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NYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGPAAAAMAAAAAP YAGWLSAAAARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSNWFGLNAPLIAAVEGAYE QMWAADVAAMVGYHSGASAAAEQLVPFQQALQQLPNLGIGNIGNANLGGGNTGDLNTGNGNIGNTNLGSG NRGDANLGSGNIGNSNVGGGNVGNGNFGSGNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNN NVGTGNAGSGNIGAGNTGSSNWGFGNNGIGNIGFGNTGNGNIGFGLTGNNQVGIGGLNSGSGNIGLFNSG TNNVGFFNSGNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGSLNTGMGNAGGVNTGFGNGGAI NLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGSLNTGFGAVGTG SGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGFGNTGAQTVGIANSGVLNSGFF NSGVHNSGGFNSENQRSGFGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3533c | PPE62 | - | 100% (582) | PPE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 62.79% (602) | PPE family protein |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | 0.0 | 58.67% (617) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3563c | PPE62 | 0.0 | 100.00% (582) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 5e-35 | 29.06% (609) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01182 | - | 9e-30 | 40.54% (185) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-29 | 33.73% (418) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4554 | - | 0.0 | 57.53% (671) | PPE family protein |
| M. avium 104 | MAV_4704 | - | 4e-53 | 54.04% (198) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-29 | 31.50% (454) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 1e-25 | 38.50% (187) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0964 | - | 0.0 | 56.22% (635) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-39 | 29.76% (615) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3563c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3563c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3563c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3563c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv ------------------------------------------MN---YAV
Mb3563c|M.bovis_AF2122/97 ------------------------------------------MN---YAV
MMAR_4554|M.marinum_M ------------------------------------------MN---FSI
MUL_0964|M.ulcerans_Agy99 ------------------------------------------MN---FMM
MAV_4704|M.avium_104 ------------------------------------------MTNPHFAW
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------MFDFAA
TH_3113|M.thermoresistible__bu ------------------------------------------------MA
MAB_4284c|M.abscessus_ATCC_199 ---------------------MSIIDFILNLFRDPVEAASYVADPEAALA
Rv3533c|M.tuberculosis_H37Rv LPPELNSLRMFTGAGSAPMLAAAVAWDG--------LAAELGSAASSFGS
Mb3563c|M.bovis_AF2122/97 LPPELNSLRMFTGAGSAPMLAAAVAWDG--------LAAELGSAASSFGS
MMAR_4554|M.marinum_M FPPEINSLRMFTGAGSAPMLQAAAAWEG--------LAGELGSAADSFAS
MUL_0964|M.ulcerans_Agy99 LPPEVNSALMFTGAGSAPTLAAATAWDG--------LVAELGEAAEAFSS
MAV_4704|M.avium_104 LPPEVNSALIYSGPGPGPLLAAAAAWDG--------LAEELASSAQSFSS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 LSPETNSTRMYLGPGSSPILTAAAAWVV--------LAKELTAAAQGLQS
TH_3113|M.thermoresistible__bu LPPEVHSTLLRTGPGPGALSAAADAWRM--------LSDEYRAAAVELAA
MAB_4284c|M.abscessus_ATCC_199 NAGLSAVSAAQVGAVMPVVAESVASNYG--------YQSQWVNTGNPIHD
* . : .
