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MTRINPIDLSFLLLERANRPNHMAAYTIFEKPKGQKSSFGPRLFDAYRHSQAAKPFNHKLKWLGTDVAAW ETVEPDMGYHIRHLALPAPGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHALIDG EGGLRAMRNFLSDSPDDTTLAGPWMSAQGADRPRRTPATVSRRAQLQGQLQGMIKGLTKLPSGLFGVSAD AADLGAQALSLKARKASLPFTARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA LHHYLAEHQASTDRPLVAFMPMSLREKSGEGGGNRVSAELVPMGAPKASPVERLKEINAATTRAKDKGRG MQTTSRQAYALLLLGSLTVADALPLLGKLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNV TFASINTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3088 | - | - | 100% (474) | hypothetical protein Rv3088 |
| M. tuberculosis H37Rv | Rv3740c | - | 5e-56 | 33.55% (465) | hypothetical protein Rv3740c |
| M. tuberculosis H37Rv | Rv3734c | - | 7e-52 | 29.70% (468) | hypothetical protein Rv3734c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3115 | - | 0.0 | 100.00% (474) | hypothetical protein Mb3115 |
| M. gilvum PYR-GCK | Mflv_1058 | - | 2e-48 | 29.24% (472) | hypothetical protein Mflv_1058 |
| M. leprae Br4923 | MLBr_01244 | - | 6e-19 | 22.30% (426) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 7e-46 | 27.59% (464) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_2598 | - | 0.0 | 69.18% (464) | hypothetical protein MMAR_2598 |
| M. avium 104 | MAV_0355 | - | 6e-53 | 32.42% (472) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 2e-54 | 31.65% (474) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 2e-48 | 30.40% (477) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3162 | - | 1e-145 | 66.15% (390) | hypothetical protein MUL_3162 |
| M. vanbaalenii PYR-1 | Mvan_2903 | - | 3e-54 | 31.40% (465) | hypothetical protein Mvan_2903 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPPEG-AGRNFVR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPPDD-AGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPPVD-AGPDYAE
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPPAD-APRDYLR
Rv3088|M.tuberculosis_H37Rv ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-QKSSFGP
Mb3115|M.bovis_AF2122/97 ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-QKSSFGP
MMAR_2598|M.marinum_M --MNTNRISPIDLS----FLLLERPNRPFHMTAFTIFQKPKG-QHSSFGS
MUL_3162|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2903|M.vanbaalenii_PYR-1 ---MNAAIPPLDLG----WLLMESPGGTTHVGAMLLFKKPPG--RGSLVR
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDT---TPDWN
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
Rv3088|M.tuberculosis_H37Rv RLFDAYRHSQAAKPFN----HKLKWLGTDVAAWETVEPDMGYHIRHLALP
Mb3115|M.bovis_AF2122/97 RLFDAYRHSQAAKPFN----HKLKWLGTDVAAWETVEPDMGYHIRHLALP
MMAR_2598|M.marinum_M RLFDAYRHSRAIEPFN----YRLSWLGRNVARWEIVEPDMRNHVQHIVLP
MUL_3162|M.ulcerans_Agy99 ---------------------------------------MRNHLQHIVLP
Mvan_2903|M.vanbaalenii_PYR-1 EIVEAYRGYRPLPPFN---YVPELLGAGAPHFREAESWDPHYHVQHLSLP
MLBr_01244|M.leprae_Br4923 RFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
*::: :.
