii_PYR-1 CATADSDD-AELLRIAVAVEEQSDHPLARAIVRDGRQRLAGAAIPRATDV
MSMEG_5403|M.smegmatis_MC2_155 TVLIDGA---DVLGMAAAAEQFSEHPLGRAIVAAARGR----VVPEAGDF
MUL_1477|M.ulcerans_Agy99 EPLSADVGIKKLLQLAAAAEQSSEHPLGRAIVEEVRRRGI--TIPGAEDF
MAV_5246|M.avium_104 VAADGTDR-ATLLRYAGALEAASEHPIAHAIARDAKAELG--PLPTPTGF
TH_2531|M.thermoresistible__bu TAAGAHSE-EDVLRLAAAAEAPSEHPLARALVAAAQRHGT--DLPPATDF
MLBr_00747|M.leprae_Br4923 VAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEERHIS--IPPHEEC
:* * : * * **:. *:
Mb2015c|M.bovis_AF2122/97 QAVPGAGLIGRLDGRVVRLGRPGWLDA------AELADHVACMQQAGATA
Rv1992c|M.tuberculosis_H37Rv QAVPGAGLIGRLDGRVVRLGRPGWLDA------AELADHVACMQQAGATA
MMAR_2140|M.marinum_M QAVPGTGLTGHLDGHAVRLGRPGWLDP------ADLADHVARMQQAGATA
MAB_4853c|M.abscessus_ATCC_199 EAVTSAGLTGRRGGHTLRLGRPGWIDP------GSLAPDVARMQQGGATA
Mflv_2822|M.gilvum_PYR-GCK RAVIGRGIVASVEGVEVCIGKTELFTDAAQPPPAELAAEVNRLEQAGRTT
Mvan_3700|M.vanbaalenii_PYR-1 RAVIGRGIVASVDGVEVCIGKTELFTDAAQPPPAELAAEVERLEQAGRTT
MSMEG_5403|M.smegmatis_MC2_155 TALPGRGVRARVAGHVVEVVSPAAYAGENAAVREHCAAIEN----DGGTA
MUL_1477|M.ulcerans_Agy99 RALPGRGVRASVGREFVEVCSPHSYRG---APLPELAPILE----AGATA
MAV_5246|M.avium_104 RAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTV
TH_2531|M.thermoresistible__bu ASTPGLGVRARVAGRTVRVGGPRLLAETGQTAPAGSEGWRAR----GSTV
MLBr_00747|M.leprae_Br4923 EVLVGLGMRTWADGRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETP
. *: : : . *
Mb2015c|M.bovis_AF2122/97 VLVERDQQLLGAIAVRDELRPEAAEVVAGLRTGGYQ-VTMLTGDNHATAA
Rv1992c|M.tuberculosis_H37Rv VLVERDQQLLGAIAVRDELRPEAAEVVAGLRTGGYQ-VTMLTGDNHATAA
MMAR_2140|M.marinum_M VLVERDNQLLGAIAVRDELRPEAAEVIARLRAGRYQ-VSMLTGDNHATAA
MAB_4853c|M.abscessus_ATCC_199 VLVEEDGQLLGAIAVRDELRPEAAHVIAALHRSGYR-VAMLTGDNAATAT
Mflv_2822|M.gilvum_PYR-GCK MLVRAGDRWLGAIGLMDLPRPEASAVIARLAALGVKNTVMLSGDNQRVAD
Mvan_3700|M.vanbaalenii_PYR-1 MLVRAGERWLGAIGLMDLPRPEASAVIARLAELGVKNTVMLSGDNQRVAD
MSMEG_5403|M.smegmatis_MC2_155 VVVLEDGLPVGVIGLADRLRPDAPAAVMQLAQLTKHPPMLLTGDNRRAAG
MUL_1477|M.ulcerans_Agy99 AIVLRNGVAIGVLGLTDQVRADAAPSVAALTALTSAPPVLLTGDNPCAAQ
MAV_5246|M.avium_104 VAVGWDGRARGILALADTVKPSSAAAVRQFTRLGLT-PILLTGDNHTVAR
TH_2531|M.thermoresistible__bu LYVLVDDMIAGAVALADEIRPESRPTVDALHRQGID-VALITGDARSVAE
MLBr_00747|M.leprae_Br4923 LLFAVDGTLVGLISLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAK
. . * :.: * :..: : : :::** *
Mb2015c|M.bovis_AF2122/97 ALAAQAGIEQVHAELRPEDKAHLVAQLRARQP-TAMVGDGVNDAPALAAA
Rv1992c|M.tuberculosis_H37Rv ALAAQAGIEQVHAELRPEDKAHLVAQLRARQP-TAMVGDGVNDAPALAAA
MMAR_2140|M.marinum_M ALAAQAGIEHVYAELRPEDKARLVKELRAQRP-TAMVGDGVNDAPALAAA
MAB_4853c|M.abscessus_ATCC_199 TLARQVGIDTVHADLRPEDKARIITELRQQHP-TAMVGDGVNDAPALATA
Mflv_2822|M.gilvum_PYR-GCK AVAAEVGVAHARGDLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGA
Mvan_3700|M.vanbaalenii_PYR-1 AVAAEVGVAYARGDLMPEDKVAQIAALRERHGRVGMVGDGVNDAPAMAGA