Rv3533c|M.tuberculosis_H37Rv VTSD---------LASQAWQGP---AAAAMAAAAAPYAGWLSAAAARAAG
Mb3563c|M.bovis_AF2122/97 VTSD---------LASQAWQGP---AAAAMAAAAAPYAGWLSAAAARAAG
MMAR_4554|M.marinum_M VTSG---------LVGQAWQGP---ASAAMAAAVAPYTSWLSAAAAQAVG
MUL_0964|M.ulcerans_Agy99 VTSG---------LASGSWQGP---AAAAMAAAAAPYAGWLSAAATRALG
MAV_4704|M.avium_104 VTSD---------LASGSWQGA---SSAAMMTVANQYVSWLSAAAAQAEE
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGG---NGGVGVVGATGAVG--APGVAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGG---NGGVGIAGATGAVG--APGVAGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGG---AGGVGADGTSAHVDGGTGGTGGTGG
MLBr_01182|M.leprae_Br4923 AVEA----------LLTTFEGE---SAAALAERVTPYEKWLTQNAASAEL
TH_3113|M.thermoresistible__bu VVSQT---------CATAWEGV---GADAYAAAHGPYLFWLTDTAAAAAA
MAB_4284c|M.abscessus_ATCC_199 LSGNLQN------YYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP
*
Rv3533c|M.tuberculosis_H37Rv AAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSN-----------
Mb3563c|M.bovis_AF2122/97 AAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSN-----------
MMAR_4554|M.marinum_M AAGAAKMVASAFEAARAATVLPAAVAANRNALVQMVMSN-----------
MUL_0964|M.ulcerans_Agy99 AATQAKAAAAVFESAQAATVHPELVLANRNQLVSLVLSN-----------
MAV_4704|M.avium_104 VSHQASAIATAFEVALAATVQPAVVAANRALVQALAATN-----------
Mflv_5091|M.gilvum_PYR-GCK ATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------
Mvan_1264|M.vanbaalenii_PYR-1 ATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP
MLBr_01182|M.leprae_Br4923 TATQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSN-----------
TH_3113|M.thermoresistible__bu AGAQLEAAAAAHASALAAMPTMAELTANRTTHAALVATN-----------
MAB_4284c|M.abscessus_ATCC_199 IASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG------DGA
Rv3533c|M.tuberculosis_H37Rv --WFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGAS-------------
Mb3563c|M.bovis_AF2122/97 --WFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGAS-------------
MMAR_4554|M.marinum_M --IFGQNAPAIAAAEAAYEEMWAQDVAAMFGYHSGAS-------------
MUL_0964|M.ulcerans_Agy99 --LFGQNAPAIAATESTYEELWAQDVAATVGYHGGAS-------------
MAV_4704|M.avium_104 --WLGQNTPAIADIEAAYEQMWASDVAAMFGYHADAS-------------
Mflv_5091|M.gilvum_PYR-GCK --AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG---
Mvan_1264|M.vanbaalenii_PYR-1 --AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG---
MSMEG_0868|M.smegmatis_MC2_155 NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV
MLBr_01182|M.leprae_Br4923 --IFGQNSTAIAEKEAEYTEMWIQDAAAMTSYQ-----------------
TH_3113|M.thermoresistible__bu --FFGVNTIPIAVNEADYARMWIQAATTMATYEAVAS-------------
MAB_4284c|M.abscessus_ATCC_199 VAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSN-------------
* .
Rv3533c|M.tuberculosis_H37Rv ---------------------------------------AAAEQLVPFQQ
Mb3563c|M.bovis_AF2122/97 ---------------------------------------AAAEQLVPFQQ
MMAR_4554|M.marinum_M ---------------------------------------AVAAALSPWEQ
MUL_0964|M.ulcerans_Agy99 ---------------------------------------AVAAQLAPWQQ
MAV_4704|M.avium_104 ---------------------------------------AAVAKLPPWNE
Mflv_5091|M.gilvum_PYR-GCK ----AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ----VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAG
MSMEG_0868|M.smegmatis_MC2_155 DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG
MLBr_01182|M.leprae_Br4923 ---------------------------------------ASVLEAVGATK