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
Rv3088|M.tuberculosis_H37Rv APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
Mb3115|M.bovis_AF2122/97 APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
MMAR_2598|M.marinum_M GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
MUL_3162|M.ulcerans_Agy99 GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
Mvan_2903|M.vanbaalenii_PYR-1 AHSSYEDLLRLVADLHEPMLDRHRPMFRCWLIDGVPGGRFAIYTKTHHSI
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
:. . : :* :* : :::*: ** *: : *::
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSD-PDDPEIRAPWTLPKR--SRKAG--PSS-----
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSED-PSDTTVRVPWNLPRRESSRRAG--SSS-----
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTD-PGD-DARVPWNLPPPR-RNPAG--PVS-----
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDD-PDARDCQAVWAPAKRRAKSSIV--STTNTSAI
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTD-PASRDTRMFFNVPSPTRSRRDPGAAESSNPLT
Rv3088|M.tuberculosis_H37Rv IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
Mb3115|M.bovis_AF2122/97 IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
MMAR_2598|M.marinum_M IDGEGGLRAMRGFLSTS-PHDKTLAGPWMPAPSARAPRRPQPRVSRRQWL
MUL_3162|M.ulcerans_Agy99 IDGEGGLRAMRGFLSTS-PHDKTLAGPWMPAPSARAPRR--------QWL
Mvan_2903|M.vanbaalenii_PYR-1 IDGVSGLRKLYEGLTLS-AEPAIPTPPFAMPHPKSEAAAPTPALR-----
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLP--
** . . . . .
MAV_0355|M.avium_104 ------RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPF
MSMEG_6322|M.smegmatis_MC2_155 ------LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPF
TH_2030|M.thermoresistible__bu ------RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPF
MAB_4544c|M.abscessus_ATCC_199 D-----LVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPL
Mflv_1058|M.gilvum_PYR-GCK A-----TLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSV
Rv3088|M.tuberculosis_H37Rv QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARK------ASLPF
Mb3115|M.bovis_AF2122/97 QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARK------ASLPF
MMAR_2598|M.marinum_M QRGLT----GIAKLPSDLVGMVGDAVDLGAQALQLKPQR------GALPF
MUL_3162|M.ulcerans_Agy99 QRGLT----GIAKLPSDLAGMVGDAVDLGAQALQLKPQR------GALPF
Mvan_2903|M.vanbaalenii_PYR-1 -----KLTHAIHTAVTQIGAVNQISLGASRKALSAVLGS---HVEGSLPF
MLBr_01244|M.leprae_Br4923 ----VALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQA
: . :
MAV_0355|M.avium_104 GAPRTMLN-VKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGA
MSMEG_6322|M.smegmatis_MC2_155 GAPRTMFN-VKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGA
TH_2030|M.thermoresistible__bu GAPRTMFN-VRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGA
MAB_4544c|M.abscessus_ATCC_199 SAPHTMLN-VSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGA
Mflv_1058|M.gilvum_PYR-GCK SAPHSILN-ARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGG
Rv3088|M.tuberculosis_H37Rv TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
Mb3115|M.bovis_AF2122/97 TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
MMAR_2598|M.marinum_M AASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDA
MUL_3162|M.ulcerans_Agy99 AASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDA
Mvan_2903|M.vanbaalenii_PYR-1 VASHAPTN-APPRQARGFATLSLPLQEMHRIGRRHGATLNDLAAAVIDHG
MLBr_01244|M.leprae_Br4923 AEPSPLLR--QRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGA
. . : :: . ::** : .
MAV_0355|M.avium_104 LRYYLLEQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDD
MSMEG_6322|M.smegmatis_MC2_155 LRAYLAEQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVED
TH_2030|M.thermoresistible__bu LRQYLLEHDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDD
MAB_4544c|M.abscessus_ATCC_199 LRTYLEEQNALPDKPLVAMCPVSIRAEGDQNAG-NSITALLANLATDKPD
Mflv_1058|M.gilvum_PYR-GCK LRKFLSDFDKLPDRSLIAFLPVNVRPKGD-EGGGNAVGAILAPMGTDIED
Rv3088|M.tuberculosis_H37Rv LHHYLAEHQASTDRPLVAFMPMSLR-EKSGEGGGNRVSAELVPMGAPKAS
Mb3115|M.bovis_AF2122/97 LHHYLAEHQASTDRPLVAFMPMSLR-EKSGEGGGNRVSAELVPMGAPKAS
MMAR_2598|M.marinum_M LHHYLDEHRAPADRPLVALMPMSMR-SQAG--AGNQVSAELIAMGAPKAN
MUL_3162|M.ulcerans_Agy99 LHHYLDEHRAPADGPLVALMPMSMR-SQAG--AGNQVSAELIAMGAPKAN
Mvan_2903|M.vanbaalenii_PYR-1 LHSYLREVGQDHPHEFIAMCPVSLR-EDGDSAVGTRVSAIFVRLGKPEAS
MLBr_01244|M.leprae_Br4923 LRRYHEALGVSIS-TLPMAVPVNVRTEADVVGSNRFVGVTLAAP-LGTND
*: : : *:.:* : .