MSMEG_5403|M.smegmatis_MC2_155 RLAEEAGIADVHAELLPDGKAAAVQKLQRDNTHVLVVGDGVNDAPAMAAA
MUL_1477|M.ulcerans_Agy99 RVAQHAGITDVRAALLPEQKVEAVQALQASGHRVLVVGDGVNDAPAMAAA
MAV_5246|M.avium_104 RTAGELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAA
TH_2531|M.thermoresistible__bu SVAAELGIDRVLADVPPEHKAAKVVELQREGRRVAMVGDGVNDAPALARA
MLBr_00747|M.leprae_Br4923 AVATELGIDEWRAEVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAA
* . *: . * * : *: . :********.*:* *
Mb2015c|M.bovis_AF2122/97 DLGIAMGAMGTDVAIETADVALMGQDLRHLPQALDHARRSRQIMVQNVGL
Rv1992c|M.tuberculosis_H37Rv DLGIAMGAMGTDVAIETADVALMGQDLRHLPQALDHARRSRQIMVQNVGL
MMAR_2140|M.marinum_M DLGIAMGAMGTDVAIETADVALMGQDLRHLPQALDHARRSRQIMLQNVGL
MAB_4853c|M.abscessus_ATCC_199 DLGIAMGAMGTDVAIETADVALMGEDLRHLTQALAHARRARTIMLQNVGL
Mflv_2822|M.gilvum_PYR-GCK SVGIAMGAAGSDVALETADVALMADDLRALPFAISLSRRSSRVIKQNLWA
Mvan_3700|M.vanbaalenii_PYR-1 SVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRCSRVIKQNLWA
MSMEG_5403|M.smegmatis_MC2_155 HTSIAMGRAGADLTVQTADVVTIRDELATVPAVIALARRARRVVIANLVM
MUL_1477|M.ulcerans_Agy99 HTSVAMG-AGADPTLQTADGVTVRDELHTIPTLIGLARQARRVVTANLFI
MAV_5246|M.avium_104 DLGLAMG-TGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVW
TH_2531|M.thermoresistible__bu DVGIAIG-AGTDVAIASAGVVLAGSDPRSVLSVLQLSRAAYRKMKQNLWW
MLBr_00747|M.leprae_Br4923 DIGIAMGLAGTDVAVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGM
.:*:* *:* :: :*. . : . : *
Mb2015c|M.bovis_AF2122/97 SLSIITVLMPLALFGILGLAAVVLVHEFTEVIVIANGVRAGRIKPLAGPP
Rv1992c|M.tuberculosis_H37Rv SLSIITVLMPLALFGILGLAAVVLVHEFTEVIVIANGVRAGRIKPLAGPP
MMAR_2140|M.marinum_M SLTIITVLMPLALFGTLGLAAVVLVHEVAEVVVIANGVRAGRIKPLTGNQ
MAB_4853c|M.abscessus_ATCC_199 SLALIAVLIPLALLGILGLAAVVAVHELAEIVVIANGVRAGRTQPLTAPE
Mflv_2822|M.gilvum_PYR-GCK SLGIVAVLIPATIFG-LGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTP
Mvan_3700|M.vanbaalenii_PYR-1 SLGIVAVLIPATVFG-LGIGPAVLIHEGSTLIVVANALRLLGMPMQSINP
MSMEG_5403|M.smegmatis_MC2_155 AGAAITTLVLWDLFGQLPLPLGVAGHEGSTILVALNGLRLLSNRAWISPG
MUL_1477|M.ulcerans_Agy99 AGTFISVLVLWDLFGQLPLPLGVAGHEGSTVLVALNGMRLLTNRSWRAAA
MAV_5246|M.avium_104 AFGYNLAAIPLAA-----LGMLNPMLAGAA-MALSSVLVVGNS-----LR
TH_2531|M.thermoresistible__bu AAGYNLIAVPLAAGVLAPAGFVMPMSVGAILMSLSTVVVALNAQLLRRLD
MLBr_00747|M.leprae_Br4923 SIAVNAAGLFIGAGGALSPVLAAVLHNASSVAVVANSSRLIRYRLD----
: : : .
Mb2015c|M.bovis_AF2122/97 --KTPDRTIPG---
Rv1992c|M.tuberculosis_H37Rv --KTPDRTIPG---
MMAR_2140|M.marinum_M --ARP---------
MAB_4853c|M.abscessus_ATCC_199 HANTPAAQLAQQE-
Mflv_2822|M.gilvum_PYR-GCK --AAPRVERAEETP
Mvan_3700|M.vanbaalenii_PYR-1 --AAPRVERAEETP
MSMEG_5403|M.smegmatis_MC2_155 --ATPT--------
MUL_1477|M.ulcerans_Agy99 --SPVR--------
MAV_5246|M.avium_104 LRSFASIIPGA---
TH_2531|M.thermoresistible__bu LRPEQSLAAARR--
MLBr_00747|M.leprae_Br4923 --------------