TH_3113|M.thermoresistible__bu ----------------------------------------AAVSATPRTV
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------VGVDQSQTRVGG
Rv3533c|M.tuberculosis_H37Rv ALQQLP------------------------------------NLGIGNIG
Mb3563c|M.bovis_AF2122/97 ALQQLP------------------------------------NLGIGNIG
MMAR_4554|M.marinum_M LLQNVPALSPLAAIG----------------------NLGAGNLGFGNTG
MUL_0964|M.ulcerans_Agy99 AIQALPGRVAAMATTGPAASAAAALASGPAAALDIGNNGSGNFLSIGNIG
MAV_4704|M.avium_104 VLQNLG---------------------------------------FSNAS
Mflv_5091|M.gilvum_PYR-GCK GLGETGTTGGAGGVG--------------------GQGTAGGTGGVGGIG
Mvan_1264|M.vanbaalenii_PYR-1 TAGETGVTGGVGGIG--------------------GQGTEGGTGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
MLBr_01182|M.leprae_Br4923 AFTAPP-------------------------------------LGVNEVG
TH_3113|M.thermoresistible__bu APPPILG------------------------------------AGTGESA
MAB_4284c|M.abscessus_ATCC_199 DYTNVSGHGSADIDKS---------------------VTVVDDHSQRNTT
Rv3533c|M.tuberculosis_H37Rv NAN-----------------------------------------------
Mb3563c|M.bovis_AF2122/97 NAN-----------------------------------------------
MMAR_4554|M.marinum_M IAN-----------------------------------------------
MUL_0964|M.ulcerans_Agy99 NNN-----------------------------------------------
MAV_4704|M.avium_104 TAV-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG----------STGAVGG-------VGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1 GVG----------ATGGAGG-------VGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
MLBr_01182|M.leprae_Br4923 LAQ-----------------------------------------------
TH_3113|M.thermoresistible__bu TAA-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NIN-----------------------------------------------
Rv3533c|M.tuberculosis_H37Rv -----LGGGNTGDLNTGNGNIGNTNLGSGNRG----------------DA
Mb3563c|M.bovis_AF2122/97 -----LGGGNTGDLNTGNGNIGNTNLGSGNRG----------------DA
MMAR_4554|M.marinum_M -----LGNGNTGNLNFGGGNIGNFNFGSGNRGG---------------NV
MUL_0964|M.ulcerans_Agy99 -----LGSGNTGSANLGGGNIGNGNLGSGNTG----------------NV
MAV_4704|M.avium_104 -----TRPAGSGAVARG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
MLBr_01182|M.leprae_Br4923 -----EVVEEVVEEVVEEVVEAEQAIS--------------------QAA
TH_3113|M.thermoresistible__bu ----ITGAHVTAELRAAESRTLLDEINELIDR--------------LFAP
MAB_4284c|M.abscessus_ATCC_199 -----DSFNTDRSTNIGSGNTTNTEIGSHNQAN----------------I
Rv3533c|M.tuberculosis_H37Rv NLGSGNIGNSNVG--------------------GGNVGNGNF--------
Mb3563c|M.bovis_AF2122/97 NLGSGNIGNSNVG--------------------GGNVGNGNF--------
MMAR_4554|M.marinum_M NFGNGNNGFFNLG--------------------GGNIGSNNF--------
MUL_0964|M.ulcerans_Agy99 NLGNGNNGFFNFG--------------------NGNLGDTNF--------
MAV_4704|M.avium_104 -YTSRIAGFLAPR--------------------APQ--------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
MLBr_01182|M.leprae_Br4923 LDQAVNEG------------------------------------------
TH_3113|M.thermoresistible__bu LFPPGFADALP---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVG---------------------GNAGLAGN--------
.
Rv3533c|M.tuberculosis_H37Rv ------------------------GSGN---GRAGLP-------------
Mb3563c|M.bovis_AF2122/97 ------------------------GSGN---GRAGLP-------------
MMAR_4554|M.marinum_M ------------------------GSGNRGNGNIGFGNYQSTGGANIGGG
MUL_0964|M.ulcerans_Agy99 ------------------------GSGN--SGNLNLG-------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------AGLAGNAG------------
Rv3533c|M.tuberculosis_H37Rv --GSGNVGNGNLGNSNLGSGN-TGNSNVGFGNTGNNNVGTGNAGSGNIGA