MAV_0355|M.avium_104 PAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSSLALA---AVPGWV
MSMEG_6322|M.smegmatis_MC2_155 PADRLAVIRRSITDNKRVFSELPRLQALALSALLIAPLGLTT--AFPGFV
TH_2030|M.thermoresistible__bu PAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAPLGLG---AVPGVV
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTG---AVPGLV
Mflv_1058|M.gilvum_PYR-GCK PVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQ
Rv3088|M.tuberculosis_H37Rv PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVAD--ALPLLG
Mb3115|M.bovis_AF2122/97 PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVAD--ALPLLG
MMAR_2598|M.marinum_M LRQRLKQVNQATTAAKDKGNGMKSPSRQAYTLSLFASLAMSD--VLPGFG
MUL_3162|M.ulcerans_Agy99 LRQRLKQVSQATTAAKDKGDGMKSPSRQAYTLSLFASLAMSD--VLPGFG
Mvan_2903|M.vanbaalenii_PYR-1 MVDRLRQVARSVAIAKEELGALSADAAMTYAVALVALAGAG---ASTHLD
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRRDE----PAMNIIGSLAPLMTVLPAS----VLDFI
*: : :
MAV_0355|M.avium_104 SATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASN
MSMEG_6322|M.smegmatis_MC2_155 DATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSN
TH_2030|M.thermoresistible__bu SSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTN
MAB_4544c|M.abscessus_ATCC_199 DRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSS
Mflv_1058|M.gilvum_PYR-GCK PPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSY
Rv3088|M.tuberculosis_H37Rv --KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
Mb3115|M.bovis_AF2122/97 --KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
MMAR_2598|M.marinum_M --KAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASV
MUL_3162|M.ulcerans_Agy99 --KAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASV
Mvan_2903|M.vanbaalenii_PYR-1 RVGHPACNLVISNIPGGNATRYLNGAQLMGIFPVSALAASIGLNVTLTSY
MLBr_01244|M.leprae_Br4923 VDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSR
. :: **: . : * : . .: . :
MAV_0355|M.avium_104 AGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------------
MSMEG_6322|M.smegmatis_MC2_155 AHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA------------
TH_2030|M.thermoresistible__bu ADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------------
MAB_4544c|M.abscessus_ATCC_199 GSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-------------
Mflv_1058|M.gilvum_PYR-GCK ADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI------------
Rv3088|M.tuberculosis_H37Rv NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
Mb3115|M.bovis_AF2122/97 NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
MMAR_2598|M.marinum_M NEQLCLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADS
MUL_3162|M.ulcerans_Agy99 NEQLCLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADS
Mvan_2903|M.vanbaalenii_PYR-1 CDHMDFGFVANTAAISDVHALAEHTRRAFAECTAKTRVT-----------
MLBr_01244|M.leprae_Br4923 GGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAA
. . : : .: :
MAV_0355|M.avium_104 -------------
MSMEG_6322|M.smegmatis_MC2_155 -------------
TH_2030|M.thermoresistible__bu -------------
MAB_4544c|M.abscessus_ATCC_199 -------------
Mflv_1058|M.gilvum_PYR-GCK -------------
Rv3088|M.tuberculosis_H37Rv -------------
Mb3115|M.bovis_AF2122/97 -------------
MMAR_2598|M.marinum_M A------------
MUL_3162|M.ulcerans_Agy99 A------------
Mvan_2903|M.vanbaalenii_PYR-1 -------------
MLBr_01244|M.leprae_Br4923 RSSGSPAGWLSSS