Mb3563c|M.bovis_AF2122/97 --GSGNVGNGNLGNSNLGSGN-TGNSNVGFGNTGNNNVGTGNAGSGNIGA
MMAR_4554|M.marinum_M NSGSGNKGFGNTGNYNIGSGN-FGSFNFGDGNRGSNNFGFGNTNSGNVGF
MUL_0964|M.ulcerans_Agy99 ---SGNR----FGSGNIGFGNRFGDGNFGSGNAGSYNFGTGNNGSFNIGS
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG-GTGGT
Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG-GTGGT
MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTG-GHGGD
MLBr_01182|M.leprae_Br4923 -----------MEATVVPQVDQQVNVDVATPQTAVPDSSSAAAPQLWGGF
TH_3113|M.thermoresistible__bu ------------DGLLGTLLAPLLPGATGDGPPMATIMSFLLMGLSNPAY
MAB_4284c|M.abscessus_ATCC_199 -----LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG--NAGL
Rv3533c|M.tuberculosis_H37Rv GNTGSSNWGFGNNGIGNIGFGNTGNGNIG--------------FGLTGNN
Mb3563c|M.bovis_AF2122/97 GNTGSSNWGFGNNGIGNIGFGNTGNGNIG--------------FGLTGNN
MMAR_4554|M.marinum_M GNLGANNVGFGNLGSGNVGFGNTGNNNFG--------------IGLSGND
MUL_0964|M.ulcerans_Agy99 GNNGDSNIGFGNLGTNNLGFGNNGSNNIG--------------FGLSGSN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
MLBr_01182|M.leprae_Br4923 AQHLSPINDTLSMINNHAGMANAGLSLVN---------------------
TH_3113|M.thermoresistible__bu LFPVLVYLLFTGVVHTTVAVSGMLAQLVP---------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAG----------------LAGNA
Rv3533c|M.tuberculosis_H37Rv QVGIG---------------GLNSGSGNIGLFNSGTNNVGFFNS------
Mb3563c|M.bovis_AF2122/97 QVGIG---------------GLNSGSGNIGLFNSGTNNVGFFNS------
MMAR_4554|M.marinum_M QVGINF-------------NGLNGGSGNIGLFNSGNNNVGFFNS------
MUL_0964|M.ulcerans_Agy99 QIGIG---------------GLNAGIGNMGFGNAGDNNVGFFNS------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRA
MLBr_01182|M.leprae_Br4923 --------------------GMGSAMKSLAPTTTKAAESAFKAMG-----
TH_3113|M.thermoresistible__bu ---------------------LMPALLPVAVAALGGLAGVWAGLS-----
MAB_4284c|M.abscessus_ATCC_199 GLAGN---------------AGLAGNAGLAGNAGLAGNAGLAGN------
Rv3533c|M.tuberculosis_H37Rv -------------GNGNLGIGNSSDANVG---------------------
Mb3563c|M.bovis_AF2122/97 -------------GNGNLGIGNSSDANVG---------------------
MMAR_4554|M.marinum_M -------------GDGNWGIGNSGDTNTG---------------------
MUL_0964|M.ulcerans_Agy99 -------------GSNNIGFFNSGDGNFG---------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGQGG-LGGGGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGGQGG-LGGVGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTA
MLBr_01182|M.leprae_Br4923 ------------SAVQSTGRGLLGSSSGG---------------------
TH_3113|M.thermoresistible__bu -------------GLAGLAGLTAVPAADG---------------------
MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAAVAGNAAVAG---------------------
Rv3533c|M.tuberculosis_H37Rv ------IGNSGATVG-PFV--AGHNT----------GFGNSGSLNTGMGN
Mb3563c|M.bovis_AF2122/97 ------IGNSGATVG-PFV--AGHNT----------GFGNSGSLNTGMGN
MMAR_4554|M.marinum_M ------IGNSGSFNT-GFVNAASLNTGMANSANTCLGVGNSGAGDVGFMN
MUL_0964|M.ulcerans_Agy99 ------FAHAG--STNT-------------------GFWNSGGTNTGFGN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
MSMEG_0868|M.smegmatis_MC2_155 TDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGG
MLBr_01182|M.leprae_Br4923 ---------------------------------------HVTAQLGRAAS
TH_3113|M.thermoresistible__bu ------------------------------------GASAAPVPAGGPSL
MAB_4284c|M.abscessus_ATCC_199 ------NAAVAGNAAVGGVLNTGVSG------AIGGSSHVGGAINESLGG
Rv3533c|M.tuberculosis_H37Rv AGGVNTGFGNGGAINLGFGNSGQLNAGSFNAGSINTGNFNSG--------
Mb3563c|M.bovis_AF2122/97 AGGVNTGFGNGGAINLGFGNSGQLNAGSFNAGSINTGNFNSG--------
MMAR_4554|M.marinum_M AGHDNVGLGNAGSFNMGFGNAGSGNVGYENAGGANVGFGNSG--------
MUL_0964|M.ulcerans_Agy99 GGSLNFGFGNGGVENMGHGNAGSFNMGFGNGGGGNTGFYNSG--------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK FGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGS
Mvan_1264|M.vanbaalenii_PYR-1 FGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGS
MSMEG_0868|M.smegmatis_MC2_155 NGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGY
MLBr_01182|M.leprae_Br4923 IGSLRVPQTWTTASQPVTAATRALSPARVAVATESESAPLLG--------
TH_3113|M.thermoresistible__bu PSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAGHSVPPAPHSAP-------
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGG--------
Rv3533c|M.tuberculosis_H37Rv QGNTGDFNAGVRNTGWSNSGLTN----------------TGAFNAGSLNT
Mb3563c|M.bovis_AF2122/97 QGNTGDFNAGVRNTGWSNSGLTN----------------TGAFNAGSLNT
MMAR_4554|M.marinum_M SDNTGFLNSGSVNTGFLNSGSTN----------------TGAGNSGEVNT
MUL_0964|M.ulcerans_Agy99 TYNTGFSNAAETNTGWENSGNVN----------------TGGYNSGGLNT
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG
MLBr_01182|M.leprae_Br4923 ---GGLPMAPMVPGGGSGTGGVN----------------------TALRL
TH_3113|M.thermoresistible__bu --PVGTSGPPYLIAAQPAPGVARR--------------SAGARRAASIVE
MAB_4284c|M.abscessus_ATCC_199 ---SGSVGGSTAVGGGAHTGVGGG-------------VSTGVGVGSHVGG
Rv3533c|M.tuberculosis_H37Rv GFGAVGTGSGPNSGFG---------------NAGTNNSGFFNTGVGSSGF
Mb3563c|M.bovis_AF2122/97 GFGAVGTGSGPNSGFG---------------NAGTNNSGFFNTGVGSSGF
MMAR_4554|M.marinum_M GFGIATDSGATNSGFG---------------NTGSGNSGFNNDGNDNSGF
MUL_0964|M.ulcerans_Agy99 GIGSPDTQAGPNSGFG---------------HSGSGNSGFFNSGDGNSGF
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGA
MLBr_01182|M.leprae_Br4923 QPRAFVMPRNPAAG------------------------------------
TH_3113|M.thermoresistible__bu PAGSAAAAAAARESAP-------------IRRRRGQKDGLHGHRHEHQQP
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGST--------------AVGGGAHTGVGGGVNTGVGV
Rv3533c|M.tuberculosis_H37Rv QNGGS----------------NNSGLQNAVGT--------VIAAGFGN--
Mb3563c|M.bovis_AF2122/97 QNGGS----------------NNSGLQNAVGT--------VIAAGFGN--
MMAR_4554|M.marinum_M QNTGTSSEGFGNVGN------NQTGFQNTGGTNTGFFNTGTNDVGVGNSA
MUL_0964|M.ulcerans_Agy99 ENSNTCVS-----AN------GHSGVRNSGDA---------TNVGFSN--
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTS
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu ASMSAATAP------------SAAGIRVLGGAG-----------------
MAB_4284c|M.abscessus_ATCC_199 GSHVGGGISESLGGS-----GSVGGSTAVGGGAHTSAINDALGGSGSVG-
Rv3533c|M.tuberculosis_H37Rv ---------TGAQTVGIANS-------------------------GVLNS
Mb3563c|M.bovis_AF2122/97 ---------TGAQTVGIANS-------------------------GVLNS
MMAR_4554|M.marinum_M NLNIGFWNSTGAGNVGVMNTGTDNSGF---------------IQTGTANS
MUL_0964|M.ulcerans_Agy99 ---------SGSNNTGIFNTGTFNTGI---------------ANSGSDSS
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu ---------RISRTRG-----------------------------SVPHA
MAB_4284c|M.abscessus_ATCC_199 ---------GSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSH
Rv3533c|M.tuberculosis_H37Rv GFFNSGVHNSGGFNSENQRSGFGN-------
Mb3563c|M.bovis_AF2122/97 GFFNSGVHNSGGFNSENQRSGFGN-------
MMAR_4554|M.marinum_M GFANSGTSSSGGLNKGDQQSGFGN-------
MUL_0964|M.ulcerans_Agy99 GLLISGTNSSGALNSGDDQSGFNN-------
MAV_4704|M.avium_104 -------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 -------------------------------
TH_3113|M.thermoresistible__bu EITPGDPTEPSSPTDRAHRPAEPN-------
MAB_4284c|M.abscessus_ATCC_199 GAAGTGFEAQGHAQGHASETAHTTLPGAEHH